Produção Nacional
Revisado por pares
Thais Cardoso Bitencourt, José Eduardo Vargas, Andrew Oliveira Silva, Lucas Rosa Fraga, Eduardo Cremonese Filippi–Chiela,
Abstract Cellular senescence is a state of permanent growth arrest. It can be triggered by telomere shortening (replicative senescence) or prematurely induced by stresses such as DNA damage, oncogene overactivation, loss of tumor suppressor genes, oxidative stress, tissue factors, and others. Advances in techniques and experimental designs have provided new evidence about the biology of senescent cells (SnCs) and their importance in human health and disease. This review aims to describe the main aspects ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2024 - Wiley | Aging Cell
Produção Nacional
Alexander Vargas, Eduardo Saad, George Santiago Dimech, Roselene Hans Santos, Maria Auxiliadora Vieira Caldas Sivini, Luciana Carolina Albuquerque, Patrícia Michelly Santos Lima, Idalacy de Carvalho Barreto, Michelly Evangelista de Andrade, Nathalie Mendes Estima, Patrícia Ismael de Carvalho, Rayane Souza de Andrade Azevedo, Rita de Cássia de Oliveira Vasconcelos, Romildo Siqueira de Assunção, Lívia Carla Vinhal Frutuoso, Greice Madeleine Ikeda do Carmo, Priscila Bochi de Souza, Marcelo Yoshito Wada, Wanderson Kleber de Oliveira, Cláudio Maierovitch Pessanha Henriques, Jadher Pércio, Alexander Vargas, Eduardo Saad, George Santiago Dimech, Roselene Hans Santos, Maria Auxiliadora Vieira Caldas Sivini, Luciana Carolina Albuquerque, Patrícia Michelly Santos Lima, Idalacy de Carvalho Barreto, Michelly Evangelista de Andrade, Nathalie Mendes Estima, Patrícia Ismael de Carvalho, Rayane Souza de Andrade Azevedo, Rita de Cássia de Oliveira Vasconcelos, Romildo Siqueira de Assunção, Lívia Carla Vinhal Frutuoso, Greice Madeleine Ikeda do Carmo, Priscila Bochi de Souza, Marcelo Yoshito Wada, Wanderson Kleber de Oliveira, Cláudio Maierovitch Pessanha Henriques, Jadher Pércio,
to describe the first cases of microcephaly possibly related to Zika virus in live born babies reported in the Metropolitan Region of Recife, Pernambuco State, Brazil.this was a descriptive case series study (cases reported between August 1st and October 31st 2015), using medical record data and data from a questionnaire answered by the mothers of the babies.40 microcephaly cases were confirmed, distributed in eight municipalities within the Metropolitan Region, with Recife itself having the highest ...
Tópico(s): Syphilis Diagnosis and Treatment
2016 - MINISTÉRIO DA SAÚDE | Epidemiologia e Serviços de Saúde
Produção Nacional
Revisado por pares
José Eduardo Vargas, Eduardo Cremonese Filippi–Chiela, Taís Suhre, Franciele Kipper, Diego Bonatto, Guido Lenz,
Cellular senescence is an irreversible block of cellular division, and induction of senescence is being considered for treatment of many cancer types, mainly those resistant to classical pro-apoptotic therapies. Resveratrol (Rsv) and quercetin (Quer), two natural polyphenols, are able to induce senescence in different cancer models, including gliomas, the most common and aggressive primary brain tumor. These polyphenols modulate the activity of several proteins involved in cell growth and death in ...
Tópico(s): Autophagy in Disease and Therapy
2014 - NRC Research Press | Biochemistry and Cell Biology
... Fábio Everton Maciel, Carlos Eduardo Rosa, Marcelo Alves Vargas, Luiz Eduardo Maia Nery Circadian rhythm of pigment migration induced ...
