Aysun Degirmenci, Ömer Sonkaya, Caner Soylukan, Tuğçe Karaduman, Fatih Algı,
We disclose an interesting concept for developing heavy atom-free chemiluminogenic photosensitizers. To accomplish this, conjugates 2 and 3, which are composed of boron-dipyrromethene (BODIPY) and 2,3-dihydrophthalazine-1,4-dione units, are investigated. 2 and 3 are compared in terms of their photophysical properties, chemiluminescence responses, and singlet oxygen production. Strikingly, the results indicate that decoration of BODIPY with the 2,3-dihydrophthalazine-1,4-dione scaffold boosts the ...
Tópico(s): Photodynamic Therapy Research Studies
2021 - American Chemical Society | ACS Applied Bio Materials
Deniz Emre, Nuray Denizhan, Dilsat Ozkan‐Ariksoysal, Ali̇ Bi̇li̇ci̇, Ömer Sonkaya, Fatih Algı, Selehattin Yılmaz,
A novel graphene quantum dots (GQD) / polyfluorene (PF) nanocomposite was deposited on the disposable pencil tip graphite electrode (PGE) and proven to be an efficient nanosensor for analysis of the electrochemical interaction between the antitumor compound mitomycin C (MC) with double stranded DNA (ds-DNA). This modified electrode (GQD@PF-PGE) was prepared in four steps: hydrothermal, chemical oxidation, ultrasonication and electro-oxidation processes. GQD, PF, GQD@PF and GQD@PF-PGE have been characterized ...
Tópico(s): Molecular Sensors and Ion Detection
2023 - Elsevier BV | Materials Science and Engineering B
Caner Soylukan, Melek Pamuk Algı, Fatih Algı, Ömer Sonkaya,
Abstract: Aza-boron-dipyrromethenes (Aza-BODIPYs) represent an important class of chromo-phores absorbing and emitting in the near-infrared (NIR) region. They have unique optical and elec-tronic features and higher physiological and photo stability than other NIR dyes. Especially after the development of facile synthetic routes, Aza-BODIPYs have become indispensable fluors that can find various applications ranging from chemosensors, bioimaging, phototherapy, solar energy materials, photocatalysis, ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2022 - Bentham Science Publishers | Current Organic Synthesis
Ali Rıza Sonkaya, Mehmet Güney Şenol, Serkan Demir, Fatih Özdağ,
Tópico(s): Transcranial Magnetic Stimulation Studies
2015 - Springer Science+Business Media | Acta Neurologica Belgica
Alihan Toksoy, Ömer Sonkaya, Dilek Sadife Erkan, Rukiye Boran Gulen, Melek Pamuk Algı, Fatih Algı,
Photodynamic therapy (PDT) is a method for the treatment of cancer. Furthermore, PDT can also be used for the eradication of bacteria. The photo-sensitizing drug, a.k.a photosensitizer, is critical for the success of PDT. Although norsquaraines are analogs of squaraine dyes, they are overlooked as photosensitizers.In this work, synthesis, characterization, bioimaging and in vitro PDT applications of a new norsquaraine dye 1 were described. We also prepared nanoparticles from norsquaraine 1 and Pluronic ...
Tópico(s): Porphyrin and Phthalocyanine Chemistry
2022 - Elsevier BV | Photodiagnosis and Photodynamic Therapy
Ömer Sonkaya, Şeyma Ocakçı, Alihan Toksoy, Melek Pamuk Algı, Fatih Algı,
Herein we describe the facile synthesis of new N-doped carbon nanoparticles (CNPs) obtained from 1,10-phenanthroline by the solvothermal method. Characterization of CNPs were carried out with transmission electron microscope (TEM), X-ray photoelectron spectra (XPS), Fourier transform infrared spectra (FTIR), UV-vis absorption spectra, and luminescence spectra. CNPs were pH sensitive and exploited as fluorescent chemosensors and imaging agents for Al(III) and Zn(II) ions in real-life samples. Remarkably, ...
Tópico(s): Electrochemical Analysis and Applications
2023 - Elsevier BV | Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
Serkan Demir, Erdem Toğrol, Fatih Özdağ, Ali Rıza Sonkaya,
Objective: In this study the factors that trigger the seizures in epileptic patients over the age of 50 was investigated and the frequency of seizures was analyzed regarding different age, gender, type of seizure and etiological groups. Background: For this purpose, 387 patients were included in the study who were admitted to neurology outpatient clinic with the diagnosis of epilepsy. Methods: The patients are divided into groups based on those characteristics: male / female, generalized seizure / partial ...
Tópico(s): Epilepsy research and treatment
2015 - Lippincott Williams & Wilkins | Neurology
Serkan Demir, Erdem Toğrol, Ali Rıza Sonkaya, Mustafa Tansel Kendırlı, Semih Alay, Tugba Yanar Celik, Şakir Delil, Fatih Özdağ,
Objective:In this study the factors that trigger the seizures in epileptic patients over the age of 50 was investigated and the frequency of seizures was analyzed regarding different age, gender, type of seizure and etiological groups. Method: For this purpose, 387 patients were included in the study who were admitted to neurology outpatient clinic with the diagnosis of epilepsy. The patients are divided into groups based on those characteristics: male / female, generalized seizure / partial seizure, ...
Tópico(s): Metabolism and Genetic Disorders
2015 - | Medical Science and Discovery
Serkan Demir, Erdem Toğrol, Ali Rıza Sonkaya, Mustafa Tansel Kendırlı, Semih Alay, Tugba Yanar Celik, Şakir Delil, Fatih Özdağ,
Tópico(s): Diet and metabolism studies
2016 - | Medical Science and Discovery
Fatih Algı, Melek Pamuk Algı, Ömer Sonkaya, Şeyma Ocakçı,
Tópico(s): Advanced biosensing and bioanalysis techniques
2024 - Elsevier BV | Dyes and Pigments