Barbara Bellei, Enrica Flori, Enzo Izzo, Vittoria Maresca, Mauro Picardo,
Glycogen synthase kinase 3β (GSK3β) is implicated in many biological events, including embryonic development, cell differentiation, apoptosis, and the insulin response. GSK3β also plays a key role in the Wnt/β-catenin pathway. The master regulator of the pigmentation microphthalmia-associated transcription factor (MITF) is a target for the Wnt pathway, however, to date, the regulatory role of GSK3β in the control of melanogenesis has not been elucidated. In this study, we evaluated the effect of inhibiting ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2008 - Elsevier BV | Cellular Signalling
B. Baggio, Alessandro Budakovic, Alberto Ferraro, S Checchetto, Giovanna Priante, Estella Musacchio, Enzo Manzato, Martina Zaninotto, M.C. Maresca,
To investigate the relationship between polyunsaturated fatty acid (PUFA) and bone metabolism in renal transplant patients, plasma phospholipid (PP) PUFA levels, biochemical markers of bone turnover and bone mineral density (BMD) were determined in 22 recipients of a first renal allograft at baseline and after a mean 24.4 month follow-up. A significant increase in PP n-3 PUFA content, in the [n-3 PUFA/ arachidonic acid] ratio and in BMD values was observed, as well as a close correlation between the ...
Tópico(s): Bone and Joint Diseases
2005 - Wolters Kluwer | Transplantation
Mauro Mazzei, Enzo Sottofattori, Mario Di Braccio, A. BALBI, Giuliana Leoncini, Enrica Buzzi, Marc Maresca,
Tópico(s): Chemical Synthesis and Analysis
1990 - Elsevier BV | European Journal of Medicinal Chemistry