I. B. Zborovskaya, Alexander V. Gasparian, Appolon Karseladze, Irina Elcheva, Е. А. Трофимова, Keltouma Driouch, Martine Trassard, Alexander Tatosyan, Rosette Lidereau,
... Moscow, RussiaSearch for more papers by this authorKeltouma Driouch, Keltouma Driouch Oncogénétique, Centre René Huguenin, St-Cloud, FranceSearch for ... Moscow, RussiaSearch for more papers by this authorKeltouma Driouch, Keltouma Driouch Oncogénétique, Centre René Huguenin, St-Cloud, FranceSearch for ... were detected by PCR amplification with standard methods (Driouch et al., 1998). Products were loaded on 6% ... labeled with 32P-dCTP by terminal deoxynucleotidyl transferase (Driouch et al., 1998). Table II. POLYMORPHIC MARKERS USED ...
Tópico(s): RNA modifications and cancer
1999 - Wiley | International Journal of Cancer
Mohammed Ajjoun, Jamila Fakchich, Mostafa Elachouri,
... ethnobotanical knowledge coupled to Berber community living in "Driouch province" (Northeastern region of Morocco). This study aimed ... 2017 and August 2019 in several regions within Driouch province. Ethnobotanical data were collected using standard methods ... present study revealed that the people living in Driouch province holds significant knowledge about medicinal plant resources. ... these herbs for healthcare. Keywords: Ethnobotanical, Medicinal plants, Driouch province, Morocco.
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2021 - University of Hawaii Press | Ethnobotany Research and Applications
Rebeca Sanz‐Pamplona, Ramón Aragüés, Keltouma Driouch, Berta Martín, Baldo Oliva, Miguel Gil‐Gil, Susana Boluda, Pedro L. Fernández, Antonio Pérez‐Martínez, Vı́ctor Moreno, J.J. Acebes, Rosette Lidereau, Fabien Reyal, Marc J. van de Vijver, Àngels Sierra,
... Garcia T. Castronovo V. Teti A. Lidereau R. Driouch K. A six-gene signature predicting breast cancer ... Garcia T. Castronovo V. Teti A. Lidereau R. Driouch K. A six-gene signature predicting breast cancer ... Garcia T. Castronovo V. Teti A. Lidereau R. Driouch K. A six-gene signature predicting breast cancer ...
Tópico(s): Lung Cancer Research Studies
2011 - Elsevier BV | American Journal Of Pathology
Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, Naïma Abda, Mohammed Bellaoui,
... followed respectively by Taourirt, Oujda-Angad, Berkane, Nador-Driouch and Jerada. Clear variation in the distribution of ... 4), Jerada (287.8), Taourirt (269.3), Nador-Driouch (213.6) and Figuig (194.4). Trends in ... while an increasing trend was observed in Nador-Driouch, Taourirt and Figuig.For the first time, our ...
Tópico(s): Multiple and Secondary Primary Cancers
2016 - Public Library of Science | PLoS ONE
Rania El Botty, Ludivine Morriset, Élodie Montaudon, Zakia Tariq, Anne Schnitzler, Marina Bacci, Nicla Lorito, Laura Sourd, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Héloïse Derrien, Sophie Vacher, Julien Masliah‐Planchon, Virginie Raynal, Sylvain Baulande, Thibaut Larcher, Anne Vincent‐Salomon, Guillaume Dutertre, Paul Cottu, Géraldine Gentric, Fatima Mechta‐Grigoriou, Scott Hutton, Keltouma Driouch, Ivan Bièche, Andrea Morandi, Elisabetta Marangoni,
Abstract Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients’ tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell lines we demonstrate that a fraction of metastatic ER + BC is highly reliant on oxidative phosphorylation (OXPHOS). Treatment by the OXPHOS inhibitor IACS-010759 strongly inhibits tumour growth in multiple ...
Tópico(s): Cancer-related Molecular Pathways
2023 - Nature Portfolio | Nature Communications
Hicham Gueddari, Mustapha Akodad, Mourad Baghour, Abdelmajid Moumen, Alí Skalli, Yassine El Yousfi, Ahmed Mohsen Ismail, Mohamed Chahban, Ghizlane Azizi, Hanane Ait Hmeid, Muhammad Zahid,
... development in the Oued Kert basin (Mediterranean zone, Driouch province, eastern Morocco); 46 samples (45 wells and ...
