Produção Nacional
Revisado por pares
Juan Pablo Arab, Juan Pablo Roblero, José Altamirano, Fernando Bessone, Roberta Chaves Araújo, Fatima Higuera‐de la Tijera, Juan Carlos Restrepo, Aldo Torre, Álvaro Urzúa, Douglas A. Simonetto, Juan G. Abraldeṣ, Nahúm Méndez‐Sánchez, F. Contreras, Michael R. Lucey, Vijay H. Shah, Helena Cortez‐Pinto, Ramón Bataller,
Alcohol-related liver disease (ALD) is a major cause of advanced chronic liver disease in Latin-America, although data on prevalence is limited. Public health policies aimed at reducing the alarming prevalence of alcohol use disorder in Latin-America should be implemented. ALD comprises a clinical-pathological spectrum that ranges from steatosis, steatohepatitis to advanced forms such as alcoholic hepatitis (AH), cirrhosis and hepatocellular carcinoma. Besides genetic factors, the amount of alcohol ...
Tópico(s): Liver Disease and Transplantation
2019 - Elsevier BV | Annals of Hepatology
J. Manuel Ledo, Henoc Flores, J. Manuel Solano-Altamirano, Fernando Ramos, Julio M. Hernández‐Pérez, E. Adriana Camarillo, Brenda Rabell, M. Patricia Amador,
We determined the standard molar enthalpies of formation in gas-phase, at T = 298.15 K, of the methyl 2-, 3-, and 4-hydroxybenzoates, through static bomb combustion calorimetry and thermogravimetry. The enthalpies of formation in gas phase were derived from experimental combustion energies and phase-change enthalpies. In addition, we calculated the enthalpies of formation in the gas-phase with the Gaussian G4 composite method combined with atomization reactions and a Boltzmann weighted average to ...
Tópico(s): Thermal and Kinetic Analysis
2018 - Elsevier BV | The Journal of Chemical Thermodynamics
Ana María Vega-Letter, Mónica Kurte, Catalina Fernández-O’Ryan, Melanie Gauthier-Abeliuk, Patricia Fuenzalida, Ivón Moya-Uribe, Claudia Altamirano, Fernando Figueroa, Carlos E. Irarrázabal, Flavio Carrión,
Recently, it has been observed that mesenchymal stem cells (MSCs) can modulate their immunoregulatory properties depending on the specific in-vitro activation of different Toll-like receptors (TLR), such as TLR3 and TLR4. In the present study, we evaluated the effect of polyinosinic:polycytidylic acid (poly(I:C)) and lipopolysaccharide (LPS) pretreatment on the immunological capacity of MSCs in vitro and in vivo.C57BL/6 bone marrow-derived MSCs were pretreated with poly(I:C) and LPS for 1 hour and their ...
Tópico(s): Immune Response and Inflammation
2016 - BioMed Central | Stem Cell Research & Therapy
Mario Suwalsky, Małgorzata Jemioła‐Rzemińska, Mariella Altamirano, Fernando Pardo‐Manuel de Villena, Nathan Dukes, Kazimierz Strzałka,
Aimed to better understand the molecular mechanisms of its interactions with cell membranes, human erythrocyte and molecular models of the red cell membrane were utilized. The latter consisted of bilayers of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE), representative of phospholipid classes located in the outer and inner monolayers of the human erythrocyte membrane, respectively. The capacity of amantadine to perturb the bilayer structures of DMPC and DMPE ...
Tópico(s): Neonatal Health and Biochemistry
2015 - Elsevier BV | Biophysical Chemistry
Roberto Rivera‐Luna, Cecilia Correa‐González, Eduardo Altamirano‐Alvarez, Fernando Sánchez‐Zubieta, Rocío Cárdenas‐Cardós, Gabriela Escamilla‐Asian, Alberto Olaya‐Vargas, Aurora Bautista‐Marquez, Manuel Aguilar‐Romo,
Prior to 2005, 51% of children in Mexico diagnosed with cancer received no standardized optimal multidisciplinary medical care. A government-subsidized national cancer treatment program was therefore created for these patients and a National Cooperative Childhood Cancer Treatment Group was consequently formed for these patients. Pediatric patients with a proven diagnosis of leukemia, lymphoma or solid tumor and who were registered in the Popular Medical Insurance (PMI) program from January 2007 to ...
