
Nereu Augusto Streck, Fernanda Schneider, Galileo Adeli Buriol,
Solar heating of soil by mulching with transparent polyethylene (known as soil solarization) is a physical method of soil disinfestation. The increase in soil temperature by solarization inside a plastic greenhouse in Santa Maria, Rio Grande do Sul State, Brazil, was measured. It was estimated the time which soil temperature exceeded some thermal levels in solarized soil, During the 1992/1993 and 1993/1994 summers, experiments were carried out in a 10 m × 25 m plastic greenhouse. Soil temperature was ...
Tópico(s): Plant Virus Research Studies
1996 - Elsevier BV | Agricultural and Forest Meteorology

José Fernandes Barbosa Neto, Rodrigo Rodrigues Matiello, F. I. F. de Carvalho, João M. S. Oliveira, Diego Girardi Pegoraro, Fernanda Schneider, Maria Elena Basilio Sordi, Elton Vacaro,
As cultivares de aveia-branca (Avena sativa L.) cultivadas no sul do Brasil até princípios da década de 80 eram provenientes do Uruguai e da Argentina, apresentando problemas de adaptação ao ambiente de cultivo. A partir dos anos 70, programas de melhoramento começaram a produzir suas próprias populações segregantes, possibilitando o lançamento em escala comercial de cerca de 35 cultivares. Com o objetivo de estimar o progresso genético nos programas de melhoramento de aveia-branca do sul do Brasil, ...
Tópico(s): Genetics and Plant Breeding
2000 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira

Nereu Augusto Streck, Fernanda Schneider, Galileo Adeli Buriol, Arno Bernardo Heldwein,
The effect of soil mulching with transparent, black, white, and co-extruded white-on-black polyethylene sheets on soil temperature and tomato yield was evaluated in the Subtropical Central Region of the Rio Grande do Sul State, Brazil. The experiment was carried out from August 21, 1994 to December 2, 1994 in a 10m x 25m nonheated plastic greenhouse located at the county of Santa Maria. Highest soil temperatures were obtained under transparent mulch. Maximum amplitude of soil temperature waves was ...
Tópico(s): Growth and nutrition in plants
1995 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
AM Nieß, Wilhelm Bloch, Birgit Friedmann‐Bette, Casper Grim, M.P. Halle, Anja Hirschmüller, Christoph Kopp, Tim Meyer, Josef Niebauer, Claus Reinsberger, K. Röcker, Jürgen Scharhag, Johannes Scherr, Cristina Fernanda Schneider, Jürgen M. Steinacker, Axel Urhausen, Bernd Wolfarth, Florian Mayer,
Tópico(s): Cardiovascular Effects of Exercise
2020 - | German Journal of Sports Medicine

Fernanda Schneider, Karine Marcotte, Amélie Brisebois, Sabrine Amaral Martins Townsend, Anderson Dick Smidarle, Fernanda Loureiro, Alexandre da Rosa Franco, Ricardo Bernardi Soder, Alexandre Nikolaev, Luiz Carlos Porcello Marrone, Lilian Cristine Hübner,
Background A growing body of literature has demonstrated the importance of discourse assessment in patients who suffered from brain injury, both in the left and right hemispheres, as discourse represents a key component of functional communication. However, little is known about the relationship between gray matter density and macrolinguistic processing. Purpose This study aimed to investigate this relationship in a group of participants with middle-low to low socioeconomic status. Method Twenty ...
Tópico(s): Action Observation and Synchronization
2021 - American Speech–Language–Hearing Association | Journal of Speech Language and Hearing Research

