Emma Nilsson, Helena Salonen Ros, Sven Cnattingius, Paul Lichtenstein,
Objectives To determine the importance of genetic effects in the aetiology of pre‐eclampsia and gestational hypertension and to investigate whether pre‐eclampsia and gestational hypertension share genetic aetiology. Design Individual record linkage between the population‐based Swedish Multi‐Generation and the Medical Birth Registers. Setting Sweden. Population 1,188,207 births between 1987 and 1997 and their parents. Methods Similarities in relatives were measured by the number of pairs concordant ...
Tópico(s): Gestational Diabetes Research and Management
2004 - Wiley | BJOG An International Journal of Obstetrics & Gynaecology
Emma Nilsson, Helena Igelström, Irene Vikman, Agneta Larsson, Mascha Pauelsen,
Self-perceptions of aging (SPA) is associated with various health-related outcomes, including physical performance. No previous study has investigated the potential predictive influence of SPA on physical performance among Swedish community-dwelling older adults. This was a cross-sectional study using a random sample of 153 Swedish community-dwelling individuals aged 70 and older. Multiple logistic regression analysis was performed, using the subscale “Attitude Towards Own Aging” of the Philadelphia ...
Tópico(s): Physical Activity and Health
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Annika Bergquist, Tobias J. Weismüller, Cynthia Levy, Christian Rupp, Deepak Joshi, Jeremy Nayagam, Aldo J. Montaño‐Loza, Ellina Lytvyak, Ewa Wunsch, Piotr Milkiewicz, Roman Zenouzi, Christoph Schramm, Nora Cazzagon, Annarosa Floreani, Ingalill Friis Liby, Miriam Wiestler, Heiner Wedemeyer, Taotao Zhou, Christian P. Strassburg, Eirini I. Rigopoulou, George Ν. Dalekos, Manasa Narasimman, Xavier Verhelst, Helena Degroote, Mette Vesterhus, Andreas E. Kremer, Bennet Bündgens, Fredrik Rorsman, Emma Nilsson, Kristin Kaasen Jørgensen, Erik von Seth, Martin Cornillet, Nils Nyhlin, Harry Martin, Stergios Kechagias, Kristine Wiencke, Mårten Werner, Benedetta Terziroli Beretta‐Piccoli, Marco Marzioni, Helena Isoniemi, Johanna Arola, Agnes Wefer, Jonas Söderling, Martti Färkkilâ, Henrike Lenzen,
Abstract Background & Aims Evidence for the benefit of scheduled imaging for early detection of hepatobiliary malignancies in primary sclerosing cholangitis (PSC) is limited. We aimed to compare different follow‐up strategies in PSC with the hypothesis that regular imaging improves survival. Methods We collected retrospective data from 2975 PSC patients from 27 centres. Patients were followed from the start of scheduled imaging or in case of clinical follow‐up from 1 January 2000, until death or last ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2022 - Wiley | Liver International
Tina Rönn, Petr Volkov, Cajsa Davegårdh, Tasnim Dayeh, Elin Hall, Anders H. Olsson, Emma Nilsson, Åsa Tornberg, Marloes Dekker Nitert, Karl‐Fredrik Eriksson, Helena A. Jones, Leif Groop, Charlotte Ling,
Epigenetic mechanisms are implicated in gene regulation and the development of different diseases. The epigenome differs between cell types and has until now only been characterized for a few human tissues. Environmental factors potentially alter the epigenome. Here we describe the genome-wide pattern of DNA methylation in human adipose tissue from 23 healthy men, with a previous low level of physical activity, before and after a six months exercise intervention. We also investigate the differences ...
Tópico(s): RNA modifications and cancer
2013 - Public Library of Science | PLoS Genetics
Amra Jujić, Christopher Godina, Mattias Belting, Olle Melander, Jens J. Holst, Emma Ahlqvist, Maria F. Gomez, Peter M. Nilsson, Helena Jernström, Martin Magnusson,
Abstract Concerns have been raised regarding a potentially increased risk of cancer associated with treatment with glucagon-like peptide-1 (GLP-1) receptor agonists. Here, we explored whether fasting and oral glucose tolerance test post-challenge glucose-dependent insulinotropic peptide (GIP) and GLP-1 levels were associated with incident first cancer. Within the cardiovascular re-examination arm of the population-based Malmö Diet Cancer study (n = 3734), 685 participants with a previous cancer diagnosis ...
Tópico(s): Gastric Cancer Management and Outcomes
2023 - Nature Portfolio | Scientific Reports
Anna Lindstrand, Marlene Ek, Malin Kvarnung, Britt‐Marie Anderlid, Erik Björck, Jonas Carlsten, Jesper Eisfeldt, Giedré Grigelioniené, Peter Gustavsson, Anna Hammarsjö, Hafdís T. Helgadóttir, Maritta Hellström-Pigg, Ekaterina Kuchinskaya, Kristina Lagerstedt‐Robinson, Lars‐Åke Levin, Agne Liedén, Hillevi Lindelöf, Helena Malmgren, Daniel Nilsson, Eva Svensson, Martin Paucar, Ellika Sahlin, Bianca Tesi, Emma Tham, Johanna Winberg, Max Winerdal, Josephine Wincent, Maria Soller, Maria Pettersson, Ann Nordgren,
Individuals with intellectual disability (ID) and/or neurodevelopment disorders (NDDs) are currently investigated with several different approaches in clinical genetic diagnostics.We compared the results from 3 diagnostic pipelines in patients with ID/NDD: genome sequencing (GS) first (N = 100), GS as a secondary test (N = 129), or chromosomal microarray (CMA) with or without FMR1 analysis (N = 421).The diagnostic yield was 35% (GS-first), 26% (GS as a secondary test), and 11% (CMA/FMR1). Notably, the age of diagnosis ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2022 - Elsevier BV | Genetics in Medicine
Emma Tham, Erik A. Eklund, Anna Hammarsjö, Per Bengtson, Stefan Geiberger, Kristina Lagerstedt‐Robinson, Helena Malmgren, Daniel Nilsson, Gintautas Grigelionis, Peter Conner, Peter Lindgren, Anna Lindstrand, Anna Wedell, Margareta Albåge, K Zielińska, Ann Nordgren, Nikos Papadogiannakis, Gen Nishimura, Giedré Grigelioniené,
A rare lethal autosomal recessive syndrome with skeletal dysplasia, polycystic kidneys and multiple malformations was first described by Gillessen-Kaesbach et al and subsequently by Nishimura et al. The skeletal features uniformly comprise a round pelvis, mesomelic shortening of the upper limbs and defective ossification of the cervical spine. We studied two unrelated families including three affected fetuses with Gillessen-Kaesbach–Nishimura syndrome using whole-exome and Sanger sequencing, comparative ...
Tópico(s): Infant Nutrition and Health
2015 - Springer Nature | European Journal of Human Genetics
Anna Lindstrand, Jesper Eisfeldt, Maria Pettersson, Claudia M.B. Carvalho, Malin Kvarnung, Giedré Grigelioniené, Britt‐Marie Anderlid, Olof Bjerin, Peter Gustavsson, Anna Hammarsjö, Patrik Georgii‐Hemming, Erik Iwarsson, Maria Soller, Kristina Lagerstedt‐Robinson, Agne Liedén, Måns Magnusson, Marcel Martin, Helena Malmgren, Magnus Nordenskjöld, Ameli Norling, Ellika Sahlin, Henrik Stranneheim, Emma Tham, Josephine Wincent, Sofia Ygberg, Anna Wedell, Valtteri Wirta, Ann Nordgren, Johanna Lundin, Daniel Nilsson,
Abstract Background Since different types of genetic variants, from single nucleotide variants (SNVs) to large chromosomal rearrangements, underlie intellectual disability, we evaluated the use of whole-genome sequencing (WGS) rather than chromosomal microarray analysis (CMA) as a first-line genetic diagnostic test. Methods We analyzed three cohorts with short-read WGS: (i) a retrospective cohort with validated copy number variants (CNVs) (cohort 1, n = 68), (ii) individuals referred for monogenic multi- ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2019 - BioMed Central | Genome Medicine
Anna-Maria Wahlberg, Magdalena Alenström, Stina Udin, Tore Johansson, Anna Karin Lundgren, Birgitta Romany Johansson, Carin Ekström, Nils E. Eriksson, L.P. Andersson, H. Eklund, Lotta Robertsson, Gunilla Bjerhag, Ann-Charlotte Gustavsson, Madelene Israelsson, Sofia Karlsson, M. Westerlund, Yvonne Ek, Birgitta Stenbäck, Barbro Andersson, Elisabeth Elgmark Andersson, Kristina Leppämäki, Anette Ramirez, Victoria Wallin, Alexandra Lundberg, Benny Sahlin, Hasse Mälberg, Maria Liljeroos, Caroline Gustafsson, K Nyström, Susanne Siklo, Eva Zelleroth, Finn Hjortevang, Kamaran Mohammed, Agneta Hellblad, Iwona Schön, Kristina Carlsson, Marita Ole ́rs, Pär Lennart Ågren, Iwar Sjögren, Crister Zedigh, Kristina Eriksson, Kristina Sundkvist, Anna-Karin Thorsell, Ann-Kristin Kuoljok, Linda Liinanki, Mona Liljergren, Sara Turtola, Britt-Marie Nylander, Lena Nordvall, Malin Nilsson, Annelie Blomqvist, H. E. Sjöberg, Jenny Nylander, Linda Berglund, Linda Mossberg, Lars Svennberg, Espen Haugen, Lars Hellsten, Staffan Johansson, Birgitta Johansson, Pethra Larsson, Susanne Kellerth, Monika Bergström, Carola Gustafsson, Cecilia Nährström, Eva Evenås, Hanna Sundin, Helena Lönn, Johan Svensson, Moa Kihlgren, Per Larsson, Pirjo Palosaari, Susann Johansson, Malin Cedermark magnusson, Annica Ravn‐Fischer, Ann Wittfeldt, Elisabeth Perers, Nina Hellberg, Mikael Holmberg, Bert Andersson, Berit Jangsten, Nedim Selimović, Anna Enström, Göran Dellgren, Henrik Scherstén, Anna Biveby-Nilsson, Johan Lundberg, Elmir Ömerovic, Pétur Pétursson, Per Albertsson, Carina Ankarstrand, Agneta Flinck, Titti Larsson, Maria Samuelsson, Peter Bergman, Lotten Nyström, Magnus Bågenholm, Anneli Linnér, Björn Hornestam, Helén Sjöland, Anne-Marie Kirkhoff, Hugo Månsson, Ida Karlsson, Maria Olausson, Charlotte Berne, Christina Backe, Ali Tabandeh, Ann-Charlotte Karlsson, Peter Hårdhammar, S. Bertil Olsson, Henrik Persson, Ole Wagner, Henrik Wagner, Lennart