R. B. Solari, Estéban Sáez, I. D'APOLLO, Alain Bellet,
Tópico(s): Advanced Control Systems Optimization
1982 - Taylor & Francis | Chemical Engineering Communications
Alejandra Valladares, Sahar Ahangari, Thomas Beyer, Ronald Boellaard, Zacharias Chalampalakis, Claude Comtat, Laura DalToso, Adam E. Hansen, Michel Koole, Jane E. Mackewn, Paul Marsden, Johan Nuyts, Francesco Padormo, Ronald Peeters, S Poth, Esteban Solari, Ivo Rausch,
Quality control (QC) of medical imaging devices is essential to ensure their proper function and to gain accurate and quantitative results. Therefore, several international bodies have published QC guidelines and recommendations for a wide range of imaging modalities to ensure adequate performance of the systems. Hybrid imaging systems such as positron emission tomography / computed tomography (PET/CT) or PET/ magnetic resonance imaging (PET/MRI), in particular, present additional challenges caused by ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2019 - Frontiers Media | Frontiers in Physics
Nicolò Capobianco, Ludovic Sibille, Maythinee Chantadisai, Andrei Gafita, Thomas Langbein, Guenther Platsch, Esteban Solari, Vijay Shah, Bruce Spottiswoode, Matthias Eiber, Wolfgang Weber, Nassir Navab, Stephan G. Nekolla,
In PSMA-ligand PET/CT imaging, standardized evaluation frameworks and image-derived parameters are increasingly used to support prostate cancer staging. Clinical applicability remains challenging wherever manual measurements of numerous suspected lesions are required. Deep learning methods are promising for automated image analysis, typically requiring extensive expert-annotated image datasets to reach sufficient accuracy. We developed a deep learning method to support image-based staging, investigating ...
Tópico(s): Medical Imaging Techniques and Applications
2021 - Springer Science+Business Media | European Journal of Nuclear Medicine and Molecular Imaging
Esteban Solari, Andrei Gafita, Sylvia Schachoff, Borjana Bogdanović, Alberto Villagrán Asiares, Thomas Amiel, Hui Wang, Isabel Rauscher, Dimitris Visvikis, Tobias Maurer, Kristina Schwamborn, Mona Mustafa, Wolfgang Weber, Nassir Navab, Matthias Eiber, Mathieu Hatt, Stephan G. Nekolla,
To evaluate the performance of combined PET and multiparametric MRI (mpMRI) radiomics for the group-wise prediction of postsurgical Gleason scores (psGSs) in primary prostate cancer (PCa) patients. Patients with PCa, who underwent [68 Ga]Ga-PSMA-11 PET/MRI followed by radical prostatectomy, were included in this retrospective analysis (n = 101). Patients were grouped by psGS in three categories: ISUP grades 1-3, ISUP grade 4, and ISUP grade 5. mpMRI images included T1-weighted, T2-weighted, and apparent ...
Tópico(s): Advanced X-ray and CT Imaging
2021 - Springer Science+Business Media | European Journal of Nuclear Medicine and Molecular Imaging
Borjana Bogdanović, Esteban Solari, Alberto Villagrán Asiares, Lachlan McIntosh, Sandra van Marwick, Sylvia Schachoff, Stephan G. Nekolla,
When this article was written, it coincided with the 11th anniversary of the installation of our PET/MR device in Munich. In fact, this was the first fully integrated device to be in clinical use. During this time, we have observed many interesting behaviors, to put it kindly. However, it is more critical that in this process, our understanding of the system also improved - including the advantages and limitations from a technical, logistical, and medical perspective. The last decade of PET/MRI research ...
Tópico(s): Advanced MRI Techniques and Applications
2021 - Elsevier BV | Seminars in Nuclear Medicine
Carezza Botto‐Mahan, Antonella Bacigalupo, Juana P. Correa, Esteban Oda, Aldo Solari,
Tópico(s): Helminth infection and control
2011 - Elsevier BV | Acta Tropica
Esteban Oda, Aldo Solari, Carezza Botto‐Mahan,
Abstract Several reports have described host species diversity and identity as the most important factors influencing disease risk, producing either dilution or amplification of the pathogen in a host community. Triatomine vectors, mammals and the protozoan Trypanosoma cruzi (Trypanosomatida: Trypanosomatidae) Chagas are involved in the wild cycle of C hagas disease, in which infection of mammals occurs by contamination of mucous membranes or skin abrasions with insect‐infected faeces. We examined ...
Tópico(s): Parasites and Host Interactions
2014 - Wiley | Medical and Veterinary Entomology
Daniela Estay-Olea, Juana P. Correa, Sophie de Bona, Antonella Bacigalupo, Nicol Quiroga, Esteban San Juan, Aldo Solari, Carezza Botto‐Mahan,
Hematophagous insects exhibit complex behaviour when searching for blood-meals, responding to several host stimuli. The hematophagous insect Mepraia spinolai is a wild vector of Trypanosoma cruzi, causative agent of Chagas disease in humans, in the semiarid-Mediterranean ecosystem of Chile. In this study, we evaluated the association between the approaching behaviour to a human host, with T. cruzi infection status and nutritional condition of M. spinolai. To this end, we captured 501 individuals ...
Tópico(s): Research on Leishmaniasis Studies
2020 - Elsevier BV | Acta Tropica
Alberto Villagrán Asiares, Teresa Vitadello, Borjana Bogdanović, Esteban Solari, Lachlan McIntosh, Sylvia Schachoff, Tareq Ibrahim, Stephan G. Nekolla,
This work investigated the impact of different cardiac gating methods on the assessment of cardiac function by FDG-PET in a cross-validation PET/MR study. MR- and PET-based left ventricular end-diastolic, end-systolic volumes, and ejection fraction (EDV, ESV, and EF) were delineated in 30 patients with a PET/MR examination. Cardiac PET imaging was performed using three ECG gating methods: fixed number of gates per beat (STD), STD with a beat acceptance window (STD-BR), and fixed gate duration (FW). ...
Tópico(s): Advanced MRI Techniques and Applications
2022 - Springer Science+Business Media | Journal of Nuclear Cardiology
Marcelo Corti, Hernán G. Solari, Luis De Carolis, Olga Figueiras, Natalia Vittar, Esteban Maronna,
Malignant syphilis in a patient infected by human immunodeficiency virus.Case report and literature reviewMalignant syphilis is a rare form of secondary syphilis strongly associated with human immunodeficiency virus infection (HIV).This clinical form of the disease is characterized by atypical cutaneous ulcerative and disseminated lesions and systemic compromise that can delay the final diagnosis.There are only few reports in the medical literature about malignant lues in HIV-infected patients.Malignant ...
Tópico(s): Autoimmune and Inflammatory Disorders
2012 - SciELO | Revista chilena de infectología
M Gammel, Esteban Solari, Matthias Eiber, Isabel Rauscher, Stephan G. Nekolla,
PET/MRI is a relevant application field for prostate cancer management, offering advantages in early diagnosis, staging, and therapy planning. Despite drawbacks such as higher costs, longer acquisition time, and the need for skilled personnel, the technical integration of PET and MRI provides valuable information for detecting primary tumors, identifying metastases, and characterizing the disease, leading to more accurate staging and personalized treatment strategies. However, PET/MRI adoption has ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2023 - Elsevier BV | Seminars in Nuclear Medicine
Produção Nacional
Revisado por pares
José Ignácio Gonzalez Solari, Eduardo Cremonese Filippi–Chiela, Emily Salles Pilar, Vitória Brum da Silva Nunes, Esteban Alberto Gonzalez, Fabrício Figueiró, Cristiano Feijó Andrade, Fábio Klamt,
Abstract Background Chemotherapeutics can stimulate immune antitumor response by inducing immunogenic cell death (ICD), which is activated by Damage-Associated Molecular Patterns (DAMPs) like the exposure of calreticulin (CRT) on the cell surface, the release of ATP and the secretion of High Mobility Group Box 1 (HMGB1). Methods Here, we investigated the levels of ICD-associated DAMPs induced by chemotherapeutics commonly used in the clinical practice of non-small cell lung cancer (NSCLC) and the association ...
Tópico(s): Adenosine and Purinergic Signaling
2020 - BioMed Central | BMC Cancer
Juana P. Correa, Antonella Bacigalupo, Esteban Yefi-Quinteros, Gemma Rojo‐Martínez, Aldo Solari, Pedro E. Cattan, Carezza Botto‐Mahan,
We present a review on the natural infection by trypanosomatids of nonhuman vertebrates in Chile, aiming to synthesize and update the knowledge on the diversity of trypanosomatids infecting native and alien vertebrate species. To this end, we conducted a systematic review of literature records published from 1900 to April 2020 on four databases, focusing on the 21 genera of trypanosomatids and Chile. The methods and findings of our review have been based on the preferred reporting items for systematic ...
Tópico(s): Research on Leishmaniasis Studies
2020 - Multidisciplinary Digital Publishing Institute | Pathogens
Juana P. Correa, Antonella Bacigalupo, Francisco E. Fontúrbel, Esteban Oda, Pedro E. Cattan, Aldo Solari, Carezza Botto‐Mahan,
Tópico(s): Insect symbiosis and bacterial influences
2015 - Springer Science+Business Media | The Science of Nature
Valeria Solari, Lucia Borriello, Gianluca Turcatel, Hiroyuki Shimada, Richard Sposto, G. Esteban Fernández, Shahab Asgharzadeh, Edwin A. Yates, Jeremy E. Turnbull, Yves A. DeClerck,
Heparan sulfate proteoglycans (HSPG) play a critical role in the interaction of tumor cells and their microenvironment. HSPG activity is dictated by sulfation patterns controlled by sulfotransferases, which add sulfate groups, and sulfatases (Sulf), which remove 6-O-sulfates. Here, we report altered expression of these enzymes in human neuroblastoma cells with higher levels of Sulf-2 expression, a specific feature of MYCN-amplified cells (MYCN-A cells) that represent a particularly aggressive subclass. ...
Tópico(s): Neonatal Respiratory Health Research
2014 - American Association for Cancer Research | Cancer Research
Valeria Solari, Lucia Borriello, G. Esteban Fernández, Hiroyuki Shimada, Richard Sposto, Shahab Asgharzadeh, Edwin A. Yates, Jeremy E. Turnbull, Yves A. DeClerck,
... oncogenic function in human neuroblastoma. Citation Format: Valeria Solari, Lucia Borriello, G. Esteban Fernandez, Hiroyuki Shimada, Richard Sposto, Shahab Asgharzadeh, Edwin ...
Tópico(s): Signaling Pathways in Disease
2014 - American Association for Cancer Research | Cancer Research
Resumen: Este texto presenta la idea de vida que sostiene Zubiri, indaga qué es la vida de Dios según el mismo y, en fi n, reconstruye cuál es la teoría del signifi cado de los enunciados teológico-fi losófi cos que emergen de las ideas maduras de Zubiri, considerando también otras ideas fi losófi
Tópico(s): Philosophy and Phenomenology Studies
2014 - Pontifical Catholic University of Chile | Teología y vida
Enzo Solari, Esteban Vargas Abarzúa,
Tópico(s): Spanish Philosophy and Literature
2014 - Pontifical Catholic University of Chile | Teología y vida
Esther Vergara Causo, Arnaldo Jorge Condori Palomino, Fredy Dueñas Linares, Hilda Valdivia Nascimento, Esteban Barco Solari, Thony Abel Lazo Herrera,
La investigación se basa en las estrategias de marketing que deben emplear las mujeres Shipibo-Konibo en la venta de vestimentas con esencia Shipiba mediante las redes sociales: Facebook, Youtube, wordpress, Instagram, posicionándolas en el mercado online, en tiempos de la Covid-19. El estudio describe los impactos socioeconómicos que ha tenido la comunidad Shipiba en la implementación de estrategias de marketing para vender vestimentas oriundas de una cultura amazónica. El estudio utiliza una metodología ...
Tópico(s): Business, Innovation, and Economy
2021 - | Revista Científica Pakamuros
Adam E. Hansen, Alejandra Valladares, Thomas Beyer, Ronald Boellard, Zacharias Chalampalakis, Claude Comtat, Sarah Ahangari, Laura DalToso, Michel Koole, Jane E. Mackewn, P J Marsden, Johan Nuyts, Francesco Padormo, Ralf Peeters, S Poth, Esteban Solari, Ivo Rausch,
Tópico(s): Advanced Radiotherapy Techniques
2019 - Frontiers Media | Frontiers in Physiology
Alejandra Valladares, Claude Comtat, Zacharias Chalampalakis, Michel Koole, Johan Nuyts, Ronald Boellaard, Laura DalToso, Paul Marsden, Jane E. Mackewn, S Poth, Esteban Solari, Sahar Ahangari, A. Tybiaerg Hansen, Thomas Beyer, Ivo Rausch,
This work aims at collecting relevant information on QC procedures and PET quantification across a European PET/MRI network, including the assessment of variations of PET(/MR) quantification using NEMA image quality phantom scans.
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2019 - Schattauer Verlag | Nuklearmedizin - NuclearMedicine
Esteban Solari, Alberto Villagrán Asiares, Sylvia Kleinert, Coletta Kruschke, Alexander Winter, Borjana Bogdanović, Mona Mustafa, Wolfgang Weber, SG Nekolla,
Since more than a decade, respiratory gating is available on PET/CT systems to improve diagnostic accuracy by reducing motion blurring. However, this is contrasted by increased scan times and logistical overhead. Thus, we investigated whether an integration with continuous bed motion (CBM) scanning addresses these limitations.
Tópico(s): Advanced Radiotherapy Techniques
2019 - Schattauer Verlag | Nuklearmedizin - NuclearMedicine
G. Garcia Ortegon, Esteban Solari, Sandra van Marwick, T. Hekimsoy, Matthias Eiber, Wolfgang Weber, Stephan G. Nekolla,
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2024 - Elsevier BV | Physica Medica
H. Porger, T. Hekimsoy, Sandra van Marwick, A. Reinhardt, Esteban Solari, W. Weber, Stephan G. Nekolla,
Tópico(s): Atomic and Subatomic Physics Research
2024 - Elsevier BV | Physica Medica
Yao Guo, Esteban Solari, Jing Ni, Stephan G. Nekolla,
Tópico(s): Advanced MRI Techniques and Applications
2024 - Elsevier BV | Physica Medica
Alberto Villagrán Asiares, Teresa Vitadello, Esteban Solari, Tareq Ibrahim, Stephan G. Nekolla,
Abstract Background The clinical indication to revascularization of coronary chronic total occlusions (CTO) is set on viability assessment through well-established imaging methods. Precise characterization of the myocardium allows a better interventional risk stratification before revascularization. Hybrid positron emission tomography/magnetic resonance (PET/MR) scanners allow the combination of image based biomarkers through simultaneous acquisition and may potentially improve the prediction of therapy ...
Tópico(s): Advanced MRI Techniques and Applications
2021 - Oxford University Press | European Heart Journal
Esteban Solari, S. Schahoff, Isabel Rauscher, Wolfgang Weber, Nassir Navab, M. Eiber, Stephan G. Nekolla,
Ziel/Aim Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) and magnetic resonance imaging (MRI) are the main imaging techniques for prostate cancer (PCa) diagnosis. Previously, we showed that radiomics have the potential to generate an image-based PCa staging by combining information from both PSMA PET and MRI radiomics to predict Gleason scores. In this work, we investigate the power of deep neural networks to predict the PI-RADS v2 score, an MRI-based diagnostic ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2022 - Schattauer Verlag | Nuklearmedizin - NuclearMedicine
Borjana Bogdanović, H. Porger, T. Hekimsoy, Sandra van Marwick, C. Meisinger, Esteban Solari, W. Weber, Stephan G. Nekolla,
Ziel/Aim Die kürzlich eingeführten sogenannten digitalen PET/CT Systeme bieten die Möglichkeit an, die Datenaufnahme- und Rekonstruktionsprotokolle anzupassen. Wir wollten das verbesserte Protokoll für F18-PSMA-Liganden mit ihren kleinen Läsionen und intensiver Tracer-Aufnahme identifizieren.
Tópico(s): Prostate Cancer Treatment and Research
2022 - Schattauer Verlag | Nuklearmedizin - NuclearMedicine
Esteban Solari, T. Hekimsoy, Sylvia Schachoff, Matthias Eiber, Nassir Navab, Wolfgang Weber, Stephan G. Nekolla,
Tópico(s): Cancer Genomics and Diagnostics
2024 - Elsevier BV | Physica Medica
Borjana Bogdanović, Esteban Solari, Alberto Villagrán Asiares, Sandra van Marwick, Sylvia Schachoff, Matthias Eiber, Wolfgang Weber, Stephan G. Nekolla,
In patients with increasing PSA and suspicion for prostate cancer, but previous negative biopsies, PET/MRI is used to test for tumours and target potential following biopsy. We aimed to determine different PSMA PET timing effects on signal kinetics and test its correlation with the patients' PSA and Gleason scores (GS).A total of 100 patients were examined for 900 s using PET/MRI approximately 1-2 h p.i. depending on the tracer used (68Ga-PSMA-11, 18F-PSMA-1007 or 18F-rhPSMA7). The scans were reconstructed ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2023 - Springer Nature | European Journal of Hybrid Imaging