Geisson Marcos Nardi, Adriana Graziele Farias Januario, Cássio Geremia Freire, Fernanda Megiolaro, Kétlin Schneider, Marlene Raimunda Andreola Perazzoli, Scheley Raap Do Nascimento, Ana Cristina Gon, Luísa Nathália Bolda Mariano, Glauber Wagner, Rivaldo Niero, Claudriana Locatelli,
... Nardi, Adriana Graziele Farias Januario, Cassio Geremia Freire, Fernanda Megiolaro, Kétlin Schneider, Marlene Raimunda Andreola Perazzoli, Scheley Raap Do Nascimento, Ana Cristina Gon, Luísa Nathália Bolda Mariano, Glauber Wagner, Rivaldo Niero, and Claudriana Locatelli Author(s) affiliations:Geisson Marcos Nardi1, Adriana Graziele Farias Januario1, Cassio Geremia Freire2, Fernanda Megiolaro2, Ketlin Schneider2, Marlene Raimunda Andreola Perazzoli2, Scheley ...
Tópico(s): Phytochemical and Pharmacological Studies
2016 - Medknow | Pharmacognosy Research

Laurita Boff, Jennifer Munkert, Flaviano Melo Ottoni, Naira Fernanda Zanchett Schneider, Gabriela Silva Ramos, Wolfgang Kreis, Saulo Fernandes de Andrade, José Dias de Souza Filho, Fernão Castro Braga, Ricardo José Alves, Rodrigo Maia de Pádua, Cláudia Maria Oliveira Simões,
In recent years, new therapeutic possibilities were proposed for cardiac glycosides traditionally used to treat heart diseases, such as anticancer and antiviral activities. In this sense, this work aimed to synthesize the readily accessible 3β-azido-3-deoxydigitoxigenin (5) from digitoxigenin (1). Two new series of compounds were obtained from derivative (5): (i) O-glycosyl trizols through click chemistry with propargyl glycosides; and (ii) compounds substituted in the alpha carbonyl position with different ...
Tópico(s): Phytochemical compounds biological activities
2019 - Elsevier BV | European Journal of Medicinal Chemistry

Cíntia Lhullier, M. I. G. Moritz, E. O. Tabalipa, F. N. Sardá, Naira Fernanda Zanchett Schneider, Milene Höehr de Moraes, Larissa Constantino, Flávio Henrique Reginatto, Mário Steindel, Ulisses dos Santos Pinheiro, Cláudia Maria Oliveira Simões, C. D. Pérez, Eloir Paulo Schenkel,
This paper reports the in vitro antiproliferative effects, antiprotozoal, anti-herpes and antimicrobial activities of 32 organic extracts of 14 marine sponges and 14 corals collected in northeast Brazilian coast. The ethanolic extracts of the sponges Amphimedon compressa and Tedania ignis, and the acetone extract of Dysidea sp. showed relevant results concerning the antiproliferative effects against A549, HCT-8, and PC-3 cell lines by sulforhodamine B assay, but also low specificity. Concerning ...
Tópico(s): Aquaculture disease management and microbiota
2019 - Instituto Internacional de Ecologia (Brazil) | Brazilian Journal of Biology

Fabrício G. Sousa, Naira Fernanda Zanchett Schneider, Caroline Eliza Mendes, Neusa Fernandes de Moura, Rosiane Berenice Nicoloso Denardin, Renata Matuo, Mário Sérgio Mantovani,
Abstract The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were β-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, ...
Tópico(s): Plant-Derived Bioactive Compounds
2007 - Taylor & Francis | Journal of Essential Oil Research

Naira Fernanda Zanchett Schneider, Fabiana Cristina Geller, Lara Persich, Lucas Lourenço Marostica, Rodrigo Maia de Pádua, Wolfgang Kreis, Fernão Castro Braga, Cláudia Maria Oliveira Simões,
Cardiac glycosides consist of a large family of naturally derived compounds that are clinically used to treat congestive heart failure, and also present anticancer properties. In this study, the cytotoxic effects of two cardenolides, digitoxigenin monodigitoxoside (DGX) and convallatoxin (CON) were screened in four human tumour cell lines. Both compounds showed anti-proliferative effects in all tumour cells, at nanomolar concentrations. Since the human lung cancer cell line A549 was the most sensitive, ...
Tópico(s): Steroid Chemistry and Biochemistry
2015 - Taylor & Francis | Natural Product Research

Naira Fernanda Zanchett Schneider, Claudia Cerella, Cláudia Maria Oliveira Simões, Marc Diederich,
Cardiac glycosides (CGs) are natural compounds widely used in the treatment of several cardiac conditions and more recently have been recognized as potential antitumor compounds. They are known to be ligands for Na/K-ATPase, which is a promising drug target in cancer. More recently, in addition to their antitumor effects, it has been suggested that CGs activate tumor-specific immune responses. This review summarizes the anticancer aspects of CGs as new strategies for immunotherapy and drug repositioning ( ...
Tópico(s): Biochemical and Molecular Research
2017 - Multidisciplinary Digital Publishing Institute | Molecules

Naira Fernanda Zanchett Schneider, Lara Persich, Sayonarah C. Rocha, Ana Carolina Ramos, Vanessa Faria Cortes, Izabella Thaís Silva, Jennifer Munkert, Rodrigo Maia de Pádua, Wolfgang Kreis, Alex Gutterres Taranto, Leandro A. Barbosa, Fernão Castro Braga, Cláudia Maria Oliveira Simões,
Cardiac glycosides (CGs) are natural compounds widely used to treat several cardiac conditions and more recently have been recognized as potential antitumor agents. They are known as Na,K-ATPases ligands, which is a promising drug target in cancer. In this study, the short and long-lasting cytotoxic effects of the natural cardenolide digitoxigenin monodigitoxoside (DGX) were evaluated against two non-small cell lung cancer lines (A549 and H460 cells). It was found that DGX induced cytotoxic effects ...
Tópico(s): ATP Synthase and ATPases Research
2017 - Elsevier BV | Biomedicine & Pharmacotherapy

Naira Fernanda Zanchett Schneider, Claudia Cerella, Jin‐Young Lee, Aloran Mazumder, Kyung Rok Kim, Annelise De Carvalho, Jennifer Munkert, Rodrigo Maia de Pádua, Wolfgang Kreis, Kyu‐Won Kim, Christo Christov, Mario Dicato, Hyun‐Jung Kim, Byung Woo Han, Fernão Castro Braga, Cláudia Maria Oliveira Simões, Marc Diederich,
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoevatromonoside (GEV) out of 46 CGs for its low nanomolar anti-lung cancer activity. GEV presented reduced toxicity towards non-cancerous cell types (lung MRC-5 and PBMC) and high-affinity binding to the Na+/K+-ATPase alpha subunit, assessed by computational ...
Tópico(s): Bioactive Natural Diterpenoids Research
2018 - Frontiers Media | Frontiers in Pharmacology

Jennifer Munkert, Marina Santiago Franco, Elke Nolte, Izabella Thaís Silva, Rachel Oliveira Castilho, Flaviano Melo Ottoni, Naira Fernanda Zanchett Schneider, Mônica Cristina Oliveira, Helge Täubert, Walter Bauer, Saulo Fernandes de Andrade, Ricardo José Alves, Cláudia Maria Oliveira Simões, Fernão Castro Braga, Wolfgang Kreis, Rodrigo Maia de Pádua,
Abstract Recent studies demonstrate that cardiac glycosides, known to inhibit Na+/K+-ATPase in humans, have increased susceptibility to cancer cells that can be used in tumor therapy. One of the most promising candidates identified so far is glucoevatromonoside, which can be isolated from the endangered species Digitalis mariana ssp. heywoodii. Due to its complex structure, glucoevatromonoside cannot be obtained economically by total chemical synthesis. Here we describe two methods for glucoevatromonoside ...
Tópico(s): Plant biochemistry and biosynthesis
2017 - Thieme Medical Publishers (Germany) | Planta Medica

Izabella Thaís Silva, Jennifer Munkert, Elke Nolte, Naira Fernanda Zanchett Schneider, Sayonarah C. Rocha, Ana Carolina Ramos, Wolfgang Kreis, Fernão Castro Braga, Rodrigo Maia de Pádua, Alex Gutterres Taranto, Vanessa Faria Cortes, Leandro A. Barbosa, Sven Wach, Helge Täubert, Cláudia Maria Oliveira Simões,
Cardiac glycosides (CGs) are natural compounds used to treat congestive heart failure. They have garnered attention as a potential cancer treatment option, especially because they bind to Na+/K+-ATPase as a target and activate intracellular signaling pathways leading to a variety of cellular responses. In this study we evaluated AMANTADIG, a semisynthetic cardenolide derivative, for its cytotoxic activity in two human androgen-insensitive prostate carcinoma cell lines, and the potential synergistic ...
Tópico(s): Hormonal Regulation and Hypertension
2018 - Elsevier BV | Biomedicine & Pharmacotherapy

