Ana María Abréu Vélez, Michael S. Howard, Zhe Jiao, Weiqing Gao, Hong Yi, Hans E. Grossniklaus, Mauricio Duque-Ramírez, Samuel C. Dudley,
... new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF) have experienced a sudden death syndrome, including persons below the age of 50. El Bagre-EPF patients share several autoantigens with paraneoplastic pemphigus ... autoantibodies to the heart. Therefore, we tested 15 El Bagre-EPF patients and 15 controls from the endemic ... as antigens. We found that 7 of 15 El Bagre patients exhibited a polyclonal immune response to several ... Purkinje fibers, and cardiac sarcomeres. We conclude that El Bagre-EPF patients display autoreactivity to multiple cardiac epitopes, ...
Tópico(s): Urticaria and Related Conditions
2011 - Springer Science+Business Media | Journal of Clinical Immunology
... 25,62% de la población urabaense y El Bagre reunía el 27,2% de la población bajocaucana. El 100% ... en Turbo y 156‰ en el conjunto de El Bagre y Zaragoza. En 2000-septiembre 2003, la relación ... indican: a) Cloroquina (CQ): ha crecido en Zaragoza-El Bagre y en Turbo y en ambos lugares supera el 80%; no debe usarse más ni como monoterapia ...
Tópico(s): Mosquito-borne diseases and control
2004 - Universidad de Antioquia | IATREIA
Ana María Abréu Vélez, Hong Yi, Gunnar Warfvinge, Michael S. Howard,
... new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF).Here we aimed to investigate disease autoreactivity ... autopsies on seven patients who died affected by El Bagre-EPF. We immunoadsorbed any positive vessel immunofluorescence with ... new autoantigens.Overall, 57/57 patients affected by El Bagre-EPF displayed autoantibodies to vessels in all the ...
Tópico(s): Platelet Disorders and Treatments
2017 - Wiley | International Journal of Dermatology
Ana María Abréu Vélez, Michael S. Howard, Marcos Restrepo‐Isaza, Bruce R. Smoller,
... described a new variant of EPF in El Bagre, Colombia, (El Bagre‐EPF). When we examined the skin biopsies from ... a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, South America.
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2009 - Wiley | Journal of Cutaneous Pathology
Ana María Abréu Vélez, Michael S. Howard, Jorge Enrique Velazquez-Velez,
... patients affected by endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF), display autoreactivity to the heart.The purpose ... reviewed.The main ECG abnormalities seen in the El Bagre-EPF patients were sinus bradycardia (in one-half), ... 01).One-third of the patients affected by El Bagre-EPF have rhythm abnormalities that slow the conduction ...
Tópico(s): Urticaria and Related Conditions
2017 - Elsevier BV | Heart Rhythm
Ana María Abréu Vélez, Michael S. Howard, Takashi Hashimoto, Hans E. Grossniklaus,
... endemic pemphigus foliaceus (EPF) in Colombia, South America (El Bagre-EPF). Objective Continuing our characterization of this variant ... tissue. We tested sera from 12 patients with El Bagre-EPF and ocular lesions, 5 patients with sporadic ( ... and 20 healthy control subjects (10 from the El Bagre-EPF endemic area and 10 from nonendemic areas). ... was seen in 10 of 12 of the El Bagre-EPF sera and in one control with pemphigus ... autoantibodies to meibomian glands and tarsal muscle in El Bagre-EPF. Our findings suggest that the autoantibodies to ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2010 - Elsevier BV | Journal of the American Academy of Dermatology
Ana María Abréu Vélez, Michael S. Howard, Hong Yi, Adriana Flórez-Vargas,
... variant of endemic pemphigus foliaceus (EPF) in El Bagre, Colombia (termed El Bagre-EPF or pemphigus Abreu-Manu) have systemic compromise. ... and its pathological correlations.To investigate patients with El Bagre-EPF for renal compromise.We performed a case-control study, enrolling 57 patients with El Bagre-EPF and 57 controls from the endemic area, ... first time that one-third of patients with El Bagre-EPF have polyclonal autoantibodies to kidney. The kidneys ...
Tópico(s): Urticaria and Related Conditions
2018 - Oxford University Press | Clinical and Experimental Dermatology
Ana María Abréu Vélez, Michael S. Howard, Takashi Hashimoto,
... a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, South America (El Bagre-EPF). On physical examination, the palms and soles of El Bagre-EPF patients reveal an edematous texture and mild ... preceding observation, we tested the palms of 20 El Bagre-EPF cases and 20 controls from the endemic ... erosions are clinically observed on the palms of El Bagre-EPF patients, our DIF detected distinct immunoreactivity in ...
Tópico(s): Platelet Disorders and Treatments
2010 - John Libbey Eurotext | European Journal of Dermatology
Ana María Abréu Vélez, Hong Yi, Weiqing Gao, Bruce R. Smoller, Hans E. Grossniklaus, Michael S. Howard,
... with a new variant of endemic pemphigus foliaceus (El Bagre EPF) in South America. We tested for El Bagre EPF patient sera autoreactivity to pilosebaceous units utilizing ... that one third of the patients affected by El Bagre-EPF demonstrated some histologic alteration of the pilosebaceous units. By immunohistochemistry, most El Bagre EPF biopsies demonstrated evidence of an autoimmune response ... the basement membrane area of the sebaceous glands. El Bagre-EPF patients have autoantibodies to pilosebaceous units and ...
Tópico(s): Sympathectomy and Hyperhidrosis Treatments
2011 - John Libbey Eurotext | European Journal of Dermatology
Ana María Abréu Vélez, Takashi Hashimoto, Wendy B. Bollag, Sergio Iván Tobón‐Arroyave, Clara Eugenia Abrèu-Velez, Martha Luz Londoño, Fernando Montoya, Ernst H. Beutner,
... a mining town in northeastern Colombia in the El Bagre area, to characterize it, and to compare it ... immunologic fieldwork case-control survey was performed in El Bagre, Colombia. Results Our work revealed that this disease is endemic in rural areas surrounding El Bagre. The disease appeared in 4.7% of middle- ... Conclusion We have confirmed endemic pemphigus foliaceus in El Bagre as an autoimmune disease that shares features with ...
Tópico(s): Autoimmune Bullous Skin Diseases
2003 - Elsevier BV | Journal of the American Academy of Dermatology
... 11 años) de las poblaciones antioqueñas de Turbo, El Bagre y Zaragoza. Se hace énfasis en las relaciones ... antihelmínticos de amplio espectro. En Turbo y en El Bagre y Zaragoza: 1) la frecuencia de malaria registra ... y 156 casos por cada mil sujetos expuestos (El Bagre-Zaragoza) en 1996-2000; 2) el riesgo de desnutrición crónica (índice talla/ edad) es ...
Tópico(s): Mosquito-borne diseases and control
2004 - Universidad de Antioquia | IATREIA
Ana María Abréu Vélez, Bruce R. Smoller, Weiqing Gao, Hans E. Grossniklaus, Zhe Jiao, Luis Fernando Arias, Samuel C. Dudley, Michael S. Howard,
... by a new variant of endemic pemphigus in El Bagre, Colombia, South America. Case report We describe a ... a new variant of endemic pemphigus foliaceus from El Bagre that was receiving high‐dosage immunosuppressants when hospitalized ... both of them are rich in plakins and El Bagre‐EPF patients present significant antibodies to plakin molecules. ...
Tópico(s): Urticaria and Related Conditions
2012 - Wiley | International Journal of Dermatology
Victoria Tirado, Monica A. Garcia, José Eduardo Moreno, Luz Marina Galeano, Francisco Lopera, A Franco,
... been studied.To determine whether the miners of El Bagre (Antioquia, Columbia) have neuropsychological and/or behavior disorders ... up of 22 right-handed men, residents of El Bagre, aged between 20 and 45 years old who ...
Tópico(s): Medical research and treatments
2000 - Viguera Publishers | Revista de Neurología
J. E MOJICA RODRÍGUEZ, Pablo E. Cruz‐Casallas,
... essays on crioconservation of semen of catfish “lined bagre”.RESUMEN: El bagre rayado (Pseudoplatystoma fasciatum) es un silúrido de las ... superiores a 10% de DMSO son tóxicas para el espermatozoide de bagre rayado y su protocolo de crioconservación requiere aún ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2005 - | Orinoquia
Ana María Abréu Vélez, Yulieth Upegui, Carlos Andres Valencia‐Yepes,
... new variant of endemic pemphigus foliaceus in El Bagre (El Bagre-EPF) (AKA pemphigus Abreu-Manu) and surrounding municipalities. ... range of nail alterations in patients affected by El Bagre-EPF.Methods: A case-controlled study was conducted ...
