Produção Nacional
Revisado por pares
... the University of São Paulo, Third Division (Professor Eurico da Silva Bastos), São Paulo, Brazil aHead of the group ...
Tópico(s): Anorectal Disease Treatments and Outcomes
1965 - Lippincott Williams & Wilkins | Diseases of the Colon & Rectum
Produção Nacional
Revisado por pares
Felipe José Figliolini, Daher E. Cutait, Mário Ramos de Oliveira, Eurico da Silva Bastos,
Conclusions Rectosigmoidal hemangioma is of extremely rare occurrence. The diagnosis is based on proctoscopic and radiologic examination. The cause is unknown and the prognosis is always serious because of the danger of uncontrollable hemorrhage that may occur at any moment. Treatment is surgical.
Tópico(s): Gastrointestinal disorders and treatments
1961 - Lippincott Williams & Wilkins | Diseases of the Colon & Rectum
María José Santos, Diana Carmona-Fernandes, Joana Caetano‐Lopes, Inês P. Perpétuo, Bruno Vidal, Susana Capela, José Canas da Silva, João Eurico Fonseca,
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2011 - Springer Science+Business Media | Rheumatology International
Joaquim Polido‐Pereira, Ana Maria Rodrigues, Helena Canhão, Fernando Saraiva, José António Pereira da Silva, João Eurico Fonseca,
Primary biliary cirrhosis (PBC) is an autoimmune disease in which intrahepatic bile ducts are targeted by an immune-mediated injury. This disease tends to progress to fibrosis and cirrhosis with hepatic failure. The authors report a case of a 50-year-old rheumatoid arthritis (RA) patient, with erosions and seropositive for rheumatoid factor and anti-citrullinated peptide antibodies, with 18 years disease duration refractory to prednisolone and several disease-modifying antirheumatic drugs, either ...
Tópico(s): Systemic Lupus Erythematosus Research
2011 - Springer Science+Business Media | Clinical Rheumatology
María José Santos, Diana Carmona-Fernandes, Susana Capela, José Canas da Silva, João Eurico Fonseca,
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2010 - Springer Science+Business Media | Clinical Rheumatology
Produção Nacional
Revisado por pares
Leda Solano de Freitas Souza, Eduardo Antônio Gonçalves Ramos, Fernándo Martins Carvalho, Virgínia Maria Castro Ribeiro Guedes, Lídia Silva Souza, Cristiane Rocha, Andréa Barreto Soares, Luciana de Freitas Velloso, Izolete Santos Macedo, Fernanda Edna Araújo Moura, Marilda Mendonça Siqueira, Silvana T. Fortes, Cibele Cruz de Jesus, Christiane M. G. Santiago, Ana Maria da Silva Carvalho, Eurico Arruda,
Abstract A cohort of children attending a day care center in Salvador (Bahia, Brazil) was studied prospectively to determine the incidence of viral respiratory infectious episodes and to identify the viruses associated with them. Two hundred seventy‐one nasopharyngeal samples were collected over a 1‐year period for examination, using indirect immunofluorescence with monoclonal antibodies against adenovirus, influenza A and B, parainfluenzae 1–3, and respiratory syncytial virus, and reverse transcriptase‐ ...
Tópico(s): Respiratory viral infections research
2003 - Wiley | Pediatric Pulmonology
Edgar Tavares-da-Silva, Eurico Pereira, Ana Salomé Pires, Rita Neves, Catarina Isabel Braz Guilherme, Inês A. Marques, Ana Margarida Abrantes, Ana Cristina Gonçalves, Francisco Caramelo, R. Silva-Teixeira, Fernando Mendes, Arnaldo Figueiredo, Maria Filomena Botelho,
Antitumor therapies based on Cold Atmospheric Plasma (CAP) are an emerging medical field. In this work, we evaluated CAP effects on bladder cancer. Two bladder cancer cell lines were used, HT-1376 (stage III) and TCCSUP (stage IV). Cell proliferation assays were performed evaluating metabolic activity (MTT assay) and protein content (SRB assay). Cell viability, cell cycle, and mitochondrial membrane potential (Δψm) were assessed using flow cytometry. Reactive oxygen and nitrogen species (RONS) and reduced ...
Tópico(s): Polyamine Metabolism and Applications
2021 - Multidisciplinary Digital Publishing Institute | Biology
Produção Nacional
Revisado por pares
Amauri Nélson Beutler, José Frederico Centurion, Maria Aparecida Pessôa da Cruz Centurion, Onã da Silva Freddi, Eurico Lucas de Sousa Neto, Cristian Luarte Leonel, Álvaro Pires da Silva,
Excessive traffic on the soil may affect soybean development. This research was carried out to evaluate soybean root development and grain yield under compacted soil, in an Oxisol. The following traffic treatments were used: T0 = no traffic; T1* = 1 passage of a 4 t tractor; and, T1, T2, T4 and T6, respectively for 1, 2, 4 and 6 passages of an 11 t tractor on the same location, each besides the other. After compaction, soybean [Glycine max cv. MG/BR 46 (Conquista)] was cultivated. The experiment was arranged ...
Tópico(s): Banana Cultivation and Research
2007 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
María José Santos, Diana Carmona-Fernandes, Helena Canhão, José Canas da Silva, João Eurico Fonseca, Víctor Gil,
Accelerated atherosclerosis represents a major problem in both systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) patients, and endothelial damage is a key feature of atherogenesis. We aimed to assess early endothelial changes in SLE and RA female patients (127 SLE and 107 RA) without previous CV events. Biomarkers of endothelial cell activation (intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), thrombomodulin (TM), and tissue factor (TF)) were measured ...
Tópico(s): Lipid metabolism and disorders
2012 - Public Library of Science | PLoS ONE
María José Santos, Luís Mendes Pedro, Helena Canhão, José Fernandes e Fernandes, José Canas da Silva, João Eurico Fonseca, Carlota Saldanha,
Rheological characteristics of blood are strongly linked to atherothrombosis in the general population, but its contribution to atherosclerosis in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) is currently unclear. This work examines the relationship between blood rheology, traditional cardiovascular (CV) risk factors, inflammation and subclinical atherosclerosis in SLE and RA.Whole blood viscosity (WBV), plasma viscosity (PV), erythrocyte deformability (ED), aggregation (EA) and erythrocyte ...
Tópico(s): Lipid metabolism and disorders
2011 - Elsevier BV | Atherosclerosis
Helena Canhão, Ana Maria Rodrigues, María José Santos, Diana Carmona-Fernandes, Bruno Filipe Bettencourt, Jing Cui, Fabiana Lucena Rocha, José António Pereira da Silva, Joaquim Polido‐Pereira, José Alberto Pereira Silva, José António Costa, Domingos Araújo, José António Pereira da Silva, Helena Santos, Cátia Duarte, Rafael Cáliz, Ileana Filipescu, Fernando Pimentel-Santos, Jaime Branco, Juan Sáinz, Robert M. Plenge, Daniel H. Solomon, Jácome Bruges‐Armas, José António Pereira da Silva, João Eurico Fonseca, Elizabeth W. Karlson,
Background . The aim of our work was to replicate, in a Southern European population, the association reported in Northern populations between PTPRC locus and response to anti-tumor necrosis factor (anti-TNF) treatment in rheumatoid arthritis (RA). We also looked at associations between five RA risk alleles and treatment response. Methods . We evaluated associations between anti-TNF treatment responses assessed by DAS28 change and by EULAR response at six months in 383 Portuguese patients. Univariate ...
Tópico(s): NF-κB Signaling Pathways
2015 - Hindawi Publishing Corporation | BioMed Research International
João Dias, Rita S. Rosa, Inês P. Perpétuo, Ana Maria Rodrigues, André Janeiro, Maria Manuela Costa, Luís Gaião, José António Pereira da Silva, João Eurico Fonseca, Gábriel Miltenberger-Miltényi,
Pachydermoperiostosis is a rare clinical entity characterized by skin thickening of the forehead, eyelids, and hands, digital clubbing, and periostosis. Two genes have been associated, HPGD and recently SLCO2A1. We present a detailed clinical and genetic description of an African pachydermoperiostosis patient with a SLCO2A1 mutation. Standard clinical and laboratory evaluation was carried out. Genetic screening was done with PCR followed by direct sequencing. We discuss the clinical features and ...
Tópico(s): Dupuytren's Contracture and Treatments
2013 - Elsevier BV | Seminars in Arthritis and Rheumatism
Márcio Navalho, Catarina Resende, Ana Maria Rodrigues, J. Alberto Pereira da Silva, João Eurico Fonseca, Jorge Campos, Helena Canhão,
Objective. To compare Doppler ultrasound (US) and 3.0-Tesla magnetic resonance imaging (3.0-T MRI) findings of synovial inflammation in the tendons and joints in an early polyarthritis cohort (patients who presented < 1 year after arthritis onset) using a bilateral hand and wrist evaluation. Also, to evaluate the diagnostic performance of US and MRI findings for rheumatoid arthritis (RA), their ability to predict RA as a diagnostic outcome, and their capacity to improve the accuracy of the 2010 American ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2013 - The Journal of Rheumatology Publishing Company Limited | The Journal of Rheumatology
Márcio Navalho, Catarina Resende, Ana Maria Rodrigues, Filipa Ramos, Augusto Gaspar, J. Alberto Pereira da Silva, João Eurico Fonseca, Jorge Campos, Helena Canhão,
To identify bilateral hand and wrist findings of synovial inflammation associated with progression to rheumatoid arthritis (RA) in very-early-RA cohort (VERA) (duration, <3 months) and early-RA cohort (ERA) (duration, 3 months), to test tenosynovitis as a magnetic resonance (MR) imaging additional parameter for improving diagnostic accuracy of the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) RA classification criteria, and to evaluate the symmetry of joint and tendon ...
Tópico(s): Viral Infections and Immunology Research
2012 - Radiological Society of North America | Radiology
Vasco C. Romão, María José Santos, Joaquim Polido‐Pereira, Cátia Duarte, Patrícia Nero, Cláudia Miguel, José António Costa, Miguel Bernardes, Fernando Pimentel-Santos, Filipe Barcelos, Lúcia Costa, José António Melo Gomes, José António Pereira da Silva, Jaime Branco, José Canas da Silva, José António Pereira da Silva, João Eurico Fonseca, Helena Canhão,
To compare the effectiveness of TNF inhibitors (TNFi) and tocilizumab in rheumatoid arthritis (RA) treatment, according to different response criteria.We included RA patients registered in the Rheumatic Diseases Portuguese Register treated with TNFi or tocilizumab for at least 6 months, between January 2008 and July 2013. We assessed remission/low disease activity (LDA) at 6 months according to DAS28, CDAI, and SDAI, as well as Boolean ACR/EULAR remission and EULAR response rate, adjusting for measured ...
Tópico(s): Systemic Lupus Erythematosus Research
2015 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
Carminda Maria Goersch Fontenele Lamboglia, Vanina Tereza Barbosa Lopes da Silva, José Eurico de Vasconcelos Filho, Mônica Helena Neves Pereira Pinheiro, Marilene Calderaro Munguba, Francisco Valmar Isaias Silva Júnior, Fernando Alberto Ramirez de Paula, Carlos Antônio Bruno da Silva,
Improper use of electronic media is considered a major contributing factor to childhood obesity. However, exergames, a new generation of active games, have made it possible to combine electronic entertainment with physical exercise. The purpose of this systematic review was to analyze the use of exergaming as a strategic tool in the fight against childhood obesity. Information was retrieved from the databases SciELO, LILACS, Pubmed, Ebsco, and Science Direct, using the search words “egames,” “exergames,” “ ...
Tópico(s): Children's Physical and Motor Development
2013 - Hindawi Publishing Corporation | Journal of Obesity
Produção Nacional
Revisado por pares
Maximiliano Isoppo Schaun, Thiago Dipp, Juliane da Silva Rossato, Eurico Nestor Wilhelm, Ronei Silveira Pinto, Anderson Rech, Rodrigo Della Méa Plentz, Paulo Ivo Homem de Bittencourt, Álvaro Reischak-Oliveira,
The vascular endothelium plays a key role in arterial wall homeostasis by preventing atherosclerotic plaque formation. A primary causal factor of endothelial dysfunction is the reactive oxygen species. Aerobic exercise is ascribed as an important adjuvant therapy in endothelium‐dependent cardiovascular disease. However, little is known about the effects of concurrent (aerobic + strength) training on that. For a comparison of the effects of aerobic and concurrent physical training on endothelial function, ...
Tópico(s): Thermoregulation and physiological responses
2011 - Wiley | Cell Biochemistry and Function
Produção Nacional
Luiz Juliano Valério Geron, Sílvia Cristina de Aguiar, Joilma Toniolo Honório de Carvalho, Gregory Duarte Juffo, Ana Paula da Silva, Eurico Lucas de Sousa Neto, Kallynka Samara Martins Coelho, Jocilaine Garcia, Leomar Custódio Diniz, Edson Júnior Heitor de Paula,
This study aimed to evaluate the inclusion of 0.0%, 0.4%, 0.8%, and 1.2% slow release urea (SRU) in sheep feed on the intake and total digestibility coefficient (DC) of nutrients and ruminal parameters of sheep living in tropical regions. Four sheep with a body weight (BW) average of 30.8 ± 1.7 kg were assigned to a Latin square design. The animals were placed in metabolic cages and received two meals a day. Intake data and DC of nutrients of the sheep were subjected to analysis of variance and differences ...
Tópico(s): Animal Nutrition and Physiology
2016 - UNIVERSIDADE ESTADUAL DE LONDRINA | Semina Ciências Agrárias
Produção Nacional
Revisado por pares
Julianne V. de Carvalho, Rodrigo O. de Castro, Elaine Zayas Marcelino da Silva, Paola Paz Silveira, Mara E. da Silva-Januário, Eurico Arruda, Maria Célia Jamur, Constance Oliver, Renato Santana Aguiar, Luis L. P. daSilva,
Nef is an HIV-1 accessory protein that promotes viral replication and pathogenesis. A key function of Nef is to ensure sustained depletion of CD4 and MHC-I molecules in infected cells by inducing targeting of these proteins to multivesicular bodies (MVBs), and ultimately to lysosomes for degradation. Nef also affects cellular secretory routes promoting its own secretion via exosomes. To better understand the effects of Nef on the exocytic pathway, we investigated whether this viral factor modifies ...
Tópico(s): Reproductive System and Pregnancy
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Tirzhá Lins Porto Dantas, F. Murilo T. Luna, Ivanildo José da Silva, A. Eurico B. Torres, Diana C. S. Azevedo, Alı́rio E. Rodrigues, Regina de Fátima Peralta Muniz Moreira,
In this study, the fixed - bed adsorption of carbon dioxide and a carbon dioxide - nitrogen mixture on zeolite 13X was investigated. The adsorption equilibrium and breakthrough curves were determined at different temperatures - 301 - 306 K, 323 K, 373 K and 423 K. A model based on the LDF approximation for the mass transfer, considering the energy and momentum balances, was used to describe the adsorption kinetics of carbon dioxide and a carbon dioxide - nitrogen mixture. The model acceptably reproduced all ...
Tópico(s): Membrane Separation and Gas Transport
2011 - Springer Science+Business Media | Brazilian Journal of Chemical Engineering
Produção Nacional
Edna Peixoto da Rocha Amorim, Flávia Waneska Rodrigues de Andrade, Edlene Maria da Silva Moraes, Júlio César da Silva, Rosangela da Silva Lima, Eurico Eduardo Pinto de Lemos,
O presente trabalho teve como objetivo determinar a atividade de diferentes concentrações de óleos essenciais e extratos vegetais sobre o crescimento de Ralstonia solanacearum e a incidência do moko em mudas de bananeira. Foram avaliadas diferentes concentrações de óleos essenciais de citronela, eucalipto citriodora, cravo-da-índia e gengibre: 1,25%; 3,5%; 3,75% e 5% e de extratos de cravo-da-índia, gengibre, canela e melão-de-são-caetano: 5%, 10%, 15% e 20%, medindo-se o halo de inibição da bactéria, ...
Tópico(s): Plant-Microbe Interactions and Immunity
2011 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Produção Nacional
Revisado por pares
Tirzhá Lins Porto Dantas, F. Murilo T. Luna, Ivanildo José da Silva, A. Eurico B. Torres, Diana C. S. Azevedo, Alı́rio E. Rodrigues, Regina de Fátima Peralta Muniz Moreira,
The reduction of carbon dioxide emissions from flue gases can be achieved using post-combustion capture technologies such as adsorption. In this paper, we report the continuous separation of a 15% mol/mol carbon dioxide–nitrogen mixture through the pressure swing adsorption (PSA) process. To this aim, zeolite 13X was used as the adsorbent in a fixed-bed column at different temperatures. The adsorption equilibrium of CO2 was described according to the Toth isotherm, while the N2 adsorption did not ...
Tópico(s): Membrane Separation and Gas Transport
2011 - Elsevier BV | Chemical Engineering Journal
Produção Nacional
Revisado por pares
Rafael B. Rios, Francisco Wilton Miranda Da Silva, A. Eurico B. Torres, Diana C. S. Azevedo, Célio L. Cavalcante,
Tópico(s): Hydrocarbon exploration and reservoir analysis
2009 - Springer Science+Business Media | Adsorption
Manuel Fernandes Marques, Luís Henrique Barros, Bruno Lopes Correia, Eurico Lopes da Silva, Ricardo Rodrigues‐Pinto,
Case: We report a case of postoperative left-sided Horner syndrome (blepharoptosis, miosis, and anhidrosis) after revision surgery for cervical spondylotic myelopathy. A C4 corpectomy and an anterior cervical fusion from C3 to C5 were performed through a left longitudinal approach in a patient with a surgical history of an anterior discectomy and a fusion from C5 to C6. One year after the revision surgery, the patient had recovered from the anhidrosis and the miosis, but the blepharoptosis was not ...
Tópico(s): Spine and Intervertebral Disc Pathology
2018 - Lippincott Williams & Wilkins | JBJS Case Connector
Elsa Vieira‐Sousa, João Cavaleiro, Ana Filipa Mourão, Ana Maria Rodrigues, António Albino‐Teixeira, Fernando Pimentel-Santos, Filipa Oliveira‐Ramos, Helena Canhão, Joaquim Polido‐Pereira, João Eurico Fonseca, José António Pereira da Silva, José Carlos Romeu, José Melo Gomes, Lúcia Helena Rodrigues Costa, Luís Felipe G. da Graça, Maria Leandro, María José Santos, Pedro Machado, Sofía Ramiro,
Tópico(s): Medical and Biological Sciences
2018 - Sociedade Portuguesa de Reumatologia | Acta reumatológica portuguesa
Mónica Bogas, Pedro Machado, Ana Filipa Mourão, Lúcia Costa, María José Santos, João Eurico Fonseca, José António Pereira da Silva, Helena Canhão,
Tópico(s): Autoimmune and Inflammatory Disorders Research
2010 - Springer Science+Business Media | Clinical Rheumatology
Produção Nacional
Revisado por pares
Alyne de Melo Fonseca, Cristina da Costa Bernardes Araújo, Julianna Henriques da Silva, Thiago da Silva Honório, Luiz Eurico Nasciutti, Lúcio Mendes Cabral, Flávia Almada do Carmo, Valéria Pereira de Sousa,
The primary course of melanoma treatment involves surgery in association with chemotherapy. One potential agent is vinorelbine (VNR). While it displays anti-proliferative activity against melanoma cell lines, it presents a low oral bioavailability and intravenous administration often causes irritation, phlebitis and pain at the injection site. The aim of this study was to develop Pluronic® F-127 (PF-127) hydrogels containing VNR for the transdermal route of administration. Hydrogels composed of either ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2021 - Elsevier BV | Journal of Drug Delivery Science and Technology
Produção Nacional
Revisado por pares
Edna Lúcia Souza, João Gabriel Rosa Ramos, José Luiz Proença‐Módena, Andréa Diniz, Gisele Pereira de Carvalho, Isolina Allen Ciuffo, César A. Araújo‐Neto, Sandra C. Andrade, Luciana Sandra Bastos de Souza, Eurico Arruda, L. Silva,
A cross-sectional study was carried out over a period of 12 months to investigate the occurrence of human bocavirus (HBoV) infection in infants hospitalized for respiratory infections in a teaching hospital in Salvador, Brazil, and to describe the clinical manifestations of this infection. Nasopharyngeal aspirates were collected from the children and immunofluorescence and polymerase chain reaction were performed to investigate the presence of respiratory viruses. HBoV was detected in 4 out of 66 ...
Tópico(s): Pneumonia and Respiratory Infections
2009 - Oxford University Press | Journal of Tropical Pediatrics
Tiago Santos, Roberto Estêvão, Luís Antunes, Victor Certal, Joaquim Castro Silva, Eurico Monteiro,
To evaluate the clinical and histopathological factors affecting the prognosis of patients with squamous cell locoregional advanced laryngeal cancer.A retrospective chart review was conducted of 121 patients with locoregional advanced laryngeal cancer, primarily treated with surgery from 2007 to 2011. Disease-free survival and overall survival rates were analysed as oncological outcomes. Prognostic variables, namely gender, pharyngeal invasion, pathological assessment of tumour and nodal stage, ...
Tópico(s): Cancer Diagnosis and Treatment
2016 - Cambridge University Press | The Journal of Laryngology & Otology
Jorge Oliveira, Cristina Dias, E. Redeker, Eurico Leandro Bandeirinha Pinto da Costa, João Silva, Margarida Reis Lima, Johan T. den Dunnen, Rosário Santos,
The establishment of Locus Specific Databases (LSDB) is a crucial aspect for the Human Genetics field and one of the aims of the Human Variation Project. We report the development of a publicly accessible LSDB for the NIPBL gene (http://www.lovd.nl/NIPBL) implicated in Cornelia de Lange Syndrome (CdLS). This rare disorder is characterized by developmental and growth retardation, typical facial features, limb anomalies, and multiple organ involvement. Mutations in the NIPBL gene, the product of which ...
Tópico(s): Genomic variations and chromosomal abnormalities
2010 - Wiley | Human Mutation