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Artigo Acesso aberto Brasil Produção Nacional

Evandro Brandão Secco, Edmur Antônio Stoppa,

O presente artigo é resultado de uma investigação sobre o PELC, Programa Esporte e Lazer da Cidade, uma política pública de iniciativa do Governo Federal e executada pelo Município de São Bernardo do Campo, região metropolitana de São Paulo. Seu objetivo é apresentar as particularidades do desenvolvimento dessa política a partir de um diálogo com os princípios gerais das diretrizes da política nacional de promoção da saúde. Trata-se de um estudo de caso, composto por uma pesquisa de campo, com análise ...

Tópico(s): Business and Management Studies

2023 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Licere

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Taylor Reis, Carlos Otávio Brandão, Evandro Silva Freire Coutinho, Eliasz Engelhardt, Jerson Laks,

SUMMARY Aims Depression is a highly prevalent disorder in the elderly and one of the risk factors for developing dementia. The present study involves patients with Alzheimer's disease (AD), geriatric major depressive disorder (MDD) and cognitively healthy controls aiming to compare baseline cerebrospinal fluid (CSF) biomarkers. Methods The study included 52 patients with more than 60 years of age with a diagnosis of MDD, AD, and healthy controls. All individuals underwent a medical history, physical, ...

Tópico(s): Functional Brain Connectivity Studies

2012 - Wiley | CNS Neuroscience & Therapeutics

Artigo Acesso aberto Revisado por pares

Evandro de Azambuja, Mariana Brandão, Hans Wildiers, Annouschka Laenen, Sandrine Aspeslagh, Christel Fontaine, Joëlle Collignon, Willem Lybaert, Jolanda Verheezen, Annemie Rutten, Peter Vuylsteke, Jean‐Charles Goeminne, Wim Demey, Dominique Van Beckhoven, Jessika Deblonde, Sylvie Rottey, Tatjana Geukens, Kevin Punie, Kristof Bafort, Leïla Belkhir, Nathalie Bossuyt, Vincent Colombié, Christine Daubresse, Nicolás Dauby, Paul De Munter, Didier Delmarcelle, Mélanie Delvallee, Rémy Demeester, Quentin Delefortrie, Thierry Dugernier, Xavier Holemans, I Louviaux, PierreYves Machurot, Philippe Minette, Saphia Mokrane, Catherine Nachtergal, Séverine Noirhomme, Denis Piérard, Camélia Rossi, Carole Schirvel, Erica Sermijn, Frank Staelens, Filip Triest, Dominique Van Beckhoven, Nina Van Goethem, Jens Van Praet, Anke Vanhoenacker, R. Verstraete, Elise Willems, Chloé Wyndham-Thomas,

Cancer seems to have an independent adverse prognostic effect on COVID-19-related mortality, but uncertainty exists regarding its effect across different patient subgroups. We report a population-based analysis of patients hospitalised with COVID-19 with prior or current solid cancer versus those without cancer.We analysed data of adult patients registered until 24 May 2020 in the Belgian nationwide database of Sciensano. The primary objective was in-hospital mortality within 30 days of COVID-19 ...

Tópico(s): COVID-19 Clinical Research Studies

2020 - Elsevier BV | ESMO Open

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Carolina Moretto Carnielli, Thayná Melo de Lima Morais, Fábio Malta de Sá Patroni, Ana Carolina Prado Ribeiro, Thaís Bianca Brandão, Evandro Sobroza, Leandro Luongo de Matos, Luiz Paulo Kowalski, Adriana Franco Paes Leme, Rebeca Kawahara, Morten Thaysen‐Andersen,

While altered protein glycosylation is regarded a trait of oral squamous cell carcinoma (OSCC), the heterogeneous and dynamic glycoproteome of tumor tissues from OSCC patients remain unmapped. To this end, we here employ an integrated multi-omics approach comprising unbiased and quantitative glycomics and glycoproteomics applied to a cohort of resected primary tumor tissues from OSCC patients with (n = 19) and without (n = 12) lymph node metastasis. While all tumor tissues displayed relatively uniform ...

