Produção Nacional
Revisado por pares
Yoshihisa Kobayashi, Geoffrey R. Oxnard, Elizabeth F. Cohen, Navin R. Mahadevan, Joao V. Alessi, Yin P. Hung, Arrien A. Bertram, David E. Heppner, Maurício Fernando Silva Almeida Ribeiro, Karina Perez Sacardo, Rodrigo Saddi, Mariana Petaccia de Macêdo, Rafael B. Blasco, Jiaqi Li, Kari J. Kurppa, Tom Nguyen, Emma Voligny, Guruprasad Ananda, Roberto Chiarle, Artur Katz, Michael Tolstorukov, Lynette M. Sholl, Pasi A. Jänne,
Abstract The clinical significance of gene fusions detected by DNA-based next generation sequencing remains unclear as resistance mechanisms to EGFR tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer. By studying EGFR inhibitor-resistant patients treated with a combination of an EGFR inhibitor and a drug targeting the putative resistance-causing fusion oncogene, we identify patients who benefit and those who do not from this treatment approach. Through evaluation including RNA- ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2022 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Maurício Fernando Silva Almeida Ribeiro, Franciele Hinterholz Knebel, Fabiana Bettoni, Rodrigo Saddi, Karina Perez Sacardo, Felipe Sales Nogueira Amorim Canedo, Joao V. Alessi, Andrea Kazumi Shimada, José Flávio Gomes Marin, Anamaria A. Camargo, Artur Katz,
Abstract The survival outcomes of the FLAURA trial support osimertinib as the new standard of care for untreated patients harboring activating mutations in the epidermal growth factor receptor ( EGFR ). Despite the initial response, disease progression invariably occurs. Although uncommon, BRAF V600E mutation arises as a unique mechanism of resistance, and thus far, no prospective studies are available to support concurrent EGFR/BRAF blockade. We report a case of impressive radiological and ctDNA response ...
Tópico(s): Quinazolinone synthesis and applications
2021 - Nature Portfolio | npj Precision Oncology
Produção Nacional
Revisado por pares
Maurício Fernando Silva Almeida Ribeiro, Joao V. Alessi, Leandro Jonata de Carvalho Oliveira, Aline Bobato Lara Gongora, Karina Perez Sacardo, Bruna Migliavacca Zucchetti, Andrea Kazumi Shimada, Felipe de Galiza Barbosa, Olavo Feher, Artur Katz,
to report outcomes of four cases of chemo-refractory RET-rearranged non-small cell lung carcinomas (NSCLCs) treated with alectinib in a single center.we retrospectively assessed and reported the activity and tolerability of alectinib 600 mg twice daily in advanced and chemo-refractory RET-rearranged NSCLC patients treated in a Brazilian institution. Identification of RET rearrangements was performed using the FoundationOne® next-generation sequencing (NGS) platform.The four patients herein reported ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2019 - Elsevier BV | Lung Cancer
Produção Nacional
Revisado por pares
Maurício Fernando Nunes Teixeira, Andreá Maria Eleutério de Barros Lima Martins, Roger Keller Celeste, Fernando Neves Hugo, Juliana Balbinot Hilgert,
OBJETIVO: Avaliar a associação entre resiliência e qualidade de vida relacionada à saúde bucal, por meio de uma abordagem hierárquica baseada em um modelo teórico conceitual em uma coorte de idosos do Rio Grande do Sul. MÉTODOS: Foi conduzido um estudo transversal aninhado a um estudo de coorte, em 2008. Foram avaliados 498 idosos de Carlos Barbosa, Rio Grande do Sul. As medidas avaliadas foram sociodemográficas, comportamentos de saúde, qualidade de vida relacionada à saúde bucal, medida pelo Oral ...
Tópico(s): Health disparities and outcomes
2015 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Eduardo Radovanovic, Mauricio Fernando Gozzi, María do Carmo Gonçalves, Inez Valéria Pagotto Yoshida,
Rubbers resulting from the hydrosilylation reaction between poly(methylsiloxane), and 1,3,5,7-tetramethyl-1,3,5,7-tetravinylcycletetrasiloxane, have been pyrolyzed to silicon oxycarbide ceramics, with ceramic yield varying as a function of the mixture composition. The rubber–ceramic conversion process was investigated by 13C and 29Si nuclear magnetic resonance and infrared spectroscopies, thermogravimetric analysis and density measurements. The composition of the ceramic products was determined ...
