... Verlagshandlung Dietrich Reimer (Ernst Vohsen) Berlin:. Ngaundere Sheet: E3. 1:300 000 Stamped GSGS Map Room, WO, ...
0000 - Gale Group | NCCO EuropeAfrica
Karthik V Gottemukkala, Jakub Chrustowicz, Dawafuti Sherpa, Sara Sepic, Duc Tung Vu, Özge Karayel, E. Papadopoulou, Annette Groß, Kenji Schorpp, Susanne von Gronau, Kamyar Hadian, Peter J. Murray, Matthias Mann, Brenda A. Schulman, Arno F. Alpi,
The yeast glucose-induced degradation-deficient (GID) E3 ubiquitin ligase forms a suite of complexes with interchangeable receptors that selectively recruit N-terminal degron motifs of metabolic enzyme substrates. The orthologous higher eukaryotic C-terminal to LisH (CTLH) E3 complex has been proposed to also recognize substrates ... WDR26, which promotes the formation of supramolecular CTLH E3 assemblies. Here, we discover that human WDR26 binds ... mononucleotide-adenylyltransferase 1 (NMNAT1) and mediates its CTLH E3-dependent ubiquitylation independently of canonical GID/CTLH E3- ...
Tópico(s): Peptidase Inhibition and Analysis
2024 - Elsevier BV | Molecular Cell
Directory of Open Access Journals (DOAJ)
... Verlagshandlung Dietrich Reimer (Ernst Vohsen) Berlin:. Ngaundere Sheet: E3. 1:300 000 Stamped GSGS Map Room, WO, ...
0000 - Gale Group | NCCO EuropeAfrica
Su Hyoun Lee, Yun Ju Lee, Sungyeon Jung, Kwang Chul Chung,
... in the SKP1–Cullin–1–F-box (SCF) E3 ligase complex that facilitates the ubiquitination of substrates. ... this study, we identified FBXO7 as a novel E3 ligase for SIRT7 that negatively regulates intracellular SIRT7 ... linked FBXO7-R498X mutant, which reduced SCF-dependent E3 ligase activity, did not affect the stability of ... in the SKP1–Cullin–1–F-box (SCF) E3 ligase complex that facilitates the ubiquitination of substrates. ... this study, we identified FBXO7 as a novel E3 ligase for SIRT7 that negatively regulates intracellular SIRT7 ...
Tópico(s): Calcium signaling and nucleotide metabolism
2023 - Elsevier BV | Journal of Biological Chemistry
IEEE Xplore
... German Maps on Various Scales. Lake Rukwa Sheet E3 [GEC] GSGS 3026. 1: 300 000 Production: Compiled/ ...
0000 - Gale Group | NCCO EuropeAfrica
Marina N. Iriondo, Asier Etxaniz, Yaiza R. Varela, Uxue Ballesteros, Melisa Lázaro, Mikel Valle, Dorotea Fracchiolla, Sascha Martens, L. Ruth Montes, Félix M. Goñi, Alicia Alonso,
... GABARAP conjugation systems. The ATG12–ATG5-ATG16L1 or E3-like complex (E3 for short) acts as a ubiquitin-like E3 enzyme, promoting LC3/GABARAP proteins anchoring to the ... same conditions, and also because the full human E3 was only recently available. In the present study, ... been reconstituted in the presence and absence of E3, and the mechanisms by which E3 and LC3/GABARAP proteins participate in vesicle tethering ... fusion have been investigated. In the absence of E3, GABARAP and GABARAPL1 showed the highest activities. Differences ...
Tópico(s): Calcium signaling and nucleotide metabolism
2023 - Springer Nature | Cellular and Molecular Life Sciences
IEEE Xplore
... German Maps on Various Scales. Lake Rukwa Sheet E3 [GEC] GSGS 3026. 1: 300 000 Production: Compiled/ ...
0000 - Gale Group | NCCO EuropeAfrica
Pia Maria van gen Hassend, Aparna Pottikkadavath, Carolyn Delto, Monika Kuhn, Michelle Endres, Lars Schönemann, Hermann Schindelin,
... 1 homology motif) complex is a multisubunit RING E3 ligase with poorly defined substrate specificity and flexible ... that differ in quaternary structure, thereby allowing the E3 ligase to presumably target different substrates. With the ... are critical to establish the scaffold of this E3 ligase. We demonstrate that the ability of muskelin ... 1 homology motif) complex is a multisubunit RING E3 ligase with poorly defined substrate specificity and flexible ... that differ in quaternary structure, thereby allowing the E3 ligase to presumably target different substrates. With the ...
