Mikhail Galakhov, Avelino Martı́n, Miguel Mena, Francisco Palácios, Carlos Yélamos, Paul R. Raithby,
... C]W(CO)5Mikhail Galakhov, Avelino Martin, Miguel Mena, Federico Palacios, Carlos Yelamos, and Paul R. RaithbyCite this: ...
Tópico(s): Ferrocene Chemistry and Applications
1995 - American Chemical Society | Organometallics
Gisselle Pérez-Machado, Ester Berenguer-Pascual, Miquel Bovea-Marco, Pedro Antonio Rubio-Belmar, Eva García-López, María José Garzón, Salvador Mena, Federico V. Pallardó, Teresa Bas, Juan R. Viña, José Luis García‐Gimenez,
Scoliosis is defined as the three-dimensional (3D) structural deformity of the spine with a radiological lateral Cobb angle (a measure of spinal curvature) of ≥10° that can be caused by congenital, developmental or degenerative problems. However, those cases whose etiology is still unknown, and affect healthy children and adolescents during growth, are the commonest form of spinal deformity, known as adolescent idiopathic scoliosis (AIS). In AIS management, early diagnosis and the accurate prediction ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2020 - Elsevier BV | Bone
Fernando Martínez, Elena Furió, María José Fabià, Albert Pérez, Verónica González-Albert, Gemma Rojo‐Martínez, Nicholas G. Martin, F.J. Mena-Martín, Federico Soriguer, Manuel Serrano‐Ríos, Felipe Javier Chaves, Juan Carlos Martı́n-Escudero, Josep Redón, M. Julia García‐Fuster,
Aims Retinal vein occlusion (RVO) is the most frequent retinal vascular disease after diabetic retinopathy in which arterial risk factors are much more relevant than venous factors. The objective was to evaluate the role of risk factors in the development of the first episode of RVO. Subjects and Methods One hundred patients with RVO [mean age 56 years, 42% females and mean body mass index (BMI) 27.5 kg/m2] were recruited consecutively from the outpatient clinic of a tertiary hospital in Valencia (Spain). ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2014 - Wiley | International Journal of Clinical Practice
Mena Ritota, Federico Marini, P. Sequi, Massimiliano Valentini,
HRMAS-NMR spectroscopy was used to assess the metabolic profile of sweet pepper (Capsicum Annum L.). One-dimensional and two-dimensional NMR spectra, performed directly on sample pieces of few milligrams, hence without any chemical and/or physical manipulation, allowed the assignment of several compounds. Organic acids, fatty acids, amino acids, and minor compounds such as trigonelline, C4-substituted pyridine, choline, and cinnamic derivatives were observed with a single experiment. A significant ...
Tópico(s): Meat and Animal Product Quality
2010 - American Chemical Society | Journal of Agricultural and Food Chemistry
Marta Sandoval Mena, Federico R. Waitoller,
La educación inclusiva es un movimiento global con diferentes prismas y ángulos locales. En los últimos años se ha definido la educación inclusiva desde la justicia social. Así, se viene vinculando la inclusión con la justa redistribución de la educación, el reconocimiento de todas las culturas, lenguajes y habilidades, y la representación política en la toma de decisiones educativas individuales y colectivas. Nuestro objetivo en este trabajo es sintetizar los puntos más importantes de ambas perspectivas ( ...
Tópico(s): Social Sciences and Policies
2022 - Q20013995 | Revista Española de Discapacidad
Alexandro Bonifáz, Amado Saúl, Cristina Mena, Adriana Valencia, V Paredes, L Fierro, Javier Santibáñez,
... for more papers by this authorC Mena, C Mena Dermatology Service, Hospital Infantil de México, Federico Gómez, México DF.Search for more papers by ... for more papers by this authorC Mena, C Mena Dermatology Service, Hospital Infantil de México, Federico Gómez, México DF.Search for more papers by ...
Tópico(s): Plant Pathogens and Fungal Diseases
2006 - Wiley | Journal of the European Academy of Dermatology and Venereology
Elisa Bonnin, María Rodrigo Riestra, Federico Marziali, Rafael Mena Osuna, Jordan Denizeau, Mathieu Maurin, Juan José Sáez, Mabel Jouve, Pierre‐Emmanuel Bonté, Wilfrid Richer, Fabien Névo, Sébastien Lemoine, Nicolas Girard, Marine Lefèvre, Édith Borcoman, Anne Vincent‐Salomon, Sylvain Baulande, Helene D. Moreau, Christine Sedlik, Claire Hivroz, Ana‐Maria Lennon‐Duménil, Jimena Tosello, Eliane Piaggio,
Abstract Regulatory T cells (Tregs) are plastic cells playing a pivotal role in the maintenance of immune homeostasis. Tregs actively adapt to the microenvironment where they reside; as a consequence, their molecular and functional profiles differ among tissues and pathologies. In tumors, the features acquired by Tregs remains poorly characterized. Here, we observe that human tumor-infiltrating Tregs selectively overexpress CD74, the MHC class II invariant chain. CD74 has been previously described ...
Tópico(s): Synthesis and Biological Evaluation
2024 - Nature Portfolio | Nature Communications
José Luis García‐Gimenez, Pedro Antonio Rubio-Belmar, Lorena Peiró-Chova, David Hervás, Daymé González-Rodríguez, José Santiago Ibáñez-Cabellos, Paloma Bas-Hermida, Salvador Mena, Eva García-López, Federico V. Pallardó, Teresa Bas,
The aetiology of adolescent idiopathic scoliosis (AIS) has been linked to many factors, such as asymmetric growth, neuromuscular condition, bone strength and genetic background. Recently, epigenetic factors have been proposed as contributors of AIS physiopathology, but information about the molecular mechanisms and pathways involved is scarce. Regarding epigenetic factors, microRNAs (miRNAs) are molecules that contribute to gene expression modulation by regulating important cellular pathways. We herein ...
Tópico(s): TGF-β signaling in diseases
2018 - Nature Portfolio | Scientific Reports
Sergio Luis‐Lima, Domingo Marrero-Miranda, Ana González‐Rinne, Armando Torres, José Manuel González‐Posada, Aurelio Rodríguez, Eduardo Salido, Ana Aldea‐Perona, Flavio Gaspari, Fabiola Carrara, J.A. Gómez-Gerique, Natalia Negrín‐Mena, Lourdes Pérez Tamajón, Federico González‐Rinne, Hugo Jiménez‐Hernández, Alejandro Jiménez, Esteban Porrini,
Formulas do not estimate renal function with acceptable precision and accuracy.We compared 51 creatinine-based and/or cystatin c-based formulas with a gold standard (iohexol plasma clearance) in 193 renal transplant recipients using concordance correlation coefficient, total deviation index, coverage probability and the error in chronic kidney disease (CKD) stage classification.No formula showed a concordance correlation coefficient greater than 0.90 (average for creatinine-based formulas: ∼0.70 and ...
Tópico(s): Dialysis and Renal Disease Management
2015 - Wolters Kluwer | Transplantation
The oxidative effect of nicotine was investigated using androgen biomarkers of redox status and wound healing in fibroblasts; using the antioxidant glutathione for confirmation of responses. Cultures of human gingival (HGF) and periosteal fibroblasts (HPF) were incubated with substrates 14C-testosterone/14C-4-androstenedione in the presence or absence of serial concentrations of nicotine (N100-500), glutathione (G1–5) and their combinations, in medium. At 24 h the medium was solvent extracted for metabolites, ...
Tópico(s): Fluorine in Organic Chemistry
2012 - Nature Portfolio | Scientific Reports
Lyudmila Bazhenova, Dong‐Wan Kim, Luigi Cavanna, Ji‐Youn Han, Jong Seok Lee, Hoon-Kyo Kim, Byoung Chul Cho, Marshall T. Schreeder, Ashiq Masood, Igor I. Rybkin, Melissa L. Johnson, Britt Boleman, Marta Batus, Estelamari Rodríguez, David S. Hong, Pasi A. Jänne, Raul Mena, Federico Cappuzzo, Ivor Percent, Vanessa Tassell, James G. Christensen, Demiana Faltaos, Richard C. Chao, Hirak Der‐Torossian, Diane Potvin, Ranee Mehra,
MGCD265 is a potent, orally available, small molecule RTK inhibitor of MET and Axl, both of which mediate signals for cell growth, survival, and migration. The Amethyst NSCLC trial is designed to evaluate the activity of MGCD265 in patients with NSCLC exhibiting genetic alterations involving MET. Alterations in MET, including gene amplification and/or genetic mutations, occur in approximately 7% of NSCLC cases converting MET to an oncogene capable of driving cancer development and progression. Amplification ...
Tópico(s): Liver physiology and pathology
2017 - Elsevier BV | Journal of Thoracic Oncology
Nancy Monroy‐Jaramillo, José David Abad Flores, Constanza García‐Delgado, América Villaseñor-Domínguez, Carlos Mena‐Cedillos, Mirna Toledo‐Bahena, Adriana Valencia, Adriana Sánchez-Boiso, Yumiko I. Akaki‐Carreño, Blanca del Río Navarro, Jesús Aguirre‐Hernández, Marisol López, Alicia Cervantes, Marco Cerbón, Verónica Fabiola Morán-Barroso,
... more papers by this authorC. Mena-Cedillos, C. Mena-Cedillos Department of Dermatology, Hospital Infantil de México Federico Gómez, Mexico City, MexicoSearch for more papers by ... more papers by this authorC. Mena-Cedillos, C. Mena-Cedillos Department of Dermatology, Hospital Infantil de México Federico Gómez, Mexico City, MexicoSearch for more papers by ...
Tópico(s): Pediatric health and respiratory diseases
2017 - Wiley | Journal of the European Academy of Dermatology and Venereology
Sheila Lorente-Pozo, Paula Navarrete, María José Garzón, Inmaculada Lara‐Cantón, Jesús Beltrán-García, Rebeca Osca-Verdegal, Salvador Mena, Eva García-López, Máximo Vento, Federico V. Pallardó, José Luis García‐Gimenez,
Background: Neonatal sepsis is a systemic condition widely affecting preterm infants and characterized by pro-inflammatory and anti-inflammatory responses. However, its pathophysiology is not yet fully understood. Epigenetics regulates the immune system, and its alteration leads to the impaired immune response underlying sepsis. DNA methylation may contribute to sepsis-induced immunosuppression which, if persistent, will cause long-term adverse effects in neonates. Objective: To analyze the methylome ...
Tópico(s): Immune responses and vaccinations
2021 - Frontiers Media | Frontiers in Immunology
Monia Savi, Leonardo Bocchi, Letizia Bresciani, Angela Falco, Federico Quaini, Pedro Mena, Furio Brighenti, Alan Crozier, Donatella Stilli, Daniele Del Rio,
One of the most recently proposed candidates as a potential trigger for cardiovascular diseases is trimethylamine-N-oxide (TMAO). Possible direct effects of TMAO on myocardial tissue, independent of vascular damage, have been only partially explored so far. In the present study, we assessed the detrimental direct effects of TMAO on cardiomyocyte contractility and intracellular calcium dynamics, and the ability of urolithin B-glucuronide (Uro B-gluc) in counteracting TMAO-induced cell damage. Cell ...
Tópico(s): Advanced Glycation End Products research
2018 - Multidisciplinary Digital Publishing Institute | Molecules
Robert M. Caudle, Laszlo Karai, N Mena, Brian Y. Cooper, Andrew J. Mannes, Federico M. Perez, Michael J. Iadarola, Zoltán Oláh,
Resiniferatoxin (RTX), a potent analog of capsaicin, was evaluated electrophysiologically in dorsal root ganglion (DRG) cells and cell lines ectopically expressing the vanilloid receptor type 1 (VR1) to determine if cell phenotype influenced RTXs neurotoxic properties. Furthermore, capsaicin and heat activation of VR1 were evaluated in these cells to determine if cellular damage was unique to RTX activation of the receptors. RTX application to DRG cells identified as type 1, 2 or 5, cell types known ...
Tópico(s): Ion channel regulation and function
2003 - Elsevier BV | NeuroToxicology
Mena N. Gadalla, Kundan Chaudhary, Christine M. Zgrabik, Federico Capasso, Evelyn L. Hu,
Titanium nitride (TiN) has been identified as a promising refractory material for high temperature plasmonic applications such as surface plasmon polaritons (SPPs) waveguides, lasers and light sources, and near field optics. Such SPPs are sensitive not only to the highly metallic nature of the TiN, but also to its low loss. We have formed highly metallic, low-loss TiN thin films on MgO substrates to create SPPs with resonances between 775-825 nm. Scanning near-field optical microscopy (SNOM) allowed ...
Tópico(s): Optical Coatings and Gratings
2020 - Optica Publishing Group | Optics Express
Ana Colado, José Luis Marín Franco, Esteban E. Elías, Mikele Amondarain, Maricef Vergara Rubio, Valeria Sarapura Martínez, Gregorio Cordini, Federico Fuentes, Luciana Balboa, Horacio Fernández Grecco, Miguel Arturo Pavlovsky, Fernando Bezares, Pablo Elías Morande, Mirta Giordano, Romina Gamberale, Mercedes Borge,
... to thank to María Tejeda, Romina Mariel Pagano, Federico Remes Lenicov and Agustina Mena for their technical assistance. Appendix S1. Supporting Information ...
Tópico(s): Lymphoma Diagnosis and Treatment
2020 - Wiley | American Journal of Hematology
Letizia Bresciani, Donato Angelino, Eugenio I. Vivas, Robert L. Kerby, Cristina García‐Viguera, Daniele Del Rio, Federico E. Rey, Pedro Mena,
Elderberries are good sources of anthocyanins, which are poorly absorbed in the upper gastrointestinal tract but extensively transformed into phenolic metabolites at the colonic level. Because different gut microbiota strains have different metabolism, the catabolism of anthocyanins may lead to interindividual differences in metabolite production. In this work, an anthocyanin-rich elderberry extract was incubated with three single gut microbial strains (Enterobacter cancerogenous, Bifidobacterium ...
Tópico(s): Fermentation and Sensory Analysis
2019 - American Chemical Society | Journal of Agricultural and Food Chemistry
Mena N. Gadalla, Andrew S. Greenspon, Michele Tamagnone, Federico Capasso, Evelyn L. Hu,
New opportunities for plasmonic applications at high temperatures have stimulated interest in refractory plasmonic materials that show greater stability at elevated temperatures than the more commonly used silver and gold (Au). Titanium nitride (TiN) has been identified as a promising refractory material, with deposition of TiN thin films through techniques ranging from plasma-enhanced atomic laser deposition to sputter deposition to pulsed laser deposition, on a variety of substrates, including MgO, ...
Tópico(s): GaN-based semiconductor devices and materials
2019 - American Chemical Society | ACS Applied Nano Materials
Mei Yee Koh, Vuvi Nguyen, Robert Lemos, Bryant G. Darnay, Galina M. Kiriakova, Mena Abdelmelek, Thai H. Ho, José A. Karam, Federico A. Monzon, Eric Jonasch, Garth Powis,
Abstract Clear-cell renal cell cancer (CRCC) is initiated typically by loss of the tumor-suppressor VHL, driving constitutive activation of hypoxia-inducible factor-1 (HIF1) and HIF2. However, whereas HIF1 has a tumor-suppressor role, HIF2 plays a distinct role in driving CRCC. In this study, we show that the HIF1α E3 ligase hypoxia-associated factor (HAF) complexes with HIF2α at DNA to promote HIF2-dependent transcription through a mechanism relying upon HAF SUMOylation. HAF SUMOylation was induced ...
Tópico(s): Renal cell carcinoma treatment
2014 - American Association for Cancer Research | Cancer Research
Svenja Sladek, Fiona McCartney, Mena Eskander, David J. Dunne, María José Santos-Martínez, Federico Benetti, Lidia Tajber, David J. Brayden,
The use of nanocarriers is being researched to achieve oral peptide delivery. Insulin-associated anionic polyelectrolyte nanoparticle complexes (PECs) were formed that comprised hyaluronic acid and chitosan in an optimum mass mixing ratio of 5:1 (MR 5), followed by coating with a pH-dependent polymer. Free insulin was separated from PECs by size exclusion chromatography and then measured by HPLC. The association efficiency of insulin in PECs was >95% and the loading was ~83 µg/mg particles. Dynamic ...
Tópico(s): Advancements in Transdermal Drug Delivery
2020 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Sergio Luis‐Lima, Flavio Gaspari, Natalia Negrín‐Mena, Fabiola Carrara, Laura Díaz‐Martín, Alejandro Jiménez, Federico González‐Rinne, Armando Torres, Esteban Porrini,
BackgroundRenal function can be estimated with formulas, which are inaccurate, or measured with gold standard methods, which are reliable but unpractical. We propose to simplify the plasma clearance of iohexol, a gold standard method to measure renal function, by dried blood spot (DBS) testing.
Tópico(s): Statistical Methods in Clinical Trials
2017 - Oxford University Press | Nephrology Dialysis Transplantation
Dora Buonfrate, M. A. Mena, Andrea Angheben, Ana Requena‐Méndez, José Muñóz, Federico Gobbi, Marco Albonico, Eduardo Gotuzzo, Zeno Bisoffi,
SUMMARY Strongyloides stercoralis is rarely recognized as a major public health issue, probably because its burden is largely underestimated. We reviewed the literature (both PubMed and ‘grey’ literature) about the prevalence of strongyloidiasis in Latin America, an area of presumable high endemicity. There were finally 88 papers involved in the analysis, covering the period between 1981 and 2011. Studies were heterogeneous in several aspects, such as the populations screened and the diagnostic methods ...
Tópico(s): Global Maternal and Child Health
2014 - Cambridge University Press | Epidemiology and Infection
José Luis García‐Gimenez, Fabián Sanchis‐Gomar, Giordano Lippi, Salvador Mena, David Ivars, Mari Carmen Gómez‐Cabrera, José Viña, Federico V. Pallardó,
Epigenetics comprises the study of chemical modifications in the DNA and histones that regulates the gene expression or cellular phenotype. However, during the last decade this term has evolved after the elucidation of different mechanisms (microRNAs and nuclear organization of the chromosomes) involved in regulating gene expression. Epigenetics and the new designed technologies capable to analyze epigenetic changes (e.g., methylated DNA, miRNAs expression, post-translational modifications on histones ...
Tópico(s): MicroRNA in disease regulation
2012 - Elsevier BV | Clinica Chimica Acta
Alfredo Palacios, Darío Balan, Osvaldo Ulises Garay, Magdalena Chocano Mena, Amanda Ribas Rietti Souto, Federico Augustovski, Andrés Pichón-Rivière,
La fragmentación del sistema de salud argentino en diferentes subsectores y niveles de cobertura se ve reflejada en la dificultad de acceso y la heterogeneidad de las fuentes de información disponibles de costos unitarios en salud. El objetivo de este estudio es presentar una versión actualizada de la Base de Costos Unitarios para los tres subsectores del sistema de salud de la Argentina (público, de seguridad social y privado) con la finalidad de apoyar y estimular la producción de evaluaciones ...
Tópico(s): Public Health in Brazil
2019 - Elsevier BV | Value in Health Regional Issues
Rafael Garcı́a Fuster, Elio Martín, Federico Paredes, Armando Mena, Sergio Cánovas, O. Gil, Fernando Hornero, Juan Martínez,
Neochordal repair is particularly limited in case of large prolapse with absence of a reference point on a nearby segment. Our aim was to overcome these limitations by means of a simple technique: the 'Folding Leaflet'.Ninety-six patients underwent this technique between January 2009 and August 2012 from a global mitral valve (MV) repair group of 384 patients. A subgroup of 68 patients with complex lesions, bileaflet, commissural or multisegment prolapse, was selected. These more challenging patients ...
Tópico(s): Aortic Disease and Treatment Approaches
2014 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Alejandro Cardona-Monzonís, José Luis García‐Gimenez, Salvador Mena, Helios Pareja‐Galeano, Fernando de la Guía-Galipienso, Giuseppe Lippi, Federico V. Pallardó, Fabián Sanchis‐Gomar,
Coronary artery disease (CAD) is the leading death cause worldwide. Non-coding RNA (ncRNA) are key regulators of genetic expression and thus can affect directly or indirectly the development and progression of different diseases. ncRNA can be classified in several types depending on the length or structure, as long non-coding RNA (lncRNA), microRNA (miRNA) and circularRNA (circRNA), among others. These types of RNA are present within cells or in circulation, and for this reason they have been used as ...
Tópico(s): MicroRNA in disease regulation
2020 - Springer Nature | Advances in experimental medicine and biology
Irene Costantini, Federico Donelli,
Tópico(s): International Development and Aid
2022 - Routledge | Small Wars and Insurgencies
Pedro Mena, A. Galindo, Jacinta Collado‐González, Sara Ondoño, Cristina García‐Viguera, Federico Ferreres, A. Torrecillas, Ángel Gil‐Izquierdo,
Abstract BACKGROUND No information exists on the consequences of water stress on the pomegranate ( Punica granatum L.) tree in terms of the quality and health/nutritional properties of its juice. In this study the influence of two different sustained deficit irrigation treatments on the colour, antioxidant activity and total phenolic compound, total anthocyanin, punicalagin and ellagic acid contents of pomegranate juice was assessed. RESULTS Control plants were irrigated at 75% ET o (crop reference ...
Tópico(s): Plant Physiology and Cultivation Studies
2012 - Wiley | Journal of the Science of Food and Agriculture
Paula Carmona, Federico Paredes, Eva Mateo, Armando V. Mena-Durán, Fernando Hornero, Juan Martínez-León,
We aim to describe our experience in coronary artery bypass grafting (CABG) with or without cardiopulmonary bypass by comparing intraoperative and postoperative outcomes. From January 1993 to June 2013, 3097 patients underwent consecutive emergency and scheduled CABG surgery. A total of 1770 patients underwent on-pump CABG (ONCABG) and 1327 off-pump CABG (OPCABG). A propensity score matching was performed to identify appropriate matched-pair patients; univariable and multivariable logistic regression ...
Tópico(s): Cardiac Valve Diseases and Treatments
2016 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery