Jeremy Rundall, W G E Jackson, Anthony Burgess, Nicholas Lloyd Education Correspondent, Charles Raw, Richard Buckle, Oliver Stanley, J F Axisa, Nicholas Carroll Diplomatic Correspondent, Philip Norman, John Woodcock cricket correspondent of The Times, John Peter, Peter Marson, Ian Peebles, Scilly Isles, Kenneth Pearson, John Moon, John Miles, Antony Terry, Percy Silberston, Nicholas Lloyd, George Schwartz Column, Julian Symons, Frederic Raphael, Jack Smith, Cal McCrystal, Mary Newcombe, Philip Oakes, Colin Simpson, Henry Brandon, John Fielding Air Correspondent, Vivian Lewis, John Russell, Richard Milner, Linda Blandford, Ly Chinly, R C W Bayley, Derek Jewell, Vivian Jenkins, Christopher Lucas, Murray Sayle, Nova Phillstruck, (Mrs) Vera MacArov, Timothy Johnson, Bryan Silcock Science Correspondent, Tony Conyers, Sandy Bolert, Cyril Connolly, Philip J Bond, Jeremy Clive, John Fielding, E F, Michael Howard, Raymond Mortimer, Boris Schapiro, Maxwell Boyd, Tony Geraghty, Rex Smith, Persimmon Mince, G R D Forde, Frank Dorsey, Peter Wilsher, Bryan Silcock, Roger Mortimer, Eric Jacobs, Malcolm Winton, John Raymond, John L Newton, Ernestine Carter, S B, Edwin Reed, Richard Garrick, Desmond Shawe-Taylor, John Arden, Robert Conquest, B M Gosden, Stephen Aris, R. Postill, Alexander Mitchell, William Osler, Andrew Mulligan, Dilys Powell, Jean A Bond, Philips Oakes, L vd P, Richard Hughes, Andrew Sinclair, Felix Aprahamian, Roger Lewis, Michael Field, Jack Fingleton, Patricia Rowan, David Leitch, Arnold Field, Margaret Costa, J W Lambert, Henry Longhurst, Stephen Fay, Edward Kennedy, (Rev) John Dennis, Evelyn Forbes, Richard Burnell, James Margach Political Correspondent, Adam Frost, Bryher, Michael Moynihan, Brian Glanville, Lucia van der Post, Graham Searjeant, Peter Dunn, John A Cullinane, R J P Grunt, C. H. O'd. Alexander, Raymond Brooks-Ward, Maurice Wiggin, Howard Fry, Bob Millard, Polly Devlin, Michael Parkinson, Sirhan Bishara Sirhan, Phillip Knightley, Harlow Unger, Anthony Cowdy, James Dow, Malcolm Crawford, Ruth First, Kenneth Konstam, Muriel Bowen, Nicholas Tomalin,
... 5s From the Pigs to the Pines Fidel Castro by Enrique Meneses/Faber 42s The lessons of independence Reap ...
1968 - Gale Group | Sunday Times HA GDA
Marta Molina, Encarnación Castro, Enrique Castro,
Design research is a methodological paradigm, mainly qualitative, that is currently being intensely applied and developed in educational research. In this work we briefly describe this methodology and, within it, we focus our attention on a specific type of studies: teaching experiments. After describing the main characteristics of these studies, we present some conclusions that have been obtained in two teaching experiments developed by the authors. This information may contribute, directly or ...
Tópico(s): Open Education and E-Learning
2007 - | The International Journal of Interdisciplinary Social Sciences Annual Review
Marta Molina, Encarnación Castro, Enrique Castro,
Introducción. Movidos por nuestro interés en la propuesta curricular de integración del pensamiento algebraico en las matemáticas de educación primaria, analizamos la comprensión de igualdades y sentencias numéricas de un grupo de estudiantes de primaria y su evolución cuando trabajan en la resolución de igualdades abiertas y sentencias numéricas verdaderas y falsas.Método. Se llevó a cabo un experimento de enseñanza, con un grupo de estudiantes de entre ocho y nueve años, que comparte las características ...
Tópico(s): Statistics Education and Methodologies
2017 - University of Almería | Electronic Journal of Research in Educational Psychology
Alison Holmes, Enrique Castro‐Sánchez, Raheelah Ahmad,
... in infection prevention: Current challenges and limitationsAlison Holmes, Enrique Castro-Sánchez, Raheelah AhmadAlison Holmes, Enrique Castro-Sánchez, Raheelah AhmadAlison Holmes; Enrique Castro-Sánchez; Raheelah AhmadPublished Online:10 Jun 2015https://doi. ...
Tópico(s): Healthcare Decision-Making and Restraints
2015 - Mark Allen Group | British Journal of Healthcare Management
Marta Molina González, Encarnación Castro Martínez, José Luis Molina-González, Enrique Castro Martínez,
La Investigación de Diseño (Design Research) es un paradigma metodológico relativamente joven que está siendo de gran utilidad en el campo de la Didáctica de las Ciencias. En este trabajo aportamos una descripción general de dicho paradigma centrándonos en más detalle en la metodología concreta de los experimentos de enseñanza. Presentamos y ejemplificamos las principales características de este tipo de estudios, enriqueciendo la descripción aportada por la literatura con las conclusiones extraídas ...
Tópico(s): Educational Research and Science Teaching
2011 - Autonomous University of Barcelona | Enseñanza de las Ciencias Revista de investigación y experiencias didácticas
Javier Prior, Enrique Castro, Alex W. Chin, J. R. L. de Almeida, Susana F. Huelga, Martin B. Plenio,
New experimental techniques based on non-linear ultrafast spectroscopies have been developed over the last few years, and have been demonstrated to provide powerful probes of quantum dynamics in different types of molecular aggregates, including both natural and artificial light harvesting complexes. Fourier transform-based spectroscopies have been particularly successful, yet 'complete' spectral information normally necessitates the loss of all information on the temporal sequence of events in a ...
Tópico(s): Photoreceptor and optogenetics research
2013 - American Institute of Physics | The Journal of Chemical Physics
Jesús Mateo, Enrique Castro, Jean Zwiller, Dominique Aunis, Marı́a Teresa Miras-Portugal,
Abstract: We investigated the effect of the adenosine receptor agonist 5′‐( N ‐ethylcarboxamido)adenosine (NECA) in catecholamine secretion from adrenal chromaffin cells that exhibit only the A 2b subtype adenosine receptor. NECA reduced catecholamine release evoked by the nicotinic agonist 1,1‐dimethyl‐4‐phenylpiperazinium (DMPP) in a time‐dependent manner. Inhibition reached 25% after 30–40‐min exposure to NECA. This effect on DMPP‐evoked catecholamine secretion was mirrored by a similar (27.7 ± 3.3%), ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
1995 - Wiley | Journal of Neurochemistry
Enrique Castro, Jesús Mateo, Ângelo R. Tomé, Rui M. Barbosa, Marı́a Teresa Miras-Portugal, Luı́s M. Rosário,
We have assessed the relative contribution of Ca2+ entry and Ca2+ release from internal stores to the [Ca2+]i transients evoked by purinergic receptor activation in bovine adrenal chromaffin cells. The [Ca2+]i was recorded from single cells using ratiometric fura-2 microfluorometry. Two discrete groups of ATP-sensitive cells could be distinguished on the basis of their relative capacity to respond to ATP in the virtual absence of extracellular Ca2+. One group of cells (group I) failed to respond to ...
Tópico(s): Neuropeptides and Animal Physiology
1995 - Elsevier BV | Journal of Biological Chemistry
Lisandro Giráldez, Miguel Díaz‐Hernández, Rosa Gómez‐Villafuertes, Jesús Pintor, Enrique Castro, M. Teresa Miras‐Portugal,
Abstract Synaptosomal preparations from rat midbrain exhibit specific responses to both ATP and Ap 5 A, which stimulate a [Ca 2+ ] i increase in the presynaptic terminals via specific ionotropic receptors, termed P2X , and diadenosine polyphosphate receptors. Aminergic terminals from rat brain basal ganglia were characterized by immunocolocalization of synaptophysin and the vesicular monoamine transporter VMAT2 and represent 29% of the total. These aminergic terminals respond to ATP and/or Ap 5 A with ...
Tópico(s): Neuroscience and Neuropharmacology Research
2001 - Wiley | Journal of Neuroscience Research
Enrique Castro‐Sánchez, Elpiniki Spanoudakis, Alison Holmes,
Public involvement in efforts to control the current Ebola virus disease epidemic requires understandable information. We reviewed the readability of Ebola information from public health agencies in non-Ebola-affected areas. A substantial proportion of citizens would have difficulty understanding existing information, which would potentially hinder effective health-seeking behaviors.
