Produção Nacional
Revisado por pares
Rodrigo Gonçalves Dias, Michelle Sabrina Moreira Silva, Núbia E. Duarte, Wladimir Bolani, Cléber R. Alves, José R. Lemos, Jeferson Luís da Silva, Patrícia Alves de Oliveira, Guilherme Barreto Alves, Edilamar Menezes de Oliveira, Cristiane S. Rocha, Júlia Daher Carneiro Marsiglia, Carlos Eduardo Negrão, Eduardo Moacyr Krieger, José Eduardo Krieger, Alexandre C. Pereira,
Peripheral blood cells are an accessible environment in which to visualize exercise-induced alterations in global gene expression patterns. We aimed to identify a peripheral blood mononuclear cell (PBMC) signature represented by alterations in gene expression, in response to a standardized endurance exercise training protocol. In addition, we searched for molecular classifiers of the variability in oxygen uptake (V̇o 2 ). Healthy untrained policemen recruits ( n = 13, 25 ± 3 yr) were selected. Peak V̇o 2 (measured ...
Tópico(s): Exercise and Physiological Responses
2014 - American Physical Society | Physiological Genomics
Produção Nacional
Revisado por pares
Jan B. Bartholomeu, Andréa Somolanji Vanzelli, Natale Rolim, Julio Cesar Batista Ferreira, Luiz Roberto Grassmann Bechara, Leonardo Y. Tanaka, Kaleizu Teodoro Rosa, Márcia M. Alves, Alessandra Medeiros, Katt Coelho Mattos, Marcele A. Coelho, Maria Cláudia Irigoyen, Eduardo Moacyr Krieger, José Eduardo Krieger, Carlos Eduardo Negrão, P. R. Ramires, Sílvia Guatimosim, Patrı́cia C. Brum,
beta-blockers, as class, improve cardiac function and survival in heart failure (HF). However, the molecular mechanisms underlying these beneficial effects remain elusive. In the present study, metoprolol and carvedilol were used in doses that display comparable heart rate reduction to assess their beneficial effects in a genetic model of sympathetic hyperactivity-induced HF (alpha(2A)/alpha(2C)-ARKO mice). Five month-old HF mice were randomly assigned to receive either saline, metoprolol or carvedilol ...
Tópico(s): Heart Failure Treatment and Management
2008 - Elsevier BV | Journal of Molecular and Cellular Cardiology
Produção Nacional
Revisado por pares
Natale Rolim, Alessandra Medeiros, Kaleizu Teodoro Rosa, Katt Coelho Mattos, Maria Cláudia Irigoyen, Eduardo Moacyr Krieger, José Eduardo Krieger, Carlos Eduardo Negrão, Patrı́cia C. Brum,
The molecular basis of the beneficial effects associated with exercise training (ET) on overall ventricular function (VF) in heart failure (HF) remains unclear. We investigated potential Ca(2+) handling abnormalities and whether ET would improve VF of mice lacking alpha(2A)- and alpha(2C)-adrenoceptors (alpha(2A)/alpha(2C)ARKO) that have sympathetic hyperactivity-induced HF. A cohort of male wild-type (WT) and congenic alpha(2A)/alpha(2C)ARKO mice in a C57BL/J genetic background (5-7 mo of age) was randomly ...
Tópico(s): Ion channel regulation and function
2007 - American Physical Society | Physiological Genomics
Produção Nacional
Revisado por pares
Alessandra Medeiros, Natale Rolim, Rodrigo S. F. Oliveira, Kaleizu Teodoro Rosa, Katt Coelho Mattos, Dulce Elena Casarini, Maria Cláudia Irigoyen, Eduardo Moacyr Krieger, José Eduardo Krieger, Carlos Eduardo Negrão, Patrı́cia C. Brum,
Exercise training (ET) is a coadjuvant therapy in preventive cardiology. It delays cardiac dysfunction and exercise intolerance in heart failure (HF); however, the molecular mechanisms underlying its cardioprotection are poorly understood. We tested the hypothesis that ET would prevent Ca(2+) handling abnormalities and ventricular dysfunction in sympathetic hyperactivity-induced HF mice. A cohort of male wild-type (WT) and congenic alpha(2A)/alpha(2C)-adrenoceptor knockout (alpha(2A)/alpha(2C)ARKO) ...
Tópico(s): Cardiovascular Effects of Exercise
2007 - American Physiological Society | Journal of Applied Physiology
Produção Nacional
Revisado por pares
Mateus Camaroti Laterza, Luciana Diniz Nagem Janot de Matos, Ivani C. Trombetta, Ana Maria W. Braga, Fabiana Roveda, Maria Janieire de Nazaré Nunes Alves, Eduardo Moacyr Krieger, Carlos Eduardo Negrão, Maria Urbana Pinto Brandão Rondon,
The effects of exercise training on baroreflex control of sympathetic nerve activity in human hypertension are unknown. We hypothesized that exercise training would improve baroreflex control of muscle sympathetic nerve activity (MSNA) and heart rate (HR) in patients with hypertension and that exercise training would reduce MSNA and blood pressure (BP) in hypertensive patients. Twenty never-treated hypertensive patients were randomly divided into 2 groups: exercise-trained (n=11; age: 46±2 years) and ...
Tópico(s): Cardiac Health and Mental Health
2007 - Lippincott Williams & Wilkins | Hypertension
Produção Nacional
Revisado por pares
Fabiana Roveda, Holly R. Middlekauff, Maria Urbana Pinto Brandão Rondon, Soraya F. Reis, Márcio Gerhardt Soeiro‐de‐Souza, Luciano Nastari, Antônio Carlos Pereira Barretto, Eduardo Moacyr Krieger, Carlos Eduardo Negrão,
The goal of this study was to test the hypothesis that exercise training reduces resting sympathetic neural activation in patients with chronic advanced heart failure. Exercise training in heart failure has been shown to be beneficial, but its mechanisms of benefit remain unknown. Sixteen New York Heart Association class II to III heart failure patients, age 35 to 60 years, ejection fraction ≤40% were divided into two groups: 1) exercise-trained (n = 7), and 2) sedentary control (n = 9). A normal control ...
Tópico(s): Heart Failure Treatment and Management
2003 - Elsevier BV | Journal of the American College of Cardiology
Produção Nacional
Revisado por pares
Maria Urbana Pinto Brandão Rondon, Maria Janieire N.N. Alves, Ana Braga, Otávio Augusto De Paula Mendes Teixeira, Antônio Carlos Pereira Barretto, Eduardo Moacyr Krieger, Carlos Eduardo Negrão,
We sought to study: 1) the impact of hemodynamic and left ventricular function on short-term postexercise blood pressure reduction in elderly hypertensive patients; and 2) the 22-h postexercise effects on ambulatory blood pressure in elderly hypertensive patients. Although early exercise provokes postexercise blood pressure reduction, the mechanisms underlying this response are not completely understood. Besides, it is unclear whether the reduction in blood pressure after exercise lasts long enough ...
Tópico(s): Thermoregulation and physiological responses
2002 - Elsevier BV | Journal of the American College of Cardiology
Produção Nacional
Revisado por pares
Henrique Dipe de Faria, Carolina Tosin Bueno, José Eduardo Krieger, Eduardo Moacyr Krieger, Alexandre C. Pereira, Paulo Caleb Júnior Lima Santos, Eduardo Costa Figueiredo,
A novel analytical method was developed to determine 5 antihypertensive drugs of different pharmacological classes (angiotensin-converting enzyme inhibitors, calcium channel blockers, α-2 adrenergic receptor agonists, angiotensin II receptor blockers, and aldosterone receptor antagonists) and some of their metabolites in human serum. The untreated samples were directly analyzed in a column switching system using an extraction column packed with restricted access carbon nanotubes (RACNTs) in an ultra- ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2017 - Elsevier BV | Journal of Chromatography A
Produção Nacional
Revisado por pares
José Augusto Barreto‐Filho, Fernanda Marciano Consolim‐Colombo, Grazia Maria Guerra, Raúl D. Santos, Ana Paula Marte Chacra, Heno Ferreira Lopes, Sandra H. Teixeira, Tânia Leme da Rocha Martinez, José Eduardo Krieger, Eduardo Moacyr Krieger,
During hypoxia, active substances released by the endothelium play a key role in the cardiovascular and respiratory responses elicited to optimize oxygen delivery. As hypercholesterolemia is a major cause of endothelial dysfunction, it may interfere with these responses.We studied cardiovascular and ventilatory responses to acute systemic hypoxia in 14 patients with hypercholesterolemia (HC) and 13 control (CO) subjects. Oxygen saturation decreased similarly in both groups. Diastolic blood pressure ...
