Seiji Takashio, Mami Morioka, Masanobu Ishii, Kei Morikawa, Kyoko Hirakawa, Shinsuke Hanatani, Fumi Oike, Hiroki Usuku, Masafumi Kidoh, Seitaro Oda, Eiichiro Yamamoto, Kenichi Matsushita, Mitsuharu Ueda, Kenichi Tsujita,
Tafamidis improves prognosis in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). However, real-world data on the therapeutic effect of tafamidis are lacking. This study aimed to evaluate the clinical course, outcomes, and effectivity monitoring of the therapeutic effect of tafamidis in patients with ATTR-CM.This is a single-centre, retrospective observational study. We evaluated the clinical characteristics and outcomes in 125 consecutive patients with wild-type ATTR-CM (ATTRwt-CM) treated ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2023 - Wiley | ESC Heart Failure
Kei Nakajima, Eiji Oda, Eiichiro Kanda,
Background. High serum sodium (sNa) concentrations may be associated with hypertension, which deteriorates kidney function. However, it is equivocal whether high sNa concentrations are associated with impaired kidney function independently of blood pressure (BP) or serum chloride (sCl). Therefore, we addressed this issue in an apparently healthy population. Methods. Clinical variables including estimated glomerular filtration rate (eGFR) were examined in 3603 men and women (aged 25–75 years) who underwent ...
Tópico(s): Blood Pressure and Hypertension Studies
2015 - Taylor & Francis | Blood Pressure
Eiichiro Fukano, Masahiro Oda, Takayuki Kitasaka, Yasuhito Suenaga, Tetsuji Takayama, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori, Shigeru Nawano, Kensaku Mori,
This paper proposes a method for making correspondence between the supine and the prone positions of the colon in CT volumes. In CT colonography, two CT volumes in the supine and the prone positions are often taken to observe the whole colonic wall by comparing them. However, the colonic wall is soft and changes its shape when a patient changes positions. Therefore, physicians need to take the positional relations into account when comparing the two CT volumes. Calculation of the positional relations ...
Tópico(s): Colorectal Cancer Screening and Detection
2010 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Mami Morioka, Seiji Takashio, Naoya Nakashima, Masato Nishi, Akira Fujiyama, Kyoko Hirakawa, Shinsuke Hanatani, Hiroki Usuku, Eiichiro Yamamoto, Masafumi Kidoh, Seitaro Oda, Kenichi Matsushita, Mitsuharu Ueda, Kenichi Tsujita,
Background Several imaging parameters and biomarkers provide diagnostic and prognostic information for wild-type transthyretin amyloid cardiomyopathy. However, the relevance of these parameters and their association with cardiac amyloid load requires further substantiation. We aimed to elucidate the association of imaging parameters obtained using
Tópico(s): Medical Imaging and Pathology Studies
2022 - Wiley | Journal of the American Heart Association
Yukiko Nakano, Satoshi Tashiro, Eiji Kinoshita, Emiko Kinoshita‐Kikuta, Sou Takenaka, Miwa Miyoshi, Hiroshi Ogi, Eiichiro Sakoda, Noboru Oda, Kazuyoshi Suenari, Yukiji Tonouchi, Tomokazu Okimoto, Yukoh Hirai, Fumiharu Miura, Kazuko Yamaoka, Tohru Koike, Kazuaki Chayama,
Recently, it has been reported that under 20% of Brugada syndrome cases are linked to SCN5A mutations. The purpose of this study was to clarify whether abnormalities other than exonic mutations, such as splicing disorders, decreased mRNA expression levels, or membrane transport abnormalities of SCN5A, play a role in the pathogenesis of Brugada syndrome. We analyzed all SCN5A exons and splice sites using genomic DNA from 23 Brugada syndrome patients. We also analyzed the mRNA obtained from RV cardiomyocytes ...
Tópico(s): RNA and protein synthesis mechanisms
2006 - Wiley | Annals of Human Genetics
Daisuke Sueta, Masafumi Kidoh, Seitaro Oda, Koichi Egashira, Eiichiro Yamamoto, Koichi Kaikita, Kenichi Matsushita, Yutaka Yamamoto, Toshinori Hirai, Kenichi Tsujita,
Cardiac magnetic resonance (CMR) imaging is the golden standard used for the diagnosis of cancer therapy-related cardiac dysfunction (CTRCD). The consistency of cardiac computed tomography (CCT) in CTRCD cases using CMR imaging is investigated in this study.Methods and Results:In 7 clinically confirmed CTRCD patients, focal late enhancement was confirmed on both CCT and CMR for 4 patients. Myocardial extracellular volume (ECV) values measured by CCT and CMR were elevated in all patients, suggesting ...
Tópico(s): Advanced MRI Techniques and Applications
2021 - Japanese Circulation Society | Circulation Journal
Produção Nacional
Abraão Hadner Oliveira Bezerra, Rubens da Silva Ferreira, Paulo Moreira Pinto, Eduardo Lima dos Santos Gomes,
... turismo. Especificamente analisamos a série One Piece de Eiichiro Oda, que começou como mangá e posteriormente foi adaptada ...
Tópico(s): Cultural, Media, and Literary Studies
2024 - | Revista Multidisciplinar do Nordeste Mineiro
Kézia da Silva Calixto, João Batista Pereira Silva, Fernanda Suelen Freitas Da Silva, Gilberto Freire de Santana,
... é One Piece (1999), mangá e anime de Eiichiro Oda, que narra a história de Monkey D. Luffy, ...
Tópico(s): Cultural, Media, and Literary Studies
2023 - Servicios Academicos Intercontinentales | OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA
... at the time, surpassed only by veteran mangaka Eiichiro Oda's long-running series, One Piece.3 That ...
Tópico(s): Japanese History and Culture
2021 - | Film & history
The shonen hero in One Piece, a popular fantasy battle manga for boys, is described as a complete altruist although he longs to be the King of Pirates, that is, the top of ‘others’ in the social mainstream. Monkey D. Luffy and his crew, called the ‘Straw Hat Pirates’, seem to be derived from traditional Japanese heroes in period films or from the manly virtue called otoko-date in the Edo period: the outsiders who carry out ‘poetic justice’ by assisting the weak and resisting the strong, even at risk ...
Tópico(s): Japanese History and Culture
2011 - International Research Society for Children's Literature | International Research in Children s Literature
Kyoko Hirakawa, Seiji Takashio, Kyohei Marume, Masahiro Yamamoto, Shinsuke Hanatani, Eiichiro Yamamoto, Kenji Sakamoto, Yasuhiro Izumiya, Koichi Kaikita, Seitaro Oda, Daisuke Utsunomiya, Shinya Shiraishi, Mitsuharu Ueda, Taro Yamashita, Yasuyuki Yamashita, Yukio Ando, Kenichi Tsujita,
Abstract Aims Mutant transthyretin (ATTRm) amyloidosis is a systemic disease caused by the deposition of amyloid fibrils derived from mutated transthyretin. Although cardiac involvement impacts the prognosis of patients with ATTRm amyloidosis, the incidence of cardiac events, such as bradyarrhythmia, ventricular tachycardia, and heart failure, has not been fully elucidated. The aim of this study was to evaluate the prognosis and predictors of clinical outcomes, including cardiac events, in patients ...
Tópico(s): Neuroendocrine Tumor Research Advances
2018 - Wiley | ESC Heart Failure
Masato Nishi, Seiji Takashio, Mami Morioka, Akira Fujiyama, Naoya Nakashima, Kyoko Hirakawa, Shinsuke Hanatani, Hiroki Usuku, Eiichiro Yamamoto, Masafumi Kidoh, Seitaro Oda, Ryosuke Gushima, Kenichi Matsushita, Satoshi Fukushima, Mitsuharu Ueda, Kenichi Tsujita,
The accurate sensitivity of amyloid deposition in extracardiac tissue (subcutaneous tissue and gastrointestinal tract) has not been evaluated in transthyretin amyloidosis cardiomyopathy (ATTR-CM) patients. This study aimed to evaluate the sensitivity of amyloid deposition in obtained endomyocardial and extracardiac biopsies.Methods and Results: This study retrospectively evaluated 175 consecutive ATTR-CM patients (wild-type [ATTRwt]: 134, hereditary [ATTRv]: 41) who had positive findings on 99 mTc-labeled ...
Tópico(s): Eosinophilic Disorders and Syndromes
2022 - Japanese Circulation Society | Circulation Journal
Kei Nakajima, Eiji Oda, Eiichiro Kanda,
Low urine pH, a plausible predictor for chronic kidney disease and metabolic disorders, is often observed in obese individuals. However, the association between low urine pH and low body weight is equivocal. We examined clinical parameters including urine pH and body mass index (BMI) in a cross-sectional study of 3629 apparently healthy Japanese adults aged 25-80 years who underwent a health-screening check-up. Urine pH was lower and the prevalence of proteinuria was significantly higher in subjects ...
Tópico(s): Dialysis and Renal Disease Management
2015 - Taylor & Francis | Scandinavian Journal of Clinical and Laboratory Investigation
Daisuke Sueta, Seitaro Oda, Eiichiro Yamamoto, Masato Nishi, Koichi Kaikita, Masafumi Kidoh, Daisuke Utsunomiya, Takeshi Nakaura, Yasuyuki Yamashita, Kenichi Tsujita,
patient was eventually diagnosed with TC.One month later, follow-up echocardiography showed that the apical wall had improved.To the best of our knowledge, this is the first report to describe the use of myocardial ECV imaging on cardiac CT in a patient with TC.We believe this technology can support prompt clinical decision-making for patients with TC.
Tópico(s): Pericarditis and Cardiac Tamponade
2018 - Japanese Circulation Society | Circulation Journal
... Kinoshita–Kikuta, Sou Takenaka, Miwa Miyoshi, Hiroshi Ogi, Eiichiro Sakoda, Noboru Oda, Kazuyoshi Suenari, Yukiji Tonouchi, Tomokazu Okimoto, Yukoh Hirai, ... Takenaka MD4, Miwa Miyoshi MD1, Hiroshi Ogi MD1, Eiichiro Sakoda MD5, Tomokazu Okimoto MD6, Yukoh Hirai MD6, Noboru Oda MD1, Kazuyoshi Suenari MD1, Yukiji Tonouchi1, Fumiharu Miura ...
Tópico(s): RNA and protein synthesis mechanisms
2007 - Wiley | Annals of Human Genetics
Sayuri Masuda, Yukako Oda, Hiroyuki Sasaki, Junichi Ikenouchi, Tomohito Higashi, Masaya Akashi, Eiichiro Nishi, Mikio Furuse,
Epithelial cell contacts consist of not only bicellular contacts but also tricellular contacts, where the corners of three cells meet. At tricellular contacts, tight junctions (TJs) generate specialized structures termed tricellular TJs (tTJs) to seal the intercellular space. Tricellulin is the only known molecular component of tTJs and is involved in the formation of tTJs, as well as in the normal epithelial barrier function. However, the detailed molecular mechanism of how tTJs are formed and maintained ...
Tópico(s): Cell Adhesion Molecules Research
2011 - The Company of Biologists | Journal of Cell Science
Hiroki Usuku, Seiji Takashio, Eiichiro Yamamoto, Yui Kinoshita, Masato Nishi, Fumi Oike, Kyohei Marume, Kyoko Hirakawa, Noriaki Tabata, Seitaro Oda, Yohei Misumi, Mitsuharu Ueda, Hiroaki Kawano, Koichi Kaikita, Kenichi Matsushita, Yukio Ando, Hirotaka Matsui, Kenichi Tsujita,
We previously reported that a high score (2 or 3 points) according to the Kumamoto criteria, a combination of high-sensitivity cardiac troponin T (hs-cTnT) ≥0.308 ng/mL, the length of QRS ≥ 120 ms in electrocardiogram, and left ventricular (LV) posterior wall thickness ≥ 13.6 mm, increases the pretest probability of 99m Tc-labeled pyrophosphate (99m Tc-PYP) scintigraphy in patients with suspected transthyretin amyloid cardiomyopathy (ATTR-CM). However, some patients with a low score (0 or 1 point) show positive ...
Tópico(s): Medical Imaging and Pathology Studies
2020 - Wiley | Echocardiography
Kyohei Marume, Seiji Takashio, Masato Nishi, Kyoko Hirakawa, Masahiro Yamamoto, Shinsuke Hanatani, Seitaro Oda, Daisuke Utsunomiya, Shinya Shiraishi, Mitsuharu Ueda, Taro Yamashita, Kenji Sakamoto, Eiichiro Yamamoto, Koichi Kaikita, Yasuhiro Izumiya, Yasuyuki Yamashita, Yukio Ando, Kenichi Tsujita,
A recent study revealed a high prevalence of transthyretin (TTR) cardiac amyloidosis (CA) in elderly patients.
Tópico(s): Medical Imaging and Pathology Studies
2019 - Japanese Circulation Society | Circulation Journal
Fumi Oike, Hiroki Usuku, Eiichiro Yamamoto, Kyohei Marume, Seiji Takashio, Masanobu Ishii, Noriaki Tabata, Koichiro Fujisue, Kenshi Yamanaga, Daisuke Sueta, Shinsuke Hanatani, Yuichiro Arima, Satoshi Araki, Seitaro Oda, Hiroaki Kawano, Hirofumi Soejima, Kenichi Matsushita, Mitsuharu Ueda, Toshihiro Fukui, Kenichi Tsujita,
Abstract Aims To clarify the usefulness of left atrial (LA) function and left ventricular (LV) function obtained by two‐dimensional (2D) speckle tracking echocardiography to diagnose concomitant transthyretin amyloid cardiomyopathy (ATTR‐CM) in patients with aortic stenosis (AS). Methods and results We analysed 72 consecutive patients with moderate to severe AS who underwent 99m Tc‐pyrophosphate (PYP) scintigraphy at Kumamoto University Hospital from January 2012 to September 2020. We divided these 72 ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2022 - Wiley | ESC Heart Failure
Fumi Oike, Hiroki Usuku, Eiichiro Yamamoto, Toshihiro Yamada, Koichi Egashira, Mami Morioka, Masato Nishi, Takashi Komorita, Kyoko Hirakawa, Noriaki Tabata, Kenshi Yamanaga, Koichiro Fujisue, Shinsuke Hanatani, Daisuke Sueta, Yuichiro Arima, Satoshi Araki, Seiji Takashio, Seitaro Oda, Yohei Misumi, Hiroaki Kawano, Kenichi Matsushita, Mitsuharu Ueda, Hirotaka Matsui, Kenichi Tsujita,
Abstract Aims This study was performed to investigate whether left atrial (LA) strain by echocardiography provides prognostic information in patients with wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM). Methods and results Among 129 patients who were diagnosed with ATTRwt‐CM at Kumamoto University Hospital from December 2002 to December 2019, 113 patients who had enough information for two‐dimensional speckle tracking echocardiography were enrolled in this study. During a median follow‐ ...
Tópico(s): Parathyroid Disorders and Treatments
2021 - Wiley | ESC Heart Failure
Takafumi Emoto, Masafumi Kidoh, Seitaro Oda, Takeshi Nakaura, Yasunori Nagayama, Akira Sasao, Yoshinori Funama, Satoshi Araki, Seiji Takashio, Kenji Sakamoto, Eiichiro Yamamoto, Koichi Kaikita, Kenichi Tsujita, Yasuyuki Yamashita,
Tópico(s): Radiation Dose and Imaging
2019 - Springer Science+Business Media | European Radiology
Yasunori Nagayama, Takafumi Emoto, Hidetaka Hayashi, Masafumi Kidoh, Seitaro Oda, Takeshi Nakaura, Daisuke Sakabe, Yoshinori Funama, Noriaki Tabata, Masanobu Ishii, Kenshi Yamanaga, Koichiro Fujisue, Seiji Takashio, Eiichiro Yamamoto, Kenichi Tsujita, Toshinori Hirai,
BACKGROUND. A super-resolution deep learning reconstruction (SR-DLR) algorithm may provide better image sharpness than earlier reconstruction algorithms and thereby improve coronary stent assessment on coronary CTA. OBJECTIVE. The purpose of our study was to compare SR-DLR and other reconstruction algorithms in terms of image quality measures related to coronary stent evaluation in patients undergoing coronary CTA. METHODS. This retrospective study included patients with at least one coronary artery ...
Tópico(s): Advanced X-ray and CT Imaging
2023 - American Roentgen Ray Society | American Journal of Roentgenology
Hiroko Itagaki, Tomoko Yamamoto, Atsuko Hiroi, Kunio Kawanishi, Eiichiro Noguchi, Tetsuya Ohchi, Takako Kamio, Shingo Kameoka, Hideaki Oda, Yoji Nagashima,
Synchronous bilateral breast cancer is rare, and oncocytic carcinoma is an even rarer breast cancer histological subtype. In general, oncocytic tumors are defined as neoplasms with eosinophilic granular cytoplasm and have been reported in various organs. Oncocytic carcinoma of the breast was first documented by Gădăleanu and Craciun in 1987, and 48 cases have since been reported. The present study reports a case of synchronous bilateral breast oncocytic carcinoma. The patient was a 78‑year‑old woman. ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2017 - Spandidos Publishing | Oncology Letters
Hidetaka Hayashi, Seitaro Oda, Takafumi Emoto, Masafumi Kidoh, Yasunori Nagayama, Takeshi Nakaura, Daisuke Sakabe, Shinichi Tokuyasu, Kyoko Hirakawa, Seiji Takashio, Eiichiro Yamamoto, Kenichi Tsujita, Toshinori Hirai,
Myocardial extracellular volume (ECV) measured by cardiac magnetic resonance imaging (MRI) has been suggested as a marker of disease severity in pulmonary hypertension (PH). However, consistency between ECVs quantified by computed tomography (CT) and MRI has not been sufficiently investigated in (PH). We investigated the utility of CT-ECV in PH, using MRI-ECV as a reference standard.We evaluated 20 patients with known or suspected PH who underwent dual-energy CT, cardiac MRI, and right heart catheterization. ...
Tópico(s): Cardiovascular Function and Risk Factors
2022 - Elsevier BV | European Journal of Radiology
Hiroki Usuku, Seiji Takashio, Eiichiro Yamamoto, Toshihiro Yamada, Koichi Egashira, Mami Morioka, Masato Nishi, Takashi Komorita, Fumi Oike, Noriaki Tabata, Masanobu Ishii, Kenshi Yamanaga, Koichiro Fujisue, Daisuke Sueta, Yuichiro Arima, Satoshi Araki, Seitaro Oda, Yohei Misumi, Hiroaki Kawano, Kenichi Matsushita, Mitsuharu Ueda, Hirotaka Matsui, Kenichi Tsujita,
BackgroundThis study was performed to investigate whether right ventricular global longitudinal strain (RV-GLS) provides prognostic information in patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM).Methods and resultsAmong 129 patients who were diagnosed with ATTRwt-CM at Kumamoto University Hospital from December 2002 to December 2019, 111 patients who had enough information for two-dimensional speckle tracking imaging were retrospectively analyzed. During a median follow-up ...
Tópico(s): Parathyroid Disorders and Treatments
2022 - Elsevier BV | Journal of Cardiology
Koichi Egashira, Daisuke Sueta, Mai Tomiguchi, Masafumi Kidoh, Seitaro Oda, Hiroki Usuku, Kaori Hidaka, Lisa Goto‐Yamaguchi, Aiko Sueta, Takashi Komorita, Masafumi Takae, Fumi Oike, Koichiro Fujisue, Eiichiro Yamamoto, Shinsuke Hanatani, Seiji Takashio, Yuichiro Arima, Satoshi Araki, Koichi Kaikita, Kenichi Matsushita, Yutaka Yamamoto, Toshinori Hirai, Kenichi Tsujita,
Cardiotoxicity in the late phase after anthracycline drugs administration remains to be defined. Of the 44 patients who received anthracycline treatment, 7 were found to have cancer therapeutics–related cardiac dysfunction (CTRCD). The global longitudinal strain determined by echocardiography and myocardial extracellular volume fraction (ECV) determined by cardiac computed tomography (CCT) of the CTRCD(+) group were significantly higher than those of the control group and CTRCD(-) group, whereas there ...