Tópico(s): Child and Adolescent Health
2012 - Wiley | International Journal of Cancer
Hilda Flores‐Olvera, Roberto Lindig Cisneros,
BECAUSE OF THE IMPORTANCE OF THE LIST OF PLANT SPECIES FOR REPOPULATING THE FORESTS OF THE MEXICAN REPUBLIC, FIRST PUBLISHED BY ALTAMIRANO AND RAMÍREZ 111 YEARS AGO, AND THE DIFFICULTY TO ACCESS IT, A LIST IS PRESENTED CONSIDERING CURRENT TRENDS IN ECOLOGICAL RESTORATION, AND CORRECTED SCIENTIFIC NAMES WERE ADDED TO FACILITATE ITS USE. TO IMPROVE THE UTILITY OF THE LIST SOME INFORMATION SUCH LIKE IF THE SPECIES ARE NATIVE OR INTRODUCED, THEIR USES AND PROPAGATION METHODS IS PROVIDED. THE AUTHORS ...
Tópico(s): Botany and Geology in Latin America and Caribbean
2005 - National Autonomous University of Mexico | Revista Mexicana de Biodiversidad
Fabián S. Mederos-Nieto, Ignacio Elizalde, Raúl Hernández‐Altamirano, Fernando Trejo‐Zárraga, Violeta Y. Mena‐Cervantes, Edgar Ramírez-Jiménez, Daniela E. Vallarta-Cardona,
Abstract Some of the main problems during vegetable oil hydrotreating are the high heat of reaction released, the huge quantity of expensive hydrogen required, and the high corrosion rates in the equipment. Some insights into the advantages and disadvantages of processing raw vegetable oils or their respective fatty acid methyl esters are given. The ASPEN Plus process simulator was used for the simulation of a hydrotreating process, with two different feedstocks coming from the same plant: raw castor ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2018 - Wiley | Chemical Engineering & Technology
Fernando Gordillo Altamirano, Xenia Kostoulias, Dinesh Subedi, Denis V. Korneev, Anton Y. Peleg, Jeremy J. Barr,
Clinical phage therapy is often delivered alongside antibiotics. However, the phenomenon of phage-antibiotic synergy has been mostly studied in vitro. Here, we assessed the in vivo bactericidal effect of a phage-antibiotic combination on Acinetobacter baumannii AB900 using phage øFG02, which binds to capsular polysaccharides and leads to antimicrobial resensitisation in vitro.We performed a two-stage preclinical study using a murine model of severe A. baumannii AB900 bacteraemia. In the first stage, ...
Tópico(s): Antibiotic Resistance in Bacteria
2022 - Elsevier BV | EBioMedicine
Fernando Gordillo Altamirano, Jeremy J. Barr,
Lysogenic phages can integrate into their bacterial host's genome, potentially transferring any genetic information they possess including virulence or resistance genes, and are therefore routinely excluded from therapeutic applications. Lysogenic behavior is typically seen in phages that create turbid plaques or possess subpar bactericidal activity; yet, these are not definitive indicators. As a result, the presence of integrase genes is often used as a hallmark for lysogenic behavior; however, ...
Tópico(s): Microbial infections and disease research
2021 - American Academy of Arts and Sciences | BIO-PROTOCOL
Fernando Gordillo Altamirano, John H. Forsyth, Ruzeen Patwa, Xenia Kostoulias, Michael Trim, Dinesh Subedi, Stuart K. Archer, Faye C. Morris, Cody Oliveira, Luisa Kielty, Denis V. Korneev, Moira K. O’Bryan, Trevor Lithgow, Anton Y. Peleg, Jeremy J. Barr,
We characterized two bacteriophages, ΦFG02 and ΦCO01, against clinical isolates of Acinetobacter baumannii and established that the bacterial capsule is the receptor for these phages. Phage-resistant mutants harboured loss-of-function mutations in genes responsible for capsule biosynthesis, resulting in capsule loss and disruption of phage adsorption. The phage-resistant strains were resensitized to human complement, beta-lactam antibiotics and alternative phages and exhibited diminished fitness ...
Tópico(s): Microbial infections and disease research
2021 - Nature Portfolio | Nature Microbiology
Xiaoqing Wang, Belinda Loh, Fernando Gordillo Altamirano, Yunsong Yu, Xiaoting Hua, Sebastián Leptihn,
Multidrug-resistant bacterial infections are becoming increasingly common, with only few last-resort antibiotics such as colistin available for clinical therapy. An alternative therapeutic strategy gaining momentum is phage therapy, which has the advantage of not being affected by bacterial resistance to antibiotics. However, a major challenge in phage therapy is the rapid emergence of phage-resistant bacteria. In this work, our main aim was to understand the mechanisms of phage-resistance used ...
Tópico(s): Microbial infections and disease research
2021 - Taylor & Francis | Emerging Microbes & Infections
Fernando Gordillo Altamirano, Jeremy J. Barr,
Phage therapy, the clinical use of viruses that kill bacteria, is a promising strategy in the fight against antimicrobial resistance. Before administration, phages undergo a careful examination of their safety and interactions with target bacteria. This characterization seldom includes identifying the receptor on the bacterial surface involved in phage adsorption. In this perspective article, we propose that understanding the function and location of these phage receptors can open the door to improved ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2020 - Elsevier BV | Current Opinion in Biotechnology
Fernando Gordillo Altamirano, Jeremy J. Barr,
Antibiotic resistance is arguably the biggest current threat to global health. An increasing number of infections are becoming harder or almost impossible to treat, carrying high morbidity, mortality, and financial cost. The therapeutic use of bacteriophages, viruses that infect and kill bacteria, is well suited to be part of the multidimensional strategies to combat antibiotic resistance. Although phage therapy was first implemented almost a century ago, it was brought to a standstill after the ...
Tópico(s): Viral gastroenteritis research and epidemiology
2019 - American Society for Microbiology | Clinical Microbiology Reviews
Walter Ramiro Jiménez Silva, Janeth Larrea-Altamirano, Mario Fernando Navarrete Fonseca, Edisson Castro-Ayala,
La preocupacion de las Universidades por generar emprendimientos innovadores en la actualidad es una tarea complicada, por ello es necesario partir de un escenario de consolidacion de competencias cognitivas incentivar el emprendimiento. El proposito de la investigacion fue caracterizar los emprendimientos innovadores, a partir de las competencias cognitivas fomentadas en los estudiantes de la Facultad de Ciencias Administrativas de la Universidad Tecnica de Ambato, Ecuador, la cual cuenta con 14222 ...
Tópico(s): Diverse Applied Research Studies
2019 - University of Zulia | Revista Venezolana de Gerencia
Produção Nacional
Revisado por pares
Carlos Almeida, Tânia Marina Palhano Zanela, Clodoaldo Machado, Juan Antônio Altamirano Flores, Luiz Fernando Scheibe, Nicholas P. Hankins, Nito Ângelo Debacher,
An aluminosilicate waste (AW) was investigated as adsorbent for methylene blue (MB) dye. AW was characterized by petrography, X-ray diffractometry, X-ray fluorescence, scanning electron microscopy, thermogravimetry and zeta potential measurements. It was found that AW contains kaolinite, and other minor components such as quartz, muscovite, smectite, siderite, pyrite and organic compounds. The chemical composition of AW is mainly SiO2 (49%) and Al2O3 (23%) and it has negative superficial charge above ...
Tópico(s): Electrochemical Analysis and Applications
2016 - Pergamon Press | Water Science & Technology
Edgar Abarca‐Rojano, Saé Muñiz‐Hernández, María Maximina Bertha Moreno‐Altamirano, Ricardo Mondragón‐Flores, Fernando Enrı́quez-Rincón, Francisco Javier Sánchez‐García,
As part of the innate immune response NK cells destroy infected, transformed, or otherwise stressed cells within hours of activation. In contrast, CD4+ T lymphocytes require a sustained increase in their metabolism in order to cope with the biogenesis of cell components, in a process of proliferation and differentiation into effector cells. Recently, mitochondria have been implied in T lymphocyte immune synapse function but little is known on the role of mitochondria in the NK cell interaction with ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2008 - Elsevier BV | Immunology Letters
Fabián S. Mederos-Nieto, Ignacio Elizalde, Fernando Trejo‐Zárraga, Raúl Hernández‐Altamirano, Fernando Alonso,
Tópico(s): Biodiesel Production and Applications
2020 - Springer Science+Business Media | Reaction Kinetics Mechanisms and Catalysis
Antonio Enrique Salas-Reyes, Gerardo Altamirano-Guerrero, Jóse Fernando Flores Álvarez, F. Chávez, Armando Salinas‐Rodríguez, I.A. Figueroa, Gabriel Lara Rodriguez,
As a high-performance material, advanced TWIP steels have recently received considerable attention, particularly promising to form parts of complex geometry due to the superior mechanical properties. In the present research work, the study of the corrosion resistance of an experimental advanced TWIP steel was carried out with the purpose of establishing the relationship between its chemical composition and processing condition. The aforementioned was achieved by evaluating the effect of boron microaddition ...
Tópico(s): Corrosion Behavior and Inhibition
2020 - Elsevier BV | Journal of Materials Research and Technology
Miguel A. Padilla, F. Altamirano, Fernando Arámbula Cosı́o, Jorge Márquez,
In this work is presented the development of a mechatronic interface for a surgery simulation system for training transurethral resection of the prostate (TURP). The interface emulates a real resectoscope and allows to perform the most important movements of the surgical tool during a TURP. The interface is able to work in conjunction with a virtual reality software with a deformable tissue model of the prostate, in order to simulate tissue resection and deformation. The current prototype has five ...
Tópico(s): Anatomy and Medical Technology
2007 - Institute of Electrical and Electronics Engineers | Conference proceedings
Fernando Gabriel Altamirano, Ivanna C. Castro-Pascual, Mariana L. Ferramola, Marina Luz Tula, Silvia M. Delgado, Ana Cecilia Anzulovich, María Gabriela Lacoste,
Tópico(s): Sodium Intake and Health
2021 - Springer Science+Business Media | Biogerontology
Roberto Rivera‐Luna, Jaime Shalkow‐Klincovstein, Liliana Velasco‐Hidalgo, Rocío Cárdenas‐Cardós, Marta Zapata‐Tarrés, Alberto Olaya‐Vargas, Marco Rodrigo Aguilar-Ortiz, Eduardo Altamirano‐Alvarez, Cecilia Correa‐González, Fernando Sánchez‐Zubieta, Francisco Pantoja-Guillén,
All the children registered at the National Council for the Prevention and Treatment of Childhood Cancer were analyzed. The rationale for this Federal Government Council is to financially support the treatment of all children registered into this system. All patients are within a network of 55 public certified hospitals nationwide.In the current study, data from 2007 to 2012 are presented for all patients (0-18 years) with a pathological diagnosis of leukemia, lymphoma and solid tumors. The parameters ...
Tópico(s): Child and Adolescent Health
2014 - BioMed Central | BMC Cancer
Norma A. Valdez‐Cruz, Enrique García‐Hernández, Clara Espitia, Laura Cobos-Marín, Claudia Altamirano, Carlos G. Bando-Campos, Luis Fernando Cofas‐Vargas, Enrique Wenceslao Coronado-Aceves, Ricardo A. González-Hernández, Pablo Hernández-Peralta, Daniel Juárez-López, Paola Andrea Ortega-Portilla, Sara Restrepo-Pineda, Patricio Zelada, Mauricio A. Trujillo‐Roldán,
Abstract SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far. Based on the urgent need for therapeutic and prophylactic strategies, the identification and characterization of antibodies has been accelerated, since they have been fundamental in treating other viral diseases. Here, we summarized in an integrative manner the present understanding of the immune response and ...
Tópico(s): SARS-CoV-2 detection and testing
2021 - BioMed Central | Microbial Cell Factories
Paula López-Arce, Héctor Altamirano, James Berry, Dimitrios Rovas, Fernando Sarce, S. Hodgson,
Abstract The occurrence of surface condensation and mould can lead to concerns of poor indoor air quality and adverse health implications of occupants. Remedial actions require identification of the root causes, but this can be challenging even for experts. The focus of the research is the development of a diagnostic tool that helps to streamline root cause analysis. The diagnostic method comprises a protocol with guidelines for installation of sensors, easy data collection, and a set of calculations ...
Tópico(s): Conservation Techniques and Studies
2020 - Springer Science+Business Media | Building Simulation
Tomás A. Altamirano, José Tomás Ibarra, Fernando Novoa, Alejandra Vermehren, Kathy Martin, Cristián Bonacic,
Tree cavities can provide critical roosting sites for cavity-using vertebrates.These sites can directly affect productivity and survival of bats.Histiotus magellanicus, one of the bat species with the southernmost distribution in the world, is suspected to use tree cavities, under bark, caves and human buildings for roosting.We document the first records of this bat roosting in tree cavities created by both cavity-facilitators (i.e., excavators) and tree-decay processes on standing dead and large ...