Tópico(s): Glycosylation and Glycoproteins Research
2023 - Elsevier BV | Journal of Biological Chemistry
... German Maps on Various Scales. Lake Rukwa Sheet E3 GSGS 3026. 1: 300 000 Production: Compiled/Produced: ...
0000 - Gale Group | NCCO EuropeAfrica
Daniel Salas‐Lloret, Nicolette S. Jansen, Easa Nagamalleswari, Coen van der Meulen, Ekaterina Gracheva, Arnoud H. de Ru, H. Anne Marie Otte, Peter A. van Veelen, Andrea Pichler, Joachim Goedhart, Alfred C.O. Vertegaal, Román González‐Prieto,
... conjugation cascades consist of dedicated E1, E2, and E3 enzymes with E3s providing substrate specificity. Mass spectrometry-based approaches have ... 3 target proteins. The limited number of SUMO E3s provides the unique opportunity to systematically study E3 substrate wiring. We developed SUMO-activated target traps ( ... and systematically identified substrates for eight different SUMO E3s, PIAS1, PIAS2, PIAS3, PIAS4, NSMCE2, ZNF451, LAZSUL (ZNF451- ... SUMO1 and 961 SUMO2/3 targets in an E3-specific manner. We found pronounced E3 substrate preference. ...
Tópico(s): Glycosylation and Glycoproteins Research
2023 - American Association for the Advancement of Science | Science Advances
... German Maps on Various Scales. Lake Rukwa Sheet E3 GSGS 3026. 1: 300 000 Production: Compiled/Produced: ...
0000 - Gale Group | NCCO EuropeAfrica
Orhi Barroso‐Gomila, Laura Merino‐Cacho, Veronica Muratore, Coralia Pérez, Vincenzo Taibi, Elena Maspero, Mikel Azkargorta, Ibón Iloro, Fredrik Trulsson, Alfred C.O. Vertegaal, Ugo Mayor, Félix Elortza, Simona Polo, Rosa Barrio, James D. Sutherland,
Hundreds of E3 ligases play a critical role in recognizing specific substrates for modification by ubiquitin (Ub). Separating genuine targets of E3s from E3-interactors remains a challenge. We present BioE3, a powerful approach for matching substrates to Ub E3 ligases of interest. Using BirA-E3 ligase fusions and bioUb, site-specific biotinylation of Ub-modified substrates of particular E3s facilitates proteomic identification. We show that BioE3 identifies ... known and new targets of two RING-type E3 ligases: RNF4 (DNA damage response, PML bodies), and ...
Tópico(s): Autophagy in Disease and Therapy
2023 - Nature Portfolio | Nature Communications
National Library of Medicine (NCBI)
Andrew Robson, Eve Peasnall, Sheila Keating, Jonathan Spence, Andrew Norfolk and Sam Coates, David Downing, Stella Shamoon, Helen Studd, Robert Cole, Giles Whittell and James Doran, Catherine Riley, Andrew Pierce, Harmann Hesse, Daphne Metland, Jeremy Whittie, Patricia Davies, Adam Sherwin Media Reporter, Sarah Potter, Gary Duncan, Simon Barnes, Gary Neville, Philip Ridd, Paul Hoggart, Mark Souster, Nigel Hawkes and Alice Miles, Anne Adams, Richard Hobson, Sam Lister, Claire McDonald and Sarah Butler, Martin Richards, Gwyneth Paltrow, Ivo Tennant, Isabel Conway and Roger Boyes, Susanne Doyle, Michael Evans Defence Editor, Philip Howard, Hannah Betts, Ian Cobain, Hilary Finch, David Chater, Jeremy Kingston, Michael Binyon, Richard Quin, Shamim Sarlf, Clive Davis, Alison Kervin, Anne Gatti, Elizabeth Judge, Gabrielle Starkey, E. Jane Dickson, I. A. Olson, GS, George Henry Pearce, Andrew Norfolk, Oliver Wright and Elizabeth Judge, Kevin Eason, Mark Atherton and Richard Miles, Geoff Brown, Ben Elton, Sue Connolly Sports