Tópico(s): Polymer Nanocomposite Synthesis and Irradiation
2021 - Elsevier BV | IJC Heart & Vasculature
Naoto Kuyama, Seiji Takashio, Tetsuya Oguni, Masahiro Yamamoto, Kyoko Hirakawa, Masanobu Ishii, Shinsuke Hanatani, Seitaro Oda, Yasushi Matsuzawa, Hiroki Usuku, Eiichiro Yamamoto, Toshinori Hirai, Mitsuharu Ueda, Kenichi Tsujita,
Although tafamidis treatment improves prognosis in patients with wild-type transthyretin amyloid cardiomyopathy, an optimal surrogate marker monitoring its therapeutic effect remains unclear. This study investigated the association between changes in cardiac biomarkers, high-sensitivity cardiac troponin T (hs-cTnT) and B-type natriuretic peptide (BNP) during the first year after tafamidis treatment and clinical outcomes.
Tópico(s): Neuroendocrine Tumor Research Advances
2024 - Wiley | Journal of the American Heart Association
Hitoki Nanaura, Honoka Kawamukai, Ayano Fujiwara, Takeru Uehara, Yuichiro Aiba, Mari Nakanishi, T. Shiota, Masaki Hibino, Pattama Wiriyasermkul, Sotaro Kikuchi, Riko Nagata, Masaya Matsubayashi, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Naritaka Morikawa, Naohiko Iguchi, Takao Kiriyama, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Oda T, Noriyuki Kodera, Sachiko Toma-Fukai, Mamoru Sato, Hideki Taguchi, Shushi Nagamori, Osami Shoji, Koichiro Ishimori, Hiroyoshi Matsumura, Kazuma Sugie, Tomohide Saio, Takuya Yoshizawa, Eiichiro Mori,
Abstract Nuclear import receptors (NIRs) not only transport RNA-binding proteins (RBPs) but also modify phase transitions of RBPs by recognizing nuclear localization signals (NLSs). Toxic arginine-rich poly-dipeptides from C9orf72 interact with NIRs and cause nucleocytoplasmic transport deficit. However, the molecular basis for the toxicity of arginine-rich poly-dipeptides toward NIRs function as phase modifiers of RBPs remains unidentified. Here we show that arginine-rich poly-dipeptides impede the ...
Tópico(s): RNA and protein synthesis mechanisms
2021 - Nature Portfolio | Nature Communications
Hiroki Usuku, Eiichiro Yamamoto, Daisuke Sueta, Rumi Shinriki, Fumi Oike, Noriaki Tabata, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, Yuichiro Arima, Seiji Takashio, Yawara Kawano, Seitaro Oda, Hiroaki Kawano, Mitsuharu Ueda, Kenichi Tsujita,
Abstract Aims There are minimal data on the prognostic impact of right atrial strain during the reservoir phase (RASr) in patients with immunoglobulin light‐chain (AL) cardiac amyloidosis. Methods and results Among 78 patients who were diagnosed with AL cardiac amyloidosis at Kumamoto University Hospital from 2007 to 2022, 72 patients with sufficient two‐dimensional speckle tracking imaging data without chemotherapy before the diagnosis were retrospectively analysed. During a median follow‐up of 403 ...
Tópico(s): Cardiovascular Function and Risk Factors
2024 - Wiley | ESC Heart Failure
Tetsuhisa Oda, Eiichiro Takahagi,
Tópico(s): Fuzzy Systems and Optimization
2025 - Japan Society for Fuzzy Theory and Intelligent Informatics | Journal of Japan Society for Fuzzy Theory and Intelligent Informatics