Book.
0000 - Gale Group | NCCO-STM 1of2
Ethel Ciampi, Reinaldo Uribe-San-Martín, Claudia Cárcamo, Juan Pablo Cruz, Ana Reyes, Diego Reyes, Carmen Pinto, Macarena Vásquez, Rafael A. Burgos, Juan L. Hancke,
Abstract Background Multiple sclerosis (MS) is a chronic immune mediated disease and the progressive phase appears to have significant neurodegenerative mechanisms. The classification of the course of progressive MS (PMS) has been re-organized into categories of active vs. not active inflammatory disease and the presence vs. absence of gradual disease progression. Clinical trial experience to date in PMS with anti-inflammatory medications has shown limited effect. Andrographolide is a new class of ...
Tópico(s): Ginseng Biological Effects and Applications
2020 - BioMed Central | BMC Neurology
... Lorenzo de Aldana, Francisco Carvajal, Francisco Pizzaro and Diego Almagro. The texts conclude with a lengthy series ...
1558 - Gale Group | World Scholar Latin America
Diego A. Vasco, Carlos Salinas-Lira, Ignacio Barra-Reyes, Diego Elustondo,
Tópico(s): Textile materials and evaluations
2018 - Springer Science+Business Media | European Journal of Wood and Wood Products
... Lorenzo de Aldana, Francisco Carvajal, Francisco Pizzaro and Diego Almagro. The texts conclude with a lengthy series ...
1558 - Gale Group | World Scholar Latin America
Alfonso Urzúa, Alejandra Caqueo‐Urízar, Diego Henríquez, Marcos Domic‐Siede, Daniel Acevedo, Sebastian Ralph, Gonzalo Reyes, Diego Tang,
There is abundant evidence about the negative impact of discrimination on well-being, but less research on factors that can reduce this negative effect, mainly focused on North American samples and with incipient development on South–South migration. The objective of this research was to analyze the effect of ethnic identity on the relationship between the experience of racial and ethnic discrimination and psychological well-being in Colombian immigrants living in Chile. A total of 962 immigrants ...
Tópico(s): Employment and Welfare Studies
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Sebastián Reyes-Cerpa, Eva Vallejos‐Vidal, M.J. Gonzalez-Bown, Jonathan Reyes, Diego Pérez-Stuardo, Deborah Vargas, Mónica Imarai, Víctor Cifuentes, Eugenio Spencer, Ana María Sandino, Felipe E. Reyes‐López,
Salmon farming may face stress due to the intensive culture conditions with negative impacts on overall performance. In this aspect, functional feed improves not only the basic nutritional requirements but also the health status and fish growth. However, to date no studies have been carried out to evaluate the effect of functional diets in salmon subjected to crowding stress. Thus, the aim of this study was to evaluate the effect of yeast extract (Xanthophyllomyces dendrorhous; diet A) and the combination ...
Tópico(s): Aquaculture Nutrition and Growth
2018 - Elsevier BV | Fish & Shellfish Immunology
Dindo Reyes, Diego O. Andrey, Antoinette Monod, William L. Kelley, Gongyi Zhang, Ambrose L. Cheung,
ABSTRACT The agr locus of Staphylococcus aureus is composed of two divergent transcripts (RNAII and RNAIII) driven by the P2 and P3 promoters. The P2-P3 intergenic region comprises the SarA/SarR binding sites and the four AgrA boxes to which AgrA binds. We reported here the role of AgrA, SarA, and SarR on agr P2 and P3 transcription. Using real-time reverse transcription (RT)-PCR and promoter fusion studies with selected single, double, triple, and complemented mutants, we showed that AgrA is indispensable ...
Tópico(s): Bacterial Genetics and Biotechnology
2011 - American Society for Microbiology | Journal of Bacteriology
Marco Aurelio Reyes, Diego Hayashi Alonso, J.R. Arias, A. Velázquez,
An experimental and theoretical/numerical study is presented on the behaviour of a vertically placed vapour chamber based heat spreader (190 mm × 140 mm × 15 mm) intended for avionics applications. The experiments were performed with the heat spreader inserted in a mock-up avionics box. The volumetric flow of cooling air was in the range of 5–25 m3/h, that represents current aeronautics on-board conditions and projected values for the mid-term future. Natural convection conditions were also studied because ...
Tópico(s): Heat Transfer and Boiling Studies
2012 - Elsevier BV | Applied Thermal Engineering
Naoki Tajiri, Sandra Acosta, Gabriel S. Portillo-Gonzales, Daniela Aguirre, Stephanny Reyes, Diego Lozano, Mibel Pabon, Ike Dela Peña, Xunming Ji, Takao Yasuhara, Isao Date, Marianna A. Solomita, Ivana Antonucci, Liborio Stuppia, Yuji Kaneko, Cesar V. Borlongan,
Accumulating preclinical evidence suggests the use of amnion as a source of stem cells for investigations of basic science concepts related to developmental cell biology, but also for stem cells' therapeutic applications in treating human disorders. We previously reported isolation of viable rat amniotic fluid-derived stem (AFS) cells. Subsequently, we recently reported the therapeutic benefits of intravenous transplantation of AFS cells in a rodent model of ischemic stroke. Parallel lines of investiagtions ...
Tópico(s): Pluripotent Stem Cells Research
2014 - Frontiers Media | Frontiers in Cellular Neuroscience
María Fernández‐Reyes, Diego Vicente, María José Barahona Gomáriz, Olatz Esnal, Joseba Landa, Eider Oñate, Emilio Pérez‐Trallero,
ABSTRACT The prevalence of extended-spectrum-β-lactamase-producing Enterobacteriaceae (ESBLPE) was studied in stool samples from 125 8- to 16-month-old healthy children. Twenty-four percent of them and 10.7% of the 318 fecal samples studied yielded extended-spectrum-β-lactamase-producing Escherichia coli , with the types being SHV-12, CTX-M-1, CTX-M-14, and TEM-52, the most common types of β-lactamases. This high prevalence of ESBLPE in healthy people, which is to our knowledge the highest currently ...
Tópico(s): Urinary Tract Infections Management
2014 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Aníbal M. Reyes, Diego S. Vazquez, Ari Zeida, Martín Hugo, Marı́a Dolores Piñeyro, María Inés De Armas, Darío A. Estrı́n, Rafael Radí, Javier Santos, Madia Trujillo,
Mycobacterium tuberculosis (M. tuberculosis) is the intracellular bacterium responsible for tuberculosis disease (TD). Inside the phagosomes of activated macrophages, M. tuberculosis is exposed to cytotoxic hydroperoxides such as hydrogen peroxide, fatty acid hydroperoxides and peroxynitrite. Thus, the characterization of the bacterial antioxidant systems could facilitate novel drug developments. In this work, we characterized the product of the gene Rv1608c from M. tuberculosis, which according to ...
Tópico(s): Enzyme function and inhibition
2016 - Elsevier BV | Free Radical Biology and Medicine
Yeimy González‐Giraldo, Rodrigo E. González-Reyes, Diego A. Forero,
Tópico(s): Genomic variations and chromosomal abnormalities
2016 - Elsevier BV | Psychiatry Research
Leonor Y. Vargas-Méndez, Pedro Sanabria, Laura M. Saavedra-Reyes, Diego R. Merchán-Arenas, Vladímir V. Kouznetsov,
The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, Spodoptera frugiperda (J.E. Smith). Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest. During structure-activity relationship studies and physicochemical profile analysis, it was found that ...
Tópico(s): Insect Resistance and Genetics
2018 - Elsevier BV | Saudi Journal of Biological Sciences
Maria Elena Silva, Simona Lange, Bryan Hinrichsen, Amber R. Philp, Carolina R. Reyes, Diego Halabí, Josselyne Mansilla, Peter Rotheneichner, Alerie Guzman de la Fuente, Sébastien Couillard‐Després, Luis Federico Bátiz, Robin J.M. Franklin, Ludwig Aigner, Francisco J. Rivera,
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Upon demyelination, oligodendrocyte progenitor cells (OPCs) are activated and they proliferate, migrate and differentiate into myelin-producing oligodendrocytes. Besides OPCs, neural stem cells (NSCs) may respond to demyelination and generate oligodendrocytes. We have recently shown that CNS-resident pericytes (PCs) respond to demyelination, proliferate and secrete Laminin alpha2 (Lama2) that, in turn, ...
