Marina M.S. Cabral-Pinto, M.M.V.G. Silva, Eduardo Ferreira da Silva, Pedro Dinis, Fernando Rocha,
The understanding of rock-soil geochemical fluxes provides an important tool for evaluating natural environmental risk. In this research we compare the geochemical composition of soils (n = 249) collected on Santiago Island (Cape Verde) with their parent rocks (n = 96). Basalt and basanites units and overlying soils are relatively rich in Co, Sc, Mg, Ca, Fe, V, Ti, Ni, Cr, and Cu, whilst phonolitic-trachytic units and overlying soils are relatively rich in Zn, P, Sr, Mn, Ba, La, As, Th and Pb. An enrichment ...
Tópico(s): Heavy Metal Exposure and Toxicity
2017 - Elsevier BV | Journal of Geochemical Exploration
P. Pedrosa, Rui Dinis, Fernando D. Nunes,
Broadband broadcast and multicast wireless systems usually employ OFDM modulations (Orthogonal Frequency Division Multiplexing) combined with non-uniform hierarchical constellations. However, these schemes are very prone to nonlinear distortion effects and have high carrier synchronization requirements. SC-FDE (Single-Carrier with Frequency-Domain Equalization) is an attractive alternative for OFDM, especially when an efficient power amplification is intended. In this paper we consider the use of ...
Tópico(s): Wireless Communication Networks Research
2010 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Broadcasting
Fernando Magro, Mário Dinis‐Ribeiro, Fernando M Ara jo, Pedro A. Pereira, Manuela C Fraga, L. M. Cunha‐Ribeiro, Ant nio Tom -Ribeiro,
Introduction A hypercoagulable state has been recognized in patients with inflammatory bowel disease. Objective The aim of this study was to determine the frequency of single and combined thrombophilic abnormalities in patients from northern Portugal with Crohn's disease or ulcerative colitis, without a history of thrombosis. Methods A cross-sectional study involving 116 patients (42 with ulcerative colitis, 74 with Crohn's disease), and 141 randomly chosen asymptomatic blood donors was carried out. ...
Tópico(s): Inflammatory Bowel Disease
2003 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Produção Nacional
Revisado por pares
Renato Sakai Cid, Vinicius Roveri, Diogo Guedes Vidal, Maria Alzira Pimenta Dinis, Fernando Sanzi Cortez, Flávia Rigos Salgueiro, Walber Toma, Augusto César, Luciana Lopes Guimarães,
Antiretrovirals (ARVs) have been detected in aquatic ecosystems throughout the world; however, studies focused on assessing their ecotoxicological effects on marine aquatic organisms are still rare. In the present study, the predicted environmental concentration (PEC) of 13 ARVs was estimated for surface seawater from Santos Bay, Brazil, according to the European Medicines Agency (EMEA) guidelines. The results indicated that all ARVs need to be assessed for their ecological effects, considering that ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2021 - Multidisciplinary Digital Publishing Institute | Resources
Fernando Magro, Elaine F. F. da Cunha, Fernando Araújo, Elsa Meireles, Pedro L. Valls Pereira, Mário Dinis‐Ribeiro, Fernando Tavarela Veloso, Rui Medeiros, Patrício Soares‐da‐Silva,
Tópico(s): Microscopic Colitis
2006 - Springer Science+Business Media | Digestive Diseases and Sciences
Rafael Lomba‐Viana, Mário Dinis‐Ribeiro, Fernando Fonseca, Anabela Silva Vieira, María José Bento, Helena Lomba-Viana,
To estimate the adherence of Western individuals to serum pepsinogen (PG) test and its accuracy in the detection of gastric cancer followed by upper gastrointestinal endoscopy.Individuals from the northern region of Portugal, aged between 40 and 79 years, were invited to participate in a blood collection for the determination of serum PG values by ELISA method (Biohit kits). Participants were classified into two groups: positive (PG I ≤70 ng/ml and PG I/ PGII ≤3) and negative (all others). All participants ...
Tópico(s): Diet, Metabolism, and Disease
2011 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Ricardo Jorge Dinis‐Oliveira, Fernando Remião, Helena Carmo, José Alberto Duarte, Amparo Sánchez Navarro, Maria de Lourdes Bastos, Félix Carvalho,
Parkinson's disease (PD) is a multifactorial chronic progressive neurodegenerative disease influenced by age, and by genetic and environmental factors. The role of genetic predisposition in PD has been increasingly acknowledged and a number of relevant genes have been identified (e.g., genes encoding α-synuclein, parkin, and dardarin), while the search for environmental factors that influence the pathogenesis of PD has only recently begun to escalate. In recent years, the investigation on paraquat ( ...