Tópico(s): Nitric Oxide and Endothelin Effects
2003 - Lippincott Williams & Wilkins | Arteriosclerosis Thrombosis and Vascular Biology
Produção Nacional
Revisado por pares
Linda Massako Ueno, Luciano F. Drager, Ana Clara Tude Rodrigues, Maria Urbana Pinto Brandão Rondon, Wilson Mathias, Eduardo Moacyr Krieger, Rubens Fazan, Carlos Eduardo Negrão, Geraldo Lorenzi‐Filho,
IntroductionAmong patients with congestive heart failure (CHF) both obstructive and central sleep apnea (SA) are associated with increased sympathetic activity. However, the day–night pattern of cardiac autonomic nervous system modulation in CHF patients with and without sleep apnea is unknown.Material and methodsTwenty-five CHF patients underwent polysomnography with simultaneous beat-to-beat blood pressure (Portapres), respiration and electrocardiogram monitoring. Patients were divided according ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2009 - Elsevier BV | International Journal of Cardiology
Produção Nacional
Revisado por pares
Eduardo Rondon, Maria S. Brasileiro‐Santos, Edson Duarte Moreira, Maria Urbana Pinto Brandão Rondon, Katt Coelho Mattos, Marcele A. Coelho, Gustavo José Justo da Silva, Patrı́cia C. Brum, Patrícia Fiorino, Maria Cláudia Irigoyen, Eduardo Moacyr Krieger, Holly R. Middlekauff, Carlos Eduardo Negrão,
Exercise training improves arterial baroreflex control in heart failure (HF) rabbits. However, the mechanisms involved in the amelioration of baroreflex control are unknown. We tested the hypothesis that exercise training would increase the afferent aortic depressor nerve activity (AODN) sensitivity in ischemic-induced HF rats. Twenty ischemic-induced HF rats were divided into trained (n = 11) and untrained (n = 9) groups. Nine normal control rats were also studied. Power spectral analysis of pulse interval, ...
Tópico(s): Blood Pressure and Hypertension Studies
2006 - American Physical Society | AJP Heart and Circulatory Physiology
Produção Nacional
Revisado por pares
Eduardo Moacyr Krieger, Patrı́cia C. Brum, Carlos Eduardo Negrão,
Exercise training plays an important role in the reduction of high blood pressure. In this review, we discuss the effect of distinct intensities of exercise training on the reduction of high blood pressure in spontaneously hypertensive rats (SHR). In addition, we present some hemodynamic mechanisms and associated neural controls by which exercise training attenuates hypertension in SHR. Low-intensity exercise training is more effective in reducing high blood pressure than is high-intensity exercise ...
Tópico(s): Heart Rate Variability and Autonomic Control
1999 - Lippincott Williams & Wilkins | Hypertension
Produção Nacional
Revisado por pares
Eduardo Moacyr Krieger, Gustavo José Justo da Silva, Carlos Eduardo Negrão,
Abstract: Dynamic exercise training has been recommended as an antihypertensive therapy and as a way to modify the effects of many cardiovascular risk factors (Arakawa, 1993; Arroll and Beaglehole, 1992; Kelly and McClellan, 1994: see references 1–3 in the paper). However, the mechanisms underlying the blood-pressure lowering effect of chronic exercise are still poorly understood. It has been suggested that a decrease in sympathetic tone is one of the major effects elicited by chronic exercise on ...
Tópico(s): Stress Responses and Cortisol
2001 - Wiley | Annals of the New York Academy of Sciences
Produção Nacional
Revisado por pares
Marta Helena Krieger, Edson Duarte Moreira, Edilamar Menezes de Oliveira, V L Oliveira, Eduardo Moacyr Krieger, José Eduardo Krieger,
1 Blood pressure (BP) and heart rate (HR) increase 6 and 24 h after sinoaortic baroreceptor denervation (SAD), whereas plasma renin activity (PRA) and renal renin mRNA levels remain unchanged. We postulated that a simultaneous rise in BP could offset the expected activation of renin associated with an increased renal sympathetic discharge secondary to SAD. 2 To test this hypothesis, the increase in BP associated with the onset of SAD was prevented by a continuous infusion of sodium nitroprusside (SNP; ...
Tópico(s): Regulation of Appetite and Obesity
2006 - Wiley | Clinical and Experimental Pharmacology and Physiology
Produção Nacional
Revisado por pares
Silvia B Souza, Juraci Aparecida Rocha, Marco Antonio Romeo Cuoco, Grazia Maria Guerra, Julio César Aires Ferreira‐Filho, Suellen Borile, Eduardo Moacyr Krieger, Luiz Aparecido Bortolotto, Fernanda Marciano Consolim‐Colombo,
The presence of asymptomatic left ventricular diastolic dysfunction (LVDD) in hypertensive patients can be associated with the development of cardiac events. The increase in sympathetic activity may be 1 of the mechanisms that predisposes to this outcome. In this study, we analyzed 2 hypotheses: (i) whether sympathetic activity is higher in the presence of LVDD, independent of blood pressure control and (ii) whether different classes of LVDD have a different effect on sympathetic activity. After analyzing ...
Tópico(s): Blood Pressure and Hypertension Studies
2013 - Oxford University Press | American Journal of Hypertension
Produção Nacional
Revisado por pares
Cristiano Teixeira Mostarda, Ivana C. Moraes‐Silva, Édson Dias Moreira, Alessandra Medeiros, Aline Cristina Piratello, Fernanda Marciano Consolim‐Colombo, Élia Garcia Caldini, Patrı́cia C. Brum, Eduardo Moacyr Krieger, Maria Cláudia Irigoyen,
Background Studies have shown that the autonomic dysfunction accompanied by impaired baroreflex sensitivity was associated with higher mortality. However, the influence of decreased baroreflex sensitivity on cardiac function, especially in diastolic function, is not well understood. This study evaluated the morphofunctional changes associated with baroreflex impairment induced by chronic sinoaortic denervation (SAD). Methods and Results Animals were divided into sinoaortic denervation (SAD) and control ( ...
Tópico(s): Cardiovascular and exercise physiology
2011 - Elsevier BV | Journal of Cardiac Failure
Produção Nacional
Revisado por pares
José Jayme G. De Lima, Luís Henrique Wolff Gowdak, Flávio Jota de Paula, L E Ianhez, José Antônio Franchini Ramires, Eduardo Moacyr Krieger,
We validated a strategy for diagnosis of coronary artery disease (CAD) and prediction of cardiac events in high-risk renal transplant candidates (at least one of the following: age > or =50 years, diabetes, cardiovascular disease).A diagnosis and risk assessment strategy was used in 228 renal transplant candidates to validate an algorithm. Patients underwent dipyridamole myocardial stress testing and coronary angiography and were followed up until death, renal transplantation, or cardiac events.The prevalence ...
Tópico(s): Cardiac Valve Diseases and Treatments
2010 - Lippincott Williams & Wilkins | Coronary Artery Disease
Produção Nacional
Revisado por pares
Luciano F. Drager, Luzia Diegues‐Silva, Patricia Martini Diniz, Geraldo Lorenzi‐Filho, Eduardo Moacyr Krieger, Luiz Aparecido Bortolotto,
Arterial stiffness is an independent marker of cardiovascular events. Pulse wave velocity (PWV) is a validated method to detect arterial stiffness that can be influenced by several factors including age and blood pressure. However, it is not clear whether PWV could be influenced by circadian variations. In the present study, the authors measured blood pressure and carotid‐femoral PWV measurements in 15 young healthy volunteers in 4 distinct periods: 8 am , noon, 4 pm, and 8 pm . No significant variations ...
Tópico(s): Non-Invasive Vital Sign Monitoring
2010 - Wiley | Journal of Clinical Hypertension
Produção Nacional
Revisado por pares
José Jayme G. De Lima, Luís Henrique Wolff Gowdak, Flávio Jota de Paula, Rodolfo Leite Arantes, André Luís Veiga de Oliveira, José Antônio Franchini Ramires, Luı́z Antonio Machado César, Eduardo Moacyr Krieger,
We assessed the results of a noninvasive therapeutic strategy on the long-term occurrence of cardiac events and death in a registry of patients with chronic kidney disease (CKD) and coronary artery disease (CAD).We analyzed 519 patients with CKD (56+/-9 years, 67% men, 67% whites) on maintenance hemodialysis with clinical or scintigraphic evidence of CAD by using coronary angiography.In 230 (44%) patients, coronary angiography revealed significant CAD (lumen reduction > or =70%). Subjects with significant ...
Tópico(s): Heart Failure Treatment and Management
2010 - Wolters Kluwer | Transplantation
Produção Nacional
Revisado por pares
Ana CM Andrade, Fernando Henpin Yue Cesena, Fernanda Marciano Consolim‐Colombo, Silmara Regina Coimbra, Alexandre Benjo, Eduardo Moacyr Krieger, Protásio Lemos da Luz,
To compare the metabolic, hemodynamic, autonomic, and endothelial responses to short-term red wine consumption in subjects with hypercholesterolemia or arterial hypertension, and healthy controls. Subjects with hypercholesterolemia (n=10) or arterial hypertension (n=9), or healthy controls (n=7) were given red wine (250 mL/night) for 15 days. Analyses were performed before and after red wine intake. Red wine significantly increased the plasma levels of HDL-cholesterol in the controls, but not in the ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2009 - Elsevier BV | Clinics
Valéria Costa‐Hong, Luiz Aparecido Bortolotto, Vanda Jorgetti, Fernanda Marciano Consolim‐Colombo, Eduardo Moacyr Krieger, José Jayme G. De Lima,
Chronic kidney disease (CKD) is characterized by the high prevalence of atherosclerosis. Considering that endothelial dysfunction and oxidative stress are promoters of atherosclerosis, it is of interest to verify whether the two conditions are associated in CKD patients still free of clinical cardiovascular disease (CVD).To evaluate the association between oxidative stress and endothelial function in end-stage CKD patients without clinically evident CVD.We studied 22 nondiabetic, nonsmoker CKD patients ...
Tópico(s): Thermoregulation and physiological responses
2009 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Luciano F. Drager, Linda Massako Ueno, Patrícia Silva Lessa, Carlos Eduardo Negrão, Geraldo Lorenzi‐Filho, Eduardo Moacyr Krieger,
The present study investigates the hemodynamic and autonomic regulation during sleep-awake transitions and across different sleep cycles in patients with essential hypertension.Nineteen individuals free of sleep apnea (10 normotensive and nine hypertensive matched for age, sex, and body mass index) underwent a standard polysomnography, with simultaneous electrocardiography and beat-to-beat blood pressure monitoring (Portapres). All measurements were determined while awake (before and after sleep), ...
Tópico(s): Sleep and related disorders
2009 - Lippincott Williams & Wilkins | Journal of Hypertension
Produção Nacional
Revisado por pares
Luís Henrique Wolff Gowdak, Flávio Jota de Paula, Luı́z Antonio Machado César, Eulógio Emílio Martinez Filho, Luiz E. Ianhez, Eduardo Moacyr Krieger, José Antônio Franchini Ramires, José Jayme G. De Lima,
Background Renal transplant candidates are at an increased risk for coronary artery disease (CAD), a strong predictor of cardiovascular events [major adverse coronary events (MACE)]. Coronary angiography is a costly, risky, invasive procedure. We sought to determine clinical predictors of significant CAD (stenosis ≥70%) in high-risk renal transplant candidates. Methods Clinical evaluation and coronary angiography were performed in 301 patients (57±8 years, 73% men) on hemodialysis for 32 months (median). ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2007 - Lippincott Williams & Wilkins | Coronary Artery Disease
Produção Nacional
Revisado por pares
Valéria Costa‐Hong, Vanda Jorgetti, Luís Henrique Wolff Gowdak, Rosa Maria Affonso Moysés, Eduardo Moacyr Krieger, José Jayme G. De Lima,
Background Secondary hyperparathyroidism (SHPT) and its associated abnormalities in mineral metabolism increase the risk of cardiovascular morbidity and death in chronic renal failure (CRF). The effect of parathyroidectomy (PTX) on the incidence of major cardiovascular events in CRF patients with SHPT is unknown. We tested the hypothesis that PTX reduces the incidence of cardiovascular complications and death in CRF patients with severe SHPT scheduled for PTX, comparing the outcome of patients treated or not ...
Tópico(s): Potassium and Related Disorders
2007 - Elsevier BV | Surgery
Produção Nacional
Revisado por pares
Luís Henrique Wolff Gowdak, Flávio Jota de Paula, Luı́z Antonio Machado César, Eulógio Emílio Martinez Filho, L E Ianhez, Eduardo Moacyr Krieger, José Antônio Franchini Ramires, José Jayme G. De Lima,
In renal transplant candidates (RTC), diabetes and coronary artery disease (CAD) are commonly observed. However, whether diabetes imparts a cardiovascular risk equivalent to that of CAD and whether CAD adds to the cardiovascular risk associated with diabetes is unknown.To assess the interplay between diabetes and CAD as a determinant of major adverse cardiovascular events (MACE), 288 high-risk RTC (56.4+/-8.1 years old, 72% males) underwent a comprehensive cardiovascular evaluation including coronary ...
