D. Silvestre, Emilia Ferrer, J. Gayá, E. Jareñ, María Miranda, María Muriach, F. J. P. Romero,
Available lysine content is an indicator of protein quality and nutritional value of milk. Many studies have examined the effects of extraction, treatment and storage of human milk upon its components, though no references are found regarding the possible changes in milk quality as defined by its content in essential amino acids such as lysine. The present study investigates the available lysine content in human milk and the variations in lysine resulting from milk manipulation as follows: (a) Cold ...
Tópico(s): Digestive system and related health
2006 - Wiley | BioFactors
Clara Silvestre, Emilia Di Pace, Roberto Napolitano, Beniamino Pirozzi, G. Cesario,
Journal of Polymer Science Part B: Polymer PhysicsVolume 39, Issue 4 p. 415-424 Article Crystallization, morphology, and thermal behavior of poly(p-phenylene sulfide) C. Silvestre, Corresponding Author C. Silvestre [email protected] Istituto di Ricerca e Tecnologia delle Materie Plastiche, CNR, via Toiano, 6 80072 Arco Felice (Naples), ItalyIstituto di Ricerca e Tecnologia delle Materie Plastiche, CNR, via Toiano, 6 80072 Arco Felice (Naples), ItalySearch for more papers by this authorE. Di Pace, E. ...
Tópico(s): Fiber-reinforced polymer composites
2001 - Wiley | Journal of Polymer Science Part B Polymer Physics
Matthew B. Moyer, Anthony J. Silvestre, Emilia Lombardi, Christopher A. Taylor,
Abstract Concerned about reports of a 15% decline in HIV testing among high-risk youth in an earlier study in Pittsburgh, this study was initiated to explore reasons why young people are not getting tested for HIV, while gathering data on their respective level of risk taking behaviors. A total of 580 surveys were collected from youth aged between 14 and 24. Overall, 17% of youth were found to be at high to some risk for HIV infection, while many of them agreed they were not at-risk for HIV. Young ...
Tópico(s): HIV, Drug Use, Sexual Risk
2007 - Haworth Press | Journal of HIV/AIDS Prevention in Children & Youth
Clara Silvestre, Emilia Di Pace, Sossio Cimmino,
Tópico(s): Rheology and Fluid Dynamics Studies
2000 - CRC Press | Plastics engineering
Clara Silvestre, MariaLaura Di Lorenzo, Emilia Di Pace,
Tópico(s): biodegradable polymer synthesis and properties
2000 - CRC Press | Plastics engineering
Peter von Dadelszen, Zulfiqar A Bhutta, Sumedha Sharma, Jeffrey N. Bone, Joel Singer, Hubert Wong, Mrutyunjaya Bellad, Shivaprasad S. Goudar, Tang Lee, Jing Li, Ashalata Mallapur, Khátia Munguambe, Beth A. Payne, Rahat Qureshi, Charfudin Sacoor, Esperança Sevene, Marianne Vidler, Laura A. Magee, Eusébio Macete, Helena Boene, Felizarda Amose, Orvalho Augusto, Cassimo Bique, Ana Ilda Biz, Rogério Chiaú, Silvestre Cutana, Paulo Filimone, Emília Gonçálves, Marta Macamo, Salésio Macuácua, Sónia Maculuve, Ernesto Mandlate, Analisa Matavele, Jeffrey N. Bone, Dulce Mulungo, Zefanias Nhamirre, Ariel Nhancolo, Cláudio Nkumbula, Vivalde Nobela, Rosa Pires, Corsino Tchavana, Anifa Valá, Faustino Vilanculo, Sana Sheikh, Zahra Hoodbhoy, Imran Ahmed, Amjad Hussain, Javed Memon, Farrukh Raza, Geetanjali Katageri, Umesh Charantimath, Shashidhar G Bannale, Keval S Chougala, Vaibhav B Dhamanekar, Narayan V Honnungar, Anjali Joshi, Namdev A Kamble, Chandrappa C Karadiguddi, Avinash Kavi, Gudadayya S Kengapur, Bhalachandra S. Kodkany, Uday S Kudachi, Sphoorthi S Mastiholi, Geetanjali I Mungarwadi, Umesh Y Ramdurg, Amit Revankar, Sharla Drebit, Dustin Dunsmuir, Chirag Kariya, Mansun Lui, Diane Sawchuck, Domena K. Tu, Ugochi V Ukah, Mai‐Lei Woo Kinshella, J. Mark Ansermino, Ana Pilar Betrán, Richard J. Derman, Shafik Dharamsi, France Donnay, Guy A. Dumont, Susheela Engelbrecht, Veronique Fillipi, Tabassum Firoz, William A. Grobman, Marian Knight, Ana Langer, Simon Lewin, Gwyneth Lewis, Craig Mitton, Nadine Schuurman, Andrew Shennan, Jim Thornton, Olalekan O. Adetoro, John Sotunsa,
BackgroundTo overcome the three delays in triage, transport and treatment that underlie adverse pregnancy outcomes, we aimed to reduce all-cause adverse outcomes with community-level interventions targeting women with pregnancy hypertension in three low-income countries.MethodsIn this individual participant-level meta-analysis, we de-identified and pooled data from the Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomised controlled trials in Mozambique, Pakistan, and India, which ...
