Andarini Diharmi, Dedi Fardiaz, Nuri Andarwulan, Endang Sri Heruwati,
... relatively higher than that of N usa P enida (25.81 ± 1.93%). The calcium content was ... than that of carrageenan from N usa P enida and S umenep. Likewise, upon cooling from 80 ... carrageenan from S umenep and N usa P enida. These results indicated that carrageenan from N usa P enida, S umenep, and T akalar were identified as ...
Tópico(s): Echinoderm biology and ecology
2017 - Wiley | Phycological Research
Stanley J. Robboy, Pacita Keh, Rita J. Nickerson, Enida K. Helmanis, Jaime Prat, Wanda M. Szyfelbein, Priscilla D. Taft, Ann B. Barnes, Robert E. Scully, William R. Welch,
Squamous cell abnormalities of the vagina and cervix were evaluated in 1424 women exposed to diethylstilbestrol (DES) in utero. The prevalence of dysplasia was 2.1% and the incidence 0.85/100 person-years of followup. The dysplastic epithelial changes were almost always mild in women with no prior history of dysplasia and was slightly more frequent in the cervix than the vagina. Severe dysplasia and carcinoma in situ (CIS) were encountered only in those subjects specifically referred because of those ...
Tópico(s): Toxic Organic Pollutants Impact
1978 - Lippincott Williams & Wilkins | Obstetrics and Gynecology
Paolo Belli, Melania Costantini, Enida Bufi, Andrea Magistrelli, Giuseppe La Torre, L. Bonomo,
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2009 - Springer Science+Business Media | La radiologia medica
Taku Ishizaki, Agnes Erickson, Enida Kuric, Mehrdad Shamloo, Ikuko Hara‐Nishimura, Ana R. Inácio, Tadeusz Wieloch, Karsten Ruscher,
Various proteases in the brain contribute to ischemic brain injury. We investigated the involvement of the asparaginyl endopeptidase legumain after experimental stroke. On the basis of gene array studies and in situ hybridizations, we observed an increase of legumain expression in the peri-infarct area of rats after transient occlusion of the middle cerebral artery (MCAO) for 120 mins with a maximum expression at 24 and 48 h. Immunohistochemical analyses revealed the expression of legumain in Iba1 + ...
Tópico(s): Signaling Pathways in Disease
2010 - SAGE Publishing | Journal of Cerebral Blood Flow & Metabolism
Pierluigi Rinaldi, Michela Giuliani, Paolo Belli, Melania Costantini, M. Romani, Daniela Distefano, Enida Bufi, Antonino Mulè, Stefano Magno, Riccardo Masetti, Lorenzo Bonomo,
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2010 - Elsevier BV | European Journal of Radiology
Melania Costantini, Paolo Belli, Pierluigi Rinaldi, Enida Bufi, G Giardina, Gianluca Franceschini, Gianluigi Petrone, L. Bonomo,
Aim To assess the utility of diffusion-weighted imaging in diagnosing and characterizing breast malignancy. Materials and methods From April 2006 to April 2009, all consecutive patients with breast cancer undergoing breast magnetic resonance imaging (MRI) and subsequent surgery in our hospital were enrolled in this study. MRI was performed using a 1.5T MRI unit using a dedicated, bilateral, four-channel breast coil. The MRI protocol included a diffusion sequence acquired using b values of 0 and 1000s/ ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2010 - Elsevier BV | Clinical Radiology
Pierluigi Rinaldi, Melania Costantini, Paolo Belli, Michela Giuliani, Enida Bufi, rita Fubelli, Daniela Distefano, M. Romani, L. Bonomo,
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2011 - Springer Science+Business Media | European Radiology
Paolo Belli, Melania Costantini, Carmine Ierardi, Enida Bufi, D Amato, Antonino Mulè, Luigia Nardone, Daniela Terribile, Lorenzo Bonomo,
The aim of this study was to investigate the role of diffusion imaging in the evaluation of response to neoadjuvant breast cancer treatment by correlating apparent diffusion coefficient (ADC) value changes with pathological response. From June 2007 to June 2009, all consecutive patients with histopathologically confirmed breast cancer undergoing neoadjuvant chemotherapy were enrolled. All patients underwent magnetic resonance imaging (MRI) (including diffusion sequence) before and after neoadjuvant ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2011 - Wiley | The Breast Journal
Karsten Ruscher, Enida Kuric, Tadeusz Wieloch,
Background and Purpose— Delayed treatment of patients with stroke with levodopa/benserazide contributes to enhanced functional recovery, but the mechanisms involved are poorly understood. The present study was designed to investigate if levodopa/benserazide treatment improves recovery of lost neurological function and contributes to tissue reorganization in the rat brain after stroke. Methods— Male Wistar rats were subjected to transient occlusion of the middle cerebral artery (120 minutes) and treated ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2011 - Lippincott Williams & Wilkins | Stroke
Melania Costantini, Paolo Belli, Daniela Distefano, Enida Bufi, Marialuisa Di Matteo, Pierluigi Rinaldi, Michela Giuliani, Gianluigi Petrone, Stefano Magno, Lorenzo Bonomo,
It has been ascertained that triple-negative (TN) breast cancer is characterized by an aggressive clinical course and a poor prognosis. The purpose of our study was to compare the magnetic resonance imaging (MRI) features of the 3 major different breast cancer subtypes (TN, luminal, and human epidermal growth factor receptor 2 [HER2]-overexpressing) and to suggest the criteria that might predict TN phenotype.From October 2007 to April 2011, we studied 77 patients with histologically confirmed TN breast ...
Tópico(s): MRI in cancer diagnosis
2012 - Elsevier BV | Clinical Breast Cancer
Melania Costantini, Antonio Cipriani, Paolo Belli, Enida Bufi, rita Fubelli, Giuseppe Visconti, Marzia Salgarello, L. Bonomo,
Aim To describe the radiological appearance of normal and pathological findings resulting from mammary autologous fat injections (lipofilling). Materials and methods Informed consent and institutional review board approval were obtained. From January 2008 to December 2010, all patients that had undergone breast lipofilling at our institution (Catholic University) were consecutively enrolled. The site and amount of autologous fat injections were known. Mammography, ultrasonography, and magnetic resonance ...
Tópico(s): Breast Implant and Reconstruction
2012 - Elsevier BV | Clinical Radiology
Karsten Ruscher, Ana R. Inácio, Kristian Valind, Arman Rowshan Ravan, Enida Kuric, Tadeusz Wieloch,
Activation of the sigma-1 receptor (Sig-1R) improves functional recovery in models of experimental stroke and is known to modulate microglia function. The present study was conducted to investigate if Sig-1R activation after experimental stroke affects mediators of the inflammatory response in the ischemic hemisphere. Male Wistar rats were subjected to transient occlusion of the middle cerebral artery (MCAO) and injected with the specific Sig-1R agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl) ...
Tópico(s): Neuropeptides and Animal Physiology
2012 - Public Library of Science | PLoS ONE
Abstract The activation of inflammatory cascades in the ischemic hemisphere impairs mechanisms of tissue reorganization with consequences for recovery of lost neurological function. Recruitment of T‐cell populations to the post‐ischemic brain occurs and represents a significant part of the inflammatory response. This study was conducted to investigate if treatment with levodopa, potentially acting as an immunomodulator, affects the T‐cell accumulation in the post‐ischemic brain. Male Sprague–Dawley ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2014 - Wiley | European Journal of Neuroscience
Paolo Belli, Melania Costantini, Enida Bufi, Giuseppe Giovanni Giardina, Pierluigi Rinaldi, Gianluca Franceschini, Lorenzo Bonomo,
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2014 - Springer Science+Business Media | La radiologia medica
Enida Gjoni, L. Brioschi, Alessandra Cinque, Nicolas Coant, M. Nurul Islam, Carl K.‐Y. Ng, Claudia Verderio, Chr̀istophe Magnan, Laura Riboni, Paola Viani, Hervé Le Stunff, Paola Giussani,
Accumulating evidence suggests that glucolipotoxicity, arising from the combined actions of elevated glucose and free fatty acid levels, acts as a key pathogenic component in type II diabetes, contributing to β-cell dysfunction and death. Endoplasmic reticulum (ER) stress is among the molecular pathways and regulators involved in these negative effects, and ceramide accumulation due to glucolipotoxicity can be associated with the induction of ER stress. Increased levels of ceramide in ER may be due ...
Tópico(s): Erythrocyte Function and Pathophysiology
2014 - Public Library of Science | PLoS ONE
Cerebral ischemia activates both the innate and the adaptive immune response, the latter being activated within days after the stroke onset and triggered by the recognition of foreign antigens. In this study we have investigated the phenotype of antigen presenting cells and the levels of associated major histocompatibility complex class II (MHC II) molecules in the postischemic brain after transient occlusion of the middle cerebral artery (tMCAO) followed by levodopa/benserazide treatment. Male Sprague ...
Tópico(s): Neuroscience and Neuropharmacology Research
2014 - BioMed Central | Journal of Neuroinflammation
Enida Bufi, Paolo Belli, Marialuisa Di Matteo, Daniela Terribile, Gianluca Franceschini, Luigia Nardone, Gianluigi Petrone, Lorenzo Bonomo,
The estimation of response to neoadjuvant chemotherapy (NAC) is useful in the surgical decision in breast cancer. We addressed the diagnostic reliability of conventional MRI, of diffusion weighted imaging (DWI) and of a merged criterion coupling morphological MRI and DWI. Diagnostic performance was analysed separately in different tumor subtypes, including HER2+ (human epidermal growth factor receptor 2)/HR+ (hormone receptor) (hybrid phenotype).Two-hundred and twenty-five patients underwent MRI before ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2014 - Elsevier BV | European Journal of Radiology
Enida Kuric, Tadeusz Wieloch, Karsten Ruscher,
Treatment with levodopa enhances functional recovery after experimental stroke but its mechanisms of action are elusive. Reactive astrocytes in the ischemic hemisphere are involved in mechanisms promoting recovery and also express dopamine 1 (D1) and dopamine 2 (D2) receptors. Here we investigated if the activation of astrocytic dopamine receptors (D1 and D2) regulates the expression of glial cell line-derived neurotrophic factor (GDNF) after combined in vitro hypoxia/aglycemia (H/A) and studied the ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2013 - Elsevier BV | Experimental Neurology
Le Xiao, Nicolas Michalski, Elin Kronander, Enida Gjoni, Christel Genoud, Graham Knott, Ralf Schneggenburger,
Tópico(s): Cancer-related molecular mechanisms research
2013 - Nature Portfolio | Nature Neuroscience
Karsten Ruscher, Enida Kuric, Yawei Liu, Helene Luise Walter, Shohreh Issazadeh‐Navikas, Elisabet Englund, Tadeusz Wieloch,
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing rats in an enriched environment (EE) dramatically improves recovery of lost neurologic functions after experimental stroke. We show here that rats housed in EE after stroke induced by permanent occlusion of the middle cerebral artery (pMCAO), showed attenuated levels of proinflammatory cytokines in the ischemic core and the surrounding peri-infarct area, including a significant ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2013 - SAGE Publishing | Journal of Cerebral Blood Flow & Metabolism
Enida Pulaj, Vasilika Kume, Amali Çipi,
One of the main questions that guide researches in management field is why some companies are different and obtain good performance compare to other companies. Nowadays, there has been a growing intensity of competition in all areas of business and this has resulted in greater attention to analyse competitive behaviour under different competitive strategies application and environmental dynamics and complexity. The purpose of this paper is to examine the relationship between competitive strategies ...
Tópico(s): Global Trade and Competitiveness
2015 - European Scientific Institute | European Scientific Journal ESJ
Ahmed Radwan, Kyle A. Bigney, Haily N. Buonomo, Michael W. Jarmak, Shannon M. Moats, Jaimie K. Ross, Enida Tatarevic, Mary Anne Tomko,
PURPOSE:To evaluate the extent of intra-subject difference in hamstring flexibility and its possible relationship to the severity of Low Back Pain (LBP). A secondary purpose was to evaluate the extent of intra-rater reliability using both electrogoniometer and conventional goniometer for measuring hamstring tightness. IMPORTANCE:Potential correlations between muscle impairments and LBP may lead to more effective treatments and prevention strategies. METHODS:Seventy two participants with mechanical ...
Tópico(s): Sports Performance and Training
2015 - IOS Press | Journal of Back and Musculoskeletal Rehabilitation
Melania Costantini, Paolo Belli, Enida Bufi, Anna Maria Asunis, Enrico Ferra, Grazia Bitti,
The purpose of this study was to investigate potential associations between invasive breast cancer sonographic (US) findings and histopathologic patterns and biomarkers.One hundred consecutive women with invasive breast cancer treated in the Breast Diagnostic Center of Brotzu Hospital in Cagliari, Italy, from January to October 2013, were retrospectively evaluated. Two experienced breast radiologists independently evaluated hard copies of US examinations performed during the US-guided biopsy procedure. ...
Tópico(s): Ultrasound Imaging and Elastography
2015 - Wiley | Journal of Clinical Ultrasound
Enida Bufi, Paolo Belli, Melania Costantini, Antonio Cipriani, Marialuisa Di Matteo, Angelo Bonatesta, Gianluca Franceschini, Daniela Terribile, Antonino Mulè, Luigia Nardone, Lorenzo Bonomo,
We evaluated the diagnostic performance of the baseline diffusion weighted imaging (DWI) and the apparent diffusion coefficient (ADC) in the prediction of a complete pathologic response (pCR) to neoadjuvant chemotherapy (NAC) in patients with breast cancer stratified according to the tumor phenotype.We retrospectively studied 225 patients with stage II, III, and IV breast cancer who had undergone contrast-enhanced magnetic resonance imaging (MRI) and DWI before and after NAC, followed by breast surgery. ...
Tópico(s): Breast Lesions and Carcinomas
2015 - Elsevier BV | Clinical Breast Cancer
Marcus Lundberg, Lars Krogvold, Enida Kuric, Knut Dahl‐Jørgensen, Oskar Skog,
A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate immunity, has been suggested as an important step in the inflammatory process in type 1 diabetes (T1D). The aim of this study was to examine whether interferon (IFN)-stimulated genes (ISGs) are overexpressed in human T1D islets affected with insulitis. By using laser capture microdissection and a quantitative PCR array, 23 of 84 examined ISGs were found to be overexpressed by at least fivefold in insulitic ...
Tópico(s): Immune Cell Function and Interaction
2016 - American Diabetes Association | Diabetes
Laura Rottner, Andreas Metzner, Feifan Ouyang, Christian‐Hendrik Heeger, Kentaro Hayashi, Thomas Fink, Christine Lemeš, Shibu Mathew, Tilman Maurer, Bruno Reißmann, Enida Rexha, Johannes Riedl, Ardan M. Saguner, Francesco Santoro, Karl‐Heinz Kück, Christian Sohns,
Point‐by‐Point versus Rapid Ultra‐High‐Resolution Electroanatomical Mapping in AF Introduction Three‐dimensional electroanatomical mapping (EAM) is an established tool facilitating catheter ablation. In this context, the novel Rhythmia system sets a new bar in fast high‐resolution mapping. The aim of this study was to directly compare point‐by‐point versus rapid ultra‐high‐resolution EAM in patients scheduled for ablation of atrial fibrillation (AF) with focus on procedural data, acute success, and ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2017 - Wiley | Journal of Cardiovascular Electrophysiology
Enida Kuric, Peter Seiron, Lars Krogvold, Bjørn Edwin, Trond Buanes, Kristian F. Hanssen, Oskar Skog, Knut Dahl‐Jørgensen, Olle Korsgren,
Tópico(s): Diabetes Management and Research
2017 - Elsevier BV | American Journal Of Pathology
Brice Bouhours, Enida Gjoni, Olexiy Kochubey, Ralf Schneggenburger,
Parvalbumin-expressing inhibitory neurons in the mammalian CNS are specialized for fast transmitter release at their output synapses. However, the Ca 2+ sensor(s) used by identified inhibitory synapses, including the output synapses of parvalbumin-expressing inhibitory neurons, have only recently started to be addressed. Here, we investigated the roles of Syt1 and Syt2 at two types of fast-releasing inhibitory connections in the mammalian CNS: the medial nucleus of the trapezoid body to lateral ...
Tópico(s): Lipid Membrane Structure and Behavior
2017 - Society for Neuroscience | Journal of Neuroscience
Laura Rottner, Thomas Fink, Christian‐Hendrik Heeger, Michael Schlüter, Britta Goldmann, Christine Lemeš, Tilman Maurer, Bruno Reißmann, Enida Rexha, Johannes Riedl, Francesco Santoro, Peter Wohlmuth, Shibu Mathew, Christian Sohns, Feifan Ouyang, Karl‐Heinz Kück, Andreas Metzner,
emerged as an effective treatment option for symptomatic atrial fibrillation (AF).The current study sought to assess the impact of different ablation protocols on the incidence and characteristics of procedural complications in a large patient cohort.........
Tópico(s): Venous Thromboembolism Diagnosis and Management
2017 - Oxford University Press | EP Europace
Enida Cero, Jasmina Baraković Husić, Sabina Baraković,
The numerous and diverse applications of the Internet of Things (IoT) have the potential to change all areas of daily life of individuals, businesses, and society as a whole. The vision of a pervasive IoT spans a wide range of application domains and addresses the enabling technologies needed to meet the performance requirements of various IoT applications. In order to accomplish this vision, this paper aims to provide an analysis of literature in order to propose a new classification of IoT applications, ...
Tópico(s): IoT Networks and Protocols
2017 - Multidisciplinary Digital Publishing Institute | Symmetry