Tópico(s): Groundwater flow and contamination studies
2022 - Elsevier BV | Scientific African
Karim Taouis, Keltouma Driouch, Rosette Lidereau, François Lallemand,
The WW domain-containing oxidoreductase gene (WWOX) was cloned 21 years ago as a putative tumor suppressor gene mapping to chromosomal fragile site FRA16D. The localization of WWOX in a chromosomal region frequently altered in human cancers has initiated multiple current studies to establish its role in this disease. All of this work suggests that WWOX, due to its ability to interact with a large number of partners, exerts its tumor suppressive activity through a wide variety of molecular actions ...
Tópico(s): Moyamoya disease diagnosis and treatment
2021 - Multidisciplinary Digital Publishing Institute | Cells
Céline Callens, Keltouma Driouch, Anaïs Boulai, Zakia Tariq, Aurélie Comte, Frédérique Berger, Lisa Belin, Ivan Bièche, Vincent Servois, Patricia Legoix, Virginie Bernard, Sylvain Baulande, Walid Chemlali, François‐Clément Bidard, Virginie Fourchotte, Anne Vincent‐Salomon, Étienne Brain, Rosette Lidereau, Thomas Bachelot, Mahasti Saghatchian, Mario Campone, Sylvie Giacchetti, B Zafrani, Paul Cottu,
Abstract Background Prognosis evaluation of advanced breast cancer and therapeutic strategy are mostly based on clinical features of advanced disease and molecular profiling of the primary tumor. Very few studies have evaluated the impact of metastatic subtyping during the initial metastatic event in a prospective study. The genomic landscape of metastatic breast cancer has mostly been described in very advanced, pretreated disease, limiting the findings transferability to clinical use. Methods ...
Tópico(s): Cancer Cells and Metastasis
2021 - BioMed Central | Genome Medicine
Hicham Gueddari, Mustapha Akodad, Mourad Baghour, Abdelmajid Moumen, Alí Skalli, Yassine El Yousfi, Ait Hmeid Hanane, Mohamed Chahban, Ghizlane Azizi, Rahhou Abderahmane, Ahmed Ismail, Muhammad Zahid,
... quality of the Oued Kert basin (Mediterranean area, Driouch province, eastern Morocco) by collecting 46 samples following ...
Tópico(s): Water Quality and Pollution Assessment
2021 - Wiley | Environmental Quality Management
Francesco Pantano, Martine Croset, Keltouma Driouch, Natalia Bednarz‐Knoll, Michele Iuliani, Giulia Ribelli, Edith Bonnelye, Harriet Wikman, Sandra Geraci, Florian Bonin, Sonia Simonetti, Bruno Vincenzi, Saw See Hong, Sofia Sousa, Klaus Pantel, Giuseppe Tonini, Daniele Santini, Philippe Clézardin,
Bone metastasis remains a major cause of mortality and morbidity in breast cancer. Therefore, there is an urgent need to better select high-risk patients in order to adapt patient's treatment and prevent bone recurrence. Here, we found that integrin alpha5 (ITGA5) was highly expressed in bone metastases, compared to lung, liver, or brain metastases. High ITGA5 expression in primary tumors correlated with the presence of disseminated tumor cells in bone marrow aspirates from early stage breast cancer ...
Tópico(s): Cellular Mechanics and Interactions
2021 - Springer Nature | Oncogene
Sarra Aourabi, M. Driouch, M. Sfaira, Fatima Mahjoubi, B. Hammouti, Chandrabhan Verma, Eno E. Ebenso, Lei Guo,
The present study aims to prepare a phenolic extract of Ammi visnaga from its areal part and qualitative measurement of flavonoids and tannins present in the extract using Folin Ciacalteu and Quettier-Deleu methods. Antioxidant activities of different fractions of the extract was measured using DPPH•, FRAP, β-carotene and total antioxidant capacity techniques. The n-butanol and ethyl acetate fractions designated as F3 and F6, respectively. Corrosion inhibition effect of quercetin and catechin and ...
Tópico(s): Marine Biology and Environmental Chemistry
2020 - Elsevier BV | Journal of Molecular Liquids
El Hassan El Assiri, M. Driouch, Jamila Lazrak, Zakariae Bensouda, Ali Elhaloui, M. Sfaira, Taoufiq Saffaj, Mustapha Taleb,
Statistical modeling of the corrosion inhibition process by twenty-one pyridazine derivatives for mild steel in acidic medium was investigated by the quantitative structure property relationship (QSPR) approach. This modeling was established by the correlation between the corrosion inhibition efficiency (IE %) and a number of the electronic and structural properties of these inhibitors such as: the EHOMO (highest occupied molecular orbital energy), the ELUMO (lowest unoccupied molecular orbital energy), ...
Tópico(s): Concrete Corrosion and Durability
2020 - Elsevier BV | Heliyon
Élodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Fariba Némati, Sophie Vacher, Walid Chemlali, Julien Masliah‐Planchon, Sophie Château‐Joubert, Camilla Rega, Mariana Ferreira Leal, Nikiana Simigdala, Sunil Pancholi, Ricardo Ribas, Nicolás André, Didier Meseure, Anne Vincent‐Salomon, Cécile Réyès, Audrey Rapinat, David Gentien, Thibaut Larcher, Mylène Bohec, Sylvain Baulande, Virginie Bernard, Didier Decaudin, Florence Coussy, Muriel Le Romancer, Guillaume Dutertre, Zakia Tariq, Paul Cottu, Keltouma Driouch, Ivan Bièche, Lesley‐Ann Martin, Elisabetta Marangoni,
A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Here we perform whole exome sequencing and gene expression analysis of matched primary breast tumours and bone metastasis-derived patient-derived xenografts (PDX). Transcriptomic analyses reveal enrichment of the G2/M checkpoint and up-regulation of Polo-like kinase 1 (PLK1) in PDX. PLK1 inhibition results in tumour shrinkage ...
Tópico(s): Cancer-related Molecular Pathways
2020 - Nature Portfolio | Nature Communications
Sarra Aourabi, M. Driouch, M. Sfaira, Fatima Mahjoubi, B. Hammouti, Khadijah M. Emran,
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2019 - Elsevier BV | International Journal of Electrochemical Science
O. El Ghani, Ismael Driouch, Hassan Chatei,
Abstract In this study, a detailed investigation of the problem of sheath is presented using the fluid model in a magnetized three‐component dusty plasma system comprising positive ions, dust grains with variable charge and q ‐non‐extensive electrons (i.e., the electrons evolve far away from their Maxwellian thermodynamic equilibrium [ q = 1]). The effects of q ‐non‐extensivity parameter on the plasma sheath parameters are studied numerically. A significant change is observed in the quantities characterizing ...
Tópico(s): Solar and Space Plasma Dynamics
2019 - Wiley | Contributions to Plasma Physics
Mustapha Beniken, M. Driouch, M. Sfaira, B. Hammouti, M. Ebn Touhami, Mahmoud A. Mohsin,
Tópico(s): Concrete and Cement Materials Research
2018 - Springer Science+Business Media | Journal of Bio- and Tribo-Corrosion
El Hassan El Assiri, M. Driouch, Zakariae Bensouda, Fayssal Jhilal, Taoufiq Saffaj, M. Sfaira, Y. Abboud,
The inhibition ability of six bis-benzimidazole derivatives against corrosion of mild steel in acidic medium was modeled by the electronic and lipophilic descriptors such as: the energy of the highest occupied molecular orbital (E HOMO ), the energy of the lowest unoccupied molecular orbital (E LUMO ), the dipole moment (μ), the molecular critical volume (V c ), the inhibitor concentration (C i ), the logarithm of the partition coefficient (log P), and the molecular mass (M), by means of quantitative structure property ...
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
2018 - Taylor & Francis | Desalination and Water Treatment
Zakariae Bensouda, M. Driouch, R.A. Belakhmima, M. Sfaira, M. Ebn Touhami, Abdellah Farah,
Thymus Sahraouian essential oil (TSEO), as a new corrosion eco-friendly inhibitor, has been used to protect mild steel in 1 M HCl.Weight loss, three potentiodynamic polarization methods (Tafel, Stern and Stern-Geary), and electrochemical impedance spectroscopy measurements were undertaken to evaluate corrosion inhibition by TSEO.TSEO acted as an efficient corrosion inhibitor for mild steel in 1 M HCl, and its inhibition efficiency increased with a concentration of 77.82 % at 2 g L -1 .The polarization ...
Tópico(s): Inorganic and Organometallic Chemistry
2018 - | Portugaliae electrochimica acta
Omar Belmehdi, Abdeltif El Harsal, Mourad Benmoussi, Yousif Laghmouchi, Nadia Skali Senhaji, Jamal Abrini,
... O. elongatum harvested from Temsamane area belonging to Driouch province (North-east of Morocco) at post-flowering ...
Tópico(s): Essential Oils and Antimicrobial Activity
2018 - Elsevier BV | Biocatalysis and Agricultural Biotechnology
Mustapha Beniken, M. Driouch, M. Sfaira, B. Hammouti, M. Ebn Touhami, Mahmoud A. Mohsin,
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
2018 - Springer Science+Business Media | Journal of Bio- and Tribo-Corrosion
Paula Azorin, Florian Bonin, Ahmad Moukachar, Aurélie Ponceau, Sophie Vacher, Ivan Bièche, Elisabetta Marangoni, Laetitia Fuhrmann, Anne Vincent‐Salomon, Rosette Lidereau, Keltouma Driouch,
Kindlin-1, − 2, and − 3 are the three members of the Kindlin family. They are best known as regulators of integrin functions, contributing to fundamental biological processes such as cell survival, adhesion and migration. Their deregulation leads to diverse pathologies including a broad range of cancers in which both, tumor-promoting and tumor-inhibiting functions have been described. To better characterize Kindlins implication in breast cancer, in vitro experiments were performed in a series of cancer ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2018 - BioMed Central | Journal of Experimental & Clinical Cancer Research
... org/10.1109/PIMRC.2015.7343363 4Benmimoune, M., Driouch, E., Ajib, W. et. al.,: ‘ Joint transmit antenna ...
Tópico(s): Cooperative Communication and Network Coding
2018 - Institution of Engineering and Technology | Electronics Letters
Geoffrey Vargas, Mathilde Bouchet, Lamia Bouazza, Pascal Reboul, Cyril Boyault, Monica Gervais, Casina W.S. Kan, Claire Benetollo, Marie Brevet, Martine Croset, Martine Mazel, Laure Cayrefourcq, Sandra Geraci, Sophie Vacher, Francesco Pantano, Martin Filipits, Keltouma Driouch, Ivan Bièche, Michael Gnant, William Jacot, Jane E. Aubin, Martine Duterque‐Coquillaud, Catherine Alix‐Panabières, Philippe Clézardin, Edith Bonnelye,
Bone is the most common metastatic site for breast cancer. Estrogen-related-receptor alpha (ERRα) has been implicated in cancer cell invasiveness. Here, we established that ERRα promotes spontaneous metastatic dissemination of breast cancer cells from primary mammary tumors to the skeleton. We carried out cohort studies, pharmacological inhibition, gain-of-function analyses in vivo and cellular and molecular studies in vitro to identify new biomarkers in breast cancer metastases. Meta-analysis of ...
Tópico(s): HER2/EGFR in Cancer Research
2018 - Springer Nature | Oncogene
Florian Bonin, Karim Taouis, Paula Azorin, Ambre Petitalot, Zakia Tariq, Sébastien Nola, Nadège Karine Bouteille, Sandrine Tury, Sophie Vacher, Ivan Bièche, Khadija Aït Raïs, Gaëlle Pierron, Laetitia Fuhrmann, Anne Vincent‐Salomon, Étienne Formstecher, Jacques Camonis, Rosette Lidereau, François Lallemand, Keltouma Driouch,
The WW domain-containing oxidoreductase (WWOX) gene, frequently altered in breast cancer, encodes a tumor suppressor whose function is mediated through its interactions with cancer-related proteins, such as the pro-apoptotic protein p73α. To better understand the involvement of WWOX in breast tumorigenesis, we performed a yeast two-hybrid screen and co-immunoprecipitation assays to identify novel partners of this protein. We characterized the vesicular overexpressed in cancer pro-survival protein ...
