Cameron Kia, Christopher L. Antonacci, Ian J. Wellington, Heeren Makanji, Sean Esmende,
The use of interbody implants for spinal fusion has been steadily increasing to avoid the risks of complications and donor site morbidity when using autologous bone. Understanding the pros and cons of various implant designs can assist the surgeon in choosing the ideal interbody for each individual patient. The goal of these interbody cages is to promote a surface area for bony ingrowth while having the biomechanical properties to support the axial skeleton. Currently, the majority of interbody ...
Tópico(s): Orthopaedic implants and arthroplasty
2022 - Multidisciplinary Digital Publishing Institute | Bioengineering
Alan H. Daniels, Melanie Arthur, Sean Esmende, Hari T. Vigneswaran, Mark A. Palumbo,
In Brief Study Design. Retrospective database analysis. Objective. To examine the incidence of hospitalization, treatment, and cost of caring for patients with axis (C2) fractures. Summary of Background Data. The incidence of C2 fractures in the elderly seems to be increasing, however, a comprehensive analysis of the incidence, treatment, and cost of treating C2 fractures has not been previously reported. Methods. The Nationwide Inpatient Sample from 2000 to 2010 was used to identify patients with ...
Tópico(s): Hip and Femur Fractures
2014 - Lippincott Williams & Wilkins | Spine
Eugene Farng, Alfonso R. Urdaneta, David Barba, Sean Esmende, David R. McAllister,
Recent endeavors in tissue engineering have attempted to identify the optimal parameters to create an artificial ligament. Both mechanical and biochemical stimulation have been used by others to independently modulate growth and differentiation, although few studies have explored their interactions. We applied previously described fabrication techniques to create a highly porous (90%–95% porosity, 212–300 μm), 3-D, bioabsorbable polymer scaffold (polycaprolactone). Scaffolds were coated with bovine ...
Tópico(s): Knee injuries and reconstruction techniques
2008 - Lippincott Williams & Wilkins | Clinical Orthopaedics and Related Research
Frank A. Petrigliano, Christopher S. English, David Barba, Sean Esmende, Benjamin M. Wu, David R. McAllister,
The objectives of this investigation were (1) to characterize the growth factor release profile of a basic fibroblast growth factor (bFGF)-coated three-dimensional (3D) polymer scaffold under static and cyclically strained conditions, and (2) to delineate the individual and collective contributions of locally released bFGF and mechanical strain on cellular morphology and gene expression in this 3D system. Scaffolds were treated with I(125)-bFGF and subjected to mechanical strain or maintained in a static ...
Tópico(s): Tendon Structure and Treatment
2007 - Mary Ann Liebert, Inc. | Tissue Engineering
Ian J. Wellington, Cameron Kia, Ergin Coskun, Barrett B. Torre, Christopher L. Antonacci, Michael R. Mancini, John P. Connors, Sean Esmende, Heeren Makanji,
While spinal disc pathology has traditionally been treated using fusion-based procedures, recent interest in motion-preserving disc arthroplasties has grown. Traditional spinal fusion is associated with loss of motion, alteration of native spine kinematics, and increased risks of adjacent segment disease. The motion conferred by disc arthroplasty is believed to combat these complications. While the first implant designs resulted in poor patient outcomes, recent advances in implant design and technology ...
Tópico(s): Spinal Fractures and Fixation Techniques
2022 - Multidisciplinary Digital Publishing Institute | Bioengineering
Sean Esmende, Alan H. Daniels, David Paller, Sarath Koruprolu, Mark A. Palumbo, Joseph J. Crisco,
Background context The pendulum testing system is capable of applying physiologic compressive loads without constraining the motion of functional spinal units (FSUs). The number of cycles to equilibrium observed under pendulum testing is a measure of the energy absorbed by the FSU. Objective To examine the dynamic bending stiffness and energy absorption of the cervical spine, with and without implanted cervical total disc replacement (TDR) under simulated physiologic motion. Study design A biomechanical ...
Tópico(s): Spinal Fractures and Fixation Techniques
2014 - Elsevier BV | The Spine Journal
Sean Esmende, Alan H. Daniels, Mark A. Palumbo,
A 65-year-old man with a history of metastatic squamous cell carcinoma of the tongue underwent a percutaneous kyphoplasty at an outside hospital for a painful T9 metastatic compression fracture. Immediately after the procedure, the patient developed saddle anesthesia and progressive bilateral lower extremity numbness and weakness. He was then transferred to our hospital for further care. Computed tomography and magnetic resonance imaging revealed kyphoplasty cement within the T9 vertebral body (Fig. ...
Tópico(s): Spinal Hematomas and Complications
2013 - Elsevier BV | The Spine Journal
Jacob Silver, Colin Pavano, Nicholas Bellas, Cory Hewitt, Barrett B. Torre, Mathew Solomito, Regina O. Kostyun, Sean Esmende,
Recently, there has been increasing legalization of marijuana within the United States, however data are mixed with respect to its efficacy in treating acute pain. Our goal was to identify a difference in opioid utilization in patients with known cannabis use before anterior cervical discectomy and fusion (ACDF) compared with those that report no cannabis use.This study was a retrospective case-control design using PearlDiver. Patients who underwent a single level ACDF between January 2010 and October ...
Tópico(s): Opioid Use Disorder Treatment
2023 - Elsevier BV | North American Spine Society Journal (NASSJ)
Purpose: Improper pedicle screw placement can lead to increased complications and the need for revision surgery. The purpose of this article is to review the history of robotic assistance in spine surgery, along with the current data on its clinical outcomes, potential advantages, and economics on practice. Methods: Review of the literature. Results: A review of the current literature demonstrated that intrapedicular accuracy has shown to be either superior or equivalent to a free-hand technique. ...
Tópico(s): Medical Imaging and Analysis
2020 - Lippincott Williams & Wilkins | Techniques in Orthopaedics
Gal Barkay, Matthew J. Solomito, Regina O. Kostyun, Sean Esmende, Heeren Makanji,
With the increased use of cannabis in the US, there is a significant need to understand the medical complications associated with its use in relationship to a surgical population. Cannabis has mainly been studied with respect to its qualities of pain treatment, yet few studies have investigated post-surgical complications associated with its use. Therefore, the purpose of this study was to explore the effect of cannabis use on complications in spine surgery, and compare these complications rates ...
Tópico(s): Forensic Toxicology and Drug Analysis
2023 - Elsevier BV | North American Spine Society Journal (NASSJ)
Sean Esmende, Matthew J. Solomito, Jesse Eisler, Kevin J. Finkel, Pranjali Kainkaryam, Carla L. Maffeo-Mitchell,
Anterior lumbar interbody fusion (ALIF) is a well-established technique to address numerous pathological conditions of the spine and to restore sagittal spine balance. Improving patient comfort and reducing opioid consumption following lumbar fusions is a significant goal for spine surgeons. Therefore, there is a growing need to explore multimodal options for pain management post-surgery.Determine the effectiveness of combined transversus abdominis plane (TAP) and rectus sheath (RS) blocks in those ...
Tópico(s): Musculoskeletal pain and rehabilitation
2022 - Elsevier BV | The Spine Journal
Jason O. Toy, Sean Esmende, Chinedu Nwasike, Joon Y. Lee, William F. Donaldson,
Adjacent segment disease can be a clinically significant complication following lumbar spinal arthrodesis. This disease is traditionally addressed surgically via a posterior approach, which can be associated with significant morbidity and complication. In recent years, the minimally invasive lateral approach has evolved as an effective surgical option for arthrodesis in the lumbar spine. We detail our use of this approach as an alternative treatment for adjacent segment disease, as it allows for ...
Tópico(s): Cervical and Thoracic Myelopathy
2017 - Elsevier BV | Operative Techniques in Orthopaedics
Christopher L. Antonacci, Francine Zeng, Casey Jackson, Ian J. Wellington, Seema Patel, Sean Esmende,
Adjacent segment disease (ASD) is a late complication of lumbar fusion characterized by persistent symptoms correlating to radiographic changes in the levels immediately above or below the prior fusion. Lateral interbody fusion (LIF) through a direct lateral approach is a minimally invasive and effective surgical treatment for ASD. Biomechanically, LIF for ASD provides significantly decreased motion in multiple planes. While hardware failure and injury to the lumbar plexus are potential complications, ...
Tópico(s): Nail Diseases and Treatments
2024 - AME Publishing Company | Journal of Spine Surgery
Heeren Makanji, Matthew J. Solomito, Regina O. Kostyun, Sean Esmende,
Study Design: Retrospective database. Objective: The purpose of this study was to understand how a mental health disorder, specifically anxiety and depression, influences a patient’s postoperative opioid needs following single-level lumbar spine fusion. Summary of Background Data: Patients with spine pathology commonly demonstrate symptoms of an active psychiatric disorder. Mental health significantly influences how a patient perceives pain and a patient’s opioid pain control needs after surgery. ...
Tópico(s): Musculoskeletal pain and rehabilitation
2023 - Lippincott Williams & Wilkins | Clinical Spine Surgery A Spine Publication
Heeren Makanji, Matthew J. Solomito, Regina O. Kostyun, Sean Esmende,
Patients with spine pathology demonstrate an above average rate of active psychiatric disorders, which can influence their recovery. This study was designed to understand how mental health diagnoses (ie, anxiety and depression) influence a patient's postoperative need for opioids after a single level cervical spine fusion. The PearlDiver database was used to identify patients. Patients were placed into one of four groups: those with a diagnosis of depression, those with a diagnosis of anxiety, those ...
Tópico(s): Pain Management and Opioid Use
2023 - Slack Incorporated (United States) | Orthopedics
M. Gleeson, Matthew J. Solomito, Regina O. Kostyun, Sean Esmende, Heeren Makanji,
Background Previous research has shown that underweight patients may be at a greater risk of experiencing postsurgical complications. The purpose of this study was to investigate the association between body mass index (BMI) and postoperative complications following single-level anterior lumbar fusion (ALF). Methods All single-level elective ALF procedures performed between 2010 and 2020 were identified in the PearlDiver Mariner Database. Patients were separated into 6 groups based on the World Health Organization ...
Tópico(s): Pelvic and Acetabular Injuries
2023 - CIG Media Group | The International Journal of Spine Surgery
Heeren Makanji, Matthew J. Solomito, Carla L. Maffeo-Mitchell, Sean Esmende, Kevin J. Finkel,
Retrospective.The purpose of this study was to determine the utility of the erector spinae plane regional anesthesia (ESP) block in reducing opioid medication usage and postanesthesia care unit length of stay (PACU-LOS) for patients undergoing either a posterior or transforaminal lumbar interbody fusions (PLIF/TLIF).Posterior lumbar spine fusion is a common surgical procedure typically associated with significant postoperative pain. Poorly controlled postoperative pain can lead to a number of poor ...
Tópico(s): Spine and Intervertebral Disc Pathology
2022 - Lippincott Williams & Wilkins | Clinical Spine Surgery A Spine Publication
Larry V. Lee, Sean Esmende, Christopher T. Born,
Total knee arthroplasty, although a very successful surgery, can present the patient with several potential complications, including the risk for periprosthetic fractures. Complications involving periprosthetic fractures after total knee arthroplasty can present a complex clinical scenario for orthopedic surgeons. To date, adequate literature exists to guide surgeons in approaching most periprosthetic fractures; however, standard operating procedure can fall short when confronted with more complex ...
Tópico(s): Orthopedic Infections and Treatments
2016 - Slack Incorporated (United States) | Orthopedics
Alan H. Daniels, Sean Esmende, Mark A. Palumbo,
The incidence of C2 fractures in the elderly appears to be increasing. However, a comprehensive analysis of the incidence, treatment and cost of treating C2 fractures has not been previously reported.
Tópico(s): Medical Imaging and Analysis
2014 - Elsevier BV | The Spine Journal
FigureThroughout the summer season in Naragansett, Rhode Island various rock sculptures are molded from the shoreline. The “Imagery” section of Spine is devoted to the artistic and imaginative qualities of our readers. Spine invites you to submit your drawings, illustrations, or photographs, along with appropriate explanatory information, for consideration of publication within this section. Please forward electronic images via e-mail to: [email protected].
Tópico(s): Metallurgy and Cultural Artifacts
2014 - Lippincott Williams & Wilkins | Spine
Sean Esmende, Frank A. Petrigliano, David Barba, Bo Wu, David R. McAllister,
Rupture of the anterior cruciate ligament (ACL) is one of the most common ligament injuries of the knee. Current ACL surgical strategies consist of using a local autograft or allograft to replace the native ligament. Decreased range of motion and weakness has been commonly associated with autografts. Allografts are associated with immunogenic rejection and a lack of available donors. Previous studies have shown that human bone marrow stromal cells (BMSCs) can be stimulated toward a fibroblast-like ...
Tópico(s): Bone Tissue Engineering Materials
2007 - SAGE Publishing | Journal of Investigative Medicine
David Barba, Victor Sun, Sean Esmende, Frank A. Petrigliano, Daniel T. Kamei, David R. McAllister, Benjamin M. Wu,
The anterior cruciate ligament is a commonly injured ligament of the knee in which ligament reconstruction with a graft is necessary due to its limited healing capacity. With limitations on the existing graft alternatives, we aim to engineer a ligament using a donor9s bone marrow stromal cells (BMSCs). Recently, our laboratory reported synergism between biomechanical and biochemical stimulation (bFGF) resulting in up-regulation of gene expression of stress-resistant collagen I and stress-responsive ...
Tópico(s): Silk-based biomaterials and applications
2007 - SAGE Publishing | Journal of Investigative Medicine