Produção Nacional
Revisado por pares
Júlio Carlos Afonso, Leandro Anido Noronha, Renata Pinheiro Felipe, Nicolas Freidinger,
This work shows some laboratory waste management developed in order to recover some elements or to prepare the waste for a correct final disposal.The 25 elements chosen cover basically all chemical behaviors found for the metals in the Periodic Table .The treatments adopted were based on the classical behavior in aqueous solution (wet chemistry) but an important condition for a full success was the previous knowledge of the qualitative composition of the wastes treated.Some general trends were found: ...
Tópico(s): Chemistry and Chemical Engineering
2003 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Daniela Felipe Pinheiro, Patrícia Fernanda Felipe Pinheiro, J. Buratini, A. C. S. Castilho, P. F. Lima, Luzia A. Trinca, Maria de Lourdes Mendes Vicentini-Paulino,
Intrauterine dietary restriction may cause changes in the functioning of offspring organs and systems later in life, an effect known as fetal programming. The present study evaluated mRNA abundance and immunolocalization of nutrient transporters as well as enterocytes proliferation in the proximal, median and distal segments of small intestine of rats born to protein-restricted dams. Pregnant rats were fed hypoproteic (6% protein) or control (17% protein) diets, and offspring rats were evaluated at ...
Tópico(s): Digestive system and related health
2013 - Portland Press | Clinical Science
Produção Nacional
Revisado por pares
Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, Margareth Afonso Torres,
Type 1 diabetes mellitus (T1DM) is a chronic disease characterized by autoimmune destruction of pancreatic beta cells and inadequate insulin production. Remission criteria in T1DM take into account serum levels of C-peptide and glycosylated hemoglobin, as well as the dose of insulin administered to the patient. However, remission of T1DM lasting longer than 1 year is rare. We describe here the cases of two young women who presented with positive glutamic acid decarboxylase (GAD) antibody and classic ...
Tópico(s): Diabetes Management and Research
2016 - Wiley | Endocrinology Diabetes and Metabolism Case Reports
Produção Nacional
Revisado por pares
Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, Maria Luisa Trabachin,
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease characterized by destruction of pancreatic beta cells through cell injury caused primarily by cytotoxic T lymphocytes (CD8+). The pathophysiological basis of T1DM seems to be an imbalance between a reduced function of T regulatory lymphocytes and an increased inflammatory activity of Th17 lymphocytes caused by increased production of inflammatory cytokines, as IL-1β, IL-6, IL-17 and IFN-gamma due to environmental factors and genetic predisposition. ...
Tópico(s): Neuroendocrine Tumor Research Advances
2018 - Elsevier BV | International Immunopharmacology
Produção Nacional
Revisado por pares
Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, Susana Nogueira Diniz, Andrea Fabbri, Marco Infante,
Type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA) represent the most common types of autoimmune diabetes and are characterized by different age of onset, degrees of immune-mediated destruction of pancreatic beta cells and rates of disease progression towards insulin dependence. Several immunotherapies aimed to counteract autoimmune responses against beta cells and preserve beta-cell function are currently being investigated, particularly in T1D. Preliminary findings suggest a potential ...
Tópico(s): Diabetes Treatment and Management
2021 - Elsevier BV | International Immunopharmacology
Produção Nacional
Revisado por pares
Victor Rafael Matos Coimbra, Felipe Grillo Pinheiro, Felipe Wartchow, Tatiana Baptista Gibertoni,
Tópico(s): Botanical Research and Applications
2015 - Springer Science+Business Media | Mycological Progress
... Gleyson Borges Castro, Aline Christine Bernegossi, Mayara Caroline Felipe, Fernanda Rodrigues Pinheiro, Vanessa Colombo-Corbi, Douglas Aparecido Girolli, Guilherme Rossi ... ctdb.2021.12.020Gleyson B. Castro, Fernanda R. Pinheiro, Mayara C. Felipe, Aline C. Bernegossi, Douglas Girolli, Guilherme R. Gorni, ... 0Gleyson B. Castro, Aline C. Bernegossi, Fernanda R. Pinheiro, Mayara C. Felipe, Juliano J. Corbi Effects of Polyethylene Microplastics on ...