Tópico(s): Glass properties and applications
1999 - Elsevier BV | Journal of Non-Crystalline Solids
Produção Nacional
Revisado por pares
Mauricio Fernando Gozzi, Inez Valéria Pagotto Yoshida,
Abstract A polymeric precursor to SiC based on the mixture between poly(methylsilane) and tetra-allylsilane was prepared. The structural evolution by which this precursor system undergoes until its conversion to SiC was monitored by IR, Raman, 13C and 29Si MAS NMR spectroscopies, and by XRD techniques. Thermal and density measurements were also run. The role of the hydrosilylation reaction between SiH and CC moities on the ceramic conversion was also investigated.
Tópico(s): Advanced materials and composites
1997 - Elsevier BV | European Polymer Journal
Mauricio Fernando Gozzi, Inez Valéria Pagotto Yoshida,
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermal and Photochemical Conversion of Poly(methylsilane) to Poly(carbosilane)Mauricio F. Gozzi and I. Valeria P. YoshidaCite this: Macromolecules 1995, 28, 21, 7235–7240Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/ma00125a028https://doi.org/10.1021/ma00125a028research-articleACS PublicationsRequest reuse permissionsArticle Views213Altmetric-Citations15LEARN ...
Tópico(s): Synthesis and properties of polymers
1995 - American Chemical Society | Macromolecules
Pablo González-Blasco, Thais Raquel Pinheiro, Mauricio Fernando Ulloa-Rodríguez, Nohora Angulo-Calderón,
Instruction on ethics for physicians and medical students is associated with the humanistic perspective required in medical training. In today’s world, teaching ethics and fostering humanism demands innovative solutions, inasmuch as teaching theory alone is not enough. The broad fi eld of human emotions opens up new and promising of possibilities for emotional education to support ethical training in a way that is consistent, modern and effi cient. This is the reason for using the humanities in ...
Tópico(s): Innovations in Medical Education
2009 - University of La Sabana | Persona y Bioética
Produção Nacional
Revisado por pares
Marcello Moro Queiroz, Karina Perez Sacardo, Mauricio Fernando Ribeiro, Luiza Lara Gadotti, Rodrigo Saddi, Leandro Jonata de Carvalho Oliveira, Rudinei Diogo Marques Linck, Marcelo Cruz, Romualdo Barroso‐Sousa, Marina Sahade, Tatiana Strava Corrêa, Max S. Mano, Daniele Xavier Assad, Andrea Kazumi Shimada, Artur Katz,
Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have been recently developed and introduced into clinical practice. We retrospectively analyzed data from patients with confirmed HR+/HER2 metastatic breast cancer treated with hormonal therapy in combination with ribociclib (R), palbociclib (P), or abemaciclib (A). Outcomes: median progression-free survival (mPFS), time to treatment discontinuation (mTTD), and objective response rate (ORR). Between January 2016 - June 2021, 142 patients were treated with ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2023 - Elsevier BV | Cancer Treatment and Research Communications
Martha Liliana Ospina Gutiérrez, Mauricio Fernando Ulloa-Rodríguez, Lina María Ruíz-Moreno,
Las autolesiones no suicidas (ALNS) son conductas autolesivas sin objetivo suicida que afecta a los adolescentes con una prevalencia del 17-18%. Se caracterizan por ser lesiones autoinflingidas, principalmente en las extremidades y el abdomen. La psicopatología está sujeta a la presencia de una desregulación emocional, en la que se busca el enmascaramiento del dolor emocional con el físico. Se realizó una revisión bibliográfica con búsqueda en bases de datos, incluyendo palabras clave en inglés y ...
Tópico(s): Suicide and Self-Harm Studies
2019 - Elsevier BV | Medicina de Familia SEMERGEN
Carlos Brotons, Miguel Ángel Royo‐Bordonada, L. Álvarez-Sala, Pedro Armario, R Artigao, Pedro Conthe, Fernando de Álvaro, Ana de Santiago, Albert Roque, Jm Lobos, Antonio Maiques, Jaume Marrugat, Dı́dac Mauricio, Fernando Rodríguez-Artalejo, S. Sans, C. Suárez,
Tópico(s): Health and Lifestyle Studies
2004 - Elsevier BV | Atención Primaria
Carlos Brotons, Miguel Ángel Royo‐Bordonada, L. Álvarez-Sala, Pedro Armario, R Artigao, Pedro Conthe, Fernando de Álvaro, Ana de Santiago, A. L�pez Gil, José Ma Lobos, Antonio Maiques, Jaume Marrugat, Dı́dac Mauricio, Fernando Rodríguez-Artalejo, Susana Sans, Carmen Suárez,
We are pleased to present the European Guidelines on Cardiovascular Disease Prevention, translated and adapted by the Interdisciplinary Spanish Committee for Cardiovascular Disease Prevention. This guide is focused on the prevention of cardiovascular disease as a whole, recommending the SCORE model for risk assessment and placing priority on the care of patients and high-risk individuals. The objective is to prevent premature death due to CVD by means of dealing with its related risk factors in ...
