Produção Nacional
Revisado por pares
Átila Duque Rossi, João Locke Ferreira de Araújo, Tailah Bernardo de Almeida, Marcelo Ribeiro‐Alves, Camila de Almeida Velozo, Jéssica Maciel de Almeida, Isabela de Carvalho Leitão, Sâmila Natiane Ferreira, Jéssica da Silva Oliveira, Hugo José Alves, Helena Toledo Scheid, Débora S. Faffe, Rafael Mello Galliez, Renata Eliane de Ávila, Gustavo Gomes Resende, Mauro Martins Teixeira, Alice Laschuk Herlinger, Aliny dos Santos Carvalho, André F. Santos, Anna Carla Pinto Castiñeiras, Bianca Isabelle Barreto Teixeira, Bianca Ortiz da Silva, Bruno Clarkson, Bruno Eduardo Dematté, Camila Nacif, Camille Victória Leal Correia de Silva, Carolina Moreira Voloch, Caroline Macedo Nascimento, Carolyne Lalucha Alves L. da Graça, Cássia Cristina Alves Gonçalves, Cíntia Policarpo, Diana Mariani, Ekaterini Simões Goudouri, Elaine Sobral da Costa, Elisângela Silva, Enrico Bruno Riscarolli, Érica Ramos dos Santos Nascimento, Fabio Hecht Castro Medeiros, Fábio L. Monteiro, Fernanda Leitão dos Santos, Fernando Luz de Castro, Filipe Romero Rebello Moreira, Francine Bittencourt Schiffler, Gabriela Bergiante Kraychete, Gabriele Silveira da Cunha, Gisely Novaes Borges da Cunha, Guilherme S. Lira, Gustavo Peixoto Duarte da Silva, Harrison James Westgarth, Helena D.’Anunciação de Oliveira, Helena Keito Toma, Huang Fang, Inês Corrêa Gonçalves, Ingrid Camelo da Silva, Isabela Labarba Carvalho de Almeida, Joissy Aprigio de Oliveira, Juliana Cazarin de Menezes, Juliana T.S. Fortuna, Karyne Ferreira Monteiro, Kíssyla Harley Della Pascôa França, Laura Zalcberg Renault, Lendel Correia da Costa, Leticia Averbug Correa, Liane de Jesus Ribeiro, Lídia Theodoro Boullosa, Liliane Cavalcante, Luana dos Santos Costa, Lucas Matos Millioni, Luciana Jesus da Costa, Luiza M. Higa, Marcela dos Santos Durães, Marcelo Amaral de Souza, Marcelo Calado de Paula Tôrres, Mariana Freire Campos, Mariana Quinto, Mariane Talon de Menezes, Marisa Souza Correia, Mateus Rodrigues de Queiroz, Matheus Augusto Calvano Cosentino, Mayla Gabryele Miranda de Melo, Mirela D’arc Ferreira da Costa, Pedro Paz, Raíssa Mirella dos Santos Cunha da Costa, Raquel Fernandes Coelho, Richard Araújo Maia, Rodrigo Brindeiro, Romina Carvalho Ferreira, Sérgio Machado Lisboa, Thamiris dos Santos Miranda, Victor Akira Ota, Victoria Cortes Bastos, Viviane Guimarães Gomes, Orlando da Costa Ferreira Júnior, Terezinha Marta Pereira Pinto Castiñeiras, Renan P. Souza, Amílcar Tanuri, Renato Santana Aguiar, Shana Priscila Coutinho Barroso, Cynthia Chester Cardoso,
Abstract ACE2 and TMPRSS2 are key players on SARS-CoV-2 entry into host cells. However, it is still unclear whether expression levels of these factors could reflect disease severity. Here, a case–control study was conducted with 213 SARS-CoV-2 positive individuals where cases were defined as COVID-19 patients with respiratory distress requiring oxygen support (N = 38) and controls were those with mild to moderate symptoms of the disease who did not need oxygen therapy along the entire clinical course ( ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Felipe Hugo Alencar Fernandes, Rayanne Sales de Araújo Batista, Francinalva Dantas de Medeiros, Fábio S. Santos, Ana Cláudia Dantas de Medeiros,
The aim of this work was to develop and validate an analytical method for the identification of the chemical marker of Schinopsis brasiliensis Engl., Anacardiaceae. It would determine the total polyphenols and flavonoid content by spectrophotometric methodology in the dried extract of plant. The chromatographic profiles of S. brasiliensis were determined using HPLC-UV. The liquid chromatography method was conducted on a Phenomenex Gemini NX C18 column (250 × 4.6 mm, 5 μm). The mobile phase consisted ...
Tópico(s): Phytochemicals and Antioxidant Activities
2015 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Produção Nacional
Revisado por pares
João Vitor dos Santos Canellas, Rafael Cabral da Costa, Ricardo Caldeira Breves, Genilza Pereira de Oliveira, Carlos Marcelo Figueredo, Ricardo Guimarães Fischer, Alessandra Alves Thole, Paulo José Medeiros, Fabio Ritto,
The use of platelet concentrate in alveolar ridge preservation has been broadly studied. However, no randomized clinical trials with histomorphometric analysis and low risk of bias are available in the literature. We conducted a prospective, single-blind, parallel, randomized, controlled clinical trial to evaluate the efficacy of leukocyte- and platelet-rich fibrin (L-PRF) in socket preservation after tooth extraction. Additionally, the effect of L-PRF on bone formation was analyzed histologically ...
Tópico(s): Dental Radiography and Imaging
2019 - Elsevier BV | Journal of Cranio-Maxillofacial Surgery
Produção Nacional
Revisado por pares
Isabela dos Santos Paglione, Marcella Vitória Galindo, João Augusto Salviano de Medeiros, Fábio Yamashita, Izabela Dutra Alvim, Carlos Raimundo Ferreira Grosso, Lyssa Setsuko Sakanaka, Marianne Ayumi Shirai,
This work compared the effect of the addition of free oregano essential oil (OEO) and OEO microencapsulated by ionic gelation on the properties of soy protein concentrate (SPC) films. The films were evaluated by mechanical, barrier, morphological, antimicrobial and antioxidant properties. The incorporation of free OEO decreased the tensile strength and Young's modulus and increased the solubility of the films. These results may be related to the reduction of the polymer-polymer interaction, forming ...
Tópico(s): Microencapsulation and Drying Processes
2019 - Elsevier BV | Food Packaging and Shelf Life
Produção Nacional
Revisado por pares
Rafael Milani Medeiros, Fábio Duarte, Faris Achmad, Arman Jalali,
This paper discusses how information and communication technologies (ICT) may influence travel behavior of an informal transport system, and whether and in which ways merging digital technologies represents disruption for a specific sociotechnical ensemble. For decades, ojek has been a form of informal passenger transport, based on motorcycles in Jakarta, and recently smartphone apps have become available in that sociotechnical arrangement. We randomly surveyed passengers and drivers in the central ...
Tópico(s): COVID-19 Digital Contact Tracing
2018 - Taylor & Francis | Transportation Planning and Technology
Produção Nacional
Revisado por pares
Johnnatas Mikael Lopes, Gerônimo José Bouzas Sanchis, Jovany Luiz Alves de Medeiros, Fábio Galvão Dantas,
The study evaluated the trend of hospitalization for ischemic stroke (HIS) and its hospital mortality in Brazil over the last 15 years as well as the impact of the Hiperdia program in this scenario.An ecological study was designed with analytical approach and data collected in the Hospital Admission System on episodes of stroke, over the years 1998 to 2012. All data were stratified by sex and age, creating an indicator for HIS and proportion of hospital mortality. To estimate the trend of the data ...
Tópico(s): Health, Nursing, Elderly Care
2016 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
João Vitor dos Santos Canellas, Hugo Leonardo Mendes Barros, Paulo José Medeiros, Fabio Ritto,
The objective of this study was to evaluate, through cone beam computed tomography, the immediate changes in pharyngeal airway space (PAS) after orthognathic surgery in class III patients, and to determine the influence of surgery on the development of obstructive sleep apnoea hypopnoea syndrome (OSAHS). A prospective study was conducted; 33 patients were divided into three groups: mandibular setback surgery (nine patients), bimaxillary surgery (18 patients), and maxillary advancement surgery (six patients). ...
Tópico(s): Neuroscience of respiration and sleep
2016 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Produção Nacional
Revisado por pares
Raphael Castiglioni Coser, Helena Silveira, Paulo José Medeiros, Fabio Ritto,
The purpose of the present study was to evaluate the effectiveness of autologous blood injection in the treatment of recurrent temporomandibular joint dislocation. Eleven patients diagnosed with recurrent dislocation of the joint that could not be self-reduced, received bilateral injections of autologous blood in the superior joint compartment and pericapsular region. During a follow-up period ranging from 24 to 35 months (average 29.6 months), eight patients (72.7%) did not show new episodes of dislocation. ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2015 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Produção Nacional
Revisado por pares
João Vitor dos Santos Canellas, Hugo Leonardo Mendes Barros, Paulo José Medeiros, Fabio Ritto,
Tópico(s): Airway Management and Intubation Techniques
2015 - Springer Science+Business Media | Sleep And Breathing
Produção Nacional
Revisado por pares
Sérgio Queiroz de Medeiros, Fabio Mascarenhas, Roberto Ierusalimschy,
We present a semantics for left-recursive Parsing Expression Grammars.• A small extension adds precedence/associativity declarations to operator grammars.• We give a semantics for compilation of left-recursive PEGs to a parsing machine.• Our semantics are conservative: non-left-recursive PEGs are unaffected.
Tópico(s): Formal Methods in Verification
2014 - Elsevier BV | Science of Computer Programming
Maria Almerice Lopes da Silva, Cynthia Regina Pedrosa Soares, Rafael Acioli Medeiros, Zulma Medeiros, Fábio Lopes de Melo,
Conventional nested PCR is a very sensitive and specific method for the diagnosis of visceral leishmaniasis. However, this type of PCR is notorious for contamination problems related to the processing of the product between the first and the second PCR steps. In order to have a PCR method that is just as efficient but without the risk of contamination, we attempted the optimization of a single-tube nested PCR (STNPCR) method. During the first and the second PCR steps, we used the small subunit of ...
Tópico(s): Parasites and Host Interactions
2013 - Elsevier BV | Experimental Parasitology
Produção Nacional
Revisado por pares
Rafael Milani Medeiros, Fábio Duarte,
During the last 15 years an increasing number of presidents, prime ministers, governors and mayors in developed and developing countries have been riding bicycles to promote a more sustainable and friendly form of urban mobility. We believe that these images also reveal and influence the image of contemporary urban mobility – the way in which people see what urban mobility is and how it should be. In this paper we discuss how the image of the bicycle has changed in Brazil and how this may influence ...
Tópico(s): Physical Education and Sports Studies
2013 - Taylor & Francis | Urban Planning and Transport Research
Produção Nacional
Revisado por pares
Aracele Tenório de Almeida Cavalcanti, Zulma Medeiros, Fábio Lopes, Luiz Dias de Andrade, Valéria Ferreira, Vera Magalhães, Demócrito de Barros Miranda-Filho,
HIV/AIDS-associated visceral leishmaniasis may display the characteristics of an aggressive disease or without specific symptoms at all, thus making diagnosis difficult. The present study describes the results of diagnostic tests applied to a series of suspected VL cases in HIV-infected/AIDS patients admitted in referral hospitals in Pernambuco, Brazil. From a total of 14 eligible patients with cytopenias and/or fever of an unknown etiology, and indication of bone marrow aspirate, 10 patients were ...
Tópico(s): Trypanosoma species research and implications
2012 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
Produção Nacional
Revisado por pares
Edja Maria Melo de Brito Costa, Augusto Pierry de Araújo Evangelista, Ana Cláudia Dantas de Medeiros, Fábio Roberto Dametto, Rejane Andrade de Carvalho,
This in vitro study evaluated both the antimicrobial activity and the root canal cleaning ability of plant extracts used in irrigation solutions. The antimicrobial activities of the aroeira-da-praia (Schinus terebintifolius Raddi) and the quixabeira (Syderoxylum obtusifolium Roem & Schult) hydroalcoholic extracts, of 2.5% sodium hypochlorite (NaOCl) and of 0.12% chlorhexidine (positive control) against Enterococcus faecalis were tested with the agar well diffusion method. The level of root canal cleanliness ...
Tópico(s): Dental Anxiety and Anesthesia Techniques
2012 - Brazilian Society of Dental Research | Brazilian Oral Research
Produção Nacional
Revisado por pares
Cecilia H. Vallejos de Schatz, Henry Medeiros, Fábio Kurt Schneider, Paulo José Abatti,
This article analyzes wireless communication protocols that could be used in healthcare environments (e.g., hospitals and small clinics) to transfer real-time medical information obtained from noninvasive sensors. For this purpose the features of the three currently most widely used protocols—namely, Bluetooth® (IEEE 802.15.1), ZigBee (IEEE 802.15.4), and Wi-Fi (IEEE 802.11)—are evaluated and compared. The important features under consideration include data bandwidth, frequency band, maximum transmission ...
Tópico(s): Context-Aware Activity Recognition Systems
2012 - Mary Ann Liebert, Inc. | Telemedicine Journal and e-Health
Produção Nacional
Revisado por pares
Sérgio Queiroz de Medeiros, Fabio Mascarenhas, Roberto Ierusalimschy,
Most scripting languages nowadays use regex pattern-matching libraries. These regex libraries borrow the syntax of regular expressions, but have an informal semantics that is different from the semantics of regular expressions, removing the commutativity of alternation and adding ad-hoc extensions that cannot be expressed by formalisms for efficient recognition of regular languages, such as deterministic finite automata. Parsing Expression Grammars are a formalism that can describe all deterministic ...
Tópico(s): Algorithms and Data Compression
2012 - Elsevier BV | Science of Computer Programming
Produção Nacional
Revisado por pares
Juliana C. Castanha Zanoli, Marcos A. Maioli, Hyllana C. D. Medeiros, Fábio E. Mingatto,
Abamectin (ABA) is a macrocyclic lactone of the avermectin family used worldwide as an antiparasitic agent in farm animals and pets and as the active ingredient of insecticides and nematicides. In this study, the effects of abamectin on the bioenergetics of mitochondria isolated from rat liver were evaluated. Mitochondria are responsible for converting the energy released by electron transport and stored as the binding energy molecule ATP. Xenobiotics that interfere with its synthesis or utilization ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2011 - Elsevier BV | Toxicology in Vitro
Produção Nacional
Revisado por pares
Lia Carolina Soares Medeiros, Fabio M. Gomes, LUIS RENATO MAIA MACIEL, Sérgio Henrique Seabra, Roberto Docampo, Silvia N.J. Moreno, Helmut Plattner, Joachim Hentschel, Urara Kawazoe, Héctor Barrabin, Wanderley de Souza, Renato Augusto DaMatta, Kildare Miranda,
The structural organization of parasites has been the subject of investigation by many groups and has lead to the identification of structures and metabolic pathways that may represent targets for anti-parasitic drugs. A specific group of organelles named acidocalcisomes has been identified in a number of organisms, including the apicomplexan parasites such as Toxoplasma and Plasmodium, where they have been shown to be involved in cation homeostasis, polyphosphate metabolism, and osmoregulation. ...
Tópico(s): Helminth infection and control
2011 - Wiley | Journal of Eukaryotic Microbiology
Produção Nacional
Revisado por pares
Renata Jurema Medeiros, Fábio de Oliveira Monteiro, Gleice Castelo da Silva, Amary Nascimento Júnior,
Nos últimos anos, casos de intoxicação exógena de animais domésticos foram atendidos na Faculdade de Veterinária da Universidade Federal Fluminense (UFF). Sejam acidentais ou intencionais, esses casos ocorrem principalmente no ambiente doméstico e envolvem diferentes agentes tóxicos, tais como agrotóxicos, raticidas anticoagulantes, medicamentos, dentre outros. O presente trabalho objetivou realizar um estudo retrospectivo dos casos de intoxicação em cães e gatos atendidos na Faculdade de Veterinária ...
Tópico(s): Plant Toxicity and Pharmacological Properties
2009 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Manoel Januário da Silva Júnior, José Francismar de Medeiros, Fábio Henrique Tavares de Oliveira, Indalécio Dutra,
O melão produzido no estado do Rio Grande do Norte é cultivado sob irrigação e fertirrigação. Com o uso da fertirrigação e o conhecimento das curvas de absorção de nutrientes, é possível parcelar a dose total dos nutrientes em várias aplicações, durante o ciclo da cultura. Com o exposto, objetivou-se obter curvas de acúmulo de matéria seca e a absorção de nitrogênio, fósforo, potássio, cálcio e magnésio pelo meloeiro "pele-de-sapo" e determinar a extração total desses nutrientes no final do ciclo ...
Tópico(s): Growth and nutrition in plants
2006 - UNIVERSIDADE FEDERAL DE CAMPINA GRANDE | Revista Brasileira de Engenharia Agrícola e Ambiental
R. M. B. Moreno, Eliton S. Medeiros, Fábio Cop Ferreira, Neri Alves, P.S. Gonçalves, L. H. C. Mattoso,
The thermal degradation behaviour of rubber from six new Hevea brasiliensis clones (IAC 40, 56, 300, 301, 302 and 303) from São Paulo State, Brazil was studied by thermogravimetry using the Flynn–Wall–Ozawa approach to assess the kinetic parameters (reaction order, activation energy and pre-exponential factor) of the decomposition process. This study indicated that the thermal behaviour is a complex multiple step process, which depends on the type of rubber Hevea clones studied. The rubber from these ...
Tópico(s): Polymer crystallization and properties
2006 - Taylor & Francis | Plastics Rubber and Composites Macromolecular Engineering
Produção Nacional
Revisado por pares
Nilton César Fiedler, Isaac Nuno Carvalho de Azevedo, Alba Valéria Rezende, Marcelo Brilhante de Medeiros, Fábio Venturoili,
O objetivo desta pesquisa foi avaliar o efeito do fogo na estrutura e composição florística de uma área de 10 ha de cerrado sensu stricto, localizada na fazenda Água Limpa da Universidade de Brasília. Foram realizados dois inventários, sendo o primeiro em 1999, logo após a área ter sido totalmente queimada, devido a um incêndio criminoso, e o segundo em novembro de 2002. Quatro parcelas de 0,1 ha (20 x 50 m) foram tomadas, aleatoriamente, na área queimada. Todos os indivíduos lenhosos arbóreos vivos, ...
Tópico(s): Environmental and biological studies
2004 - Sociedade de Investigações Florestais | Revista Árvore
Produção Nacional
Revisado por pares
Wladimir Musetti Medeiros, Fábio Augusto de Luca, Alcides R. de Figueredo Júnior, Felipe Augusto Rodrigues Mendes, Carlos Gun,
Summary Heart rate recovery (HRR) is a strong mortality predictor. Exercise training (ET) and β‐blocker therapy have significant impact on the HRR of patients following myocardial infarction (MI). However, the combination of ET and β‐blocker therapy, as well as its effectiveness in patients with a more compromised HRR (≤12 bpm), has been under‐studied. Male patients ( n = 64) post‐MI were divided: Training + β‐blocker ( n = 19), Training ( n = 15), β‐blocker ( n = 11) and Control ( n = 19). Participants performed an ergometric ...
Tópico(s): Cardiovascular and exercise physiology
2017 - Wiley | Clinical Physiology and Functional Imaging
Produção Nacional
Revisado por pares
Cleitiane da Costa Nogueira, Carlos Eduardo de Araújo Padilha, Júlia Maria de Medeiros Dantas, Fábio Gonçalves Macêdo de Medeiros, Alexandre A. Guilherme, Domingos Fabiano de Santana Souza, Everaldo Silvino dos Santos,
Tópico(s): Enzyme Catalysis and Immobilization
2021 - Elsevier BV | Renewable Energy
Produção Nacional
Revisado por pares
Ademir Sérgio Ferreira de Araújo, Ana Roberta Lima Miranda, Arthur Prudêncio de Araújo Pereira, Wanderley José de Melo, Vânia Maria Maciel Melo, Sabrina Hermelindo Ventura, Eudemio Sousa Brito, Érika Valente de Medeiros, Fábio Fernando de Araújo, Lucas William Mendes,
Chromium (Cr) contamination can affect microorganisms in the soil, but the response of the microbial community in the rhizosphere of plants grown in Cr-contaminated soils is poorly understood. Therefore, this study assessed the microbial community, by amplicon sequencing, in the rhizosphere of maize and cowpea growing in uncontaminated (∼6.0 mg kg-1 Cr) and Cr-contaminated soils (∼250 mg kg-1 Cr). Comparing Cr-contaminated and uncontaminated soils, the microbial community in the maize rhizosphere clustered ...
Tópico(s): Microbial Community Ecology and Physiology
2022 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
P.M. Silva, J.N.O. Silva, Bruce Ramos Menezes Silva, Gustavo Ramos Salles Ferreira, Wyndly Daniel Cardoso Gaião, Miguel Villoria Recio, Gabriel Gazzoni Araújo Gonçalves, Cláudio Gabriel Rodrigues, Paloma Lys de Medeiros, Fábio André Brayner, Luiz Carlos Alves, M. Larsen, Hanne Ingmer, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva,
Aims To investigate the effects of the lectin from Punica granatum sarcotesta (PgTeL) on growth, viability, cell structure, biofilm formation and chitinase activity of Listeria monocytogenes. In addition, the effect of PgTeL on the adhesion and invasion of human cells (HeLa) was determined. Methods and Results PgTeL showed bacteriostatic and bactericidal effects on the strains L. monocytogenes N53-1 and EGD-e, causing morphometric alterations, cell aggregation, strong deformation and cell disruption. ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Oxford University Press | Journal of Applied Microbiology
Produção Nacional
Revisado por pares
Raquel Bueno Medeiros, Fábio Ramôa Pires, Alpdoğan Kantarcı, Jonas Capelli,
ABSTRACT Objectives: To analyze histologic findings of bone remodeling at the time of surgery and 90 days later at corticotomized and noncorticotomized sites. Materials and Methods: Eight adult patients with bilaterally inclined mandibular molars were included in this split-mouth study. Corticotomy was performed on the test side, and bone was harvested on both mandibular hemi-arches. Bone blocks were shipped to Forsyth Institute lab (Boston, Mass). After surgery, cantilevers were activated to upright ...
Tópico(s): dental development and anomalies
2017 - E.H Angle Education and Research Foundation | The Angle Orthodontist
Produção Nacional
Revisado por pares
Diego Moreira de Souza, Sabrina Medeiros Suita, Fábio Pereira Leivas Leite, Luís Alberto Romano, Wilson Wasielesky, Eduardo Luís Cupertino Ballester,
... more papers by this authorSabrina Medeiros Suita, Sabrina Medeiros Suita Laboratório de Maricultura, Instituto de Oceanografia, Universidade Federal do Rio Grande (FURG), Rio Grande (RS), BrasilSearch for more papers by this authorFabio Pereira Leivas Leite, Fabio Pereira Leivas Leite Laboratório de Microbiologia, Universidade Federal ... more papers by this authorSabrina Medeiros Suita, Sabrina Medeiros Suita Laboratório de Maricultura, Instituto de Oceanografia, Universidade Federal do Rio Grande (FURG), Rio Grande (RS), BrasilSearch for more papers by this authorFabio Pereira Leivas Leite, Fabio Pereira Leivas Leite Laboratório de Microbiologia, Universidade Federal ...
Tópico(s): Aquatic life and conservation
2011 - Wiley | Aquaculture Research
Ana T. Freitas, Conceição Calhau, Gonçalo Antunes, Beatriz Araújo, Matilde Bandeira, Sofia Barreira, Filipa Bazenga, Sandra Bráz, Daniel Caldeira, Susana Constantino Rosa Santos, Ana Faria, Daniel Faria, Marta Fraga, Beatriz Nogueira-Garcia, Lucia Gutheil Gonçalves, П. Н. Ковальчук, Luísa Lacerda, Hugo Lopes, Daniel Luís, Fábio Medeiros, Ana M. P. Melo, José Melo‐Cristino, Ana Luísa P. Miranda, Clara Pereira, Ana Teresa Pinto, João Viana Pinto, Helena Proença, Angélica Ramos, João P. R. Rato, Filipe Rocha, Júlio César Rocha, André Moreira-Rosário, Helena Vazão, Yuliya Volovetska, João Tiago Guimarães, Fausto J. Pinto,
Abstract Vitamin D is a fundamental regulator of host defences by activating genes related to innate and adaptive immunity. Previous research shows a correlation between the levels of vitamin D in patients infected with SARS-CoV-2 and the degree of disease severity. This work investigates the impact of the genetic background related to vitamin D pathways on COVID-19 severity. For the first time, the Portuguese population was characterized regarding the prevalence of high impact variants in genes ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Nature Portfolio | Scientific Reports
Joana Simões, Ana Rita Ferreira, Pedro Martins Almeida, Frederico Trigueiros, Armando Braz, João R. Inácio, Fábio Medeiros, Sandra Bráz, António Pais de Lacerda,
Organizing pneumonia (OP) is a sub-acute process of pulmonary tissue repair secondary to lung injury, defined histopathologically by intra-alveolar buds of granulation tissue within the lumen of distal pulmonary airspaces. It can be either cryptogenic or secondary (SOP) to different clinical conditions, namely infections. Despite being nonspecific, its diagnosis can be made by the association of clinical and imaging criteria. We report two cases of OP associated to SARS-CoV-2 pneumonia, admitted at ...
Tópico(s): COVID-19 diagnosis using AI
2021 - Elsevier BV | Respiratory Medicine Case Reports