Tópico(s): Birth, Development, and Health
2020 - Elsevier BV | The Lancet
Icaro Silvestre Freitas Gomes, Yannick Pérez, Emilia Suomalainen,
The decarbonization of both power and mobility sectors are two main goals established during international environmental summits. Distributed battery storage, such as electric vehicles batteries and stationary ones, ranging from around a dozen to a few hundred kWh and photovoltaic (PV) systems are disruptive technologies not only because they can individually contribute to CO2 emissions reduction but also due to the positive synergies between them. Batteries can store electricity surplus produced ...
Tópico(s): Green IT and Sustainability
2020 - Elsevier BV | Renewable and Sustainable Energy Reviews
Icaro Silvestre Freitas Gomes, Yannick Pérez, Emilia Suomalainen,
Tópico(s): Advanced Battery Technologies Research
2021 - Elsevier BV | Energy Economics
Jeffrey N. Bone, Mrutyunjaya Bellad, Shivaprasad S. Goudar, Ashalata Mallapur, Umesh Charantimath, Umesh Y Ramadurg, Geetanjali Katageri, Maria Lesperance, Mai‐Lei Woo Kinshella, Raiya Suleman, Marianne Vidler, Sumedha Sharma, Richard J. Derman, Laura A. Magee, Peter von Dadelszen, Shashidhar G Bannale, Keval S Chougala, Vaibhav B Dhamanekar, Anjali Joshi, Namdev A Kamble, Gudadayya S Kengapur, Uday S Kudachi, Sphoorthi S Mastiholi, Geetanjali I Mungarwadi, Esperança Sevene, Khátia Munguambe, Charfudin Sacoor, Eusébio Macete, Helena Boene, Felizarda Amose, Orvalho Augusto, Cassimo Bique, Ana Ilda Biz, Rogério Chiaú, Silvestre Cutana, Paulo Filimone, Emília Gonçálves, Marta Macamo, Salésio Macuácua, Sónia Maculuve, Ernesto Mandlate, Analisa Matavele, Sibone Mocumbi, Dulce Mulungo, Zefanias Nhamirre, Ariel Nhancolo, Cláudio Nkumbula, Vivalde Nobela, Rosa Pires, Corsino Tchavana, Anifa Valá, Faustino Vilanculo, Rahat Qureshi, Sana Sheikh, Zahra Hoodbhoy, Imran Ahmed, Amjad Hussain, Javed Memon, Farrukh Raza, Olalekan O. Adetoro, John Sotunsa, Sharla Drebit, Chirag Kariya, Mansun Lui, Diane Sawchuck, Ugochi V Ukah, Mai‐Lei Woo Kinshella, Shafik Dharamsi, Guy A. Dumont, Tabassum Firoz, Ana Pilar Betrán, Susheela Engelbrecht, Véronique Filippi, William A. Grobman, Marian Knight, Ana Langer, Simon Lewin, Gwyneth Lewis, Craig Mitton, Nadine Schuurman, Jim Thornton, France Donnay, Romano Byaruhanga, Brian A. Darlow, Eileen K. Hutton, Mario Merialdi, Lehana Thabane, Kelly Pickerill, Avinash Kavi, Chandrashekhar Karadiguddi, Sangamesh Rakaraddi, Amit Revankar,
Abstract Background Iron-deficiency anemia is a known risk factor for several adverse perinatal outcomes, but data on its impact on specific maternal morbidities is less robust. Further, information on associations between anemia in early pregnancy and subsequent outcomes are understudied. Methods The study population was derived from the Community Level Interventions for Pre-eclampsia (CLIP) trial in Karnataka State, India (NCT01911494). Included were women who were enrolled in either trial arm, ...
