Produção Nacional
Revisado por pares
Remo H.M. Furtado, Otávio Berwanger, Henrique Fonseca, Thiago Domingos Corrêa, Leonardo José Rolim Ferraz, Maura G. Lapa, Fernando G Zampieri, Viviane Cordeiro Veiga, Luciano César Pontes Azevedo, Régis Goulart Rosa, Renato D. Lópes, Álvaro Avezum, Airton L. O. Manoel, Felipe M T Piza, Priscilla A. de Martins, Thiago Lisboa, Adriano José Pereira, Guilherme Benfatti Olivato, Vicente C S Dantas, Eveline Pı́polo Milan, Otávio Gebara, Roberto Bleuel Amazonas, Monalisa B Oliveira, Ronaldo Vicente Pereira Soares, Diogo D.F. Moia, Luciana Pereira Almeida de Piano, Kleber Castilho, Roberta G.R.A.P. Momesso, Guilherme Schettino, Luiz Vicente Rizzo, Ary Serpa Neto, Flávia Ribeiro Machado, Alexandre Biasi Cavalcanti,
BackgroundThe efficacy and safety of azithromycin in the treatment of COVID-19 remain uncertain. We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, would improve clinical outcomes of patients admitted to the hospital with severe COVID-19.MethodsWe did an open-label, randomised clinical trial at 57 centres in Brazil. We enrolled patients admitted to hospital with suspected or confirmed COVID-19 and at least one additional severity criteria as follows: ...
Tópico(s): Sepsis Diagnosis and Treatment
2020 - Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
Tiago Nardi Amaral, João Francisco Marques Neto, Aline Tamires Lapa, Fernando Augusto Peres, Caio Rodrigues Guirau, Simone Appenzeller,
Localized scleroderma is a rare disease, characterized by sclerotic lesions. A variety of presentations have been described, with different clinical characteristics and specific prognosis. In scleroderma en coup de sabre (LScs) the atrophic lesion in frontoparietal area is the disease hallmark. Skin and subcutaneous are the mainly affected tissues, but case reports of muscle, cartilage, and bone involvement are frequent. These cases pose a difficult differential diagnosis with Parry-Romberg syndrome. ...
Tópico(s): Dermatological and Skeletal Disorders
2012 - Hindawi Publishing Corporation | Autoimmune Diseases
Produção Nacional
Revisado por pares
Antônio César Ferreira Guimarães, Celso Marcelo Franklin Lapa, Fernando Lamego, Denise Cunha Cabral,
This article presents an uncertainty modeling study using a fuzzy approach applied to the Westinghouse advanced nuclear reactor. The AP1000 Westinghouse Nuclear Power Plant (NPP) is provided of passive safety systems, based on thermo physics phenomenon, that require no operating actions, soon after an incident has been detected. The use of advanced passive safety systems in NPP has limited operational experience. As it occurs in any reliability study, statistically non-significant events report introduces ...
Tópico(s): Multi-Criteria Decision Making
2011 - Elsevier BV | Annals of Nuclear Energy
Produção Nacional
Revisado por pares
Francisney Pinto do Nascimento, Sérgio José Macedo-Júnior, Fernanda Rocha Lapa-Costa, Fernando Cezar‐dos‐Santos, Adair R.S. Santos,
Since the 1970s, when ATP was identified as a co-transmitter in sympathetic and parasympathetic nerves, it and its active metabolite adenosine have been considered relevant signaling molecules in biological and pathological processes in the central nervous system (CNS). Meanwhile, inosine, a naturally occurring purine nucleoside formed by adenosine breakdown, was considered an inert adenosine metabolite and remained a neglected actor on the purinergic signaling scene in the CNS. However, this scenario ...
Tópico(s): Calcium signaling and nucleotide metabolism
2021 - Frontiers Media | Frontiers in Neuroscience
Produção Nacional
Revisado por pares
Cleusa Lapa Santos, Carlos R. Moraes, Frederick Lapa Santos, Fernando Moraes, Djair Brindeiro Filho,
We describe 10 children with endomyocardial fibrosis who underwent surgical treatment between 1978 and 1999. Seven were male and 3 female, with an age range from 4 to 15 years, having a mean age of 11 years. All were in the final stage of heart failure. Three had biventricular disease, 6 had involvement of the right ventricle alone, and one had endomyocardial fibrosis confined to the left ventricle. There were 3 deaths (30%) in the postoperative period due to low cardiac output. The 7 survivors were ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2001 - Cambridge University Press | Cardiology in the Young
Produção Nacional
Revisado por pares
Samira R.V. Nascimento, C.A.B.O. Lira, Celso Marcelo Franklin Lapa, Fernando Roberto de Andrade Lima, Jair L. Bezerra, Mário A.B. Silva, Maria Elena M. Otero, Carlos Rafael Garcı́a Hernández,
• A reduced scale test facility was designed and built representing an SMR pressurizer . • Boron mixing between primary circuit and pressurizer was experimentally analyzed. • Boration and deboration processes behaved according to theoretical predictions. Small Modular Reactors, SMRs, are variants of compact modular reactors of generation III+ that present attractive features such as simplicity, enhanced safety and are economically competitive. In an iPWR (integral pressurized water reactor), the pressurizer ...
Tópico(s): Nuclear and radioactivity studies
2017 - Elsevier BV | Annals of Nuclear Energy
Cleusa Lapa Santos, Fernando Moraes, Carlos R. Moraes,
Abstract Reported here is an obstruction of the right ventricular outflow tract caused by a tuberculoma in a 15-year-old boy who presented with a ventricular septal defect. The obstruction was discovered at surgery and the tuberculous aetiology was only demonstrated histologically. To the authors' knowledge, this is the first report of a tuberculoma of the heart associated with congenital heart disease.
Tópico(s): Congenital Heart Disease Studies
1999 - Cambridge University Press | Cardiology in the Young
Produção Nacional
Revisado por pares
Simone Appenzeller, Aline Tamires Lapa, Jozélio Freire de Carvalho, Fernando Augusto Peres, Yehuda Shoenfeld,
Tópico(s): Diabetes and associated disorders
2011 - Springer Science+Business Media | Current Rheumatology Reports
Produção Nacional
Revisado por pares
Fernando Moraes, Cleuza Lapa, Sheila Hazin, Euclides Tenório, Cláudio A Gomes, Carlos R. Moraes,
To identify life expectancy after surgery for endomyocardial fibrosis (EMF) and the events that influence it.Eighty-three patients with EMF underwent endocardial decortication and atrioventricular valve replacement or repair, between December 1977 and December 1997. There were 66 (79.6%) female and 17 (20.4%) male patients, ranging in age from 4 to 59 years (mean, 31). Thirty-seven (44.5%) had biventricular disease, 34 (41.0%) had disease of the right ventricle alone and 12 (14.5%) had EMF confined to ...
Tópico(s): Eosinophilic Esophagitis
1999 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Produção Nacional
Revisado por pares
Mariana Postal, Aline Tamires Lapa, Nailú Angélica Sinicato, Karina de Oliveira Peliçari, Fernando Augusto Peres, Lílian Tereza Lavras Costallat, Paula Teixeira Fernandes, Roberto Marini, Simone Appenzeller,
Tumor necrosis factor alpha (TNF-α) is deeply related to pathogenesis of neurodevelopmental disorders, especially depression. The aim of this study was to explore potential relationships between sera TNF-α levels and mood and anxiety disorders in systemic lupus erythematosus (SLE) patients. We included 153 consecutive SLE patients (women 148; median age 30; range 10–62) and 40 (women 37; mean age 28.5; range 12–59) age- and sex-matched healthy controls. Mood and anxiety disorders were determined through ...
Tópico(s): Tryptophan and brain disorders
2016 - BioMed Central | Journal of Neuroinflammation
Produção Nacional
Revisado por pares
Mariana Freschi Bombini, Fernando Augusto Peres, Aline Tamires Lapa, Nailú Angélica Sinicato, Beatriz Ricato Quental, Ágatha de Souza Melo Pincelli, Tiago Nardi Amaral, Caroline Cristina Gomes, Ana Paula del Rio, João Francisco Marques-Neto, Lilian T. L. Costallat, Paula Teixeira Fernandes, Fernando Cendes, Letícia Rittner, Simone Appenzeller,
Tópico(s): Advanced Chemical Sensor Technologies
2018 - Elsevier BV | Autoimmunity Reviews
Produção Nacional
Revisado por pares
Fernando Moraes, Cleusa Lapa Santos, Vital Lira, Carlos R. Moraes,
Congenital aneurysm of the right atrium is described in a 1-year-old girl who presented with cardiomegaly and symptoms of paroxysmal supraventricular tachycardia. Echocardiography and cineangiography both established the definitive diagnosis and surgical resection was successful. The rarity of this condition is pointed out and its main features outlined.
Tópico(s): Pericarditis and Cardiac Tamponade
2001 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Produção Nacional
Revisado por pares
Thiago Araújo de Melo, Fernando Silva Guimarães, José Roberto Lapa e Silva,
Abstract Background The Five Times Sit-to-Stand Test (FTSST) has been found reliable, safe and valid for measuring healthy adults’ lower limb muscle strength and for determining balance control, fall risk, and exercise capacity among older examinees. We believe that the FTSST has the potential to be a straightforward, low cost and valuable tool for identifying muscle disability and functional status following critical illness. The aim of our study was to establish the applicability, safety, and psychometric ...
Tópico(s): Frailty in Older Adults
2022 - BioMed Central | Archives of Physiotherapy
Produção Nacional
Revisado por pares
Rodrigo Bernardo Serafim, Márcio Soares, Fernando A. Bozza, José Roberto Lapa e Silva, Felipe Dal‐Pizzol, Maria Carolina Paulino, Pedro Póvoa, Jorge I. Salluh,
Subsyndromal delirium (SSD) is a frequent condition and has been commonly described as an intermediate stage between delirium and normal cognition. However, the true frequency of SSD and its impact on clinically relevant outcomes in the intensive care unit (ICU) remains unclear.We performed a systematic search in PubMed, Embase, CINAHL, Cochrane Library, and PsychINFO, with no language restrictions, up to 1 October 2016 to identify publications that evaluated SSD in ICU patients.The six eligible studies ...
Tópico(s): Healthcare Decision-Making and Restraints
2017 - BioMed Central | Critical Care
Produção Nacional
Revisado por pares
Tiago Nardi Amaral, Fernando Augusto Peres, Aline Tamires Lapa, João Francisco Marques-Neto, Simone Appenzeller,
To perform a systematic review of neurologic involvement in Systemic sclerosis (SSc) and Localized Scleroderma (LS), describing clinical features, neuroimaging, and treatment. We performed a literature search in PubMed using the following MeSH terms, scleroderma, systemic sclerosis, localized scleroderma, localized scleroderma “en coup de sabre”, Parry–Romberg syndrome, cognitive impairment, memory, seizures, epilepsy, headache, depression, anxiety, mood disorders, Center for Epidemiologic Studies ...
Tópico(s): Dermatologic Treatments and Research
2013 - Elsevier BV | Seminars in Arthritis and Rheumatism
Produção Nacional
Revisado por pares
Jorge I. Salluh, Cássia Righy, Márcio Soares, Fernando A. Bozza, José Roberto Lapa e Silva, Bernardo Rangel Tura, Patrı́cia T. Bozza, Carolina García‐Vidal,
Our aim was to review the literature on the prevalence and impact of critical-illness related corticosteroid insufficiency (CIRCI) on the outcomes of patients with severe community-acquired pneumonia (CAP).We reviewed Cochrane, Medline, and CINAHL databases (through July 2008) to identify studies evaluating the adrenal function in severe CAP. Main data collected were prevalence of CIRCI and its mortality.We screened 152 articles and identified 7 valid studies. Evaluation of adrenal function varied, ...
Tópico(s): Sepsis Diagnosis and Treatment
2010 - Elsevier BV | Journal of Critical Care
Produção Nacional
Revisado por pares
Fernando Moraes, Cleuza Lapa, Cristina Ventura, Rejane Conceição Santana, Euclides Tenório, Cláudio A Gomes, Carlos R. Moraes,
Congenital supravalvular mitral stenosis is a rare malformation characterized by the presence of a shelf-like fibrous membrane, with 1 or 2 small orifices, covering and obstructing the mitral valve. The membrane is positioned closely to the mitral valve (and sometimes it is attached to it); therefore, a preoperative diagnosis is inevitably difficult, even with the use of biplane echocardiography. Two patients with supravalvular mitral stenosis aged 3 years and 3 months are described. In 1 patient, ...
Tópico(s): Congenital Heart Disease Studies
2002 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Débora G. Xisto, Luciana Landa Farias, Halina Cidrini Ferreira, Miguel Rossi Picanço, Daniel Amitrano, José Roberto Lapa e Silva, Eva Negri, Thaís Mauad, D. Carnielli, Luiz Fernando Ferraz da Silva, Vera Luíza Capelozzi, Débora S. Faffe, Walter A. Zin, Patrícia R. M. Rocco,
This study tested the hypotheses that chronic allergic inflammation induces not only bronchial but also lung parenchyma remodeling, and that these histologic changes are associated with concurrent changes in respiratory mechanics. For this purpose, airway and lung parenchyma remodeling were evaluated by quantitative analysis of collagen and elastin, immunohistochemistry (smooth-muscle actin expression, eosinophil, and dendritic cell densities), and electron microscopy. In vivo (airway resistance, ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2005 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine
Produção Nacional
Bruna Schons Ribeiro, Leonardo Alencastro Vanin Dutra de Souza, Isadora Horn Lapa, Fernando Shinoske Tagawa de Lemos Pires, Dioni Paulo Pastorio,
Apresenta-se neste trabalho uma Revisão Sistemática da Literatura acerca da metodologia ativa de ensino Just-in-Time Teaching empregada dentro das subáreas Ensino de Física e Educação em Ciências. Após seleção de 123 periódicos nacionais e internacionais, a busca inicial resultou em 41 artigos – filtrados posteriormente e reduzidos a 34. Estes trabalhos subdividem-se em: Trabalho Teórico (n = 8), Apresentação de Propostas (n = 1) e Proposta com Aplicação (n = 25). É predominante o desenvolvimento de estudos ...
Tópico(s): Education during COVID-19 pandemic
2022 - SOCIEDADE BRASILEIRA DE FÍSICA | Revista Brasileira de Ensino de Física
Nuno Lapa, Fernando Marques, Aurora Rodrigues,
Mass wasting events are the main processes of sedimentary dynamics that affect the marine environment and which, due to their spatial and temporal variability, are difficult to study and evaluate. Affecting the marine floor, between the coastline and the abyssal plain, these processes are triggered by multiple causes, having different magnitudes and causing drastic changes and impacts on the marine environment and human activities. In this paper, the submarine landslide susceptibility affecting ...
Tópico(s): Geological formations and processes
2020 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Produção Nacional
Revisado por pares
Fernando Moraes, Cleusa Lapa Santos, Carlos R. Moraes,
We describe an asymptomatic 1-year-old boy who presented a continuous murmur, and was found to have a tunnel between the right atrium and the aorta. The definitive diagnosis was established by both echocardiography and aortography, and surgical interruption of the tunnel was successful. We emphasise the rarity of this condition, and discuss its major features.
Tópico(s): Congenital Heart Disease Studies
2004 - Cambridge University Press | Cardiology in the Young
Produção Nacional
Lino Bittencourt Monteiro, Márcio Fernando Swider de SOUZA,
Tripes tem causado danos em nectarina no município da Lapa (PR) e o controle não tem sido satisfatório. Os objetivos deste estudo foram determinar as espécies de tripes em nectarina na floração e a eficiência dos inseticidas cloridrato de formetanato e spinosad no controle de tripes na floração. Foram utilizados dois métodos de amostragem: armadilhas cromotrópicas e batida de ramos. Foram identificados Frankliniella occidentalis (Pergande), F. schultzei (Trybom), F. rodeos Moulton, F. serrata Moulton, ...
Tópico(s): Insect-Plant Interactions and Control
2013 - UNIVERSIDADE FEDERAL DO PARANÁ | Scientia Agraria
Produção Nacional
Revisado por pares
Renata Coura Borges, Vanessa Godoy Caldas, Fernando Lamego, Marcos Manoel Ferreira, Celso Marcelo Franklin Lapa,
The Cunha Canal watershed, which is located in the municipality of Rio de Janeiro, suffered severe environmental degradation in recent decades due to rapid urban population growth. However, this substantial growth did not result in social development; instead, it exacerbated existing environmental and social problems. This study aimed to evaluate the pollution of the Canal do Cunha and Guanabara Bay, using GIS for mapping based on the result of the heavy metal concentrations obtained by spectrometry ( ...
Tópico(s): Water Quality and Pollution Assessment
2014 - Elsevier BV | Marine Pollution Bulletin
Produção Nacional
Revisado por pares
Adriana Seber, Adriana Aparecida Siviero‐Miachon, Ana Cristina Sayuri Tanaka, Angela Maria Spínola-Castro, Antônio Carlos Carvalho, Antônio Sérgio Petrilli, Carla Macedo, Clarissa Carvalho Fongaro Nars, Claudia Naufel Terzian, Cláudio Galvão de Castro, Cleusa Cavalcanti Lapa Santos, C Guerra, Dáfne Cardoso Bourguignon da Silva, Debora Bassi, Estela Azeka, Fabiana Aragão Feitosa, Fernando Kazuaki Hamamoto, Gilberto Szarf, Henrique Manoel Lederman, Humberto João Rigon, Ieda Biscegli Jatene, Isabele Coelho Fonseca da Mota, Jeferson Adriano Perrud, José Soares, Julian Arango Gutiérrez, Juliana Pepe Marinho Perin, Juliana dos Santos Soares, Liane Hulle Catani, Liliana Yu Tsai, Livia Cristina Vianna, Marcelo Goulart Paiva, Marcelo José dos Santos, Márcia Marcelino de Souza Ishigai, Maria Suely Bezerra Diógenes, Maria Teresa de Seixas Alves, Maria Tereza Castro Piedade, Mariana Parreiras, Mônica Cypriano, N. Negrini, Orlando Campos Filho, Paula Andrade Figueiredo, Paulo Eduardo Novaes, Paulo Roberto Camargo, Priscila dos Santos Maia, Renata Petrilli, Rodrigo Genaro Arduini, Roseane Vasconcelos Gouveia, Suzana Barbosa Miranda Teruya, Valdir Ambrósio Moisés, Vera Lúcia Lins de Morais,
Tópico(s): Healthcare Regulation
2013 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Paula Lapa, M. Paula M. Marques, Jorge Isidoro, Fernando Barata, Gracinda Costa, João Pedroso Lima,
To test a software application for the quantification of metabolic heterogeneity and to evaluate its superiority in relation to visual interpretation. To investigate if a quantitative analysis adds information to the interpretation of 18F-FDG-PET/CT. The study analyzed 215 patients with a 18F-FDG-PET/CT done for the initial staging of lung cancer between March 2011 and December 2015. The study included 57 (26.5%) women and 158 (73.5%) men, with ages ranging from 34 to 88 years (mean ± SD: 67.23 ± 10.04). ...
Tópico(s): Medical Imaging Techniques and Applications
2017 - Elsevier BV | Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
Produção Nacional
H Kneese de Melo, Fernando Moraes Neto, C Lapa, Carlos R. Moraes,
Congenital aneurysm or enlargement of the right atrium is a rare condition. Two children operated on at the age of 14 months and 11 years old for congenital aneurysm of the right atrium are reported. Both presented cardiomegaly and symptoms of paroxysmal supraventricular tachycardia. Diagnosis was established by echocardiography. Surgical resection was successful. Both patients are free of symptoms and their chest X-ray and echocardiogram are normal. The first patient is now in her 17th postoperative ...
Tópico(s): Cardiac tumors and thrombi
2019 - Brazilian Society of Cardiovascular Surgery | Brazilian Journal of Cardiovascular Surgery
Produção Nacional
Revisado por pares
Aline Tamires Lapa, Mariana Postal, Nailú Angélica Sinicato, Weslley Geraldo Ferreira, Bruna Siqueira Bellini, Paula Teixeira Fernandes, Letícia Rittner, Roberto Marini, Fernando Cendes, Simone Appenzeller,
Objective There have been few studies in which the prevalence of cerebral atrophy in childhood‐onset systemic lupus erythematosus (SLE) was evaluated using magnetic resonance imaging (MRI) volumetric measurements. This study was undertaken to determine the prevalence of cerebral and corpus callosum atrophy in childhood‐onset SLE and to determine the possible relationships between atrophy and clinical, laboratory, and treatment features of the disease. Methods We included 76 patients with childhood‐ ...
Tópico(s): Cytomegalovirus and herpesvirus research
2016 - Wiley | Arthritis & Rheumatology
Marcus Barreto Conde, Fernando Augusto Fiúza de Melo, Ana Maria Campos Marques, Ninarosa Calzavara Cardoso, Valéria Góes Ferreira Pinheiro, Paulo de Tarso Roth Dalcin, Almério Machado, Antônio Carlos Moreira Lemos, Antônio Ruffino-Netto, Betina Durovni, Clemax Couto Sant’Anna, Dinalva Soares Lima, Domênico Capone, Dráurio Barreira, Eliana Dias Matos, Fernanda Carvalho de Queiroz Mello, Fernando Cezar David, Giovanni Marsico, Jorge Barros Afiune, José Roberto Lapa e Silva, Leda Fátima Jamal, María Alice da Silva Telles, Mário Hiroyuki Hirata, Margareth Pretti Dalcolmo, Marcelo Fouad Rabahi, Michelle Cailleaux-Cesar, Moisés Palaci, Nelson Morrone, Renata Leborato Guerra, Reynaldo Dietze, Silvana Spíndola de Miranda, Solange Cavalcante, Susie Andries Nogueira, Tatiana Senna Galvão Nonato, Terezinha Martire, Vera Maria Nader Galesi, Valdério do Valle Dettoni,
Diariamente novos artigos científicos sobre tuberculose (TB) são publicados em todo mundo. No entanto, é difícil para o profissional sobrecarregado na rotina de trabalho acompanhar a literatura e discernir o que pode e deve ser aplicado na prática diária juntos aos pacientes com TB. A proposta das "III Diretrizes para TB da Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)" é revisar de forma crítica o que existe de mais recente na literatura científica nacional e internacional sobre TB e apresentar ...
Tópico(s): Cystic Fibrosis Research Advances
2009 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Produção Nacional
Revisado por pares
Fernando Lamego, Abner Duarte Soares, André S. Aguiar, Celso Marcelo Franklin Lapa, Antonio Carlos Ferreira Guimarães,
Abstract The effective contribution of nuclear energy will depend on various factors related to economics, safety, public acceptance and sustainability. To assure, however, the nuclear energy development, reactor accident impacts, as Fukushima, must be evaluated in a predictive way. Environmental assessment models are used for evaluating the radiological impact of potential releases of radionuclides from nuclear reactors to the environment. It is important to evaluate, to the extent possible, the ...
Tópico(s): Groundwater flow and contamination studies
2013 - Elsevier BV | Progress in Nuclear Energy
Produção Nacional
Revisado por pares
Lígia Sarmet Cunha Farah Rabello, Pedro Póvoa, José Roberto Lapa e Silva, Luciano César Pontes Azevedo, Fernando José da Silva Ramos, Thiago Lisboa, Márcio Soares, Jorge I. Salluh,
Describe the patterns of C-reactive protein relative changes in response to antibiotic therapy in critically ill cancer patients with healthcare-associated pneumonia (HCAP) and its ability to predict outcome.Secondary analysis of a prospective cohort of critically ill cancer patients with HCAP. CRP was sampled every other day from D0 to D6 of antibiotic therapy. Patients were classified according to an individual pattern of CRP-ratio response: fast - CRP at D4 of therapy was <0.4 of D0 CRP; slow - a continuous ...
Tópico(s): Pancreatitis Pathology and Treatment
2017 - Elsevier BV | Journal of Critical Care