From Michael Hamlyn, , By David Smith, Economics Correspondent, By Frances Gibb, Legal Affairs Correspondent, From Zoriana Pysariwsky, By David Felton, Labour Correspondent, By Julian Haviland, Political Editor, By Rodney Cowton, Thomson Prentice, By Philip Webster, Political Reporter, By Clifford Webb Motoring Correspondent, By Clifford Longley Religious Affairs Correspondent, By Geraldine Norman, Sale Room Correspondent, By Robin Young, By Craig Seton, By Rupert Morris, Barrie Clement, By John Young Agriculture Correspondent, From Peter Davenport, By Patricia Clough, By Peter Evans, Home Affairs Correspondent, By Frances Gibb Legal Affairs Correspondent, From Trevor Fishlock, Beartrap Canyon, , From Tony Duboudin, , By Henry Stanhope Diplomatic Correspondent, From Richard Owen, , Peter Ustinov, From Kenneth Fleet, , From Carol Berger, , From Jan Raath, From Alan Tomlinson, , From Roger Boyes, From Richard Wigg, From Diana Geddes, , From Nicholas Ashford, , From A Bridge Correspondent, From Christopher Walker, , From Michael Hornsby, From Moshin Ali, , From Michael Binyon, Nicholas Kenyon, David Robinson, Irving Wardle, Stephen Pettitt, Richard Owen, Miles Kington, Rowan Whimster, Gill Pyrah, Olivia Timbs, Lorraine Fraser, PHS, by Sarah Hogg, Michael Hamlyn, Edward Townsend Industrial Correspondent, David Watt, Philip Howard, HENRY PLUMB, , T. H. RICHARDSON, , MICHAEL BARLEY, , UVEDALE TRISTRAM, , PETER SEARLE, , CHARLES PEREIRA, , CHRISTOPHFR CHAVASSE, , T. A. BEETHAM, , CHRIS SMITH, , CHARLES HUNT, , JOHN MADDISON, , BLAKE, , ALAN H. PROTHEROE, , E. H. MOORE, , By Judy Redfearn, Peter Davenport, Russell Jenkins, RJ, ML, Malcolm Long, PD, Executive Editor Kenneth Fleet, By Jeremy Warner, By Derek Harris Commercial Editor, By William Kay, City Editor, By Jonathan Davis, Business Correspondent, By Judith Huntley, Commercial Property Correspondent, By Our Business Correspondent, By Derek Pain, Ken Pyne, By Bailey Morris, By Joyce Whitehead, By Paul Harrison, By Sydney Friskin, By Philip Nicksen, Michael Hornsby, By Keith Macklin, By Peter Aykroyd, By Richard Eaton, From Richard Streeton, By Srikumar Sen, By Rex Bellamy Tennis Correspondent, Schools rugby by Michael Stevenson, From Mitchell Platts, By Mandarin (Michael Phillips), Simon Barnes, By Stuart Jones Football Correspondent, Non-League football by Paul Newman, by Clifford Webb, by Peter Dear, Peter Davalle, By Ruper Morris, From Stewart Tendler, Frank Johnson,
... and Notices: Leicestershire Lieutenancy, Latest appointments. Marriages. Obituaries: Eduardo De Filippo, Mr M. Babington Smith Eminent city ...
1984 - Gale Group | TDA
Produção Nacional
Revisado por pares
Gustavo Cruz Campos, J.M. Gomes da Silva, Sophie Tarbouriech, Carlos Eduardo Pereira,
... Toulouse, FranceSearch for more papers by this authorCarlos Eduardo Pereira, Carlos Eduardo Pereira DELAE, Universidade Federal do Rio Grande do Sul, ... Toulouse, FranceSearch for more papers by this authorCarlos Eduardo Pereira, Carlos Eduardo Pereira DELAE, Universidade Federal do Rio Grande do Sul, ...
Tópico(s): Cybersecurity and Information Systems
2018 - Institution of Engineering and Technology | IET Control Theory and Applications
Produção Nacional
Revisado por pares
Edison Pignaton de Freitas, Tales Heimfarth, Carlos Eduardo Pereira, Armando Morado Ferreira, Flávio Rech Wagner, Tony Larsson,
... this author on: Oxford Academic Google Scholar Carlos Eduardo Pereira, Carlos Eduardo Pereira 2Institute of Informatics, Federal University of Rio Grande ...
Tópico(s): Context-Aware Activity Recognition Systems
2009 - Oxford University Press | The Computer Journal
Produção Nacional
Revisado por pares
Maria Cristina Pinheiro Pereira Reis-Mansur, C. Eduardo Pereira Siqueira Campos, Alane Beatriz Vermelho, Jonas Nobrega, Leonardo Pereira, Luciene Bottentuit López Balottin, Claudia Lage, Alexandre Soares Rosado, Eduardo Ricci‐Júnior, Elisabete Pereira dos Santos,
Photoprotective nanoemulsions are able to attenuate skin damage from overexposure to the sun, thus avoiding the immediate effects caused by ultraviolet radiation. The global cosmetics market understands that there is a demand and greater acceptance by consumers for formulations containing natural products compatible with the skin. Consequently, there is an increasingly need to develop such products that are safe and effective. Furthermore, there is a growing interest in nanoemulsions (NE) in the ...
Tópico(s): Olfactory and Sensory Function Studies
2020 - Elsevier BV | Arabian Journal of Chemistry
Produção Nacional
Revisado por pares
Lucas Raimundo Rauber, Letícia Sequinatto, Douglas Rodrigo Kaiser, Ildegardis Bertol, Tiago Celso Baldissera, F. C. Garagorry, André Fischer Sbrissia, Gustavo Eduardo Pereira, Cassiano Eduardo Pinto,
Natural grasslands in southern Brazil are ecosystems that are naturally adapted to grazing. Despite the productivity and ecological relevance of these ecosystems, the effects of grazing intensity on their soil quality are still underexplored. This work aimed to determine whether increasing the grazing intensity would jeopardize the soil structure in a natural highland grassland in southern Brazil. Pastures were evaluated at four pregrazing canopy heights, 0.12, 0.20, 0.28 and 0.36 m, with Andropogon ...
Tópico(s): Agroforestry and silvopastoral systems
2021 - Elsevier BV | Agriculture Ecosystems & Environment
Produção Nacional
Fábio Celestino Pereira, Carlos Eduardo Pereira,
Aiming at the use of Unmanned Aerial Vehicle (UAV) in civil construction for autonomous inspection of building pathologies, this paper discusses some implementation alternatives of image processing algorithms for the detection of cracks in building facades. These algorithms should run in an embedded computing platform installed on UAVs. Two image processing algorithms for crack detection and classification were selected and different embedded system implementations were evaluated. A version of the ...
Tópico(s): Remote Sensing and LiDAR Applications
2015 - Elsevier BV | IFAC-PapersOnLine
Produção Nacional
Revisado por pares
Adriana V. Safatle‐Ribeiro, Pedro Araújo Petersen, Dilson S. Pereira Filho, Carlos Eduardo Pereira Corbett, Joel Faintuch, Robson Kiyoshi Ishida, Paulo Sakai, Ivan Cecconello, Ulysses Ribeiro,
Tópico(s): Helicobacter pylori-related gastroenterology studies
2013 - Springer Science+Business Media | Obesity Surgery
Behzad Zahabizadeh, J. Nunes‐Pereira, Claúdia Gonçalves, Eduardo Pereira, Vítor M. C. F. Cunha,
Tópico(s): BIM and Construction Integration
2021 - Springer Science+Business Media | Materials and Structures
Sérgio Ricardo Reis Soares, Nelson Ayres Barradas de Freitas, Emanuel Pereira, Eduarda Nepomuceno, Eduardo Pereira, José Sena-Cruz,
Freshwater is an increasingly scarce resource. Its use in the production of concrete is one important contributor to its fast depletion. Alternatively, the use of seawater for reinforced concrete production, combined with the use of glass fibre reinforced polymers (GFRP) as reinforcement, may represent an interesting solution to increase concrete sustainability. The objective of this paper is to explore this promising solution through the development of concrete compositions with seawater. Additionally, ...
Tópico(s): Innovative concrete reinforcement materials
2019 - Elsevier BV | Construction and Building Materials
Produção Nacional
Revisado por pares
Carlos Demócedes Luís de França Almeida Moreira, Jonas Gabriel de Oliveira Pinheiro, Walter Ferreira da Silva-Júnior, Euzébio Guimarães Barbosa, Zênia Maria Maciel Lavra, Erick Willyame Menezes Pereira, Marília Matos Rezende, Eduardo Pereira de Azevedo, Lucindo José Quintans‐Júnior, Adriano Antunes de Souza Araújo, Jullyana de Souza Siqueira Quintans, Ádley Antonini Neves de Lima,
Hecogenin acetate (HA) is an acetylated sapogenin that has shown potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors. However, HA exhibits poor aqueous solubility, which may limit its application. This study aims to develop amorphous solid dispersions (ASD) using five hydrophilic polymers, to characterize them and to evaluate their antihyperalgesic activity. Physicochemical characterization was performed by X-Ray Diffraction (XRD), Scanning Electron Microscopy ( ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2017 - Elsevier BV | Biomedicine & Pharmacotherapy
Caroline Berchet, Tiago Cravo, Oliveira Hashiguchi, Gabriel Paolantonio, Cristián Herrera, Ece Tom, Raitzik Zonenschein, Angel Eugenio, Benitez Collan, Ana Cavalcante De Lima, Ana Claire Pimenteira Thomaz, Maya Martins, Anna Carvalho, Anna Hormes, Ariene Silva do Carmo, Camila Secundo, Carolina Palhares, Caroline Martins, Corah Prado, Dalila Tusset, Daniela Cristina de Medeiros Araújo, D. Nunes Guedes, Zanardi Dressiane, Eduardo Pereira, Fernandes Augusto, David Nilson, Eduardo Gomes, Erika Nilson, Macedo Almeida, Gisele Rodrigues da Silva, Graziela Bortolini, João Manuel R. S. Tavares, João Ameno, Karla Freitas, Kátia da Silva Wanderley, Ludimila Gomes, Dos Oliveira, Ludimyla Santos, Magali Rodrigues, Casola Cristini, Magali Kumbier, Márcia Kumbier, Márcia Marinho Da Silva, Maria Jovanovic, Melo Angelim, Marize Brasil, Marize Lima De Sousa, Holanda Biazotto, Myrian Cruz, Olívia Lucena de Medeiros, Paloma Abelin, Saldanha Marinho, Paula Fabrício Sandreschi, Rebeca Carmo De Souza Cruz, Renata S. M. Gomes, Rizoneide Soares, Santana Gomes De Oliveira, Maria Lucília dos Santos, Thais Da Costa Araújo, Vania Coutinho De Oliveira, Wendel Canuto, Teixeira Rodrigo, Freire Baeta, Paula Mendes, Renata De, Morais Souza, Ricardo Silva, Rodrigo Martins De Vargas, Antony De, Souza Lima, Tiago Lanius, Katia Audi, Maria Borges, Dos Santos, Oswaldo Gonçalves Cruz, Itamar Bento, Renata Maciel, Carlos Müller, Eduardo Fernandes Marcusso, Hugo Caruso, Nilton De Morais, Aliadne Sousa, Antônio Carlos, Rosa De Oliveira, Eliana Maria, Ribeiro Dourado, Everton Macêdo, Fernando C. Passos, C. Barros, Dobis Bernarde, Maria Oliveira Evangelista, Henrique Mansano, J Romero-Troncoso Rene, Dos Moreira, Rita Santos, Cássia De, Blenda Pereira, Martins Pantaleão, Diogo Demarchi, Marcela Alvarenga, Marizelia Moreira, Aline Nazaré Habib Guedes, André Tavares, Cristina Shimoda, Davi Iguatu, Fernanda Costa Nunes, Vinícius Torres Pinto, Katiana Santos Telefora, Costa Sousa, Letícia Maria Belarmino Gonçalo, Luis Johns, Alexandre Novachi, Anna Alves, Laura Cury, Márcio Pinheiro Maciel, Marina Mantovani, Raquel Gonçalves Salgado, Adriano Massuda, Alexandre Lemgruber, André Médici, Daniel Soranz, Edson Alves de Araújo, Erno Harzheim, Maria de Fátima Marinho de Souza, James Macinko, Jonas Augusto Cardoso da Silveira, Márcia Cristina Oliveira da Rocha, Mário Roberto Dal Poz, Michael Duncan, Miguel Lago, Renato Tasca, Rudi Rocha, Cristina Vieira, Machado Alexandre, Marina Moreira, Costa Pittella, Rafaela Silva Moreira,
Primary health care in Brazil has a well-organised approach which is the result of sustained commitment to providing high quality primary health care for the whole population.The Family Health Strategy, launched in 1994, has been a key pillar of the efforts to reorganise and strengthen primary health care in Brazil.Since its implementation, a growing share of the Brazilian population can benefit from free access to a community-based approach to preventive and primary health care services.An extensive ...
Tópico(s): Global Health Care Issues
2009 - Organization for Economic Cooperation and Development | OECD Reviews of Health Systems
Produção Nacional
Revisado por pares
Cláudia Maria de Castro Gomes, Daniel Giannella‐Neto, Mônica Elinor Alves Gama, Júlio César Rodrigues Pereira, Marliane Batista Campos, Carlos Eduardo Pereira Corbett,
The role of the insulin-like growth factor I (IGF-I) system and nutritional status was studied in 241 children from a Brazilian area endemic for visceral leishmaniasis (VL). Thirty-nine children had the active form, 20 were oligosymptomatic, 38 were asymptomatic and 144 were not infected. Serum concentrations of growth hormone (GH), total and free IGF-I and IGF binding-protein 3 (IGFBP3) were measured by radioimmunoassay. Nutritional status was evaluated by anthropometric indicators and biochemical ...
Tópico(s): Research on Leishmaniasis Studies
2007 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Mônica Elinor Alves Gama, Jackson M. L. Costa, Júlio César Rodrigues Pereira, Cláudia Maria de Castro Gomes, Carlos Eduardo Pereira Corbett,
The factors determining the development or not of visceral leishmaniasis (VL) have not been completely identified, but a Leishmania-specific cellular immune response seems to play a fundamental role in the final control of infection. Few studies are available regarding the production of cytokines in the subclinical form of VL, with only the production of IFN-g and TNF-a known. The aim of the present study was to identify immunological markers for the oligosymptomatic or subclinical form of VL. A ...
Tópico(s): Parasites and Host Interactions
2004 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Alexandra Machado, Isabel Pereira, Filomena Costa, Ana Maria Martins Brandão, José Eduardo Pereira, Ana Colette Maurício, José D. Santos, María Inês Amaro, Rui I. Falacho, R. Coelho, N. Cruz, Miguel Gama,
Abstract Objectives This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone. Methods Twelve participants requiring pre-molar tooth extraction and implant placement were enrolled in this study. BL® granules (250–500 µm) were administered to 6 randomized participants whereas the ...
Tópico(s): Periodontal Regeneration and Treatments
2023 - Springer Nature | Clinical Oral Investigations
Produção Nacional
Revisado por pares
Marcelo El Khouri, Quirino Cordeiro, Diogo Arantes Behling Pereira da Luz, Leandro Savoy Duarte, Mônica Elinor Alves Gama, Carlos Eduardo Pereira Corbett,
CONTEXT: Hepatitis B and hepatitis C infection has been an important cause of morbidity and mortality around the world. However there are few investigations regarding the prevalence and possible risk factors for these diseases in Brazil, particularly in Amazon region, where there are some endemic focus. OBJECTIVES: To determine the prevalence of hepatitis B and hepatitis C in the city of Buriticupu, MA, located in the Brazilian Eastern Amazon region, and try to explore the risk factors for these ...
Tópico(s): Hepatitis Viruses Studies and Epidemiology
2010 - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) | Arquivos de Gastroenterologia
Produção Nacional
Revisado por pares
Carolina Pereira, Márcio H. Miname, Márcia Makdisse, Carolina Yukari Veludo Watanabe, Antônio Eduardo Pereira Pesaro, Cinthia E. Jannes, Roberto Kalil Filho, Alexandre C. Pereira, Raúl D. Santos,
Background Familial hypercholesterolemia is characterized by elevated plasma cholesterol and early coronary arterial disease onset. However, few studies investigated the association of heterozygous familial hypercholesterolemia with peripheral arterial disease. Methods In a cross sectional study 202 heterozygous familial hypercholesterolemia patients (91% confirmed by molecular diagnosis) were compared to 524 normolipidemic controls. Peripheral arterial disease was diagnosed by ankle-brachial index ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2015 - Elsevier BV | Atherosclerosis
Produção Nacional
Revisado por pares
Lia Laura Lewis‐Ximenez, Georg M. Lauer, Julian Schulze zur Wiesch, Paulo Sérgio Fonseca de Sousa, Cleber F. Ginuino, Gláucia Paranhos‐Baccalà, Hanno Ulmer, Karl Pfeiffer, Hans H. Goebel, João Luiz Pereira, Jaqueline Mendes Oliveira, Clara Fumiko Tachibana Yoshida, Elisabeth Lampe, Carlos Eduardo Pereira Velloso, Marcelo Alves Pinto, Henrique Sergio Coelho, Adílson José de Almeida, Carlos Augusto Fernandes, Arthur Y. Kim, Alexander Strasak,
The natural outcome of infection with hepatitis C virus (HCV) varies substantially among individuals. However, little is known about host and viral factors associated with a self-limiting or chronic evolution of HCV infection.From 1 January 2001 through 31 December 2008, a consecutive series of 65 patients from Rio de Janeiro, Brazil, with a well-documented diagnosis of acute HCV infection, acquired via various routes, were enrolled in this study. Patients were prospectively followed up for a median ...
Tópico(s): Liver Disease Diagnosis and Treatment
2010 - Oxford University Press | Clinical Infectious Diseases
Produção Nacional
Revisado por pares
Amaro César Lima de Assis, Larissa Pereira Alves, João Paulo Tavares Malheiro, Alana Rafaela Albuquerque Barros, Edvânia Emannuelle Pinheiro-Santos, Eduardo Pereira de Azevedo, Harley da Silva Alves, João Augusto Oshiro, Bolívar Ponciano Goulart de Lima Damasceno,
Cellulose is among the top 5 excipients used in the pharmaceutical industry. It has been considered one of the main diluents used in conventional and modern dosage forms. Therefore, different raw materials of plant origin have been evaluated as potential alternative sources of cellulose. In this context, Opuntia ficus-indica L. Miller (palma forrageira), a plant of the cactus family that has physiological mechanisms that provide greater productivity with reduced water requirements, is an interesting ...
Tópico(s): Growth and nutrition in plants
2019 - Multidisciplinary Digital Publishing Institute | Polymers
Produção Nacional
Natália Pereira dos Santos, Rodrigo Martins Mitsunaga, Daniel Lago Borges, Marina de Albuquerque Gonçalves Costa, Thiago Eduardo Pereira Baldez, Ilka Mendes Lima, Karol Cristina Fonseca Moura, Josimary Lima da Silva Lula,
Hypoxemia is a frequent pulmonary complication in the postoperative coronary artery bypass graft. Detection of factors associated with their occurrence may indicate patients at risk for this complication, which allows tracing specific therapeutic and consequently reduce morbidity and mortality.To identify related factors to hypoxemia occurrence in immediate coronary artery bypass graft postoperative.In this retrospective cohort study, we studied 100 patients submitted to elective om-pump artery ...
Tópico(s): Mechanical Circulatory Support Devices
2013 - Brazilian Society of Cardiovascular Surgery | Brazilian Journal of Cardiovascular Surgery
Produção Nacional
Revisado por pares
Áislan Carvalho Vivarini, Renata M. Pereira, Karina Luiza Dias Teixeira, Teresa Calegari-Silva, Maria Bellio, Márcia Dalastra Laurenti, Carlos Eduardo Pereira Corbett, Cláudia Maria de Castro Gomes, Rodrigo Pedro Soares, Aristóbolo M. Silva, Fernando Tobias Sílveira, Ulisses Gazos Lopes,
We investigated the type I interferon (IFN-1)/PKR axis in the outcome of the Leishmania (Leishmania) amazonensis infection, along with the underlying mechanisms that trigger and sustain this signaling pathway. Reporter assays of cell extracts from RAW-264.7 macrophages infected with L. (L.) amazonensis or HEK-293T cells cotransfected with TLR2 and PKR promoter constructions were employed. Primary macrophages of TLR2-knockout (KO) or IFNR-KO mice were infected, and the levels of PKR, IFN-1, and superoxide ...
Tópico(s): Leptospirosis research and findings
2011 - Wiley | The FASEB Journal
Produção Nacional
Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, A Garrido, Murillo Santucci César de Assunção, Carmen Sílvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva, Fabrício Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, Leonardo José Rolim Ferraz,
In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Instituto Israelita de Ensino e Pesquisa Albert Einstein | Einstein (São Paulo)
Produção Nacional
Revisado por pares
Diogo Arantes Behling Pereira da Luz, Ulysses Ribeiro, Celso Alberto Chassot, F De Salles Collet e Silva, Ivan Cecconello, Carlos Eduardo Pereira Corbett,
HistopathologyVolume 53, Issue 6 p. 740-742 Carnoy's solution enhances lymph node detection: an anatomical dissection study in cadavers D A B P Luz, D A B P Luz Departments of Pathology and Gastroenterology, University of São Paulo School of Medicine, São Paulo, SP, BrazilSearch for more papers by this authorU Ribeiro Jr, U Ribeiro Jr Departments of Pathology and Gastroenterology, University of São Paulo School of Medicine, São Paulo, SP, BrazilSearch for more papers by this authorC Chassot, C Chassot ...
Tópico(s): Colorectal Cancer Surgical Treatments
2008 - Wiley | Histopathology
Produção Nacional
Revisado por pares
Bárbara Pereira da Silva, Renata Celi Lopes Toledo, Marcella Duarte Villas Mishima, Maria Eliza de Castro Moreira, Christiane Mileib Vasconcelos, Carlos Eduardo Pereira, Lukiya Silva Campos Favarato, Neuza Maria Brunoro Costa, Hércia Stampini Duarte Martino,
The study investigated the influence of chia consumption on inflammation, oxidative stress, and lipid profiles in female ovariectomized rats fed a high-fat diet.
Tópico(s): Phytochemical and Pharmacological Studies
2019 - Royal Society of Chemistry | Food & Function
Produção Nacional
Revisado por pares
Fernando Tobias Sílveira, R. Lainson, Elza Alves Pereira, Adelson Alcimar Almeida de Souza, Marliane Batista Campos, Eugênia J. Chagas, Cláudia Maria de Castro Gomes, Márcia Dalastra Laurenti, Carlos Eduardo Pereira Corbett,
Tópico(s): Trypanosoma species research and implications
2008 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Marcello Casaccia Bertoluci, Augusto Pimazoni-Netto, Antônio Carlos Pires, Antônio Eduardo Pereira Pesaro, Beatriz D. Schaan, Bruno Caramelli, Carísi Anne Polanczyk, Carlos Serrano, Danielle Menosi Gualandro, Domingos Augusto Cherino Malerbi, Emílio Hideyuki Moriguchi, Flávio Borelli, João Eduardo Nunes Salles, José Mariani Júnior, Luís Eduardo Paim Rohde, Luís Henrique Santos Canani, Luı́z Antonio Machado César, Marcos Antônio Tambascia, Maria Teresa Zanella, Miguel Gus, Rafael Selbach Scheffel, Raul Dias Santos,
There is a very well known correlation between diabetes and cardiovascular disease but many health care professionals are just concerned with glycemic control, ignoring the paramount importance of controlling other risk factors involved in the pathogenesis of serious cardiovascular diseases. This Position Statement from the Brazilian Diabetes Society was developed to promote increased awareness in relation to six crucial topics dealing with diabetes and cardiovascular disease: Glicemic Control, ...
Tópico(s): Diabetes Treatment and Management
2014 - BioMed Central | Diabetology & Metabolic Syndrome
Produção Nacional
Revisado por pares
Teresa Calegari-Silva, Áislan de Carvalho Vivarini, Renata M. Pereira, Karina Luiza Dias Teixeira, Carolina Torturella Rath, Amanda S. S. Pacheco, Gabrielle B. L. Silva, Charlene A. S. Pinto, José Vitorino dos Santos, Alessandra Mattos Saliba, Carlos Eduardo Pereira Corbett, Cláudia Maria de Castro Gomes, Nicolás Fasel, Ulisses Gazos Lopes,
The induced expression of nitric oxide synthase (iNOS) controls the intracellular growth of Leishmania in infected macrophages. Histones deacetylases (HDACs) negatively regulate gene expression through the formation of complexes containing transcription factors such as NF-κB p50/50. Herein, we demonstrated the occupancy of p50/p50_HDAC1 to iNOS promoter associated with reduced levels of H3K9Ac. Remarkably, we found increased levels of HDAC1 in L. amazonensis-infected macrophages. HDAC1 upregulation ...
Tópico(s): Signaling Pathways in Disease
2018 - Wiley | European Journal of Immunology
Produção Nacional
Revisado por pares
Renato Kawahisa Levin, Marcelo Katz, Paulo Hilário Nascimento Saldiva, Adriano Caixeta, Marcelo Franken, Carolina Pereira, Salo Coslovsky, Antônio Eduardo Pereira Pesaro,
Background In high-income temperate countries, the number of hospitalizations for heart failure (HF) and acute myocardial infarction (AMI) increases during the winter. This finding has not been fully investigated in low- and middle-income countries with tropical and subtropical climates. We investigated the seasonality of hospitalizations for HF and AMI in Sao Paulo (Brazil), the largest city in Latin America. Methods This was a retrospective study using data for 76,474 hospitalizations for HF and ...
Tópico(s): Health disparities and outcomes
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Marjorie Caroline Liberato Cavalcanti Freire, G.D. Noske, Natália Vitória Bitencourt, Paulo R. S. Sanches, Norival A. Santos‐Filho, Victor O. Gawriljuk, Eduardo Pereira de Souza, Victor H. R. Nogueira, Mariana Ortiz de Godoy, A.M. Nakamura, R.S. Fernandes, André S. Godoy, María A. Juliano, Bianca de Miranda Peres, Cecília Gomes Barbosa, Carolina Borsoi Moraes, Lúcio H. Freitas-Júnior, Eduardo Maffud Cilli, Rafael V. C. Guido, Glaucius Oliva,
The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and public health systems throughout the world. In recent years, peptide-based therapeutics have been widely studied and developed to treat infectious diseases, including viral infections. Herein, the antiviral effects of the lysine linked dimer des-Cys11, Lys12,Lys13-(pBthTX-I)2K ((pBthTX-I)2K)) and derivatives against SARS-CoV-2 are reported. The lead peptide (pBthTX-I)2K and derivatives showed attractive inhibitory ...
Tópico(s): vaccines and immunoinformatics approaches
2021 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Joquebede Rodrigues Pereira, Gabriela Suassuna Bezerra, Allanny Alves Furtado, Thaís Gomes de Carvalho, Valéria Costa da Silva, Amanda Lins Bispo Monteiro, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Antônio Euzébio Goulart Santana, Matheus de Freitas Fernandes‐Pedrosa, Daniel De Melo Silva, Eduardo Pereira de Azevedo, Tânia Maria Sarmento Silva, Telma Maria Araújo Moura Lemos, Ádley Antonini Neves de Lima,
Chitosan films entrapped with the Mansoa hirsuta fraction (CMHF) was developed as a new dressing for wound care. The chromatographic profile of the M. hirsuta fraction (MHF) was evaluated by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry, and the results showed that MHF is rich in acid triterpenes. Physicochemical characterization of the films prepared using the solvent casting method was performed by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction ( ...
Tópico(s): Bee Products Chemical Analysis
2020 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Revisado por pares
Márcia Dalastra Laurenti, Anders Örn, I.L. Sinhorini, Carlos Eduardo Pereira Corbett,
Complement-depleted and -non-depleted BALB/c mice were inoculated with Leishmania (Leishmania) amazonensis promastigotes into the hind footpad to study the role of the complement system in cutaneous leishmaniasis. Total serum complement activity was measured by hemolytic assay and C3 fragment deposit at the inoculation site was determined by direct immunofluorescence in the early period of infection, i.e., at 3, 24, 48 h and 7 days post-infection. The inflammatory reaction and the parasite burden ...
Tópico(s): Complement system in diseases
2004 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research