Tópico(s): Neurobiology and Insect Physiology Research
1968 - University of Chicago Press | Physiological Zoology
C. A. Vargas, Eduardo Basurto, Lev Guzmán-Vargas, F. Angulo‐Brown,
We use a simple spring-block system as a qualitative analogous of a seismic fault. The role of the asperities present in a real seismic fault is played by sandpapers of several grades. With this experimental array Gutenberg–Richter type-laws are obtained. We also observed that the maximum characteristic event in each experimental run depends on both the mass of the sliding blocks and the age of the sandpapers used at the interface between the blocks and the rough track.
Tópico(s): NMR spectroscopy and applications
2008 - Elsevier BV | Physica A Statistical Mechanics and its Applications
Produção Nacional
Revisado por pares
Daiane Paula Baldissarelli, Gean Delise Leal Pasquali Vargas, Eduardo Pavan Korf, Leandro Galon, Cíntia Regina Kaufmann, José Barbosa dos Santos,
ABSTRACT: After years of pesticide application, often indiscriminately, damage has been caused to the environment, as well as to agronomic crops grown in contaminated areas. In water treatment, techniques based on physical and/or physicochemical processes are used, being formed secondary oxidizing agents responsible for the mineralization of contaminants present in the herbicides, thus causing the degradation process. However, few studies have demonstrated the effectiveness of these techniques in ...
Tópico(s): Microbial Fuel Cells and Bioremediation
2019 - Sociedade Brasileira da Ciência das Plantas Daninhas | Planta Daninha
Produção Nacional
Revisado por pares
André Luís Marin Vargas, Eduardo Blando, Roberto Hübler,
Instrumented Hardness Tests (IHT), also known as nanoindentation, establishes itself throughout the years as a standard method to characterize superficial elasto – plastic properties of materials, with a greater capability to evaluate thin films. The main advantage of this test lies on the application of dynamical load – unload cycles, generally with values of few mN and displacements below 200 nm, granting more information about the material beyond hardness, as elastic modulus, creep, fracture resistance, ...
Tópico(s): Force Microscopy Techniques and Applications
2019 - Elsevier BV | Measurement
Produção Nacional
Revisado por pares
Bárbara Martins-Andrade, Sara Ferreira dos Santos Costa, Maria Sissa Pereira Sant’Ana, Albina Altemani, Pablo Agustín Vargas, Eduardo Rodrigues Fregnani, Lucas Guimarães Abreu, Aline Carvalho Batista, Felipe Paiva Fonseca,
The presence of lymphovascular invasion is considered a prognostic determinant for different human neoplasms and is frequently taken into account by surgeons and oncologists to determine patients' treatment. However, the exact frequency of this microscopic event and its prognostic impact for patients affected by adenoid cystic carcinoma (AdCC) remains unclear. Therefore, the aim of this study was to carry out a systematic review and meta-analysis to address the prevalence and the prognostic potential ...
Tópico(s): Vascular Malformations and Hemangiomas
2019 - Elsevier BV | Oral Oncology
Alejandro I. Maass, Francisco J. Vargas, Eduardo I. Silva,
In this paper we focus on networked control systems subject to data dropouts. We consider that the controller communicates with the plant through multiple independent erasure channels, and that each actuator sends acknowledgement packages to the controller. We restrict our attention to the optimal design of a class of controllers that embeds a data dropout compensator and where, besides this compensation mechanism, all processing is an affine function of the available data. Our first result shows ...
Tópico(s): Control Systems and Identification
2016 - Elsevier BV | Automatica
Produção Nacional
Revisado por pares
Rodrigo Ramírez‐Campillo, Francisco Gallardo-Fuentes, Carlos Henríquez‐Olguín, César Meylan, Cristian Martínez‐Salazar, Cristián Álvarez, Alexis Caniuqueo Vargas, Eduardo Lusa Cadore, Míkel Izquierdo,
Ramírez-Campillo, R, Gallardo, F, Henriquez-Olguín, C, Meylan, CMP, Martínez, C, Álvarez, C, Caniuqueo, A, Cadore, EL, and Izquierdo, M. Effect of vertical, horizontal, and combined plyometric training on explosive, balance, and endurance performance of young soccer players. J Strength Cond Res 29(7): 1784–1795, 2015—The aim of this study was to compare the effects of 6 weeks of vertical, horizontal, or combined vertical and horizontal plyometric training on muscle explosive, endurance, and balance ...
Tópico(s): Sports Dynamics and Biomechanics
2015 - Lippincott Williams & Wilkins | The Journal of Strength and Conditioning Research
Edwin Pino-Vargas, Eduardo Chávarri-Velarde, Eusebio Ingol-Blanco, Fabricio Mejía, Ana Cruz, Alissa Vera,
Global projections of climate change indicate negative impacts on hydrological systems, with significant changes in precipitation and temperature in many parts of the world. As a result, floods and droughts are expected. This article discusses the potential effects of climate change and variability on the maximum precipitation, temperature, and hydrological regime in Devil’s Creek, Tacna, Peru. The outputs of precipitation and daily temperature of fifteen regional climate models were used for the ...
Tópico(s): Cryospheric studies and observations
2022 - Multidisciplinary Digital Publishing Institute | Hydrology
Nohra E. Beltran-Vargas, Eduardo Peña-Mercado, Concepción Sánchez‐Gómez, Mario García‐Lorenzana, Juan‐Carlos Ruiz, Izlia J. Arroyo‐Maya, Sara Huerta‐Yépez, José Campos‐Terán,
Natural biopolymer scaffolds and conductive nanomaterials have been widely used in cardiac tissue engineering; however, there are still challenges in the scaffold fabrication, which include enhancing nutrient delivery, biocompatibility and properties that favor the growth, maturation and functionality of the generated tissue for therapeutic application. In the present work, different scaffolds prepared with sodium alginate and chitosan (alginate/chitosan) were fabricated with and without the addition ...
Tópico(s): 3D Printing in Biomedical Research
2022 - Multidisciplinary Digital Publishing Institute | Polymers
Produção Nacional
Revisado por pares
Carlos H. Barrios, Gustavo Werutsky, Alejandro Mohar, Ana S. Ferrigno, Bettina Müller, Brittany L. Bychkovsky, Carlos José Castro E, Claudia Uribe, Cynthia Villarreal‐Garza, Enrique Soto‐Pérez‐de‐Celis, Francisco Gutiérrez-Delgado, Ji Seok Kim, Julia Ismael, Lucı́a Delgado, Luiz Antônio Santini, Nelson Teich, Pamela Contreras Chavez, Pedro Emanuel Rubini Liedke, Pedro Exman, Romualdo Barroso‐Sousa, Stephen Stefani, Suyapa A Bejarano Cáceres, Taiane Francieli Rebelatto, Tania Pastrana, Yanin Chávarri-Guerra, Y Sanguineti Vargas, Eduardo Cazap,
The increasing burden of cancer represents a substantial problem for Latin America and the Caribbean. Two Lancet Oncology Commissions in 2013 and 2015 highlighted potential interventions that could advance cancer care in the region by overcoming existing challenges. Areas requiring improvement included insufficient investment in cancer control, non-universal health coverage, fragmented health systems, inequitable concentration of cancer services, inadequate registries, delays in diagnosis or treatment ...
Tópico(s): Economic and Financial Impacts of Cancer
2021 - Elsevier BV | The Lancet Oncology
Ana K. Herrera-Vargas, Eduardo García-Rodríguez, Monserrat Olea‐Flores, Miguel A. Mendoza‐Catalán, Eugenia Flores‐Alfaro, Napoleón Navarro‐Tito,
The acquired ability to induce the formation of a functional vasculature is a hallmark of cancer. Blood vessels in tumors are formed through various mechanisms, among the most important in cancer biology, angiogenesis, and vasculogenic mimicry have been described. Leptin is one of the main adipokines secreted by adipocytes in normal breast tissue and the tumor microenvironment. Here, we provide information on the relationship between leptin and the development of angiogenesis and vasculogenic mimicry ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2021 - Elsevier BV | Cytokine & Growth Factor Reviews
Moisés Martínez‐Castillo, D. Rosique-Oramas, Zaira Medina‐Ávila, José Luis Pérez-Hernández, Fátima Higuera-de la Tijera, Daniel Santana‐Vargas, Eduardo E. Montalvo‐Javé, J.F. Sánchez-Ávila, Aldo Torre, David Kershenobich, Gabriela Gutiérrez‐Reyes,
Tópico(s): Liver Diseases and Immunity
2020 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Produção Nacional
Revisado por pares
Luiz Alberto Modesti, Alexandre Silva de Vargas, Eduardo Luís Schneider,
Epoxy-based adhesives have been widely used for the recovery of concrete structures. This study is aimed at studying the performance of six epoxy adhesives on the bond strength between two conventional concretes of different strengths when subjected to the slant shear test. First, the physical and mechanical characteristics of the six adhesives and the concrete used were studied. The factors investigated were the viscosity and the compressive strength of the adhesives during their working life, ...
Tópico(s): Innovative concrete reinforcement materials
2020 - Elsevier BV | International Journal of Adhesion and Adhesives
Brenda Vargas, Eduardo Coutiño‐González, Oscar Ovalle-Encinia, C. Sánchez-Aké, Diego Solis‐Ibarra,
Layered double perovskites have the potential to further expand the vast space of optoelectronic properties and applications of halide perovskites. Among the ∼60 known members, to date only the ⟨111⟩-oriented layered double perovskites, Cs4Cd1–xMnxBi2Cl12, have shown efficient photoluminescence (PL). The replacement of Bi with Sb in these materials was investigated, resulting in two new families of layered inorganic perovskite alloys with full solubility. The first, Cs4Cd1–xMnxSb2Cl12, exhibits a PL ...
Tópico(s): Luminescence Properties of Advanced Materials
2020 - American Chemical Society | The Journal of Physical Chemistry Letters
William Omar Contreras López, Paula Alejandra Navarro, Marcos David Vargas, Eduardo Alape, Paul Anthony Camacho,
To compare pulsed radiofrequency (PRF) treatment with continuous radiofrequency (CRF) to improve pain, functionality, and safety profile in patients with facet joint chronic low back pain. A systematic, critical review of recent literature was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Embase, Cochrane, Clinical Trials, and LILACS databases were searched. Medical Subject Heading terms were "low back pain," "zygapophyseal joint," ...
Tópico(s): Spine and Intervertebral Disc Pathology
2018 - Elsevier BV | World Neurosurgery
Gerardo A. González-Martínez, Tamara Jurado‐Vázquez, Diego Solis‐Ibarra, Brenda Vargas, Elı́ Sánchez-González, Ana Martı́nez, Rubicelia Vargas, Eduardo González‐Zamora, Ilich A. Ibarra,
EtOH adsorption–desorption properties of MIL-53(Al)-TDC along with the confinement of small amounts of water to enhance its CO 2 capture, and the reversible capture of iodine are presented in this article.
Tópico(s): Zeolite Catalysis and Synthesis
2018 - Royal Society of Chemistry | Dalton Transactions
Catalina Rey-Valeirón, Keila Pérez, Lucía Guzmán, Javier López-Vargas, Eduardo Valarezo,
The current concern about resistance to acaricides and the impact of toxic waste on the environment has led to the search of vegetal alternatives in the control of the brown tick of the dog Rhipicephalus sanguineus. Schinus molle L. (Anacardiaceae) derivatives have been associated with insecticidal, antimicrobial and antiprotozoal activities and essential oil showed to be lethal to R. microplus larvae. This study aimed at evaluating the acaricidal effect of essential oil of S. molle (EOSm) on engorged ...
Tópico(s): Vector-borne infectious diseases
2018 - Springer Science+Business Media | Experimental and Applied Acarology
Fernando Gamino-Sánchez, Isabel V. Hernández-Gutiérrez, Alberto Rosales, Francisco J. Gallegos‐Funes, Dante Mújica‐Vargas, Eduardo Ramos‐Díaz, Blanca E. Carvajal-Gámez, Jean Marie Vianney Kinani,
In this paper, we present the Block-Matching Fuzzy C-Means (BMFCM) clustering algorithm to segment RGB color images degraded with Additive White Gaussian Noise (AWGN). The contribution of this paper is threefold, namely, noise level estimation, denoising and segmentation. First, two Additive White Gaussian Noise estimation algorithms are proposed to compute the noise variance of the observed noisy color image. Second, we propose an image denoising method based on the enhanced sparse representation ...
Tópico(s): Advanced Image Fusion Techniques
2018 - Elsevier BV | Engineering Applications of Artificial Intelligence
Produção Nacional
Revisado por pares
Manuel A. Falcão, Rodrigo Scopel, Rafael N. Almeida, Alexandre Timm do Espirito Santo, Gustavo do Nascimento Franceschini, José Jacques Garcez, Rubem Mário Figueiró Vargas, Eduardo Cassel,
Catharanthus roseus is a rich source of alkaloids, being two dimeric alkaloids extensively used as antineoplastic drugs, vinblastine and vincristine. In this work was performed an optimization of the supercritical fluid extraction of vinblastine from C. roseus using ethanol as co-solvent for CO2 at different temperatures (40, 50, or 60 °C) and pressure equal to 300 bar. It was also evaluated the co-solvent ratio influence (2, 5 and 10% w/w). After HPLC/UV analysis the viability of this method of extraction ...
Tópico(s): Heat and Mass Transfer in Porous Media
2017 - Elsevier BV | The Journal of Supercritical Fluids
Anina Stäubli, Samuel U. Nussbaumer, Simon Allen, Christian Huggel, María Arguello, Felipe A. P. L. Costa, Christian Hergarten, Rodney Martínez, Jaime Alberto Restrepo Soto, Ruben R. Vargas, Eduardo Zambrano, Markus Zimmermann,
Mountains are fragile ecosystems with global importance, providing key ecosystems services within mountainous areas but also for the lowlands. However, mountain regions are prone to natural disasters and exposed to multiple hazards. In this chapter, we present four disaster databases (EM-DAT, NatCatSERVICE, DesInventar, Dartmouth) that store information about spatiotemporal occurrence and impacts of natural disasters in mountain areas. Quality and completeness of the four databases are compared and ...
Tópico(s): Viral Infections and Vectors
2017 - Springer International Publishing | Sustainable development goals series
Produção Nacional
Revisado por pares
Klécia M. Santos, Raquel de Melo Barbosa, Fernanda Grace A. Vargas, Eduardo Pereira de Azevedo, Antônio Cláudio da Silva Lins, Celso A. Câmara, Cícero Flávio Soares Aragão, Túlio Flávio Accioly de Lima e Moura, Fernanda Nervo Raffin,
β-lapachone (βlap) has shown potential use in various medical applications. However, its poor solubility has limited its systemic administration and clinical applications. The aim of this work is to develop solid dispersions of βlap using poly (ethylene glycol) (PEG 6000) and polyvinylpyrrolidone (PVP K30) as hydrophilic polymers and evaluate the dissolution rate in aqueous medium. Solid dispersions were prepared by solvent evaporation method using different weight ratios of βlap and hydrophilic polymer ( ...
Tópico(s): Synthesis and properties of polymers
2017 - Taylor & Francis | Drug Development and Industrial Pharmacy
Catalina Rey-Valeirón, Lucía Guzmán, Luis Rodrigo Saa, Javier López-Vargas, Eduardo Valarezo,
The use of bio-derivatives as acaricides would be an effective and safe method of tick control. The acaricidal effect of essential oils obtained from Bursera graveolens (Burseraceae) and Schinus molle (Anacardiaceae), traditionally used by indigenous Ecuadorian medicine as insecticides, was tested on larvae of cattle tick Rhipicephalus (Boophilus) microplus. Essential oils were obtained from mature fruits by hydrodistillation and analyzed by gas chromatography. The acaricidal activity of essential ...
Tópico(s): Plant Parasitism and Resistance
2017 - Taylor & Francis | Journal of Essential Oil Research
Produção Nacional
Revisado por pares
Alessandro N. Vargas, Eduardo F. Costa, Leonardo Acho, J.B.R. do Val,
This paper presents results to assure the almost sure stability of switching stochastic nonlinear systems. The switching rule governing the parameters of the system is driven by independent and identically distributed random variables. In this scenario, we prove that the switching nonlinear system is almost surely stable when appropriate matrices have spectral radius less than one. The result is particularly useful for applications, as shown in the paper by the application for an automotive electronic ...
Tópico(s): Advanced Control Systems Optimization
2017 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Automatic Control
Peter Potapov, Jan Dempewolf, Y. Talero, Matthew C. Hansen, Stephen V. Stehman, Christian Vargas, Eduardo Rojas, David Chacón Castillo, Eddy Mendoza, Aguirre Calderón, Renzo Giudice, Natalia Málaga, Brian R. Zutta,
Transparent, consistent, and accurate national forest monitoring is required for successful implementation of reducing emissions from deforestation and forest degradation (REDD+) programs. Collecting baseline information on forest extent and rates of forest loss is a first step for national forest monitoring in support of REDD+. Peru, with the second largest extent of Amazon basin rainforest, has made significant progress in advancing its forest monitoring capabilities. We present a national-scale ...
Tópico(s): Remote Sensing in Agriculture
2014 - IOP Publishing | Environmental Research Letters
Patricia Rivera, Sergio Arrabal, Antonio Vargas, Eduardo Blanco, Antonia Serrano, Francisco J. Pavà n, Fernando Rodrı́guez de Fonseca, Juan Suárez,
The N-acylethanolamines (NAEs), oleoylethanolamide (OEA) and palmithylethanolamide (PEA) are known to be endogenous ligands of PPARα receptors, and their presence requires the activation of a specific phospholipase D (NAPE-PLD) associated with intracellular Ca(2+) fluxes. Thus, the identification of a specific population of NAPE-PLD/PPARα-containing neurons that express selective Ca(2+)-binding proteins (CaBPs) may provide a neuroanatomical basis to better understand the PPARα system in the brain. For ...
Tópico(s): Pancreatic function and diabetes
2014 - Frontiers Media | Frontiers in Neuroanatomy
M. Hernandez-Vargas, Eduardo Cabal‐Yépez, Arturo García-Pérez,
Tópico(s): Engineering Diagnostics and Reliability
2014 - Elsevier BV | Computers & Electrical Engineering
Josef S Smolen, J. Braun, Maxime Dougados, Paul Emery, Oliver FitzGerald, Philip Helliwell, Arthur Kavanaugh, Tore K Kvien, Robert Landewé, Thomas A. Luger, Philip J. Mease, Ignazio Olivieri, John D. Reveille, Christopher T. Ritchlin, Martín Rudwaleit, Monika Schoels, Joachim Sieper, M. De Wit, Xenofon Baraliakos, Neil Betteridge, R Burgos-Vargas, Eduardo Collantes‐Estévez, Atul Deodhar, Dirk Elewaut, Laure Gossec, Merryn Jongkees, Mara Maccarone, Kurt Redlich, Filip Van den Bosch, James Cheng‐Chung Wei, Kevin Winthrop, Désirée van der Heijde,
Background Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective To define the treatment target for SpA including ankylosing spondylitis and psoriatic arthritis (PsA) and develop recommendations for achieving the target, including a treat-to-target management strategy. Methods Based on results of a systematic literature review and expert opinion, ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2013 - BMJ | Annals of the Rheumatic Diseases