
Tássia R. Costa, Sante E. I. Carone, Luiz Fernando Fortunato Tucci, Danilo L. Menaldo, Nathália Gonsales da Rosa-Garzon, Hamilton Cabral, Suely Vilela Sampaio,
L-amino acid oxidases isolated from snake venoms (SV-LAAOs) are enzymes that have great therapeutic potential and are currently being investigated as tools for developing new strategies to treat various diseases, including cancer and bacterial infections. The main objective of this study was to make a brief evaluation of the enzymatic stability of two Bothrops LAAOs, one isolated from Bothrops jararacussu (BjussuLAAO-II) and the other from Bothrops moojeni (BmooLAAO-I) venoms.The enzymatic activity ...
Tópico(s): Lipid Membrane Structure and Behavior
2018 - BioMed Central | The Journal of venomous animals and toxins including tropical diseases

EA Bocchi, Fabiana G. Marcondes‐Braga, Fernando Bacal, AS Ferraz, D Albuquerque, Débora Aparecida Blanco Gonsales Rodrigues,
Esta atualização da Diretriz de Insuficiência Cardíaca Crônica (IC) - 2012 surge para reavaliar as recomendações através de uma avaliação criteriosa das pesquisas (considerando-se a qualidade dos estudos), fundamental para que se atinja esse propósito. Para tanto, foi dada ênfase ao efeito em desfechos de morte, à qualidade "CONSORT" (Consolidated Standards of Reporting Trials), à descrição qualitativa e quantitativa da otimização da medicação, à população realmente incluída, às metanálises somente de ...
Tópico(s): Cardiac pacing and defibrillation studies
2012 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Alan Bonner da Silva Costa, Edson Silva,
A revista em quadrinhos Níquel Náusea, do cartunista Fernando Gonsales, retrata a vida de uma ratazana e seus ...
Tópico(s): Education and Digital Technologies
2016 - UNIVERSIDADE ESTADUAL DE MARINGÁ | Imagens da Educação

... uma tira cômica da série Níquel Náusea, de Fernando Gonsales, cartunista brasileiro. Nossas análises se centram na materialidade ...
Tópico(s): Humor Studies and Applications
2014 - UNIVERSIDADE DE SANTA CRUZ DO SUL | Signo

Luciana Barbosa Coitinho, Fernando Fumagalli, Nathália Gonsales da Rosa-Garzon, Flávio da Silva Emery, Hamilton Cabral,
Lapachol is a natural naphthoquinone with a range of biological effects, including anticancer activity. Microbial transformations of lapachol can lead to the formation of new biologically active compounds. In addition, fungi can produce secondary metabolites that are also important for drug discovery. The goal of this study was to evaluate the ability of filamentous fungi to biotransform lapachol into biologically active compounds and identify secondary metabolites produced in the presence of lapachol. ...
Tópico(s): Marine Sponges and Natural Products
2019 - Taylor & Francis | Preparative Biochemistry & Biotechnology

Marina C. Gonsales, Patrícia A. O. Ribeiro, Luiz Eduardo Betting, Marina K. M. Alvim, Carlos Guerreiro, Clarissa Lin Yasuda, Daniel Leite Góes Gitaí, Fernando Cendes, Íscia Lopes‐Cendes,
Tópico(s): Epilepsy research and treatment
2020 - Elsevier BV | Epilepsy & Behavior

In 1938, Fernando Corona, working for the construction company Azevedo Moura & Gertum, designs the Palace of Commerce in Pelotas, Rio Grande do Sul, the new headquarters of the Commercial Association. The building, the highest in the city, is undoubtedly a modern, innovative one and is acclaimed as such. In this project Corona consolidates the architectural principles which were dear to him. As a renewing architect, he uses a language of pure forms and surfaces denuded of ornament. As a conservative ...
Tópico(s): Urban Development and Societal Issues
2015 - UNIVERSIDADE DO VALE DO RIO DOS SINOS | Arquitetura Revista