
Lara Vargas Becker, Cíntia Saydelles da Rosa, Viviane do Carmo Gonçalves Souza, Margarete Dulce Bagatini, Émerson André Casali, Cláudio A.M. Leal, João Carlos N. da Silva, Maria Beatriz Moretto, Francielle de Vargas Pinheiro, Vera Maria Morsch, Maria Rosa Chitolina Schetinger, Daniela Bitencourt Rosa Leal,
To investigate whether there are changes in the activity of the enzymes NTPDase, 5'-nucleotidase, E-NPP and ADA in platelets from patients with rheumatoid arthritis (RA).Thirty-five RA patients diagnosed with RA through American College of Rheumatology criteria, as well as 35 healthy patients were selected. NTPDase, 5'-nucleotidase, E-NPP and ADA activities were verified in platelets isolated from these patients.The results demonstrate that an increase in NTPDase (approximately 100%), 5'-nucleotidase ( ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2010 - Elsevier BV | Clinical Biochemistry

Jorge Alberto Martins, Fábio Luiz Teixeira Gonçalves, Carlos A. Morales, Gilberto Fisch, Francisco Geraldo M Pinheiro, João Bosco Verçosa Leal, Carlos Jacinto de Oliveira, Emerson Mariano da Silva, José Carlos Parente de Oliveira, Alexandre Araújo Costa, Maria Assunção Faus da Silva Dias,
Tópico(s): Atmospheric Ozone and Climate
2009 - Springer Science+Business Media | Meteorology and Atmospheric Physics

Emerson Rogério Costa Santiago, Alcides da Silva Diniz, Juliana Souza Oliveira, Vanessa Sá Leal, Maria Izabel Siqueira de Andrade, Pedro Israel Cabral de Lira,
Background: Systemic arterial hypertension is a substantial public health problem responsible for millions of deaths per year worldwide. However, little is known about the epidemiology of this disease in areas distant from large urban centers in Brazil. Such information is necessary to plan health promotion strategies. Objective: To estimate the prevalence of hypertension and determine its associated factors in adults residing in the semi-arid region of the state of Pernambuco, Northeastern Brazil. ...
Tópico(s): Nutritional Studies and Diet
2019 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Thaís Gleice Martins Braga, Suyene Rocha Pinto, Sara Rhaissa Rezende dos Reis, Filipe Leal Portilho, Aline Oliveira da Silva de Barros, Emerson Soares Bernardes, Sofia Nascimento dos Santos, Luciana Magalhães Rebêlo Alencar, Eduardo Ricci‐Júnior, Ralph Santos‐Oliveira,
Tópico(s): Neuroblastoma Research and Treatments
2019 - Springer Science+Business Media | Pharmaceutical Research

Maria de Lourdes da Silva Rosa, Herbet Conceição, Felix Oberli, Martin Meier, Hervé Martin, Moacir José Buenano Macambira, EMERSON BARRETO DOS SANTOS, MÁRCIO MATTOS PAIM, GERALDO AUGUSTO DA SILVA LEAHY, Luíz Rogério Bastos Leal,
The Guanambi batholith (GB) is located in south-western Bahia, Brazil, where it forms part of the Urandi-Paratinga mobile belt. The batholith extends over an area of almost 6,000 km 2 and is mainly composed of syenites and monzonites, with subordinate granites, mafic syenites and lamprophyric dykes. Two main units can be recognized: the multiple intrusions, being divided into four regions (Paratinga, Laguna, Igaporã and Guanambi) and the so-called late-intrusions forming the Cara Suja, Ceraíma and ...
Tópico(s): earthquake and tectonic studies
2000 - Sociedade Brasileira de Geologia | Revista Brasileira de Geociências

