Produção Nacional
Revisado por pares
Marcos Emerson Pinheiro Junqueira, Lidiane Zito Grund, Noemia Mie Orii, Tânia Cristina Saraiva, Carlos Alberto de Magalhães Lopes, Carla Lima, Mônica Lopes‐Ferreira,
Cathorops spixii is one of the most abundant venomous fish of the southeastern coast of the State of São Paulo, and consequently causes a great part of the accidents seen there. The accidents affect mainly fishermen, swimmers and tourists and are characterized by punctiform or wide wounds, erythema, edema, pain, sudoresis, indisposition, fever, nausea, vomiting and secondary infection. The objective of this work was to characterize the inflammatory response induced in mice by both venoms (mucus and ...
Tópico(s): Healthcare and Venom Research
2007 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Julio Acosta‐Navarro, Laís Ferreira Dias, Luiza Antoniazzi, Emerson Pinheiro Ferreira, Marcos Vinnícius Pires Fernandes de Oliveira, Flávia Andréia Marin, José Valter Costa Oliveira, Andressa Candida da Silva, Isabella Louise Silva, Fabiane de Oliveira Freitas, Paulo Rogério Soares,
To evaluate the influence of dietary patterns on the incidence and evolution of COVID-19. We hypothesised that a plant-based diet or a vegetarian diet compared with an omnivorous diet might be associated with a lower incidence of COVID-19 infection and severity in those infected.
Tópico(s): Food Waste Reduction and Sustainability
2024 - BMJ | BMJ Nutrition Prevention & Health
Produção Nacional
Nikolas Rose, Emerson Rodrigo Pinheiro Martins,
Todos os dias, nossos meios de comunicação noticiam algum maravilhoso e inovador avanço na biomedicina -novas tecnologias de reprodução que dão esperança aos inférteis e permitem aos pais "moldarem" seus filhos, novos tratamentos com célulastronco para lesões na coluna vertebral e para Alzheimer, novas maneiras de examinar nossos genomas à procura de fragilidades no organismo, remédios que irão não apenas aliviar nossa depressão, mas também nos deixar mais felizes e inteligentes, drogas que podem ...
Tópico(s): Pharmaceutical industry and healthcare
2010 - Associação Brasileira de Psicologia Social | Psicologia & Sociedade
Produção Nacional
Revisado por pares
Tércio de F. Paulo, Maria A. S. da Silva, Solange de Oliveira Pinheiro, Emerson Meyer, Lucidalva S. Pinheiro, J. A. K. Freire, Auro Atsushi Tanaka, Pedro de Lima‐Neto, Ícaro de Sousa Moreira, Izaura C.N. Diógenes,
5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol (Hpyt) spontaneously adsorbs on gold forming SAMs (self-assembled monolayers) that, based on STM (Scanning Tunneling Microscopy) and electrochemical data, contain pinholes through which [Fe(CN)6]4- and [Ru(NH3)6]3+ probe molecules access the underlying gold electrode. For the former molecule, the dependence of the faradaic current on the electrolyte solution pH value allowed the evaluation of the surface pKa as 4.2. The thermodynamic parameters DHads and DGads ...
Tópico(s): Conducting polymers and applications
2008 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society
Produção Nacional
Revisado por pares
Mavis Tsai, Emerson Hardebeck, Fabiana Pinheiro Ramos, Hannah Turlove, Kaisa Nordal‐Jonsson, Akoly Vongdala, Wen Zhang, Robert J. Kohlenberg,
A second pandemic of mental health problems due to COVID-19 is predicted, suggesting a demand for interventions to mitigate its impacts. This study evaluated the effectiveness of an online psychological intervention based on the Awareness, Courage, and Love (ACL) model from Functional Analytic Psychotherapy to promote closeness between couples during the pandemic.Thirty-one couples were randomised into either the intervention or control group for a 2-hour online group session. The intervention was ...
Tópico(s): Resilience and Mental Health
2020 - Wiley | Applied Psychology Health and Well-Being
Produção Nacional
Revisado por pares
Tamyris T. da Cunha, Vitor M. M. Barbosa, Willian X. C. Oliveira, Carlos B. Pinheiro, Emerson F. Pedroso, Wallace C. Nunes, Cynthia L. M. Pereira,
A series of lanthanide(III) oxamate complexes of formula Na[Eu(4-HOpa)4(H2O)]∙2H2O (1), Na[Gd(4-HOpa)4(H2O)]∙2H2O (2), Na[Dy(4-HOpa)4(H2O)]∙2H2O (3), and Na[Ho(4-HOpa)4(H2O)]∙2H2O (4) (4-HOpa = N-4-hydroxyphenyloxamate) were synthesized and characterized. The crystal structures of complexes 1–4, as well as the oxamate ligand in the ethyl ester acid form (Et[4-HOpa]), were elucidated by single crystal X-ray diffraction. 1–4 are isostructural, and they crystallize in the P21/n space group of the monoclinic ...
Tópico(s): Electron Spin Resonance Studies
2019 - Elsevier BV | Polyhedron
Produção Nacional
Revisado por pares
Ellen Games, Marina Guerreiro, Fernanda Paula Roncon Santana, Nathália M. Pinheiro, Emerson de Oliveira, Fernanda Degobbi Tenório Quirino dos Santos Lopes, Clarice Rosa Olivo, Iolanda de Fátima Lopes Calvo Tibério, Mílton A. Martins, João Henrique G. Lago, Carla M. Prado,
Background: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction and inflammation. Natural products, such as monoterpenes, displayed anti-inflammatory and anti-oxidant activities and can be used as a source of new compounds to COPD treatment. Our aim was to evaluate, in an elastase-induced pulmonary emphysema in mice, the effects of and underlying mechanisms of three related natural monoterpenes (p-cymene, carvacrol and thymol) isolated from essential oil ...
Tópico(s): Respiratory and Cough-Related Research
2016 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Vinícius Menezes Tunholi-Alves, Victor Menezes Tunholi, Juberlan Silva Garcia, Éster Maria Mota, Rosane Nora Castro, Emerson Guedes Pontes, Jairo Pinheiro,
Tópico(s): Medical and Biological Ozone Research
2018 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Daniele Cristina Barcelos, Emerson Monteiro Vieira, Marcell Soares Pinheiro, Guilherme Braga Ferreira,
Abstract Worldwide, nature-based tourism is becoming more popular and important economically. However, there is still debate regarding its impact on wildlife in protected areas. We conducted a quasi-experimental study to investigate the effects of tourism on the mammal community of Cavernas do Peruaçu National Park, a priority area for conservation in Brazil. We used camera traps to survey tourist and non-tourist trails during 2011–2017, encompassing periods before and after tourism started in the ...
Tópico(s): Wildlife-Road Interactions and Conservation
2022 - Cambridge University Press | Oryx
Produção Nacional
Revisado por pares
Igor Duarte Rodrigues, Emerson Carvalho, Caio Pinheiro Santana, Guilherme Sousa Bastos,
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized primarily by social impairments that manifest in different severity levels. In recent years, many studies have explored the use of machine learning (ML) and resting-state functional magnetic resonance images (rs-fMRI) to investigate the disorder. These approaches evaluate brain oxygen levels to indirectly measure brain activity and compare typical developmental subjects with ASD ones. However, none of these works have tried ...
Tópico(s): Neuroscience and Neural Engineering
2022 - Multidisciplinary Digital Publishing Institute | Algorithms
Produção Nacional
Revisado por pares
Célia Mantovani, Paulo Louzada‐Júnior, Emerson Arcoverde Nunes, Felipe Pinheiro de Figueiredo, Glício Rebouças Oliveira, Cristina Marta Del‐Ben,
Abstract Aims: This report discusses the use of antinuclear antibody (ANA) detection as a screening test for neuropsychiatry systemic lupus erythematosus (NPSLE) in patients presenting a first‐episode psychosis. Methods: We reviewed the medical records of 85 patients admitted to an emergency service due to first‐episode psychosis, during a 1‐year period, for whom ANA detection was performed through an IFI HEp2 cell assay. ANA‐positive patients were subsequently evaluated for autoantibodies and neuroimaging ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2012 - Wiley | Early Intervention in Psychiatry
Produção Nacional
Revisado por pares
Caio Pinheiro Santana, Emerson Carvalho, Igor Duarte Rodrigues, Guilherme Sousa Bastos, Adler Diniz de Souza, Lucelmo Lacerda de Brito,
Autism Spectrum Disorder (ASD) diagnosis is still based on behavioral criteria through a lengthy and time-consuming process. Much effort is being made to identify brain imaging biomarkers and develop tools that could facilitate its diagnosis. In particular, using Machine Learning classifiers based on resting-state fMRI (rs-fMRI) data is promising, but there is an ongoing need for further research on their accuracy and reliability. Therefore, we conducted a systematic review and meta-analysis to summarize ...
Tópico(s): Neural dynamics and brain function
2022 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Ricardo de Oliveira Barbosa Bitencourt, Jacenir Reis dos Santos Mallet, Emily Mesquita, Patrícia Silva Gôlo, Jéssica Fiorotti, Vânia Rita Elias Pinheiro Bittencourt, Emerson Guedes Pontes, Isabele da Costa Angelo,
Blastospores or conidia (formulated or not) of entomopathogenic fungi were assessed against Aedes aegypti larvae. Larvae (L2) were exposed to 105, 106, 107, and 108 propagules mL−1 water suspension. Mineral oil at 0.1%, 0.5%, or 1.0% (v/v) was employed to observe the effect on larval survival. The 0.1% mineral oil did not affect larval survival. Accordingly, 107 propagules mL−1 and 0.1% mineral oil were used to prepare all fungal emulsions. The fungal suspension or formulation was prepared as follows: ...
Tópico(s): Insect Resistance and Genetics
2020 - Elsevier BV | Acta Tropica
Produção Nacional
Revisado por pares
Renyer A. Costa, Earle Silva A., Jaqueline de Araújo Bezerra, Josiana Moreira Mar, Émerson Silva Lima, Maria Lúcia B. Pinheiro, Diego V. C. Mendonça, Guilherme Braule P. Lopes, Adjane Dalvana Sampaio Branches, Kélson Mota Teixeira de Oliveira,
4-Nerolidylcatechol (4NRC), a secondary metabolite described as a potent antioxidant that presents anti-inflammatory, antimalarial, analgesic, and cytotoxic properties, has been receiving prominence in the catechol class. In this work, a theoretical DFT study of the vibrational, structural, and quantum properties of 4-nerolidylcatechol (4NRC) using the B3LYP/6-311G (2d,p) level is presented. The theoretical molecular geometry data were compared with the X-ray data of a similar molecule in the associated ...
Tópico(s): Nonlinear Optical Materials Research
2019 - Hindawi Publishing Corporation | Journal of Chemistry
Produção Nacional
Revisado por pares
Isabele da Costa Angelo, Patrícia Silva Gôlo, Wendell Marcelo de Souza Perinotto, Mariana Guedes Camargo, Simone Quinelato, Fillipe Araújo de Sá, Emerson Guedes Pontes, Vânia Rita Elias Pinheiro Bittencourt,
Tópico(s): Physiological and biochemical adaptations
2012 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Tamyris T. da Cunha, Willian X. C. Oliveira, Carlos B. Pinheiro, Emerson F. Pedroso, Wallace C. Nunes, Cynthia L. M. Pereira,
Three new coordination compounds of formula (edap)2[Cu(opba)]2·4H2O (1), (edap)[{Na2(H2O)4}{Cu2(opba)2}]·2H2O (2), and (edap)[{K2(H2O)2}{Cu2(opba)2}]·3H2O (3) (edap = 1,1′-ethylenebis(4-aminopyridinium) and opba = 1,2-phenylenebis(oxamate)) were synthesized through the metathesis reaction involving A2[Cu(opba)] (A = Li+, Na+, and K+) and (edap)Cl2·2H2O. Crystal structures of 1–3 and edap(IO3)2·4H2O compound were elucidated by single crystal X-ray diffraction. Compounds 1–3 are built up from dinuclear copper(II) ...
Tópico(s): Lanthanide and Transition Metal Complexes
2016 - American Chemical Society | Crystal Growth & Design
Produção Nacional
Revisado por pares
Emerson Carvalho, Caio Pinheiro Santana, Igor Duarte Rodrigues, Lucelmo Lacerda, Guilherme Sousa Bastos,
Genetic factors have been pointed out as the primary root associated with the risk of autism. Recent works indicate that approximately 80% of autistic people have inherited the condition from their parents. However, there are no estimates that indicate the likelihood of an autistic parent having an autistic child. Using Hidden Markov Models, together with the data of autism heritability, we developed a model to investigate the likelihood of autistic parents generating autistic children. Hidden Markov ...
Tópico(s): Genomic variations and chromosomal abnormalities
2020 - Institute of Electrical and Electronics Engineers | IEEE Access
Produção Nacional
Revisado por pares
Nélida Simone Martinez Landeira Miqueleto, Sheila Canevese Rahal, Felipe Stéfan Agostinho, Emerson Gonçalves Martins de Siqueira, Fábio André Pinheiro de Araújo, A. O. El‐Warrak,
This study investigated kinematic patterns in clinically normal German Shepherd dogs (GSDs) compared to those with hip dysplasia and with no clinical signs of lameness. Two groups of GSDs, including 10 clinically healthy dogs (G1) and 10 with hip dysplasia (G2), were trotted on a treadmill at a constant speed. Kinematic data were collected by a 3-camera system and analysed by a motion-analysis program. Flexion and extension joint angles and angular velocities were determined for the shoulder, elbow, ...
Tópico(s): Hip disorders and treatments
2012 - Elsevier BV | The Veterinary Journal
Produção Nacional
Revisado por pares
Juliana Vanessa Colombo Martins Perles, Gleison Daion Piovezana Bossolani, Isabela Zignani, Sara Raquel Garcia de Souza, Flávia Cristina Vieira Frez, Carina Guimarães de Souza Melo, Emerson Barili, Fernando Pinheiro de Souza Neto, Flávia Alessandra Guarnier, Alessandra Lourenço Cecchini Armani, Rúbens Cecchini, Jacqueline Nelisis Zanoni,
Considering the antioxidant, neuroprotective, inflammatory and nitric oxide modulatory actions of quercetin, the aim of this study was to test the effect of quercetin administration in drinking water (40 mg/day/rat) on neuronal nitric oxide synthase (nNOS), vasoactive intestinal peptide (VIP), overall population of myenteric neurons (HuC/D) and nitric oxide (NO) levels in the jejunal samples from diabetic rats. Male Wistar rats were distributed into four groups (8 rats per group): euglycemic (E), euglycemic ...
Tópico(s): Gastrointestinal motility and disorders
2020 - Elsevier BV | Autonomic Neuroscience
Produção Nacional
Emerson Tavares de Sousa, MA Pinheiro, PP Maciel, Marcelo Augusto Oliveira de Sales,
The use of cone-beam computed tomography images (CBCT) providing a better assessment of bone injuries, although the sensibility of lesions measurement might be improved by the use of enhancement filters. Objective: This study aimed to analyze the influence of enhancement filters in apical bone loss measurement.Eighteen CBCT cases randomly selected of apical bone loss were evaluated. The analyses were carried out following the evaluation in axial, coronal and sagittal protocols, using enhancement ...
Tópico(s): Dental Implant Techniques and Outcomes
2017 - Medicina Oral S.L. | Journal of Clinical and Experimental Dentistry
Produção Nacional
Revisado por pares
Leonardo de Sousa Fortes, Gustavo César Vasconcelos, Bruna Costa, Pedro Pinheiro Paes, Émerson Franchini,
The objective of the present study was to analyze the effect of 10% body mass reduction on simulated taekwondo match performance. Thirty-one male taekwondo athletes were randomly distributed in two groups: weight loss group (n= 15) – athletes in this group reduced 5% body mass per week during two successive weeks, totaling 10% body mass reduction; control group (n= 16) – athletes in this group kept their body mass constant during the 2-week period. Twenty-four hours before and after this period, athletes ...
Tópico(s): Sport Psychology and Performance
2017 - | Journal of Exercise Rehabilitation
Produção Nacional
Revisado por pares
Ricardo de Oliveira Barbosa Bitencourt, Fernanda de Souza Faria, Paula Marchesini, Jacenir Reis dos Santos Mallet, Mariana Guedes Camargo, Vânia Rita Elias Pinheiro Bittencourt, Emerson Guedes Pontes, Débora Baptista Pereira, Douglas Siqueira de Almeida Chaves, Isabele da Costa Angelo,
Aedes aegypti transmits arbovirus, which is a public health concern. Certain filamentous fungi have the potential to control the disease. Here, the effects of Metarhizium anisopliae s.l. CG 153, Beauveria bassiana s.l. CG 206 and Schinus molle L. were investigated against Aedes aegypti larvae. In addition, the effect of essential oil on fungal development was analyzed. Fungal germination was assessed after combination with essential oil at 0.0025 %, 0.0075 %, 0.005 %, or 0.01 %; all of the oil concentrations ...
Tópico(s): Insect Utilization and Effects
2022 - Elsevier BV | Journal of Invertebrate Pathology
Produção Nacional
Revisado por pares
Tatiana R. G. Simões, Walace D. do Pim, Karina C. Metz, Marcos A. Ribeiro, Daniel C. A. Valente, Thiago M. Cardozo, Carlos B. Pinheiro, Emerson F. Pedroso, Bruno A. C. Horta, Cynthia L. M. Pereira, G.P. de Souza, Humberto O. Stumpf,
Dicopper( ii ) complexes were prepared as promising platforms for the design of polynuclear systems providing an avenue toward new molecule-based materials.
Tópico(s): Metal complexes synthesis and properties
2020 - Royal Society of Chemistry | New Journal of Chemistry
Produção Nacional
Revisado por pares
Vanessa M. Freitas, Jônatas Bussador do Amaral, Thaiomara A. Silva, Emerson de Souza Santos, Flávia Rotea Mangone, João de Jesus Viana Pinheiro, Ruy Gastaldoni Jaeger, María Aparecida Nagai, Gláucia Maria Machado‐Santelli,
ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motifs) is a member of the ADAMTS family of metalloproteases. Here, we investigated mRNA and protein levels of ADAMTS-1 in normal and neoplastic tissues using qPCR, immunohistochemistry and immunoblot analyses, and we addressed the role of ADAMTS-1 in regulating migration, invasion and invadopodia formation in breast tumor cell lines. In a series of primary breast tumors, we observed variable levels of ADAMTS-1 mRNA expression but lower ...
Tópico(s): Protease and Inhibitor Mechanisms
2013 - BioMed Central | Molecular Cancer
Produção Nacional
Revisado por pares
Alcides J. M. da Silva, Antonio L. Coelho, Alessandro B. C. Simas, Raphael A.M. Moraes, Diogo A. Pinheiro, Fabrício Freitas Fernandes, Emerson Z. Arruda, Paulo R. R. Costa, Paulo A. Melo,
Edunol (3), a pterocarpan isolated from Harpalyce brasiliana, a plant used in the northeast of Brazil against snakebites, was obtained by synthesis and showed antimyotoxic, antiproteolytic and PLA2 inhibitor properties. These proprieties could be improved through the synthesis of a bioisoster (5), where the prenyl group was replaced by the benzyl group.
Tópico(s): Synthesis and bioactivity of alkaloids
2003 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Produção Nacional
Revisado por pares
Vinícius Menezes Tunholi-Alves, Victor Menezes Tunholi, Patrícia Silva Gôlo, Mariana Gomes Lima, Juberlan Silva Garcia, Arnaldo Maldonado, Emerson Guedes Pontes, Vânia Rita Elias Pinheiro Bittencourt, Jairo Pinheiro,
Tópico(s): Medical and Biological Ozone Research
2013 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Basílio Smuczek, Emerson de Souza Santos, Adriane Sousa de Siqueira, João de Jesus Viana Pinheiro, Vanessa M. Freitas, Ruy Gastaldoni Jaeger,
Breast cancer is an important public health problem, and its progression may be related to the extracellular matrix (ECM), which acts as a structural scaffold and instruction source for neoplastic cells. Laminins are ECM proteins regulating tumor biology. The laminin-derived peptide C16 regulates different properties of tumor cells. Here we analyzed C16-induced differential gene expression in MDA-MB-231 breast cancer cells. MCF-10A normal-like breast cells served as control. Among different cancer- ...
Tópico(s): Glycosylation and Glycoproteins Research
2017 - Elsevier BV | Experimental Cell Research
Produção Nacional
Revisado por pares
Emerson de Oliveira, Rodrigo Aquino Castro, Cláudia Cristina Takano, Leonardo Robson Pinheiro Sobreira Bezerra, Marair Grácio Ferreira Sartori, Geraldo R. de Lima, Edmund Chada Baracat, Manoel Joâo Batista Castello Girão,
The objective was to evaluate the cross-sectional area (CSA) and the Doppler velocimetric parameters of the levator ani muscle vessels in premenopausal women with and without urinary stress incontinence.Sixty-three premenopausal women constituted three groups: GI (nulliparous), GII (continent multiparous), and GIII (incontinent multiparous). The patients had undergone transperineal ultrasound in which the CSA was measured and Doppler velocimetry was performed. The examination was repeated by a second ...
Tópico(s): Anorectal Disease Treatments and Outcomes
2006 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology
Produção Nacional
Revisado por pares
Emerson Feio Pinheiro, Patrick Bruno Cardoso, Waldo Lucas Luz, Nadyme Assad, Mateus Santos-Silva, Luana Ketlen Reis Leão, Suellen Alessandra Soares de Moraes, Adelaide da Conceição Fonseca Passos, Evander de Jesus Oliveira Batista, Karen Renata Herculano Matos Oliveira, Amauri Gouvêia, Anderson Manoel Herculano,
Background: Aggression is a set of complex behaviors commonly described in different neurological disorders, such as schizophrenia, autistim spectrum disorder, and anxiety. Previous studies have described that some changes in the redox status of the brain are closely associated with aggressive behavior in different species. In addition, the endocannabinoid system acts as a neuromodulator of the central nervous system, however, its participation in aggressive behavior needs to be elucidated. Danio ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2022 - Mary Ann Liebert, Inc. | Cannabis and Cannabinoid Research
Produção Nacional
Revisado por pares
Walace D. do Pim, Ingrid F. Silva, Eufrânio N. da Silva Júnior, Humberto O. Stumpf, Willian X. C. Oliveira, Emerson F. Pedroso, Carlos B. Pinheiro, Yves Journaux, Felipe Fantuzzi, Ivo Krummenacher, Holger Braunschweig, Bernd Engels, Joan Cano, Miguel Julve, Cynthia L. M. Pereira,
An unexpected heterobimetallic ring {CoII6CuII6} was synthesised by slow diffusion in water under ambient conditions and its dc magnetic properties were analysed through an effective Hamiltonian in the light of DFT type calculations.
Tópico(s): Lanthanide and Transition Metal Complexes
2021 - Royal Society of Chemistry | Dalton Transactions