Tópico(s): Data-Driven Disease Surveillance
2015 - Centers for Disease Control and Prevention | Emerging infectious diseases
Rafael Vila‐Candel, Francisco Javier Soriano‐Vidal, Enrique Hevilla Cucarella, Enrique Castro‐Sánchez, José M. Martín-Moreno,
Few studies have been carried out in Spain examining the use of tobacco amongst expectant mothers and its effect on birth weight. To observe the proportion of expectant mothers who smoke during their pregnancy, and the impact of tobacco consumption on maternal and birth weight. We also aimed to identify the trimester of pregnancy in which tobacco use produced the greatest reduction in birth weight. Prospective observational study in Spain. A random sampling strategy was used to select health centres ...
Tópico(s): Prenatal Substance Exposure Effects
2015 - Elsevier BV | Women and Birth
Nisha Shah, Enrique Castro‐Sánchez, Esmita Charani, Lydia N. Drumright, Alison Holmes,
BackgroundImproving behaviour in infection prevention and control (IPC) practice remains a challenge, and understanding the determinants of healthcare workers' (HCWs) behaviour is fundamental to develop effective and sustained behaviour change interventions.AimTo identify behaviours of HCWs that facilitated non-compliance with IPC practices, focusing on how appraisals of IPC duties and social and environmental circumstances shaped and influenced non-compliant behaviour. This study aimed to: (1) identify ...
Tópico(s): Healthcare cost, quality, practices
2015 - Elsevier BV | Journal of Hospital Infection
Enrique Castro‐Sánchez, Alison Holmes,
Resolving the challenges presented by healthcare-associated infections requires a 'whole healthcare economy' perspective encompassing the interactions between biological, therapeutic, and structural factors. The importance and influence of organizational characteristics is receiving increasing attention. This article reviews some keys features that can facilitate the success of patient safety initiatives related to healthcare-associated infections, and highlights areas for further consideration and ...
Tópico(s): Patient Satisfaction in Healthcare
2015 - Elsevier BV | Journal of Hospital Infection
Walter Zingg, Enrique Castro‐Sánchez, Federica Secci, Richard Edwards, Lydia N. Drumright, Nick Sevdalis, Alison Holmes,
With the aim to facilitate a more comprehensive review process in public health including patient safety, we established a tool that we have termed ICROMS (Integrated quality Criteria for the Review Of Multiple Study designs), which unifies, integrates and refines current quality criteria for a large range of study designs including qualitative research. Review, pilot testing and expert consensus. The tool is the result of an iterative four phase process over two years: 1) gathering of established ...
Tópico(s): Delphi Technique in Research
2015 - Elsevier BV | Public Health
María A. Umaña, Carla Odio, Enrique Castro, José L. Salas, George H. McCracken,
In a prospective randomized, open study we evaluated aztreonam (AZ) for treatment of neonatal bacterial infections. There were 147 patients enrolled in the study; 75 received AZ and ampicillin (AMP) and 72 amikacin (AM) and AMP (conventional therapy). Twenty-eight AZ/AMP-treated patients and 32 conventionally treated patients had bacteriologically documented infections caused by gram-negative enteric bacilli or Pseudomonas species. Treatment groups were comparable in age, clinical status, and type and ...
Tópico(s): Cystic Fibrosis Research Advances
1990 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Gilbert Madrigal, Carla Odio, E Mohs, José Enrique Castro Guevara, George H. McCracken,
One hundred thirty-two children with acute urinary tract infection were randomly assigned to receive trimethoprim-sulfamethoxazole in one dose, two doses daily for 3 days or two doses daily for 7 days. The patient characteristics, etiologic agents and frequency of roentgenologic abnormalities were similar for the three treatment groups. There was no significant difference in bacteriologic cure rates for the single dose regimen (93%) and multidose regimens (96%). The difference in rates of recurrent ...
Tópico(s): Pediatric Urology and Nephrology Studies
1988 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Fernando Ruiz‐Juretschke, Enrique Castro, O. Mateo-Sierra, Begoña Iza, J.M. Garbizu, Fernando Fortea, Francisco Villoria,
Tópico(s): Vascular Malformations Diagnosis and Treatment
2009 - Springer Science+Business Media | Acta Neurochirurgica
Joaquín Osca, María José Sancho Tello, Josep Navarro, Óscar Cano, Rafael Raso, José Enrique Castro, José Olagüe, Antonio Salvador,
En los últimos años se ha producido una sobrecarga de trabajo en las consultas de dispositivos cardiacos. La monitorización remota permite su evaluación a distancia y podría reducir el número de visitas hospitalarias. Los objetivos del estudio han sido evaluar la fiabilidad técnica y la seguridad clínica del sistema Home Monitoring™ (HM, Biotronik GmbH, Alemania). Hemos evaluado a 162 pacientes portadores de marcapasos (115), DAI (44) y DAI-TRC (3), durante un seguimiento medio de 303 ± 244 días. Se comparó ...
Tópico(s): ECG Monitoring and Analysis
2009 - Elsevier BV | Revista Española de Cardiología
Joaquín Osca, María José Sancho Tello, Josep Navarro, Óscar Cano, Rafael Raso, José Enrique Castro, José Olagüe, Antonio Salvador,
In recent years, physicians have experienced a huge increase in workload associated with cardiac devices. Remote monitoring enables these devices to be monitored at a distance and could reduce the number of hospital visits. The aim of this study was to assess the technical reliability and clinical safety of the Home MonitoringTM remote monitoring system (Biotronik GmbH, Germany).The study included 162 patients: 115 with pacemakers, 44 with implantable cardioverter-defibrillators (ICDs) and three with ...
Tópico(s): Quality and Safety in Healthcare
2009 - Elsevier BV | Revista Española de Cardiología (English Edition)
Amadeo Benavent‐Climent, Enrique Castro, Antolino Gallego,
This paper ascertains that Acoustic Emission (AE) monitoring is very effective for assessing the damage of reinforced concrete wide beam-column connections subjected to earthquake-type loadings. A cyclic test is conducted on an exterior connection until its failure. The experimental results show a strong correlation between the hysteretic strain energy and the AE energy histories. For this reason, a tentative formula is proposed, to predict the level of damage and the closeness to failure of the ...
Tópico(s): Concrete Corrosion and Durability
2009 - SAGE Publishing | Structural Health Monitoring
Milan Milenković, Enrique Castro-Leon, James R. Blakley,
Power efficiency is a major concern in operating cloud data centers. It affects operational costs and return on investment, with a profound impact on the environment. Current data center operating environments, such as management consoles and cloud control software, tend to optimize for performance and service level agreements and ignore power implications when evaluating workload scheduling choices. We believe that power should be elevated to the first-order consideration in data-center management ...
Tópico(s): IoT and Edge/Fog Computing
2009 - Springer Science+Business Media | Lecture notes in computer science
Jesús Pintor, Magdalena Torres, Enrique Castro, M. Teresa Miras‐Portugal,
Diadenosine tetraphosphate (Ap 4 A) a dinucleotide, which is stored in secretory granules, presents two types of high affinity binding sites in chromaffin cells. A K d value of 8 ± 0.65 × 10 −11 m and B max value of 5420 ± 450 sites per cell were obtained for the high affinity binding site. A K d value of 5.6 ± 0.53 × 10 −9 m and a B max value close to 70,000 sites per cell were obtained for the second binding site with high affinity. The diadenosine polyphosphates, Ap 3 A, Ap 4 A, Ap 5 A and Ap 6 A, displaced [ ...
Tópico(s): Oral and gingival health research
1991 - Wiley | British Journal of Pharmacology
Mauricio Cabrera, Enrique A. Castro, Mirtha Salas, José G. Santos, Patricia Sepulveda,
... aminolysis of O-ethyl S-aryl dithiocarbonatesMauricio Cabrera, Enrique A. Castro, Mirtha Salas, Jose G. Santos, and Patricia SepulvedaCite ...
Tópico(s): DNA and Nucleic Acid Chemistry
1991 - American Chemical Society | The Journal of Organic Chemistry
I. Herrero, Enrique Castro, Marı́a Teresa Miras-Portugal, José Sánchez‐Prieto,
The Ca2+-dependent release of glutamate induced by 4-aminopyridine (4-AP) in rat cerebral cortical synaptosomes was reduced by removal of bovine serum albumin (BSA) from the incubation medium. The decrease in the glutamate release in the absence of BSA was consistent with a reduction in the rise in cytosolic free [Ca2+] after depolarization with 4-AP. Contrarily, neither the glutamate release nor the elevation in cytosolic free [Ca2+] after depolarization with 30 mM KCl was altered by the removal of ...
Tópico(s): Ion channel regulation and function
1991 - Elsevier BV | Neuroscience Letters
Ana I. Jiménez, Enrique Castro, Esmerilda G. Delicado, Marı́a Teresa Miras-Portugal,
Abstract In this study, we show specific intracellular responses evoked by the stimulation of astrocytes with the P 1 , P 5 ‐di(adenosine‐5′)pentaphosphate, Ap 5 A. The stimulation of astrocytes with micromolar concentrations of the dinucleotide elicited rapid increases in intracellular calcium concentration ([Ca 2+ ] i ), showing an EC 50 value of 15.27 ± 0.61 µ m . Moreover, the stimulation of cells with nanomolar concentrations of Ap 5 A, unable to induce calcium responses, increased the phosphorylated forms ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2002 - Wiley | Journal of Neurochemistry
Miguel Díaz‐Hernández, Jesús Pintor, Enrique Castro, Marı́a Teresa Miras-Portugal,
The combination of immunological and microfluorimetric techniques has permitted the identification and analysis of the Ca2+ influx responses in single rat midbrain cholinergic terminals. These terminals represent 22% of the total synaptosomal population and about 63% of them responded to nucleotides by a Ca2+ influx. The nucleotide response distribution in cholinergic synaptic terminals is as follows; 22.4% to diadenosine pentaphosphate (Ap5A), 24.7% to adenosine 5′-triphosphate (ATP) and 16.3% to ...
Tópico(s): Receptor Mechanisms and Signaling
2002 - Elsevier BV | Neuropharmacology
Produção Nacional
Revisado por pares
Ceila María Sant’Ana Malaque, Jaime Enrique CASTRO-VALENCIA, João Luiz Costa Cardoso, Francisco Oscar de Siqueira França, Kátia Cristina Barbaro, Fan Hui Wen,
A retrospective study analysed 359 proven or presume cases of loxoscelism seen at the Hospital Vital Brazil, Instituto Butantan, São Paulo, Brazil, between 1985 and 1996. The spider was identified in 14%. The bites occurred predominantly in the urban areas (73%) between September and February. Patients > 14 years were commonest inflicted (92%) and 41% were bitten while getting dressed. Only 11% sought medical care within the first 12 hours post bite. Cutaneous loxoscelism was the commonest form presenting ( ...
Tópico(s): Rabies epidemiology and control
2002 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
Carmelo Millán, Enrique Castro, Magdalena Torres, Ryuichi Shigemoto, José Sánchez‐Prieto,
The modulation of calcium channels by metabotropic glutamate receptors (mGluRs) is a key event in the fine-tuning of neurotransmitter release. Here we report that, in cerebrocortical nerve terminals of adult rats, the inhibition of glutamate release is mediated by mGluR7. In this preparation, the major component of glutamate release is supported by P/Q-type Ca2+ channels (72.7%). However, mGluR7 selectively reduced the release component that is associated with N-type Ca2+ channels (29.9%). Inhibition ...
Tópico(s): Ion channel regulation and function
2003 - Elsevier BV | Journal of Biological Chemistry
Enrique Castro, A. Tom, Marı́a Teresa Miras-Portugal, Lu�s M. Ros�rio,
Tópico(s): Ion channel regulation and function
1994 - Springer Science+Business Media | Pflügers Archiv - European Journal of Physiology
Juan José González de la Rosa, Antonio Moreno‐Muñoz, Antolino Gallego, Rosa Piotrkowski, Enrique Castro,
This paper deals with power-quality (PQ) event detection, classification and characterization using higher-order sliding cumulants (which are calculated over high-pass filtered signals to avoid the low-frequency 50-Hz sinusoid), whose maxima and minima are the coordinates of two-dimensional feature vectors. The classification strategy is based in competitive layers. We focus on the problem of differentiating two types of transients: short-duration (impulsive transients) and long-duration (oscillatory ...
Tópico(s): Electromagnetic Compatibility and Noise Suppression
2008 - Elsevier BV | Measurement