Alessandro Putzu, Michele Gallo, Enrico Antonio Martino, Enrico Ferrari, Giovanni Pedrazzini, Tiziano Moccetti, Tiziano Cassina,
Background Despite several clinical studies, efficacy of coronary artery bypass grafting (CABG) surgery versus percutaneous coronary intervention (PCI) in patients with left main (LM) disease remains controversial. The objective of this meta-analysis of randomized trials was to evaluate the clinical outcome of CABG versus PCI with drug-eluting stents in LM coronary disease. Methods We systematically searched online databases up to March 2017 for randomized trials comparing CABG to PCI with drug-eluting ...
Tópico(s): Cardiac Imaging and Diagnostics
2017 - Elsevier BV | International Journal of Cardiology
Lisa Carraro, Michela Maifreni, Ingrid Bartolomeoli, Maria Elena Martino, Enrico Novelli, F. Frigo, Marilena Marino, Barbara Cardazzo,
The microbial community in milk is of great importance in the manufacture of traditional cheeses produced using raw milk and natural cultures. During milk curdling and cheese ripening, complex interactions occur in the microbial community, and accurate identification of the microorganisms involved provides essential information for understanding their role in these processes and in flavor production. Recent improvements in molecular biological methods have led to their application to food matrices, ...
Tópico(s): Genomics and Phylogenetic Studies
2011 - Elsevier BV | Research in Microbiology
Laura Mele, Peter D. Sly, Claudia Calogero, Roberto Bernardini, Elio Novembre, Chiara Azzari, Maurizio de Martino, Enrico Lombardi,
To determine and validate a cut-off value for bronchodilation using the interrupter resistance (Rint) in preschool children.Rint was measured in 60 healthy children (age range 2.7-6.4 years) before and after salbutamol inhalation (200 microg). Four potential methods for assessing BDR were evaluated: percent change from baseline, percent change of predicted values, absolute change in Rint, and change in Z-score. These cut-off values, determined as the fifth percentile of the healthy group, were applied ...
Tópico(s): Cystic Fibrosis Research Advances
2010 - Wiley | Pediatric Pulmonology
Daniele Marrelli, Corrado Pedrazzani, Giovanni Corso, Alessandro Neri, Marianna Martino, Enrico Pinto, Franco Roviello,
In Brief Objective: To compare clinicopathological features and long-term outcome in gastric cancer patients coming from high-risk and low-risk areas of Italy. Summary Background Data: Better survival rates have been reported from countries with higher incidence of gastric cancer. Methods: Data regarding 829 patients coming from Tuscany (group A) and 143 patients coming from Southern Italy (group B) were analyzed. Mean follow-up time was 56 ± 57 months; it was 85 ± 63 months in surviving patients or not ...
Tópico(s): Genetic factors in colorectal cancer
2009 - Lippincott Williams & Wilkins | Annals of Surgery
Arturo Chieregato, Alberto Noto, A. Tanfani, Giovanni Bini, Costanza Martino, Enrico Fainardi,
OBJECTIVE To verify the values and the time course of regional cerebral blood flow (rCBF) in the cortex located beneath an evacuated acute subdural hematoma (SDH) and their relationship with neurological outcome. METHODS rCBF levels were measured in multiple regions of interest, by means of a Xe-computed tomographic technique, in the cortex underlying an evacuated SDH and contralaterally in 20 patients with moderate or severe traumatic brain injury and an evacuated acute SDH. Twenty-three patients ...
Tópico(s): Cardiac Arrest and Resuscitation
2009 - Lippincott Williams & Wilkins | Neurosurgery
Sandra Brogioni, P Viacava, Luca Tomisti, E Martino, Enrico Macchia,
Papillary thyroid carcinoma is a slow growing tumor with low metastatic potential. The most frequent sites of distant metastases are lung and bone; less frequent sites are brain, liver, kidney, and skin. Ovarian metastases from papillary thyroid carcinoma are exceptional. We describe a case of bilateral ovarian metastases from a papillary thyroid carcinoma associated with autoimmune thyroiditis in a 38-year-old woman who underwent thyroidectomy and cervical lymph-node dissection 7 years before, ...
Tópico(s): Thyroid Cancer Diagnosis and Treatment
2007 - Thieme Medical Publishers (Germany) | Experimental and Clinical Endocrinology & Diabetes
Valentina Maggini, Gabriele Buda, Sara Galimberti, Alessandro Di Martino, Enrico Orciuolo, Fortunato Morabito, Roberto Bono, Roberto Barale, Mario Petrini, Anna Maria Rossi,
Individual differences in xenobiotica metabolising capacity can influence susceptibility to multiple myeloma. NQO1 and GSTT1 polymorphisms were recently reported as risk factors for multiple myeloma and GSTP1 genotype was found to be a prognostic marker for therapy outcome in multiple myeloma. The aim of this study was to determine whether specific defective alleles of NQO1 (P187S) and GSTP1 (I105V) genes are associated with increased risk of multiple myeloma. Individual genotypes of 128 patients ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2007 - Elsevier BV | Leukemia Research
E. De Lauro, S. De Martino, Enrico Esposito, M. Falanga, E. P. Tomasini,
Several experiments have been performed to investigate the mechanical vibrations associated with an organ pipe. The measurements have been made by using laser Doppler vibrometry, a well-known not-invasive optical measurement technique that is very widely used in structural dynamics. The recorded signals are analyzed by using a well-established decomposition method in time domain, i.e., independent component analysis. Asymptotic dynamics methods to recognize low-dimensional dynamic system associated ...
Tópico(s): Neural dynamics and brain function
2007 - Acoustical Society of America | The Journal of the Acoustical Society of America
Carlo Cappelli, Elena Gandossi, Maurizio Castellano, Claudio Pizzocaro, Barbara Agosti, Andrea Delbarba, Ilenia Pirola, Elvira De Martino, Enrico Agabiti Rosei,
In most trials, at least 30-60% of patients with Graves' disease treated with antithyroid drugs relapse within 2 years after therapy withdrawal. At present, there are no prognostic parameters available early in treatment to indicate patients likely to achieve long-term remission. Because thyrotropin receptor autoantibodies (TRAb) are specific for Graves' disease, we evaluated the ability of their levels and of their rate of change to predict long-term prognosis. In our study 216 consecutive patients ...
Tópico(s): Erythrocyte Function and Pathophysiology
2007 - Japan Endocrine Society | Endocrine Journal
Carlo Cappelli, Elena Gandossi, Barbara Agosti, B. Cerudelli, Davide Cumetti, Maurizio Castellano, Ilenia Pirola, Elvira De Martino, Enrico Agabiti Rosei,
The somatostatin analogue lanreotide is effective in reducing growth hormone levels in patients with acromegaly. Acromegaly is characterized by calcium homeostasis alterations. The aim of our study was to evaluate the effects of lanreotide on bone turnover markers in a group of acromegalic patients and to verify a possible increase of intact parathormone (iPTH) levels in a transient or persistent way. Serum GH, IGF-I and serum and urinary markers of bone metabolism were measured before treatment ...
Tópico(s): Ophthalmology and Eye Disorders
2004 - Japan Endocrine Society | Endocrine Journal
Giuseppe Bartoli, Marcella Bosco, Emanuela Di Martino, Enrico Marcantoni, Letizia Sambri,
A highly efficient and stereoselective technique for additions to syn-β-alkyl-β-hydroxy-α-methyl ketones is now available. The methodology is based on the conversion of the starting material into a trichlorotitanium alkoxide derivative, which is able to assume a stable cyclic arrangement exhibiting high stereofacial discrimination towards nucleophilic alkyl transfer by an appropriate organometallic species. The use of Grignard reagents has serious limitations; in fact, highly hindered and basic ...
Tópico(s): Oxidative Organic Chemistry Reactions
2001 - Wiley | European Journal of Organic Chemistry
E. Martino, Enrico Macchia, F. Aghini-Lombardi, Alessandro Antonelli, M Lenziardi, Roberto Concetti, G. F. Fenzi, L Baschieri, Aldo Pinchera,
Amiodarone, an iodine containing drug, may induce thyrotoxicosis by an uncertain mechanism. In this study the role of thyroid autoimmunity was evaluated in 28 consecutive patients referred to us because they had become hyperthyroid during long-term amiodarone administration. Titres of thyroglobulin and thyroid microsomal antibodies, TSH binding-inhibitory and thyroid stimulating antibodies were evaluated. Underlying thyroid disorders were demonstrated in 20 patients (9 of them had toxic diffuse goitre, ...
Tópico(s): Ion channel regulation and function
1986 - Wiley | Clinical Endocrinology
Alain Jody Corso, Enrico Tessarolo, Martino Guidolin, Enrico Della Gaspera, Alessandro Martucci, Marco Angiola, Alberto Donazzan, Maria Guglielmina Pelizzo,
Palladium thin films of different thicknesses have been processed by oxidation and subsequent reduction in hydrogen atmosphere. Hydrogen optical sensing properties of as-deposited (Pd) and processed (r-Pd) samples have been experimentally tested with a H2 concentration of 5% and 1%, discovering that the reduced films show improved performances in term of response/recovery time. As reveled by SEM images, the oxidation/reduction process modifies the surface appearance, which assumes a nano-islands structured ...
Tópico(s): Analytical Chemistry and Sensors
2018 - Elsevier BV | International Journal of Hydrogen Energy
Moira Barbieri, Daniela Di Martino, Enrico Mario Ferrazzi, Tamara Stampalija,
Placental blood supply to the fetus can be measured by evaluating the umbilical vein blood flow. Despite its potential application in healthcare, the umbilical vein blood flow volume is still used only in research setting. One of the reasons is a concern regarding its reproducibility, partly due to technology issues. Nowadays, technology improvements make this evaluation accurate and reproducible. The aim of this review is to refresh basic elements of the physiology of umbilical vein blood flow ...
Tópico(s): Gestational Diabetes Research and Management
2023 - Wiley | Journal of Clinical Ultrasound
Alessio Martino, Enrico Maiorino, Alessandro Giuliani, Mauro Giampieri, Antonello Rizzi,
The role performed by a protein is directly connected to its physico-chemical structure. How the latter affects the behaviour of these molecules is still an open research topic. In this paper we consider a subset of the Escherichia Coli proteome where each protein is represented through the spectral characteristics of its residue contact network and its physiological function is encoded by a suitable class label. By casting this problem as a machine learning task, we aim at assessing whether a relation ...
Tópico(s): Bioinformatics and Genomic Networks
2017 - Springer Science+Business Media | Lecture notes in computer science
Piero Pavone, Andrea D. Praticò, Renata Rizzo, Giovanni Corsello, Martino Ruggieri, Enrico Parano, Raffaele Falsaperla,
Megalencephaly and macrocephaly present with a head circumference measurement 2 standard deviations above the age-related mean. However, even if pathologic events resulting in both megalencephaly and macrocephaly may coexist, a distinction between these two entities is appropriate, as they represent clinical expression of different disorders with a different approach in clinical work-up, overall prognosis, and treatment. Megalencephaly defines an increased growth of cerebral structures related to ...
Tópico(s): Genetic and Kidney Cyst Diseases
2017 - Wolters Kluwer | Medicine
Massimiliano Ruscica, Nicola Ferri, Federica Fogacci, Martina Rosticci, Margherita Botta, Silvia Marchianò, Paolo Magni, Sergio D’Addato, Marina Giovannini, Claudio Borghi, Arrigo F.G. Cicero, Martino Morbini, Enrico Bertagnin, Elisa Grandi, Silvia Palmesano, Elisabetta Rizzoli, Riccardo Urso, Giuseppe Derosa, Stefano Bacchelli,
Proprotein convertase subtilisin/kexin type 9 (PCSK9) circulating levels are significantly associated with an increased risk of cardiovascular events. This study aimed to evaluate the relationship between circulating levels of PCSK9 and arterial stiffness, an early instrumental biomarker of cardiovascular disease risk, in a large sample of overall healthy participants.From the historical cohort of the Brisighella Heart Study, after exclusion of active smokers, participants in secondary prevention ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2017 - Wiley | Journal of the American Heart Association
Iván J. Núñez‐Gil, Antonio Fernández-Ortı́z, Charbel Maroun‐Eid, Jia Huang, Rodolfo Romero, Víctor Manuel Becerra‐Muñoz, Aitor Uribarri, Gisela Feltes, Daniela Trabatoni, Inmaculada Fernández‐Rozas, María C. Viana‐Llamas, Martino Pepe, Enrico Cerrato, Maurizio Bertaina, Thamar Capel Astrua, Emilio Alfonso, Alex F. Castro‐Mejía, Sergio Raposeiras‐Roubín, Fabrizio D’Ascenzo, Carolina Espejo Paeres, Jaime Signes‐Costa, Alfredo Bardajı́, Cristina Fernández, Francisco Marı́n, Óscar Fabregat‐Andrés, İbrahim Akın, Vicente Estrada, Carlos Macaya,
The presence of any underlying heart condition could influence outcomes during the coronavirus disease 2019 (COVID-19).The registry HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19, NCT04334291) is an international ambispective study, enrolling COVID-19 patients discharged from hospital, dead or alive.HOPE enrolled 2798 patients from 35 centers in 7 countries. Median age was 67 years (IQR: 53.0-78.0), and most were male (59.5%). A relevant heart disease was present in 682 (24%) cases. ...
Tópico(s): Heart Rate Variability and Autonomic Control
2020 - Via Medica | Cardiology Journal
Jaime Signes‐Costa, Iván J. Núñez‐Gil, Joan B. Soriano, Ramón Arroyo‐Espliguero, Charbel Maroun‐Eid, Rodolfo Romero, Aitor Uribarri, Inmaculada Fernández‐Rozas, Marcos Garcı́a Aguado, Víctor Manuel Becerra‐Muñoz, Jia Huang, Martino Pepe, Enrico Cerrato, Sergio Raposeiras‐Roubín, Adelina González, Francisco Franco-Leon, Lin Wang, Emilio Alfonso, Fabrizio Ugo, Juan Fortunato García-Prieto, Gisela Feltes, Mohammad Abumayyaleh, Carolina Espejo‐Paeres, Jorge Jativa, Álvaro López Masjuan, Carlos Macaya, Juan Antonio Carbonell-Asíns, Vicente Estrada,
Patients with pre-existing respiratory diseases in the setting of COVID-19 may have a greater risk of severe complications and even death. A retrospective, multicenter, cohort study with 5847 COVID-19 patients admitted to hospitals. Patients were separated in two groups, with/without previous lung disease. Evaluation of factors associated with survival and secondary composite end-point such as ICU admission and respiratory support, were explored. 1,271 patients (22%) had a previous lung disease, ...
Tópico(s): COVID-19 and healthcare impacts
2020 - Elsevier BV | Archivos de Bronconeumología
Jorge Gabriel Ruiz-Sánchez, Iván J. Núñez‐Gil, Martín Cuesta, Miguel A. Rubio, Charbel Maroun‐Eid, Ramón Arroyo‐Espliguero, Rodolfo Romero, Víctor Manuel Becerra‐Muñoz, Aitor Uribarri, Gisela Feltes, Daniela Trabattoni, María Molina, Marcos Garcı́a Aguado, Martino Pepe, Enrico Cerrato, Emilio Alfonso, Alex F. Castro‐Mejía, Sergio Raposeiras‐Roubín, L Buzón, Elvira Bondía, Francisco Marı́n, Javier López País, Mohammad Abumayyaleh, Fabrizio D’Ascenzo, Elisa Rondano, Jia Huang, Cristina Fernández, Carlos Macaya, Paz de Miguel Novoa, Alfonso L. Calle‐Pascual, Vicente Estrada Pérez, Isabelle Rünkle,
Dysnatremia is associated with increased mortality in patients with community-acquired pneumonia. SARS-COV2 (Severe-acute-respiratory syndrome caused by Coronavirus-type 2) pneumonia can be fatal. The aim of this study was to ascertain whether admittance dysnatremia is associated with mortality, sepsis, or intensive therapy (IT) in patients hospitalized with SARS-COV2 pneumonia. This is a retrospective study of the HOPE-COVID-19 registry, with data collected from January 1 th through April 31 th , 2020. ...
Tópico(s): Potassium and Related Disorders
2020 - Frontiers Media | Frontiers in Endocrinology
Aitor Uribarri, Iván J. Núñez‐Gil, Álvaro Aparisi, Víctor Manuel Becerra‐Muñoz, Gisela Feltes, Daniela Trabattoni, Inmaculada Fernández‐Rozas, María C. Viana‐Llamas, Martino Pepe, Enrico Cerrato, Thamar Capel-Astrua, Rodolfo Romero, Alex F. Castro‐Mejía, Ibrahim El‐Battrawy, Javier López‐País, Fabrizio D’Ascenzo, Óscar Fabregat‐Andrés, Alfredo Bardajı́, Sergio Raposeiras‐Roubín, Francisco Marı́n, Antonio Fernández-Ortı́z, Carlos Macaya, Vicente Estrada,
Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite its international aggressive extension, with a significant morbidity and mortality, the impact of renal function on its prognosis is uncertain. Analysis from the international HOPE-Registry (NCT04334291). The objective was to evaluate the association between kidney failure severity on admission with the mortality of patients with SARS-CoV-2 infection. Patients were categorized ...
Tópico(s): COVID-19 and healthcare impacts
2020 - Springer Science+Business Media | Journal of Nephrology
Raffaele Falsaperla, Andrea D. Praticò, Martino Ruggieri, Enrico Parano, Renata Rizzo, Giovanni Corsello, Giovanna Vitaliti, Piero Pavone,
Congenital muscular dystrophies (CMDs) are a wide group of muscular disorders that manifest with very early onset of muscular weakness, sometime associated to severe brain involvement.The histologic pattern of muscle anomalies is typical of dystrophic lesions but quite variable depending on the different stages and on the severity of the disorder.Recent classification of CMDs have been reported most of which based on the combination of clinical, biochemical, molecular and genetic findings, but genotype/ ...
Tópico(s): Congenital heart defects research
2016 - BioMed Central | The Italian Journal of Pediatrics/Italian journal of pediatrics
Alessia Casolaro, Josée Golay, Clara Albanese, Roberta Ceruti, Veronica Patton, Sabrina Cribioli, Alice Pezzoni, Marco Losa, Gemma Texidó, Ursula Giussani, Francesco Marchesi, Nadia Amboldi, Barbara Valsasina, Silvia Bungaro, Giovanni Cazzaniga, Alessandro Rambaldi, Martino Introna, Enrico Pesenti, Rachele Alzani,
CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We describe the establishment and characterisation of a novel disseminated model of AML (AML-NS8), generated by injection into mice of leukaemic blasts freshly isolated from a patient with an aggressive CD56(+) monoblastic AML (M5a). The model reproduced typical manifestations of this leukaemia, including presence of extramedullary masses and central ...
Tópico(s): Glioma Diagnosis and Treatment
2013 - Public Library of Science | PLoS ONE
Alessia G Ferrarese, Valter Martino, Stefano Enrico, Alessandro Falcone, Silvia Catalano, Giada Pozzi, Silvia Marola, Mario Solej,
Laparoscopic appendectomy for acute appendicitis is one of the most common surgical procedures performed in the world. We aimed to compare laparoscopic and open appendectomy in the elderly in our experience. We performed a retrospective review of elderly patients who underwent appendectomy for acute appendicitis from 1st of January 2006 to the 31st of July 2012. We analyzed 39 appendectomies in elderly patients: 20 procedures were performed using open technique (Group O) and 19 using laparoscopic ...
Tópico(s): Intestinal Malrotation and Obstruction Disorders
2013 - BioMed Central | BMC Surgery
Alessia G Ferrarese, Valter Martino, Stefano Enrico, Alessandro Falcone, Silvia Catalano, Enrico Gibin, Silvia Marola, A Surace, Mario Solej,
Laparoscopic approach for wound defects is a procedure that aims to reduce surgical aggressiveness against the abdominal wall by using minimal incisions and dedicated instruments. We report our experience about clinical outcome of elderly patients undergoing laparoscopic repair for incisional hernias (Group I) and primary inguinal hernias (Group II) from June 2007 to September 2012. We analyzed preoperative and postoperative data for the laparoscopic approach in the elderly. In our experience there ...
Tópico(s): Abdominal Surgery and Complications
2013 - BioMed Central | BMC Surgery
Pierpaolo Trimboli, Salvatore Ulisse, Michele D’Alò, Fabrizio Solari, Angela Fumarola, Martino Ruggieri, Enrico De Antoni, A Catania, Salvatore Sorrenti, Francesco Nardi, M D’Armiento,
Tópico(s): Biomarkers in Disease Mechanisms
2008 - Wiley | Clinical Endocrinology
Maria Beatrice Chiarini Testa, Martino Pavone, Enrico Bertini, A Petrone, M. Pagani, Renato Cutrera,
Our aim was to assess the respiratory pattern during sleep in patients affected by spinal muscular atrophy types 1 and 2 and to compare their apnea-hypopnea indices with those of controls.All consecutively referred patients underwent polysomnography. Sleep stages were defined as either wake, quiet sleep (QS), or active sleep (AS). As measures of thoracoabdominal coordination, we measured: phase angle during QS and AS (Ph Angle QS and AS), phase relation during inspiration and expiration during QS and ...
Tópico(s): Congenital Anomalies and Fetal Surgery
2005 - Lippincott Williams & Wilkins | American Journal of Physical Medicine & Rehabilitation
Virgilio F. Ferrario, Chiarella Sforza, Gianluca Martino Tartaglia, Enrico Barbini, Giovanni Michielon,
A new television technique that proved to be faster than conventional photographic analysis has been developed and applied to the evaluation of the head and body natural standing posture in 303 healthy children, ages 6 to 11, and in 186 healthy young adults. In the lateral plane all subjects had extended head (soft tissue Frankfurt plane), with parallel Camper's and occlusal planes. The neck was halfway between the horizontal and vertical planes. Most angles significantly correlated with each other. ...
Tópico(s): Cerebral Palsy and Movement Disorders
1995 - Taylor & Francis | CRANIO®
Enrico Martino, Gabriele Usberti,
Tópico(s): Epistemology, Ethics, and Metaphysics
1994 - Springer Science+Business Media | Topoi
Isabella Lupi, Rezene Fessehatsion, Alessandra Manca, Paolo Cossu‐Rocca, Enio Martino, Enrico Macchia,
Ectopic thyroid tissue in ovarian teratoma or in struma ovarii appears to be histologically identical to the thyroid gland tissue and may virtually exhibit all the pathological patterns found in the thyroid gland. However, the concurrent lymphocytic infiltration of the thyroid gland, as found in Hashimoto's thyroiditis, and of the ectopic thyroid tissue is extremely rare. We describe the case of an 18-years old patient, in which a right ovarian 4 cm cyst has been found during pelvic ultrasound exam. ...
Tópico(s): Urticaria and Related Conditions
2011 - Informa | Gynecological Endocrinology