... For these reasons, we were motivated to employ EPIK here for high-resolution imaging. The method was optimised to offer the highest possible in-plane resolution and slice coverage under the given imaging constraints: fixed TR/TE, FOV and acceleration factors for parallel imaging and partial Fourier techniques. The performance of EPIK was evaluated in direct comparison to the optimised ...
Tópico(s): Functional Brain Connectivity Studies
2017 - Public Library of Science | PLoS ONE
Fabian Küppers, Seong Dae Yun, N. Jon Shah,
... sampling of the k‐space center inherent to EPIK, enables a high effective temporal resolution. That is, for an eight‐slice breath‐hold experiment, a temporal sampling rate of eight reconstructed slices per 1.1 s. Results In comparison with repeated single‐echo SE, multi‐echo GE, and spectroscopy methods, the GE‐SE EPIK sequence shows good agreement in quantifying T 2 / ...
Tópico(s): Cardiac Imaging and Diagnostics
2022 - Wiley | Magnetic Resonance in Medicine
N. Momejian, Majdi Abou Najm, Ibrahim Alameddine, M. El‐Fadel,
... with mapped vulnerability predictions obtained through DRASTIC and EPIK. While field measurements demonstrated high levels of groundwater salinity depending on the density of urbanization, both vulnerability assessment methods exhibited a limited ability in capturing saltwater intrusion dynamics. In the three pilot areas, DRASTIC was only able to predict correctly between 8.3 and 55.6% of the salinity-based water quality ranges, while EPIK's predictions ranged between 11.7 and 77. ...
Tópico(s): Geophysical and Geoelectrical Methods
2018 - Elsevier BV | Environmental Impact Assessment Review
Jacqueline Bezençon, Matthias Wittwer, Brian Cutting, Martin Smieško, Bjoern Wagner, Manfred Kansy, Beat Ernst,
... methods. Moreover, the comparison with in silico results (Epik and Marvin) also showed high correlations (R2 = 0.92 and 0.94), further ...
Tópico(s): Chemical and Physical Properties in Aqueous Solutions
2013 - Elsevier BV | Journal of Pharmaceutical and Biomedical Analysis

Panagiotis A. Konstantinopoulos, Antonio González‐Martín, Felipe Melo Cruz, Michael Friedlander, Rosalind Glasspool, Domenica Lorusso, Christian Marth, Bradley J. Monk, Jae‐Weon Kim, Patsy Hinson, Olga Ajipa, Vincent Prêtre, Yu Han, Ursula A. Matulonis,
Patients with platinum-resistant or -refractory high-grade serous ovarian cancer (HGSOC) have a poor prognosis, and their management represents a substantial unmet medical need. Preclinical data and results from a phase Ib trial demonstrated the efficacy and tolerability of the combination of the α-specific phosphatidylinositol-3-kinase (PI3K) inhibitor alpelisib plus the poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor olaparib in platinum-resistant, non-
Tópico(s): Toxin Mechanisms and Immunotoxins
2022 - Future Medicine | Future Oncology
Ayan Banerjee, Payal Kamboj, Sarah N. Wyckoff, Bethany L. Sussman, Sandeep Gupta, Varina L. Boerwinkle,
... SOZ localization algorithm (EPIK) for children with DRE.EPIK is developed in a phased approach, where fMRI noise-related biomarkers are used through high-fidelity image processing techniques to eliminate noise ICs. Then, the SOZ markers are used through a maximum likelihood-based classifier to determine SOZ localizing ICs. The performance of EPIK was evaluated on a unique pediatric DRE dataset ( ...
Tópico(s): Epilepsy research and treatment
2023 - Frontiers Media | Frontiers in Neuroimaging
Anastasia Vogelbacher, Nerantzis Kazakis, Konstantinos Voudouris, Steffen Bold,
... been obtained, including the worldwide application of the EPIK method. The hazard map has been developed for the implementation of risk assessment. The resulting vulnerability map was divided into four classes and showed especially high to very high vulnerability. The subsequent hazard assessment ... consists of 13% of very high, 48% of high, 36% of moderate and 4% of low risk of contamination. According to the literature overview, the EPIK method was mostly used in combination with other ...
Tópico(s): Groundwater and Watershed Analysis
2019 - Multidisciplinary Digital Publishing Institute | Environments
György Tibor Balogh, Benjámin Gyarmati, Balázs Nagy, László Molnár, György M. Keserü,
... five different p K a prediction tools (ACDpKa, Epik, Marvin pKa, Pallas pKa, and VCCpKa) was investigated on the 248‐membered Gold Standard dataset. We found VCC as the most predictive, high throughput p K a predictor. However since VCC ...
Tópico(s): Chemistry and Chemical Engineering
2009 - Wiley | QSAR & Combinatorial Science
Francesca Biava, Mauro Consonni, Vincenzo Francani, Paola Gattinoni, Laura Scesi,
... criterion and geomorphological-structural criterion (based on the EPIK method). The results show that with a chronological approach protection zones are located along the main flow directions, corresponding to the areas surrounding wells and springs with high hydraulic conductivity values (faults and thrusts) within the satured zone. On the contrary, the geomorphological method has found some important protection zones also quite far from wells and springs, in areas characterized by quick infiltration processes. The protection zones delineated with the stochastic method were finally intersected by the vulnerability map obtained with the EPIK method, to take into account both filtration and ...
Tópico(s): Groundwater flow and contamination studies
2014 - Scientific Research Publishing | Journal of Water Resource and Protection
Seong Dae Yun, Patricia Pais‐Roldán, Nicola Palomero‐Gallagher, N. Jon Shah,
... resting‐state networks was demonstrated. Furthermore, TR‐external EPIK enabled the identification of various resting‐state networks distributed throughout the brain from a single fMRI session, with mapping fidelity onto the grey matter at 7T. The high‐resolution functional image further revealed mesoscale anatomical structures, ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2022 - Wiley | Human Brain Mapping
... kg). Also, Dragomir 113021400, Cadenz Red 114151975 and Epik DE348025783 are characterized by a high degree of consolidation (Kс = 0.323 … 0.379) ...
Tópico(s): Genetic and phenotypic traits in livestock
2022 - | Animal Breeding and Genetics

Débora Lara Pereira, Paulo Galvão, Thiago Nogueira Lucon, Maria Augusta Gonçalves Fujaco,
... water resource management and land use planning, the EPIK method was adapted to the hydrogeologic reality of the São Miguel watershed, considering both local vegetation and the current Brazilian speleological heritage protection legislation. Results revealed that 52% of the area has moderate vulnerability and 7% high vulnerability, this latter one concentrated in areas close ...
Tópico(s): Groundwater and Isotope Geochemistry
2018 - Elsevier BV | Journal of South American Earth Sciences
M. Polemio, D. Casarano, P. P. Limoni,
... phenomena, is located. Several methods (GOD, DRASTIC, SINTACS, EPIK, PI, and COP) for the assessment of the intrinsic vulnerability (Iv) were selected and applied to an Apulian test site, for which a complete data set was set up. The intrinsic vulnerability maps, produced using a GIS approach, show vulnerability from low to very high. The maximum vulnerability is always due to karstic ... method is useful for mapping large areas with high vulnerability contrasts. DRASTIC and SINTACS are "any-type aquifer" methods that have some limitations in applications to karstic aquifers, especially in the case of DRASTIC. EPIK, PI, and COP, which were designed to be ...
Tópico(s): earthquake and tectonic studies
2009 - Copernicus Publications | Natural hazards and earth system sciences
Muheeb Awawdeh, Awad Nawafleh,
... was to demonstrate the combined use of the EPIK and geographical information system (GIS) as an effective method for groundwater pollution risk assessment. Using this method of investigation, the pollution susceptibility map classifies 3% of the study area as having low pollution susceptibility, 63% as having moderate pollution susceptibility, 33% as having high pollution susceptibility, and 1% as having very high ...
Tópico(s): Groundwater and Watershed Analysis
2008 - Jordan University of Science and Technology | Jordan Journal of Civil Engineering
... the Antalya Travertine Plateau based on DRASTIC, SINTACS, EPIK, COP and PI methods. Majority of the study area is covered by productive karstic aquifer, which is composed of travertine. Travertine includes typical karstic features such as dolines, springs and caves where groundwater of travertine aquifer is the sole source for irrigation. Areal extends of low, medium, high and very high vulnerability classes and their areal ...
Tópico(s): Data Quality and Management
1973 - Elsevier BV | Geoforum
Ayşenur Amil, Pınar Avcı, Ahmet Çil, Ayşe Muhammetoğlu, Naciye Nur Özyurt,
... the Antalya Travertine Plateau based on DRASTIC, SINTACS, EPIK, COP and PI methods. Majority of the study area is covered by productive karstic aquifer, which is composed of travertine. Travertine includes typical karstic features such as dolines, springs and caves where groundwater of travertine aquifer is the sole source for irrigation. Areal extends of low, medium, high and very high vulnerability classes and their areal ...
Tópico(s): Groundwater flow and contamination studies
2019 - Elsevier BV | Journal of Contaminant Hydrology
... recommended for the future. SINTACS method generates very high vulnerability zones with surface waters and aquifer interactions. GOD method could be adequate for vulnerability mapping in karstified carbonate aquifers at small–moderate scales, and EPIK method can be used for large scale. GOD ...
Tópico(s): Groundwater flow and contamination studies
2018 - IOP Publishing | IOP Conference Series Earth and Environmental Science
N. Jon Shah, Nuno André da Silva, Seong Dae Yun,
... have been widely used due to their relatively high imaging speed. However, when used with increasing spatial resolution, single‐shot EPI methods often show limitations in whole‐brain coverage for multi‐contrast applications. To overcome this limitation, this work employs a new version of EPI with keyhole (EPIK) to provide five echoes: two with GEs, two ...
Tópico(s): MRI in cancer diagnosis
2019 - Wiley | Human Brain Mapping
Panagiotis A. Konstantinopoulos, Jae‐Weon Kim, Gilles Freyer, Jung-Yun Lee, Lydia Gaba, Rachel N. Grisham, N. Colombo, Xiaohua Wu, Jalid Sehouli, Felipe Melo Cruz, David Cibula, Bradley J. Monk, Gitte‐Bettina Nyvang, Michael Friedlander, Domenica Lorusso, Els Van Nieuwenhuysen, Rosalind Glasspool, Christian Marth, Patsy Hinson, Monica Zuradelli, Craig Wang, Faye Su, Michelle Miller, Ursula A. Matulonis, Antonio González‐Martín,
Tópico(s): BRCA gene mutations in cancer
2024 - Elsevier BV | Gynecologic Oncology
Nataša Ravbar, Nico Goldscheider,
... tracer tests. The test site is characterised by high water table fluctuations, manifested in intermittent lakes and variable drainage divides. A first multi-tracer test (two injections) allowed subdivision of the catchment into zones of different degrees of contribution (‘inner zone’ and ‘outer zone’). For vulnerability mapping, only methods that consider the specific nature of karst aquifers such as heterogeneity and duality of infiltration processes, were selected: EPIK, PI, the ‘Simplified Method’ and the ‘Slovene Approach’. ...
Tópico(s): Groundwater and Isotope Geochemistry
2008 - Springer Science+Business Media | Hydrogeology Journal
Rita G. Nunes, Peter Jezzard, Timothy E.J. Behrens, Stuart Clare,
... of tracking algorithms. To combat partial volume effects, high‐resolution multishot techniques can be used but, being more sensitive to motion, require phase correction to obtain artifact‐free images. While separately acquiring 2D navigator echoes is an effective approach, it is not very efficient as the navigators do not contribute signal to the final image. Here a self‐navigated interleaved echo planar imaging (EPI) sequence based on EPI with keyhole (EPIK) is proposed. The refocusing reconstruction method is successfully ...
Tópico(s): Fetal and Pediatric Neurological Disorders
2005 - Wiley | Magnetic Resonance in Medicine
... of B in W2B given by A. P. Epik.Insulating properties of BN for W leads dropped ...
Tópico(s): Metal and Thin Film Mechanics
1970 - Ceramic Society of Japan | Journal of the Ceramic Association Japan
Ruijuan Chen, Xiaohua Wan, İlkay Altıntaş, Jianwu Wang, Daniel Crawl, Sébastien Phan, Albert F. Lawrence, Mark H. Ellisman,
... a workflow for Electron Tomography Programs in Kepler (EPiK). This EPiKworkflow embeds the tracking process of IMOD, ... tested the three dimensional (3D) reconstruction process using EPiK on ET data. EPiK can be a potential toolkit for biology researchers ...
Tópico(s): Particle Detector Development and Performance
2014 - Elsevier BV | Procedia Computer Science
... talk.go.kr//talk/talk/talkhme/main.jsp7. EPIK stands for English Program in Korea. For more information, see http://www.epik.go.kr/
Tópico(s): Subtitles and Audiovisual Media
2014 - Routledge | Language Culture and Curriculum
Priyanka Sharma, Azeez Farooki, Peter A. Fasching, Sherene Loi, Kevin Peterson, Aleix Prat, Debu Tripathy, Binghe Xu, Denise A. Yardley, D. Mills, G. Klauss, Connie Wong, Fabrice André,
... phase I/II trial, which included TNBC patients. EPIK-B3 is a phase III trial in 3 ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2020 - Elsevier BV | Annals of Oncology
... izvira Korentan pri Postojni pa smo uporabili metodo EPIK, ki je bila že večkrat uspešno preizkušena na ... area of the Korentan spring near Postojna the EPIK method was used. In this method, which was ...
Tópico(s): Groundwater and Isotope Geochemistry
2016 - | Acta Carsologica
... figures’ speech [. . .] can be even in the Middle High German epic despite being strongly shaped by rhyme and meter’ [wie differenziert [End Page 173] die individuelle Figurensprache bereits in der mittelhochdeutschen Epik trotz ihrer Überformung durch Reim und Metrik sein ...
Tópico(s): Medieval Literature and History
2021 - Scriptoriun Press | Arthuriana
Daphne Ezer, Victoria Moignard, Berthold Göttgens, Boris Adryan,
... of cells (Estimation of Parameter changes in Kinetics, EPiK). We applied these methods to hematopoiesis, including a ...
Tópico(s): Zebrafish Biomedical Research Applications
2016 - Public Library of Science | PLoS Computational Biology
... Entstehungsgeschichte dreier Gedichte Conrad Ferdinand Meyers. Neue deutsche Epik. By Heinrich Maiworm. Ordnung und Recht in der ...
1971 - Wiley | German Life and Letters
E. Steiakakis, D. Vavadakis, Ourania Mourkakou,
... on the application of three index-based methods (EPIK, PRESK and DRISTPI). The protection zones for the ...
Tópico(s): Groundwater and Isotope Geochemistry
2023 - Multidisciplinary Digital Publishing Institute | Water