Tópico(s): Diabetes Treatment and Management
2007 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Luís Henrique Wolff Gowdak, Rodolfo Leite Arantes, Flávio Jota de Paula, Eduardo Moacyr Krieger, José Jayme G. De Lima,
Patients with end-stage renal disease (ESRD) are at high risk for cardiovascular disease (CVD) and therefore should be treated according to ACC/AHA Guidelines. Scant data are available concerning the actual use of cardioprotective drugs in this population. The use of angiotensin-converting enzyme inhibitors (ACE-I), beta-blockers, aspirin, and statins was assessed in 271 (72% males, 66% Caucasians) high-risk ESRD patients on hemodialysis. The study population comprised 27% smokers, 95% with hypertension, ...
Tópico(s): Medication Adherence and Compliance
2007 - Taylor & Francis | Renal Failure
Produção Nacional
Revisado por pares
Pedro Paulo da Silva Soares, Catarina S. Porto, Fernando Maurício Francis Abdalla, Raquel Nitrosi de La Fuente, Édson Dias Moreira, Eduardo Moacyr Krieger, Maria Cláudia Irigoyen,
We studied heart rate (HR) responses to vagal electrical stimulation (VES) and the expression of muscarinic acetylcholine receptors (mAChRs) in the rat atria 1 day (SADa) and 20 days (SADc) after sinoaortic denervation (SAD). Arterial blood pressure (BP) was recorded in conscious, unrestrained rats and during vagal electrical stimulation of the vagus nerve. In the acute phase, SADa rats had hypertension, tachycardia, and increased blood pressure lability. In the chronic phase, heart rate and blood pressure ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2006 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
Produção Nacional
Revisado por pares
Ângela d’Avila Harthmann, Kátia De Angelis, Luciana Parente Costa Seguro, Danielle Senador, Beatriz D. Schaan, Eduardo Moacyr Krieger, Maria Cláudia Irigoyen,
We investigated the effect of exercise training on blood pressure, heart rate, and arterial baro- and chemoreflex sensitivity in diabetic rats (streptozotocin, 50 mg/kg iv). Male Wistar rats (251+/-10 g) were divided into 4 groups (n=8, each group): sedentary normotensive (SC), sedentary diabetic (SD), trained normotensive (TC), and trained diabetic (TD). Trained groups underwent exercise training on a treadmill (10 weeks). Exercise training induced resting bradycardia (340+/-5 vs. 316+/-8 bpm) and improvement ...
Tópico(s): Neuroscience of respiration and sleep
2006 - Elsevier BV | Autonomic Neuroscience
Produção Nacional
Revisado por pares
Mauricio Sendeski, Fernanda Marciano Consolim‐Colombo, Cláudia C. Leite, Marcelo Custódio Rubira, Patrícia Silva Lessa, Eduardo Moacyr Krieger,
We used microneurography to measure muscle sympathetic nerve activity (MSNA) in 25 hypertensive subjects and correlated these results with the presence or absence of signs of neurovascular compression (NVC) at the rostral ventrolateral (RVL) medulla on MRI. Subjects were divided into 3 groups based on MRI findings: NVC − , no MRI evidence of NVC (N=9); NVC+contact, image showing artery in contact but not compressing the RVL medulla (N=8); and NVC+compression, image showing arterial compression of the RVL ...
Tópico(s): Cerebral Venous Sinus Thrombosis
2006 - Lippincott Williams & Wilkins | Hypertension
Produção Nacional
Revisado por pares
Hilton Chaves, Fernando Menezes Campello de Souza, Eduardo Moacyr Krieger,
A limited reproducibility has been ascribed to 24-h ambulatory blood pressure monitoring, especially in relation to the dipper and nondipper phenomena. This study examined the reproducibility of 24-h ambulatory blood pressure monitoring in three recordings of pressure at intervals of 8–15 days in 101 study participants (73% treated hypertensive patients) residing in the city of Recife, Pernambuco, Brazil. SpaceLabs 90207 monitors were used, and the minimum number of valid measurements was 80. No ...
Tópico(s): Heart Rate Variability and Autonomic Control
2005 - Lippincott Williams & Wilkins | Blood Pressure Monitoring