Cíntia Lhullier, Eliane de Oliveira Tabalipa, F. N. Sardá, Louis P. Sandjo, Naira Fernanda Zanchett Schneider, João Luís Carraro, Cláudia Maria Oliveira Simões, Eloir Paulo Schenkel,
The marine sponge Raspailia bouryesnaultae, collected in South Brazil, was selected for detailed investigation considering the results of a screening that pointed to an in vitro antiproliferative effect against non-small cells of human lung cancer (A549) and anti-herpes activity against Herpes Simplexvirus type 1 (KOS and 29R strains) of ethanolic extracts. The fractionation and chemical investigation of the sponge's hexanic fraction led to the isolation and structural elucidation of six clerodane ...
Tópico(s): Synthetic Organic Chemistry Methods
2019 - Multidisciplinary Digital Publishing Institute | Marine Drugs

Laurita Boff, Naira Fernanda Zanchett Schneider, Jennifer Munkert, Flaviano Melo Ottoni, Gabriela Silva Ramos, Wolfgang Kreis, Fernão Castro Braga, Ricardo José Alves, Rodrigo Maia de Pádua, Cláudia Maria Oliveira Simões,
Human herpesviruses are among the most prevalent pathogens worldwide and have become an important public health issue. Recurrent infections and the emergence of resistant viral strains reinforce the need of searching new drugs to treat herpes virus infections. Cardiac glycosides are used clinically to treat cardiovascular disturbances, such as congestive heart failure and atrial arrhythmias. In recent years, they have sparked new interest in their potential anti-herpes action. It has been previously ...
Tópico(s): Phytochemistry and Bioactive Compounds
2020 - Springer Science+Business Media | Archives of Virology

Neumar Regiane Machado Albertoni, Giane Fernanda Schneider Gross, Érica Oliveira dos Santos, Marco Aurélio Kalinke,
O presente artigo apresenta um mapeamento sistemático (MS) realizado a partir de teses e dissertações que contemplam a Robótica Educacional como um recurso tecnológico para a ensino de conteúdos matemáticos, evidenciando uma descrição dos trabalhos associados às metodologias de ensino e teorias nelas utilizadas. O mapeamento foi realizado pelos trabalhos disponibilizados nos periódicos da Capes, no catálogo de teses e dissertações da Capes e na Biblioteca Digital Brasileira de Teses e Dissertações ( ...
Tópico(s): Education Pedagogy and Practices
2021 - Associação Sul-Rio-Grandense de Pesquisadores em História da Educação (ASPHE) | RENOTE

Naira Fernanda Zanchett Schneider, Izabella Thaís Silva, Lara Persich, Annelise De Carvalho, Sayonarah C. Rocha, Lucas Lourenço Marostica, Ana Carolina Ramos, Alex Gutterres Taranto, Rodrigo Maia de Pádua, Wolfgang Kreis, Leandro A. Barbosa, Fernão Castro Braga, Cláudia Maria Oliveira Simões,
Tópico(s): Natural product bioactivities and synthesis
2017 - Springer Science+Business Media | Molecular and Cellular Biochemistry

Henrique Herbst Rosa, Pâmela de Carvalho, Caroline Flach Ortmann, Naira Fernanda Zanchett Schneider, Flávio Henrique Reginatto, Cláudia Maria Oliveira Simões, Izabella Thaís Silva,
Prostate cancer (PCa) is the most diagnosed invasive cancer and a leading cause of death in men in western countries. Most patients initially respond to androgen deprivation but finally develop hormone-refractory disease, which results in advanced clinical failure and death. Since hormone-refractory disease is highly radiotherapy and chemotherapy resistant, increasing interest has been placed on finding novel therapies for this advanced type of Pca. The potential cytotoxic effects of the crude extract ...
Tópico(s): NF-κB Signaling Pathways
2020 - Elsevier BV | Biomedicine & Pharmacotherapy

Pollyana Windmöller, E Bodnár, Julia Casagrande, Fernanda Dallazen, Juliana Schneider, Silvana Agnolleto Berwanger, Audrey Borghi‐Silva, Eliane Roseli Winkelmann,
BACKGROUND: Aerobic exercise and CPAP benefit patients in the postoperative period of cardiac surgery. To our knowledge, the association of aerobic exercise on an exercise bicycle with CPAP has not yet been demonstrated. Therefore, we aimed to evaluate the effectiveness of physical exercise on a cycle ergometer combined with CPAP in the postoperative period after coronary artery bypass graft surgery. METHODS: This was a randomized clinical trial, with recruitment from May 2017 to December 2017 (registered in ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2020 - American Association for Respiratory Care | Respiratory Care

Ana Lúcia Cunha Dornelles, Fernando Irajá Félix de Carvalho, Luiz Carlos Federizzi, Cristine Luise Handel, Fernanda Bered, Maria Elena Basilio Sordi, Fernanda Schneider,
In order to determine the in vitro behavior of Brazilian triticale, 16 triticale genotypes, and three wheat genotypes used as checks, were sown in June 1994. The explants used were immature embryos. In addition to the genotype tests, two culture media for callus induction were also evaluated, i.e., MS (Murashige and Skoog, Physiol. Plant. 15: 473-497, 1962) medium containing 2.0 mg 2,4D/l, and MS medium containing 4.0 mg 2,4D/l. The plant regeneration protocol used was the one employed at the Laboratório ...
Tópico(s): Turfgrass Adaptation and Management
1997 - Brazilian Society of Genetics | Brazilian Journal of Genetics

Geocleber Gomes de Sousa, Henderson Castelo Sousa, Carla Ingryd Nojosa Lessa, Geovana Ferreira Goes, Márcio Henrique da Costa Freire, Maria Vanessa Pires de Souza, Silas Prímola Gomes, Fernanda Schneider,
ABSTRACT Salt stress affects the production of watermelon (Citrullus lanatus) seedlings. However, substrates with alternative materials in their composition can mitigate the harmful effects on the formation of watermelon seedlings. Thus, the objective of the present study was to evaluate the emergence and production of watermelon seedlings grown in different substrates under salt stress. The research was conducted in an agricultural greenhouse belonging to the Universidade da Integração Internacional ...
Tópico(s): Soil Management and Crop Yield
2023 - UNIVERSIDADE FEDERAL DE CAMPINA GRANDE | Revista Brasileira de Engenharia Agrícola e Ambiental

Lamine Sanó, Laís Lacerda Brasil de Oliveira, Maria Dalila Martins Leão, João Evangelista de Ávila dos Santos, Suelen Carneiro de Medeiros, Fernanda Schneider, Alan Bernard Oliveira de Sousa, Carlos Alberto Kenji Taniguchi, Celli Rodrigues Muniz, Thalles B. Grangeiro, Christiana de Fátima Bruce da Silva,
The use of growth-promoting microorganisms with biostimulant characteristics is an important biological asset for the acclimatization of micropropagated seedlings. The present study aimed to evaluate the efficacy of the application of Trichoderma spp. on the promotion of the growth of micropropagated banana seedlings during acclimatization. The experiment was performed in an 8 × 6 completely randomized design using the following treatments: water, seedlings fertilized with controlled-release fertilizer, ...
Tópico(s): Growth and nutrition in plants
2022 - Elsevier BV | Plant Physiology and Biochemistry

Leonardo Manir Feitosa, Ana Paula Barbosa Martins, Tommaso Giarrizzo, Wagner Macedo, Iann Leonardo Pinheiro Monteiro, Romário Gemaque, Jorge Luíz Silva Nunes, Fernanda P. Gomes, Horácio Schneider, Iracilda Sampaio, Rosália Furtado Cutrim Souza, João Bráullio de Luna Sales, Luis Fernando da Silva Rodrigues‐Filho, Lígia Tchaicka, Luís Fernando Carvalho-Costa,
Here, we report trading of endangered shark species in a world hotspot for elasmobranch conservation in Brazil. Data on shark fisheries are scarce in Brazil, although the northern and northeastern regions have the highest indices of shark bycatch. Harvest is made primarily with processed carcasses lacking head and fins, which hampers reliable species identification and law enforcement on illegal catches. We used partial sequences of two mitochondrial genes (COI and/or NADH2) to identify 17 shark ...
Tópico(s): Fish Biology and Ecology Studies
2018 - Nature Portfolio | Scientific Reports

Luísa Fernanda Habigzang, Jaluza Aimèe Schneider, Rafaela Petroli Frizzo, Clarissa Pinto Pizarro de Freitas,
Domestic violence against women constitutes a serious public health problem, which requires effective interventions for its prevention and treatment. This study aimed to develop and evaluate an intervention protocol, based on cognitive-behavioral therapy, for women in situations of domestic violence. The sample was composed of 11 women that were victims of psychological, physical, and/or sexual violence perpetrated by their partners. Symptoms of anxiety, depression, stress and post-traumatic stress ...
Tópico(s): Resilience and Mental Health
2018 - Pontifical Xavierian University | Universitas Psychologica
Sebastian Maurer‐Stroh, Manfred Koranda, Wolfgang Benetka, Georg Schneider, Fernanda L. Sirota, Frank Eisenhaber,
Three different prenyltransferases attach isoprenyl anchors to C-terminal motifs in substrate proteins. These lipid anchors serve for membrane attachment or protein–protein interactions in many pathways. Although well-tolerated selective prenyltransferase inhibitors are clinically available, their mode of action remains unclear since the known substrate sets of the various prenyltransferases are incomplete. The Prenylation Prediction Suite (PrePS) has been applied for large-scale predictions of prenylated ...
Tópico(s): Peptidase Inhibition and Analysis
2007 - Public Library of Science | PLoS Computational Biology
Sebastian Maurer‐Stroh, Masaki Gouda, Maria Novatchkova, Alexander Schleiffer, Georg Schneider, Fernanda L. Sirota, Michael Wildpaner, Nobuhiro Hayashi, Frank Eisenhaber,
We evaluated the evolutionary conservation of glycine myristoylation within eukaryotic sequences. Our large-scale cross-genome analyses, available as MYRbase, show that the functional spectrum of myristoylated proteins is currently largely underestimated. We give experimental evidence for in vitro myristoylation of selected predictions. Furthermore, we classify five membrane-attachment factors that occur most frequently in combination with, or even replacing, myristoyl anchors, as some protein family ...
Tópico(s): Alzheimer's disease research and treatments
2004 - BioMed Central | Genome biology

Raquel Oliveira, Valéria Cristina Schneider, Fernanda Salloume Sampaio Bonafé, João Marôco, Juliana Álvares Duarte Bonini Campos,
In the correctional context, occupational characteristics may contribute to the development of burnout.To compare the scores of Emotional Exhaustion (EE), Cynicism (CY) and Professional Efficacy (PE) of staff members according to occupational variables in two correctional facilities (CF1 and CF2).339 Brazilian employees from two correctional facilities completed a socio-demographic/occupational questionnaire and the Maslach Burnout Inventory-General Survey (MBI-GS). The comparison between the scores ...
Tópico(s): Healthcare professionals’ stress and burnout
2016 - IOS Press | Work

Juliana Álvares Duarte Bonini Campos, Valéria Cristina Schneider, Fernanda Salloume Sampaio Bonafé, Raquel Oliveira, João Marôco,
ABSTRACT: Objective: The aims of this study were to estimate the association between an at-risk drinking pattern and sociodemographic variables, and to compare the mean scores of the factors associated with the Burnout Syndrome, according to the alcohol consumption pattern in staff members from two Brazilian prisons. Methods: A cross-sectional study was developed with 339 participants (response rate = 63.8%). The instruments used were a sociodemographic questionnaire, the Alcohol Use Disorders Identification ...
Tópico(s): Health and Wellbeing Research
2016 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia