Javier Ávalos, Enrique Cerdá‐Olmedo,
Tópico(s): Algal biology and biofuel production
1987 - Springer Science+Business Media | Current Genetics
Javier Ávalos, Enrique Cerdá‐Olmedo,
The wild type of the fungus Gibberella fujikuroi has no carotenoids in the dark and only moderate amounts in the light. The deep-orange mutant SG22 accumulates large amounts of carotenoids both in the light and the dark. The predominant compound is always neurosporaxanthin. β-Ionone and diphenylamine inhibit phytoene dehydrogenation, with concomitant loss of mycelial colour. A significant accumulation of lycopene has been observed only in the presence of high concentrations of α-picoline. Ethanol, ...
Tópico(s): Plant biochemistry and biosynthesis
1986 - Elsevier BV | Phytochemistry
Reyes Candau, Javier Ávalos, Enrique Cerdá‐Olmedo,
A new screening procedure was used to isolate 14 gib mutants of Gibberella fujikuroi with modifications in the production of gibberellins. The production of carotenoids and gibberellins was investigated in the gib mutants and in representative car mutants with various modifications of carotenoid biosynthesis. The determinations of gibberellins were carried out with a simplified fluorescence method. One of the mutants lacked both gibberellins and carotenoids. In many mutants the two pathways compensated ...
Tópico(s): Diatoms and Algae Research
1991 - American Society for Microbiology | Applied and Environmental Microbiology
Reyes Candau, Javier Ávalos, Enrique Cerdá‐Olmedo,
Gibberellin production by Gibberella fujikuroi started only after the nitrogen source was depleted and ceased upon its renewal. Nitrogen repression of gibberellin biosynthesis is not an indirect effect of the growth arrest that follows the depletion of an essential nutrient because gibberellins were not produced upon depletion of phosphate. Mycelia produced gibberellins when suspended in a glucose solution. Production ceased some time after depletion of glucose and resumed upon its readdition. Under ...
Tópico(s): Slime Mold and Myxomycetes Research
1992 - Oxford University Press | PLANT PHYSIOLOGY
Irina Obraztsova, Nicolás Prados, Klaus Holzmann, Javier Ávalos, Enrique Cerdá‐Olmedo,
Introduction of plasmids in Phycomyces blakesleeanus caused extensive changes in the exogenous DNA and in the resident genome. Plasmids with a bacterial gene for geneticin resistance under a Phycomyces promoter were either injected into immature sporangia or incubated with spheroplasts. An improved method produced about one viable spheroplast per cell. Colonies resistant to geneticin were rare and only about 0.1% of their spores grew in the presence of geneticin. The transformation frequency was ...
Tópico(s): Bacterial Genetics and Biotechnology
2003 - Academic Press | Fungal Genetics and Biology
Javier Ávalos, Enrique Cerd√°-Olmedo,
Tópico(s): Plant biochemistry and biosynthesis
2003 - CRC Press | Mycology
Javier Ávalos, Enrique Cerdá‐Olmedo, Fernando Reyes, Alejandro F. Barrero,
The rich metabolism of the fungal strains, now classified as Fusarium fujikuroi and related species covers the production of many secondary products, including different terpenoids and polyketides. Research has concentrated on the gibberellins, growth-promoting plant hormones with multiple applications in agriculture and brewing. The long list of secondary metabolites includes pigments such as carotenoids and bikaverins, mycotoxins such as fusarins and fumonisins and a diversity of other compounds, ...
Tópico(s): Fungal Biology and Applications
2007 - Bentham Science Publishers | Current Organic Chemistry
José Guadalupe Martínez-Ávalos, Enrique Jurado,
Tópico(s): Botany and Geology in Latin America and Caribbean
2005 - Springer Science+Business Media | Biodiversity and Conservation
Carlos E. Domenech, Walter Giordano, Javier Ávalos, Enrique Cerdá‐olmedo,
Substrate flows in the sterol, carotenoid and gibberellin pathways of Gibberella fujikuroi were examined by isotope‐dilution experiments. The wild type and two carotenoid mutants of this fungus were grown in minimal medium with abundant glucose, limiting ammonium nitrate and a radioactively labelled precursor (either acetate, mevalonate or leucine). The precursors did not affect growth or terpenoid production, with two exceptions; leucine allowed additional growth, as expected from the nitrogen limitation ...
Tópico(s): Fungal Biology and Applications
1996 - Wiley | European Journal of Biochemistry
R. Fernández-Martín, Fernando Reyes, Carlos E. Domenech, Eduardo Cabrera, Peter M. Bramley, Alejandro F. Barrero, Javier Ávalos, Enrique Cerdá‐Olmedo,
The Ascomycete Gibberella fujikuroi synthesizes gibberellins, fujenal, carotenoids, and other terpenoids. Twelve gib mutants, isolated through the modified gibberellin fluorescence of their culture media, were subjected to chemical and biochemical analyses. Two mutants were specifically defective in the hydroxylation of carbon 13; their total gibberellin production was normal, but their main gibberellin was GA7 instead of GA3. Four mutants were blocked in the early reactions between geranylgeranyl ...
Tópico(s): Fern and Epiphyte Biology
1995 - Elsevier BV | Journal of Biological Chemistry
Walter Giordano, Javier Ávalos, Enrique Cerdá-Olmedo, Carlos E. Domenech,
Production of bikaverin and gibberellins by Gibberella fujikuroi started after depletion of the nitrogen source, but not after depletion of phosphate. Despite this similarity, the regulation of both pathways by nitrogen involved two different mechanisms. This conclusion was supported by the fact that the production of bikaverin, in contrast to the gibberellins, was not inhibited by nitrate in a mutant that could not utilize it. The different regulation of both pathways was clearly demonstrated by ...
Tópico(s): Mycorrhizal Fungi and Plant Interactions
1999 - Oxford University Press | FEMS Microbiology Letters
Rocı́o Sánchez-Fernández, Javier Ávalos, Enrique Cerdá‐Olmedo,
Gibberellin production in Gibberella fujikuroi starts upon exhaustion of the nitrogen source. To determine the role of nitrate and ammonium in the regulation of gibberellin biosynthesis we have isolated mutants that cannot use nitrate as a nitrogen source. Nitrate inhibited partially the production of gibberellins in mutants devoid of nitrate reductase activity. The inhibition occurred whether nitrate was added before or after the onset of gibberellin production. Addition of tungstate to the wild ...
Tópico(s): Plant nutrient uptake and metabolism
1997 - Wiley | FEBS Letters
Heriberto Pfeiffer, Tatiana L. Ávalos-Rendón, Enrique Lima, Jaime S. Valente,
Hydrocalumite ([Ca2Al(OH)6]2CO3·mH2O) was synthesized by precipitation and thermally activated at 300 and 550°C. Its CO2 chemisorption capacity was evaluated and compared with that of calcium oxide (CaO). Initial thermal analyses showed that CaAl-550 sample has better properties as CO2 sorbent than CaO, evaluated under similar conditions. It was determined that both materials (CaAl-550 and CaO) have similar kinetic behavior, and the presence of Ca12Al14O33 on the CaAl-550 sample did not reduce or interfere ...
Tópico(s): Carbon Dioxide Capture Technologies
2011 - American Society of Civil Engineers | Journal of Environmental Engineering
Produção Nacional
Revisado por pares
J. Lopez, Félix G. Requejo, A. F. Craievich, J. Wei, M. Ávalos‐Borja, Enrique Iglesia,
Pt cluster size strongly influences the reactivity of surfaces for CH bond activation during CH4 steam reforming. CH bond activation turnover rates for H2O reforming of CH4 increased with decreasing Pt cluster size, suggesting that coordinatively unsaturated surface Pt atoms are more reactive than Pt atoms in low-index surfaces prevalent in larger clusters. Near-edge fine structure in X-ray absorption spectra clearly shows electronic changes in Pt clusters relative to bulk Pt crystallites, though ...
Tópico(s): Catalysis and Oxidation Reactions
2004 - Elsevier BV | Journal of Molecular Catalysis A Chemical
Federico Ávila‐Moreno, Leonel Armas‐López, Aldo M. Álvarez-Moran, Zoila A. Lopez‐Bujanda, Blanca Ortíz-Quintero, Alfredo Hidalgo‐Miranda, Francisco Urrea, Rosa María Rivera-Rosales, Eugenia Vázquez-Manríquez, Erika Sagrario Peña-Mirabal, José Morales-Gómez, Juan Carlos Vázquez-Minero, José Luis Téllez-Becerra, Roberto Ramírez-Mendoza, Alejandro Ávalos-Bracho, Enrique Guzmán de Alba, Karla Vázquez-Santillan, Vilma Maldonado‐Lagunas, Patricio Santillán‐Doherty, Patricia Piña‐Sánchez, Joaquı́n Zúñiga,
Lung cancer is the leading cause of death from malignant diseases worldwide, with the non-small cell (NSCLC) subtype accounting for the majority of cases. NSCLC is characterized by frequent genomic imbalances and copy number variations (CNVs), but the epigenetic aberrations that are associated with clinical prognosis and therapeutic failure remain not completely identify. In the present study, a total of 55 lung cancer patients were included and we conducted genomic and genetic expression analyses, ...
Tópico(s): RNA modifications and cancer
2014 - Public Library of Science | PLoS ONE
Kenichiro Fujimoto, Fabio H. Ribeiro, M. Ávalos‐Borja, Enrique Iglesia,
The kinetics of methane combustion at low temperatures are consistent with a Mars–van Krevelen redox mechanism involving the activation of methane on site pairs consisting of oxygen atoms and oxygen vacancies on the surface of PdOxcrystallites. H2O strongly inhibits methane oxidation rates by titrating surface vacancies in a quasi-equilibrated adsorption–desorption step. Initial activation periods during methane oxidation are related to the presence of oxygen-deficient PdOxcrystallites, which contain ...
Tópico(s): Luminescence Properties of Advanced Materials
1998 - Elsevier BV | Journal of Catalysis
Samuel L. Leung, J. Wei, W.L. Holstein, M. Ávalos‐Borja, Enrique Iglesia,
CH4–CO2 and CH4–H2O reforming on Ni-based catalysts can lead to the undesired formation of carbonaceous residues. The dynamics of the formation of carbon filaments and encapsulating layers on dispersed Ni nanoparticles (5–11 nm diameter) are determined here using an inertial microbalance to measure mass changes and mass spectrometry to concurrently assess turnover rates under conditions of reforming practice (800–1000 K). The morphology and rate of formation of carbonaceous species were controlled ...
Tópico(s): Zeolite Catalysis and Synthesis
2020 - American Chemical Society | The Journal of Physical Chemistry C
M. Montero, Marisa Mir, Elena Sulleiro, J.L. Avalos Esquivel, Enrique García López, Daniel Molina‐Morant, Inmaculada López-Montesinos, Luisa Sorlí, Gerard Espinosa, E. Mounteis Oliva, Marta Crespo, Inés Monge‐Escartín, Juan Pablo Horcajada, S Grau, J. Pascual,
There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.
Tópico(s): Complement system in diseases
2018 - Elsevier BV | International Journal of Infectious Diseases
Javier Ávalos, Josep Casadesús, Enrique Cerdá‐Olmedo,
N-methyl-N'-nitro-N-nitrosoguanidine (nitrosoguanidine) and to a lesser extent UV radiation are very mutagenic for Gibberella microconidia. The recommended nitrosoguanidine doses lead to much higher frequencies of mutants than are found in other microorganisms. The frequency of mutants among the survivors increases linearly with the nitrosoguanidine dose (molar concentration X time); the absolute number of viable mutants in a given population reaches a maximum for a dose of ca. 0.7 M X s. The microconidia ...
Tópico(s): Biocrusts and Microbial Ecology
1985 - American Society for Microbiology | Applied and Environmental Microbiology
Eduardo R. Bejarano, Javier Ávalos, EdwardD. Lipson, Enrique Cerdá‐Olmedo,
Tópico(s): Plant and Biological Electrophysiology Studies
1991 - Springer Science+Business Media | Planta
José Luis Reyes-Araiza, Alejandro Manzano-Ramírez, J.C. Rubio-Ávalos, Enrique González-Sosa, J.F. Pérez‐Robles, M. Arroyo-Contreras, Christian Signoret, Eduardo Castillo-Castañeda, Yu. V. Vorobiev,
Tópico(s): Smart Materials for Construction
2008 - Pleiades Publishing | Inorganic Materials
Javier Ávalos, Eduardo R. Bejarano, Enrique Cerdá‐Olmedo,
The biosynthesis of carotenoids is almost universally regulated by light. A partial explanation is provided by the role of carotenoids in photosynthesis. Light is a source of information for many organisms that do not use it as a source of energy. Carotenogenesis is one of the aspects of life that are modulated by light in these organisms. In some cases, no carotenoids are made in the dark; most often small amounts of carotenoids are made in the dark, but much more in the light. Light governs other ...
Tópico(s): Antioxidant Activity and Oxidative Stress
1993 - Academic Press | Methods in enzymology on CD-ROM/Methods in enzymology
David Weinkove, Juan A. Poyatos, Heribert Greiner, Enrique Oltra, Javier Ávalos, Leonid Fukshansky, Alejandro F. Barrero, Enrique Cerdá‐Olmedo,
Weinkove, D., Poyatos, J. A., Greiner, H., Oltra, E., Avalos, J., Fukshansky, L., Barrero, A. F., and Cerdá-Olmedo, E. 1998. Mutants ofPhycomyceswith decreased gallic acid content.Fungal Genetics and Biology25, 196–203. Most plants and some fungi accumulate phenols. Two hydroxybenzoic acids, gallic and protocatechuic acids, are abundant in the giant sporangiophores of the zygomycetePhycomyces blakesleeanus,much more so than in the basal mycelium or the culture medium. The actual concentrations vary ...
Tópico(s): Fungal Biology and Applications
1998 - Academic Press | Fungal Genetics and Biology
Luis M. Salgado, Javier Ávalos, Eduardo R. Bejarano, Enrique Cerdá‐Olmedo,
Abstract External stimuli and mutations in several car genes modify the β-carotene content of the fungus Phycomyces blakesleeanus. Cell-free extracts from unstimulated agar-grown wild-type mycelia incorporate radioactivity from sodium [2-14C]mevalonate into carotenes and squalene, in relative proportion of ca 3: 100. Higher incorporations into carotenes are found in extracts from (i) mycelia grown in the light or in the presence of retinol or dimethyl phthalate, although these agents have no effect ...
Tópico(s): Antioxidant Activity and Oxidative Stress
1991 - Elsevier BV | Phytochemistry
José Guadalupe Martínez-Ávalos, Jordán Golubov, María C. Mandujano, Enrique Jurado,
Little is known about the causes of mortality in natural populations of threatened cactus species. In particular we focus on the endangered Astrophytum asterias in four populations where most individuals of the species are found. At two sites one of each vegetation type (Tamaulipan thornscrub [TS] and Piedmont thornscrub [PT]) we measured individual mortality by three causes: the plant pathogen Phytophtora infestans, a cerambicid beetle and the terrestrial squirrel Spermophilus mexicanus. We found ...
Tópico(s): Plant and animal studies
2007 - Elsevier BV | Journal of Arid Environments
Sara Rondón‐Avalo, Carolina Rodríguez‐Medina, Javier Enrique Botero,
Abstract Background Down syndrome (DS) is distinguished by cognitive disability, a concave profile, and systemic complications. Oral diseases have been reported to be common in DS patients. Objective To investigate the association between DS and periodontal diseases. Methods Two independent reviewers searched six bibliographic databases up to January 2023 and used additional search methods to identify published studies on gingivitis or periodontitis in people with and without DS. Meta‐analysis, risk ...
Tópico(s): Dental Health and Care Utilization
2023 - Wiley | Special Care in Dentistry
Produção Nacional
Revisado por pares
Kristel Kegler Pangrazio, É.A. Costa, Shyrley Paola Amarilla, Ada G. Cino, Teane M. A. Silva, Tatiane A. Paíxão, Luciana Fachini da Costa, Enrique G. Dengues, Andres Avalos Ruiz Diaz, Renato L. Santos,
Visceral leishmaniasis (VL) is primarily transmitted by an invertebrate vector, but transmission in the absence of the vector has been reported. Vertical transmission of VL has been described in man and dogs. The aim of this study was to evaluate the distribution of Leishmania amastigotes in fetal organs and histopathologic changes associated with parasitism and to determinate the frequency of transplacental transmission and potential of vertical transmission by symptomatic and asymptomatic pregnant ...
Tópico(s): Reproductive System and Pregnancy
2009 - Elsevier BV | Veterinary Parasitology
R. Fernández-Martín, Enrique Cerdá‐Olmedo, Javier Ávalos,
Tópico(s): Plant-Microbe Interactions and Immunity
2000 - Springer Science+Business Media | MGG Molecular & General Genetics
R. Fernández-Martín, Carlos E. Domenech, Enrique Cerdá‐Olmedo, Javier Ávalos,
Sterols and gibberellins are the main terpenoids in the Ascomycete Fusarium fujikuroi. Their respective precursors squalene and ent-kaur-16-ene (henceforth called kaurene) were the main terpenoids synthesised from radioactive mevalonate by extracts of F. fujikuroi in vitro. Kaurene predominated when the extracts were obtained from mycelia engaged in gibberellin production. Squalene predominated in all other cases, and particularly when the extracts were obtained from mutants with various defects ...
Tópico(s): Microbial Natural Products and Biosynthesis
2000 - Elsevier BV | Phytochemistry
Nabil Arrach, R. Fernández-Martín, Enrique Cerdá‐Olmedo, Javier Ávalos,
Previous complementation and mapping of mutations that change the usual yellow color of the Zygomycete Phycomyces blakesleeanus to white or red led to the definition of two structural genes for carotene biosynthesis. We have cloned one of these genes, carRA , by taking advantage of its close linkage to the other, carB , responsible for phytoene dehydrogenase. The sequences of the wild type and six mutants have been established, compared with sequences in other organisms, and correlated with the mutant ...
Tópico(s): Microbial Natural Products and Biosynthesis
2001 - National Academy of Sciences | Proceedings of the National Academy of Sciences