Picture Editor, Clare Stewart, Thunderer, Giles Coren, Andrew Norfolk, Glyn Brown, Antonia Senior, Ben Webster Transport Correspondent, Noel Falconer, Pat Gibson, Mark Griffiths, John Clarke, Steve Keenan, Thrasy Petropoulos, Michael Horsnell and Graham Keeley, Stewart Tendler Crime Correspondent, Katherine Swift, Dominic Walsh, Ollie Alderson, Russell Kempson and Oliver Kay, Jerome Boyd Maunsell, Debra Craine, Mike Pattenden, Greg Watts, Libby Purves, MM, Candida Crewe, Jo Morris, Michael Daley, Alan Hamilton, Robin Young, Stephen Farrell, Andy Stephens, Jenny MacArthur, VB, Graham Keeley, Helen Rumbelow, David Roffe, Matt Dickinson Chief Football Correspondent, Tim Teeman, David Charter, Nicholas Wapshott, Caroline Merrell Banking Correspondent, Clive Mathieson Telecoms Correspondent, Derwent May, Angela Jameson, Tamaron, Christopher Jones, Russell Kempson, Paula Hawkins, Emma Mahony, Vanora Bennett, Nigel Williamson, Ed Potton, Oliver Kay, Stephen Anderton, Amber Cowan, Stevie Chick, Mark Atherton, Jane Wheatley, Michael Theodoulou, Rick Broadbent, Stephen Burgen, Mark Henderson Science Correspondent, Geoffrey Wansell, Milo Keynes, Ann Treneman, Simon de Bruxelles, Gordon Blackwell, Geoffrey Dean, John Hopkins Golf Correspondent, Rob Wright, IH, Sarah Turner, Neil Harman Tennis Correspondent, Raymond Keene, Adam Sage, Ian Edgar, Lewis Smith, Philip J. Duke, John Brown, Matt Dickinson, Lucy Pinney, James Allcock, Tom Wright, Greg Hurst Parliamentary Correspondent, Brian Birch, Neville Scott, Caroline Merrell, Russell Hotten, Helen Nugent, Christopher Martin-Jenkins Chief Cricket Correspondent, Rob MacRory, Roger Boyes, David Mattin, Helen Rumbelow and Alexandra Frean, Nick Hasell, Chloë Bryan-Brown, Maggie Anderson, Richard Beeston Diplomatic Editor and Ross Dunn, David Hands Rugby Correspondent, James Collard, Paul Simons, Colin Pressdee, Steve Jelbert, Nick Szczepanik, John Goodbody, Dominic Kennedy, Dearbáil Jordan, Anne Ashworth, James Doran, Giles Whittell, Katty Kay, Jane Shilling, Ian Johns, Clive Field, Mike Berry, Matthew Parris, Christopher Hawtree, Fay Weldon, George Caulkin, Chris McGrath, Doug McKinlay, Gordon Lishman, Michael Austin, Alan Lee, Ingrid Mansell, NW, Walter Gammie, Anthony Loyd, DC, Ben MacIntyre, Sally Patten and Dominic Walsh, Lea Paterson Economics Editor, Bess Twiston Davies, Matthew Redhead, David Hutcheon, David Charter Chief Political Correspondent, Michael Dynes, Alison Gibson, Richard Miles, John Naish, Geoffrey Rowell, Simon Jenkins, Graham Searjeant, Annabelle Thorpe, Martin Waller, Kieran Falconer, Carl Mortished International Business Editor, Laura Peek, Mike Brewer Football flutter, Valerie Elliott Consumer Editor and Robin Young, Angus Batey, Jonathan Meades, Dr Thomas Stuttaford, Jill Crawshaw, Hugh Thompson, Bill Edgar, Jack Bailey, Tom Chesshyre, Nick Seddon, Paul Connolly, Valerie Grove, Tom Baldwin Deputy Political Editor, John Alderman, Fiona Beckett, Brian Hale, Julian Ryall, RM, Robert Whymant, Sally Patten, Cath Urquhart Travel Editor, Brian Clarke Fishing Correspondent, Josie Barnard, Roger Fokerd, Matf Seaton, Patience Wheatcroft, Christopher Irvine, Anthony Saunders, Jayne Dowle,
... Display Advertising Items The Times London Property Bow E3 Barratt Multiple Display Advertising Items Kuhn & Partner Brief ...
2002 - Gale Group | TDA
Yunhua Peng, Jing Liu, Hiroyuki Inuzuka, Wenyi Wei,
... ubiquitin-conjugating enzyme E2, and the ubiquitin ligase E3, and the transfer of ubiquitin onto the lysine ... Full Text PDF PubMed Scopus (701) Google Scholar). E3 ubiquitin ligases dictate the specificity of the ubiquitination ... Google Scholar). The human genome contains over 600 E3 ligases, of which only a few have well- ... three functional modalities, including a POI ligand, an E3 ligase ligand, and a chemical linker that bridges ... 171-179Crossref PubMed Scopus (73) Google Scholar). Various E3 ligases have been employed for PROTAC development, such ...
Tópico(s): Peptidase Inhibition and Analysis
2023 - Elsevier BV | Journal of Biological Chemistry
National Library of Medicine (NCBI)
... leaf (t.-p.) unsigned, A-E4 (E2 numbered E3: E4 blank) Book-plate of Henry Stevens of ...
0000 - Gale Group | Sabin
Haixia Zhuang, Ying Ren, Chenyu Mao, Yueya Zhong, Zubin Zhang, Biyin Cao, Yuming Zhang, Jinqi Huang, Guoqiang Xu, Zhenqian Huang, Yujia Xu, Xinliang Mao,
... in an in vitro ubiquitination system without other E3 ligases. Consistently, reexpression of RNF6 ablates drug-induced ... our results reveal that RNF6 is a RING E3 ligase that undergoes auto-ubiquitination, which could be ... in an in vitro ubiquitination system without other E3 ligases. Consistently, reexpression of RNF6 ablates drug-induced ... our results reveal that RNF6 is a RING E3 ligase that undergoes auto-ubiquitination, which could be ... that auto-ubiquitination is a characteristic of RING E3 ligases, whether RNF6 could undergo auto-ubiquitination and ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2022 - Elsevier BV | Journal of Biological Chemistry
National Library of Medicine (NCBI)
Andrew Robson, Eve Peasnall, Simon Barnes Chief Sports Writer, Lucy Alexander, Phil Yates, John McNamara, Mike Theodoulou, Cath Urquhart, David Adams, Stella Shamoon, Robert Dawson Scott, Frances Charlesworth, Robert Hands, Rupert Mellor, Catherine Riley, Andrew Pierce, Lexa Doig, James Frampton, Patricia Davies, Ivo Tennant Junior Cricket, Adam Sherwin Media Reporter, Maggie Alderson, Jane MacQuitty, Simon Barnes, Mary-Louise O'Callaghan, Matthew Crockatt, John Phillips and Dragan Petrovic, John Hartley, SD, Paul Hoggart, Amy Barry, David Rhys Jones, Martin Richards, John Mulvey, K. Brewin, Michael Evans Defence Editor, Philip Howard, Tara Holmes, David Chater, Aditi Sharma, Michael Binyon, Paul Downham, James Bone, Ian Watson, Jeremy Kingston, Nic Hopkins, Rachel Campbell-Johnston, Alison Kervin, Clive Davis, Anne Gatti, Michael J. Gee, Chairman, Bill Bond, Elizabeth Judge, Gabrielle Starkey, Diana Rau, Carl Mortished, GS, Richard Eaton, Ian Kelly, Martin Aston, Sam Marlowe, Patrick Barkham, Julian Bleach, James Eve, Peter Barlow, Geoff Brown, Russell Jenkins and Ian Cobain, Clare Stewart, Thunderer, Giles Coren, Viscount Thurso, Sandra Lawrence, Antonia Senior, Mark Griffiths, Pat Gibson, DH, Stephen