Tópico(s): Pesticide Exposure and Toxicity
2006 - Elsevier BV | NeuroToxicology
Ricardo Jorge Dinis‐Oliveira, Fernando Remião, José Alberto Duarte, Rita Ferreira, Amparo Sánchez Navarro, Maria de Lourdes Bastos, Félix Carvalho,
Tópico(s): Poisoning and overdose treatments
2006 - Elsevier BV | Free Radical Biology and Medicine
Hélder Pereira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Vasco da Gama Ribeiro, Vítor Brandão, Dinis Martins, Fernando Matias, Francisco Pereira‐Machado, José Baptista, Pedro Farto e Abreu, Ricardo Santos de Oliveira, António Drummond, Henrique Carvalho, João Calisto, João Carlos Silva, João Pipa, Jorge Marques, Paulino Sousa, Renato Fernandes, Rui Cruz Ferreira, Sousa Ramos, Eduardo Infante de Oliveira, Manuel Almeida,
The aim of the present paper was to report trends in coronary angioplasty for the treatment of ST-elevation myocardial infarction (STEMI) in Portugal.Prospective multicenter data from the Portuguese National Registry of Interventional Cardiology (RNCI) and official data from the Directorate-General for Health (DGS) were studied to analyze percutaneous coronary intervention (PCI) procedures for STEMI from 2002 to 2013.In 2013, 3524 primary percutaneous coronary intervention (p-PCI) procedures were performed ( ...
Tópico(s): Acute Myocardial Infarction Research
2016 - Elsevier BV | Revista Portuguesa de Cardiologia
Cláudia Silva, José Magano, А. А. Москаленко, Teresa Nogueira, Maria Alzira Pimenta Dinis, Hélder Fernando Pedrosa e Sousa,
Companies need to develop more sustainable management models to support a strategy focused on the environment and society, preventing the sole ambition to maximize economic profits. Several specific tools and frameworks have been developed for the implementation of sustainability management. However, the isolated adoption of new management practices could increase bureaucracy and constrain the development of an effective and systematic sustainability strategy. Based on the development of four case ...
Tópico(s): Technology Assessment and Management
2020 - Multidisciplinary Digital Publishing Institute | Sustainability
Maria M. A. S. Maia, Marisa Dinis-Almeida, Fernando Martinho,
Two of the main problems encountered in flexible pavements are the stripping of coarse aggregates and the formation of rut depth due to increases in the volume of road traffic and heavy vehicle loads, especially in areas where speeds are low. The existence of rut depth also affects the comfort and safety of road users due to the water accumulation on the pavement surface and reducing tire/pavement friction, which can lead to hydroplaning phenomena. In this research, it was proven that the use of ...
Tópico(s): Transport Systems and Technology
2021 - Multidisciplinary Digital Publishing Institute | Materials
Maria Alzira Pimenta Dinis, Hélder Fernando Pedrosa e Sousa, Andreia de Moura, Lilian Monteiro Ferrari Viterbo, Ricardo J. Pinto,
The etiology of diseases is multifactorial, involving genetic, environmental, and lifestyle-related behaviors. Considering the pathway that involves behavioral processes, a huge body of empirical evidence has shown that some healthy behaviors such as non-smoking, any or moderate alcohol consumption, a healthy diet, (e.g., fruit and vegetable intake), and physical activity, decrease the risk of disease and mortality. This study aimed to explore the potential mediating effect of combined health behaviors ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Cesar Augusto Masella, Vitor Ferreira Pinho, Afonso Dinis Costa Passos, Fernando Antônio Campelo Spencer Netto, Sandro Rizoli, Sandro Scarpelini,
Examination of the epidemiology and timing of trauma deaths has been deemed a useful method to evaluate the quality of trauma care.The purpose of this study was to evaluate the quality of trauma care in a regional trauma system and in a university hospital in Brazil by comparing the timing of deaths in the studied prehospital and in-hospital settings to those published for trauma systems in other areas.We analyzed the National Health Minister's System of Deaths Information for the prehospital mortality ...
Tópico(s): Emergency and Acute Care Studies
2008 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Produção Nacional
Revisado por pares
Lívia Pimenta Bonifácio, Ana Paula Sulino Pereira, Daniel Cardoso de Almeida e Araújo, Viviane da Mata Pasti Balbão, Benedito Antônio Lopes da Fonseca, Afonso Dinis Costa Passos, Fernando Bellissimo‐Rodrigues,
With the large number of individuals infected and recovered from Covid-19, there is intense discussion about the quality and duration of the immunity elicited by SARS-CoV-2 infection, including the possibility of disease recurrence. Here we report a case with strong clinical, epidemiological and laboratorial evidence of, not only reinfection by SARS-CoV-2, but also clinical recurrence of Covid-19.
Tópico(s): SARS-CoV-2 detection and testing
2020 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
P. Pedrosa, Rui Dinis, Fernando D. Nunes, António Rodrigues,
In this study the authors propose a novel joint detection and phase noise estimation scheme suited for severely time-dispersive channels. The authors consider single-carrier modulations combined with frequency domain equalisation schemes where the wireless transmission is impaired with phase noise. An iterative frequency-domain equaliser is assumed on the receiver side and the phase noise is estimated and compensated for after the equalisation step and within each iteration of the equaliser. In ...
Tópico(s): Cellular Automata and Applications
2015 - Institution of Engineering and Technology | IET Communications
Produção Nacional
Revisado por pares
Afonso Dinis Costa Passos, José Fernando de Castro Figueiredo, Ana de Lourdes Candolo Martinelli, Márcia G. Villanova, Margarida Maria Pásseri do Nascimento, Marie Secaf,
This study was performed with the purpose of testing the hypothesis that the high prevalence of hepatitis C among former athletes is associated with their past use of injectable stimulants. The study involved the participation of 208 former professional and amateur soccer and basketball players from the region of Ribeirão Preto, Brazil, who answered a questionnaire regarding their exposure to risk factors, including the use of injectable stimulants in the time they were engaged in sporting activities. ...
Tópico(s): Hepatitis B Virus Studies
2008 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Afonso Dinis Costa Passos, José Fernando de Castro Figueiredo, Ana de Lourdes Candolo Martinelli, Márcia G. Villanova, Margarida P. Nascimento, Ana Maria Coimbra Gaspar, Clara Fumiko Tachibana Yoshida,
OBJECTIVE: To estimate the prevalence of hepatitis B markers and to study the risk factors for this disease among female sex workers in the city of Ribeirão Preto, Brazil. METHODS: A questionnaire was given to 449 female sex workers in order to obtain information about demographic, socioeconomic and behavioral variables. Blood samples were collected and analyzed by immunoenzymatic techniques for detection of HBsAg, anti-HBs, anti-HBc and anti-HCV markers. RESULTS: The mean age of participants was ...
Tópico(s): Hepatitis C virus research
2007 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Maria Rita de Cássia Costa Monteiro, Margarida Maria Pásseri do Nascimento, Afonso Dinis Costa Passos, José Fernando de Castro Figueiredo,
O objetivo desta pesquisa foi estudar a prevalência de infecção pelo virus da hepatite B em 406 portadores do virus da imunodeficiência humana, maiores de dezoito anos de idade, atendidos na rede pública de saúde da cidade de Belém, Pará, assim como analisar possíveis fatores de risco para a infecção. A prevalência global de infecção pelo virus da hepatite B foi de 51% (IC: 46,1 - 55,8), com 7,9% (IC: 5,3 - 10,5) para o HBsAg, 45,1% (IC: 40,3 - 49,9) para o anti-HBc e 32,3% (IC: 27,5 - 36,8) para o anti-HBs. ...
Tópico(s): Viral-associated cancers and disorders
2004 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Maria Rita de Cássia Costa Monteiro, Margarida Maria Pásseri do Nascimento, Afonso Dinis Costa Passos, José Fernando de Castro Figueiredo,
Este trabalho objetivou investigar a prevalência de infecção pelo vírus da hepatite C e identificar possíveis fatores de risco para sua transmissão, em 406 indivíduos portadores do vírus da imunodeficiência humana, maiores de dezoito anos de idade, atendidos na rede pública de saúde da cidade de Belém, Pará, situada na Amazônia brasileira. Os exames referentes ao anti-VHC foram realizados pelo método de Elisa e a pesquisa do VHC RNA através da reação de polimerase em cadeia. A prevalência de infecção, ...
Tópico(s): Liver Disease Diagnosis and Treatment
2004 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Afonso Dinis Costa Passos, José Fernando de Castro Figueiredo,
OBJETIVO: Caracterizar a população de profissionais do sexo em atividade em Ribeirão Preto, Brasil, segundo variáveis demográficas e socioeconômicas, e estudar os fatores de risco para doenças sexualmente transmissíveis nessa população. MÉTODOS: Foram visitados todos os locais de prática de prostituição identificados na cidade. Os participantes responderam um questionário que levantava informações sócio-demográficas e fatores de risco para doenças sexualmente transmissíveis. Foi responsável pelas ...
Tópico(s): HIV/AIDS Research and Interventions
2004 - Pan American Health Organization | Revista Panamericana de Salud Pública
Marco Dinis, Khaled Merabet, Fernando Martínez‐Freiría, Sebastian Steinfartz, Miguel Vences, James D. Burgon, Kathryn R. Elmer, David Donaire-González, Arlo Hinckley, Soumía Fahd, Ulrich Joger, Adnane Fawzi, Tahar Slimani, Guillermo Velo‐Antón,
North Africa is a climatically and topographically complex region with unique biotic assemblages resulting from the combination of multiple biogeographic realms. Here, we assess the role of climate in promoting intra-specific diversification in a Palearctic relict, the North African fire salamander, Salamandra algira, using a combination of phylogenetic and population genetic analyses, paleoclimatic modelling and niche overlap tests. We used mitochondrial DNA (Cyt-b), 9838 ddRADseq loci, and 14 microsatellite ...
Tópico(s): Amphibian and Reptile Biology
2018 - Elsevier BV | Molecular Phylogenetics and Evolution
Luís Félix, Maria Manuel Oliveira, Romeu A. Videira, Elisabete Maciel, Nuno Dinis Alves, Fernando M. Nunes, Anabela Alves, José M. Almeida, M. Rosário M. Domingues, Francisco Peixoto,
Gentamicin is an aminoglycoside antibiotic widely used to treat many types of bacterial infections. Although its properties, his clinical use is limited due to the occurrence of nephrotoxicity, which has been related to mitochondrial dysfunction. Carvedilol, an antihypertensive drug with strong antioxidant properties, has been tested in order to prevent gentamicin nephrotoxicity. This study aimed to test this hypothesis using a rat model of gentamicin-induced nephrotoxicity. Animals were treated ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2016 - Elsevier BV | Experimental and Toxicologic Pathology
Hélder Pereira, Daniel Caldeira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Vasco da Gama Ribeiro, Vítor Brandão, Dinis Martins, Fernando Matias, Francisco Pereira‐Machado, José Baptista, Pedro Farto e Abreu, Ricardo Santos de Oliveira, António Drummond, Henrique Carvalho, João Calisto, João Carlos Silva, João Pipa, Jorge Marques, Paulino Sousa, Renato Fernandes, Rui Cruz Ferreira, Sousa Ramos, Eduardo Infante de Oliveira, Manuel Almeida,
We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ‘real-world’ settings. We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006–2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). We assessed data for 9458 STEMI ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2018 - BioMed Central | BMC Cardiovascular Disorders
Ricardo Jorge Dinis‐Oliveira, Carla Sousa, Fernando Remião, José Alberto Duarte, Rita Ferreira, Amparo Sánchez Navarro, Maria de Lourdes Bastos, Félix Carvalho,
The nonselective contact herbicide, paraquat (PQ), is a strong pneumotoxicant, especially due to its accumulation in the lung through a polyamine uptake system and to its capacity to induce redox cycling, leading to oxidative stress-related damage. In the present study, we aimed to investigate the occurrence of apoptotic events in the lungs of male Wistar rats, 24, 48, and 96 h after PQ exposure (25 mg/kg ip) as well as the putative healing effects provided by sodium salicylate [(NaSAL), 200 mg/kg ip] ...