Tópico(s): Amphibian and Reptile Biology
2017 - Austral University of Chile | Bosque (Valdivia)
Javier Gil‐Humanes, Fernando Pistón, Rossana Altamirano‐Fortoul, Ana Real, Isabel Comino, Carolina Sousa, Cristina M. Rosell, Francisco Barro,
Wheat flour cannot be tolerated by those who suffer allergies to gluten. Human pathologies associated with grain proteins have increased worldwide in recent years, and the only effective treatment available is a lifelong gluten-free diet, which is complicated to follow and detrimental to gut health. This manuscript describes the development of wheat bread potentially suitable for celiac patients and other gluten-intolerant individuals. We have made bread using wheat flour with very low content of ...
Tópico(s): Microscopic Colitis
2014 - Public Library of Science | PLoS ONE
Fabián S. Mederos-Nieto, Adid O. Santoyo-López, Raúl Hernández‐Altamirano, Violeta Y. Mena‐Cervantes, Fernando Trejo‐Zárraga, Guillermo Centeno-Nolasco, Edgar Ramírez-Jiménez,
In recent years, many studies have been published on the hydrotreating of non-edible vegetable oils, however, a limited number of them deal with the hydroprocessing of their corresponding fatty acid methyl esters for the productions of renewable fuels. In this study is outlined the production of renewable fuels from castor bean seeds (Ricinus communis L.) in two stages, the first one is to obtain the respective castor oil methyl esters by reactive extraction and the second one is to apply the hydrotreating ...
Tópico(s): Catalysis for Biomass Conversion
2020 - Elsevier BV | Fuel
Henoc Flores, J. Manuel Ledo, E. Adriana Camarillo, J. Manuel Solano-Altamirano, Julio M. Hernández‐Pérez, Fernando Ramos, Brenda Rabell,
In this work, we determine, both experimentally and computationally, structural and thermochemical properties of the methyl 2- and 4-methoxybenzoates. Combustion and vaporization enthalpies of these compounds were obtained experimentally through combustion calorimetry and thermogravimetry. From these properties, their standard molar enthalpies of formation in the gas phase, at T = 298.15 K, were also determined. In addition, we computed gas-phase enthalpies of formation of methyl 2-, 3-, and 4-methoxybenzoates ...
Tópico(s): thermodynamics and calorimetric analyses
2019 - American Chemical Society | Journal of Chemical & Engineering Data
Fernando Gordillo Altamirano, María José Fierro Torres, Nelson Salas, María Cristina Cervantes Vélez,
Identificar los principales determinantes de la calidad de vida relacionada con la salud (CVRS) de pacientes con dolor neuropático oncológico en un hospital de tercer nivel de atención. Estudio transversal analítico. En una muestra de 237 pacientes con criterios de dolor neuropático de origen oncológico, se midieron variables clínico-demográficas: tipo de cáncer, estadio, tiempo de diagnóstico, intensidad del dolor, funcionalidad física con la escala PPS, y ansiedad y depresión con la escala HADS. ...
Tópico(s): Management of metastatic bone disease
2016 - Elsevier BV | Revista Colombiana de Psiquiatría
Produção Nacional
Ayelén L. Gómez, Melisa B. Delconte, Gabriela A. Altamirano, Lucía Vigezzi, Verónica L. Bosquiazzo, Luı́s Fernando Barbisan, Jorge G. Ramos, Enrique H. Luque, Mónica Muñoz‐de‐Toro, Laura Kass,
The development of the mammary gland is a hormone-regulated event. Several factors can dysregulate its growth and make the gland more susceptible to cellular transformation. Among these factors, perinatal exposure to xenoestrogens and hormone replacement therapy has been associated with increased risk of developing breast cancer. Here, we assessed the effects induced by estrogen replacement therapy (ERT) in ovariectomized (OVX) middle-aged rats and whether perinatal exposure to diethylstilbestrol ( ...
Tópico(s): Cancer Risks and Factors
2017 - Springer Science+Business Media | Hormones and Cancer
Fernando de Andrés, Catalina Altamirano-Tinoco, Ronald Ramírez‐Roa, Carlos F Montes-Mondragón, Pedro Dorado, Eva Peñas‐Lledó, Adrián LLerena,
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2020 - Springer Nature | The Pharmacogenomics Journal