McClarence, Jamie Kennedy, Hilary Rose, Donald Hutera, Steve Keenan, Katherine Swift, David Edgington, Anthony Browne, Dominic Walsh, Steve Bird, Ruth Gledhill, Ronan Keating, Shirley English, Susan Lynch, Jill Dupleix, Tim Reid, Geoff Buckley, Jeanette Winterson, Fiona Berry, Ruth Gledhill Religion Correspondent, Michael Mulvihill, Libby Purves, Richard Ford Home Correspondent, Jo Morris, Johnny Ball, Alan Hamilton, Oliver Wright, Robin Young, Stephen Farrell, Nicholas Roe, CD, Candida Crewe, Jenny MacArthur, Nick Wyke, Marcus Williams, Peter Nichols, Phil Gordon, John Latham, Judy Flinn, Nicola Johnson, Vanda Carson, Chris Johnston, Roy Strong, Hannah Hennessy and Vanda Carson, Ben Fogle, Neville Teller, Tim Teeman, Patience Wheatcroft Business Editor, Caroline Merrell Banking Correspondent, Derwent May, James Urquhart, Angela Jameson, Ivan Hewett, JJ, Russell Kempson, Paula Hawkins, Nigel Williamson, Daniel McGrory, Ed Potton, Oliver Kay, Claire Bowman, Stephen Anderton, Amber Cowan, Sharon O'Connell, M. Hammerton, Stevie Chick, Leslie C. De Gruchy, Mark Atherton, PC, Chris Power, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Hannah Hennessy, Sarah Turner, David Stenhouse, Dan Sabbagh Telecoms Correspondent, Raymond Keene, Adam Sage, Matthew Pryor, Elizabeth Judge and Sally Patten, Cheryl Taylor, Lucy Pinney, Mark Solon, James Allcock, Xan Rice, Caroline Merrell, Alice Sebold, Cathy Harris, Russell Hotten, Rob Chapman, Barry J. Lennox, Richard Owen, Anthony Browne Environment Editor, Helen Nugent, Christopher Martin-Jenkins Chief Cricket Correspondent, Sudi Pigott, Clem Cecil, Oliver August, Nick Hasell, Iain Wilton, James Collard, Colin Pressdee, Anne Ashworth, John Goodbody, Brian Case, Gabriella Gamini South America Correspondent, Peter Dingley, Ian Johns, Craig Lord, Mel Webb, Mike Berry, Maureen Waller, Deborah King, Matthew Parris, Mike Rosewell, Christopher Hawtree, Sue Hepworth, Chris McGrath, Tim Wapshott, Russell Jenkins, Glen Owen Education Correspondent, NW, Alan Lee, Derek Dainton, Iain Finlayson, Rosemary Cook, DC, Fiona Hook, Matthew Redhead, Alison Gibson, Brian Briscoe, Richard Miles, John Naish, Geoffrey Rowell, Lea Paterson, Simon Jenkins, Graham Searjeant, Martin Waller, Kieran Falconer, Michael Horsnell, Lottie Moggach, James Jackson, Emma Hartley, Nigel Hawkes Health Editor, Laura Peek, Sarah Butler, Angus Batey, Benedict Nightingale, Jonathan Meades, Melissa Kite and Greg Hurst, Dr Thomas Stuttaford, Jill Crawshaw, Hugh Thompson, Stephen Dalton, Graham Norwood, David Powell, Paul Connolly, George Edwards, Tom Chesshyre, James Christopher, Abigail Rayner, David Easter, Chris King, Allan Hall, Edward Gorman Sailing Correspondent, Jenny Davey, Chlo? Bryan-Brown, David Robertson, Patience Wheatcroft, Nigel Hawkes, Health Editor, Christopher Irvine, Susan Emmett, David Lister Ireland Correspondent,
... What's Important Entertainments Theatre Kayassine Victoria Park, E3 Proms BBC SO/Davis Albert Hall/Radio 3 ...