Tópico(s): Invertebrate Taxonomy and Ecology
1937 - University of Chicago Press | Physiological Zoology
... Aline Janke, Clarisse Palma-Silva, Eliane Kaltchuk-Santos, Felipe G. Pinheiro, Gecele M. Paggi, Luis E.S. Soares, Márcia ...
Tópico(s): Growth and nutrition in plants
1904 - University of Chicago Press | Botanical Gazette
Produção Nacional
Revisado por pares
Carla Q. Feitoza, Giselle Martins Gonçalves, Patrícia Semedo, Marcos Antônio Cenedeze, Hélady Sanders-Pinheiro, Felipe Caetano Beraldo, Oscar Fernando, Pavão dos Santos, Vicente de Paula Antunes Teixeira, Marlene Antônia dos Reis, Marilda Mazzali, Álvaro Pacheco‐Silva, Niels Olsen Saraiva Câmara,
Ischemia and reperfusion injury (IRI) contributes to the development of chronic interstitial fibrosis/tubular atrophy in renal allograft patients. Cyclooxygenase (COX) 1 and 2 actively participate in acute ischemic injury by activating endothelial cells and inducing oxidative stress. Furthermore, blockade of COX 1 and 2 has been associated with organ improvement after ischemic damage. The aim of this study was to evaluate the role of COX 1 and 2 in the development of fibrosis by performing a COX 1 ...
Tópico(s): Cerebrovascular and genetic disorders
2008 - BioMed Central | Molecular Medicine
Produção Nacional
Revisado por pares
Fernando Korn Malerbi, Paulo Henrique Morales, Michel Eid Farah, Karla Rezende Guerra Drummond, Tessa Cerqueira Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Ricardo Vessoni Perez, Franz Schubert Lopes Leal, Marília Brito Gomes, Sérgio Atala Dib,
Diabetic retinopathy is the main cause of preventable blindness in the economically active population in western countries. Diabetic retinopathy screening is effective in preventing blindness and can be performed through various diagnostic methods. Our objective is to compare binocular indirect ophthalmoscopy (BIO) to telemedicine protocols of digital retinography for diabetic retinopathy screening in a large and heterogenous type 1 diabetes population in a developing country. Data from 1266 Type ...
Tópico(s): Glaucoma and retinal disorders
2015 - BioMed Central | Diabetology & Metabolic Syndrome
Produção Nacional
Revisado por pares
Edson C. Paz, Luci R. Aveiro, Victor S. Pinheiro, Felipe M. Souza, Verônica Bocalon Lima, Luiz Fernando da Silva, Peter Hammer, Marcos R.V. Lanza, Mauro C. Santos,
In this paper, we report on the development of a new catalyst for H2O2 electrogeneration for the preparation of a gas diffusion electrode (GDE) for water treatment by electrochemical advanced oxidation processes (EAOPs). Catalysts based on tungsten oxide nanoparticles on Vulcan XC72 and Printex 6L carbons were studied by X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS), contact angle measurements and oxygen reduction ...
Tópico(s): TiO2 Photocatalysis and Solar Cells
2018 - Elsevier BV | Applied Catalysis B Environment and Energy
Produção Nacional
Revisado por pares
Laura Gomes Nunes Melo, Paulo Henrique Morales, Karla Rezende Guerra Drummond, Deborah Conte Santos, Marcela Pizarro, Bianca Senger Vasconcelos Barros, Tessa Cerqueria Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Franz Schubert Lopes Leal, Fernando Korn Malerbi, Marília Brito Gomes,
Diabetic retinopathy is the leading cause of blindness in economically active populations. The aims of this study were to estimate the prevalence and to identify risk factors for diabetic retinopathy in patients with type 1 diabetes in Brazil. This was a nationwide, cross-sectional study conducted between August 2010 and August 2014. The study included 1760 patients with type 1 diabetes. Patients underwent a standard questionnaire, clinical and laboratory analyses and were screened for diabetic ...
Tópico(s): Chronic Kidney Disease and Diabetes
2018 - BioMed Central | BMC Public Health
Produção Nacional
Revisado por pares
Laura Gomes Nunes Melo, Paulo Henrique Morales, Karla Rezende Guerra Drummond, Deborah Conte Santos, Marcela Pizarro, Bianca Senger Vasconcelos Barros, Tessa Cerqueria Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Franz Schubert Lopes Leal, Luiza Harcar Muniz, Fernando Korn Malerbi, Marília Brito Gomes,
Objective: Cardiovascular disease, the leading cause of death worldwide, and diabetic retinopathy, the main cause of blindness in economically active populations, share clinical risk factors and pathophysiological features. The aim of this study is to examine the association between diabetic retinopathy, cardiovascular disease, and common risk factors in patients with type 1 diabetes. Design and Methods: This nested case-control study was performed in patients from the Brazilian Type 1 Diabetes ...
Tópico(s): Diabetes and associated disorders
2019 - Frontiers Media | Frontiers in Endocrinology
Produção Nacional
Revisado por pares
Victor S. Pinheiro, Felipe M. Souza, Tuani C. Gentil, Aline N. Nascimento, Paula Böhnstedt, Luanna S. Parreira, Edson C. Paz, Peter Hammer, Mirela Inês de Sairre, Bruno Lemos Batista, Mauro C. Santos,
In this work electrocatalysts based on Pd and Sn nanoparticles supported on Vulcan XC-72 carbon black with a reduced amount of Pd were prepared. We evaluated its electrocatalytic activity for ethanol oxidation reaction (EOR) in alkaline direct ethanol fuel cells (ADEFCs). The electrocatalysts were synthesized in different Pd:Sn mass ratios (1:3, 1:1, 3:1 and 1:0) on the carbon containing 20 wt % of metal. The XRD patterns of the electrocatalysts revealed an alloy formation between Pd and Sn, and the ...
Tópico(s): Advanced battery technologies research
2020 - Elsevier BV | Renewable Energy
Produção Nacional
Revisado por pares
Victor S. Pinheiro, Felipe M. Souza, Tuani C. Gentil, Aline N. Nascimento, Luanna S. Parreira, Mirela Inês de Sairre, Bruno Lemos Batista, Mauro C. Santos,
Fuel cells are important energy conversion devices. However, challenges in this regard are still noted, such as low electrocatalyst efficiencies in the oxygen reduction reaction (ORR), which occurs slowly in electrocatalyst cathodes. In this sense, this study aimed to synthetize hybrid binary and ternary electrocatalysts formed by palladium and platinum alloy nanoparticles and ceria nanorods (CeO2 NR) supported on carbon black Vulcan XC-72 (PdxPty/Vn and (Pd3Pt1)x(CeO2 NR)y(Vn)z) for the study of the ...
Tópico(s): Fuel Cells and Related Materials
2021 - Elsevier BV | Journal of Alloys and Compounds
Produção Nacional
Revisado por pares
Danielle Elis Garcia Furuya, Lingfei Ma, Mayara Maezano Faita Pinheiro, Felipe David Georges Gomes, Wesley Nunes Gonçalvez, José Marcato, Diego de Castro Rodrigues, Maria Carolina Blassioli‐Moraes, Mirian Fernandes Furtado Michereff, Miguel Borges, Raúl Alberto Alaumann, Ednaldo José Ferreira, Lucas Prado Osco, Ana Paula Marques Ramos, Jonathan Li, Lúcio André de Castro Jorge,
Accurately detecting the insect damage caused in plants might reduce losses in crop yields. Hyperspectral data is a well-accepted data source to attend this issue. However, due to their high dimensional, both robust and intelligent methods are required to extract information from these datasets. Therefore, we explore the processing of hyperspectral data with artificial intelligence methods joined with clustering techniques to detect insect herbivory damage in maize plants. We measured the leaf spectral ...
Tópico(s): Smart Agriculture and AI
2021 - Elsevier BV | International Journal of Applied Earth Observation and Geoinformation
Produção Nacional
Revisado por pares
Victor S. Pinheiro, Felipe M. Souza, Tuani C. Gentil, Luanna S. Parreira, Bruno Lemos Batista, Mauro C. Santos,
Fossil fuel alternatives are being increasingly studied, and alkaline direct ethanol fuel cells (ADEFC) have acquired importance, as to ethanol is a renewable fuel. In this context, the aims of the present study were to synthesize, characterize and evaluate electrocatalytic activity in oxygen reduction reaction (ORR) and ethanol oxidation reaction (EOR) using hybrid electrocatalysts based on Pd nanoparticles and CeO2 nanorods supported on carbon black for application in ADEFC. The highest OCV, maximum ...
Tópico(s): Fuel Cells and Related Materials
2021 - Elsevier BV | International Journal of Hydrogen Energy
Produção Nacional
Revisado por pares
Rodrigo Nascimento Pinheiro, Felipe José Fernández Coimbra, Wilson Luiz da Costa, Héber Salvador de Castro Ribeiro, Reitan Ribeiro, Alberto Julius Alves Wainstein, Gustavo Andreazza Laporte, MANOEL JESUS PINHEIRO COELHO-JR, Paulo Henrique de Sousa Fernandes, Eduardo Zanella Cordeiro, Bruno José Queiroz Sarmento, Marco Guimarães-Filho, Marciano Anghinoni, Glauco Baiocchi, Alexandre Ferreira Oliveira,
ABSTRACT Objective: to suggest a script for surgical oncology assistance in COVID-19 pandemic in Brazil. Method: a narrative review and a “brainstorming” consensus were carried out after discussion with more than 350 Brazilian specialists and renowned surgeons from Portugal, France, Italy and United States of America. Results: consensus on testing for COVID-19: 1- All patients to be operated should be tested between 24 and 48 before the procedure; 2- The team that has contact with sick or symptomatic ...
Tópico(s): Disaster Response and Management
2020 - Brazilian College of Surgeons | Revista do Colégio Brasileiro de Cirurgiões
Produção Nacional
Revisado por pares
Priscila Cunha Nascimento, Maria Karolina Martins Ferreira, Karolyny Martins Balbinot, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro, Felipe Martins Silveira, Manoela Domingues Martins, Maria Elena Crespo‐López, Rafael Rodrigues Lima,
Tópico(s): Air Quality and Health Impacts
2020 - Springer Science+Business Media | Biological Trace Element Research
Produção Nacional
Revisado por pares
Gustavo Neves de Araújo, Anderson Donelli da Silveira, Fernando Luís Scolari, Julia Luchese Custódio, Felipe Pereira Lima Marques, Rafael Coimbra Ferreira Beltrame, Willian Roberto Menegazzo, Guilherme Pinheiro Machado, Felipe Costa Fuchs, Sandro Cadaval Gonçalves, Rodrigo Vugman Wainstein, Tiago Luiz Luz Leiria, Marco Vugman Wainstein,
Background: Early risk stratification is essential for in-hospital management of ST-segment–elevation myocardial infarction. Acute heart failure confers a worse prognosis, and although lung ultrasound (LUS) is recommended as a first-line test to assess pulmonary congestion, it has never been tested in this setting. Our aim was to evaluate the prognostic ability of admission LUS in patients with ST-segment–elevation myocardial infarction. Methods: LUS protocol consisted of 8 scanning zones and was ...
Tópico(s): Radiology practices and education
2020 - Lippincott Williams & Wilkins | Circulation Cardiovascular Imaging
Produção Nacional
Revisado por pares
Róbson Ricardo Teixeira, Patrícia Fernanda Felipe Pinheiro, Luiz C. A. Barbosa, José Walkimar de M. Carneiro, Giuseppe Forlani,
A statistical model, built using the CODESSA software package, was developed to describe the relationship between the structure of nostoclide derivatives and their ability to interfere with the electron transport chain in the Hill reaction.A QSAR treatment was carried out on a series of compounds designed using the naturally occurring toxin nostoclides to correlate molecular descriptors with their in vitro biological activity (the ability to interfere with light-driven reduction of ferricyanide by ...
Tópico(s): Plant biochemistry and biosynthesis
2009 - Wiley | Pest Management Science
Produção Nacional
Revisado por pares
Tânia Mara Segatelli, C. C. D. Almeida, Patrícia Fernanda Felipe Pinheiro, M. Martinez, Carlos Roberto Padovani, Francisco Eduardo Martinez,
The Mongolian gerbil (Meriones unguiculatus) is a small rodent native to the arid regions of Mongolia and Northeastern China. The present study provides descriptions of both the cellular associations of the seminiferous-epithelium cycle and relative frequencies of stages in the gerbil. Based on the development of the acrosomic system and the nuclear morphology changes using the PAS-H staining technique, the transformation of spermatids into spermatozoa was divided into 15 steps. The first 12 steps ...
Tópico(s): Hormonal and reproductive studies
2002 - Elsevier BV | Tissue and Cell
Produção Nacional
Revisado por pares
Patrícia Fernanda Felipe Pinheiro, C. C. D. Almeida, Tânia Mara Segatelli, M. Martinez, Carlos Roberto Padovani, F. E. Martinez,
Abstract The urethra is the main place of entry for sexually transmitted pathogens. However, there is little literature on the morphology of the urogenital system, principally the urethra and ducts of the sex accessory glands. The Mongolian gerbil is an insectivorous, herbivorous and monogamous rodent with nocturnal habits; it has been used successfully as a laboratory animal since the 1960s. Therefore, the objective of the present paper was to describe the structure and ultrastructure of the urethra ...
Tópico(s): Sperm and Testicular Function
2003 - Wiley | Journal of Anatomy
Produção Nacional
Revisado por pares
M. Martinez, S. Macera, Gérson Francisco de Assis, Patrícia Fernanda Felipe Pinheiro, C. C. D. Almeida, Luís Fernando Tirapelli, Otávio Augusto Martins, Wílson de Mello Júnior, Carlos Roberto Padovani, Francisco Eduardo Martinez,
Chronic exposure to ethanol may results in pathophysiologic changes in cellular function. The present work was designed to investigate the morphology of testis submitted to experimental ethanol ingestion. Experimental animals were divided into two groups. The control group (n = 23) received a solid diet and tap water and the alcoholic group (n = 23) received the same solid diet and ethanol P.A. diluted 20% in water (v/v). After 120 days of treatment, all animals were anesthetized, weighed and sacrificed. ...
Tópico(s): Cholesterol and Lipid Metabolism
2008 - Elsevier BV | Tissue and Cell
Produção Nacional
Wellerson Rodrigo Scarano, Fabíola Choqueta de Toledo, Marina Trevizan Guerra, Patrícia Fernanda Felipe Pinheiro, Raquel Fantin Domeniconi, Sérgio Luís Felisbino, Silvana G. P. Campos, Sebastião Roberto Taboga, Wilma De Grava Kempinas,
The potential adverse reproductive effects, with emphasis on the epididymis, of in utero and lactational exposure to 100 mg/kg/d di-n-butyl phthalate (DBP) in adult male rat offspring were investigated. The fetal testis histopathology was also determined. The selected endpoints included reproductive organ weights, sperm motility and morphology, sperm epididymal transit time, sperm quantity in the testis and epididymis, hormonal status, fetal testis and epididymal histopathology and stereology, and ...
Tópico(s): Chemical Analysis and Environmental Impact
2010 - Taylor & Francis | Journal of Toxicology and Environmental Health
Produção Nacional
Revisado por pares
Valdinar S. Ribeiro, Felipe Pinheiro de Figueiredo, Antônio Augusto Moura da Silva, Heloísa Bettiol, Rosângela Fernandes Lucena Batista, Liberata Campos Coimbra, Zeni Carvalho Lamy, Marco Antônio Barbieri,
The objective of the present study was to investigate factors associated with cesarean sections in two cities located in different regions of Brazil and to determine factors that explain the higher cesarean section rate in the more developed city, Ribeirão Preto, compared to the less developed one, São Luís. Data from two cohort studies comprising 2846 women in Ribeirão Preto in 1994, and 2443 women in São Luís in 1997/1998 were used. Adjusted and non-adjusted risk estimates were calculated using ...
Tópico(s): Maternal and Neonatal Healthcare
2007 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Liberata Campos Coimbra, Felipe Pinheiro de Figueiredo, Antônio Augusto Moura da Silva, Marco Antônio Barbieri, Heloísa Bettiol, A.J.M. Caldas, Elba Gomide Mochel, Valdinar S. Ribeiro,
Data for two birth cohorts from two Brazilian municipalities, Ribeirão Preto in 1994 and São Luís in 1997/1998, were used to identify and compare factors associated with inadequate utilization of prenatal care and to identify factors capable of explaining the differences observed between the two cities. Prenatal care was defined as adequate or inadequate according to the recommendations of the Brazilian Ministry of Health. The chi-square test and Poisson regression were used to compare differences ...
Tópico(s): Breastfeeding Practices and Influences
2007 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Luiz Gustavo de Almeida Chuffa, João Paulo de Arruda Amorim, Giovana Rampazzo Teixeira, Leonardo de Oliveira Mendes, Beatriz Aparecida Fioruci, Patrícia Fernanda Felipe Pinheiro, Fábio Rodrigues Ferreira Seiva, E.L.B. Novelli, Wílson Mello Júnior, M. Martinez, Francisco Eduardo Martinez,
Melatonin regulates the reproductive cycle, energy metabolism and may also act as a potential antioxidant indoleamine. The present study was undertaken to investigate whether long-term melatonin treatment can induce reproductive alterations and if it can protect ovarian tissue against lipid peroxidation during ovulation. Twenty-four adult female Wistar rats, 60 days old (± 250-260 g), were randomly divided into two equal groups. The control group received 0.3 mL 0.9% NaCl + 0.04 mL 95% ethanol as vehicle, ...
Tópico(s): Birth, Development, and Health
2011 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Wagner José Fávaro, Giovana Rampazzo Teixeira, João PA Amorim, Leonardo de Oliveira Mendes, Beatriz Aparecida Fioruci, Patrícia Fernanda Felipe Pinheiro, Ana Angélica Henrique Fernandes, Janete AA Franci, Flávia Karina Delella, Marcelo Martinez, Francisco Eduardo Martinez,
Abstract Background Melatonin is associated with direct or indirect actions upon female reproductive function. However, its effects on sex hormones and steroid receptors during ovulation are not clearly defined. This study aimed to verify whether exposure to long-term melatonin is able to cause reproductive hormonal disturbances as well as their role on sex steroid receptors in the rat ovary, oviduct and uterus during ovulation. Methods Twenty-four adult Wistar rats, 60 days old (+/- 250 g) were randomly ...
Tópico(s): Hypothalamic control of reproductive hormones
2011 - BioMed Central | Reproductive Biology and Endocrinology
Produção Nacional
Revisado por pares
Luiz Gustavo de Almeida Chuffa, João Paulo de Arruda Amorim, Giovana Rampazzo Teixeira, Leonardo de Oliveira Mendes, Beatriz Aparecida Fioruci, Patrícia Fernanda Felipe Pinheiro, Fábio Rodrigues Ferreira Seiva, Ethel Lourenzi Barbosa Novelli, Wílson de Mello Júnior, Marcelo Martinez, Camila C.D. Almeida-Francia, Francisco Eduardo Martinez,
Chronic ethanol intake leads to reproductive damage including reactive oxygen species formation, which accelerates the oxidative process. Melatonin is known to regulate the reproductive cycle, food/liquid intake, and it may also act as a potent antioxidant indoleamine. The aim of this study was to verify the effects of alcoholism and melatonin treatment on overall feed efficiency and to analyze its protective role against the oxidative stress in the ovarian tissue of UChB rats (submitted to 10% [v/ ...
Tópico(s): Birth, Development, and Health
2011 - Wiley | Alcoholism Clinical and Experimental Research