Tópico(s): Barrier Structure and Function Studies
2019 - Frontiers Media | Frontiers in Cellular Neuroscience
Alison Reedy, María Lucía Guerrero Farías, Luis H. Reyes, Diego Pradilla,
Preparing work-ready chemical engineering graduates is achieved by integrating the technical skills and knowledge learned at university with employability skills required by industry. While this is most often made through industry placements, non-placement forms of work-integrated learning (WIL) can be highly effective in preparing graduates for the workplace without the issues of locating work placements and ensuring their quality. In this paper, the authors focus on a chemical engineering course ...
Tópico(s): Higher Education Learning Practices
2020 - Elsevier BV | Education for Chemical Engineers
Angela Harris, Emine N. Fidan, Natalie Nelson, R. E. Emanuel, Theo Jass, Sophia Kathariou, Jeffrey Niedermeyer, Mahmoud Sharara, Francis L. de los Reyes, Diego Riveros‐Iregui, Jill R. Stewart,
Hurricane Florence brought unprecedented rainfall and flooding to Eastern North Carolina in 2018. Extensive flooding had the potential to mobilize microbial contaminants from a variety of sources. Our study evaluated microbial contaminants in surface waters at 40 sites across Eastern North Carolina 1 week after the hurricane made landfall (Phase 1) and one month later (Phase 2). High concentrations of Escherichia coli were detected in flowing channel and floodwater samples across both phases; however, ...
Tópico(s): Vibrio bacteria research studies
2021 - American Chemical Society | ACS ES&T Water
Edinson Puentes-Cala, Valentina Tapia-Perdomo, Daniela Espinosa-Valbuena, María Andrea Reyes-Reyes, Diego Quintero-Santander, Silvia Vasquez-Dallos, Henry Salazar, Pedro Santamaría-Gálvis, Ramón Silva-Rodríguez, Genis Castillo‐Villamizar,
Microorganisms have evolved to inhabit virtually all environments on the planet, from oceanic hot-seeps to pipelines transporting crude and refined hydrocarbons. Often microbial colonization of man-made structures results in the reduction of their service life requiring preemptive or corrective human intervention. Microbiologically Influenced Corrosion (MIC) is caused by a set of intricate bioelectrochemical interactions between a diverse group of microorganisms and metallic surfaces. The complexity ...
Tópico(s): Concrete Corrosion and Durability
2022 - Frontiers Media | Frontiers in Environmental Science
Blake Thomson, Roberto Tapia‐Conyer, Ben Lacey, Sarah Lewington, Raúl Ramírez-Reyes, Diego Aguilar-Ramírez, Louisa Gnatiuc, William G. Herrington, Jason Torres, Eirini Trichia, Rachel Wade, Rory Collins, Richard Peto, Pablo Kuri‐Morales, Jesús Alegre-Díaz, Jonathan Emberson,
Abstract Background Research is needed to determine the relevance of low-intensity daily smoking to mortality in countries such as Mexico, where such smoking habits are common. Methods Prospective study of 159 755 Mexican adults recruited from 1998–2004 and followed for cause-specific mortality to 1 January 2018. Participants were categorized according to baseline self-reported smoking status. Confounder-adjusted mortality rate ratios (RRs) at ages 35–89 were estimated using Cox regression, after ...
Tópico(s): Global Public Health Policies and Epidemiology
2021 - Oxford University Press | International Journal of Epidemiology
Jaime Santos‐Reyes, Diego Padilla-Pérez, Alan N. Beard,
"Critical infrastructures" are exceedingly complex and highly interconnected. In order to gain a full understanding and comprehensive awareness of the risks associated with critical infrastructures it becomes essential to consider in a coherent way all the aspects that may cause a failure of such systems. That is, there is a need for a systemic approach to interdependencies among critical infrastructures. The article presents the application of a systemic safety management system (SSMS) model to ...
Tópico(s): Supply Chain Resilience and Risk Management
2014 - Taylor & Francis | Human and Ecological Risk Assessment An International Journal
Joel Salazar‐Mendiguchía, Roberto Barriales‐Villa, Luís R. Lopes, Juan Pablo Ochoa, Alejandro Rodríguez-Vilela, Julián Palomino-Doza, José M. Larrañaga‐Moreira, Marcos Cicerchia, Ivonne Cárdenas-Reyes, Diego García-Giustiniani, Noël Brögger, Germán Fernández, Soledad García, Lisi Santiago, Paula Vélez, Martín Ortiz-Genga, Perry Elliott, Lorenzo Monserrat,
Up to 50% of patients with hypertrophic cardiomyopathy (HCM) show no disease-causing variants in genetic studies. Mutations in CSRP3 have been associated with HCM, but evidence supporting pathogenicity is inconclusive. In this study, we describe an HCM cohort with a missense variant in CSRP3 (p.Cys150Tyr) with supporting evidence for pathogenicity and a description of the associated phenotype. CSRP3 was sequenced in 6456 index cases with a diagnosis of HCM and in 5012 probands with other cardiomyopathies. ...
Tópico(s): Williams Syndrome Research
2020 - Elsevier BV | European Journal of Medical Genetics
Irene Meta, Feliu Serra-Burriel, José C. Carrasco-Jiménez, Fernando Cucchietti, Carla Diví-Cuesta, Carlos García Calatrava, David García-Sánchez, Eduardo Graells-Garrido, Germán Navarro, Quim Làzaro, Patricio Reyes, Diego Navarro-Mateu, Alex Gil Julian, Imanol Eguskiza Martínez,
In this paper, the Camp Nou stadium is used as a testbed for City Physiology, a theoretical framework for urban digital twins. With this case study, the modularity and adaptability of the framework, originally intended for city‐scale simulations, are tested on a large facility venue. As a proof of concept, several statistical techniques and an agent‐based simulation platform are coupled to simulate a crowd in the stadium, and a process of four steps is followed to build the case study. Both the ...
Tópico(s): Traffic control and management
2021 - Hindawi Publishing Corporation | Complexity
Iria G. Dopeso‐Reyes, Diego Sucunza, Alberto J. Rico, Diego Pignataro, David Marín-Ramos, Elvira Roda, Ana I. Rodríguez‐Pérez, José L. Labandeira‐García, José L. Lanciego,
Glucocerebrosidase (GCase) is a lysosomal enzyme encoded by the GBA1 gene. Mutations in GBA1 gene lead to Gaucher's disease, the most prevalent lysosomal storage disorder. GBA1 mutations reduce GCase activity, therefore promoting the aggregation of alpha-synuclein, a common neuropathological finding underlying Parkinson's disease (PD) and dementia with Lewy bodies. However, it is also worth noting that a direct link between GBA1 mutations and alpha-synuclein aggregation indicating cause and effect ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2017 - Springer Science+Business Media | Brain Structure and Function
Margarita Majem, Manuel Cobo, Dolores Isla, Diego Márquez-Medina, Delvys Rodríguez‐Abreu, Joaquín Casal‐Rubio, Teresa Moran-Bueno, Reyes Bernabé, Diego Pérez-Parente, Pedro Ruiz‐Gracia, Marta Marina Arroyo, Luis Paz‐Ares,
Programmed cell death-ligand 1 (PD-L1) has emerged as a potential biomarker for selection of patients more likely to respond to immunotherapy and as a prognostic factor in non-small cell lung cancer (NSCLC). In this network meta-analysis, we aimed to evaluate the efficacy of first-line anti-PD-(L)1 monotherapy in advanced NSCLC patients with high PD-L1 expression (≥50%) compared to platinum-based chemotherapy. We also evaluated efficacy outcomes according to tumor mutational burden (TMB). To that end, ...
Tópico(s): Lung Cancer Research Studies
2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Yuji Kaneko, Naoki Tajiri, Meaghan Staples, Stephanny Reyes, Diego Lozano, Paul R. Sanberg, Thomas B. Freeman, Harry van Loveren, Seung Up Kim, Cesar V. Borlongan,
We propose that stem cell therapy may be a potent treatment for metastatic melanoma in the brain. Here we discuss the key role of a leaky blood-brain barrier (BBB) that accompanies the development of brain metastases. We review the need to characterize the immunological and inflammatory responses associated with tumor-derived BBB damage in order to reveal the contribution of this brain pathological alteration to the formation and growth of brain metastatic cancers. Next, we discuss the potential ...
Tópico(s): Cancer Cells and Metastasis
2015 - SAGE Publishing | Cell Transplantation
Ever Peralta-Reyes, Diego Vizarretea-Vásquez, Reyna Natividad, Aïtor Aizpuru, Edson E. Robles-Gómez, Claudia Alanis, Alejandro Regalado-Méndez,
The electrochemical reforming of glycerol was carried out in a batch-stirred electrochemical tank reactor equipped with stainless steel electrodes. A response surface methodology constituted by a Face-Centered Central Composite Design was performed to establish the optimal operational conditions to produce hydrogen. Studied parameters were glycerol concentration (CG), current intensity (I) and temperature (T), while chosen responses were hydrogen and oxygen concentrations (CH2 and CO2). A maximum CH2 ( ...
Tópico(s): Advanced battery technologies research
2022 - Elsevier BV | Journal of environmental chemical engineering
Mercedes López, Cristián Pereda, Gabriela Segal, Leonel Muñoz, Raquel Aguilera, Fermín E. González, Alejandro Escobar, Alexandra Ginesta, Diego Reyes, Rodrigo González, Ariadna Mendoza‐Naranjo, Milton Larrondo, Alvaro Compán, Carlos Ferrada, Flavio Salazar‐Onfray,
Purpose The aim of this work was to assess immunologic response, disease progression, and post-treatment survival of melanoma patients vaccinated with autologous dendritic cells (DCs) pulsed with a novel allogeneic cell lysate (TRIMEL) derived from three melanoma cell lines. Patients and Methods Forty-three stage IV and seven stage III patients were vaccinated four times with TRIMEL/DC vaccine. Specific delayed type IV hypersensitivity (DTH) reaction, ex vivo cytokine production, and regulatory T-cell ...
Tópico(s): Immune Cell Function and Interaction
2009 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Raquel Aguilera, Carlos Saffie, Andrés Tittarelli, Fermín E. González, Marcos Ramírez, Diego Reyes, Cristián Pereda, Daniel Hevia, Tamara García‐Salum, Lorena Salazar, Arturo Ferreira, Marcela A. Hermoso, Ariadna Mendoza‐Naranjo, Carlos Ferrada, Paola Garrido, Mercedes López, Flavio Salazar‐Onfray,
This study characterizes, biologically and clinically, a novel type of dendritic cells (DC) produced in the short term and called tumor antigen-presenting cells (TAPCells). In particular, we identified factors present in a lysate derived from heat-shocked allogeneic melanoma cells (TRIMEL) that are associated with TAPCells' enhanced capability to induce CD8(+) T-cell responses in vitro and in vaccinated melanoma patients.First, extensive phenotypic and functional characterization of TAPCells was performed, ...
Tópico(s): T-cell and B-cell Immunology
2011 - American Association for Cancer Research | Clinical Cancer Research
Luis E. Calderón‐Aguilera, Víctor H. Rivera‐Monroy, Luciana Porter‐Bolland, Angelina Martínez‐Yrízar, Lydia B. Ladah, Miguel Martínez‐Ramos, Javier Alcocer, Ana Luisa Santiago-Pérez, Héctor A. Hernández‐Arana, Víctor Manuel Reyes Gómez, Diego R. Pérez‐Salicrup, Vicente Díaz‐Núñez, Joaquín Sosa Ramírez, Jorge A. Herrera‐Silveira, Alberto Búrquez,
Tópico(s): Ecology and Vegetation Dynamics Studies
2012 - Springer Science+Business Media | Biodiversity and Conservation
Angélica Olivo-Dı́az, Mirza Romero‐Valdovinos, Areli Gudiño-Ramírez, Jesús Reyes-Gordillo, Diego Emiliano Jiménez-González, María Elena Ramírez-Miranda, Williams Arony Martínez-Flores, Fernando Martínez‐Hernández, Ana Flisser, Pablo Maravilla,
Tópico(s): Breastfeeding Practices and Influences
2012 - Springer Science+Business Media | Parasitology Research