2002 - Gale Group | TDA
Caiyan Gan, Yinmei Zhang, Fei Liang, Xuemin Guo, Zhixiong Zhong,
... which generate six genotypes, viz, E2/E2, E2/E3, E3/E3, E3/E4, E4/E4, and E2/E4. APOE polymorphisms ... 747), and liver (8.7%, 65/747) cancers. E3/E3 was the most frequent genotype, and ɛ3 was the greatest allele frequency in our study population. The frequencies of the E3/E3, E3/E4, E2/E3, E2/E4, E4/E4, and ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2022 - BioMed Central | World Journal of Surgical Oncology
Andrew Robson, Marion McGilvary, Simon Barnes Chief Sports Writer, Christopher Pringle, Jon Ashworth, A. Peter Fawcett, David Adams, Joanna Hunter, Catherine Philip, Andrew Pierce, James Moore, Sarah Potter, Frances Gibb Legal Editor, Simon Barnes, Paul Hoggart, Edwin Lichtenstein, Richard Kauntze, Ivo Tennant, Thomas Whitell, Philip Howard, Ian Cobain, Hilary Finch, Jeremy Kingston, James Bone, Nic Hopkins, Alison Kervin, Alexandra Frean Social Affairs Correspondent, Carl Mortished, Patrick Kidd, Jeremy Whittle, Nigel Hawkes and Mark Henderson, Raymond Snoddy, Cliff Redman, Antonia Senior, Anthony Jay, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, Mrs Moneybags, Anne Spackman Property Editor, Cornelius Lysaght, Stewart Tendler Crime Correspondent, Anthony Browne, James Doran Wall Street Correspondent, Francis P. Xavier, Norman Harris, Tim Reid, Angela Jameson Industrial Correspondent, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Stephen Farrell, Jenny MacArthur, Gerald Mortimer, James Fielding, Roland Watson, Malika Browne, Charles Bremner, Emma Nicholson, Michael Pilgrim, Adam Sage and Lewis Smith, Nicholas Wapshott, Mark Court, Caroline Merrell Banking Correspondent, Angela Jameson, Dan Sabbagh and Nic Hopkins, Paula Hawkins, Nigel Williamson, Tony Halpin Education Editor, Daniel McGrory, Nicole Swengley, John Clegg, Lisa Armstrong, Tom Baldwin, John Hopkins, Ian Adcock, Simon de Bruxelles, John Hopkins Golf Correspondent, Rob Wright, Geoffrey Dean, Jill Sherman and Christine Buckley, Hannah Hennessy, Katie Sutton, Gabriel Rozenberg, David Powell Athletics Correspondent, Tony Noakes, Raymond Keene, Lewis Smith, Thrasy Petropoulous, Christine Buckley Industrial Editor, Tom Mangold, Marcus Binney Architecture Correspondent, Chris Campling, Bronwen Maddox, Russell Hotten, Richard Owen, Andrew Anderson, Christopher Martin-Jenkins Chief Cricket Correspondent, Roger Boyes, Stewart Tendler, Melissa Kite, Greg Hurst and Arabella Newnham, Dalya Alberge, David Hands Rugby Correspondent, Paul Simons, Ben Webster Transport Correspondent and Tom Chesshyre, Mike Mulvihill, Nick Szczepanik, Philip Webster Political Editor, Katty Kay, Robin Kempster, Brian MacArthur, Tim Hames, Ian Johns, Lisa Armstrong Fashion Editor and Emily Davies, Craig Lord, Andrew Dennis, Kevin McCarra, Graham Searjeant Financial Editor, M. A. Bearman, Hatch End, Middlesex, Chris McGrath, Caitlin Moran, Michael Austin, Mark Court Health Industries Correspondent, Peter Riddell, Lea Paterson Economics Editor, Robin Martin-Jenkins, Jeremy Hart, Tony Dawe, Richard Beeston, David Charter Chief Political Correspondent, Jack Malvern Arts Reporter, David Sinclair, Simon Jenkins, Lea Paterson, Martin S. Alexander, S. C. Smith, Michael Horsnell, Lisa Verrico, Stuart Birch, Dr Thomas Stuttaford, Stamp, Stephen Dalton, Penny Hunter Symon, Alan Lee Racing Correspondent, Paul Barstow, Sally Patten, R. T. Oerton, Jan Raath, Jenny Davey, David Robertson, Sally Patten Retail Correspondent, Robin Shepherd, Patience Wheatcroft, Christopher Irvine, Damian Barr, Susan Emmett,
... Conversion near Bow Zone 2-3 Schoolbell Mews, E3: a one-bed grouond floor apartment In a ...
2002 - Gale Group | TDA
MuChun Tsai, Wissam Osman, J. Adair, Rabab ElMergawy, Lexie Chafin, Finny Johns, Daniela Farkas, Ajit Elhance, J.D. Londino, Rama K. Mallampalli,
... first identified that the Skp-Cullin-F box E3 ligase subunit, FBXO45, binds to IFNLR1. We demonstrate ... first identified that the Skp-Cullin-F box E3 ligase subunit, FBXO45, binds to IFNLR1. We demonstrate ... actions of E1-activating, E2-conjugating enzymes, and E3-ubiquitin ligases, are central to intracellular protein degradation. ... PubMed Scopus (7027) Google Scholar). Of the many E3 ligases, the understanding of Skp-Cullin1-F- box ( ... 17Deshaies R.J. Joazeiro C.A. RING domain E3 ubiquitin ligases.Annu. Rev. Biochem. 2009; 78: 399- ...
Tópico(s): interferon and immune responses
2022 - Elsevier BV | Journal of Biological Chemistry