Tópico(s): Health and Lifestyle Studies
2004 - Ministry of Health of Spain | Revista Española de Salud Pública
Produção Nacional
Revisado por pares
Marcos R. Maurício, Fernando Manso, Marcos H. Kunita, D. Velasco, A. C. Bento, Edvani C. Muniz, Gizilene Maria de Carvalho, Adley F. Rubira,
Tópico(s): Polymer Foaming and Composites
2011 - Elsevier BV | Composites Part A Applied Science and Manufacturing
José Luis Hernández‐Stefanoni, Miguel Santiago, Jean‐François Mas, Charlotte Wheeler, Juan Andres‐Mauricio, Fernando Tun‐Dzul, Stephanie P. George‐Chacón, Gabriela Reyes-Palomeque, Blanca Castellanos-Basto, Raúl Abel Vaca, Juan Manuel Dupuy,
Abstract Background Reliable information about the spatial distribution of aboveground biomass (AGB) in tropical forests is fundamental for climate change mitigation and for maintaining carbon stocks. Recent AGB maps at continental and national scales have shown large uncertainties, particularly in tropical areas with high AGB values. Errors in AGB maps are linked to the quality of plot data used to calibrate remote sensing products, and the ability of radar data to map high AGB forest. Here we suggest ...
Tópico(s): Forest ecology and management
2020 - Springer Science+Business Media | Carbon Balance and Management
Carlos Brotons, M.Á. Royo-Bordonada, L. Álvarez-Sala, Pedro Armario, R Artigao, Pedro Conthe, Fernando de Álvaro, Ana de Santiago, Albert Roque, José María Lobos, Antonio Maiques, Jaume Marrugat, Dı́dac Mauricio, Fernando Rodríguez‐Artalejo, S. Sans, C. Suárez,
Esta guia se centra en la prevencion de la enfermedad cardiovascular en su conjunto, recomienda el modelo SCORE para valorar el riesgo y prioriza la atencion a los pacientes y sujetos de alto riesgo. Los pacientes de alto riesgo deben incrementar su actividad fisica, elegir dietas cardiosaludables y los fumadores abandonar el tabaco. La decision de iniciar el tratamiento farmacologico dependera del riesgo cardiovascular y de posibles lesiones de organos diana. Se incluye un anexo con recomendaciones ...
Tópico(s): Cardiac Health and Mental Health
2005 - Elsevier BV | Clínica e Investigación en Arteriosclerosis
Mauricio Galleguillos, Fernando Gimeno, Cristóbal Puelma, Mauricio Zambrano‐Bigiarini, Antonio Lara, Maisa Rojas,
Climate change (CC) along with Land Use and Land Cover Change (LULCC) have a strong influence in water availability in already fragile Mediterranean ecosystems. In this work the Soil and Water Assessment Tool (SWAT) was implemented for the 2006–2018 period in a rainfed catchment of central Chile (36°) to test the hypothesis that adaptive plantation strategies could mitigate the impacts of climate change and increase streamflow. We also hypothesize that afforestation with exotic tree plantations will ...
Tópico(s): Tree-ring climate responses
2021 - Elsevier BV | Journal of Hydrology
Produção Nacional
Revisado por pares
Renata Lazari Sandoval, Cibele Masotti, Mariana Petaccia de Macêdo, Maurício Fernando Silva Almeida Ribeiro, Ana Carolina Rathsam Leite, Sibele I. Meireles, Rodrigo Medeiros Bovolin, Fernando C. Santini, Rodrigo Ramella Munhoz, Denis L. Jardim, Artur Katz, Anamaria A. Camargo, Gustavo dos Santos Fernandes, Maria Isabel Achatz,
Li-Fraumeni syndrome (LFS) is rare in the worldwide population, but it is highly prevalent in the Brazilian population because of a founder mutation,
Tópico(s): Cancer Genomics and Diagnostics
2021 - Lippincott Williams & Wilkins | JCO Global Oncology
Produção Nacional
Revisado por pares
J. Fernando Arévalo, Andrés F. Lasave, Igor Kozak, Saba Al Rashaed, Eman Al Kahtani, Maurício Maia, Michel Eid Farah, Caroline Cutolo, Miguel Brito, Claudia Osorio, Patricia Navarro, Lihteh Wu, María H. Berrocal, Virgilio Morales-Cantón, Martín Serrano, Federico Graue‐Wiechers, Nelson Alexandre Sabrosa, Arturo Alezzandrini, Roberto Gallego‐Pinazo, J. Fernando Arévalo, T.Y.A. Liu, Lihteh Wu, Andrés F. Lasave, Michel Eid Farah, Maurício Maia, Fernando M. Penha, Eduardo B. Rodrigues, Virgilio Morales-Cantón, Jans Fromow-Guerra, José Luis Guerrero-Naranjo, José Dalma-Weiszhausz, Raúl Vélez-Montoya, Hugo Quiroz–Mercado, Ferdinand Rodriguez, Flor E. Gómez, Anne Charlotte Brieke, A. Goveto, María H. Berrocal, Vanessa Cruz-Villegas, Federico Graue‐Wiechers, David Lozano-Rechy, Emiliano Fulda-Graue, José A. Roca, Ángeles Hernández, Mario Saravia, Ariel Schlaen, Jorge Rojas, Mariana Ingolotti, Marcos Pereira de Ávila, L. Carla, J.A. Cardillo, Rodrigo Jorge, Cristián Carpentier, J. Verdaguer T, J.I. Verdaguer D, G Sepúlveda, Arturo Alezzandrini, B. Garcia, Marcelo Zas, Roberto Gallego‐Pinazo, M. Díaz-Llopis, Rosa Dolz‐Marco, M. Figueroa, Inés Contreras, Diego Ruiz-Casas,
Purpose To assess the effectiveness and safety of an intravitreal injection of 1.25 mg bevacizumab (IVB) as a preoperative adjunct to small-gauge pars plana vitrectomy (PPV) compared with PPV alone in eyes with tractional retinal detachment secondary to proliferative diabetic retinopathy. Methods This prospective, double-masked, randomized, multicenter, active-controlled clinical trial enrolled 224 eyes of 224 patients between November 2013 and July 2015. All eyes underwent a baseline examination including ...
Tópico(s): Retinal and Macular Surgery
2019 - Elsevier BV | American Journal of Ophthalmology
Produção Nacional
Revisado por pares
Marta S. Figueroa, Inés Contreras, Susana Noval, Lihteh Wu, J. Fernando Arévalo, Miguel Ángel Serrano, Andrés F. Lasave, Michel Eid Farah, Maurício Maia, Fernando M. Penha, Eduardo B. Rodrigues, Virgilio Morales-Cantón, Jorge Jans Fromow-Guerra, José Luis Guerrero-Naranjo, José Dalma-Weiszhausz, Hugo Quiroz-Mercado, Raúl Vélez-Montoya, Francisco J. Rodríguez, F. Enrique Gómez, Anne Charlotte Brieke, María H. Berrocal, Vanessa Cruz-Villegas, Federico Graue‐Wiechers, David Lozano-Rechy, Enrique Ariza-Camacho, José A. Roca, R. Chico, Mario Saravia, Ariel Schlaen, A. P. C. Lupinacci, Maria Noel Gabin, Marcos Pereira de Ávila, L. Carla, J.A. Cardillo, Joel Vidal, Thomas Carpentier, Juan Ignacio Verdaguer, D. G. Sepúlveda, Arturo Alezzandrini, B. Garcia, Guido Agustin Bregliano, Gustavo Alvira, Pedro Flor, Fernando Stalin Jimenez Jaramillo, M. Díaz-Llopis, Roberto Gallego-Pinazo, Patricia Udaondo, David Salom, M. Figueroa, Inés Contreras, Diego Ruiz-Casas,
Purpose To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). Methods Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of proliferative vitreoretinopathy or coexisting ocular pathologies were excluded. Surgery consisted of 23-G vitrectomy with endolaser photocoagulation of retinal breaks and fluid-air-gas (12% ...
Tópico(s): Retinal Diseases and Treatments
2013 - SAGE Publishing | European Journal of Ophthalmology
Andrea Castro, Fernándo Rodríguez, Martha Flórez, Patricia López, Bianca Curotto, Daniela Martínez, Aitor Zabala-Lopez de Maturana, María Cecilia Lardone, Cárol Palma, Verónica Mericq, Mauricio Ebensperger, Fernando Cassorla,
Are copy number variations (CNVs) in the pseudoautosomal regions (PARs) frequent in subjects with Y-chromosome microdeletions and can they lead to abnormal stature and/or neuropsychiatric disorders? Only subjects diagnosed with azoospermia factor (AZF)b+c deletions spanning to the end of the Y chromosome (i.e. terminal deletions) harbor Y isochromosomes and/or cells 45,X that lead to pseudoautosomal gene CNVs, which were associated with abnormal stature and/or neuropsychiatric disorders. The microdeletions ...
Tópico(s): Chromatin Remodeling and Cancer
2016 - Oxford University Press | Human Reproduction
Erica C. Koch Hein, Maysa Vilbert, Ian Hirsch, Maurício Fernando Silva Almeida Ribeiro, Thiago Pimentel Muniz, Cynthia Fournier, Khaled Abdulalem, Erick Figueiredo Saldanha, Erika Martínez, Anna Spreafico, David H. Hogg, Marcus O. Butler, Samuel D. Saibil,
Immune checkpoint inhibitors (ICI) cemiplimab and pembrolizumab have revolutionized the treatment of advanced cutaneous squamous cell carcinoma (cSCC). We aimed to evaluate the effectiveness and safety of ICI in a real-world cSCC population, including patients with conditions that would exclude clinical trial participation. In this single-center, retrospective cohort study, we included all non-trial patients with advanced cSCC treated with ICI between 2017 and 2022. We evaluated investigator-assessed ...
Tópico(s): CAR-T cell therapy research
2023 - Multidisciplinary Digital Publishing Institute | Cancers
Produção Nacional
Janaína Oliveira Gonçalves, Maurício Fernando Oliveira de Miranda, Edson Gonçalves Júnior,
Este artigo tem o objetivo de apresentar uma breve reflexão sobre a parceria da família e escola em tempos de COVID-19, considerando alguns aspectos pedagógicos, econômicos e jurídicos. A metodologia utilizada neste estudo é a pesquisa bibliográfica, que orienta a discussão sobre o tema, a partir dos autores que pesquisam a temática da parceria família e escola, como Coutrim, Carvalho E Almeida (2012); Barroso (2014); Rinaldi (2016), dentro outros. A reflexão pautou-se na importância do diálogo, parceria ...
Tópico(s): Education Pedagogy and Practices
2020 - | Revista Científica Multidisciplinar Núcleo do Conhecimento
Produção Nacional
Revisado por pares
Tiago Maurício Francoy, Fernando de Faria Franco, David W. Roubik,
Morphometric methods permit identification of insect species and are an aid for taxonomy. Quantitative wing traits were used to identify male euglossine bees. Landmark- and outline-based methods have been primarily used independently. Here, we combine the two methods using five Euglossa. Landmark-based methods correctly classified 84% and outline-based 77%, but an integrated analysis correctly classified 91% of samples. Some species presented significantly high reclassification percentages when ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2012 - Springer Science+Business Media | Apidologie
Produção Nacional
Revisado por pares
Paulo Roberto Pagliosa, Maurício Cantor, Fernando Scherner, Mariana Beatriz Paz Otegui, Aurea Luiza Lemes-Silva, Cintia Dalcuche Leal Martins, Giorgia Freitas Alves, Alessandra Fonseca, Paulo Antunes Horta,
Artificial habitats have become common in coastal areas worldwide and may influence the structure and functioning of benthic ecosystems. We analyze the influence of piers on the benthic morphofunctional groups of rocky seaweeds and of soft bottom macrofauna in the channel of Conceição Lagoon (southern Brazil). The main impact is a reduction in the luminosity available for photosynthetic activity which is directly related to a decrease in the biomasses of sediment microphytobenthos and of more highly ...
Tópico(s): Coral and Marine Ecosystems Studies
2012 - UNIVERSIDADE DE SÃO PAULO | Brazilian Journal of Oceanography
Produção Nacional
Revisado por pares
Vivian C. Konigame, Erica Rosanna Siu, Carine Royer, Thaís F.G. Lucas, Catarina S. Porto, Fernando Maurício Francis Abdalla,
The aim of the present study was to investigate the activation of rapid signaling events by 17β-estradiol in the rat uterus. 17β-Estradiol induced a rapid increase of total [3H]-inositol phosphate accumulation in the whole uterus and endometrium, but not in the myometrium. The effect of 17β-estradiol in the endometrium was blocked by phospholipase C (PLC) inhibitor (U73122), estrogen receptors antagonist (ICI 182,780), exportin CRM1 inhibitor (leptomycin B) and selective inhibitor of the SRC family of ...
Tópico(s): Endometriosis Research and Treatment
2011 - Elsevier BV | Steroids
Produção Nacional
Revisado por pares
André Rodrigues, Ulrich G. Mueller, Heather D. Ishak, Maurício Bacci, Fernando C. Pagnocca,
We profiled the microfungal communities in gardens of fungus-growing ants to evaluate possible species-specific ant–microfungal associations and to assess the potential dependencies of microfungal diversity on ant foraging behavior. In a 1-year survey, we isolated microfungi from nests ofCyphomyrmex wheeleri, Trachymyrmex septentrionalis andAtta texana in Central Texas. Microfungal prevalence was higher in gardens ofC. wheeleri (57%) than in the gardens ofT. septentrionalis (46%) andA. texana (35%). ...
Tópico(s): Plant Parasitism and Resistance
2011 - Oxford University Press | FEMS Microbiology Ecology
Produção Nacional
Revisado por pares
Daniel Coelho da Silva, Wyara Aparecida Araújo de Medeiros, Isabel de Fátima Correia Batista, Daniel C. Pimenta, Ivo Lebrun, Fernando Maurício Francis Abdalla, Maria Regina Lopes Sandoval,
We have isolated a new muscarinic protein (MT-Mlα) from the venom of the Brazilian coral snake Micrurus lemniscatus.This small protein, which had a molecular mass of 7,048Da, shared high sequence homology with three-finger proteins that act on cholinergic receptors. The first 12 amino acid residues of the N-terminal sequence were determined to be: Leu-Ile-Cys-Phe-Ile-Cys-Phe-Ser-Pro-Thr-Ala-His.The MT-Mlα was able to displace the [(3)H]QNB binding in the hippocampus of rats. The binding curve in competition ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2011 - Elsevier BV | Life Sciences
Produção Nacional
Revisado por pares
José Henrique de Faria, Francis Kanashiro Meneghetti,
... deste trabalho consiste em analisar a forma como Maurício Tragtenberg e Fernando Cláudio Prestes Motta concebem a burocracia. Os objetivos ...
Tópico(s): Social and Economic Solidarity
2011 - FUNDAÇÃO GETÚLIO VARGAS | Revista de Administração de Empresas
Produção Nacional
Tiago Amâncio Novo, Antônio Carlos Pedrosa Soares, Carlos Maurício Noce, Fernando F. Alkmim, Ivo Dussin,
The Araçuaí and Ribeira orogens are a Cambrian-Neoproterozoic belt that extends from the eastern edge of the San Francisco craton to the Atlantic Ocean, south of parallel 15 º. The connection between these orogens is roughly situated along the 21 º S parallel. High-grade metamorphic rocks are exposed in the southern Araçuaí Belt, SE Minas Gerais, reflecting a deep crustal level. The Divino Suite comprises mafic- to felsisc charnockites, metamorphosed in granulite facies, interpreted as an expanded ...
Tópico(s): Geography and Environmental Studies
2010 - Sociedade Brasileira de Geologia | Revista Brasileira de Geociências
Produção Nacional
Revisado por pares
Sayuri Sales, Rodrigo Portes Ureshino, Renato Tavares dos Santos Pereira, Milene Schmidt Luna, Marcelo Pires de Oliveira, Norma Yamanouye, Rosely Oliveira Godinho, Soraya S. Smaili, Catarina S. Porto, Fernando Maurício Francis Abdalla,
The aim of the present study was to investigate the effects of different periods of ovariectomy and 17β-estradiol replacement on apoptotic cell death and expression of members of the Bcl-2 family in the rat hippocampus. Hippocampi were obtained from rats in proestrus, ovariectomized (15 days, 21 days and 36 days), ovariectomized for 15 days and then treated with 17β-estradiol for 7 or 21 days, and rats ovariectomized and immediately treated with 17β-estradiol for 21 days. The expression of Bcl-2 ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2010 - Elsevier BV | Life Sciences