Tópico(s): Chemotherapy-induced organ toxicity mitigation
2007 - Elsevier BV | Free Radical Biology and Medicine
Ricardo Jorge Dinis‐Oliveira, Carla Sousa, Fernando Remião, José Alberto Duarte, Amparo Sánchez Navarro, Maria de Lourdes Bastos, Félix Carvalho,
Over the past decades, there have been numerous fatalities resulting from accidental or voluntary ingestion of the widely used herbicide paraquat dichloride (methyl viologen; PQ). Considering that the main target organ for PQ toxicity is the lung and involves the production of reactive oxygen and nitrogen species, inflammation, disseminated intravascular coagulation, and activation of transcriptional regulatory mechanisms, it may be hypothesized that an antidote against PQ poisonings should counteract ...
Tópico(s): Methemoglobinemia and Tumor Lysis Syndrome
2007 - Elsevier BV | Free Radical Biology and Medicine
David Mendes, Pedro Dinis Gaspar, Fernando Charrua-Santos, Helena V. G. Navas,
As the global market becomes increasingly competitive and demanding, companies face the challenge of responding swiftly and efficiently to customer needs. To maintain a competitive advantage, organisations must optimise the usage of their assets. This study focuses on the critical role of maintenance management and presents a novel, cost-effective, and easily applicable model that integrates Industry 4.0 (I4.0) and Total Productive Maintenance (TPM) principles to enhance production processes. The ...
Tópico(s): Quality and Supply Management
2023 - Multidisciplinary Digital Publishing Institute | Processes
Renan Zocca, Tânia M. Lima, Pedro Dinis Gaspar, Fernando Charrua-Santos,
Kaizen is one of the continuous improvement management tools encompassed by Lean Manufacturing. 5S methodology is a reorganization technique for the companies generally associated with Kaizen technique. It was specifically developed with the aim of transforming the environment of people's organizations and attitudes, resulting in improvement of employees' quality of life and the reduction of waste and costs, and aiming significant increases in productivity. Portuguese food industry is composed mainly ...
Tópico(s): Supply Chain Resilience and Risk Management
2018 - Springer Nature | Advances in intelligent systems and computing
Carmen Caeiro, Helena Canhão, Sofia Guerra-Paiva, Luís Antunes Gomes, Rita Fernandes, Ana Maria Rodrigues, Rute Dinis de Sousa, Fernando Pimentel-Santos, Jaime Branco, Ana Cristina Fryxell, Lília Vicente, Eduardo B. Cruz,
The SPLIT project aims to introduce an interdisciplinary stratified model of care for patients with low back pain. This study aimed to explore the acceptability and identify potential barriers and facilitators regarding the upcoming implementation of this project, based on the general practitioners' and physiotherapists' perceptions.A qualitative study was carried out supported by two focus groups, which were conducted by two researchers. A focus group was carried out with each professional group. ...
Tópico(s): Clinical practice guidelines implementation
2019 - Public Library of Science | PLoS ONE
Maria J. Dinis, Rui M. F. Bezerra, Fernando M. Nunes, Albino A. Dias, Cristina Guedes, L.M.M. Ferreira, J.W. Cone, Guilhermina Marques, Ana Barros, M.A.M. Rodrigues,
The potential of crude enzyme extracts, obtained from solid state cultivation of four white-rot fungi (Trametes versicolor, Bjerkandera adusta, Ganoderma applanatum and Phlebia rufa), was exploited to modify wheat straw cell wall. At different fermentation times, manganese-dependent peroxidase (MnP), lignin peroxidase (LiP), laccase, carboxymethylcellulase (CMCase), avicelase, xylanase and feruloyl esterase activities were screened and the content of lignin as well as hydroxycinnamic acids in fermented ...
Tópico(s): Fungal Biology and Applications
2009 - Elsevier BV | Bioresource Technology
Ricardo Jorge Dinis‐Oliveira, José Alberto Duarte, Fernando Remião, Amparo Sánchez Navarro, Maria de Lourdes Bastos, Félix Carvalho,
Dexamethasone (DEX), a synthetic corticosteroid, has been successfully used in clinical practice during paraquat (PQ) poisonings due to its anti-inflammatory activity, although, as recently observed, its effects related to de novo synthesis of P-glycoprotein (P-gp), may also strongly contribute for its healing effects. The main purpose of this study was to evaluate the effects of a single high dose DEX administration, which induces de novo synthesis of P-gp, in the histological and biochemical parameters ...
Tópico(s): Poisoning and overdose treatments
2006 - Elsevier BV | Toxicology