Tópico(s): Peptidase Inhibition and Analysis
2018 - BioMed Central | BMC Biology
Ismael Driouch, Hassan Chatei,
Tópico(s): Fluid Dynamics and Turbulent Flows
2017 - Springer Science+Business Media | The European Physical Journal D
Rami Hamdi, Elmahdi Driouch, Wessam Ajib,
This paper investigates the downlink of a single-cell base station (BS) equipped with a large-scale antenna array system while considering a non-negligible transmit circuit power consumption. This consumption involves that activating all RF chains does not always necessarily achieve the maximum sum-rate when the total BS transmit power is limited. This paper formulates a sum-rate maximization problem when a low complexity linear precoder, such as conjugate beamforming or zero forcing beamforming, ...
Tópico(s): Cooperative Communication and Network Coding
2016 - Institute of Electrical and Electronics Engineers | IEEE Access
Mohammad Kilzi, Michel Grégoire, Valérie Bosse, Mathieu Benoît, Youssef Driouch, Michel de Saint Blanquat, Pierre Debat,
The origin and evolution of ultramafic (UM), mafic (M) and intermediate rocks emplaced within the metamorphic and anatectic series of the middle crust of the Variscan segment of the Pyrenees are defined in the light of new isotopic data U–Pb zircon ages, and Sr, Nd isotopic ratios. In the Gavarnie–Heas dome (central Pyrenees), ultramafic, mafic and intermediate rocks form three massifs several kilometers in size emplaced within the anatectic series: (i) the Gloriettes massif, which mostly consists of ...
Tópico(s): earthquake and tectonic studies
2015 - Elsevier BV | Comptes Rendus Géoscience
Ahmed Ntarmouchant, Hafid Smaïli, Telmo Bento dos Santos, Mohamed Dahire, K. Sabri, Luísa Ribeiro, Youssef Driouch, Renata Santos, Rosa María Calvo de Anta,
The Azrou-Khénifra basin, located in the SE sector of the Moroccan Central Hercynian Massif of the Western Meseta of Morocco comprises volcanic and volcanoclastic rocks where two magmatic sequences can be distinguished: i) the Dhar Lahmar Sequence, composed of Upper Visean basaltic lava flows and pyroclastic deposits; and ii) the Kef Al Asri Sequence, composed of Visean – Serpukhovian intermediate to acid rocks. A continuous spatial and temporal evolution between the two volcano-sedimentary sequences ...
Tópico(s): earthquake and tectonic studies
2015 - Elsevier BV | Journal of African Earth Sciences
Laia Querol Cano, Derek N. Lavery, Soraya Sin, Emma Spanjaard, Greg N. Brooke, Jessica Tilman, Ahmed Abroaf, Luke Gaughan, Craig Robson, Rakesh Heer, Francesco Mauri, Johan de Rooij, Keltouma Driouch, Charlotte L. Bevan,
Prostate cancer is an androgen receptor (AR)‐dependent malignancy at initiation and progression, therefore hormone therapy is the primary line of systemic treatment. Despite initial disease regression, tumours inevitably recur and progress to an advanced castration‐resistant state a major feature of which is metastasis to the bone. Up‐regulation of AR cofactors and chaperones that overcome low hormone conditions to maintain basal AR activity has been postulated as a mechanism of therapy relapse. ...
Tópico(s): Ubiquitin and proteasome pathways
2014 - Elsevier BV | Molecular Oncology
Cognitive radio is regarded as the ideal candidate for enhancing the efficiency of spectrum usage for next-generation wireless systems. In fact, this emerging technology allows unlicensed cognitive users to transmit over frequency bands that are initially owned by license holders through the use of dynamic spectrum sharing. In this paper, we propose a novel algorithm that efficiently solves the problem of spectrum sharing and user scheduling in a cognitive downlink multi-input-multi-output system ( ...
Tópico(s): Advanced Wireless Network Optimization
2013 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Vehicular Technology