Sandhall, Carina Wåhlander, Kristina Rova, Lina Fischer, Maria Nilsson, Mari Stjernberg, Sylvia Gustavsson, Camilla Hedberg, Jan Thollander, Katarina Collberg, Jörg Lauermann, Werner Puskar, Margareta Larsson, Ann Johansson, Lina Brindstedt, M. Olofsson, J. Carlsson, Katarina Månsson, Ulla Jeppsson, Ingbritt Söderlind, Malinn Hultman, Sara Ronnelin, Carina Fredriksson, Gerd Skogman, Ingela Ågren, Inger Almroth, Sara Trege Nilsson, Gerd Pettersson, I. Åkesson, Sofia Carlfelter, Jan Medin, Karim Mokhtar, Carl‐Magnus Pripp, Linda Malmsten, Annelie Karlsson, Anna Lenberg, Annika Lettenström, Anna Jost-Widén, Gunilla Johnson, Håkan Ahlmark, Hannah Brevik, IngaLill Nordberg, Jessica Österberg-Persson, Jeanette Smedberg, Maria Eklund, Urban Haaga, A. Henriksson, Mats Allared, Hans Olsson, Tage Nilsson, Lisa Juhlin, Karin Eriksson, Leif Hedquist, Ulla Lundin, Christin Jonsson, Monica Pedersen, Julia Marainen, Moa Bylund, Monica Alsterdal, Anna Sjöberg, Ewa Wigenstorp, Gunilla Peterzen, Kerstin Skeppstedt, Anette Berlin, Helena Wikström, K. Pihl, Lehna Ferm, Petra Larsson, Vanja Johansson, Gunvor Finnas, Helen Ahlm, Anders Ekelind, Eva Hallgren Larsson, Gull-Britt Eriksson, Veronica Sass, Åsa Johansson, Lennart Malmqvist, Lars Westin, Eydis Sigurjonsdottir, F Bjork Skuladottir, Maria Ottesen, O. Bjarnadottir, Gunnar Mýrdal, Edda Traustadottir, Friðrika Sigvaldadóttir, Gerður Garðarsdóttir, Gudrun Valgeirsdottir, Sigurlaug Magnusdottir, Thora Bjornsdottir, Þórarinn Guðnason, Svava Matthiasdottir, Maria Jonsson, U. Pettersson, Magnus Peterson, Karin Molander, Micael Larsson, Berit Samuelsson, C. Svensson, Elisabeth Augustsson, Evelin BertilssonFröjd, Joakim Alfredsson, Wolfgang Freter, L.G. Lilja, Gunnel Andersson, Dimitrios Venetsanos, Anders Björkholm, Tim Tödt, Ulf Berglund, Niels Erik Nielsen, Jenny Johansson, Johanna Svensson, Rosie-Marie Larsson, Liselotte Lundmark, Gunilla Brolin, Annika Westergren, Anna Duckert, Vesna Steffan, Matthias Götberg, David Erlinge, Fredrik Scherstén, Göran Olivecrona, Jan Harnek, Per Bondesson, Pernilla Knutsson, Evy Stenlund, Peter Thorén, Siv Algotsson, Enisa Durakovic, Lisa Gustafsson, Marie Nilsson, Margareta Nilson, Pallonji Bhiladvala, Monica Håkansson, Carina Svensson, Ingela Olsson, Amelie Kjellstenius, Jenny Åslund, Linnéa Alledal, Nina Varblane, Victoria Nilsson, Maria Thudén, S. Liaaen Jensen, Elisabet Svensson, Maria Pettersson, S. Lindgren, Anita Pehrsson, Elisabet Svensson, Maria Olsson, Anneli Rudenäs, Eva Öhman, Stig-Åke Falk, Annelie Jaensson, Lena Thell, Annette Billqvist, Barbro Efraimsson-Nilsson, Ingalill Allansson, Malin Jansson, Ann Ingström, Christina Lundqvist, Ingela Nyström, Ingrid Bergman, J. Ekman, Lena Carlson, S. Person, Ingrid Lindberg, Leif Thuesen, E. Lindberg, Gunnilla Lundberg, Kerstin Hedberg, Inga-Lill Kotka, A. Fogelberg, A. Malin Johansson, Lis Ståhl, Anders Kallryd, Agneta Ramén, Henrik Löfmark, Senait Fessahaie, Malin Brandrup-Wognsen, Claire Salomonsson, Petra Ardin, Eva Balcker, Filippa Högberg, Fredrik Högberg,
According to Swedish National Board of Health and Welfare statistics, a dramatic decrease in both the incidence of and mortality from acute myo-cardial infarction has been seen in the past two deca...
Taylor & Francis
Jacob W. Vogel, Yasser Iturria‐Medina, Olof Strandberg, Ruben Smith, Elizabeth Levitis, Alan C. Evans, Oskar Hansson, Michael W. Weiner, Paul Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John R. Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Michael Donohue, Matt A. Bernstein, Nick C. Fox, Paul M. Thompson, Norbert Schuff, Charles DeCarli, Bret Borowski, Jeff Gunter, Matthew L. Senjem, Prashanthi Vemuri, David T. Jones, Kejal Kantarci, Chad Ward, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chester A. Mathis, Susan Landau, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Virginia M.‐Y. Lee, Magdalena Korecka, Michal Figurski, Karen Crawford, Scott Neu, Tatiana Foroud, Steven G. Potkin, Li Shen, Kelley Faber, Sungeun Kim, Kwangsik Nho, Zaven Kachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph F. Quinn, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James M. Brewer, Helen Vanderswag, Adam Fleisher, Judith L. Heidebrink, Joanne Lord, Ronald C. Petersen, Sara S. Mason, Colleen S. Albers, David S. Knopman, Kris Johnson, Rachelle S. Doody, Javier Villanueva Meyer, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, Beau M. Ances, John C. Morris, Maria Carroll, Sue Leon, Erin Householder, Mark A. Mintun, Stacy Schneider, Angela OliverNG, Randall Griffith, David W. Clark, David Geldmacher, John Brockington, Erik D. Roberson, Hillel Grossman, Effie Mitsis, Leyla de Toledo‐Morrell, Raj C. Shah, Ranjan Duara, Daniel Varón, Maria T. Greig, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Daniel D’Agostino, Stephanie Kielb, James E. Galvin, Dana M. Pogorelec, Brittany Cerbone, Christina A. Michel, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, Terence Z. Wong, Steven E. Arnold, Jason H. Karlawish, David A. Wolk, Charles D. Smith, Gregory A. Jicha, Peter Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad, Oscar L. López, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc Adams Ortiz, Kyle Womack, Dana Mathews, Mary Quiceno, Ramon Diaz Arrastia, Richard King, Myron Weiner, Kristen Martin Cook, Michael D. Devous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S. Anderson, Russell H. Swerdlow, Liana Apostolova, Kathleen Tingus, Ellen Woo, Daniel Silverman, Po H. Lu, George Bartzokis, Neill R. Graff Radford, Francine Parfitt, Tracy Kendall, Heather Johnson, Martin R. Farlow, Ann Marie Hake, Brandy R. Matthews, Scott Herring, Cynthia Hunt, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra E. Black, Bojana Stefanovic, Curtis Caldwell, Ging‐Yuek Robin Hsiung, Howard Feldman, Benita Mudge, Michele Assaly Past, Andrew Kertesz, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek Marsel Mesulam, Kristine Lipowski, Chuang Wu, Nancy E. Johnson, Carl Sadowsky, Walter Martínez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Jerome A. Yesavage, Joy L. Taylor, Barton Lane, Allyson Rosen, Jared Tinklenberg, Marwan N. Sabbagh, Christine M. Belden, Sandra A. Jacobson, Sherye A. Sirrel, Neil W. Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Joanne Allard, Alan J. Lerner, Paula Ogrocki, Leon Hudson, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T. Y. Lee, Robert Bartha, Sterling C. Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven Potkin, Adrian Preda, Dana Nguyen, Pierre N. Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Douglas W. Scharre, Maria Kataki, Anahita Adeli, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Robert B. Santulli, Tamar J. Kitzmiller, Eben S. Schwartz, Kaycee M. SinkS, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Kenneth Spicer, David Bachman, Elizabeth Finger, Stephen Pasternak, Irina Rachinsky, John Rogers, Andrew Kertesz, Dick Drost, Nunzio Pomara, Raymundo Hernando, Antero Sarrael, Susan K. Schultz, Laura L. Boles Ponto, Hyungsub Shim, Karen E. Smith, Norman Relkin, Gloria Chaing, Lisa Raudin, Amanda Smith,
Abstract Tau is a hallmark pathology of Alzheimer’s disease, and animal models have suggested that tau spreads from cell to cell through neuronal connections, facilitated by β -amyloid (A β ). We test this hypothesis in humans using an epidemic spreading model (ESM) to simulate tau spread, and compare these simulations to observed patterns measured using tau-PET in 312 individuals along Alzheimer’s disease continuum. Up to 70% of the variance in the overall spatial pattern of tau can be explained by our ...
Nature Portfolio
Linn Nilsson, Emma Sandén, Somayeh Khazaei, Helga Tryggvadottir, Björn Nodin, Karin Jirström, Signe Borgquist, Karolin Isaksson, Helena Jernström,
Background: Activated signal transducer and activator of transcription 3 (pSTAT3) is often present in breast cancer, but its prognostic impact is still unclear. We investigated how breast tumor-specific pSTAT3Y705 levels are associated with patient and tumor characteristics and risk of recurrence. Materials and Methods: Primary breast cancer patients without preoperative treatment were included preoperatively. The patients were treated in Lund, Sweden, in 2002-2012 and followed until 2016. Levels ...
Tópico(s): Histone Deacetylase Inhibitors Research
2020 - Frontiers Media | Frontiers in Oncology
Linnea Huss, Igis Gulz-Haake, Emma Nilsson, Helga Tryggvadottir, Linn Nilsson, Björn Nodin, Karin Jirström, Karolin Isaksson, Helena Jernström,
Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, Sweden, included in the Breast Cancer and Blood Study (BCBlood) from October 2002 to June 2012. The follow- ...
Tópico(s): Estrogen and related hormone effects
2024 - Multidisciplinary Digital Publishing Institute | Nutrients
Emma M. Johansson, Pia Nilsson, Helena Hansson,
Tópico(s): Rural development and sustainability
2025 - Oxford University Press | European Review of Agricultural Economics
Troels Yndigegn, Thomas Gu, Helena Grufman, David Erlinge, Arash Mokhtari, Ulf Ekelund, Martin Magnusson, Emma Gustafsson, Jan Nilsson, Isabel Gonçalves, Alexandru Șchiopu,
Carbohydrate antigen 125 (CA125), a mucin produced by serosal cells in response to mechanical and inflammatory stimuli, has emerged as an important biomarker to guide risk stratification in heart failure (HF). The prognostic value of CA125 in acute coronary syndrome (ACS) patients is less explored.
Tópico(s): Hyperglycemia and glycemic control in critically ill and hospitalized patients
2024 - Wiley | ESC Heart Failure
Anna Lindstrand, Marlene Ek, Malin Kvarnung, Britt‐Marie Anderlid, Erik Björck, Jonas Carlsten, Jesper Eisfeldt, Giedré Grigelioniené, Peter Gustavsson, Anna Hammarsjö, Hafdís T. Helgadóttir, Maritta Hellström-Pigg, Ekaterina Kuchinskaya, Kristina Lagerstedt‐Robinson, Lars‐Åke Levin, Agne Liedén, Hillevi Lindelöf, Helena Malmgren, Daniel Nilsson, Eva Svensson, Martin Paucar, Ellika Sahlin, Bianca Tesi, Emma Tham, Johanna Winberg, Max Winerdal, Josephine Wincent, Maria Soller, Maria Pettersson, Ann Nordgren,
Tópico(s): Genetics and Neurodevelopmental Disorders
2023 - Elsevier BV | Pathology
Jacob W. Vogel, Yasser Iturria‐Medina, Olof Strandberg, Ruben Smith, Elizabeth Levitis, Alan C. Evans, Oskar Hansson, Michael W. Weiner, Paul Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Michael Donohue, Matt A. Bernstein, Nick C. Fox, Paul M. Thompson, Norbert Schuff, Charles DeCarli, Bret Borowski, Jeff Gunter, Matthew L. Senjem, Prashanthi Vemuri, David T. Jones, Kejal Kantarci, Chad Ward, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chester A. Mathis, Susan Landau, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Virginia M.‐Y. Lee, Magdalena Korecka, Michal Figurski, Karen Crawford, Scott Neu, Tatiana Foroud, Steven G. Potkin, Li Shen, Kelley Faber, Sungeun Kim, Kwangsik Nho, Zaven Kachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph F. Quinn, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James M. Brewer, Helen Vanderswag, Adam Fleisher, Judith L. Heidebrink, Joanne Lord, Ronald C. Petersen, Sara S. Mason, Colleen S. Albers, David S. Knopman, Kris Johnson, Rachelle S. Doody, Javier Villanueva Meyer, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, Beau M. Ances, John C. Morris, Maria Carroll, Sue Leon, Erin Householder, Mark A. Mintun, Stacy Schneider, Angela OliverNG, Randall Griffith, David W. Clark, David Geldmacher, John Brockington, Erik D. Roberson, Hillel Grossman, Effie Mitsis, Leyla de Toledo‐Morrell, Raj C. Shah, Ranjan Duara, Daniel Varón, Maria T. Greig, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Daniel D’Agostino, Stephanie Kielb, James E. Galvin, Dana M. Pogorelec, Brittany Cerbone, Christina A. Michel, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, Terence Z. Wong, Steven E. Arnold, Jason H. Karlawish, David A. Wolk, Charles D. Smith, Gregory A. Jicha, Peter Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad, Oscar L. López, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc Adams Ortiz, Kyle Womack, Dana Mathews, Mary Quiceno, Ramon Diaz Arrastia, Richard King, Myron Weiner, Kristen Martin Cook, Michael D. Devous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S. Anderson, Russell H. Swerdlow, Liana Apostolova, Kathleen Tingus, Ellen Woo, Daniel Silverman, Po H. Lu, George Bartzokis, Neill R. Graff Radford, Francine Parfitt, Tracy Kendall, Heather Johnson, Martin R. Farlow, Ann Marie Hake, Brandy R. Matthews, Scott Herring, Cynthia Hunt, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra E. Black, Bojana Stefanovic, Curtis Caldwell, Ging‐Yuek Robin Hsiung, Howard Feldman, Benita Mudge, Michele Assaly Past, Andrew Kertesz, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek Marsel Mesulam, Kristine Lipowski, Chuang Wu, Nancy E. Johnson, Carl Sadowsky, Walter Martínez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Jerome A. Yesavage, Joy L. Taylor, Barton Lane, Allyson Rosen, Jared Tinklenberg, Marwan N. Sabbagh, Christine M. Belden, Sandra A. Jacobson, Sherye A. Sirrel, Neil W. Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Joanne Allard, Alan J. Lerner, Paula Ogrocki, Leon Hudson, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T. Y. Lee, Robert Bartha, Sterling C. Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven G. Potkin, Adrian Preda, Dana Nguyen, Pierre N. Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Douglas W. Scharre, Maria Kataki, Anahita Adeli, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Robert B. Santulli, Tamar J. Kitzmiller, Eben S. Schwartz, Kaycee M. SinkS, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Kenneth Spicer, David Bachman, Elizabeth Finger, Stephen Pasternak, Irina Rachinsky, John Rogers, Andrew Kertesz, Dick Drost, Nunzio Pomara, Raymundo Hernando, Antero Sarrael, Susan K. Schultz, Laura L. Boles Ponto, Hyungsub Shim, Karen E. Smith, Norman Relkin, Gloria Chaing, Lisa Raudin, Amanda Smith,
Nature Portfolio
Saul N. Faust, Richard Haynes, Christine E. Jones, Natalie Staplin, Elizabeth Whittaker, Thomas Jaki, Ed Juszczak, Enti Spata, Mandy Wan, Alasdair Bamford, Paul Dimitri, Adam Finn, John Furness, Athimalaipet V Ramanan, Chris Gale, Katrina Cathie, Simon B. Drysdale, Jolanta Bernatoniene, Clare Murray, Charles Christoph Roehr, Paul Fleming, Andrew Riordan, Srini Bandi, Deepthi Jyothish, Jennifer Evans, Marieke Emonts, Dominic F. Kelly, Nazima Pathan, Patrick Davies, Rosie Hague, Louisa Pollock, Malcolm G. Semple, Leon Peto, J. Kenneth Baillie, Maya H Buch, Katie Jeffery, Marian Knight, Wei Shen Lim, Alan Montgomery, Aparna Mukherjee, Andrew Mumford, Kathy Rowan, Guy Thwaites, Marion Mafham, Jonathan Emberson, Martin Landray, Peter Horby, Lucy C. Chappell, Jeremy Day, DV Dung, Jeremy Day, NN Quang, Prof Binh, Erlina Burhan, Bachti Alisjahbana, Janak Koirala, S Basnet, Evelyne Kestelyn, Buddha Basnyat, Pradip Gyanwali, RL Hamers, Peter Sandercock, Janet Darbyshire, David L. DeMets, Robert Fowler, David G. Lalloo, Mohammed Munavvar, Ian Roberts, Adilia Warris, Janet Wittes, A Craddock-Bamford, Janet Barton, Ahmet Başoğlu, Rosemary Brown, Wojciech Brudlo, Emmanuelle Denis, Lucy Fletcher, Sarah Howard, Sabrina Musini, K. Taylor, Guanglin Cui, Bob Goodenough, Andy J. King, M Lay, David R. Murray, W. Grant Stevens, Karl Wallendszus, Robert C. Welsh, Charles Crichton, Jane C. Davies, Raph Goldacre, Charlie Harper, F Knight, Miles A. Nunn, Hizni Salih, John J. Welch, Mark Campbell, Guilherme Pessoa-Amorim, Mohamed A. Zayed, Jonathan D. Wiles, GRANT P. BAGLEY, Scott J. Cameron, Sarah Chamberlain, Barbara Farrell, Hannah Freeman, Ann R. Kennedy, Anne Whitehouse, Sara Wilkinson, Caroline Wood, Christina Reith, K Davies, Heather Halls, Lisa Holland, Robert Truell, Kevin C. Wilson, Emma Lingwood, L. Howie, Michael P. Lunn, Penelope Rodgers, John Amuasi, Kathleen Baird, Ting Bao, Buddha Basnyat, Mustapha Bittaye, Joseph Bonney, Umberto D’Alessandro, Meghnath Dhimal, Pradip Gyanwali, RL Hamers, T Huyen, Abubacarr Jagne, Abhilasha Karkey, Evelyne Kestelyn, Oumou Maïga, E Matey, Behzad Nadjm, Jeremy Nel, Suman Pant, Khairunnisa Puspatriani, Mutia Rahardjani, S Raijal, Helen Rees, Atika Rimainar, Charles W.M. Roberts, Anna Rocca, Sailendra Kumar Duwal Shrestha, Effua Usuf, C. Vidaillic, Fitria Wulandari, Amit Alexander, M. R. Amezaga, Charlotte Armah, Asma Asghar, Paula Aubrey, Kerry Barker-Williams, Amanda Barnard, John R. Bartholomew, Dawn Beaumont-Jewell, Simon Beddows, J. Beety, Chris Birch, Peter Boyle, Morwenna Brend, Matthew Brookes, Claire Callens, Danielle Campbell, Helen Campbell, Hugo Ten Cate, Emma S. Chambers, K Chapman, Antoinette B. Coe, Joanne Collins, Sarah Crawshaw, Sandeep R. Das, Anthony De Soyza, Erika Denton, Pamela Dicks, Mary Dolman, Kate Donaldson, Lucy Dowden, Shawn Dowling, Charles G. Drake, Hayley Duckles-Leech, Helen Duffy, Lee Gerdes, Kristen Gibbons, Lorena Almeida Gill, Kimberly Gilmour, Joanne Goodwin, James E. Graham, Christopher Green, Claire Hall, Alistair S. Hall, Kate Hampshire, Jane Hanson, T Harman, Helen Harper, Susan T.L. Harrison, James W. Hicks, Helen Hodgson, Michael Hough, Susan Jackson, Graham Johnson, Jodie Kirk, Nicholas R. Lemoine, Chris Levett, S Lock, Teresa Lockett, M Logan, Kaatje Lomme, Jing‐chao Luo, Nigel A.J. McMillan, Helen Membrey, Nhlanhla Mguni, Jane Minton, H Monaghan, Shawn N. Murphy, Natasha Muzengi, Madiha Naz, Ian Nickson, Miranda Odam, Udeme Ohia, Eleanor OKell, Antonio Oliver, Karen Pearson, Kirsty Pine, Richard J. Pleass, David A. Porter, Linda Porter, Alison Potter, Vanessa Poustie, Steven Pratt, Anna Price, Alicia Priest, Anthony Rodgers, C Rook, Pablo Ryan, S Sam, Phoebe Sharratt, James K. Sheffield, Justine Shenton, K Shirley, Timothy Skinner, Herbert B. Slade, Mihaela Sutu, Judy Taylor, E Thomas, Heather Tinkler, Alison Unsworth, R. Usher, William van’t Hoff, S E Walker, James Walters, E Walton, Jenny Warmington, Emma Wayman, Patricia Williams, John Williamson, Deborah A. Williamson, Fiona Yelnoorkar, Marian Knight, Kenneth Hodson, Sue Pavord, Catherine Williamson, Louise Bowman, Fei Chen, Robert W. Clarke, Michelle Goonasekara, William G. Herrington, P. G. Judge, S Ng, David Preiss, Christina Reith, Emily Sammons, Dandan Zhu, C Arkley, Paul Bowker, Johanna Bruce, Victoria Byrne-Watts, G Chapman, Grahame J. Coleman, Tom Denwood, J.D. Gray, David A Harrison, Nancy Mather, Heather Pinches, A.R. Rees, Stephanie Rees, Gail Turner, Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi,
BackgroundPaediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS-C) emerged in April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess the effect of intravenous immunoglobulin or corticosteroids compared with usual care on duration of hospital stay for children with PIMS-TS and to compare tocilizumab (anti-IL-6 receptor monoclonal antibody) or anakinra (anti-IL-1 receptor ...
Elsevier BV
Tom Abbott, T. Ahmad, M.K. Phull, A.J. Fowler, Russ Hewson, Bruce Biccard, Michelle S. Chew, Michael Gillies, Rupert M. Pearse, Rupert M. Pearse, Scott Beattie, Pierre-Alain Clavien, Nicolas Demartines, Lee A. Fleisher, Michael P. W. Grocott, J. B. Haddow, Andrea Bianchin, Peter Holt, Rui P. Moreno, Naomi Pritchard, Andrew Rhodes, Duminda N. Wijeysundera, M.G.F. Wilson, Tahania Ahmed, Kirsty Everingham, Russ Hewson, Marta Januszewska, Mandeep-Kaur Phull, Richard Halliwell, Mark Shulman, Paul S. Myles, Werner Schmid, M. Hiesmayr, Patrick Wouters, Stefan De Hert, Suzana M. Lobo, Xiangming Fang, Lars S. Rasmussen, Emmanuel Futier, Matthieu Biais, Aurélien Venara, K. Slim, Michael Sander, Despoina Koulenti, Kostoula Arvaniti, Matthew T.V. Chan, Atul Kulkarni, Susilo Chandra, Aida Rosita Tantri, Emad Geddoa, Muntadhar Abbas, Giorgio Della Rocca, Datin Sivasakthi, Marzida Mansor, Pastor Luna, R. Arthur Bouwman, Wolfgang Bühre, Vanessa Beavis, Doug Campbell, Timothy G. Short, Tunde Osinaike, Ricardo Matos, Ioana Grigoraş, М. Yu. Кirov, Д. Н. Проценко, Bruce Biccard, César Aldecoa, Michelle S. Chew, Christoph K. Hofer, Martin Hübner, James Ditai, Tamás Szakmány, Lee A. Fleisher, Marissa Ferguson, Michael MacMahon, Ritchie Cherian, Helen Currow, Kathirgamanathan Kanathiban, David Gillespie, Edward Pathmanathan, Katherine W. Phillips, J Reynolds, Joanne Rowley, J. Douglas, Ross Kerridge, Sameer Garg, Michael Bennett, Megha Jain, David Alcock, N Terblanche, R Cotter, Kate Leslie, Marcelle Stewart, Nicolette Zingerle, Antony Clyde, Oliver Hambidge, Adam Rehak, Sharon Cotterell, Wilson Binh Quan Huynh, Timothy M. McCulloch, Erez Ben‐Menachem, Thomas M. Egan, Jennifer R. Cope, Paul Fellinger, Markus Haisjackl, Simone Haselberger, Caroline Holaubek, Paul Lichtenegger, Florian Scherz, Franz Hoffer, Veronika Cakova, Andreas Eichwalder, Norbert Fischbach, R. Klug, Elisabeth Schneider, Martin Veselý, Reinhart Wickenhauser, Karl Gernot Grubmueller, Marion Leitgeb, Friedrich Lang, Nancy Toro, Marlene Bauer, Friedrich Laengle, Claudia Haberl, Thomas Mayrhofer, Christoph Trybus, Christian Buerkle, Karin Forstner, Reinhard Germann, Harald Rinoesl, Elke Schindler, Ernst Trampitsch, Gerhard Bogner, Daniel Dankl, Martin Duenser, G. Fritsch, Ilse Gradwohl-Matis, Andreas Hartmann, Thomas Hoelzenbein, Tarkan Jaeger, Franz Landauer, Gregor Lindl, Michael Lux, Johannes Steindl, Ottokar Stundner, Christian Szabo, Jawad Bidgoli, Hans Verdoodt, Patrice Forget, D. Ethan Kahn, Fernande Lois, Mona Momeni, Caroline Prégardien, Audrey Pospiech, Arnaud Steyaert, Laurent Veevaete, Dirk De Kegel, K. De Jongh, L. Foubert, Carine Smitz, M. Vercauteren, Jan Poelaert, Veerle Van Mossevelde, J Abeloos, Stefaan Bouchez, Marc Coppens, Luc De Baerdemaeker, Isabel Deblaere, Ann De Bruyne, Kristine Fonck, Björn Heyse, Tom Jacobs, Koen Lapage, Anneliese Moerman, Martine Neckebroek, Aliaksandra Parashchanka, Nathalie Roels, Nancy Van Den Eynde, Michaël Vandenheuvel, JurgenVan Limmen, Ann Vanluchene, Caroline Vanpeteghem, Piet Wyffels, Christel Huygens, Punitha Vandenbempt, Marc Van de Velde, Dimitri Dylst, Bruno Janssen, Evelien Schreurs, Fábia Berganton Aleixo, Keulle Candido, Hugo Dias Batista, Mário Guimarães, Jaqueline Guizeline, João Hoffmann, Francisco Ricardo Marques Lobo, Vinicius Carraro do Nascimento, Katia Nishiyama, Lucas Eduardo Pazetto, Daniela Souza, Rodrigo Rodrigues, Ana Maria Vilela dos Santos, Jaquelline Jardim, Luíz Marcelo Sá Malbouisson, João Silva, Paulo do Nascimento, Thalissa Hermínia Baio, Gabriel Isaac Pereira de Castro, Henri Roger Watanabe Oliveira, Cristina Prata Amêndola, Gutemberg Cardoso, Daniela Ortega, Ana Flavia Brotto, Mirella Cristine de Oliveira, Álvaro Réa-Neto, Fernando Augusto Lavezzo Dias, M. Travi, L. Zerman, Pedro Azambuja, Marcos Freitas Knibel, Antônio Sérgio Martins, William Almeida, Calim Neder Neto, Maria Ângela Tardelli, Eliana Bernadete Caser, Márcio Machado, Crisitiano Aguzzoli, Sérgio Vasconcellos Baldisserotto, Fernanda Beck Tabajara, Fernanda Bettega, La Hore Correa Rodrigues Júnior, Julia de Gasperi, Lais Faina, Marcos Farias Nolasco, Bruna Ferreira da Costa Fischer, Mariana Fosch de Campos Ferreira, Cristina Hartmann, Marta Kliemann, Gustavo Luis Hubert Ribeiro, Julia Merladete Fraga, Thiago Motta Netto, Laura Valduga Pozza, Paulo Rafael Wendling, Caroline Azevedo, Juliana Bueno Garcia, Marcel Rezende Lopes, Bernardo Maia, Paula Maselli, Ralph Melo, Weslley Mendes, Matheus Neves, Jacqueline Ney, Cláudio Piras, Christopher Applewhaite, Adrienne Carr, Lorraine Chow, Kaylene Duttchen, Julena Foglia, Michael W. Greene, Ashley Hinther, Kendra Houston, Thomas Jared McCormick, Jennifer Mikhayel, Sam Montasser, Alex Ragan, Andrew Suen, Adrianna Woolsey, Hai Yu, Duane J. Funk, Stephen Kowalski, Regina Legaspi, Heather McDonald, Faisal Sharaf Siddiqui, Jeremy Pridham, Bernadette Rowe, Sonia Sampson, Barton Thiessen, Geoff Zbitnew, André Bernard, Ronald B. George, Philip H. Jones, Rita Moor, Naveed Siddiqui, Alexandra Wolfer, Diem Tran, Denyse Winch, Gary Dobson, Thomas Jared McCormick, Osama Montasser, Richard Hall, Leyla Baghirzada, Gerard F. Curley, Si Dai, Gregory M. T. Hare, Esther Lee, Uma Shastri,
BackgroundThe surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool.MethodsProspective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital ...
Elsevier BV
Tom Abbott, Kathryn Greaves, A Patel, Tahania Ahmad, J. B. Haddow, Emmanuel Futier, Matthieu Biais, K. Slim, Rupert M. Pearse, Rupert M. Pearse, Scott Beattie, Pierre‐Alain Clavien, Nicolas Demartines, Lee A. Fleisher, Michael P. W. Grocott, J. B. Haddow, Andreas Hoeft, Peter Holt, Rui P. Moreno, Naomi Pritchard, Andrew Rhodes, Duminda N. Wijeysundera, M.G.F. Wilson, Tahania Ahmed, Kirsty Everingham, Russ Hewson, Marta Januszewska, Rupert M. Pearse, Mandeep-Kaur Phull, Richard Halliwell, Mark Shulman, Paul S. Myles, Werner Schmid, M. Hiesmayr, Patrick Wouters, Stefan De Hert, Suzana M. Lobo, Scott Beattie, Duminda N. Wijeysundera, Xiangming Fang, Lars S. Rasmussen, Emmanuel Futier, Matthieu Biais, Aurélien Venara, K. Slim, Michael Sander, Despoina Koulenti, Kostoula Arvaniti, Matthew T.V. Chan, Atul P Kulkarni, Susilo Chandra, Aida Rosita Tantri, Emad Geddoa, Muntadhar Abbas, Giorgio Della Rocca, Datin Sivasakthi, Marzida Mansor, Pastor Luna, R. Arthur Bouwman, Wolfgang Bühre, Vanessa Beavis, Douglas Campbell, Timothy G. Short, Tunde Osinaike, Ricardo Matos, Ioana Grigoraş, М. Yu. Кirov, Д. Н. Проценко, Bruce Biccard, César Aldecoa, Michelle S. Chew, Christoph K. Hofer, Martin Hübner, James Ditai, Tamás Szakmány, Lee A. Fleisher, Marissa Ferguson, Michael MacMahon, Mark Shulman, Ritchie Cherian, Helen Currow, Kathirgamanathan Kanathiban, David Gillespie, Edward Pathmanathan, Katherine W. Phillips, J Reynolds, Joanne Rowley, J. Douglas, Ross Kerridge, Helen Currow, Sameer Garg, Michael Bennett, Megha Jain, David Alcock, N Terblanche, R Cotter, Kate Leslie, Marcelle Stewart, Nicolette Zingerle, Antony Clyde, Oliver Hambidge, Adam Rehak, Sharon Cotterell, Wilson Binh Quan Huynh, Timothy M. McCulloch, Erez Ben‐Menachem, Thomas M. Egan, Jennifer R. Cope, Richard Halliwell, Paul Fellinger, Simone Haselberger, Caroline Holaubek, Paul Lichtenegger, Florian Scherz, Werner Schmid, Franz Hoffer, Veronika Cakova, Andreas Eichwalder, Norbert Fischbach, R. Klug, Elisabeth Schneider, Martin Veselý, Reinhart Wickenhauser, Karl Gernot Grubmueller, Marion Leitgeb, Friedrich Lang, Nancy Toro, Marlene Bauer, Friedrich Laengle, Thomas Mayrhofer, Christian Buerkle, Karin Forstner, Reinhard Germann, Harald Rinoesl, Elke Schindler, Ernst Trampitsch, G. Fritsch, Christian Szabo, Jawad Bidgoli, Hans Verdoodt, Patrice Forget, D. Ethan Kahn, Fernande Lois, Mona Momeni, Caroline Prégardien, Audrey Pospiech, Arnaud Steyaert, Laurent Veevaete, Dirk De Kegel, K. De Jongh, L. Foubert, Carine Smitz, M. Vercauteren, Jan Poelaert, Veerle Van Mossevelde, J Abeloos, Stefaan Bouchez, Marc Coppens, Luc De Baerdemaeker, Isabel Deblaere, Ann De Bruyne, Stefan De Hert, Kristine Fonck, Björn Heyse, Tom Jacobs, Koen Lapage, Anneliese Moerman, Martine Neckebroek, Aliaksandra Parashchanka, Nathalie Roels, Nancy Van Den Eynde, Michaël Vandenheuvel, Jurgen Van Limmen, Ann Vanluchene, Caroline Vanpeteghem, Patrick Wouters, Piet Wyffels, Christel Huygens, Punitha Vandenbempt, Marc Van de Velde, Dimitri Dylst, Bruno Janssen, Evelien Schreurs, Fábia Berganton Aleixo, Keulle Candido, Hugo Dias Batista, Mário Guimarães, Jaqueline Guizeline, João Hoffmann, Suzana M. Lobo, Francisco Ricardo Marques Lobo, Vinicius Carraro do Nascimento, Katia Nishiyama, Lucas Eduardo Pazetto, Daniela Souza, Rodrigo Rodrigues, Ana Maria Vilela dos Santos, Jaquelline Jardim, João Silva, Paulo do Nascimento, Thalissa Hermínia Baio, Gabriel Isaac Pereira de Castro, Henri Roger Watanabe Oliveira, Cristina Prata Amêndola, Gutemberg Cardoso, Daniela Ortega, Ana Flavia Brotto, Mirella Cristine de Oliveira, Álvaro Réa-Neto, Fernando Augusto Lavezzo Dias, Pedro Azambuja, Marcos Freitas Knibel, Antônio Sérgio Martins, William Almeida, Calim Neder Neto, Maria Ângela Tardelli, Eliana Bernadete Caser, Márcio Machado, Crisitiano Aguzzoli, Sérgio Vasconcellos Baldisserotto, Fernanda Beck Tabajara, Fernanda Bettega, La Hore Correa Rodrigues Júnior, Julia de Gasperi, Lais Faina, Marcos Farias Nolasco, Bruna Ferreira Costa Fischer, Mariana Fosch Campos Ferreira, Cristina Hartmann, Marta Kliemann, Gustavo Luis Hubert Ribeiro, Julia Merladete Fraga, Thiago Motta Netto, Laura Valduga Pozza, Paulo Rafael Wendling, Caroline Azevedo, Juliana Bueno Garcia, Marcel Rezende Lopes, Bernardo Maia, Paula Maselli, Ralph Melo, Weslley Mendes, Matheus Neves, Jacqueline Ney, Cláudio Piras, Christopher Applewhaite, Adrienne Carr, Lorraine Chow, Kaylene Duttchen, Julena Foglia, Michael W. Greene, Ashley Hinther, Kendra Houston, Thomas Jared McCormick, Jennifer Mikhayel, Sam Montasser, Alex Ragan, Andrew Suen, Adrianna Woolsey, Hai Yu, Duane J. Funk, Stephen Kowalski, Regina Legaspi, Heather McDonald, Faisal Sharaf Siddiqui, Jeremy Pridham, Bernadette Rowe, Sonia Sampson, Barton Thiessen, Geoff Zbitnew, André Bernard, Ronald B. George, Philip H. Jones, Rita Moor, Naveed Siddiqui, Alexandra Wolfer, Diem Tran, Denyse Winch, Gary Dobson, Ashley Hinther, Thomas Jared McCormick, Osama Montasser, Andrew Suen, Adrianna Woolsey, André Bernard, Ronald B. George, Richard Hall, André Bernard, Ronald B. George, Richard Hall, Christopher Applewhaite, Leyla Baghirzada, Thomas Jared McCormick, Andrew Suen, Si Dai, Gregory M. T. Hare,
The Clavien-Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien-Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational ...
Oxford University Press
Obbina Abani, Ali Abbas, Fatima Abbas, Joshua Abbas, Kasim Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Alison Abbott, Nabeel Abdallah, Ammar Abdelaziz, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, A Abdul, Basir Abdul, Siddiqui Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Lynn Abel, Katrina Abernethy, Movin Abeywickrema, C Abhinaya, Affyarsyah Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, C Aboah, Heba Aboelela, Hani Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, Mona Abouzaid, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, J. Abrams, Rebecca Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yousuf Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Faustina Acheampong, Prince Acheampong, Sarah Acheampong, Janet Acheson, S Achieng, Andrés Acosta, Rebecca Acquah, Catherine Acton, Jacqueline Adabie-Ankrah, Paul Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Marta Adamczyk, Carol Adams, Charlotte Adams, Daniel Adams, Kate Adams, Laura Adams, Nikkita Adams, Richard Adams, Tim Adams, L Adamu-Ikeme, Krishma Adatia, Kirsty Adcock, L Addai-Boampong, Afua Addo, Oluwatobi Adeagbo, Ade Adebiyi, Ogunlana Adedeji, Yewande Adegeye, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Femi W Adeoye, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Adedamola Adeyanju, Joyce Adeyemi, Tenifayo Adeyemo, Binay Adhikari, Shanti A Adhikari, Rina Adhikary, Adhikarla Aditya, P Adjepong, Gabrielle Adkins, Adnan Adnan, Marguerite Adriaanse, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Iqbal Afridi, P Afrim, Felicia Akua Afriyie, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, L A Aguilar Jimenez, Jacqueline Afrakomah Agyekum, K Agyen, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Afshan Ahmed, Ashar Ahmed, Asim Ahmed, Basheer A R Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Hanad Ahmed, Irshad Ahmed, Khaled Ahmed, Khalil Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rawya Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sana Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Bilal A Mohamud, Sana Ahmed, Sana Ahmer, A Ahonia, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, B Akinbiyi, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Mohammad Akram, Olugbenro Aktinade, U Akudi, Ahmad S A R Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Adegoke Alabi, Narendra Aladangady, Mohamed Alafifi, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Albertus Albertus, Lorraine Albon, Angela Alcala, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ram Maya Ale, Ana Alegria, Alison Alexander, Courtney Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, Rafil Alhameed, Mohammed Al-Hayali, Shams Al‐Hity, Ali Ali, Amanda Ali, Ali Asad, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohamed M. Ali, Mohammad Ali, Muhammad Ali, Nayab Ali, Oudai Ali, Ramla Ali, Sakina Ali, Syed Ahsan Ali, E Aliberti, J Alin, Abid Alina, A Alipustain, A Bachti, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, A. Alkhudhayri, Moutaz Alkhusheh, Fiona Allan, Nataliya Allan, Alison Allanson, Robert Allcock, Eireann Allen, Jade Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Tania Allen, A Alli, Kathryn Allison, Bethan Allman, Helen K Allsop, Lynne Allsop, David Allsup, Amal Almahroos, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Fadia Alsheikh, Bashar Al‐Sheklly, Sara Altaf, Amanda Alty, Mary Alvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Robert Ambrogetti, Chris Ambrose, Amir Ameen, A Amelia Ganefianty, Katharine Ames, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Badshah Amit, Amjad Amjad, Neelma Amjad, J Amoah-Dankwa, Victoria Amosun, Muhammad Amsal,
BackgroundLow-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support (non-invasive mechanical ventilation, invasive mechanical ventilation, or extracorporeal membrane oxygenation). We evaluated the use of a higher dose of corticosteroids in this patient group.MethodsThis randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing multiple possible treatments in patients hospitalised ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Joshua Abbas, Kasim Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Alison Abbott, Nabeel Abdallah, Ammar Abdelaziz, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, A Abdul, Basir Abdul, Siddiqui Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Lynn Abel, Katrina Abernethy, Movin Abeywickrema, C Abhinaya, Affyarsyah Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, Heba Aboelela, Hani Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, Mona Abouzaid, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Rebecca Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yousuf Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Prince Acheampong, Sarah Acheampong, Janet Acheson, S Achieng, Andrés Acosta, Rebecca Acquah, Catherine Acton, Jacqueline Adabie-Ankrah, Paul Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Marta Adamczyk, Carol Adams, Charlotte Adams, Daniel Adams, Kate Adams, Laura Adams, Nikkita Adams, Richard Adams, Tim Adams, L Adamu-Ikeme, Krishma Adatia, Kirsty Adcock, Afua Addo, Oluwatobi Adeagbo, Ade Adebiyi, Ogunlana Adedeji, Yewande Adegeye, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Femi W Adeoye, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Adedamola Adeyanju, Joyce Adeyemi, Tenifayo Adeyemo, Binay Adhikari, Rina Adhikary, Adhikarla Aditya, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, L A Aguilar Jimenez, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, M. Ridwan Said Ahmad, Syed A. Ahmad, Afshan Ahmed, Ashar Ahmed, Asim Ahmed, Basheer A R Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Hanad Ahmed, Irshad Ahmed, Khaled Ahmed, Khalil Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rawya Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sana Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Bilal A Mohamud, Sana Ahmed, Sana Ahmer, A Ahonia, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, B Akinbiyi, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Mohammad Akram, Olugbenro Aktinade, U Akudi, Ahmad S A R Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Adegoke Alabi, Narendra Aladangady, Mohamed Alafifi, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Angela Alcala, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ram Maya Ale, Ana Alegria, Alison Alexander, Courtney Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, Rafil Alhameed, Mohammed Al-Hayali, Shams Al‐Hity, Ali Ali, Amanda Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohamed M. Ali, Mohammad Ali, Muhammad Ali, Nayab Ali, Oudai Ali, Ramla Ali, Sakina Ali, Irfan Syed, E Aliberti, J Alin, Abid Alina, A Alipustain, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, A. Alkhudhayri, Moutaz Alkhusheh, Fiona Allan, Nataliya Allan, Alison Allanson, Robert Allcock, Eireann Allen, Jade Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Tania Allen, A Alli, Kathryn Allison, Bethan Allman, Helen K Allsop, Lynne Allsop, David Allsup, Amal Almahroos, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Fadia Alsheikh, Bashar Al‐Sheklly, Sara Altaf, Amanda Alty, Mary Alvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Katharine Ames, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Badshah Amit, Amjad Amjad, Neelma Amjad, Victoria Amosun, Muhammad Amsal, Khaled Amsha, Noelia Martín, Pugh Amy, A Anada, Atul Anand, Samantha Anandappa, Satya D Anantapatnaikuni, Ellen Anderson, Julie Anderson, Laura Anderson, Marina Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson,
BackgroundWe aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, for the treatment of patients admitted to hospital with COVID-19.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised with COVID-19 in the UK. Eligible and consenting patients were randomly allocated (1:1) to either usual standard of care alone (usual care group) or usual care plus ...
Elsevier BV
Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi, H Abbass, Anne L. Abbott, Nadine Abdallah, Ashraf Omar Abdelaziz, M Abdelfattah, Bushra Abdelqader, A Abdul, Basir Abdul, S Abdul, Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Mohammed, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Laurent Abel, Kathy Abernethy, Movin Abeywickrema, C Abhinaya, Ahmad Farid Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, C Aboah, Heba Aboelela, H Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, M. Abouzaid, Mathew Abraham, Tizzy Abraham, A. Abraheem, J. Abrams, Richard Abrams, HJ Abu, Ahmad Abu-Arafeh, SM Abubacker, Akata Abung, Yousef Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Faustina Acheampong, Paul Acheampong, Sarah Acheampong, James Acheson, S Achieng, Andrés Acosta, R Acquah, Cindy Acton, Jacqueline Adabie-Ankrah, Pauline Adair, AS Adam, Fiona Adam, Matthew Adam, Huzaifa Adamali, M Adamczyk, Christopher Adams, David H. Adams, Katie Adams, Lisa C. Adams, Nicholas M. Adams, Richard Adams, Tempestt Adams, L Adamu-Ikeme, Krishma Adatia, Kim G. Adcock, L Addai-Boampong, A. Addo, Oluwafemi Adeagbo, Adewole Adebiyi, O. S. Adedeji, Yewande Adegeye, K Adegoke, Vicki Adell, Sherna Adenwalla, FW Adeoye, OA Adesemoye, EO Adewunmi, A Adeyanju, Joyce Adeyemi, Titilope A. Adeyemo, Bidur Adhikari, SA Adhikari, R Adhikary, A. Aditya, P Adjepong, Gabrielle Adkins, Ahmad Adnan, M Adriaanse, J. Aeron-Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, P Afrim, FA Afriyie, ZA Aftab, Agnes Awuah, Mudit Agarwal, PN Agasiya, Rachel Agbeko, C Agbo, Sunil Aggarwal, A Aghababaie, L A Aguilar Jimenez, JA Agyekum, K Agyen, EK Ahadome, S Ahamed Sadiq, MH Ahammed Nazeer, Ahmad Mukhtar, Saad Ahmad, A. Ahmed, BAR Ahmed, Bilal Ahmed, Farhan Ahmed, Helal Uddin Ahmed, Irshad Ahmed, Kawsar Ahmed, L Ahmed, Muhammad S. Ahmed, MC Ahmed, MS Ahmed, Nausheen Ahmed, Nausheen Ahmed, Osama Ahmed, RA Ahmed, Rizwan Ahmed, Rizwan Ahmed, Sanam Ahmed, SG Ahmed, SH Ahmed, R Ahmed Ali, Bilal A Mohamud, Sanam Ahmed, Sana Ahmer, A Ahonia, Clement Aidoo, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, L Aitken, B Ajay, Abdulakeem Ajibode, Ahdi Noomen Ajmi, Nahid Akhtar, Suha Akili, B Akinbiyi, O Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Muhammad Akram, Olugbenro Aktinade, U Akudi, ASAR Al Aaraj, Ali Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, A Alabi, Narendra Aladangady, Mahmoud Alafifi, AHM Khurshid Alam, Md. Samrat Alam, A Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, A. Albertus, Lorraine Albon, Antonio Luna, Gemma Alcorn, Stephen Alcorn, Andrés Gómez-Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, N. Aldridge, RM Ale, Ana Alegria, Amit Alexander, Craig J. Alexander, John H. Alexander, PDG Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, R Alhameed, M Al-Hayali, Shams Al‐Hity, Ala Ali, FR Ali, Johar Ali, Mohammad Ali, MS Ali, Nayab Ali, Omar Hasan Ali, R Ali, Syed Ahsan Ali, E Aliberti, J Alin, Abid Alina, A Alipustain, Bachti Alisjahbana, Fine Aliyuda, Kaveh Alizadeh, Maithem Al-Jibury, S Al-Juboori, Mohammad Ali, A. Alkhudhayri, Moutaz Alkhusheh, Frank N. Allan, Nicholas P. Allan, Alison Allanson, Robert Allcock, Emma Allen, Jason W. Allen, Keeley Allen, Louise Allen, Pamela B. Allen, R Allen, Stephen Allen, Tammy D. Allen, A Alli, Kelly C. Allison, Brent E. Allman, HK Allsop, Lynne Allsop, David Allsup, AFT Almahroos, Hassan Al-Moasseb, M Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Z Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, F Alsheikh, Bashar Al‐Sheklly, Sana Altaf, A Alty, Míriam J. Álvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, N Amar, S Ambalavanan, Robert Ambrogetti, Christopher S. Ambrose, A Ameen, A Amelia Ganefianty, Katharine Ames, M. R. Amezaga, A Amin, A Amin, Kawa Amin, S Amin, Tarek Tawfik Amin, B Amit, Awais Amjad, Nasser Mohammad Amjad, J Amoah-Dankwa, Amos Amoako-Adusei, Victoria Amosun, M Amsal, Khaled Amsha, John Amuasi, Noelia Martín, Pugh Amy, A Anada, Atul Anand, Samantha Anandappa, SD Anantapatnaikuni, NKN Andari, Élizabeth Anderson, Jennifer Anderson,
BackgroundEmpagliflozin has been proposed as a treatment for COVID-19 on the basis of its anti-inflammatory, metabolic, and haemodynamic effects. The RECOVERY trial aimed to assess its safety and efficacy in patients admitted to hospital with COVID-19.MethodsIn the randomised, controlled, open-label RECOVERY trial, several possible treatments are compared with usual care in patients hospitalised with COVID-19. In this analysis, we assess eligible and consenting adults who were randomly allocated ...
Elsevier BV
Larry Mansouri, Lesley‐Ann Sutton, Viktor Ljungström, Sina Bondza, Linda Arngården, Sujata Bhoi, Jimmy Larsson, Diego Cortese, Antonia Kalushkova, Karla Plevová, Emma Young, Rebeqa Gunnarsson, Elin Falk-Sörqvist, Peter Lönn, Alice F. Muggen, Xiao‐Jie Yan, Birgitta Sander, Gunilla Enblad, Karin E. Smedby, Gunnar Juliusson, Chrysoula Belessi, Johan Rung, Nicholas Chiorazzi, Jonathan C. Strefford, Anton W. Langerak, Šárka Posp̂íšilová, Frédéric Davi, Mats Hellström, Helena Jernberg‐Wiklund, Paolo Ghia, Ola Söderberg, Κώστας Σταματόπουλος, Mats B. Nilsson, Richard Rosenquist,
NF-κB is constitutively activated in chronic lymphocytic leukemia (CLL); however, the implicated molecular mechanisms remain largely unknown. Thus, we performed targeted deep sequencing of 18 core complex genes within the NF-κB pathway in a discovery and validation CLL cohort totaling 315 cases. The most frequently mutated gene was NFKBIE (21/315 cases; 7%), which encodes IκBε, a negative regulator of NF-κB in normal B cells. Strikingly, 13 of these cases carried an identical 4-bp frameshift deletion, ...
Tópico(s): Galectins and Cancer Biology
2015 - Rockefeller University Press | The Journal of Experimental Medicine
Marian Rewers, Daniel Agardh, Suzanne Bennett Johnson, Ezio Bonifacio, Helena Elding Larsson, Patricia Gesualdo, William Hagopian, Michael J. Haller, Heikki Hyöty, Randi K. Johnson, Richard McIndoe, Eoin McKinney, Jessica Melin, Åke Lernmark, Richard E. Lloyd, Kristian Lynch, Jill M. Norris, Stephen S. Rich, Roswith Roth, Desmond Schatz, Jorma Toppari, Eric W. Triplett, Kendra Vehik, Suvi Μ. Virtanen, Anette‐Gabriele Ziegler, Beena Akolkar, Jeffrey P. Krischer, Marian Rewers, Kimberly Bautista, Judith Baxter, Daniel Felipe-Morales, Brigitte I. Frohnert, Marisa Stahl, Patricia Gesualdo, Michelle Hoffman, Randi K. Johnson, Rachel Karban, Edwin Liu, Jill Norris, Holly O’Donnell, Andrea K. Steck, Kathleen Waugh, Jorma Toppari, Olli Simell, Annika Adamsson, Suvi Ahonen, Iris Erlund, Sirpa Anttila, Leena Hakola, Sanni Heikura, Heikki Hyöty, Jorma Ilonen, Saori Itoshima, Sanna Jokipuu, Taru Karjalainen, Leena Eklund Karlsson, Pieta Kemppainen, Jukka Kero, Marika Korpela, Jaakko J. Koskenniemi, Miia Kähönen, Mikael Knip, Minna-Liisa Koivikko, Katja Kokkonen, Merja Koskinen, Mirva Koreasalo, Kalle Kurppa, Salla Kuusela, Jarita Kytölä, Jutta E. Laiho, Tiina Latva-aho, Siiri Leisku, Laura Leppänen, Katri Lindfors, Maria Lönnrot, Elina Mäntymäki, Markus Mattila, Maija E. Miettinen, Teija Mykkänen, Tiina Niininen, Sari Niinistö, Noora Nurminen, Sami Oikarinen, Hanna-Leena Oinas, Paula Ollikainen, Zhian Othmani, Sirpa Pohjola, Jenna Rautanen, M. F. Rein, Minna Romo, Juulia Rönkä, Nelli Rönkä, Noora Ruotsalainen, Satu Simell, Päivi Tossavainen, Mari Vähä-Mäkilä, Eeva Varjonen, Riitta Veijola, Irene Viinikangas, Suvi Μ. Virtanen, Richard McIndoe, Desmond Schatz, Diane Hopkins, Michael Haller, Melissa Gardiner, Ashok Sharma, Laura M. Jacobsen, Percy Gordon, Jennifer Hosford, Anette‐Gabriele Ziegler, Ezio Bonifacio, Cigdem Sanverdi, Anja Heublein, Sandra Hummel, Annette Knopff, Melanie Köger, Sibylle Koletzko, Claudia Ramminger, Roswith Roth, Jennifer Schmidt, Marlon Scholz, Joanna Stock, Katharina Warncke, Lothar Müller, Christiane Winkler, Åke Lernmark, Daniel Agardh, Carin Andrén Aronsson, Rasmus Bennet, Corrado Cilio, Susanne Dahlberg, Malin Goldman Tsubarah, Emelie Ericson-Hallström, Lina Fransson, Emina Halilovic, Susanne Hyberg, Berglind Jónsdóttir, Naghmeh Karimi, Helena Elding Larsson, Markus Lundgren, Jessica Melin, Kobra Rahmati, Anita Ramelius, Falastin Salami, Anette Sjöberg, Evelyn Tekum Amboh, Carina Törn, Terese Wiktorsson, Eva Andersson, Miia Turpeinen, Rawya Antar, Maria Ask, Jenny Bremer, Sören Svensson, Ulla-Marie Carlsson, Magdalena Delikat Kulinski, Annika Fors, Ulla Fält, Thomas Gard, Joanna Gerardsson, Monika Hansen, Anna Hansson, Carina Hansson, Gertie Hansson, Elin M. Hård af Segerstad, Hanna Jisser, Fredrik Johansen, Linda Jönsson, Silvija Jović, Sigrid Lenrick Forss, Barbro Lernmark, Marielle Lindström, Maria Markan, Theodosia Massadakis, Marlena Maziarz, Zeliha Mestan, Maria Månsson Martinez, Caroline Nilsson, Emma Nilsson, Yohanna Nordh, Karin Ottosson, Sara Rang, Anna Rosenquist, Monika Sedig Järvirova, Sara Sibthorpe, Birgitta Janerot-Sjöberg, Ulrika Swartling, Erika Trulsson, Ulrika Ulvenhag, Anne Wallin, I. Wigheden, Åsa Wimar, Sofie Åberg, William Hagopian, Michael Killian, Claire Cowen Crouch, Jennifer Skidmore, Ben Kim, Cody McCall, Arlene Meyer, Jared Radtke, Shreya Roy, Dorothy Becker, Margaret Franciscus, MaryEllen Dalmagro-Elias Smith, Ashi Daftary, Mary Beth Klein, Chrystal Yates, Jeffrey P. Krischer, Rajesh Adusumali, Sarah Austin-Gonzalez, Maryouri Avendano, Sandra Baethke, Brant Burkhardt, Martha Butterworth, Nicholas Cadigan, Joanna Clasen, Kevin Counts, Laura Gandolfo, Jennifer Garmeson, Veena Gowda, Shu Liu, Xiang Liu, Kristian Lynch, Jamie Malloy, Lazarus Mramba, Cristina McCarthy, Hemang Parikh, Cassandra Remedios, Chris Shaffer, Susan Smith, Noah Sulman, Roy Tamura, Dena Tewey, Henri Thuma, Michael J. Toth, Ulla Uusitalo, Kendra Vehik, Ponni Vijayakandipan, Melissa Wroble, Jimin Yang, Kenneth C. Young, Michael Abbondondolo, Lori Ballard, Rasheedah Brown, David Cuthbertson, Stephen Dankyi, Christopher Eberhard, Steven Fiske, David Hadley, Kathleen Heyman, Belinda Hsiao, Christina Karges, Francisco Perez Laras, Hye Seung Lee, Qian Li, Colleen Maguire, Wendy McLeod, Aubrie Merrell, Steven Meulemans, José L. Moreno, Ryan Quigley, Laura Smith, Liping Yu, Dongmei Miao, Kathleen M. Gillespie, Kyla Chandler, Olivia Pearce, Sarah J. Stollery, Elinor Balch, Hanah Batholomew, Zahra Hashmi, Elisabeth Aardal Eriksson, Inger Lundgren, E Karlsson, Dzeneta Neszirevic Dernroth, Michael Kalnoski, Chao-Nan Ting, Iris Erlund, Terhi Vihervaara, Petra Arohonka, Inga Liukko, Linda Patrikainen, Outi Ruotsalainen, Tiina Keippila, Stephen S. Rich, Wei‐Min Chen, Suna Önengüt-Gümüşcü, Emily Farber, Rebecca Roche Pickin, Jonathan M. Davis, Jordan P. Davis, Dan Gallo, Jessica Bonnie, Paul Campolieto, Randie R. Little,
American Diabetes Association
Henrik Stranneheim, Kristina Lagerstedt‐Robinson, Måns Magnusson, Malin Kvarnung, Daniel Nilsson, Nicole Lesko, Martin Engvall, Britt‐Marie Anderlid, Henrik Arnell, Carolina Backman Johansson, Michela Barbaro, Erik Björck, Helene Bruhn, Jesper Eisfeldt, Christoph Freyer, Giedré Grigelioniené, Peter Gustavsson, Anna Hammarsjö, Maritta Hellström-Pigg, Erik Iwarsson, Anders Jemt, Mikael Laaksonen, Sara Lind Enoksson, Helena Malmgren, K Naess, Magnus Nordenskjöld, Mikael Oscarson, Maria Pettersson, Chiara Rasi, Adam Rosenbaum, Ellika Sahlin, Eliane Sardh, Tommy Stödberg, Bianca Tesi, Emma Tham, Håkan Thonberg, Virpi Töhönen, Ulrika von Döbeln, Daphne Vassiliou, Sofie Vonlanthen, Ann–Charlotte Wikström, Josephine Wincent, Ola Winqvist, Anna Wredenberg, Sofia Ygberg, Rolf Zetterström, Per Marits, Maria Soller, Ann Nordgren, Valtteri Wirta, Anna Lindstrand, Anna Wedell,
Abstract Background We report the findings from 4437 individuals (3219 patients and 1218 relatives) who have been analyzed by whole genome sequencing (WGS) at the Genomic Medicine Center Karolinska-Rare Diseases (GMCK-RD) since mid-2015. GMCK-RD represents a long-term collaborative initiative between Karolinska University Hospital and Science for Life Laboratory to establish advanced, genomics-based diagnostics in the Stockholm healthcare setting. Methods Our analysis covers detection and interpretation ...
Tópico(s): Genomic variations and chromosomal abnormalities
2021 - BioMed Central | Genome Medicine
Natalie R. van Zuydam, Emma Ahlqvist, Niina Sandholm, Harshal Deshmukh, Nigel W. Rayner, Moustafa Abdalla, Claes Ladenvall, Daniel Ziemek, Eric B. Fauman, Neil R. Robertson, Paul McKeigue, Erkka Valo, Carol Forsblom, Valma Harjutsalo, Annalisa Perna, Erica Rurali, M. Loredana Marcovecchio, Robert P. Igo, Rany M. Salem, Norberto Perico, Maria Lajer, Annemari Käräjämäki, Minako Imamura, Michiaki Kubo, Atsushi Takahashi, Xueling Sim, Jianjun Liu, Rob M. van Dam, Guozhi Jiang, Claudia H.T. Tam, Andrea O. Y. Luk, Heung Man Lee, Cadmon K.P. Lim, Cheuk‐Chun Szeto, Wing Yee So, Juliana C.N. Chan, Su Fen Ang, Rajkumar Dorajoo, Ling Wang, Tan Si Hua Clara, Amy Jayne McKnight, Seamus Duffy, Marcus G. Pezzolesi, Michel Marre, Beata Gyorgy, Samy Hadjadj, Linda T. Hiraki, Tarunveer S. Ahluwalia, Peter Almgren, Christina‐Alexandra Schulz, Marju Orho‐Melander, Allan Linneberg, Cramer Christensen, Daniel R. Witte, Niels Grarup, Ivan Brandslund, Olle Melander, Andrew D. Paterson, David‐Alexandre Trégouët, Alexander P. Maxwell, Su Chi Lim, Ronald C.W., E. Shyong Tai, Shiro Maeda, Valeriya Lyssenko, Jaakko Tuomilehto, Andrzej S. Królewski, Stephen S. Rich, Joel N. Hirschhorn, José C. Florez, David B. Dunger, Oluf Pedersen, Torben Hansen, Peter Rossing, Giuseppe Remuzzi, M. Julia Brosnan, Nicholette D. Palmer, Per‐Henrik Groop, Helen M. Colhoun, Leif Groop, Mark I. McCarthy, Satu Koivula, T. Uggeldahl, Terje Forslund, A. Halonen, A. Koistinen, P. Koskiaho, M. Laukkanen, Juha Saltevo, Miia Tiihonen, M. Forsen, Helena Granlund, A.-C. Jönsson, B. Nyroos, Pentti Kinnunen, A. Orvola, Tapani Salonen, A. Vähänen, Kotka R. Paldanius, M Riihelä, L. Ryysy, Kemi H. Laukkanen, P. Nyländen, Anni Sademies, S. Anderson, Barbro Asplund, U. Byskata, P. Liedes, M. Kuusela, T. Virkkala, Anssi Nikkola, E. Ritola, Tapiola M. Niska, Harri Juhani Saarinen, Samaria E. Oukko-Ruponen, Tuula Virtanen, Viherlaakso A. Lyytinen, P H Kari, T. Simonen, Suutarila A. Kaprio, Jorma Kärkkäinen, B. Rantaeskola, Toolo P. Kääriäinen, J R Haaga, A.-L. Pietiläinen, Sanna Klemetti, T. Nyandoto, E. Rontu, S. Satuli-Autere, Korso R. Toivonen, H. Virtanen Lansimaki, Riitta Ahonen, M. Ivaska-Suomela, Anneli Jauhiainen, Martinlaakso M. Laine, T. Pellonpää, R. Puranen, Myyrmaki A. Airas, Juha Laakso, K. Rautavaara, Rekola M. Erola, E. Jatkola, Tikkurila R. Lönnblad, Anna Malm, Jyrki Mäkelä, E. Rautamo, P. Hentunen, J. Lagerstam, Maija Feodoroff, Daniel Gordin, Outi Heikkilä, Kustaa Hietala, J. Fagerudd, Minna A. Korolainen, L. Kyllönen, Janne Kytö, S. Lindh, Kim Pettersson-Fernholm, Milla Rosengård‐Bärlund, Amanda Sandelin, Lena M. Thorn, Jaana Tuomikangas, T. Vesisenaho, Johan Wadén, V. Sipilä, Forssa T. Kalliomäki, J. Koskelainen, R. Nikkanen, N. Savolainen, Hannu Sulonen, E. Valtonen, Leena Norvio, Anne Hämäläinen, E. Toivanen, Jamsa A. Parta, I. Pirttiniemi, S. Aranko, Satu Ervasti, Ronald C.W., Ari Kuusisto, T. Leppälä, Katriina Nikkilä, L. Pekkonen, K. Jokelainen, Kristiina Kananen, Matti Karjalainen, Pentti Kemppainen, A.-M. Mankinen, A. Reponen, M. Sankari, Pauli Suominen, Anu K. Lappalainen, Maarit Liimatainen, J. Santaholma, Ari Aimolahti, Elisa Huovinen, V. Ilkka, M. Y. Lehtimäki, E. Pälikkö-Kontinen, Antti Vanhanen, E. Koskinen, Timo Siitonen, Erja Huttunen, Risto Ikäheimo, Pauli Karhapää, Päivi Kekäläinen, M. Laakso, Timo A. Lakka, E Lampainen, Leena Moilanen, Sanna Tanskanen, Leo Niskanen, U. Tuovinen, Ilkka Vauhkonen, Erkki Voutilainen, Ronald C.W., Juliana C.N. Chan, Yü Huang, Hui Y. Lan, Si Lok, Brian Tomlinson, Stephen Kwok‐Wing Tsui, Weichuan Yu, Kevin Y.L. Yip, Ting‐Fung Chan, Xiaodan Fan, Wing Yee So, Cheuk‐Chun Szeto, Nelson L.S. Tang, Andrea O. Y. Luk, Xiao Yu Tian, Guozhi Jiang, Claudia H.T. Tam, Heung Man Lee, Cadmon K.P. Lim, Kei Hang Katie Chan, Fangying Xie, Alex C.W. Ng, Grace P.Y. Cheung, Ming Wai Yeung, Mai Shi, Fei Xie, Sen Zhang, Yu Pu, Meng Weng, Alexander P. Maxwell, Amy Jayne McKnight, David A. Savage, James D. Walker, Stephen Thomas, Giancarlo Viberti, A.J.M. Boulton, S. M. Marshall, Andrew Demaine, B. A. Millward, Steve Baín, Niina Sandholm, Carol Forsblom, Valma Harjutsalo, Ville‐Petteri Mäkinen, Aila J. Ahola, Emma H. Dahlström, Daniel Gordin, Outi Heikkilä, Kustaa Hietala, Janne Kytö, Markku Lehto, Raija Lithovius, Nicolae Mircea Panduru, Maija Parkkonen, Milla Rosengård‐Bärlund, Markku Saraheimo, Jenny Söderlund, Aino Soro‐Paavonen, Anna Syreeni, Lena M. Thorn, Nina Tolonen, Johan Wadén, Per‐Henrik Groop, Amy Jayne McKnight, Gareth J. McKay, Alexander P. Maxwell, Rany M. Salem, Tamara Isakova, Nicholette D. Palmer, Candace Guiducci, Andrew M. Taylor, Daniel B. Mirel, Winfred W. Williams, Joel N. Hirschhorn, José C. Florez, Eoin Brennan, Denise M. Sadlier, Finian Martin, Catherine Godson, Lynne Mayer,
Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to provide insights into the pathophysiological mechanisms responsible. We conducted a genome-wide association study (GWAS) of DKD in type 2 diabetes (T2D) using eight complementary dichotomous and quantitative DKD phenotypes: the principal dichotomous analysis involved 5,717 T2D subjects, 3,345 with DKD. Promising association signals were evaluated in up to 26,827 subjects ...
American Diabetes Association
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Kirsty Adcock, Jemaimah Addai, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Penny Agent, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, M. Ridwan Said Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Charlotte Alford, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizaedeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Ken Amenyah, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Marie Anne Ledingham, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Deborah Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain,
BackgroundIn this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation ( ...
Elsevier BV
Athanasios Kousathanas, Erola Pairo‐Castineira, Konrad Rawlik, A. Stuckey, Christopher A. Odhams, Susan Walker, Clark D Russell, Tomas Malinauskas, Yang Wu, Jonathan Millar, Xia Shen, Katherine S. Elliott, Fiona Griffiths, Wilna Oosthuyzen, Kirstie Morrice, Seán Keating, Bo Wang, Daniel R. Rhodes, Lucija Klarić, Marie Zechner, Nick Parkinson, Afshan Siddiq, Peter Goddard, Sally Donovan, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Tala Zainy, F. Maleady-Crowe, Linda Todd, Shahla Salehi, Julian C. Knight, Greg Elgar, G. C. Chan, Prabhu Arumugam, Christine Patch, Augusto Rendon, David Bentley, Clare Kingsley, Jack A. Kosmicki, Julie Horowitz, Aris Baras, Gonçalo R. Abecasis, Manuel A. R. Ferreira, Anne E. Justice, Tooraj Mirshahi, Matthew T. Oetjens, Daniel J. Rader, Marylyn D. Ritchie, Anurag Verma, Tom Fowler, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Paul Elliott, Timothy Walsh, Albert Tenesa, J. Kenneth Baillie, Colin B. Begg, Sara Clohisey, Charles Hinds, Peter Horby, Julian C. Knight, Lowell Ling, David M. Maslove, Daniel F. McAuley, Johnny Millar, Hugh Montgomery, Alistair Nichol, Peter Openshaw, Alexandre C. Pereira, Chris P. Ponting, Kathy Rowan, Malcolm G. Semple, Manu Shankar‐Hari, Charlotte Summers, Timothy Walsh, Latha Aravindan, Ruth Armstrong, Heather Biggs, Ceilia Boz, Adam Brown, Richard E. Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Angie Fawkes, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Andy Law, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Kirstie Morrice, Lee Murphy, Sheena Murphy, Mybaya Hellen, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Gill Arbane, Aneta Bociek, Sara Campos, Neus Grau, Tim Jones, Rosario Lim, Martina Marotti, Marlies Ostermann, Manu Shankar‐Hari, R. Chris Whitton, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew L. Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, David Collier, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, P. May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, S. M. Wood, Anne Zak, Olivier Zongo, Stephen Bonner, Keith Hugill, Jessica Jones, Steven Liggett, Evie Headlam, Nageswar Bandla, Minnie Gellamucho, Michelle Davies, C. C. Thompson, Marwa Abdelrazik, Dhanalakshmi Bakthavatsalam, Munzir Elhassan, Arunkumar Ganesan, Anne Haldeos, Jerónimo Moreno-Cuesta, Dharam Purohit, Rachel Vincent, Kugan Xavier, Rohit Kumar, Alasdair Frater, Malik Saleem, Emma Carter, Samuel Jenkins, Zoe Lamond, Alanna Wall, Jaime Fernandez-Roman, David Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, David Shaw, Alicia Waite, Victoria Waugh, Ingeborg Welters, Karen Williams, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Mark McPhail, Monalisa Nayak, Harriet Noble, Kevin O’Reilly, Evita Pappa, Rohit Saha, Sian Saha, John Smith, Abigail Knighton, David Antcliffe, Dorota Banach, Stephen J. Brett, Phoebe Coghlan, Ziortza Fernandez, Anthony Gordon, Roceld Rojo, Sonia Sousa Arias, Maie Templeton, Megan Meredith, Lucy Morris, Lucy Ryan, Amy Clark, Julia Sampson, Cecilia Peters, Martin Dent, Margaret Langley, Saima Ashraf, Shuying Wei, Angela Andrew, Archana Bashyal, Neil Davidson, Paula Hutton, Stuart McKechnie, Jean Wilson, David Baptista, Rebecca Crowe, Rita Fernandes, Rosaleen Herdman-Grant, Anna Joseph, Denise O’Connor, Meryem Allen, Adam Loveridge, India McKenley, Eriko Morino, Andrés Naranjo, Richard Simms, Kathryn Sollesta, Andrew Swain, Harish Venkatesh, Jacyntha Khera, Jonathan Fox, Gillian Andrew, J. Kenneth Baillie, Lucy Barclay, Marie Callaghan, Rachael Campbell, Sarah J. Clark, Dave Hope, Lucy Marshall, Corrienne McCulloch, Kate Briton, Jo Singleton, Sophie Birch, Lutece Brimfield, Zoe Daly, David Pogson, Steve Rose, Angela Nown,
Abstract Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care 1 or hospitalization 2–4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals ...
Nature Portfolio
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Kirsty Adcock, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Binay Adhikari, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Georgia Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Deborah Athorne,
BackgroundAspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients admitted to hospital with COVID-19.MethodsIn this randomised, controlled, open-label, platform trial, several possible treatments were compared with usual care in patients hospitalised with COVID-19. The trial took place at 177 hospitals in the UK, two hospitals in Indonesia, and two hospitals in Nepal. Eligible and consenting ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, D. Abdo, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Amina Abdulle, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Sara J. Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Lisa C. Adams, Richard Adams, Tim Adams, Kirsty Adcock, Jemaimah Addai, Ade Adebiyi, Ken Adegoke, Vicki Adell, Debo Ademokun, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Dominic Affron, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Penny Agent, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Humayun Ahmad, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Sophia Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Giulia Airoldi, Myriam Aissa, Lindianne Aitken, Bini Ajay, Francis Ajeneye, Abdulakeem Ajibode, Ayesha Ajmi, Tahir Akbar, Naim Akhtar, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olajide Akinwumiju, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Karina Al-Asadi, Kyriaki S. Alatzoglou, Manaf Al-Bayati, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Charlotte Alford, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Hoodo Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sabira Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Allameddine Allameddine, Fiona Allan, Rachel Allan, Alison Allanson, Robert Allcock, B. Allen, Eireann Allen, Jess Allen, Kerry Allen, Laura K. Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Balaal Alyas, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Kenneth Amenyah, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Mariam Ammoun, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Rekha Anand, Samantha Anandappa, Julie Anderson, Kevin L. Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Susan Andrews, Gregory Andrikopoulos, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, George Apostolides, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Emily Arbon, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Sylvia Armstrong‐Fisher, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold,
BackgroundMany patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from across the UK. ...
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