Tópico(s): Autoimmune Bullous Skin Diseases
2019 - Our Dermatology Online | Our Dermatology Online
Ana María Abréu Vélez, Hong Yi, Paul B. Googe, Martín C. Mihm, Michael S. Howard,
... new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF).Our study was conducted to determine the ... Bielschowsky staining and immunoelectron microscopy studies.In the El Bagre-EPF patients, we detected dermal melanin in melanophages ... engulfing both autoantigens and/or cellular debris in El Bagre-EPF. Autoantibodies to discrete components of melanocytes were ...
Tópico(s): melanin and skin pigmentation
2011 - Wiley | Journal of Cutaneous Pathology
Ana María Abréu Vélez, Michael S. Howard, Hong Yi, Weiqing Gao, Takashi Hashimoto, Hans E. Grossniklaus,
... patients affected by a new variant of EPF (El Bagre-EPF). We tested 20 El Bagre-EPF patients, 20 normal controls from the endemic ...
Tópico(s): Urticaria and Related Conditions
2011 - Springer Science+Business Media | Journal of Clinical Immunology
George D. Kamenov, Jaime Escobar, Tim Arnold, Andrés Pardo‐Trujillo, Gotzon Gangoiti, Natalia Hoyos, Jason H. Curtis, Broxton W. Bird, María I. Vélez, Felipe Vallejo, Raúl Trejos-Tamayo,
... namely San Lucas, San Martin de Loba, and El Bagre, located in north-central Colombia, show low Pb ... area of San-Lucas, San-Martin, and/or El Bagre released Pb in the atmosphere that was transported and deposited in the El Triunfo mire. These deposits are not associated with ...
Tópico(s): Lichen and fungal ecology
2020 - Elsevier BV | Geochimica et Cosmochimica Acta
Silvia Blair, Luis Gonzalo Álvarez, A. Villa Restrepo, Jaime C. Fonseca, Leonardo Alberto Ríos-Osório,
... malaria enColombia: 66 niños de los municipios de El Bagre y Zara-goza (zona de mayor riesgo malárica) ... Colombia. The sample consisted of 66 children from El Bagre and Zaragoza (high transmission area) and 62 children ...
Tópico(s): Parasites and Host Interactions
2003 - Elsevier BV | Anales de Pediatría
Ana María Abréu Vélez, Ernst H. Beutner, Fernando Montoya, Wendy B. Bollag, Takashi Hashimoto,
... of endemic pemphigus foliaceus in rural areas of El Bagre, Colombia, with clinical and direct immunofluorescence characteristics of ... periplakin, respectively. Conclusion This endemic pemphigus disease in El Bagre showed immunologic features similar to pemphigus foliaceus or ...
Tópico(s): Autoimmune Bullous Skin Diseases
2003 - Elsevier BV | Journal of the American Academy of Dermatology
Mary Ann Robledo, C. STEMA PRADA, DIEGO JARAMILLO, Walter León,
... the 'fogo selvagem' type. The patients came from El Bagre and Nechi, rural areas of Colombia with some ...
Tópico(s): Plant and fungal interactions
1988 - Oxford University Press | British Journal of Dermatology
Rosa Magdalena Uscátegui, Adriana María Mejía Correa,
... They resided in the municipalities of Turbo and El Bagre (Antioquia, Colombia) and volunteered for an experimental, study ...
Tópico(s): Iron Metabolism and Disorders
2007 - National Institute of Health | Biomédica
Ana María Abréu Vélez, Yulieth Upegui, Carlos Andres Valencia‐Yepes, Eduardo Upegui‐Quiceño, Natalia‐Regina Mesa‐Herrera, Alejandra Maria Jiménez-Echavarria, César D. N. Pulido, Bruce R. Smoller, Michael S. Howard,
El Bagre endemic pemphigus foliaceus (El Bagre-EPF) is a new variant of endemic pemphigus foliaceus present in the El Bagre area of Colombia, South America. Here, we investigate ... in lesional skin in 43 patients affected by El Bagre-EPF, as well as 43 matched, healthy controls ... in all cases of the patients affected by El Bagre-EPF and was not observed in the controls ... b9 staining (P < 0.001).Patients affected by El Bagre-EPF have lesional deposition of complement/C5b, which ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2019 - Wiley | Journal of Cutaneous Pathology
Carmen Rosa GARCÍA-DÁVILA, Diana CASTRO-RUIZ, Homero Sánchez-Ribeiro, Rosa A. ISMIÑO-ORBE, Dixner Rengifo-Trigoso, Aurea Rosa GARCÍA-VÁSQUEZ, José Salvador Tello-Martín, Werner Chota-Macuyama, Fabrice Duponchelle, Jean‐François Renno,
... de los dos periodos hidrológicos evaluados. Larvas de bagres como el dorado Brachyplatystoma rosseauxii, el saltón B. filamentosum y ... importancia de los ríos de aguas blancas en el mantenimiento del ciclo de vida de estos grandes bagres.
Tópico(s): Fish Ecology and Management Studies
2014 - | Folia Amazónica
Ana María Abréu Vélez, Carlos Andres Valencia‐Yepes, Yulieth Upegui, Eduardo Upegui‐Quiceño, Natalia‐Regina Mesa‐Herrera, Jorge Enrique Velazquez-Velez, Michael S. Howard,
... a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, South America, which we term El Bagre‐EPF, and observed reactivity to arrector pili muscle ( ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2017 - Oxford University Press | Clinical and Experimental Dermatology
Gashaw Tesfaye, Matthias Wolff,
... em>, la carpa<em> Cyprinus carpio </em>y el bagre <em>Clarias gariepinus</em>. El estudio aquí presentado tiene como objetivo determinar estos ... frecuencia de tallas obtenidas de capturas trimestrales en el periodo 2007-2012. Un total de 20 097 especímenes fueron medidos (7 933 de tilapia, 6 025 de bagre y 6 139 de carpa). Los parámetros de ...
Tópico(s): Fish Ecology and Management Studies
2015 - Vicerractoría Investigación | Revista de Biología Tropical
Jorge E. Mario-Vasquez, Carlos Andrés Naranjo-González, Jehidys Montiel, Lina Zuluaga, Ana María Vásquez, Alberto Tobón-Castaño, Gabriel Bedoya, César Segura,
... purpose, the ancestral genetic composition of Turbo and El Bagre was determined. A higher Native American ancestry trend ... Compared to the paisa population (Antioquia), Turbo and El Bagre showed a strong decrease in European ancestry and ...
Tópico(s): Child Nutrition and Water Access
2020 - Elsevier BV | Infection Genetics and Evolution
Luisa Fernanda Gómez Ossa, Verónica Botero,
... vías, como la Variante Porce y la vía El Bagre-San Jacinto del Cauca, en el departamento de Antioquia. El entrenamiento de las RNAs ...
Tópico(s): Wildlife-Road Interactions and Conservation
2017 - National University of Colombia | DYNA
Ana María Abréu Vélez, Michael S. Howard, Hector Jose Lambraño Padilla, Sergio Iván Tobón‐Arroyave,
... a variant of endemic pemphigus foliaceus (EPF) in El Bagre area known as pemphigus Abreu-Manu. Our previous ... by a new variant of endemic pemphigus foliaceus (El Bagre-EPF) demonstrated oral involvement.A case-control study ... for oral changes in 45 patients affected by El Bagre-EPF, as well as 45 epidemiologically matched controls ... were seen in in 43 of the 45 El Bagre-EPF patients and 20 of the 45 controls ( ... Hematoxylin and eosin staining showed 23 of 45 El Bagre-EPF patients had corneal/subcorneal blistering and lymphohistiocytic ...
Tópico(s): Platelet Disorders and Treatments
2018 - | Dermatology Practical & Conceptual
Felipe Vázquez, Tomás R. Florville-Alejandre, Miguel Herrera, Luz María Díaz de León,
... contenido de metales pesados en tejido muscular del bagre, Ariopsis felis en el sur del golfo de México durante el período 2001-2004.La investigación fue efectuada buscando ...
Tópico(s): Mercury impact and mitigation studies
2008 - Escuela de Ciencias del Mar, Facultad de Recursos Naturales, Pontificia Universidad Católica de Valparaíso | Latin American Journal of Aquatic Research