Tópico(s): Child Nutrition and Water Access
2022 - BioMed Central | BMC Pregnancy and Childbirth
Emilia Lombardi, Anthony J. Silvestre, Janine E. Janosky, Gregory L. Fisher, Charles R. Rinaldo,
... Diseases and Microbiology, University of PittsburghPittsburgh, PA Correspondence: Emilia Lombardi, Ph.D., Assistant Professor, Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, 3520 Fifth Avenue, Suite 400, Pittsburgh, PA 15213-3313, USA. Tel: +1 (412) 383-2233; Fax: +1 (412) 383-1513; E-mail: elombardi@stophiv.pitt.edu Search for other works by this author on: Oxford Academic PubMed Google Scholar Anthony J. Silvestre, Anthony J. Silvestre 1Department of Infectious Diseases and ...
Tópico(s): Adolescent Sexual and Reproductive Health
2008 - Oxford University Press | Nicotine & Tobacco Research
Sossio Cimmino, Edoardo D'Alma, Maria Laura Di Lorenzo, Emilia Di Pace, Clara Silvestre,
This article discusses the influence of two natural terpene resins (NTR), poly(α-pinene) (PαP A115) and poly(d-limonene) (PL C115), on morphology, miscibility, thermal, and dynamic-mechanical properties of their blends with isotactic polypropylene (iPP). The NTR have interesting physical and chemical properties, and they are approved for food contact application. From the results of differential scanning calorimetry and dynamic-mechanical thermal analysis it was deduced that both the resins were completely ...
Tópico(s): Polymer Nanocomposites and Properties
1999 - Wiley | Journal of Polymer Science Part B Polymer Physics
Clara Silvestre, Sossio Cimmino, Edoardo D'Alma, Maria Laura Di Lorenzo, Emilia Di Pace,
The influence of two natural terpene resins on the morphology, phase structure and isothermal crystallization process of iPP was investigated by optical (OM) and electron microscopy (SEM) and differential scanning calorimetry (DSC). It was found that in dependence on temperature, composition and chemical nature of the resin, one, two or three phases can be present. The isothermal spherulite growth rate and overall crystallization rate of the blends are depressed compared to plain iPP. This depression ...
Tópico(s): biodegradable polymer synthesis and properties
1999 - Elsevier BV | Polymer
Clara Silvestre, Sossio Cimmino, Emilia Di Pace, Maria Laura Di Lorenzo, M. Monaco,
Abstract The paper discusses the influence of an amorphous oligomer (namely hydrogenated oligocyclopentadiene — HOCP) on the morphology and the phase structure of its blends with several polyolefins as a function of composition and crystallization conditions. In particular the following polyolefins were studied: high-density polyethylene (HDPE), isotactic polypropylene (IPP), poly(l-butene) (PB-1), and poly(4-methyl pentene-1) (P4MP1). The blends under investigation are complex polymer systems. In fact, ...
Tópico(s): Polymer Nanocomposites and Properties
1996 - Taylor & Francis | Journal of Macromolecular Science Part B
Sossio Cimmino, Maria Laura Di Lorenzo, Emilia Di Pace, Clara Silvestre,
The article discusses the influence of the oligomeric resin, hydrogenated oligo(cyclopentadiene) (HOCP), on the morphology and properties of its blends with isotactic poly(1-butene) (PB-1). PB-1 and HOCP are found to be partially miscible in the melt state. Solidified PB-1/HOCP blends contain three phases: (1) a crystalline phase formed by PB-1 crystals; (2) an amorphous PB-1-rich phase; and (3) an amorphous HOCP-rich phase. The optical micrographs of the solidified blends show a morphology constituted ...
Tópico(s): biodegradable polymer synthesis and properties
1998 - Wiley | Journal of Applied Polymer Science
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre,
Abstract By using optical microscopy, small‐angle X‐ray scattering and differential scanning calorimetry, the melting behaviour and the structural parameters of poly(ethylene oxide)/poly(methyl methacrylate) (PEO/PMMA) blends are determined. The equation that relates the observed melting temperature, T m ′, to the lamellar thickness is used for the determination of the equilibrium melting temperature, T m . In the case of blends a small depression in the equilibrium melting point is observed. The depression ...
Tópico(s): biodegradable polymer synthesis and properties
1990 - Wiley | Die Makromolekulare Chemie
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre,
Tópico(s): Polymer Nanocomposites and Properties
1988 - Wiley | Die Makromolekulare Chemie Rapid Communications
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre,
The results of an investigation into the isothermal crystallization and thermal behaviour of syndiotactic polystyrene (sPS) are reported. The study was carried out using differential scanning calorimetry, optical microscopy and dilatometry. From the melt, sPS crystallizes according to a spherulite morphology. The spherulite growth rate and overall crystallization rate depend on crystallization temperature and sample preparation. During the crystallization process, segregation of impurities and non- ...
Tópico(s): Polymer Nanocomposites and Properties
1991 - Elsevier BV | Polymer
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre, David M. Rice, Frank E. Karasz,
The dependence of miscibility on blend composition and temperature for syndiotactic polystyrene/poly(vinyl methyl ether) (SPS/PVME) blends, was investigated by solid state n.m.r. spectroscopy and d.s.c. and compared with that of the blend containing atactic polystyrene (APS). The temperature dependence of 13C cross polarization/magic angle spinning intensities for the resonance of SPS/PVME blends indicates that these blends are phase separated, whereas for the APS/PVME blends, there is evidence of ...
Tópico(s): Material Properties and Processing
1993 - Elsevier BV | Polymer
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre,
The crystallization from the melt, the morphology and the miscibility of syndiotactic polystyrene/poly(vinyl methyl ether) (SPS/PVME) blends and syndiotactic polystyrene/poly(2,6-dimethyl-1,4-diphenylene oxide) (SPS/PPO) blends have been analysed by differential scanning calorimetry and optical microscopy. It was found that the kinetic parameters are strongly altered by the blending and by the crystallization conditions. In particular, the spherulite growth rate of SPS decreases if PPO is added, whereas ...
Tópico(s): Polymer Science and PVC
1993 - Elsevier BV | Polymer
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Clara Silvestre, Luis Cláudio Mendes, G. Bonfanti,
Abstract The influence of hydrogenated olio(cyclopentadiene) (HOCP) on tensile mechanical properties of its blends with high density polyethylene (HDPE) has been studied at 20, 80, and 100°C. The nominal stress‐strain curves performed at 20°C indicate an increase of the modulus and a conspicuous decrease of the ultimate properties increasing the HOCP content in the blend. Blends with HOCP content > 20%‐wt are found to be very fragile at 20°C. These behaviors have been related to the presence of the ...
Tópico(s): Natural Fiber Reinforced Composites
1995 - Wiley | Journal of Polymer Science Part B Polymer Physics
Clara Silvestre, Sossio Cimmino, Emilia Di Pace, M. Monaco,
Abstract The paper discusses the morphology, melting behavior, and process of crystallization of poly(4-methylpentene-1) (P4MP1) and its blends with an amorphous oligomer, hydrogenated oligocyclopent-adiene (HOCP). The study was performed by using optical and electron microscopy, differential scanning calorimetry and X-ray scattering. In all ranges of compositions and temperatures investigated, P4MP1 and HOCP components were not miscible. The HOCP formed segregated domains in the P4MP1 matrix. Depending ...
Tópico(s): biodegradable polymer synthesis and properties
1998 - Taylor & Francis | Journal of Macromolecular Science Part A
Alejandro Ibáñez, Uwe Fritz, Markus Auer, Albert Martı́nez Silvestre, Peter Praschag, Emilia Załugowicz, Dagmara Podkowa, Maciej Pabijan,
Abstract Despite the relevance of chemical communication in vertebrates, comparative examinations of macroevolutionary trends in chemical signaling systems are scarce. Many turtle and tortoise species are reliant on chemical signals to communicate in aquatic and terrestrial macrohabitats, and many of these species possess specialized integumentary organs, termed mental glands (MGs), involved in the production of chemosignals. We inferred the evolutionary history of MGs and tested the impact of macrohabitat ...
Tópico(s): Turtle Biology and Conservation
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
D.K Lenharo, Maria Emília Bodini Santiago, Simone Baldini Lucheis,
Com o objetivo de analisar a resposta sorológica à leptospirose, utilizando-se da técnica de Soroaglutinação Microscópica (SAM), no período de 2008 a 2009, foram avaliadas 72 amostras de soros de mamíferos silvestres pertencentes ao Parque Zoológico Municipal de Bauru. Destes, 60 (83,3%) foram reagentes aos seguintes sorovares: Pyrogenes (15,2%); Pomona (9,4%); Autumnalis (8,9%); Whitcombi (6,8%); Tarassovi (6,3%); Hardjo (5,7%); Butembo e Bratislava (4,7%); Wolffi (4,2%); Copenhageni (3,7%); Javanica, Hardjobovis ...
Tópico(s): Viral Infections and Vectors
2012 - Zeppelini Editorial | Arquivos do Instituto Biológico
Produção Nacional
Revisado por pares
Ana Raquel Mendes dos Santos, Luciano Machado Ferreira Tenório de Oliveira, José Cazuza de Farias Júnior, Priscilla Silva, Emília Silva, Clara Maria Silvestre Monteiro de Freitas,
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Tópico(s): Religion, Spirituality, and Psychology
2015 - Sociedade Brasileira de Atividade Física & Saúde | Revista Brasileira de Atividade Física & Saúde
Produção Nacional
Revisado por pares
Sossio Cimmino, Emilia Di Pace, E. Martuscelli, Luis Cláudio Mendes, Clara Silvestre,
Abstract The article discusses the influence of an oligomeric resin, hydrogenated oligo (cyclopentadiene) (HOCP), on the morphology and properties of its blends with high density polyethylene (HDPE). HDPE/HOCP blends after solidification contain three phases: the crystalline phase of HDPE and two amorphous phases, one rich in amorphous HDPE and the other in HOCP. DSC thermograms and the loss modulus behaviors show that the γ transition is influenced by HOCP molecules and, in addition to the α c transition ...
Tópico(s): Rheology and Fluid Dynamics Studies
1994 - Wiley | Journal of Polymer Science Part B Polymer Physics
Sossio Cimmino, Emilia Di Pace, Frank E. Karasz, E. Martuscelli, Clara Silvestre,
The phase structure and the dynamic-mechanical properties of isotropic films of isotactic polypropylene iPP)/hydrogenated oligocyclopentadiene (HOCP) blends are reported. It is found that the phase diagram presents both the lower critical solution temperature and the upper critical solution temperature. The dynamic-mechanical tests (performed at a frequency of 1 Hz and at a heating rate of 4°C min−1) show that the addition of HOCP > 20 wt% causes an increase of the storage modulus at low temperatures; ...
Tópico(s): Natural Fiber Reinforced Composites
1993 - Elsevier BV | Polymer
Marcos Rauch González, Emilia Catalán Martina, Guido Aguilera Bascur, Ivonne Valenzuela Vergara, Sandro Maldonado Osorio, Paula Palma,
es uno de los principales mecanismos de conservación de la diversidad biológica en Chile.Comunidades indígenas habitan en y en torno a áreas que componen el SNASPE, sustentándose en recursos naturales de diversos ecosistemas.En las últimas dos décadas CONAF se ha planteado el desafío de avanzar hacia una "gestión institucional con pertinencia cultural".Mediante el análisis de cuatro casos, se dará cuenta de los avances y brechas en términos de un trabajo intercultural en Áreas Silvestres Protegidas ...
Tópico(s): Water Resource Management and Quality
2018 - Austral University of Chile | Revista Austral de Ciencias Sociales
Laura A. Magee, Jeffrey N. Bone, Salwa Owasil, Joel Singer, Terry Lee, Mrutyunjaya Bellad, Shivaprasad S. Goudar, Alexander G. Logan, Salésio Macuácua, Ashalata Mallapur, Hannah L. Nathan, Rahat Qureshi, Esperança Sevene, Andrew Shennan, Anifa Valá, Marianne Vidler, Zulfiqar A Bhutta, Peter von Dadelszen, Eusébio Macete, Khátia Munguambe, Charfudin Sacoor, Helena Boene, Felizarda Amose, Rosa Pires, Zefanias Nhamirre, Marta Macamo, Rogério Chiaú, Analisa Matavele, Faustino Vilanculo, Ariel Nhancolo, Silvestre Cutana, Ernesto Mandlate, Cassimo Bique, Jeffrey N. Bone, Emília Gonçálves, Sónia Maculuve, Ana Ilda Biz, Dulce Mulungo, Orvalho Augusto, Paulo Filimone, Vivalde Nobela, Corsino Tchavana, Cláudio Nkumbula, Zahra Hoodbhoy, Farrukh Raza, Sana Sheikh, Javed Memon, Imran Ahmed, Amjad Hussain, Umesh Charantimath, Geetanjali Katageri, Avinash Kavi, Amit Revankar, Umesh Y Ramdurg, Shashidhar G Bannale, Vaibhav B Dhamanekar, Geetanjali I Mungarwadi, Narayan V Honnungar, Bhalachandra S. Kodkany, Anjali Joshi, Uday S Kudachi, Sphoorthi S Mastiholi, Chandrappa C Karadiguddi, Gudadayya S Kengapur, Namdev A Kamble, Keval S Chougala, Dustin Dunsmuir, Sharla Drebit, Chirag Kariya, Mai‐Lei Woo Kinshella, Tang Lee, Jing Li, Mansun Lui, Beth A. Payne, Diane Sawchuck, Sumedha Sharma, Domena K. Tu, Ugochi V Ukah, J. Mark Ansermino, Ana Pilar Betrán, Richard J. Derman, Shafik Dharamsi, France Donnay, Sharla Drebit, Guy A. Dumont, Susheela Engelbrecht, Veronique Fillipi, Tabassum Firoz, William A. Grobman, Marian Knight, Ana Langer, Simon Lewin, Gwyneth Lewis, Craig Mitton, Nadine Schuurman, Jim Thornton, Hubert Wong, Olalekan O. Adetoro, Khátia Munguambe, Beth A. Payne, Charfudin Sacoor, Sumedha Sharma, John Sotunsa, Romano Byaruhanga, Brian A. Darlow, Eileen K. Hutton, Mario Merialdi, Lehana Thabane,
[Figure: see text].
Tópico(s): Global Maternal and Child Health
2021 - Lippincott Williams & Wilkins | Hypertension
Rajesh Kumar, Samantha Milanesi, Martyna Szpakowska, Laura Dotta, Dario Di Silvestre, Anna Maria Trotta, Anna Maria Bello, Mauro Giacomelli, Manuela Benedito, Joana Azevedo, A. da S. Pereira, Emília Cortesão, Alessandro Vacchini, Alessandra Castagna, Marinella Pinelli, Daniele Moratto, Raffaella Bonecchi, Massimo Locati, Stefania Scala, Andy Chevigné, Elena Monica Borroni, Raffaele Badolato,
WHIM syndrome is an inherited immune disorder caused by an autosomal dominant heterozygous mutation in CXCR4. The disease is characterized by neutropenia/leukopenia (secondary to retention of mature neutrophils in bone marrow), recurrent bacterial infections, treatment-refractory warts, and hypogammaglobulinemia. All mutations reported in WHIM patients lead to the truncations in the C-terminal domain of CXCR4, R334X being the most frequent. This defect prevents receptor internalization and enhances ...
Tópico(s): interferon and immune responses
2023 - American Society for Clinical Investigation | JCI Insight
José María Bastida, Mónica del Rey, Marı́a Luisa Lozano, María Eugenia Sarasquete, Rocío Benito, M Elena Fontecha, Rosa Fisac, Luis J. Garcia‐Frade, C. Aguilar, María Paz Martínez, Emilia Pardal, Carmen Aguilera, Beatriz Pérez, Rúben J. Ramos, M. R. Cardesa, Jose Manuel Martin-Antorán, L. A. Silvestre, María José Cebeira, Nuria Bermejo, Susana Riesco, M. Carmen Mendoza, Ramón García‐Sánz, Marcos González, Jesús María Hernández‐Rivas, José Ramón González‐Porras,
Molecular testing of Inherited bleeding coagulation disorders (IBCDs) not only offers confirmation of diagnosis but also aids in genetic counselling, prenatal diagnosis and in certain cases genotype-phenotype correlations are important for predicting the clinical course of the disease and to allow tailor-made follow-up of individuals. Until recently, genotyping has been mainly performed by Sanger sequencing, a technique known to be time consuming and expensive. Currently, next-generation sequencing ( ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2016 - Wiley | Haemophilia