Produção Nacional
Eliézer Jäger, Cristina G. Venturini, Fernanda Poletto, Letícia Marques Colomé, João P. U. Pohlmann, Andressa Bernardi, Ana Maria Oliveira Battastini, Sı́lvia Stanisçuaski Guterres, Adriana Raffin Pohlmann,
Based on the structure of polymeric nanocapsules containing a lipid-dispersed core composed of caprylic/capric trygliceride (CCT) and sorbitan monostearate (SM), we hypothesized that varying the core component concentrations the drug release kinetic could be modulated. Our objective was also to determine the parameters which were responsible for controlling the drug release kinetics. The nanocapsules were prepared by interfacial deposition of poly(epsilon-caprolactone). Interfacial hydrolysis of indomethacin ...
Tópico(s): Advanced Drug Delivery Systems
2009 - American Scientific Publishers | Journal of Biomedical Nanotechnology
Produção Nacional
Revisado por pares
Francine Perri Venturini, Fernanda Dias de Moraes, Lucas Ribeiro Xavier Cortella, Priscila Adriana Rossi, Claudinei da Cruz, Gilberto Moraes,
Tópico(s): Fish Biology and Ecology Studies
2014 - Springer Science+Business Media | Fish Physiology and Biochemistry
Produção Nacional
Revisado por pares
Inês Soares, Érico Silva Loreto, Luana Rossato, Débora Nunes Mário, Tarcieli Pozzebon Venturini, Fernanda Giesel Baldissera, Jânio Morais Santúrio, Sydney Hartz Alves,
In the present study, the antifungal activity of essential oils obtained from Origanum vulgare (oregano), Cinnamomum zeylanicum (cinnamon), Lippia graveolens (Mexican oregano), Thymus vulgaris (thyme), Salvia officinalis (sage), Rosmarinus officinalis (rosemary), Ocimum basilicum (basil) and Zingiber officinale (ginger) were assessed against Candida glabrata isolates. One group contained 30 fluconazole-susceptible C. glabrata isolates, and the second group contained fluconazole-resistant isolates derived ...
Tópico(s): Plant Pathogens and Fungal Diseases
2015 - Elsevier BV | Journal de Mycologie Médicale
Produção Nacional
Revisado por pares
Andressa Monteiro Venturini, Fernanda Mancini Nakamura, Júlia Brandão Gontijo, Aline Giovana da França, Caio Augusto Yoshiura, Jéssica Adriele Mandro, Siu Mui Tsai,
Studies in the Amazon are being intensified to evaluate the alterations in the microbial communities of soils and sediments in the face of increasing deforestation and land-use changes in the region. However, since these environments present highly heterogeneous physicochemical properties, including contaminants that hinder nucleic acids isolation and downstream techniques, the development of best molecular practices is crucial. This work aimed to optimize standard protocols for DNA extraction and ...
Tópico(s): Molecular Biology Techniques and Applications
2020 - Elsevier BV | Heliyon
Produção Nacional
Revisado por pares
Francieli Chassot, Tarcieli Pozzebon Venturini, Fernanda Baldissera Piasentin, Luana Rossato, Adriana Fiorini, Terezinha Inez Estivalet Svidzinski, Sydney Hartz Alves,
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2016 - Springer Science+Business Media | Mycopathologia
Produção Nacional
Revisado por pares
Francine Perri Venturini, Fernanda Dias de Moraes, Priscila Adriana Rossi, Ive Marchioni Avilez, Natália Sayuri Shiogiri, Gilberto Moraes,
Tópico(s): Parasite Biology and Host Interactions
2018 - Springer Science+Business Media | Fish Physiology and Biochemistry
Produção Nacional
Revisado por pares
Francieli Chassot, Tarcieli Pozzebon Venturini, Fernanda Baldissera Piasentin, Jânio Morais Santúrio, Terezinha Inez Estivalet Svidzinski, Sydney Hartz Alves,
Candida parapsilosis may acquire resistance to echinocandins, a fact that prompts the search for new therapeutic options.The present study aimed to evaluate the in vitro activity of antifungal agents, alone and in combination, against four groups of C. parapsilosis strains: (1) echinocandin-susceptible (ES) clinical isolates (MIC ≤ 2μg/ml), (2) anidulafungin-resistant strains (MIC ≥ 8μg/ml), (3) caspofungin-resistant strains (MIC ≥ 8μg/ml), and (4) micafungin-resistant strains (MIC ≥ 8μg/ml).Antifungal interactions ...
Tópico(s): Nail Diseases and Treatments
2019 - Elsevier BV | Revista Iberoamericana de Micología
Produção Nacional
Revisado por pares
Annelyse Araújo Pereira, Sandra Márcia Castro, Ranielly Ribeiro Venturini, Fernanda Oliveira César, Patrícia Marques Fortes, Paulo Sucasas Costa,
A 30-day-old female infant presented to the orthopedic emergency department with progressive upper limb paralysis over the last week, with no history of trauma or fever. She was born at term, cesarean delivery, with unremarkable physical examination at birth. The mother had adequate prenatal care, but the last trimester venereal disease research laboratory test result was not available. The infant had a markedly decreased spontaneous movement of the upper limbs, crying on active movement, with intense ...
Tópico(s): Female Genital Mutilation/Cutting Issues
2017 - Elsevier BV | The Journal of Pediatrics
Produção Nacional
Revisado por pares
Rinaldo Pôncio Mendes, Ricardo de Souza Cavalcante, Sílvio Alencar Marques, Mariângela Esther Alencar Marques, James Venturini, Tatiane Fernanda Sylvestre, Anamaria Mello Miranda Paniago, Ana Carla Pereira, Julhiany de Fátima da Silva, Alexandre Todorovic Fabro, Sandra de Moraes Gimenes Bosco, Eduardo Bagagli, Rosane Christine Hahn, Adriele Dandara Levorato,
Background: This review article summarizes and updates the knowledge on paracoccidioidomycosis. P lutzii and the cryptic species of P. brasiliensis and their geographical distribution in Latin America, explaining the difficulties observed in the serological diagnosis. Objectives: Emphasis has been placed on some genetic factors as predisposing condition for paracoccidioidomycosis. Veterinary aspects were focused, showing the wide distribution of infection among animals. The cell-mediated immunity ...
Tópico(s): T-cell and Retrovirus Studies
2017 - Bentham Science Publishers | The Open Microbiology Journal
Produção Nacional
Revisado por pares
Catiúscia Padilha de Oliveira, Cristina G. Venturini, Bruna Donida, Fernanda Poletto, Sı́lvia Stanisçuaski Guterres, Adriana Raffin Pohlmann,
Aqueous solutions of lipid-core nanocapsules are interesting drug delivery systems for passive drug targeting. In this study, we hypothesized that the drug distribution mechanisms in lipid-core nanocapsule formulations could be categorized into six different types. To experimentally determine the type of drug distribution in these formulations, we proposed the use of an algorithm as an innovative strategy. The approach is shown to be a valuable tool to optimize and select formulations intended for ...
Tópico(s): Protein Interaction Studies and Fluorescence Analysis
2012 - Royal Society of Chemistry | Soft Matter
Produção Nacional
Revisado por pares
Júlia Venturini Helaehil, Luiza Venturini Helaehil, Laryssa Fernanda Alves, Boyang Huang, Milton Santamaria, Paulo Bártolo, Guilherme Ferreira Caetano,
Critical bone defects are the most difficult challenges in the area of tissue repair. Polycaprolactone (PCL) scaffolds, associated with hydroxyapatite (HA) and tricalcium phosphate (TCP), are reported to have an enhanced bioactivity. Moreover, the use of electrical stimulation (ES) has overcome the lack of bioelectricity at the bone defect site and compensated the endogenous electrical signals. Such treatments could modulate cells and tissue signaling pathways. However, there is no study investigating ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2023 - Multidisciplinary Digital Publishing Institute | Bioengineering
Produção Nacional
Revisado por pares
Cláudia Elizabeth Volpe‐Chaves, Sandra Maria do Valle Leone de Oliveira, James Venturini, Antônio José Grande, Tatiane Fernanda Sylvestre, Rinaldo Pôncio Mendes, Anamaria Mello Miranda Paniago,
Chronic pulmonary aspergillosis (CPA) is a slow and progressive disease that develops in preexisting lung cavities of patients with tuberculosis sequelae, and it is associated with a high mortality rate. Serological tests such as double agar gel immunodiffusion test (DID) or counterimmunoelectrophoresis (CIE) test have been routinely used for CPA diagnosis in the absence of positive cultures. However, these tests have been replaced with enzyme-linked immunoassay (ELISA) and, a variety of methods. This ...
Tópico(s): Plant Pathogens and Fungal Diseases
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Fernando Augusto Malavazzi Casare, Karina Thieme, Juliana da Costa Santos Pessoa, Luciana Venturini Rossoni, Gisele Kruger Couto, Fernanda Barrinha Fernandes, Dulce Elena Casarini, Maria Oliveira‐Souza,
Chronic angiotensin II (ANG II) infusion for 1 or 2 wk leads to progressive hypertension and induces inward hypertrophic remodeling in preglomerular vessels, which is associated with increased renal vascular resistance (RVR) and decreased glomerular perfusion. Considering the ability of preglomerular vessels to exhibit adaptive responses, the present study was performed to evaluate glomerular perfusion and renal function after 6 wk of ANG II infusion. To address this study, male Wistar rats were submitted ...
Tópico(s): Renal and Vascular Pathologies
2016 - American Physical Society | AJP Renal Physiology
Produção Nacional
Revisado por pares
Álvaro de Oliveira Franco, Guilherme de Oliveira Venturini, Camila Fernanda da Silveira Alves, Rael Lopes Alves, Paul Vicuña Serrano, Letícia Ramalho, Rafaela Brugnera Tomedi, Samara Machado Bruck, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo,
Abstract Fibromyalgia is a heterogenous primary pain syndrome whose severity has been associated with descending pain modulatory system (DPMS) function and functional connectivity (FC) between pain processing areas. The brain-derived neurotrophic factor (BDNF) Val66Met single nucleotide polymorphism has been linked to vulnerability to chronic pain. In this cross-sectional imaging genetics study, we investigated fibromyalgia, the relationship between BDNF Val66Met heterozygous genotypes (Val/Met), and ...
Tópico(s): Myofascial pain diagnosis and treatment
2022 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Wagner Paris, Priscila Vincenzi dos Santos, Luís Fernando Glasenapp de Menezes, Fernando Kuss, Magali Floriano da Silveira, Bruna Boito, Tiago Venturini, Fernanda Stanqueviski,
O objetivo deste experimento foi avaliar as características da carcaça de bezerros holandeses terminados em confinamento ou em pastagem com suplementação e abatidos com diferentes pesos de abate. Os animais confinados foram alimentados com volumoso e concentrado comercial, na proporção de 40:60, sendo a silagem de milho utilizada como volumoso. O delineamento experimental foi o inteiramente casualizado, em arranjo fatorial 2x4 (dois sistemas de terminação x quatro pesos de abate). Os animais foram ...
Tópico(s): Ruminant Nutrition and Digestive Physiology
2015 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Ana Cláudia de Freitas, Gregório Miguel Ferreira de Camargo, Rusbel Raúl Aspilcueta Borquis, Nedenia Bonvino Stafuzza, Guilherme Costa Venturini, Fernanda Tanamati, Naudín Hurtado-Lugo, Carlos Castilho Barros, Humberto Tonhati,
The study of genes associated with host defense mechanisms, such as the A2M gene, plays a critical role in preventing diseases that reduce milk yield and its constituents. The aim of this study was to identify polymorphisms in the A2M gene in Murrah buffaloes (Bubalus bubalis), and investigate their associations with milk yield, fat and protein production, fat and protein percentages, and somatic cell count. Hair follicle samples of 136 animals were collected for DNA extraction, and polymorphisms ...
Tópico(s): Genetic and phenotypic traits in livestock
2016 - Research Foundation of Ribeirão Preto | Genetics and Molecular Research
Produção Nacional
Revisado por pares
Fernanda Cristina de Mesquita, Shanna Bitencourt, Eduardo Caberlon, Gabriela Venturini, Bruno Souza Basso, Júlia Schmid, Gabriela A. Ferreira, Fernanda dos Santos de Oliveira, Jarbas Rodrigues de Oliveira,
Hepatic stellate cells (HSC) play a key role in liver fibrogenesis. Activation of PPARγ and inhibition of fibrogenic molecules are potential strategies to block HSC activation and differentiation. Aware that the process of hepatic fibrosis involves inflammatory mediators, various anti-inflammatory substances have been studied in an attempt to revert fibrosis. The purpose of this study was to investigate the in vitro effects of fructose-1,6-bisphosphate (FBP) on HSC phenotype reversion. The results ...
Tópico(s): Diet, Metabolism, and Disease
2013 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Tarcieli Pozzebon Venturini, Luana Rossato, Francieli Chassot, Jéssica Tairine Keller, Fernanda Baldissera Piasentin, Jânio Morais Santúrio, Sydney Hartz Alves,
The genus Fusarium is characterized by hyaline filamentous fungi that cause infections predominantly in immunocompromised patients. The remarkable primary resistance to antifungal agents of this genus requires a search for new therapeutic possibilities. This study assessed the in vitro susceptibility of 25 clinical isolates of Fusarium against antifungal agents (amphotericin B, caspofungin, itraconazole and voriconazole) and antimicrobials (pentamidine, polymyxin B, tigecycline and tobramycin) according ...
Tópico(s): Infectious Diseases and Mycology
2016 - Microbiology Society | Journal of Medical Microbiology
Produção Nacional
Revisado por pares
Carina Duarte Venturini, Paula Engroff, Vanessa Sgnaolin, Raquel Milani El Kik, Fernanda Bueno Morrone, Irênio Gomes da Silva Filho, Geraldo Attílio De Carli,
Resumo Para descrever o perfil de consumo de nutrientes e verificar a sua associação com as variáveis sociodemográficas e de saúde, desenvolveu-se um estudo transversal, de base populacional em uma amostra aleatória de 427 idosos residentes em Porto Alegre, Brasil. O consumo alimentar foi avaliado através do Inquérito Recordatório de 24 Horas e Investigação da História Dietética. Dos idosos entrevistados, 70% eram mulheres; 48,5% possuíam entre 60 e 69 anos; 68,8% possuíam menos de 8 anos de escolaridade; ...
Tópico(s): Obesity, Physical Activity, Diet
2015 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Thais Fernanda de Campos Fraga‐Silva, Luiza Ayumi Nishiyama Mimura, Camila Martins Marchetti, Fernanda Chiuso‐Minicucci, Thaís Graziela Donegá França, Sofia Fernanda Gonçalves Zorzella-Pezavento, James Venturini, Maria Sueli Parreira de Arruda, Alexandrina Sartori,
Multiple sclerosis (MS) is an inflammatory/autoimmune disease of the central nervous system (CNS) mainly mediated by myelin specific T cells. It is widely believed that environmental factors, including fungal infections, contribute to disease induction or evolution. Even though Candida infection among MS patients has been described, the participation of this fungus in this pathology is not clear. The purpose of this work was to evaluate the effect of a Candida albicans infection on experimental autoimmune ...
Tópico(s): T-cell and B-cell Immunology
2015 - Hindawi Publishing Corporation | Journal of Immunology Research
Produção Nacional
Revisado por pares
Kyle Meyer, Andrew H. Morris, Kevin D. Webster, Ann M. Klein, Marie Kroeger, Laura Meredith, Andreas Brændholt, Fernanda Mancini Nakamura, Andressa Monteiro Venturini, Leandro Fonseca de Souza, Katherine L. Shek, Rachel E. Danielson, Joost van Haren, Plínio Barbosa de Camargo, Siu Mui Tsai, Fernando Dini Andreote, José M. S. de Mauro, Jos Barlow, Érika Berenguer, Klaus Nüsslein, S. R. Saleska, Jorge L. M. Rodrigues, Brendan J. M. Bohannan,
Amazonian rainforest is undergoing increasing rates of deforestation, driven primarily by cattle pasture expansion. Forest-to-pasture conversion has been associated with increases in soil methane (CH4) emission. To better understand the drivers of this change, we measured soil CH4 flux, environmental conditions, and belowground microbial community structure across primary forests, cattle pastures, and secondary forests in two Amazonian regions. We show that pasture soils emit high levels of CH4 (mean: ...
Tópico(s): Indigenous Studies and Ecology
2020 - Elsevier BV | Environment International
Produção Nacional
Revisado por pares
Ana Maria Antonello, Felipe Lamberti Pivoto, Giovana Camillo, Patrícia Bräunig, Luís Antônio Sangioni, Endrigo Pompermayer, M.C. Venturini, Fernanda Silveira Flôres Vogel,
ABSTRACTSarcocystis neurona is the primary agent for Equine Protozoal Myeloencephalitis (EPM), important neurological disease characterized by behavior or muscular changes, that impairs animal performance and husbandry. Sarcocystis cruzi is a pathogen related to myositis in cattle. Although related the life cycles of the parasites are distinct. S. neurona has opossums (Didelphis spp.) and S. cruzi, dogs as definitive hosts. However, S. neurona and S. cruzi may undergo cross-reactivity in serological ...
Tópico(s): Rabies epidemiology and control
2015 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Produção Nacional
Silvana Bastos Cogo, Taís Foletto Bevilaqua, Larissa Venturini, Fernanda Luisa Buboltz, Laís Mara Caetano da Silva, Márcio Rossato Badke, Elisabeta Albertina Nietsche, Tiérle Kosloski Ramos, Andrei Pompeu Antunes, Graciela Dutra Sehnem,
Objetivo: Caracterizar o perfil dos atendimentos de um serviço móvel de urgência e emergência de uma Universidade Federal do interior do Estado do Rio Grande do Sul. Métodos: Estudo quantitativo, descritivo, retrospectivo, que utilizou-se de dados secundários, coletados de fichas de atendimento no período de maio de 2017 a abril de 2018. Os dados foram digitados em planilha no Excel e analisados por meio do software Statistica 13.3. Resultados: A população atendida foi predominantemente de estudantes ...
Tópico(s): Health, Nursing, Elderly Care
2020 - Revista Eletronica Acervo Saude | Revista Eletrônica Acervo Saúde
Produção Nacional
Revisado por pares
João Luiz Guilherme Neto, Lucas Gabriel Rodrigues Venturini, Ayda Henriques Schneider, Thaise Mayumi Taira, Letícia Fernanda Duffles Rodrigues, Flávio P. Veras, Sicília Rezende Oliveira, Tarcı́lia Aparecida Silva, Fernando Q. Cunha, Sandra Yasuyo Fukada,
Introduction Neutrophil Extracellular Traps (NETs) have been described as structures composed of DNA and proteins, such as elastase and myeloperoxidase, which are able to kill bacteria extracellularly. The aim of the present study was to evaluate the role of NETs in bone resorption observed in pulp infection-induced apical periodontitis in mice. Methods Apical periodontitis was experimentally induced by exposing the dental pulp of the mandibular first molar of mice to the oral microenvironment. The ...
Tópico(s): S100 Proteins and Annexins
2023 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
James Venturini, Thais Fernanda de Campos Fraga‐Silva, Camila Martins Marchetti, Luiza Ayumi Nishiyama Mimura, Bruno José Conti, Márjorie de Assis Golim, Rinaldo Pôncio Mendes, Maria Sueli Parreira de Arruda,
Bloodstream infections caused by Candida species are responsible for high morbidity and mortality, and diabetes mellitus (DM) is an important underlying disease in candidemia episodes. Although DM patients show an enhanced proinflammatory profile, they are highly susceptible to mycobacterial and mycotic infections. Attempting to understand this paradox, we investigated if imbalanced macrophage and dendritic cell (DC) activations could be associated to high incidence and/or severity of Candida albicans ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2016 - Taylor & Francis | Immunological Investigations
Produção Nacional
Revisado por pares
Diogo A. Gálico, Marcelo G. Lahoud, Marian Rosaly Davolos, Regina C. G. Frem, Thais Fernanda de Campos Fraga‐Silva, James Venturini, Maria Sueli Parreira de Arruda, Gilbert Bannach,
Solid-state compounds of the general formulae [ML3] (M = Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Y; L = ketoprofen) were synthesized and characterized using infrared, diffuse reflectance and luminescence spectroscopies. IR data suggested that the carboxylate group in ketoprofen is coordinated to the metals as a bidentate ligand. The triplet state energy level was determined using the Gd3 + complex, which exhibited a ketoprofen blue luminescence when excited in the UV region. The compound containing Tb3 + ion was ...
Tópico(s): Magnetism in coordination complexes
2014 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
Fernanda Dias de Moraes, Francine Perri Venturini, Lucas Ribeiro Xavier Cortella, Priscila Adriana Rossi, Gilberto Moraes,
Pyrethroids are insecticides widely used in agriculture to control ectoparasites and biological vectors. They can reach the water bodies by leaching and or runoff. Fishes are highly sensitive to pyrethroids and the nervous system sensibility and the deficient drug metabolism are the clues but the toxicity mechanisms are yet unclear. The acute toxicity assays allow evaluating the potential, environmental risks of specific pesticides. Type II pyrethroids are becoming widely used and there is no law ...
Tópico(s): Pesticide and Herbicide Environmental Studies
2013 - | Ecotoxicology and Environmental contamination
Produção Nacional
Revisado por pares
G. L. Perpétuo, Gilberto Orivaldo Chierice, Laura Teófilo Ferreira, Thais Fernanda de Campos Fraga‐Silva, James Venturini, Maria Sueli Parreira de Arruda, Gilbert Bannach, Ricardo A. E. Castro,
A screening of ketoprofen cocrystal with nicotinamide as a coformer was performed using the Kofler contact method and mechanochemistry. The crystallization of KET (with cocrystal formation) can occur during the heating process. However, although it is thermodynamically favorable, it was found that the kinetic reactions were slow, since the KET crystallization took about 30 days. The compounds obtained were analysed by differential scanning calorimetry (DSC), polarized light thermomicroscopy (PLTM), ...
Tópico(s): Crystallization and Solubility Studies
2017 - Elsevier BV | Thermochimica Acta
Produção Nacional
Revisado por pares
Fernanda Dias de Moraes, Francine Perri Venturini, Priscila Adriana Rossi, Ive Marchioni Avilez, Naiara Elisabete da Silva de Souza, Gilberto Moraes,
Tópico(s): Aquaculture Nutrition and Growth
2018 - Springer Science+Business Media | Ecotoxicology
Produção Nacional
Revisado por pares
James Venturini, Anuska Marcelino Alvares-Saraiva, Marcela Rodrigues de Camargo, Camila Martins Marchetti, Thais Fernanda de Campos Fraga‐Silva, Ana Carolina Luchini, Maria Sueli Parreira de Arruda,
Recognizing the invasive potential of the dermatophytes and understanding the mechanisms involved in this process will help with disease diagnosis and with developing an appropriate treatment plan. In this report, we present the histopathological, microbiological and immunological features of a model of invasive dermatophytosis that is induced by subcutaneous infection of Trichophyton mentagrophytes in healthy adult Swiss mice. Using this model, we observed that the fungus rapidly spreads to the ...
Tópico(s): Plant Pathogens and Fungal Diseases
2012 - Elsevier BV | Microbes and Infection