Tópico(s): Peptidase Inhibition and Analysis

2023 - Elsevier BV | Molecular & Cellular Proteomics

Carta Brasil Produção Nacional Revisado por pares

Renato D. Lópes, Weimar Kunz Sebba Barroso, Andréa Araújo Brandão, Eduardo Costa Duarte Barbosa, Marcus Vinícius Bolívar Malachias, Marco Mota Gomes, Celso Amodeo, Rui Póvoa, Margaret Assad Cavalcante, Dalton Bertolim Précoma, Antônio Carlos Sobral Sousa, João Miguel Malta Dantas, Evandro José Cesarino, Paulo César Brandão Veiga Jardim,

A systematic, nationwide assessment of care of patients with hypertension in Brazil is needed. The objective of the First National Registry of Patients with Hypertension in Brazil is to evaluate the clinical profile, treatment patterns, and outcomes of diagnosed hypertensive patients in the country.

Tópico(s): Global Public Health Policies and Epidemiology

2018 - Elsevier BV | American Heart Journal

Artigo Brasil Produção Nacional Revisado por pares

Evandro Sapelli, Tiago A. S. Brandão, Haidi D. Fiedler, Faruk Nome,

Mixtures of Zn(II) and 8-hydroxyquinoline (8QOH) in a 1:2 proportion, in aqueous solutions, result in fast complexation, followed by precipitation. Addition of 0.05 M sodium dodecyl sulfate (SDS), N-dodecyl-N,N-dimethylammonio-1-propanesulfonate (SB3-12), N-hexadecyl-N,N-dimethylammonio-1-propanesulfonate (SB3-16) or Triton X-100 results in considerable retardation of precipitation. In the presence of SDS, SB3-12, SB3-16 and Triton X-100 the 8QOH chelates are only kinetically stable in solution and ...

Tópico(s): Surfactants and Colloidal Systems

2007 - Elsevier BV | Journal of Colloid and Interface Science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Sandra Cristina Pereira Costa Fuchs, Carlos Eduardo Poli‐de‐Figueiredo, José Albuquerque de Figueiredo Neto, Luiz César Nazário Scala, Paul K. Whelton, Francisca Mosele, Renato Gorga Bandeira de Mello, José Fernando Vilela-Martin, Leila Beltrami Moreira, Hilton Chaves, Marco Mota Gomes, Marcos Roberto de Sousa, Ricardo Pereira e Silva, Iran Castro, Evandro José Cesarino, Paulo César Brandão Veiga Jardim, João Guilherme Bezerra Alves, André Avelino Steffens, Andréa Araújo Brandão, Fernanda Marciano Consolim‐Colombo, Paulo Ricardo de Alencastro, Abrahão Afiune Neto, Antônio Cláudio Lucas da Nóbrega, Roberto Silva Franco, Dário Celestino Sobral Filho, Alexandro Bordignon, Fernando Nobre, Rosane Paixão Schlatter, Miguel Gus, Felipe Costa Fuchs, Otávio Berwanger, Flávio Danni Fuchs,

Prehypertension is associated with higher cardiovascular risk, target organ damage, and incidence of hypertension. The Prevention of Hypertension in Patients with PreHypertension (PREVER-Prevention) trial aimed to evaluate the efficacy and safety of a low-dose diuretic for the prevention of hypertension and end-organ damage.This randomized, parallel, double-blind, placebo-controlled trial was conducted in 21 Brazilian academic medical centers. Participants with prehypertension who were aged 30 to ...

Tópico(s): Cardiovascular Health and Disease Prevention

2016 - Wiley | Journal of the American Heart Association

Carta Brasil Produção Nacional Revisado por pares

Dayvison Francis Saraiva Freitas, Antônio Carlos Francesconi do Valle, Tullia Cuzzi, Luciana Gomes Pedro Brandão, Rosely Maria Zancopé‐Oliveira, Maria Clara Gutierrez Galhardo,

... this authorL.G.P. Brandão, L.G.P. Brandão Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil 4365, Manguinhos, ... this authorL.G.P. Brandão, L.G.P. Brandão Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil 4365, Manguinhos, ...

Tópico(s): Cutaneous lymphoproliferative disorders research

2011 - Oxford University Press | British Journal of Dermatology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marcelo Libório Schwarzbold, Alexandre Paim Díaz, Evandro Tostes Martins, Armanda Carla Teixeira Brandão Fragata Rufino, Lúcia Nazareth Amante, Maria Emília Rodrigues de Oliveira Thais, João Quevedo, Alexandre Hohl, Marcelo Neves Linhares, Roger Walz,

Abstract: Psychiatric disorders after traumatic brain injury (TBI) are frequent. Researches in this area are important for the patients' care and they may provide hints for the comprehension of primary psychiatric disorders. Here we approach epidemiology, diagnosis, associated factors and treatment of the main psychiatric disorders after TBI. Finally, the present situation of the knowledge in this field is discussed. Keywords: psychiatric disorders, traumatic brain injury, neuropsychiatry, diagnostic, ...

Tópico(s): Psychosomatic Disorders and Their Treatments

2008 - Dove Medical Press | Neuropsychiatric Disease and Treatment

Artigo Brasil Produção Nacional Revisado por pares

Elizete Pereira, Rafael L. Gomes, Natália Freire, Evandro Guimarães de Aguiar, Maria G.L. Brandão, Vagner Rodrigues Santos,

This study evaluated the susceptibility of oral pathogenic microorganisms Candida albicans, Streptococcus mutans, Staphylococcus aureus, and Aggregatibacter actinomycetemcomitans to Brazilian medicinal plant extracts of Schinus terebinthifolius (aroeira), Croton campestris (velame), Lafoensia pacari (pacari), Centaurium erythraea (centáurea), Stryphnodendron adstringens (barbatimão), and Anacardium humile (cajuzinho-do-cerrado), as compared to standardized antimicrobial agents (nystatin, chloramphenicol ...

Tópico(s): Ethnobotanical and Medicinal Plants Studies

2010 - Thieme Medical Publishers (Germany) | Planta Medica

Artigo Acesso aberto

Kirlene Salgado Fernandes, Evandro de Azevedo Alvarenga, Paulo Roberto Gomes Brandão, Vanessa de Freitas Cunha Lins,

Hopeite-type phosphate coatings in which zinc is partially replaced by other metals like manganese and nickel are of great interest for the automotive and home appliance industries. Such industries use phosphate conversion coatings on galvanized steels in association with cataphoretic electropainting. Zinc phosphates modified with manganese and nickel are isomorphic with the hopeite, and the phase identification using X-ray diffraction is difficult. In this paper, the phosphate coatings are identified ...

Tópico(s): X-ray Diffraction in Crystallography

2011 - SciELO | Rem Revista Escola de Minas

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Márcio Sommer Bittencourt, Giuliano Generoso, Pedro Melo, Driele Peixoto, Érique José Farias Peixoto de Miranda, Evandro Tinoco Mesquita, Andréa Araújo Brandão, José Francisco Kerr Saraiva, Sílvio Henrique Barberato, Fernando Bacal, Marcelo Antônio Cartaxo Queiroga Lopes,

1. Introduction and General Concepts The pandemic resulting from the novel coronavirus (SARS-CoV-2) infection, named COVID-19, emerged in Wuhan, China, in December 2019., Since then, millions of people around the world have been affected and hundreds of thousands have died. The virus spreads mainly from person to person,, directly via the airways or indirectly through contact with contaminated surfaces and objects. Respiratory infections occur through the transmission of virus-filled droplets (> 5 μm, ...

Tópico(s): Infection Control and Ventilation

2020 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Artigo Brasil Produção Nacional Revisado por pares

Evandro José Lima Rego, A. C. Bento, Rodrigo Álvaro Brandão Lopes-Martins, Edson Antunes, J. C. Novello, Sérgio Marangoni, José R. Giglio, Bárbara Oliveira, Gilberto De Nucci,

The venom of the Brazilian spider Phoneutria nigriventer was fractionated using a C18 μBondapack reverse-phase high-performance liquid chromatography column. The resulting fractions were assayed in the rabbit perfused corpus cavernosum tissue to identify those fractions responsible for the corpus cavernosum relaxation. Two fractions (A and B) with retention times of 18.1 and 36.7 min, respectively, induced relaxation of corpus cavernosum strips. Fraction A was selected for further biochemical characterization. ...

Tópico(s): Healthcare and Venom Research

1996 - Elsevier BV | Toxicon

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Julio Cesar Betiol, Laura Sichero, Henrique Olival Costa, Leandro Luongo de Matos, Maria Antonieta Andreoli, Silvaneide Ferreira, Sheila F. Faraj, Evandro Sobroza de Mello, João Simão Sobrinho, Lenine Garcia Brandão, Cláudio Roberto Cernea, Marco Aurélio Vamondes Kulcsar, Fábio Roberto Pinto, Antônio José Gonçalves, Marcelo Benedito Menezes, Leonardo Silva, Lia Mara Rossi, Rafaella Almeida Lima Nunes, Lara Termini, Luisa L. Villa,

Human papillomavirus (HPV) prevalence in head and neck squamous cell carcinomas (HNSCC) diverges geographically. The reliability of using p16(INK4a) expression as a marker of viral infection is controversial in HNSCC. We evaluated HPV types and HPV-16 variants prevalence, and p16(INK4a) expression in HNSCC specimens provided by two different Institutions in São Paulo.HPV DNA from formalin-fixed specimens was accessed by Inno-LiPA, HPV-16 variants by PCR-sequencing, and p16(INK4a) protein levels by ...

Tópico(s): Cancer-related Molecular Pathways

2016 - BioMed Central | Infectious Agents and Cancer

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Pedro Henrique Scheidt Figueiredo, Márcia Maria Oliveira Lima, Henrique Silveira Costa, Rosalina Tossige Gomes, Camila Danielle Cunha Neves, Evandro Silveira de Oliveira, Frederico Lopes Alves, Vanessa Gomes Brandão Rodrigues, Emílio Henrique Barroso Maciel, Cláudio H. Balthazar,

Inspiratory muscle function may be affected in patients with End-Stage Renal Disease (ESRD), further worsening the functional loss in these individuals. However, the impact of inspiratory muscle weakness (IMW) on the functional capacity (FC) of hemodialysis patients remains unknown. Thus, the present study aimed to evaluate the impact of IMW on FC in ESRD patients undergoing hemodialysis.ESRD patients on hemodialysis treatment for more than six months were evaluated for inspiratory muscle strength ...

Tópico(s): Nutrition and Health in Aging

2017 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renato Vasconcelos Alves, Fabiano H. Brandão, José Evandro Prudente de Aquino, Maria R. M. S. Carvalho, Suzana Maria Giancoli, Eduado A. P. Younes,

Intradermal nevi are common benign pigmented skin tumors. Their occurrence within the external auditory canal is uncommon. The clinical and pathologic features of an intradermal nevus arising within the external auditory canal are presented, and the literature reviewed.

Tópico(s): Reconstructive Facial Surgery Techniques

2005 - Elsevier BV | Brazilian Journal of Otorhinolaryngology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Flávio Danni Fuchs, Sandra Cristina Pereira Costa Fuchs, Leila Beltrami Moreira, Miguel Gus, Antônio Cláudio Lucas da Nóbrega, Carlos Eduardo Poli‐de‐Figueiredo, Décio Mion, Luiz A. Bortoloto, Fernanda Marciano Consolim‐Colombo, Fernando Nobre, Eduardo Barbosa Coelho, José Fernando Vilela-Martin, Heitor Moreno, Evandro José Cesarino, Roberto Jorge da Silva Franco, Andréa Araújo Brandão, Marcos Roberto de Sousa, Antônio Luiz Pinho Ribeiro, Paulo César Brandão Veiga Jardim, Abrahão Afiune Neto, Luiz César Nazário Scala, Marco Mota, Hilton Chaves, João Guilherme Bezerra Alves, Dário Celestino Sobral Filho, Ricardo Pereira e Silva, José Albuquerque de Figueiredo Neto, Maria Cláudia Irigoyen, Iran Castro, André Avelino Steffens, Rosane Paixão Schlatter, Renato Gorga Bandeira de Mello, Francisca Mosele, Flávia Ghizzoni, Otávio Berwanger,

Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to 50 years of age. Non-drug interventions to prevent hypertension have had low effectiveness. In individuals with previous cardiovascular disease or diabetes, the use of BP-lowering agents reduces the incidence of major cardiovascular events. In the absence of higher baseline risk, the use of ...

Tópico(s): Sodium Intake and Health

2011 - Springer Science+Business Media | Trials

Editorial Acesso aberto Revisado por pares

Wolney de Andrade Martins, Gláucia Maria Moraes de Oliveira, Andréa Araújo Brandão, Ricardo Mourilhe‐Rocha, Evandro Tinoco Mesquita, José Francisco Kerr Saraiva, Fernando Bacal, Marcelo Antônio Cartaxo Queiroga Lopes,

A pandemia da COVID-19 A Organização Mundial da Saúde reconheceu a COVID-19 como pandemia em 11 de março de 2020 e, desde então, essa emergência de saúde pública converteu-se na principal causa de óbitos no mundo, o que tornou seu enfrentamento uma prioridade inquestionável. Ao escrevermos este editorial contabilizávamos 86.969.386 casos confirmados e 1.915.657 mortes por COVID-19 no mundo, dos quais 8.013.708 casos ocorreram no Brasil e resultaram em 201.460 mortes. Segundo as projeções do Institute ...

Tópico(s): COVID-19 Clinical Research Studies

2021 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Artigo Brasil Produção Nacional Revisado por pares

Luiz Gonzaga Vaz Coelho, Magna Cottini Fonseca Passos, Y. Chausson, Evandro Luis de Oliveira Costa, Annubia Freitas Maia, M. J. C. C. Brandao, D. C. Rodrigues, Lúcia Porto Fonseca de Castro,

AbstractForty-eight patients with endoscopically proven duodenal ulcer (DU) and Helicobacter pylori infection detected by 14C-urea breath test (BT) were assigned to 5 days of treatment with furazolidone, metronidazole, and amoxicillin in addition to eventual classical anti-ulcer agents if necessary. Clinical evaluation and BT were repeated at 2, 6, and 18 months after therapy to determine H. pylori eradication or reinfection. Endoscopy was also repeated at 6 and 18 months after treatment to detect ...

Tópico(s): Veterinary medicine and infectious diseases

1992 - Taylor & Francis | Scandinavian Journal of Gastroenterology

Artigo Brasil Produção Nacional Revisado por pares

Lázaro Pinto Medeiros Neto, Luis Felipe das Chagas e Silva de Carvalho, Laurita dos Santos, Claudio A. Téllez Soto, Renata de Azevedo Canevari, André Bandiera de Oliveira Santos, Evandro Sobroza de Mello, Marina Aparecida Pereira, Cláudio Roberto Cernea, Lenine Garcia Brandão, Aírton Abrahão Martin,

Thyroid carcinomas are the most common endocrine malignancy. Inconclusive results for the analysis of malignancies are an issue in the diagnosis of thyroid carcinomas; 20% of thyroid cancer diagnoses are indeterminate or suspicious, resulting in a surgical procedure without immediate need. The use of Raman spectroscopy may help improve the diagnosis of thyroid carcinoma. In this study, 30 thyroid samples, including normal thyroid, goiter and thyroid cancer, were analyzed by confocal Raman spectroscopy. ...

Tópico(s): Bacillus and Francisella bacterial research

2016 - Elsevier BV | Photodiagnosis and Photodynamic Therapy

Artigo Brasil Produção Nacional Revisado por pares

Levy Carvalho Gomes, Richard Philip Brinn, Jaydione Luíz Marcon, Lucelle Araújo Dantas, Franmir Rodrigues Brandão, Janessa Sampaio de Abreu, Paulo Evandro Mendes Lemos, D. Michelle McComb, Bernardo Baldisserotto,

The objective of this experiment was to test the probiotic Efinol®L during transportation of cardinal tetra, Paracheirodon axelrodi (Schultz). For the transportation, fish were distributed in 18 plastic tanks, of which nine contained the Efinol®L (10 mg L−1; probiotic treatment) and the remaining had no probiotic (control treatment). Transport lasted 24 h and three different boxes of each treatment were sampled at 3, 12 and 24 h. Up to the 12-h sampling period, no significant difference in the survival ...

Tópico(s): Fish biology, ecology, and behavior

2008 - Wiley | Aquaculture Research

Revisão Acesso aberto Revisado por pares

Mariana Brandão, Rafael Caparica, Daniel Eiger, Evandro de Azambuja,

Abstract In this review, we discuss biomarkers of response and resistance to PI3K inhibitors (PI3Ki) in estrogen receptor-positive breast cancer, both in the early and advanced settings. We analyse data regarding PIK3CA mutations, PI3K pathway activation, PTEN expression loss, Akt signalling, insulin levels, 18F FDG-PET/CT imaging, FGFR1/2 amplification, KRAS and TP53 mutations. Most of the discussed data comprise retrospective and exploratory studies, hence many results are not conclusive. Therefore, among ...

Tópico(s): HER2/EGFR in Cancer Research

2019 - Elsevier BV | Annals of Oncology

Artigo Acesso aberto Revisado por pares

Rafael Caparica, François Richard, Mariana Brandão, Ahmad Awada, Christos Sotiriou, Evandro de Azambuja,

Beta-2 adrenergic receptor (ADRB2) mediates proliferation and treatment resistance in preclinical models of human epidermal growth factor receptor 2 positive (HER2+) breast cancer. We evaluated ADRB2 gene expression as a prognostic and predictive biomarker in patients with HER2+ early breast cancer.ADRB2 expression was retrieved from HER2+ patients enrolled in the FinHer study (N = 202), and 2 public datasets containing data from patients with HER2+ early breast cancer: one including patients who did ...

Tópico(s): Cancer Cells and Metastasis

2020 - Elsevier BV | Clinical Breast Cancer

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Beatriz Alves Guerra, Bruna B. Brandão, Silas Pinto, Willian Goulart Salgueiro, Evandro A. De‐Souza, Felipe C.G. Reis, Thiago M. Batista, Vanessa Cavalcante‐Silva, Vânia D’Almeida, Beatriz A. Castilho, Everardo M. Carneiro, Adam Antebi, William T. Festuccia, Marcelo A. Mori,

Dietary restriction (DR) improves health and prolongs lifespan in part by upregulating type III endoribonuclease DICER in adipose tissue. In this study, we aimed to specifically test which missing dietary component was responsible for DICER upregulation.We performed a nutrient screen in mouse preadipocytes and validated the results in vivo using different kinds of dietary interventions in wild type or genetically modified mice and worms, also testing the requirement of DICER on the effects of the ...

Tópico(s): Birth, Development, and Health

2019 - Elsevier BV | Molecular Metabolism

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Flávio Danni Fuchs, Sandra Cristina Pereira Costa Fuchs, Leila Beltrami Moreira, Miguel Gus, Antônio Cláudio Lucas da Nóbrega, Carlos Eduardo Poli‐de‐Figueiredo, Décio Mion, Luiz Aparecido Bortolotto, Fernanda Marciano Consolim‐Colombo, Fernando Nobre, Eduardo Barbosa Coelho, José Fernando Vilela-Martin, Heitor Moreno, Evandro José Cesarino, Roberto Jorge da Silva Franco, Andréa Araújo Brandão, Marcos Roberto de Sousa, Antônio Luiz Pinho Ribeiro, Paulo César Brandão Veiga Jardim, Abrahão Afiune Neto, Luiz César Nazário Scala, Marco Mota, Hilton Chaves, João Guilherme Bezerra Alves, Dário Celestino Sobral Filho, Ricardo Pereira e Silva, José Albuquerque de Figueiredo Neto, Maria Cláudia Irigoyen, Iran Castro, André Avelino Steffens, Rosane Paixão Schlatter, Renato Gorga Bandeira de Mello, Francisca Mosele, Flávia Ghizzoni, Otávio Berwanger,

Cardiovascular disease is the leading cause of death in Brazil, and hypertension is its major risk factor. The benefit of its drug treatment to prevent major cardiovascular events was consistently demonstrated. Angiotensin-receptor blockers (ARB) have been the preferential drugs in the management of hypertension worldwide, despite the absence of any consistent evidence of advantage over older agents, and the concern that they may be associated with lower renal protection and risk for cancer. Diuretics ...

Tópico(s): Renin-Angiotensin System Studies

2011 - Springer Science+Business Media | Trials

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Mônica Quintão, Sérgio Chermont, Luana Marchese, Lúcia Brandão, Sabrina Bernardez, Evandro Tinoco Mesquita, Nazareth N. Rocha, Antônio Cláudio Lucas da Nóbrega,

Fundamento: Pacientes com insuficiência cardíaca (IC) apresentam disfunção ventricular esquerda e redução da pressão arterial média (PAM).O aumento do estímulo adrenérgico causa vasoconstrição e resistência dos vasos, mantendo a PAM, enquanto aumenta a resistência vascular periférica e a rigidez dos vasos condutores.O aumento da pressão de pulso (PP) reflete a complexa interação do coração com os sistemas arteriais e venosos.O aumento da PP é um importante marcador de risco em pacientes com insuficiência ...

Tópico(s): Heart Failure Treatment and Management

2014 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Henrique Miller Balieiro, Raphael Kasuo Osugue, Samuel Pereira Rangel, Raphael Brandão, Tatiana Leal Balieiro, Sabrina Bernardez, Evandro Tinoco Mesquita,

data on heart failure (HF) in Brazil are ensued from tertiary centers. This information can not be extended to the rural population, for it reflects distinct social, economic and cultural characteristics.To establish the clinical and demographic profile and quality indicators for HF in rural areas.Transversal cohort study that included 166 patients from the rural area of Valença, Rio de Janeiro, Brazil. After the evaluation of clinical, laboratorial and echocardiograph data, chi-square and Fisher' ...

Tópico(s): Cardiac pacing and defibrillation studies

2009 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia