David P. Witte, Peter J. Stambrook, Estrella Feliciano, C. Jones, M. A. Lieberman,
Abstract A recently described human megakaryocytic tumor cell line was analyzed for the presence of growth factor activity and was found to produce large quantities of transforming growth factor b̃‐like (TGF‐b̃) and basic fibroblast growth factor‐like (bFGF) activities. Growth factor activities were identified using a radioreceptor assay for the TGF‐b̃‐like activity, a heparin‐binding assay for the b‐FGF‐like activity, and a demonstration of distinct biological activities for each type of factor. ...
Tópico(s): Proteoglycans and glycosaminoglycans research
1988 - Wiley | Journal of Cellular Physiology
Desarom Teso, Jill Sommerset, Matthew Dally, Beejay Feliciano, Yolanda Vea, Riyad Karmy Jones,
In the setting of Peripheral Arterial Disease (PAD), pedal arch interrogation by ultrasound has not been well described. Patients with noncompressible vessels and/or open wounds of the foot may preclude the use of ankle-brachial indices, toe pressure measurements, or TcPO2, respectively. We propose that pedal artery interrogations with Pedal Acceleration Time (PAT) can be a predictor for limb salvage in patients with Chronic Limb-Threatening Ischemia (CLTI).A retrospective review of a prospectively ...
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2021 - Elsevier BV | Annals of Vascular Surgery
Walter L. Biffl, Ernest E. Moore, David V. Feliciano, Roxie M. Albrecht, Martin A. Croce, Riyad Karmy-Jones, Nicholas Namias, Susan Rowell, Martin A. Schreiber, David V. Shatz, Karen J. Brasel,
Biffl, Walter L. MD; Moore, Ernest E. MD; Feliciano, David V. MD; Albrecht, Roxie M. MD; Croce, Martin A. MD; Karmy-Jones, Riyad MD; Namias, Nicholas MD; Rowell, Susan E. ...
Tópico(s): Hernia repair and management
2018 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Peter A Maningas, Kenneth L. Mattox, Paul E. Pepe, Robert L. Jones, David V. Feliciano, Jon M. Burch,
We report the results of the first clinical study on the use of a hypertonic saline-dextran solution for the prehospital management of hypotensive victims of penetrating trauma. During a 4-month period, 48 trauma patients with penetrating injuries and a prehospital systolic blood pressure of 90 mm Hg or less were infused in-field with 250 ml of either a hypertonic saline-dextran solution or the crystalloid plasmalyte A. There were no complications associated with the infusion of the hypertonic saline- ...
Tópico(s): Cardiac Arrest and Resuscitation
1989 - Elsevier BV | The American Journal of Surgery
Jakub Kawalec, Carmelita Reyes, V.K. Penfield, Vincent J. Hetherington, D. Hays, F. Feliciano, D. Gartz, John G. Jones, Rosario Esposito, M.S. Cernica,
The Ceralas D15 diode laser is a GaAlAs diode laser that delivers up to 15 watts of optical power at 980 nm using a quartz fiber delivery system. The purpose of this study was to evaluate the Ceralas D15 laser as an adjunct tool in wound care. Ulcers were treated with the laser once every two weeks for a minimum of four treatments. During this time, the patients continued their previously prescribed treatment. The change in area of the ulcers and the change in bacterial count were evaluated following ...
Tópico(s): Dermatologic Treatments and Research
2001 - Elsevier BV | The Foot
Walter L. Biffl, Ernest E. Moore, David V. Feliciano, Roxie A. Albrecht, Martin A. Croce, Riyad Karmy-Jones, Nicholas Namias, Susan Rowell, Martin A. Schreiber, David V. Shatz, Karen J. Brasel,
This is a recommended management algorithm from the Western Trauma Association addressing the diagnostic evaluation and management of esophageal injuries in adult patients. Because there is a paucity of published prospective randomized clinical trials that have generated Class I data, the recommendations herein are based primarily on published observational studies and expert opinion of Western Trauma Association members. The algorithms and accompanying comments represent a safe and sensible approach ...
Tópico(s): Trauma Management and Diagnosis
2015 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Sungho Lim, Pegge Halandras, Richard Hershberger, Bernadette Aulivola, Paul R. Crisostomo,
... than previously realized.1Crisostomo P.R. Cho J. Feliciano B. Klein J. Jones D. Dalsing M.C. Period frequency of iliofemoral ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2016 - Elsevier BV | Journal of Vascular Surgery Cases and Innovative Techniques
Jill Sommerset, Desarom Teso, Riyad Karmy-Jones, Yolanda Vea, Beejay Feliciano,
Ankle-brachial index (ABI) and duplex ultrasound (DUS) are accepted standardized tests performed on patients with suspected peripheral arterial disease. In the nondiabetic patient, ABIs can be a reliable test for disease above the level of the ankle. Toe brachial index (TBI) is also an accepted modality to test for small vessel disease. However, ABIs and TBIs fall short in providing a complete evaluation of arterial flow especially in pedal arteries in the setting of noncompressible arteries. Direct ...
Tópico(s): Diagnosis and Treatment of Venous Diseases
2020 - SAGE Publishing | Journal for Vascular Ultrasound
Jill Sommerset, Riyad Karmy-Jones, Matthew Dally, Beejay Feliciano, Yolanda Vea, Desarom Teso,
Arterial duplex ultrasound (DUS) and ankle-brachial indices (ABIs) are accepted methods for assessing lower limb arterial perfusion. However, in a significant number of diabetic patients, medial wall calcification often precludes an ABI measurement. Direct, noninvasive duplex imaging of the pedal arch in the setting of peripheral arterial disease (PAD) has not been well evaluated. Although plantar arch interrogation is new to vascular ultrasound, imaging the plantar arteries appears to be a reliable ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2019 - Elsevier BV | Annals of Vascular Surgery
Paul R. Crisostomo, Jenny Cho, Beejay Feliciano, Janet D. Klein, Debra Jones, Michael C. Dalsing,
BackgroundPatients with iliofemoral deep venous thrombosis (DVT) are at highest risk for the postthrombotic morbidity including all aspects of the postthrombotic syndrome. Invasive therapies such as catheter-directed thrombolysis (CDT) and/or mechanical thrombectomy with or without angioplasty and stenting and in some cases open operative thrombectomy improves venous patency, venous valve function, and quality of life in patients with acute iliofemoral DVT. What is the current frequency of acute iliofemoral ...
Tópico(s): Central Venous Catheters and Hemodialysis
2010 - Elsevier BV | Journal of Vascular Surgery
Errol D. Jones, Matt S. Meier, Feliciano Rivera,
... Mexican American History. By Meier Matt S. Rivera Feliciano. (Westport, Connecticut: Greenwood Press, 1981. x + 498 pp. Maps, charts, tables, appendixes, bibliography, index. $35.00.) Errol D. Jones Errol D. Jones Boise State University Search for ...
Tópico(s): Latin American and Latino Studies
1983 - Oxford University Press | Western Historical Quarterly
Jill Sommerset, Desarom Teso, Beejay Feliciano, Yolanda Vea, Michelle Sentman, Natalie Zimmerman, Calli Nyholm, Rachel Honl, Riyad Karmy-Jones,
Evaluation of the pedal arteries has not been well evaluated by noninvasive duplex ultrasound. It offers an alternative approach that directly studies the angiosome supply of the foot. The goal of this article is to describe the technique, protocol, and criteria to properly evaluate the pedal arteries of the foot with noninvasive duplex ultrasound.
Tópico(s): Diagnosis and Treatment of Venous Diseases
2019 - SAGE Publishing | Journal for Vascular Ultrasound
Kristopher Ray S. Pamintuan, Maria Aira L. Calma, Kristine Anne D. Feliciano, Keith Jones Paul D. Lariba,
Abstract Although renewable sources of energy including geothermal, hydropower, wind, solar and biomass are utilized by the Philippines, coal-fired power plants remain the main source of electrical energy consumed by Filipino households. To lessen the nation’s dependence on fossil fuels, new and innovative sources of renewable energy should be explored. Plant-Microbial Fuel Cells (PMFCs) are a promising renewable energy technology that can be used to supplement our demand for electricity. PMFCs utilize ...
Tópico(s): Electrocatalysts for Energy Conversion
2020 - IOP Publishing | IOP Conference Series Earth and Environmental Science
Produção Nacional
Silas Mendes Feliciano, Jones Alves de Souza, Maria de Nazaré Paiva da Silva, Rosilene Nascimento Teles,
Este artigo aborda a utilização de uma atividade gamificada, como uma opção para o processo de aprendizagem e avaliação, e tem como objetivo explorar a implementação da gamificação no ensino de Biologia, inspirado por experiências durante a fase de regência de estágio supervisionado. O estudo foi aplicado em uma Escola Estadual de Tempo Integral localizada no municipio de Lábrea, interior do Amazonas. O método foi bem aceito pelos alunos que se engajaram e mostraram maior interesse no conteúdo exposto, ...
Tópico(s): Education and Digital Technologies
2023 - Arche Scientific and Editorial Consultancy | Revista Ibero-Americana de Humanidades, Ciências e Educação
John A. Kern, Curtis G. Tribble, William D. Spotnitz, Bryan Rodgers, Thomas M. Daniel,
... 1990; 25: 35-43 PubMed Google Scholar , 4 Feliciano DV Cruse PA Mattox KL Bitondo CG Burch JM Noon GP et al. Delayed diagnosis of injuries to the diaphragm after penetrating wounds. J Trauma. 1988; 28: 1135-1144 Crossref PubMed Scopus (118) Google Scholar , 5 Jones JC Nyreen MR Stowell V Traumatic diaphragmatic hernia ...
Tópico(s): Pleural and Pulmonary Diseases
1993 - Elsevier BV | CHEST Journal
Jean-Eudes Trihan, Jeanne Hersant, Simon Lecoq, Samir Henni, Cédric Fontaine, Romain Prigent, Guillaume Mahé, Damien Lanéelle,
... Google Scholar, 6Teso D. Sommerset J. Dally M. Feliciano B. Vea Y. Jones R.K. Pedal acceleration time (PAT): a novel ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2024 - Elsevier BV | Journal of Vascular Surgery
Walter L. Biffl, Ernest E. Moore, Martin A. Croce, James W. Davis, Raúl Coimbra, Riyad Karmy-Jones, Robert C. McIntyre, Frederick A. Moore, Jason L. Sperry, Ajai K. Malhotra, David V. Feliciano,
This is a recommended management algorithm from the Western Trauma Association addressing the diagnostic evaluation and management of pancreatic injuries in adult patients. Because there is a paucity of published prospective randomized clinical trials that have generated Class I data, the recommendations herein are based primarily on published observational studies and expert opinion of Western Trauma Association members. The algorithm (Fig. 1) and accompanying comments represent a safe and sensible ...
Tópico(s): Hernia repair and management
2013 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Hila Shaim, Mayra Shanley, Rafet Başar, May Daher, Joy Gumin, Daniel B. Zamler, Nadima Uprety, Fang Wang, Yuefan Huang, Konrad Gabrusiewicz, Qi Miao, Jinzhuang Dou, Abdullah Alsuliman, Lucila Nassif Kerbauy, Sunil Acharya, Vakul Mohanty, Mayela Carolina Mendt, Sufang Li, JunJun Lu, Jun Wei, Natalie W. Fowlkes, Elif Gokdemir, Emily L. Ensley, Mecit Kaplan, Cynthia Kassab, Li Li, Gonca Ozcan, Pinaki P. Banerjee, Yifei Shen, April Gilbert, Corry M. Jones, Mustafa Bdiwi, Ana Karen Nunez Cortes, Enli Liu, Jun Yu, Nobuhiko Imahashi, Luis Muniz-Feliciano, Ye Li, Jian Hu, Giulio Draetta, David Marín, Dihua Yu, Stephan Mielke, Matthias Eyrich, Richard E. Champlin, Ken Chen, Frederick F. Lang, Elizabeth J. Shpall, Amy B. Heimberger, Katayoun Rezvani,
Glioblastoma multiforme (GBM), the most aggressive brain cancer, recurs because glioblastoma stem cells (GSCs) are resistant to all standard therapies. We showed that GSCs, but not normal astrocytes, are sensitive to lysis by healthy allogeneic natural killer (NK) cells in vitro. Mass cytometry and single-cell RNA sequencing of primary tumor samples revealed that GBM tumor-infiltrating NK cells acquired an altered phenotype associated with impaired lytic function relative to matched peripheral blood ...
Tópico(s): Phagocytosis and Immune Regulation
2021 - American Society for Clinical Investigation | Journal of Clinical Investigation
Produção Nacional
Maria de Nazaré Paiva da Silva, Silas Mendes Feliciano, Jones Alves de Souza, Jusiany Pereira da Cunha dos Santos,
Este artigo buscou descrever a experiência adquirida durante a fase de estágio em uma escola Estadual do interior do Amazonas, atividade que explorou a aplicação de um jogo que aconteceu na turma do 1º ano do ensino médio abordando o tema bingo dos conjuntos numéricos. A abordagem adotada neste trabalho proporcionou uma maneira inovadora de estimular os alunos a buscar conhecimento, tornando-os mais participativos em sala de aula por meio de competições e desafios. A atividade foi dividida em dois ...
Tópico(s): Education and Digital Technologies
2023 - Arche Scientific and Editorial Consultancy | Revista Ibero-Americana de Humanidades, Ciências e Educação
John U. Zink, Bryan C. Morse, Gary Vercruysse, Christopher J. Dente, Yonge Jones, David V. Feliciano,
Tópico(s): Otolaryngology and Infectious Diseases
2013 - SAGE Publishing | The American Surgeon
Peter A Maningas, Kenneth L. Mattox, Paul E. Pepe, Rachel Jones, David V. Feliciano, Jon M. Burch,
... P. A.; MATTOX, K. L.; PEPE, P. E.; JONES, R. L.; FELICIANO, D. V.; BURCH, J. M. Author Information
Tópico(s): Trauma and Emergency Care Studies
1989 - Lippincott Williams & Wilkins | Survey of Anesthesiology
Nick D. Jones, Megan Missanelli, Leon Dure, Ellen Funkhouser, Jaimee Kaffka, Meredith L. Kilgore, Kenneth G. Saag, Feliciano Yu, Monika M. Safford,
Children with epilepsy are at risk of having their anticonvulsant regimens disrupted during the home-to-hospital transition. We sought to estimate the frequency of anticonvulsant medication errors during transition into the hospital in children with epilepsy hospitalized for reasons other than seizures, and to examine factors associated with the occurrence of such errors. We examined the medical records to identify errors related to anticonvulsant administration during the transition into the hospital ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2012 - SAGE Publishing | Journal of Child Neurology
DIANE D HESTER, TARA M COGHLIN, NANCY L HSIEH,
... Scholar, (6)Moore F.A Moore E.E Jones T.N McCroskey B.L Peterson V.M TEN versus TPN following major abdominal trauma-reduced septic morbidity.J Trauma. 1989; 29: 916-922Google Scholar, (7)Moore F.A Feliciano D.V Andrassy R.J McArdle A.H ... Scholar, (6)Moore F.A Moore E.E Jones T.N McCroskey B.L Peterson V.M TEN versus TPN following major abdominal trauma-reduced septic morbidity.J Trauma. 1989; 29: 916-922Google Scholar, (7)Moore F.A Feliciano D.V Andrassy R.J McArdle A.H ... Scholar, (6)Moore F.A Moore E.E Jones T.N McCroskey B.L Peterson V.M TEN versus TPN following major abdominal trauma-reduced septic morbidity.J Trauma. 1989; 29: 916-922Google Scholar, (7)Moore F.A Feliciano D.V Andrassy R.J McArdle A.H ...
Tópico(s): Abdominal Surgery and Complications
1996 - Elsevier BV | Journal of the American Dietetic Association
Alex John London, Christopher W. Seymour,
... Wiley; Nirav Shah; Tovah Klein; Julie Castex; Phillip Feliciano; Jacqueline Olivo; Marian Ghaly; Zainub Javed; Alexandra Nawrocki; Anthony Vecchiarelli; Nikki Vigil; Vijaya Cherukuri; Erica Burden; Dawn Linn; Laura Fisher; Vijay Patel; Praksha Patel; Yuti Patel; Leonard Ellison; Jeffrey Harrison; Binod Shah; Sugata Shah; Upinder Singh; Julia Donahue; Yasmin Jazayeri; Anita Gupta ; N Chandrasekar; Beth Moritz; Tabitha Fortt; Anisa Fortt; Ingrid Jones-Ince; Alix McKee; Christy Schattinger; Jason Wilson; Brenda ...
Tópico(s): Vaccine Coverage and Hesitancy
2023 - American Medical Association | JAMA
Maxwell D. Gruber, Jill Sommerset, Cali Hansen-Nyholm, Beejay Feliciano, Yolanda Vea, Riyad Karmy-Jones,
Steal phenomenon after upper extremity hemodialysis access is a clinical diagnosis and consists of signs and symptoms ranging from pain during dialysis to tissue loss. Duplex ultrasonography of the access site and limb arterial perfusion often serves as an adjunct to the diagnosis but can have limitations and there is no specific duplex measurement that indicates that an intervention will be a success. We have used hand acceleration time (HAT) to assess perfusion in a number of trauma and shock cases ...
Tópico(s): Hemodynamic Monitoring and Therapy
2023 - SAGE Publishing | Journal for Vascular Ultrasound
Pete Smith, Fabrizio Albanito, M.J. Bell, Jessica Bellarby, Sergey Blagodatskiy, Arindam Datta, Marta Dondini, Nuala Fitton, Helen Flynn, Astley Hastings, Jon Hillier, Edward O. Jones, Matthias Kuhnert, Dali Nayak, Mark Pogson, Mark Richards, Gosia Sozanska-Stanton, Shifeng Wang, Jagadeesh Yeluripati, Emily Bottoms, Christopher Brown, Jenny Farmer, Diana Feliciano, Hao Cui, Andy D. Robertson, Sylvia H. Vetter, Hon Man Wong, Jo Smith,
Systems approaches have great potential for application in predictive ecology. In this paper, we present a range of examples, where systems approaches are being developed and applied at a range of scales in the field of global change and biogeochemical cycling. Systems approaches range from Bayesian calibration techniques at plot scale, through data assimilation methods at regional to continental scales, to multi-disciplinary numerical model applications at country to global scales. We provide examples ...
Tópico(s): Climate variability and models
2011 - Royal Society | Philosophical Transactions of the Royal Society B Biological Sciences
Robert J. Shulman, Sarah Phillips,
... of Science®Google Scholar 48Moore FA, Moore EE, Jones TN, McCroskey BL, Peterson VM. TEN versus TPN following major abdominal trauma-reduced septic morbidity. J Trauma 1989; 29: 916–22. 10.1097/00005373-198907000-00003 CASPubMedWeb of Science®Google Scholar 49Moore FA, Feliciano DV, Andrassy RJ, McArdle AH, Booth FV, Morgenstein- ...
Tópico(s): Childhood Cancer Survivors' Quality of Life
2003 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition
Jill Sommerset, Beejay Feliciano, Riyad Karmy-Jones, Yolanda Vea, Matthew Dally, Desarom Teso,
We have established that pedal acceleration time (PAT) in nondiabetic limbs are highly correlative with ankle-brachial indices. We propose that PAT can be utilized in diabetic patients with noncompressible vessels and is an excellent predictor of wound healing. We performed a retrospective analysis in a prospective data base of diabetic patients with chronic limb-threatening ischemia (CLTI). We focused on patients with diabetes and isolated infrapopliteal arterial occlusive disease. Fifty-four limbs ...
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2020 - Elsevier BV | Journal of Vascular Surgery
Gregory Joseph, John Barnes, Eduardo Azziz‐Baumgartner, Melissa Arvay, Alicia M. Fry, Aron J. Hall, Preeta K. Kutty, Adam MacNeil, L. Clifford Donald, Sue Reynolds, Stephan Schrag, Nong Shang, Robert S. Slaughter, Natalie J. Thornburg, Jennife Verani, Rose Wang, Danielle Rentz Hunt, Brian Sokol, Robin Bloodworth, Claire Douglas, I. E. Gerber, Louise Hadden, Jenna A. Harder, Nancy McGarry, Steve Pickett, Brandon Poe, Meghan Shea, John G. Thacker, Pearl Q. Zheng, Peenaz Mistry, Kelly Patlan, Jessica Flores, Jazmin Duque, Laura Edwards, Jini Etolue, Lindsay LeClair, Khaila Prather, Michael Smith, Kempapura Murthy, Nicole Calhoun, Eric Hoffman, Martha Zayed, Joel Blais, Jason Ettlinger, Natalie Settele, Rupande Patel, Elisa L. Priest, Jennifer D. Thomas, Muralidhar Jatla, Madhava Beeram, Alejandro C. Arroliga, Yolanda Prado, Daniel S. Sapp, Mi Lee, Matt Hornbrook, Kristin Bialobok, Jennifer Alaspa, Daniel Stafki, Mary Ann Robinson, Jill Dolezilek, Leia Hoffman, Tyna Connor, Catherine Luzio, Stuart Kendrick, Hannah Cowling, Olivia Healy, Gavin Tovar, Meccah Jarrah, Assumpta Nsengiyunva, Alison Slocum, Lili Steffen, Saskia Smidt, Alissa Coleman, Carly Deal, Hanna Hanson, Italia Trejo, Jeremy Makar, Sofia Grijalva, Krystal S. Jovel, Priyanka Sharma, Xiaoxiao Sun, Janko Nikolich‐Žugich, Joe K. Gerald, J. W. Fisher, Karl Krupp, Lynn B. Gerald, Sally R. Littau, Ferris A. Ramadan, Erin Woods, Flavia Nakayima Miiro, Gayatri Arani, Nicholas Tang, Nora Baccam, Ashley A. Lowe, Amelia Lobos, A. Yingst, Danielle Stea, Natalya Mayhew, R. Nava, Cynthia Porter, Andrea Carmona, Ariyah strong, Ashlyn Flangos, Caroline Klinck, Celia Pikowski, Chloe Hendrix, Cielo Perez, Cierra Morris, Erika Goebert, Gianna Taylor, J. W. SR. SOWELL, Jen Scott, Joe Mirabito, Jordan J. Baker, Kaitlyn Naff, Karysa Carson, Kennedy Obrien, Kiara Earley, Kristisha Mevises, Mayra P. Martinez, M.P. Peña, Raven Hilyard, Rezwana Islam, Riley Perlman, Sarah Murray, Shelby Capell, S. Bigler, Ta’Nya Thomas, Tatum Butcher, Taylor Graham, Christian Rojas, J. H. Jones, Brandon Astor, Ian Lee, Meghal S. Desai, Victoria Gómez, Rachael Reyes, Damena Gallimore‐Wilson, Roger Noriega, Annabel Reyes, Brigitte Madan, Alexandra Cruz, Olga Carrera, Nathaly Suarez, Paola Louzado Feliciano, Johanna Garibaldi, Aimee Green, Addison Testoff, Rachel T. Brown, Camie Schaefer, Arlyne Arteaga, Matthew Bruner, Daniel Dawson, Emilee Eden, Jenna Praggastis, Joseph B. Stanford, Jeanma Mayer, Marcus Stucki, Riley Campbell, Kathy Tran, Madele Smith, Braydon Black, Christina Pick, Madison Tallman, Chapman Cox, Derrick Wong, Michael A. Langston, Adriel Fugal, Fiona Tsang, Maya Wheeler, Gretchen Maughan, Megan Wilson, Pasha Stinson, Jesse Feiring Williams, Taryn Smith, Seon Reed, Jinyi Mao, Nikki allacher, Kendal Chatard, Jenna Vo, Katie Luong, Ryder Jordin, Grace Stewart, Brock Bourdelle, Timina Powaukee, Max Minoughan, Hannah Whiting, Anika Souza, Ian Arlington, Lauren Anderson, Trevor Stubbs, Katherine Park, Talesha Jones, Mark G. Thompson, Sarang K. Yoon, Allison L. Naleway, Jennifer K. Meece, Thomas Fabrizio, Alberto J. Cabán-Martinez, Jefferey L. Burgess, Manjusha Gaglani, Lauren E.W. Olsho, Allen C. Bateman, Jessica Lundgren, L. S. Grant, Andrew L. Phillips, Holly C. Groom, Elisha Stefanski, Natasha Schaefer Solle, Katherine Ellingson, Karen Lutrick, Kayan Dunnigan, Meredith G. Wesley, Kyley Guenther, Angela Hunt, Josephine Mak, Kurt T. Hegmann, Jennifer L. Kuntz, Adam Bissonnette, James Hollister, Spencer Rose, Tyler Morrill, Karley Respet, Ashley Fowlkes, Matthew S. Thiese, Patrick Rivers, Meghan K. Herring, Marilyn J. Odean, Young M. Yoo, Matthew Brunner, Edward J. Bedrick, Deanna E. Fleary, John T. Jones, Jenna Praggastis, James K. Romine, Monica Dickerson, Sana Khan, Julie Mayo Lamberte, Shawn C. Beitel, Richard J. Webby, Harmony L. Tyner,
Importance Data on the epidemiology of mild to moderately severe COVID-19 are needed to inform public health guidance. Objective To evaluate associations between 2 or 3 doses of mRNA COVID-19 vaccine and attenuation of symptoms and viral RNA load across SARS-CoV-2 viral lineages. Design, Setting, and Participants A prospective cohort study of essential and frontline workers in Arizona, Florida, Minnesota, Oregon, Texas, and Utah with COVID-19 infection confirmed by reverse transcriptase–polymerase ...
Tópico(s): SARS-CoV-2 detection and testing
2022 - American Medical Association | JAMA
Mayra Shanley, May Daher, Jinzhuang Dou, Sufang Li, Rafet Başar, Hind Rafei, Merve Dede, Joy Gumin, Jezreel Pantaleόn Garcίa, Ana Karen Nunez Cortes, Shan He, Corry M. Jones, Sunil Acharya, Natalie W. Fowlkes, Donghai Xiong, Sanjay K. Singh, Hila Shaim, S. Hicks, Bin Liu, Abhinav K. Jain, Mohammad F. Zaman, Qi Miao, Ye Li, Nadima Uprety, Enli Liu, Luis Muniz-Feliciano, Gary Deyter, Vakul Mohanty, Patrick Zhang, Scott E. Evans, Elizabeth J. Shpall, Frederick F. Lang, Ken Chen, Katayoun Rezvani,
Glioblastoma (GBM) is an aggressive brain cancer with limited therapeutic options. Natural killer (NK) cells are innate immune cells with strong anti-tumor activity and may offer a promising treatment strategy for GBM. We compared the anti-GBM activity of NK cells engineered to express interleukin (IL)-15 or IL-21. Using multiple in vivo models, IL-21 NK cells were superior to IL-15 NK cells both in terms of safety and long-term anti-tumor activity, with locoregionally administered IL-15 NK cells proving ...
Tópico(s): T-cell and B-cell Immunology
2024 - Cell Press | Cancer Cell