Maria de Lourdes da Silva Rosa, Herbet Conceição, Felix Oberli, Martin Meier, Hervé Martin, Moacir José Buenano Macambira, Emerson Barreto dos Santos, M. M. Paim, Geraldo Augusto da Silva Leahy, Luíz Rogério Bastos Leal,
The Guanambi batholith (GB) is located in south-western Bahia, Brazil, where it forms part of the Urandi-Paratinga mobile belt. The batholith extends over an area of almost 6,000 km 2 and is mainly composed of syenites and monzonites, with subordinate granites, mafic syenites and lamprophyric dykes. Two main units can be recognized: the multiple intrusions, being divided into four regions (Paratinga, Laguna, Igapora and Guanambi) and the so-called late-intrusions forming the Cara Suja, Cerafma and ...
Tópico(s): earthquake and tectonic studies
2000 - Sociedade Brasileira de Geologia | Brazilian Journal of Geology

Maria Izabel Siqueira de Andrade, Juliana Souza Oliveira, Vanessa Sá Leal, Niedja Maria da Silva Lima, Phelipe Bibiano Bezerra, Emerson Rogério Costa Santiago, Pedro Israel Cabral de Lira,
To identify the prevalence of insulin resistance in adolescents and its associations with metabolic factors and food intake.Cross-sectional study conducted with a stratified, complex, school-based sample. The subjects were adolescents (n=1,081) who participated in the Study of Cardiovascular Risk in Adolescents in the city of Recife (Pernambuco, Brazil). We analyzed demographic, socioeconomic, behavioral, anthropometric, biochemical, and dietary variables. Insulin resistance was defined as HOMA-IR> ...
Tópico(s): Health and Lifestyle Studies
2020 - Elsevier BV | Revista Paulista de Pediatria

Aline Castilho Rodrigues, Elen Leal da Silva, Sandro Fonseca Quirino, Andrés Cuña, Jossano Saldanha Marcuzzo, Jorge Tadao Matsushima, Emerson Sarmento Gonçalves, Maurício Ribeiro Baldan,
The main challenge for the development of a high efficiency supercapacitor is the electrode material. Developing electrode materials with high specific electrical capacitance and low electrical resistance enables an increase in the energy accumulated in the device. In addition, it is expected that the electrode material presents a simple procedure for preparation having low production cost and being environmentally friendly. This work is based on the deposition of silver nanoparticles on activated ...
Tópico(s): Conducting polymers and applications
2018 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research

Lívia G. Castilhos, João Felipe Peres Rezer, Jader B. Ruchel, Maria Luiza Thorstenberg, Jeandre Augusto dos Santos Jaques, Josiane Bizzi Schlemmer, Pedro H. Doleski, Mateus F. Rossato, Mariane A. da Silva, Emerson André Casalli, Ritiel Corrêa da Cruz, Juliano Ferreira, Margareth Linde Athayde, Jamile F. Gonçalves, Daniela Bitencourt Rosa Leal,
Considering that adjuvant arthritis is an experimental model of arthritis widely used for preclinical testing of numerous anti-arthritic agents, which were taken by a large number of patients worldwide, it is of great interest to investigate the therapeutic action of compounds with anti-inflammatory properties, such as Uncaria tomentosa extract. Moreover, there are no studies demonstrating the effect of U. tomentosa on the metabolism of adenine nucleotides published so far. Thus, the purpose of ...
Tópico(s): Alkaloids: synthesis and pharmacology
2015 - BioMed Central | BMC Complementary and Alternative Medicine

Aline Castilho Rodrigues, E. Leal da Silva, Ana Paula Silva de Oliveira, Jorge Tadao Matsushima, Andrés Cuña, Jossano Saldanha Marcuzzo, Emerson Sarmento Gonçalves, Maurício Ribeiro Baldan,
Supercapacitors have received great attention in science and technology, due to its important qualities as the high cycle life, high power density, and variety of applications. The main challenge for the development of better devices is the electrode material. Developing electrode materials with high specific electrical capacitance and low electrical resistance enables an increase of energy accumulated in the supercapacitor. In addition, it is expected that the electrode material presents a simple ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2019 - Elsevier BV | Materials Today Communications

Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Lívia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valéria Nóbrega, Daniel de Araújo Batista, Priscila Leal e Leite, Eduardo Saad, Jadher Pércio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada, Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Lívia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valéria Nóbrega, Daniel de Araújo Batista, Priscila Leal e Leite, Eduardo Saad, Jadher Pércio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada,
Objective: to confirm Zika virus circulation and discard other etiological agents in an outbreak occurred in the states of Rio Grande do Norte, Maranhão and Paraíba, in May, 2015.Methods: this is a case series descriptive study with residents in Natal-RN, Barra do Corda-MA, São Luis-MA and João Pessoa-PB, with 20 cases in each state, presenting rash, absent or mild fever and one of the following signs/symptoms: conjunctival hyperemia, arthralgia or limb edema; RT-PCR/isolation tests for Zika, enterovirus ...
Tópico(s): Virology and Viral Diseases
2016 - MINISTÉRIO DA SAÚDE | Epidemiologia e Serviços de Saúde
Daniella Cristine Fialho Lopes, L. M. Geraldi, Wendel de Oliveira Afonso, C.B.D. Ornellas, MSc Robson Leal da Silva, Flávia Milagres Campos, Emerson Silami‐Garcia, M. P. C. Silvestre,
Tópico(s): Diet, Metabolism, and Disease
2009 - | American Journal of Food Technology

Lara Vargas Becker, Renata da Silva Pereira Saccol, Vera Maria Morsch, Daniela Bitencourt Rosa Leal, Émerson André Casali, Nina Gabriela Müller Lopes, Valesca Veiga Cardoso, Maria Rosa Chitolina Schetinger,
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease, where there is irreversible breakdown of immunological self-tolerance. Extracellular adenosine triphosphate (ATP) and adenosine are signaling molecules that play an important part in the immune response. During inflammation and the immune response, a group of enzymes control these molecules, including ectonucleoside triphosphate diphosphohydrolase (E-NTPDase), E-5'-nucleotidase, and ecto-adenosine deaminase (E-ADA). We determined ...
Tópico(s): Electrolyte and hormonal disorders
2018 - Elsevier BV | Clinica Chimica Acta

Talita Adelino, Marta Giovanetti, Vagner Fonseca, Joilson Xavier, Álvaro Salgado, Valdinete Alves do Nascimento, Luiz Henrique Ferraz Demarchi, Marluce Aparecida Assunção Oliveira, Vinícius Lemes da Silva, Arabela Leal e Silva de Mello, Gabriel Muricy Cunha, Roselene Hans Santos, Elaine Cristina de Oliveira, Jorge Antônio Chamon Júnior, Felipe Campos de Melo Iani, Ana María Bispo de Filippis, André Luiz de Abreu, Ronaldo de Jesus, Carlos F. Campelo de Albuquerque, Jairo Méndez‐Rico, Rodrigo Fabiano do Carmo Said, Joscélio Aguiar Silva, Noely Fabiana Oliveira de Moura, Priscila Leal e Leite, Lívia Carla Vinhal Frutuoso, Simone Kashima, Alexander A. Martínez, Fernanda Khouri Barreto, Cynthia Vázquez, Rivaldo Venâncio da Cunha, Emerson Luiz Lima Araújo, Stephane Tosta, Allison Fabri, Flávia Löwen Levy Chalhoub, Poliana da Silva Lemos, Fernanda de Bruycker‐Nogueira, Gislene Garcia de Castro Lichs, Marina Castilhos Souza Umaki Zardin, Fátima Cardozo, Crhistinne Cavalheiro Maymone Gonçalves, Zoraida del Carmen Fernandez Grillo, Svetoslav Nanev Slavov, Luiz Augusto Pereira, Ana Flávia Mendonça, Felicidade Mota Pereira, Jurandy Júnior Ferraz de Magalhães, Agenor de Castro Moreira dos Santos Júnior, Maricélia Maia de Lima, Rita Maria Ribeiro Nogueira, Aristóteles Goés‐Neto, Vasco Azevedo, Dario Brock Ramalho, Wanderson Kleber de Oliveira, Eduardo Marques Macário, Arnaldo Correia de Medeiros, Victor Pimentel, Erenilde Marques de Cerqueira, Tiago Gräf, Walter Massa Ramalho, Wildo Navegantes, Renato Barbosa Reis, Clara Guerra-Duarte, Maira Alves Pereira, Paulo Eduardo de Souza da Silva, Raoni Almeida de Souza, Alex Pauvolid‐Corrêa, Anne Aline Pereira de Paiva, Hegger Fritsch, Maria Angélica Mares-Guia, María Celeste Torres, Maurício Lima, Patrícia Carvalho de Sequeira, William de Almeida Marques, Jorlan Fernandes de Jesus, Felipe Gomes Naveca, Alessandra Lima da Silva, Anne Cybelle Pinto, Arun Kumar Jaiswal, Élisson Nogueira Lopes, Francielly Morais Rodrigues da Costa, Gabriel Quintanilha‐Peixoto, Gilson Carlos Soares, Paula Luize Camargos Fonseca, Renan P. Souza, Rodrigo Bentes Kato, Rodrigo Profeta Silveira Santos, Sandeep Tiwari, Wylerson Guimarães Nogueira, Beatriz Senra Álvares da Silva Santos, Bruna Lopes Bueno, Isadora Cristina de Siqueira, Lourdes Farre Vallve, Melina Mosquera Navarro Borba, Alix Sandra Mazzetto, Francisco de Assis Araújo Aguiar, Irenio da Silva Gomes, Jayra Juliana Paiva Alves Abrantes, Luiz Takao Watanabe, Marta Ferreira da Silva Rego, Vanessa Brandão Nardy, Shirlei Ferreira de Aguiar, Fabiana Cristina Pereira dos Santos, Alice Louize Nunes Queiroz, Bruno Tardelli Diniz Nunes, Lívia Carício Martins, Márcio Roberto Teixeira Nunes, Flavia Cristina da Silva Sales, Ingra Morales Claro, Jaqueline Góes de Jesus, Darlan da Silva Cândido, Cintia Fabbri, Claudia González, Lisseth Saéz, María Chen-Germán, Jaime Lagos Barrera, José Ernesto Ramírez–González, Josefina Campos, Noelia Morel Faller, Marta Eugenia Víquez Villalobos, Roberto Kaslin, Silvia Paola Salgado Cisneros, Flávia Figueira Aburjaile, Carolina Dourado Amaral, Danielle Bandeira Costa de Sousa Freire, Laura N. Cruz, Daniel Mattos, Leandro Ferreira Lopes Landeira, Mariane Talon de Menezes, Iêda M. Orioli, Ariane Coelho Ferraz, Daiane Teixeira de Oliveira, Alexandre Barbosa Reis, Renata Guerra de Sá Cota, Rafael dos Santos Bezerra, Melissa Barreto Falcão, Rodrigo Dias de Oliveira Carvalho, Edward C. Holmes, Túlio de Oliveira, José Lourenço, Luíz Carlos Júnior Alcântara,
Brazil experienced a large dengue virus (DENV) epidemic in 2019, highlighting a continuous struggle with effective control and public health preparedness. Using Oxford Nanopore sequencing, we led field and classroom initiatives for the monitoring of DENV in Brazil, generating 227 novel genome sequences of DENV1-2 from 85 municipalities (2015-2019). This equated to an over 50% increase in the number of DENV genomes from Brazil available in public databases. Using both phylogenetic and epidemiological ...
Tópico(s): Fish biology, ecology, and behavior
2021 - Nature Portfolio | Nature Communications

Lucas Gomes Santos, Regicley Vieira da Silva, Thiago Cavalcanti Leal, José Emerson Xavier, Elaine Virgínia Martins de Souza Figueiredo, João Paulo Silva de Paiva, Leonardo Feitosa da Silva, Carlos Alberto de Oliveira Rocha, Bruno Eduardo Bastos Rolim Nunes, Gibson Barros de Almeida Santana, Tânia Rita Moreno de Oliveira Fernandes, Francisco de Assis Costa, Márcio Bezerra‐Santos, Rodrigo Feliciano do Carmo, Anderson da Costa Armstrong, Carlos Dornels Freire de Souza,
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic in Brazil, several government policies have been taken. Herein, we aimed to assess the impact of the COVID-19 pandemic on hospital admissions and in-hospital lethality for cardiovascular diseases (CVD) in Brazil in 2020. An ecological and time-series study on hospitalizations and deaths from CVD in Brazil was conducted from January 2018 to December 2020.The hospital admission rate for CVD reduced by 17.1%, with a significant decreasing ...
Tópico(s): Healthcare cost, quality, practices
2022 - Elsevier BV | Current Problems in Cardiology

Pedro H. Doleski, Daniela Bitencourt Rosa Leal, Vanessa S. Machado, Nathieli B. Bottari, Émerson André Casali, César Eduardo Jacintho Moritz, Giovana Camillo, Fernanda F. Vogel, Lenita M. Stefani, Aleksandro Schafer da Silva,
The aim of this study was to evaluate the levels of purine nucleosides and xanthine oxidase (XO) activity in the liver of mice chronically infected by Toxoplasma gondii and treated with diphenyl diselenide (PhSe)2. For this experiment, forty Swiss mice were used. Twenty animals were orally infected by approximately 50 bradizoites of a cystogenic ME-49 strain of T. gondii, and the same number of uninfected mice was used as a control group. Ten infected and ten uninfected mice were subcutaneously treated ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2017 - Elsevier BV | Microbial Pathogenesis

Antônio Linkoln Alves Borges Leal, Antônio Júdson Targino Machado, Camila Fonseca Bezerra, Cicero Emerson Serra Inácio, Janaína Esmeraldo Rocha, Débora Lima Sales, Thiago Sampaio de Freitas, Waltécio de Oliveira Almeida, Wanderlei do Amaral, Luiz Everson da Silva, Áurea Portes Ferriani, Beatriz Helena Lameiro de Noronha Sales Maia, Maria Flaviana Bezerra Morais‐Braga, Humberto Medeiros Barreto, Henrique Douglas Melo Coutinho,
The family Piperaceae is known for presenting in its species flavoring, healing and antimicrobial properties among others. The objective of the present study was: to study the chemical profile of the essential oil of Piper rivinoides (EOPR); to analyze its anti-bacterial and antifungal potential, as well as to evaluate the antifungal and antibiotic-modifying capacity. The chemical constituents were identified by gas chromatography with flame ionization detector (GC-FID), allowing the identification ...
Tópico(s): Insect Pest Control Strategies
2019 - Elsevier BV | Food and Chemical Toxicology

Lucas Trevisan Gressler, Aleksandro S. Da Silva, Camila Belmonte Oliveira, Andressa S. Schafer, Adelina Rodrigues Aires, José Rocha, Alexandre A. Tonin, Gabriel Henrique Schirmbeck, Émerson André Casali, Sônia T.A. Lopes, Marta L.R. Leal, Sílvia González Monteiro,
SUMMARY The aim of this study was to evaluate the purine levels of lambs experimentally infected with Haemonchus contortus . A total of 12 healthy lambs were divided into two groups, composed of 6 animals each: Group A represented the healthy animals (uninfected), while in Group B the animals were infected with 15 000 larvae of H. contortus . Blood was drawn on days 15, 45 and 75 post-infection (PI) in order to perform the purine analysis (ATP, ADP, AMP, adenosine, inosine, hypoxanthine, xanthine and uric ...
Tópico(s): Coccidia and coccidiosis research
2014 - Cambridge University Press | Parasitology

Filipe Leal Portilho, Suyene Rocha Pinto, Aline Oliveira da Silva de Barros, Edward Helal‐Neto, Sofia Nascimento dos Santos, Emerson Soares Bernardes, Derya İlem‐Özdemir, Makbule Aşıkoğlu, Luciana Magalhães Rebêlo Alencar, Clenilton Costa dos Santos, Eduardo Ricci‐Júnior, Félix Sancenón, Ramón Martínez‐Máñez, Ralph Santos‐Oliveira,
Breast cancer is women's most common type of cancer, with a global rate of over 522,000 deaths per year. One of the main problems related to breast cancer relies in the early detection, as the specialized treatment. In this direction was developed, characterized and tested in vivo a smart delivery system, based on radiolabelled magnetic core mesoporous silica doped with trastuzumab as intralesional nanodrug for breast cancer imaging and possible therapy. The results showed that nanoparticles had ...
Tópico(s): Cancer Cells and Metastasis
2018 - Informa | Artificial Cells Nanomedicine and Biotechnology

Renata da Silva Pereira Saccol, Karine Lanes da Silveira, Alessandra G. Manzoni, Fátima Husein Abdalla, Juliana Sorraila de Oliveira, Guilherme Lopes Dornelles, Fernanda Barbisan, Daniela F. Passos, Émerson André Casali, Cínthia Melazzo de Andrade, Ivana Beatrice Mânica da Cruz, Daniela Bitencourt Rosa Leal,
Abstract Rheumatoid arthritis is a highly debilitating inflammatory autoimmune disease which is characterized by joint destruction. The present study sought to investigate the effect of quercetin in rats with complete Freund's adjuvant‐induced arthritis. Animals were divided into control/saline, control/quercetin (5 mg/kg, 25 mg/kg, and 50 mg/kg) arthritis/saline, and arthritis/quercetin (5 mg/kg, 25 mg/kg, and 50 mg/kg); the treatments were administered for 45 days. Biochemical, oxidative stress, ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2019 - Wiley | Journal of Cellular Biochemistry

Pedro H. Doleski, Daniela Bitencourt Rosa Leal, Vanessa S. Machado, Nathieli B. Bottari, Alessandra G. Manzoni, Émerson André Casali, César Eduardo Jacintho Moritz, Ana C. A. Rocha, Giovana Camillo, Fernanda F. Vogel, Lenita M. Stefani, Ricardo E. Mendes, Aleksandro Schafer da Silva,
The aim of this study was to verify the effect of diphenyl diselenide (PhSe)2 on hepatic nucleotidases and on the concentration of purines in mice infected by Toxoplasma gondii. The animals were divided into four groups: Group A (uninfected), Group B (uninfected and treated with (PhSe)2), Group C (infected), and Group D (infected and treated with (PhSe)2). The inoculation (groups C and D) was performed with 50 cysts of T. gondii (ME-49 strain). Mice from groups B and D were treated with 5 μmol kg-1 of (PhSe) ...
Tópico(s): Sulfur Compounds in Biology
2017 - Springer Science+Business Media | Purinergic Signalling

Geovani de Oliveira Ribeiro, Danielle Elise Gill, Edcelha Soares D’Athaide Ribeiro, Fred Júlio Costa Monteiro, Vanessa dos Santos Morais, Roberta Marcatti, Márlisson Octávio da Silva Rêgo, Emerson Luiz Lima Araújo, Steven S. Witkin, Fabiola Villanova, Xutao Deng, Éster Cerdeira Sabino, Eric Delwart, Élcio Leal, Antônio Charlys da Costa,
Dengue virus (DENV) is a mosquito-borne viral pathogen that plagues many tropical-climate nations around the world, including Brazil. Molecular epidemiology is a growing and increasingly invaluable tool for understanding the dispersal, persistence, and diversity of this impactful virus. In this study, plasma samples (n = 824) from individuals with symptoms consistent with an arboviral febrile illness were analyzed to identity the molecular epidemiological dynamics of DENV circulating in the Brazilian ...
Tópico(s): Dengue and Mosquito Control Research
2021 - Multidisciplinary Digital Publishing Institute | Viruses

Renata da Silva Pereira Saccol, Karine Lanes da Silveira, Stephen A. Adefegha, Alessandra G. Manzoni, Leonardo Lanes da Silveira, Ana Paula V. Coelho, Lívia G. Castilhos, Fátima Husein Abdalla, Lara Vargas Becker, Nara Maria Beck Martins, Juliana Sorraila de Oliveira, Émerson André Casali, Daniela Bitencourt Rosa Leal,
The effect of quercetin was assessed in rats induced with complete Freund adjuvant (CFA). Arthritis scores, paw oedema, latency, activities of myeloperoxidase (MPO), ectonucleoside triphosphate diphosphohydrolase (E‐NTPDase), and ectoadenosine deaminase (E‐ADA) in lymphocytes were determined. Furthermore, nucleotide and nucleoside levels as well as the secretion of pro‐ and anti‐inflammatory cytokines were evaluated. Animals were treated with saline and quercetin in doses of 5, 25, and 50 mg/kg for ...
Tópico(s): Quinazolinone synthesis and applications
2019 - Wiley | Cell Biochemistry and Function

Edson Lourenço da Silva, Adriana Josefa da Rocha, Manuella Feitosa Leal, Orianna dos Santos, João Hemerson de Sousa, Antônia Rafaela Viana da Silva, Karina Ketelen Silva Dantas, Erika Maria Matos Rulim, Emerson Santos Castro, Ana Carolina Landim Pacheco, Tamaris Gimenez Pinheiro,
Abstract: The pronounced dry season determines the characteristics of the semiarid region of Brazil. Numerous small reservoirs are built to overcome this condition, accumulating multiple uses and causing important changes in the landscape and the local biota. Considering the limited amount of information about the malacofauna of reservoirs, mainly in the Northeast region of the country, this inventory provides a list of mollusks from three important reservoirs located in the city of São Julião, ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2019 - Fundação de Amparo à Pesquisa do Estado de SP | Biota Neotropica

Alex Soares da Silva, Emerson Mariano da Silva, João Bosco Verçosa Leal, Domingo Cassain Sales, Icaro Jael Mendonça Moura, José Maria Brabo Alves,
Resumo Os Distúrbios Ondulatórios de Leste (DOLs) são um dos principais sistemas meteorológicos que atuam no leste do Nordeste do Brasil (NEB) entre maio e julho. O presente estudo tem como objetivo investigar os impactos das diferentes técnicas de nudging na simulação de DOLs utilizando o modelo regional Weather Research and Forecasting (WRF) a partir de três diferentes tipos de simulação, alternando entre elas diversas possibilidades do uso desta técnica: (1) utilizando o nuding de forma desligada ( ...
Tópico(s): Precipitation Measurement and Analysis
2021 - Sociedade Brasileira de Meteorologia | Revista Brasileira de Meteorologia

Manuella Feitosa Leal, Luiz Ricardo L. Simone, Emerson Santos Castro, Orianna dos Santos, ANTÔNIA R.V. DA SILVA, Karina Ketelen Silva Dantas, João Hemerson de Sousa, Edson Lourenço da Silva, Tamaris Gimenez Pinheiro, Ana Carolina Figueiredo Lacerda,
Despite the great diversity, economic and environmental importance of limnic mollusks, the group is still little investigated in the Brazilian semiarid region, especially in the state of Piauí. Thus, this work aims to gather information on the diversity of limnic mollusks in the Brazilian Northeast and the semiarid region, including new records for the state of Piauí, northeastern Brazil. For this, collections in the urban perimeter of the Itaim and Guaribas Rivers, municipalities of Itainópolis, ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2021 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências

Carlos Roberto Fonseca, Gislene Ganade, Ronei Baldissera, C. Guilherme Becker, Carlos Renato Boelter, Antônio D. Brescovit, Lucas M. Campos, Tomás Fleck, Vanda Simone da Silva Fonseca, Sandra Maria Hartz, Fernando Joner, Márcia Isabel Käffer, Ana María Leal-Zanchet, Marcelo Pinto Marcelli, Alex Mesquita, Cláudio Augusto Mondin, Cláudia Cristina Paro de Paz, Maria Virgı́nia Petry, Fabio N. Piovensan, Jair Putzke, Anamaria Stranz, Micheline Vergara, Emerson Monteiro Vieira,
Since pristine Atlantic Forest remnants are vanishing, and biological reserves are in short, conservation of biodiversity will largely depend on proper management of the anthropogenic matrix. Here, we test (1) the effectiveness of ecologically-managed tree monocultures in maintaining Araucaria Forest biodiversity, (2) how this effectiveness change among taxa, and (3) we discuss management principles that can be used by the forestry industry in order to contribute positively to biodiversity conservation. ...
Tópico(s): Lichen and fungal ecology
2009 - Elsevier BV | Biological Conservation

Marcelle Silva‐Sales, Élcio Leal, Flavio Augusto de Pádua Milagres, Rafael Brustulin, Vanessa dos Santos Morais, Roberta Marcatti, Emerson Luiz Lima Araújo, Steven S. Witkin, Xutao Deng, Éster Cerdeira Sabino, Eric Delwart, Adriana Luchs, Antônio Charlys da Costa,
Surveillance of Rotavirus A (RVA) throughout the national territory is important to establish a more complete epidemiological-molecular scenario of this virus circulation in Brazil. The aim of the present study was to investigate the genetic diversity of RVA strains circulating in Tocantins State (Northern Brazil) during six years of post-vaccination follow-up (2010-2016). A total of 248 stool samples were screened by next generation sequencing and 107 (43.1%) nearly full length RVA genome sequences ...
Tópico(s): Animal Virus Infections Studies
2020 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo

Natanael Vieira de Sousa, Adaiana F. Gomes da Silva, Gilberto Ferno Fisch, João Bosco Verçosa Leal, Roberto Fernando da Fonseca Lyra, Emerson Mariano da Silva,
Resumo Este trabalho tem como objetivo avaliar duas simulações do modelo WRF que diferem em sua parametrização da Camada Limite Planetária (CLP). Foram utilizados dados de 72 radiossondas lançadas em Fortaleza (CE) entre 5 e 25 de Abril de 2011 nos horários sinóticos. A altura da CLP foi a variável avaliada e os valores observados, calculados pelo método do gradiente vertical da temperatura potencial, foram de 245±28 m para o período noturno e de 925±63 m para o período diurno. As parametrizações ...
Tópico(s): Atmospheric aerosols and clouds
2019 - Sociedade Brasileira de Meteorologia | Revista Brasileira de Meteorologia

Geovani de Oliveira Ribeiro, Danielle Elise Gill, Endrya do Socorro Fôro Ramos, Fabiola Villanova, Edcelha Soares D’Athaide Ribeiro, Fred Júlio Costa Monteiro, Vanessa dos Santos Morais, Márlisson Octávio da Silva Rêgo, Emerson Luiz Lima Araújo, Ramendra Pati Pandey, V. Samuel Raj, Xutao Deng, Eric Delwart, Antônio Charlys da Costa, Élcio Leal,
The simultaneous transmission of two lineages of the chikungunya virus (CHIKV) was discovered after the pathogen's initial arrival in Brazil. In Oiapoque (Amapá state, north Brazil), the Asian lineage (CHIKV-Asian) was discovered, while in Bahia state, the East-Central-South-African lineage (CHIKV-ECSA) was discovered (northeast Brazil). Since then, the CHIKV-Asian lineage has been restricted to the Amazon region (mostly in the state of Amapá), whereas the ECSA lineage has expanded across the country. ...
Tópico(s): Malaria Research and Control
2022 - Multidisciplinary Digital Publishing Institute | Viruses