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Andrew Robson, Geoff Bard, Lucy Alexander, Gerald Stonehill, John Grieve Smith, Fred Redwood, David Brown, Zahid Hussain, Professor Alan Malcolm, Greg Hurst Political Correspondent, Frances Gibb Legal Editor, Gary Duncan, Simon Barnes, Amanda Ursell, Robert Lindsay, Mark Souster, David Rose, Jane Bennett, Director of Vision, Alexandra Frean Education Editor, Caroline Brannigan, Mark Byford, deputy director-general, Philip Howard, Christine Seib, James Ducker, Lorna Blackwood, Elizabeth Judge, Carl Mortished, Martin Shuttleworth, John Wayman, Jenny Knight, Jeremy Whittle, Kevin Eason, Geoff Brown, Andrew Norfolk, Ben Webster Transport Correspondent, AndrÉe Deane, John Clarke, Rob Crilly, Jack Malvern, Dominic Walsh, Tom Bawden, Rachel Holmes, Debra Craine, Tim Reid, Dan Sabbagh, Libby Purves, Alan Hamilton, Dr Peter Cotgreave, David Kelsall, Nick Wyke, Tom Harris, MP, Keith Hayday, Rhys Blakely, Dr Edmund Nickless, Charles Bremner, Ron Lewis, Guillem Balague, Adam Sherwin Media Correspondent, Matt Dickinson Chief Football Correspondent, David Charter, Tim Teeman, Hugo Rifkind, Derwent May, Tony Whitfield, Ann Tyas, Russell Kempson, Paula Hawkins, Simon Midgley, Gerard Baker, Russell Vallance, Mark Henderson Science Editor, James Harding Business Editor, Tom Baldwin, James Rossiter, P. C. Doherty, Jill Sherman Whitehall Editor, Sam Coates, David Lawrenson, Dr Richard Pike Chief Executive, Ann Treneman, Simon de Bruxelles, John Hopkins Golf Correspondent, Rob Wright, Philip Banham, Bernard Lagan, David chater, Marcus Binney, Raymond Keene, Lucia Adams, Matthew Pryor, Matt Hughes, Sally Heaton, Francis Elliott Chief Political Correspondent, Nicholas Tucker, Kaveh Solhekol, John Hayward, Chris Campling, Fran Yeoman, Peter Neufeld, Maria Elena Cherchi, Patrick Hosking, Hattie Garlick, Tristan McConnell, Lindsey Bareham, Kay Bagon, Mick Hume, Roger Boyes, David Mattin, Nick Hasell, Anne Fine, Dr Robert Kirby-Harris, Dalya Alberge, Paul Simons, Helen Boaden, Director of News, Adam Fresco, Steve Jelbert, Anne Ashworth, Dearbáil Jordan, Peter Burville, Andrew Martin, Philip Webster Political Editor, Philip Roberts, Steve Hawkes, Michele Kirsch, Thomas Catán, Dominic Maxwell, Alison Forster Managing Director, Simon Callow, John Hodgkin, Russell Jenkins, Neil Fisher, Peter Riddell, Ben MacIntyre, D. B. Welbourn, Oliver Dowding, Melanie McDonagh, Jan Dorset, Nick Beeson, Tom Hennigan, Peter Jenson, David Sanderson, Jamie Whyte, Martin Waller, Melvyn Carter, Mark Loveday, Pierre Tran, Patrick Foster, Dr Hillary J. Shaw, Ashling O'Connor, Angus Batey, Stuart Birch, Margaret Warbis, Sam Coates Political Correspondent, Stephen Dalton, Nicola Woolcock, Leo Lewis, Peter Plumridge, Richard Morrison, Frances Gibb, Michael Oatley, Peter Burley, Judith Heywood, Alan Lee Racing Correspondent, Olav Bjortomt, Conal Gregory, Miles Costello, David Robertson, Catherine Riley Motoring Editor, Lisa Verrico, Elizabeth Judge Telecoms Correspondent, Susan Emmett,

... aims for adjustment in attitude to boost career Torres 'made up' to join club who could have ... loan deal The Times From Madrid to Merseyside: Torres aims to be the new … Motor racing Simon ...

2007 - Gale Group | TDA

Errata Acesso aberto Revisado por pares

Neibla Priego, Lucía Zhu, Cátia Monteiro, Manon Mulders, David Wasilewski, Wendy Bindeman, Laura Doglio, Liliana Galbis Martínez, Elena Martínez‐Sáez, Santiago Ramón y Cajal, Diego Megı́as, Elena Hernández-Encinas, Carmen Blanco‐Aparicio, Lola Martínez, Eduardo Zarzuela, Javier Muñoz, Coral Fustero‐Torre, Elena Piñeiro-Yáñez, Aurelio Hernández‐Laín, Luca Bertero, Valeria Poli, Melchor Sánchez-Martínez, Javier A. Menéndez, Riccardo Soffietti, Joaquím Bosch-Barrera, Manuel Valiente,

... incorrect. The authors were listed as “Coral Fustero-Torres”, “Elena Pineiro” and “Melchor Sánchez-Martínez”. Their respective names are “Coral Fustero-Torre”, “Elena Piñeiro-Yáñez” and “Melchor Sanchez-Martinez”. The errors ...

Tópico(s): Chemical Reactions and Isotopes

2018 - Nature Portfolio | Nature Medicine

Artigo Revisado por pares

Antonio Gasbarrini, Veronica Ojetti, Dario Pitocco, Francesco Franceschi, Marcello Candelli, Elena Torre, Maurizio Gabrielli, Giovanni Cammarota, Alessandro Armuzzi, Roberto Pola, Paolo Pola, Giovanni Ghirlanda, Antonio Gasbarrini,

... Ojetti, Veronicab; Pitocco, Darioc; Franceschi, Francescob; Candelli, Marcellob; Torre, Elena Sanzb; Gabrielli, Mauriziob; Cammarota, Giovannib; Armuzzi, Alessandrob; Pola, ...

Tópico(s): Eosinophilic Esophagitis

1999 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology

Artigo Acesso aberto Revisado por pares

Manuel Guthmann, Adam Burton, Maria‐Elena Torres‐Padilla,

... Search for more papers by this author Maria-Elena Torres-Padilla Corresponding Author Maria-Elena Torres-Padilla [email protected] orcid.org/0000-0002-1020- ... Search for more papers by this author Maria-Elena Torres-Padilla Corresponding Author Maria-Elena Torres-Padilla [email protected] orcid.org/0000-0002-1020- ... Manuel Guthmann1,2, Adam Burton1,2 and Maria-Elena Torres-Padilla *,1,2 1Institute of Epigenetics and Stem ...

Tópico(s): RNA modifications and cancer

2019 - Springer Nature | EMBO Reports

Artigo Acesso aberto Revisado por pares

Maria‐Elena Torres‐Padilla, Annelien L. Bredenoord, Karin Jongsma, Astrid Lunkes, Luca Marelli, Inês Pinheiro, Giuseppe Testa,

... an international, cross-disciplinary biomedical research consortium Maria-Elena Torres-Padilla Corresponding Author Maria-Elena Torres-Padilla [email protected] orcid.org/0000-0002-1020- ... Search for more papers by this author Maria-Elena Torres-Padilla Corresponding Author Maria-Elena Torres-Padilla [email protected] orcid.org/0000-0002-1020- ... more papers by this author Author Information Maria-Elena Torres-Padilla *,1,2, Annelien L Bredenoord3, Karin R ...

Tópico(s): Ethics in Clinical Research

2020 - Springer Nature | The EMBO Journal

Artigo Revisado por pares

P Mezquita, Victor M. Luna, Manuel Muñoz‐Torres, Elena Torres‐Vela, Fernando López Rodríguez, José Luis Callejas‐Rubio, F. Escobar‐Jiménez,

The major adverse reactions of antithyroid drugs are hematologic; aplastic anemia (AA) is one of the rarest and most severe complications. Use of recombinant human hemopoietic colony-stimulating factor was reported to be of benefit in patients who developed agranulocytosis, although there is still some doubt regarding the efficacy in AA. We present a case of a 58-year-old female patient with Graves' disease who developed AA in the third exposure to methimazole (MMI). The withdrawal of MMI and early ...

Tópico(s): Hematological disorders and diagnostics

1998 - Mary Ann Liebert, Inc. | Thyroid

Artigo Acesso aberto Revisado por pares

Roberta Noberini, Elena Rubio de la Torre, Elena B. Pasquale,

The Eph receptor tyrosine kinase family includes many members, which are often expressed together in various combinations and can promiscuously interact with multiple ephrin ligands, generating intricate networks of intracellular signals that control physiological and pathological processes. Knowing the entire repertoire of Eph receptors and ephrins expressed in a biological sample is important when studying their biological roles. Moreover, given the correlation between Eph receptor/ephrin expression ...

Tópico(s): Neuroscience and Neuropharmacology Research

2012 - Landes Bioscience | Cell Adhesion & Migration

Artigo Acesso aberto Revisado por pares

María Palomares‐Bralo, Alicia Delicado, Elena Mansilla, María Torres, Elena Vallespín, Luís Fernández, Victor Martínez‐Glez, Sixto García‐Miñaúr, Julián Nevado, Fernando Santos‐Simarro, Víctor L. Ruiz‐Pérez, Sally Ann Lynch, Freddie H. Sharkey, Ann‐Charlotte Thuresson, Göran Annerén, Elga Fabia Belligni, M.L. Martínez‐Fernández, Eva Bermejo, Beata Nowakowska, Anna Kutkowska‐Kaźmierczak, Ewa Bocian, Ewa Obersztyn, María Luisa Martínez‐Frías, Raoul C. M. Hennekam, Pablo Lapunzina,

We report eight unrelated individuals with intellectual disability and overlapping submicroscopic deletions of 8q21.11 (0.66–13.55 Mb in size). The deletion was familial in one and simplex in seven individuals. The phenotype was remarkably similar and consisted of a round face with full cheeks, a high forehead, ptosis, cornea opacities, an underdeveloped alae, a short philtrum, a cupid's bow of the upper lip, down-turned corners of the mouth, micrognathia, low-set and prominent ears, and mild finger ...

Tópico(s): Congenital heart defects research

2011 - Elsevier BV | The American Journal of Human Genetics

Artigo Acesso aberto Revisado por pares

Elma Montaña, Laura Torres, Elena M. Abraham, Eduardo Torres, Gabriela Claudia Pastor,

En el presente trabajo se analiza el proceso de configuración territorial de Mendoza, Argentina, representativo de otros pertenecientes a tierras secas de América Latina, en el marco de la concepción de las "nuevas periferias" asociadas a la reestructuración de las economías. La fragmentación territorial actual sería el producto de una misma lógica que, mientras concentra recursos, población y poder en una pequeña porción del territorio -los oasis irrigados-, lo hace a costa del despojo o agotamiento ...

Tópico(s): Latin American rural development

2005 - El Colegio de Sonora | región y sociedad

Artigo Revisado por pares

Rosa M. Claramunt, Pilar Cornago, Verónica Torres, Elena Pinilla, M.R. Torres, André Samat, Vladimir Lokshin, M. Valès, José Elguero,

The structures of six N-unsubstituted pyrazoles, three already known and three newly synthesized, have been studied by a combination of X-ray crystallography, multinuclear NMR (solution and solid state), and density functional theory (DFT) calculations. In those cases where crystal structure and CPMAS NMR were available, the agreement was almost perfect, allowing a prediction of the tautomer (with certitude) and the tetrameric structure (with high probability) in the case of 5-isopropyl-3-phenyl-1H- ...

Tópico(s): Chemical Thermodynamics and Molecular Structure

2006 - American Chemical Society | The Journal of Organic Chemistry

Artigo Revisado por pares

Rosa M. Claramunt, Pilar Cornago, Dolores Santa María, Verónica Torres, Elena Pinilla, M.R. Torres, José Elguero,

The X-ray structure and the solid-state NMR measurements, mainly 15N CPMAS of the labelled compound, allow to determine the static and dynamic properties of 3(5)-ethyl-5(3)-phenyl-1H-pyrazole. The compound is a tetramer formed by three 5-ethyl-3-phenyl-1H-pyrazole and one 3-ethyl-5-phenyl-1H-pyrazole tautomers in dynamic equilibrium with the complementary situation.

Tópico(s): Coordination Chemistry and Organometallics

2006 - Taylor & Francis | Supramolecular chemistry

Revisão Acesso aberto Revisado por pares

Xavier Gaume, Maria‐Elena Torres‐Padilla,

Xavier Gaume and Maria-Elena Torres-Padilla Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM U964, U de S, F-67404 Illkirch, CU ...

Tópico(s): CRISPR and Genetic Engineering

2015 - Cold Spring Harbor Laboratory Press | Cold Spring Harbor Symposia on Quantitative Biology

Artigo Acesso aberto Revisado por pares

Carlés Subirá, Gonzalo Hernández, Antònia Vázquez, Raquel Rodríguez-García, A. González-Castro, Carolina García, Olga Rubio, Lara Ventura, Alexandra López, Maria-Carmen de la Torre, Elena Keough, Vanesa Arauzo, Cecilia Hermosa, Carmen Sánchez‐Torres, Ana Isabel Tizón, Eva María Olivares Tenza, César Laborda, Sara Cabañes, Victoria Lacueva, Mar Fernández‐Gutiérrez, Anna Arnau, Rafael Fernández,

Importance Daily spontaneous breathing trials (SBTs) are the best approach to determine whether patients are ready for disconnection from mechanical ventilation, but mode and duration of SBT remain controversial. Objective To evaluate the effect of an SBT consisting of 30 minutes of pressure support ventilation (an approach that is less demanding for patients) vs an SBT consisting of 2 hours of T-piece ventilation (an approach that is more demanding for patients) on rates of successful extubation. Design, Setting, ...

Tópico(s): Intensive Care Unit Cognitive Disorders

2019 - American Medical Association | JAMA

Artigo Acesso aberto Revisado por pares

Dolores Hernán Pérez de la Ossa, Mar Lorente, María Esther Gil-Alegre, Sofía Torres, Elena García-Taboada, M.R. Aberturas, Jesús Molpeceres, Guillermo Velasco, Ana Isabel Torres‐Suárez,

Cannabinoids, the active components of marijuana and their derivatives, are currently investigated due to their potential therapeutic application for the management of many different diseases, including cancer. Specifically, Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) – the two major ingredients of marijuana – have been shown to inhibit tumor growth in a number of animal models of cancer, including glioma. Although there are several pharmaceutical preparations that permit the oral administration ...

Tópico(s): Sleep and Wakefulness Research

2013 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Revisado por pares

Neibla Priego, Lucía Zhu, Cátia Monteiro, Manon Mulders, David Wasilewski, Wendy Bindeman, Laura Doglio, Liliana Galbis Martínez, Elena Martínez‐Sáez, Santiago Ramón y Cajal, Diego Megı́as, Elena Hernández-Encinas, Carmen Blanco‐Aparicio, Lola Martínez, Eduardo Zarzuela, Javier Muñoz, Coral Fustero‐Torre, Elena Piñeiro-Yáñez, Aurelio Hernández‐Laín, Luca Bertero, Valeria Poli, Melchor Sánchez-Martínez, Javier A. Menéndez, Riccardo Soffietti, Joaquím Bosch-Barrera, Manuel Valiente,

The brain microenvironment imposes a particularly intense selective pressure on metastasis-initiating cells, but successful metastases bypass this control through mechanisms that are poorly understood. Reactive astrocytes are key components of this microenvironment that confine brain metastasis without infiltrating the lesion. Here, we describe that brain metastatic cells induce and maintain the co-option of a pro-metastatic program driven by signal transducer and activator of transcription 3 (STAT3) ...

Tópico(s): Brain Metastases and Treatment

2018 - Nature Portfolio | Nature Medicine

Artigo Acesso aberto Revisado por pares

Jordi Riera, Enric Barbeta, Adrián Tormos, Ricard Mellado‐Artigas, Adrián Ceccato, Ana Motos, Laia Fernández‐Barat, Ricard Ferrer, Dario García-Gasulla, Óscar Peñuelas, José Ángel Lorente, Rosario Menéndez, Oriol Roca, Andrea Palomeque, Carlos Ferrando, Jordi Solé‐Violán, Mariana Andrea Novo, María Victoria Boado, Luís Tamayo, Ángel Estella, Cristobal Galbán‐Malagón, Josep Trenado, Arturo Huerta, Ana Loza, Luciano Aguilera, J.L. García Garmendia, Carme Barberà, Víctor Gumucio, Lorenzo Socías, Nieves Franco, Luis Jorge Valdivia, Pablo Vidal, Víctor Sagredo-Meneses, Ángela Leonor Ruiz-García, Ignacio Martínez Varela, Juan López, Juan Carlos Pozo Laderas, Maite Nieto, José M. Gómez, Aarón Blandino, M. Valledor, Elena Bustamante‐Munguira, Ángel Sánchez-Miralles, Yhivian Peñasco, José Barberán, Alejandro Úbeda, Rosario Amaya-Villar, M.C. Martín Delgado, Ruth Jorge, Jesús Caballero, Judith Marin, José M. Añón, Fernando Suárez-Sipmann, Guillermo M. Albaiceta, Álvaro Castellanos-Ortega, Berta Adell-Serrano, M. Catalán, Amalia Martínez de la Gándara, Pilar Ricart, Cristina Carbajales, Alejandro Rodríguez, Emili Dı́az, Mari C. de la Torre, Elena Gallego, Luisa Cantón-Bulnes, Nieves Carbonell, Jessica González, David de Gonzalo-Calvo, Ferrán Barbé, Antoní Torres,

The primary aim of our study was to investigate the association between intubation timing and hospital mortality in critically ill patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure. We also analysed both the impact of such timing throughout the first four pandemic waves and the influence of prior noninvasive respiratory support on outcomes.This is a secondary analysis of a multicentre, observational and prospective cohort study that included all consecutive patients ...

Tópico(s): Family and Patient Care in Intensive Care Units

2022 - European Respiratory Society | European Respiratory Journal

Artigo Revisado por pares

Eva Morales, Maria V. Alcantara‐Lopez, Juan Cabezas‐Herrera, Teresa De Diego, Trinidad Hernández‐Caselles, Pedro Jiménez‐Guerrero, Elvira Larqué, Concepción López Soler, Carmen Martínez‐Graciá, Antonela Martínez-Torres, Elena Martín‐Orozco, Jaime Mendiola, Aníbal Nieto Díaz, José Antonio Noguera Velasco, Virginia Pérez‐Fernández, María T. Prieto‐Sánchez, Carme Salvador-García, Manuel Sánchez‐Solís, Marina Santaella, Rosa Alba Sola Martínez, Alberto M. Torres‐Cantero, Genoveva Yagüe‐Guirao, Matilde Zornoza‐Moreno, Luis García‐Marcos,

Abstract Background Primary prevention strategies for asthma are lacking. Its inception probably starts in utero and/or during the early postnatal period as the developmental origins of health and disease (DOHaD) paradigm suggests. Objectives The main objective of Nutrition in Early Life and Asthma (NELA) cohort study is to unravel whether the following factors contribute causally to the developmental origins of asthma: (1) maternal obesity/adiposity and foetal growth; (2) maternal and child nutrition; ( ...

Tópico(s): Birth, Development, and Health

2021 - Wiley | Paediatric and Perinatal Epidemiology

Artigo Acesso aberto Revisado por pares

Carlos Martínez-Torres, Elena Romano, Miguel Layrisse,

Tópico(s): Plant Micronutrient Interactions and Effects

1981 - Elsevier BV | American Journal of Clinical Nutrition

Artigo Revisado por pares

GM Cruz, Higinia R. Cárdenes, J. Otero, I. Millán, Alejandro de la Torre, Elena Simón Polo, F. Valcárcel, M. Cabanillas Paredes,

A multivariate analysis of the prognostic factors for clinical Stages I and II supradiaphragmatic Hodgkin's disease was carried out with a logistic regression model in 341 patients. The proportion of patients with positive staging laparotomy was greater in males, in individuals with several sites involved, mixed cellularity (MC) or lymphocyte depletion (LD) histologic types, systemic symptoms, or in patients with lower cervical involvement and higher erythrocyte sedimentation rate (ESR), serum copper, ...

Tópico(s): Chronic Lymphocytic Leukemia Research

1990 - Wiley | Cancer

Artigo Revisado por pares

Maria del Mar Sanchez Duque, Pelayo Camps, Eva Torres, Elena Valverde, Francesc X. Sureda, Marta López-Querol, Antoni Camins, S. Radhika Prathalingam, John M. Kelly, Santiago Vázquez,

The synthesis of several (1,2,3,5,6,7-hexahydro-1,5:3,7-dimethano-4-benzoxonin-3-yl)amines and related compounds is reported. Several of them display very similar activity to memantine as NMDA receptor antagonists. Several derivatives showed a significant level of trypanocidal activity.

Tópico(s): Pharmacological Receptor Mechanisms and Effects

2009 - Elsevier BV | Bioorganic & Medicinal Chemistry

Revisão Acesso aberto Revisado por pares

José A. G. Agúndez, Carmen Martínez, Dolores Pérez‐Sala, Miguel Carballo, Marı́a José Torres, Elena García‐Martín,

Polymorphisms in drug-related enzymes and receptors are often strongly related to altered drug response and to the risk of developing drug intolerance. Aspirin, usually available as an over-the-counter drug, is one of the most used drugs worldwide and is a common cause of drug intolerance events. Aspirin undergoes polymorphic metabolism. Among the enzymes involved in aspirin biodisposition a major role is played by the enzymes UDP-glucuronosyltransferase UGT1A6, cytochrome P450 CYP2C9 and the xenobiotic/ ...

Tópico(s): Hepatitis C virus research

2009 - Bentham Science Publishers | Current Drug Metabolism

Artigo Acesso aberto Revisado por pares

Mercedes Ingelmo‐Torres, Elena González‐Moreno, Adam Kassan, Michael Hanzal‐Bayer, Francesc Tebar, Albert Herms, Thomas Grewal, John F. Hancock, Carlos Enrich, Marta Bosch, Steven P. Gross, Robert G. Parton, Albert Pol,

In recent years, progress in the study of the lateral organization of the plasma membrane has led to the proposal that mammalian cells use two different organelles to store lipids: intracellular lipid droplets (LDs) and plasma membrane caveolae. Experimental evidence suggests that caveolin (CAV) may act as a sensitive lipid‐organizing molecule that physically connects these two lipid‐storing organelles. Here, we determine the sequences necessary for efficient sorting of CAV to LDs. We show that targeting ...

Tópico(s): Lipid metabolism and disorders

2009 - Wiley | Traffic

Artigo Acesso aberto Revisado por pares

Víctor Peralta, Lucía Moreno-Izco, Ana M. Sánchez-Torres, Elena García de Jalón, María Campos, Manuel J. Cuesta,

This study aimed to characterize the deficit syndrome in drug-naive schizophrenia patients and to examine the relationship between deficit features and primary neurological abnormalities. Drug-naive schizophrenia patients (n = 102) were examined at baseline for demographics, premorbid functioning, duration of untreated illness (DUI), psychopathology, neurological signs, and deficit symptoms, and reassessed at 1-year follow-up. Neurological abnormalities were examined before inception of antipsychotic ...

Tópico(s): Neurological disorders and treatments

2012 - Oxford University Press | Schizophrenia Bulletin

Artigo Acesso aberto Revisado por pares

Enza Lonardo, Patrick Hermann, M Mueller, Stephan M. Huber, Anamaria Balic, Irene Miranda‐Lorenzo, Sladjana Zagorac, Sonia Alcalá, Iker Rodríguez-Arabaolaza, Juan Carlos Ramírez, Raúl Torres, Elena Cano García, Manuel Hidaldo, David Cebrián, Rainer Heuchel, Matthias Löhr, Frank Berger, Peter Bartenstein, Alexandra Aicher, Christopher Heeschen,

(Cell Stem Cell 9, 433–446, November 4, 2011) The supplemental information file originally published with this article inadvertently showed Figure S6 in the place of Figure S4. A corrected version has now been posted online in its place. We apologize for any confusion caused. Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug TherapyLonardo et al.Cell Stem CellNovember 04, 2011In BriefNodal and Activin belong to ...

Tópico(s): Cancer Research and Treatments

2012 - Elsevier BV | Cell stem cell

Artigo Revisado por pares

Florian H. Dalla Torre, Elena V. Pereloma, C.H.J. Davies,

The work hardening rate, strain rate sensitivity and the apparent activation volume of copper processed by equal channel angular extrusion (ECAE) for 1–16 passes are investigated. Constant strain rate and strain rate jump tests performed in compression up to 30% of strain reveal stage III and IV work hardening for specimens subjected to less than 4 passes of ECAE, while specimens subjected to more than 4 passes show the additional occurrence of stage V work hardening. The length scale deduced from ...

Tópico(s): Fusion materials and technologies

2005 - Elsevier BV | Acta Materialia

Artigo Revisado por pares

Kimberly Chu, Eric Ho, Ludwika de la Torre, Elena R. Vasilescu, Charles C. Marboe,

Quilty lesions are mononuclear cell infiltrates identified in human heart transplant biopsies. The biologic significance of Quilty lesions remains undetermined. We monitored acute rejection by biopsy and lymphocyte growth assay (LGA) as well as transplant-related coronary artery disease (TRCAD) by yearly angiogram in 285 recipients of primary heart allografts. Patients showing Quilty lesions on biopsies during the first year posttransplant were compared with patients without such lesions. Recipients' ...

Tópico(s): Renal Transplantation Outcomes and Treatments

2005 - Elsevier BV | Cardiovascular Pathology

Artigo Revisado por pares

Mara Lucia Stecchini, Manuela Del Torre, Elena Venir, Alessia Morettin, Patrizia Furlan, Enrico Maltini,

Thermal properties of dried spores of Bacillus subtilis, investigated by differential scanning calorimetry (DSC), were studied. A reversible heat capacity shift ascribable to glass–rubber transition was observed at 90–115 °C. The transition was found to be a pressure-inhibited volume-activated event. The decoated spores and the extracted peptidoglycan material exhibited glass transition, suggesting that the cortex could be involved in the event. Furthermore, the glass transition was evident when spores ...

Tópico(s): Biofield Effects and Biophysics

2005 - Elsevier BV | International Journal of Food Microbiology

Artigo Acesso aberto Revisado por pares

Tea Restuccia, Beatriz Gómez‐Ansón, Mónica Guevara, Carlo Alessandria, Aldo Torre, Elena M. Alayrach, Carlos Terra, Marta Martı́n, Magda Castellvı́, Lorena Rami, Á.Guttiérez Sáinz, Pere Ginés, Vicente Arroyo,

In advanced cirrhosis there is a reduction in the brain concentration of many organic osmolytes, particularly myo-inositol (MI). Hyponatremia could theoretically aggravate these changes as a result of hypo-osmolality of the extracellular fluid. The aim of this study was to determine the effects of hyponatremia on brain organic osmolytes and brain water content in cirrhosis. Brain organic osmolytes, measured by 1 H-magnetic resonance spectroscopy, and brain water content, as estimated by magnetization ...

Tópico(s): Diet and metabolism studies

2004 - Lippincott Williams & Wilkins | Hepatology

Revisão Revisado por pares

Giuseppe Martucciello, Michele Torre, Elena Belloni, Margherita Lerone, Alessio Pini Prato, Alessandro Cama, Vincenzo Jasonni,

Background/purpose The Currarino syndrome (CS) is a peculiar form of caudal regression syndrome (CRS) characterized by the association of hemisacrum, anorectal malformation (ARM), and presacral mass. The authors analyzed retrospectively their series, and they propose a multidisciplinary diagnostic and therapuetic protocol that until now has not been introduced. Methods A series of 6 patients with CS is presented. Five of them were treated initially in other centers. None of them had an early diagnosis. ...

Tópico(s): Teratomas and Epidermoid Cysts

2004 - Elsevier BV | Journal of Pediatric Surgery

Artigo Acesso aberto Revisado por pares

Emanuel Della‐Torre, Elena Criscuolo, Marco Lanzillotta, Massimo Locatelli, Nicola Clementi, Nicasio Mancini, Lorenzo Dagna,

Spatiotemporal dynamics of interleukin (IL)-6 expression in lymphoid organs influence the balance between antiviral humoral and cellular adaptive immunity.1De Giovanni M Cutillo V Giladi A et al.Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells.Nat Immunol. 2020; 21: 321-330Crossref PubMed Scopus (57) Google Scholar In particular, cytopathic viruses typically induce IL-6-mediated differentiation of naive CD4+ T cells into follicular helper ...

Tópico(s): Long-Term Effects of COVID-19

2021 - Elsevier BV | The Lancet Rheumatology