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Artigo Acesso aberto Revisado por pares

Sulaiman Lakoh, Joseph Sam Kanu, Sarah Conteh, James B.W. Russell, Stephen Sevalie, Christine Ellen Elleanor Williams, Umu Barrie, Aminata Kadie Kabia, Fatmata Conteh, Mohamed Jalloh, Gibrilla F. Deen, Mustapha Kabba, Aiah Lebbie, Ibrahim Franklyn Kamara, Bobson Derrick Fofanah, Anna Maruta, Christiana Kallon, Foday Sahr, Mohamed Samai, Olukemi Adekanmbi, Yi Le, Xuejun Guo, Rugiatu Z. Kamara, Darlinda F. Jiba, Joseph Okeibunor, George A. Yendewa, Emmanuel Firima,

Despite the impact of inappropriate prescribing on antibiotic resistance, data on surgical antibiotic prophylaxis in sub-Saharan Africa are limited. In this study, we evaluated antibiotic use and consumption in surgical prophylaxis in 4 hospitals located in 2 geographic regions of Sierra Leone.We used a prospective cohort design to collect data from surgical patients aged 18 years or older between February and October 2021. Data were analyzed using Stata version 16 software.Of the 753 surgical patients, ...

Tópico(s): Surgical site infection prevention

2022 - Cambridge University Press | Antimicrobial Stewardship & Healthcare Epidemiology

Artigo

David Ishola, Daniela Manno, Muhammed O. Afolabi, Babajide Keshinro, Viki Bockstal, Baimba Rogers, Kwabena Owusu-Kyei, Alimamy Serry-Bangura, Ibrahim Swaray, Brett Lowe, Dickens Kowuor, Frank Baiden, Thomas A. Mooney, Elizabeth Smout, Brian Köhn, Godfrey T Otieno, Morrison Jusu, Julie Foster, Mohamed Samai, Gibrilla F. Deen, Heidi J. Larson, Shelley Lees, Neil Goldstein, Katherine E. Gallagher, Auguste Gaddah, Dirk Heerwegh, Benoît Callendret, Kerstin Lühn, Cynthia Robinson, Maarten Leyssen, Brian Greenwood, Macaya Douoguih, Bailah Leigh, Deborah Watson‐Jones, M Kargbo, E Bockarie, N L James, A Kabbah, A Kamara, Kellie Koroma, S O Langley, N William, R Kessebeh, Thomas A. Mooney, Lansana Conteh, Elizabeth Smout, K Allieu, K Bangura, Mohamed Bangura, M A Bangura, H Jalloh, Abdulai Jalloh, Ibrahim Franklyn Kamara, M Kamara, A Konteh, S Koroma, C Marrah, Mohamed Sesay, Mohamed Sesay, A T Deen, Abdulai Tejan Jalloh, R M Kaimbay, David Kain, A Kamara, E L Kamara, M Kamara, Osman Kamara, Ibrahim Franklyn Kamara, Samuel Kamara, M Kanneh, Alusine H. Koroma, D Lahai, I S Mansaray, W S Marah, Massah Massaquoi, A Nabie, N S Saidu, I Samai, J N Tengheh, A S Turay, A Fornah, Fatmata Sesay, A Sow, E Swaray, F Mansaray, T Ade-Cole, Lamin Molecule Bangura, M L Conteh, A Kabbah, Adama Koroma, Mohamed Koroma, Amy Sam, T Scott, T Sessie, J-H C Sunders, Samuel Turay, J Weekes, Mahmud Sheku, Laura Gibson, Dickens Kowuor, Imthiaz Ahamed, W Allieu, D U Kabba, Fatmata Kamara, M S Kebbie, M Pessima, Alie Wurie, Fatoumata Bah, A Bangura, Rohey Bangura, L Blango, S Boima, M Conteh, Y Conteh, M L Daramy, O Fofanah, Elizabeth C. George, T F Hanson, M I Jalloh, M Kalawa, A M Kamara, F E Kamara, G M Kamara, H M Kamara, P. Kamara, R Kamara, R Kamara, D P Kanneh, M Kanneh, I Komeh, Mohamed Koroma, M Kuyateh, F F Mansaray, M M Mansaray, A B Sillah, M A Tarawally, O S Turya, J B Yawmah, Bailah Leigh, Deborah Watson‐Jones, Brian Greenwood, Mohamed Samai, Gibrilla F. Deen, Dennis Marke, Peter Piot, Peter G. Smith, John Edmunds, Shelley Lees, Heidi J. Larson, Helen A. Weiss, P Wilson, Cathy Maxwell, David Ishola, Muhammed O. Afolabi, Frank Baiden, Pauline Akoo, Kwabena Owusu-Kyei, Daniel Tindanbil, Hilary Bower, J Stuart, Osman Bah, Baimba Rogers, Alimamy Serry-Bangura, Ibrahim Swaray, A Bangura, I J David, Deborah Davies, J A Kallon, A Kamara, Ibrahim Franklyn Kamara, Michael Kamara, Foday Morovia, F Suma, F Thompson, M Murray, Fatmata Sesay, Ibrahim Juldeh Sesay, O Kakay, F Suma, Julie Foster, R. Philips, Daniela Manno, K Gallager, Stephanie Cox, Natasha Howard, Mansur Cesay, P Torrani, Suresh D. Sharma, E Snowden, T. Banks, T Harber, Joelle Brown, Kirsten Howard, N Melton, S Malcolm, Sabrina Welsh, Rosalind M. Eggo, Mario Jendrossek, Carl A. B. Pearson, Johan Van Hoof, Macaya Douoguih, K Offergelt, Cynthia Robinson, Babajide Keshinro, M Van Alst, Neal Mahajan, Viki Bockstal, Neil Goldstein, Auguste Gaddah, Dirk Heerwegh, Kerstin Lühn, Maarten Leyssen, Brett Lowe, Ken Awuondo, Hannah Hafezi, Emma Hancox, Brian Köhn, G O Tuda, F Koroma, A Kamara, G Bangura, Mattu Tehtor Kroma, L Fofanah, A Pessima, M Rogers, O Sheriff, T W Ajala, J Fangawa, S Foday, I Jabbie, B Mansaray, H A Mansaray, K Sesay, M K Charles, P C Heroe, M Lamin Karbo, I S Yansaneh, Seth Gogo Egoeh, A Trye, Monica Amponsah, N D Alghali, Abdulai Jawo Bah, I Bangura, Abosede Cole, K Fofanah, S Fofanah, H Jalloh, K F N Jalloh, N Jalloh, H U Kabba, Juana Kabba, M Kabba, R Kamara, Jennifer Kamara, F Kanjie, Alpha Kanu, Iynnah Kargbo, G Kassa-Koroma, S Koroma, Abdul J. Sankoh, T Sankoh, Osman Sesay, H Wilhem, C Theodore Williams, I Bangura, Y Ben-Rogers, Abdulai Tejan Jalloh, F J Jamboria, Nicholas Kamara, I Kanawah, A T Kargbo, Ibrahim Swaray, L Amara, I Bundu, H B Jakema, Kassim Kamara, Mahmud Sheku, Qadri Adebayo Adeleye, I Akhigbe, R Bakalemwa, Nathalie Chami, Tammy Sylvester, L Altmann, Bomposseh Kamara, Karel Van Roey, P Conteh, Masaru Samura, V Gandie, M Marrah, E Moinina, J Kalokoh, Musa Bangura, Sam Bosompem, Trudi Hilton, Morrison Jusu, P Borboh,

Background The Ebola epidemics in west Africa and the Democratic Republic of the Congo highlight an urgent need for safe and effective vaccines to prevent Ebola virus disease. We aimed to assess the safety and long-term immunogenicity of a two-dose heterologous vaccine regimen, comprising the adenovirus type 26 vector-based vaccine encoding the Ebola virus glycoprotein (Ad26.ZEBOV) and the modified vaccinia Ankara vector-based vaccine, encoding glycoproteins from Ebola virus, Sudan virus, and Marburg ...

Elsevier BV

Artigo

Muhammed O. Afolabi, David Ishola, Daniela Manno, Babajide Keshinro, Viki Bockstal, Baimba Rogers, Kwabena Owusu-Kyei, Alimamy Serry-Bangura, Ibrahim Swaray, Brett Lowe, Dickens Kowuor, Frank Baiden, Thomas A. Mooney, Elizabeth Smout, Brian Köhn, Godfrey T Otieno, Morrison Jusu, Julie Foster, Mohamed Samai, Gibrilla F. Deen, Heidi J. Larson, Shelley Lees, Neil Goldstein, Katherine E. Gallagher, Auguste Gaddah, Dirk Heerwegh, Benoît Callendret, Kerstin Lühn, Cynthia Robinson, Brian Greenwood, Maarten Leyssen, Macaya Douoguih, Bailah Leigh, Deborah Watson‐Jones, M Kargbo, E Bockarie, N L James, A Kabbah, A Kamara, Kellie Koroma, S O Langley, N William, R Kessebeh, Thomas A. Mooney, Lansana Conteh, Elizabeth Smout, K Allieu, K Bangura, Mohamed Bangura, M A Bangura, H Jalloh, Abdulai Jalloh, Ibrahim Franklyn Kamara, M Kamara, A Konteh, S Koroma, C Marrah, Mohamed Sesay, Mohamed Sesay, A T Deen, Abdulai Tejan Jalloh, R M Kaimbay, David Kain, A Kamara, E L Kamara, M Kamara, Osman Kamara, Ibrahim Franklyn Kamara, Samuel Kamara, M Kanneh, Alusine H. Koroma, D Lahai, I S Mansaray, W S Marah, Massah Massaquoi, A Nabie, N S Saidu, I Samai, J N Tengheh, A S Turay, A Fornah, Fatmata Sesay, A Sow, E Swaray, F Mansaray, T Ade-Cole, Lamin Molecule Bangura, M L Conteh, A Kabbah, Adama Koroma, Mohamed Koroma, Amy Sam, T Scott, T Sessie, J-H C Sunders, Samuel Turay, J Weekes, Mahmud Sheku, Laura Gibson, Dickens Kowuor, Imthiaz Ahamed, W Allieu, D U Kabba, Fatmata Kamara, M S Kebbie, M Pessima, Alie Wurie, Fatoumata Bah, A Bangura, Rohey Bangura, L Blango, S Boima, M Conteh, Y Conteh, M L Daramy, O Fofanah, Elizabeth C. George, T F Hanson, M I Jalloh, M Kalawa, A M Kamara, F E Kamara, G M Kamara, H M Kamara, P. Kamara, R Kamara, R Kamara, D P Kanneh, M Kanneh, I Komeh, Mohamed Koroma, M Kuyateh, F F Mansaray, M M Mansaray, A B Sillah, M A Tarawally, O S Turya, J B Yawmah, Bailah Leigh, Deborah Watson‐Jones, Brian Greenwood, Mohamed Samai, Gibrilla F. Deen, Dennis Marke, Tom Sesay, Peter Piot, Peter G. Smith, John Edmunds, Shelley Lees, Heidi J. Larson, Helen A. Weiss, P Wilson, R Phillips, Cathy Maxwell, David Ishola, Muhammed O. Afolabi, Frank Baiden, Pauline Akoo, Kwabena Owusu-Kyei, Daniel Tindanbil, Hilary Bower, J Stuart, Osman Bah, Baimba Rogers, Alimamy Serry-Bangura, Ibrahim Swaray, A Bangura, I J David, Deborah Davies, J A Kallon, A Kamara, Ibrahim Franklyn Kamara, Michael Kamara, Foday Morovia, F Suma, F Thompson, M Murray, Fatmata Sesay, O Kakay, F Suma, Ibrahim Juldeh Sesay, Julie Foster, R Phillips, Daniela Manno, Katherine E. Gallagher, Stephanie Cox, Natasha Howard, Mansur Cesay, P Torrani, Suresh D. Sharma, E Snowden, T. Banks, T Harber, Joelle Brown, Kirsten Howard, N Melton, S Malcolm, Sabrina Welsh, Rosalind M. Eggo, Mario Jendrossek, Carl A. B. Pearson, Kim Offergeld, C Ferrault, M Van Alst, Neal Mahajan, M. Van Looveren, S Van Ballaert, Tinne De Cnodder, N.J. Grobler, La Roza, T Liberi, L Armishaw, Christie P.M. Verkleij, Tracy Henrick, Aleksandra Banaszkiewicz, Brett Lowe, Ken Awuondo, Hannah Hafezi, Emma Hancox, Brian Köhn, G O Tuda, A Kamara, G Bangura, Mattu Tehtor Kroma, L Fofanah, A Pessima, M Rogers, O Sheriff, T W Ajala, J Fangawa, S Foday, Ibrahim Koroma, B Mansaray, H A Mansaray, K Sesay, M K Charles, P C Heroe, M Lamin Karbo, I S Yansaneh, Seth Gogo Egoeh, A Trye, Monica Amponsah, Lori Donelson, Tammy Sylvester, Victorine Owira, G Onyuka, L Nambuchi, Amos Oburu, Duncan Apollo, Lahai Vandi, N D Alghali, Abdulai Jawo Bah, I Bangura, Abosede Cole, S Fofanah, H Jalloh, K F N Jalloh, N Jalloh, H U Kabba, Juana Kabba, M Kabba, R Kamara, Jennifer Kamara, F Kanjie, Alpha Kanu, Iynnah Kargbo, G Kassa-Koroma, S Koroma, Abdul J. Sankoh, T Sankoh, Osman Sesay, H Wilhem, C T Williams, I Bangura, Y Ben-Rogers, Abdulai Tejan Jalloh, F J Jamboria, Nicholas Kamara, I Kanawah, A T Kargbo, Ibrahim Swaray, L Amara, I Bundu, H B Jakema, Kassim Kamara, Mahmud Sheku, Qadri Adebayo Adeleye, I Akhigbe, R Bakalemwa, Nathalie Chami, Tammy Sylvester, L Altmann, Bomposseh Kamara, Karel Van Roey, P Conteh, Masaru Samura,

Background Children account for a substantial proportion of cases and deaths from Ebola virus disease. We aimed to assess the safety and immunogenicity of a two-dose heterologous vaccine regimen, comprising the adenovirus type 26 vector-based vaccine encoding the Ebola virus glycoprotein (Ad26.ZEBOV) and the modified vaccinia Ankara vector-based vaccine, encoding glycoproteins from the Ebola virus, Sudan virus, and Marburg virus, and the nucleoprotein from the Tai Forest virus (MVA-BN-Filo), in a ...

Elsevier BV

Artigo

E Choi, Boris Lacarra, Muhammed O. Afolabi, Boni Maxime Ale, Frank Baiden, Christine Bétard, Julie Foster, Benjamin Hamzé, Christine Schwimmer, Daniela Manno, Éric D’Ortenzio, David Ishola, Cheick Mohamed Keita, Babajide Keshinro, Yusupha Njie, Wim van Dijck, Auguste Gaddah, Dickson Anumendem, Brett Lowe, Renaud Vatrinet, Bolarinde Lawal, Godfrey T Otieno, Mohamed Samai, Gibrilla F. Deen, Ibrahim Swaray, A Kamara, Michael Kamara, Mame Aminata Diagne, Dickens Kowuor, Chelsea McLean, Bailah Leigh, Abdoul Habib Béavogui, Maarten Leyssen, Kerstin Lühn, Cynthia Robinson, Macaya Douoguih, Brian Greenwood, Rodolphe Thiébaut, Deborah Watson‐Jones, Thomas A. Mooney, Lansana Conteh, M A Bangura, M A Bangura, H Jalloh, Ibrahim Franklyn Kamara, M Kamara, S Koroma, Mohamed Sesay, Mohamed Sesay, A T Deen, A Kamara, E L Kamara, Samuel Kamara, Alusine H. Koroma, I S Mansaray, Massah Massaquoi, A Nabie, Dickens Kowuor, Yusupha Njie, Lazarus Odeny, Mahmud Sheku, Abdulai Jalloh, Amadou Sow, E Swaray, F Mansaray, T Sessie, J-HC Sunders, Samuel Turay, J Weekes, M Pessima, Alie Wurie, M Conteh, M I Jalloh, P. Kamara, D P Kanneh, M Kanneh, I Komeh, Mohamed Koroma, M Kuyateh, F F Mansaray, Bailah Leigh, Deborah Watson‐Jones, Mohamed Samai, Gibrilla F. Deen, Tom Sesay, Peter Piot, Brian Greenwood, Shelley Lees, Heidi J. Larson, Muhammed O. Afolabi, David Ishola, Frank Baiden, Farba Faye, Daniel Tindanbil, Michael Kamara, Ibrahim Swaray, A Bangura, A M Kamara, Foday Morovia, J A Kallon, M Murray, Fatmata Sesay, F Suma, Ibrahim Juldeh Sesay, Eunji Choi, Daniela Manno, Julie Foster, Raphael Rwezaula, I Akhigbe, H Adetola, Bomposseh Kamara, Brett Lowe, Bola Lawal, Brian Köhn, G O Tuda, F Koroma, A Kamara, G Bangura, Mattu Tehtor Kroma, L Fofanah, A Pessima, M Rogers, O Sheriff, J Fangawa, S Foday, I Jabbie, H A Mansaray, K Sesay, H B Jakema, Mahmud Sheku, K F N Jalloh, M Kabba, F Kanjie, Alpha Kanu, G Kassa-Koroma, Morrison Jusu, Bockarie Koroma, P Borboh, A Kallon, Karel Van Roey, P Conteh, Masaru Samura, V Gandie, M Marrah, J Kalokoh, M A Bangura, Nicholas E. Connor, S. N. A. Saidu, A S Turay, A Lahai, Johnson Cl, D B Kogba, W S Wong Vincent, Musa Bangura, Angus Fayia Tengbeh, K Bangura, R Kabia, AM Nyakoi, S Lee, D Nyaberi, S Ndingi, L Nyallay, A Bangura, Baimba Idriss, M Sillah, Wilma Mackay, Tamar Murray, Joseph Edem-Hotah, T Fatorma, M Kamara, Sheriff Bangura, E Bonnie, M Sannoh, S Malcolm, Joelle Brown, E Snowden, Kirsten Howard, Arnold Adimabua Ojugo, C Massin-Shepherd, Abdoul Habib Béavogui, C Keita, Oumou Camara, JPY GUILAVOGUI, Houssaïnatou Bah, MA SAMOURA, Dally Muamba, B SEMAKUBA, Alimou Camara, A. Kaba, Marion Bérerd-Camara, Marcel Yaradouno, Marie Déchenaud, Mamadou Camara, Jacqueline Tambalou, Mihai Ștefan Cristian Haba, Sona Diallo, A Thea, Naman Doumbouya, M. S. Fofana, Mariam Beavogui, Alimou Camara, JT BEAVOGUI, Waly Diouf, Augustin Augier, Eric Barte de Sainte Fare, Billy Sivahera Muyisa, Sani Sayadi, Renaud Vatrinet, Benjamin Hamzé, Boris Lacarra, Éric D’Ortenzio, Boni Maxime Ale, Christine Bétard, Laura Richert, Davy Oulaï, Myriam Kanté, A-A SOUTTHIPHONG, Christine Schwimmer, Rodolphe Thiébaut, Anton Ottavi, Sandrine Couffin‐Cadiergues, Hélène Esperou, Shengwu Chai, Werner Buth, Kim Offergeld, A Menten, Niina Hammoud, S. de Ridder, Rita Sellecchia, Ronald in ‘t Veld, N Fogap, Dickson Anumendem, Helen Stapleton, Tom Reijns, Julie Haydon, Len Roza, B. Sawyer, Syed T. Hoda, JoAnn L. Yee, Tinne De Cnodder, Ellen Hubin, L Telen, Jayesh Desai, M Bennet, Maciej Pawłowski, Noortje van Gils, Nele Boeykens, Anna Kwaśniak, Marjolein A. P. Ligthart, Griet Van Roey, Elisa Fernández‐Millán, Auguste Gaddah, Wim van Dijck, S Jingshuang, S Randrasana, Cassandra Artis, A. J. Akinbinu, A Poretti, S Van Ballaert, Margaret Harris, M. Van Looveren, Paul Brandt, Cynthia Robinson, Viki Bockstal, Chelsea McLean, Isabella Versteege, C Ferrault, Artur Kamiński, Hans Vergauwen, CI Kerama, M Bennet, CA Forcheh, N Fogap, CV DiMondi, Laura S Stewart, John Meurer, A Beounitis, Johan Peeters, Chang Su, Babajide Keshinro, Carmen Delport, Elizabeth Sharkie, Jun Zhang, Chengyou Du, Kai Hu, André Strydom, I Bezem-Aviv, A Wachnicka, Pawan Kumar, Shangli Cheng, Kaijiang Kang,

BackgroundThis study assessed the safety and immunogenicity of the Ad26.ZEBOV and MVA-BN-Filo Ebola virus (EBOV) vaccine regimen in infants aged 4–11 months in Guinea and Sierra Leone.MethodsIn this phase 2, randomised, double-blind, active-controlled trial, we randomly assigned healthy infants (1:1 in a sentinel cohort, 5:2 for the remaining infants via an interactive web response system) to receive Ad26.ZEBOV followed by MVA-BN-Filo (Ebola vaccine group) or two doses of meningococcal quadrivalent ...

Elsevier BV