Cristina Cunha, Franco Aversa, João F. Lacerda, Alessandro Busca, Oliver Kurzai, Matthias Grube, Jürgen Löffler, Johan Maertens, Alain S. Bell, Antonio Inforzato, Elisa Barbati, Bruno Almeida, Pedro Santos e Sousa, Anna Maria Barbui, Leonardo Potenza, Morena Caira, Fernando Rodrigues, Giovanni Salvatori, Livio Pagano, Mario Luppi, Alberto Mantovani, Andrea Velardi, Luigina Romani, Agostinho Carvalho,
The soluble pattern-recognition receptor known as long pentraxin 3 (PTX3) has a nonredundant role in antifungal immunity. The contribution of single-nucleotide polymorphisms (SNPs) in PTX3 to the development of invasive aspergillosis is unknown.
Tópico(s): Leptospirosis research and findings
2014 - Massachusetts Medical Society | New England Journal of Medicine
José Manuel Luján, Pedro Piqueras, Joaquín De la Morena, Fernando Redondo,
This paper studies the behavior of a Euro 6 diesel engine tested under dynamic conditions corresponding to different real driving emissions (RDE) scenarios. RDE cycles have been performed in an engine test bench by simulating its operation in a long van application. A computer tool has been designed to define the cycle accounting for different dynamic characteristics and driver behaviors to study their influence on CO2 and pollutant emissions, particularly CO, THC, and NOX. Different dynamic parameters ...
Tópico(s): Transportation Planning and Optimization
2022 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Produção Nacional
Revisado por pares
Larissa G. Pinto, Guilherme R. Souza, Ricardo Kusuda, Alexandre H. Lopes, Morena B. Sant’Anna, Fernando Q. Cunha, S. H. Ferreira, Thiago M. Cunha,
Tópico(s): Ion channel regulation and function
2019 - Springer Science+Business Media | Molecular Neurobiology
Fernando Palero, R. A. Both, Antonio Arribas, Adrian J. Boyce, José Mangas, Agustín Martín Izard,
The Alcudia Valley is intensely mineralized, with a large number of Pb-Zn-Ag-Cu deposits hosted by Neoproterozoic and Paleozoic sedimentary rocks. Five distinct types of deposits have been recognized. The most significant mineralizing events were related to the two major phases of deformation (HD1, HD2) and granite emplacement during the Hercynian orogeny. Stable isotope and lithogeochemical data demonstrate that the metals, as well as sulfur and carbon, were sourced from the local sedimentary rocks. ...
Tópico(s): earthquake and tectonic studies
2003 - | Economic Geology
Raúl Moreno, José‐Luis Díez, José‐Antonio Diarte, Fernando Macaya, José‐María de la Torrre Hernández, Oriol Rodríguez‐Leor, Ramiro Trillo, Juan H. Alonso‐Briales, Ignacio J. Amat‐Santos, Rafael Romaguera, José‐Francisco Díaz, Beatriz Vaquerizo, Soledad Ojeda, Ignacio Cruz‐González, Daniel Morena‐Salas, Armando Pérez de Prado, Fernando Sarnago, Pilar Portero, Alejandro Gutiérrez, Fernándo Alfonso, Eduard Bosch, Eduardo Pinar, José‐Ramón Ruiz‐Arroyo, Valeriano Ruiz‐Quevedo, Jesús Jiménez‐Mazuecos, Fernando Lozano, José Ramón Rumoroso, Enrique Novo, Francisco Javier Irazusta, Bruno García del Blanco, José Moreu, Sara Ballesteros-Pradas, Araceli Frutos, Manuel Villa, Eduardo Alegría‐Barrero, Rosa Lázaro, Emilio Paredes-Galán,
Abstract Background During COVID‐19 pandemic in Spain, elective procedures were canceled or postponed, mainly due to health care systems overwhelming. Objective The objective of this study was to evaluate the consequences of interrupting invasive procedures in patients with chronic cardiac diseases due to the COVID‐19 outbreak in Spain. Methods The study population is comprised of 2,158 patients that were pending on elective cardiac invasive procedures in 37 hospitals in Spain on the 14th of March ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2020 - Wiley | Catheterization and Cardiovascular Interventions
Produção Nacional
Revisado por pares
Renata Gonçalves Dias, Sandra Coccuzzo Sampaio, Morena B. Sant’Anna, Fernando Q. Cunha, José Marı́a Gutiérrez, Bruno Lomonte, Yara Cury, Gisele Picolo,
Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient's lives. These are multi-mediated pathologies that cannot be effectively protected and/or treated. Therefore, the aim of this study was to establish a new model of acute arthritis, using a Lys49-PLA2 (Bothrops asper myotoxin II; MT-II) to induce articular inflammation. The articular inflammation was induced by MT-II (10 μg/joint) injection ...
Tópico(s): Ion channel regulation and function
2017 - BioMed Central | The Journal of venomous animals and toxins including tropical diseases
Fernando J. Palero-Fernández, Agustín Martín Izard,
The Alcudia Valley mineral field was an important lead ore producer in Spain during the 19th and the 20th centuries. Based on mineralogical, lithological, structural, morphological and geochemical characteristics, five main types of lead and zinc deposits have been defined in the district. The most important of these are Pb–Zn post-tectonic veins (type E), which represent 70% of the total number of mineral occurrences and include the biggest mines of the area. These deposits show a paragenetic zoning ...
Tópico(s): Geochemistry and Geologic Mapping
2005 - Elsevier BV | Journal of Geochemical Exploration
Peter Rossing, Stefan D. Anker, Gerasimos Filippatos, Bertram Pitt, Luís M. Ruilope, Andreas L. Birkenfeld, Janet B. McGill, Sylvia E. Rosas, Amer Joseph, Martin Gebel, Luke Roberts, Markus F. Scheerer, George L. Bakris, Rajiv Agarwal, Diego Aizenberg, Inés Bartolacci, Diego Besada, Julio Bittar, Mariano Chahin, Alicia Elbert, Elizabeth Gelersztein, Alberto Liberman, Laura Maffei, Federico Pérez Manghi, Hugo Sanabria, Augusto Vallejos, Gloria Viñes, Alfredo Wassermann, Walter P. Abhayaratna, Shamasunder Acharya, Elif I. Ekinci, Darren Lee, Richard J. MacIsaac, Peak Mann Mah, Craig Nelson, David Packham, Alexia Pape, Simon D. Roger, Hugo Stephenson, Michael Suranyi, Gary Wittert, Elizabeth Vale, Peter G. Colman, David Colquhoun, Chris Ellis, Kim Joshua, Eugenia Pedagogos, Paul Regal, Duncan J. Topliss, James Vandeleur, Johan Verjans, Gary Wittert, Katie-Jane Wynne, Martin Clodi, Christoph Ebenbichler, Evelyn Fließer-Görzer, Ursula Hanusch, Michael Krebs, Karl Lhotta, Bernhard Ludvik, Gert Mayer, Peter Neudorfer, Bernhard Paulweber, Rudolf Prager, Wolfgang Preiß, Friedrich C. Prischl, G. Schernthaner, Harald Sourij, Martin Wiesholzer, Heinz Drexel, Rainer Oberbauer, Hans‐Robert Schönherr, Peter Doubel, W. Engelen, Pieter Gillard, Jean‐Michel Hougardy, Jean-Marie Krzesinski, Bart Maes, Marijn M. Speeckaert, Koen Stas, Luc Van Gaal, Hilde Vanbelleghem, Francis Duyck, André Scheen, Daniela Antunes, Roberto Botelho, Cláudia Brito, Luís Henrique Santos Canani, Maria Eugênia Fernandes Canziani, Maria Cerqueira, Rogério de Paula, Freddy G. Eliaschewitz, Carlos Eduardo Poli‐de‐Figueiredo, Adriana Costa e Forti, Miguel Nasser Hissa, Maurilo Leite, Emerson de Lima, Irene L. Noronha, Bruno Paolino, Nathalia Paschoalin, Raphael Paschoalin, Roberto Pecoits–Filho, Marcio Pereira, Evandro Portes, Dalton Bertolim Précoma, Rosângela Réa, Miguel C. Riella, João Eduardo Nunes Salles, Eduardo Vasconcellos, Sérgio Vencio, Marcelo Rodrigues Bacci, Lília Nigro Maia, Aline Sterque Villacorta, Emiliya Apostolova, Radostina Boshnyashka, Ghassan Farah, Dimitar Georgiev, Valentina Gushterova, Neli Klyuchkova, Mariya Lucheva, Petya Manova, Dotska Minkova, Boyan Nonchev, Mariyana Pichmanova, Zhulieta Prakova, Rangel Rangelov, Rosen Rashkov, Pavel Stanchev, Bilyana Stoyanovska-Elencheva, Zhivko Tagarev, Theodora Temelkova-Kurktschieva, S Vasileva, Mariana Yoncheva-Mihaylova, Angel Marinchev, Mariya Miteva, Paul E. Barré, Brian Carlson, James Conway, Serge Cournoyer, R Dumas, Sameh Fikry, Richard Goluch, Pavel Hamet, Randolph Hart, Sam Henein, Joanne Liutkus, François Madore, Valdemar Martinho, Giuseppe Mazza, Philip A. McFarlane, Dennis D. O’Keefe, Sean D. Peterson, Daniel Schwartz, Daniel Shu, Andrew Steele, Guy Tellier, Karthik Tennankore, Sheldon W. Tobe, George Tsoukas, Richard Tytus, Louise Vitou, Michael Walsh, S. John Weisnagel, Igor Wilderman, Jean‐François Yale, Fadia El Boreky, Alan Kelly, Lawrence A. Leiter, Ivor Teitelbaum, Jorge Cobos, Juan Godoy, Fernando González, Sergio Lobos, Juan Carlos Palma, Juan Carlos Prieto Dominguez, Eliana Reyes, Carmen Romero, Víctor Saavedra, Mario Vega, Marcelo Gabriel Medina, Paola Varleta, Ruifang Bu, Cai H, Nan Chen, Qinkai Chen, Dejun Chen, Jinluo Cheng, Youping Dong, Junwu Dong, Tianjun Guan, Chuan‐Ming Hao, Wen Huang, Fangfang Jiang, Minxiang Lei, Ling Li, Zhonghe Li, Xuemei Li, Jingmei Li, Yan Li, Xinling Liang, Bo Liang, Fang Liu, Yinghong Liu, Yuantao Liu, Zhihong Liu, Gang Long, Guoyuan Lu, Weiping Lu, Yibing Lu, Ping Luo, Jianhua Ma, Zhaohui Mo, Jianying Niu, Ai Peng, Jiansong Shen, Feixia Shen, Bingyin Shi, Qing Su, Zhuxing Sun, Shuifu Tang, Nanwei Tong, Hao Wang, Xinjun Wang, Guixia Wang, Jianqin Wang, Yangang Wang, Li Wang, Jiali Wei, Tianfeng Wu, Chao-Qing Wu, Xing Changying, Fei Xiong, Xudong Xu, Ning Xu, Tiekun Yan, Jinkui Yang, Aiping Yin, Longyi Zeng, Hao Zhang, Yanlin Zhang, Ying Zhang, Wenjing Zhao, Zhiquan Zhao, Hongguang Zheng, Ling Zhong, Dalong Zhu, Yongze Zhuang, Yuming Du, Yi Fang, Weiying Guo, Sheng Jiang, Jian Kuang, Dongmei Li, Hongmei Li, Yinan Li, Yuxiu Li, Liu Jian, Yu Liu, Heng Miao, Wen Peng, Lihua Wang, Mingtong Xu, Liyong Zhong, Jun Zhu, Clara Arango, Sandra Barrera, Nelly Beltrán López, Diego Benitez, Guillermo Blanco, Andrés Cadena, Julián Coronel, Carlos Cure, Carlos E. Durán, Alexander Ariel Padrón González, Gustavo Guzmán, Eric Hernández, Jaime Ibarra, Carlos Jaramillo, Nicolás Jaramillo, William Kattah, Dora I. Molina, Gregorio Sánchez, Mónica Terront, Freddy Trujillo, Miguel Urina‐Triana, Ruben Vargas, Iván Villegas, Hernán Yupanqui, Édgar Arcos, Gustavo Aroca, Germán Barreto, Andrés Bermúdez, Rodrigo Botero, Tatiana Cárdenas, Wilmer Figueroa, Mónica Jaramillo,
Finerenone reduced the risk of kidney and cardiovascular events in people with chronic kidney disease (CKD) and type 2 diabetes in the FIDELIO-DKD and FIGARO-DKD phase 3 studies. Effects of finerenone on outcomes in patients taking sodium-glucose cotransporter 2 inhibitors (SGLT2is) were evaluated in a prespecified pooled analysis of these studies.Patients with type 2 diabetes and urine albumin-to-creatinine ratio (UACR) ≥30 to ≤5,000 mg/g and estimated glomerular filtration rate (eGFR) ≥25 mL/min/1.73 ...
American Diabetes Association
Fábia Maria de Santana, Ana Paula de Araújo Machado, Patrícia Poleto Monhol, Lígia Ajaime Azzalis, Virgínia Junqueira, David Feder, Leela Morená, Fernando Luiz Affonso Fonseca,
Introduction: Front of the persistence of tuberculosis in several municipalities in the country, the Ministry of Health (MS) established the National Tuberculosis Control Plan (NTCP), whose goals were to integrate 100% of the Brazilian municipalities in the fight against the disease. Objective: To evaluate the performance of tuberculosis (TB) control actions and services of the Family Health Strategies in the city of Salgueiro-PE. Methods: Cross-sectional, quantitative and descriptive survey study ...
Tópico(s): Health Education and Validation
2018 - UNIVERSIDADE DE SÃO PAULO | Journal of Human Growth and Development
Fernando González Bernáldez, J. Fernández Haeger, C. Levassor, J. Merino, Lucía Cevallos Ramírez, A. Pou, Fabián Ortiz Sancho,
Prospección integrada de las dehesas en la Sierra Morena (Espana). Se describe la prospección integrada de los pastizales de Sierra Morena por un equipo interdisciplinar que interpreta las imágenes aéreas infrarrojas (1/8000) mediante muestreo estratificado y análisis cuantitativo. Se estudian las correspondencias entre vegetación y factores tales como la litologia, las transferencias, la denudación, la acumulación y los ciclos de erosión. Se han realizado análisis distintos para el matorral y para ...
Tópico(s): Land Use and Ecosystem Services
1980 - Éditions Belin | L’Espace géographique
... public order (3).As recent as 1455, the morena of the city of Valen-11) Discussions of Fernando's foreign policy nave not given enough attention ...
Tópico(s): Historical and Linguistic Studies
1986 - | Sharq Al-Andalus
S. Cuervo, Fernando Tornos, Baruch Spiro, César Casquet Martín,
Oxygen and carbon isotopes of the hydrothermal minerals in the Colmenar-Santa Barbara skarn suggest that fluids of the main hydrothermal stage (grandite/clinopyroxene and actinolite+magnetite) are of likely magmatic origin. There is only a minor input of modified surficial fluids during the late hydrothermal stages.8 345 values of sulphides indicate that sulphur derives from the hosting volcanosedimentary pile, the likely origin of most of the iron in the skarn. During hydrothermal circulation, magmatic ...
Tópico(s): Geological and Tectonic Studies in Latin America
1996 - | Geogaceta
Enrique Rey, C. MORENA ELOLA‐OLASO, Fernando Rodríguez‐Artalejo, G. Richard Locke, M Díaz-Rubio,
Summary Background Overall success of prophylactic strategies against non‐steroidal anti‐inflammatory drug (NSAID) complications depends on the use of gastroprotective drugs. Aim We examined the use of antisecretory drugs in NSAID users in the general population of Spain. Participants and Methods In 2002, a phone interview was conducted with 2500 persons representative of the general population of Spain. Using a validated questionnaire, we asked about the use of NSAID, aspirin and antisecretory drugs, ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2006 - Wiley | Alimentary Pharmacology & Therapeutics
José Fernando Simancas, D. Martínez Poyatos, Inmaculada Expósito, António Azor, Francisco González Lodeiro,
We have investigated the stratigraphy, structure and metamorphism of the boundary between the Ossa Morena Zone (OMZ) and the Central Iberian Zone (CIZ), two significant continental portions of the Variscan Iberian Massif. The OMZ/CIZ contact is marked by a strongly deformed and metamorphosed NW–SE trending narrow band, namely, the Central Unit, in which partially retrogressed eclogites are included. During the Middle-Late Devonian the CIZ overthrust the OMZ, and in the footwall km-scale recumbent ...
Tópico(s): earthquake and tectonic studies
2001 - Elsevier BV | Tectonophysics
C. Llorente Abarca, Cristian Puerta, M. Sánchez Encinas, J.M. De La Morena Gallego, Fernando Chamorro, J. Martinez De Hurtado, D. Rengifo Abbad,
Objetivo: Exponer la implantación de nuestro programa de prostatectomía radical laparoscópica (PRL). Se presenta la metodología y el plan de trabajo seguido en nuestro Centro. La implantación del programa de PRL se hace en diferentes de fases coincidentes de manera parcial cronológicamente: fase de preparatoria, fase de reconversión programada, fase de desarrollo y fase de análisis. La primera es un periodo de aprendizaje de la técnica laparoscópica y de adquisición de equipamiento. La fase de reconversión ...
Tópico(s): Surgical Simulation and Training
2005 - Elsevier BV | Actas Urológicas Españolas
Produção Nacional
Revisado por pares
Jaqueline de Souza Cavalcanti, João Leandro de Paula Ferreira, Paula Morena de Souza Guimarães, J Vidal, Luís Fernando de Macedo Brígido,
Dolutegravir is a second-generation integrase strand transfer inhibitor (InSTI) that has been recently approved by the FDA to treat antiretroviral therapy-naive as well as treatment-experienced HIV-infected individuals, including those already exposed to the first-generation InSTI. Despite having a different mutational profile, some cross-resistance mutations may influence its susceptibility. The aim of this study was to evaluate the impact of a raltegravir-containing salvage regimen on dolutegravir ...
Tópico(s): HIV/AIDS Research and Interventions
2014 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Fernando A. Monteiro Santos, J. Pous, Eugénio P. Almeida, Pilar Queralt, Álex Marcuello, Hugo Matías, L. A. Mendes Victor,
The transition between the South Portuguese Zone (SPZ) and the Ossa Morena Zone (OMZ) is made up of a major geosuture, which is indicated by the Beja-Acebuches ophiolite. Several geological data suggest that this suture is the result of an oblique collision, with a northward propagation, between the SPZ and OMZ. From the structural point of view the OMZ is much more complex than the adjacent Central Iberian Zone and the SPZ. The frequently complicated internal structure is the result of superposition ...
Tópico(s): earthquake and tectonic studies
1999 - Elsevier BV | Tectonophysics
J. Enrique Domínguez‐Muñoz, Fernando Carballo, Julio de la Morena, María José Sánchez García, J. Miguel de Diego, Luís Rábago, Miguel Ángel Simón,
Abstract The usefulness and clinical applicability of quantitative plasma polymorphonuclear elastase determinations in the diagnosis of the severity of acute pancreatítis was analysed in a multicentre study and was compared with the usual prognostic systems of Ranson and Osborne et al. The study comprised 182 patients, 154 with a mild episode of acute pancreatitis and 28 with a severe episode, defined by the development of major complications or a fatal outcome. In the severe cases neutrophilic ...
Tópico(s): Liver Disease Diagnosis and Treatment
1991 - Oxford University Press | British journal of surgery
S. M. Lima, Fernando Corfú, A.M.R. Neiva, J.M.F. Ramos,
The build-up of large magmatic complexes can proceed piecemeal over periods of several million years through sequences of complex processes of magma production, differentiation, assimilation, final crystallization and subsequent metasomatic modification. All these stages can produce or modify minerals used as geochronometers, such as zircon, monazite and titanite. The present study exemplifies such complex relationships, also demonstrating how a systematic approach with comprehensive sampling and ...
Tópico(s): High-pressure geophysics and materials
2012 - Oxford University Press | Journal of Petrology
Jesús Chacón, Iziar Sanz, María Dolores Rubio, Maria L. de la Morena, Esperanza Gutiérrez Díaz, María Luisa Mateos, Fernando Baquero,
El objetivo del presente estudio es utilizando dos técnicas complementarias de detección del virus del papiloma humano (VPH) (captura de híbridos [CH] y reacción en cadena de la polimerasa [PCR]), relacionar el estudio citológico y/o la biopsia de cérvix con la presencia de distintos genotipos del VPH, para conocer la influencia de éstos en la producción de lesiones precancerosas y cáncer cervical, así como relacionar la carga viral con la presencia de VPH-AR (alto riesgo) determinados por PCR. Se han ...
Tópico(s): Cervical Cancer and HPV Research
2007 - Elsevier BV | Enfermedades Infecciosas y Microbiología Clínica
Aurora López-Munguira, Fernando Nieto, Diego Morata,
Abstract Chlorites from Cambrian basaltic vesicular lavas, characterized by relatively high X c (0.81-0.98), gave temperatures of formation of 285 to 350 ° C (Cathelineau's empirical geothermometer). Both the X c and temperature calculations gave results which were too high for the diagenetic conditions indicated by the interbedded shale mineralogy. The HRTEM and XRD studies indicate the absence of smectite layers in these chlorites; i.e. according to lattice images, the actual value of X c is 1. The ...
Tópico(s): Geochemistry and Elemental Analysis
2002 - Cambridge University Press | Clay Minerals
Inmaculada Expósito, José Fernando Simancas, Francisco González Lodeiro, Ф. Беа, P. Montero, Karmah Salman,
The high-temperature metamorphism recorded in the Valuengo and Monesterio areas constitutes a rare occurrence in the Ossa-Morena Zone of Southwest Iberia, where low-grade metamorphism dominates. The metamorphism of the Valuengo area has been previously considered either Cadomian or Variscan in age, whereas that of Monesterio has been interpreted as a Cadomian imprint. However, these areas share important metamorphic and structural features that point towards a common tectonometamorphic evolution. ...
Tópico(s): earthquake and tectonic studies
2003 - Elsevier BV | Journal of Structural Geology
Guillermo Booth‐Rea, José Fernando Simancas, António Azor, José Miguel Azañón, Francisco González Lodeiro, Paulo E. Fonseca,
Multi-equilibrium thermobarometry shows that low-grade metapelites (Cubito-Moura schists) from the Ossa–Morena Zone underwent HP–LT metamorphism from 340–370 °C at 1.0–0.9 GPa to 400–450 °C at 0.8–0.7 GPa. These HP–LT equilibriums were reached by parageneses including white K mica, chlorite and chloritoid, which define the earliest schistosity (S1) in these rocks. The main foliation in the schists is a crenulation cleavage (S2), which developed during decompression from 0.8–0.7 to 0.4–0.3 GPa at increasing ...
Tópico(s): earthquake and tectonic studies
2006 - Elsevier BV | Comptes Rendus Géoscience
Aurora López-Munguira, Fernando Nieto,
Abstract This study examines the evolution of the texture, structure, and chemical composition of rocks derived from clastic materials of the Ossa-Morena Zone (Hesperian Massif, Spain). Previous studies of phyllosilicates in these rocks (by X-ray diffraction, scanning electron microscopy with energy-dispersive X-ray analysis, and electron microprobe) indicated a temperature decrease from bottom (epizone conditions) to top (diagenetic conditions) of the rock section. At the nanometer scale, phyllosilicate ...
Tópico(s): Iron oxide chemistry and applications
2000 - Cambridge University Press | Clays and Clay Minerals
Miriam Ejarque, Fernando Guerrero‐Pérez, Nuria de la Morena, Anna Casajoana, N. Virgili, Rafael López‐Urdiales, Elsa Maymó‐Masip, Jordi Pujol Gebellí, Amador García Ruiz de Gordejuela, Manuel Pérez-Maraver, Sílvia Pellitero, Sonia Fernández‐Veledo, Joan Vendrell, Núria Vilarrasa,
Abstract We aimed to explore the relationship between GLP-1 receptor ( GLP-1R ) expression in adipose tissue (AT) and incretin secretion, glucose homeostasis and weight loss, in patients with morbid obesity and type 2 diabetes undergoing bariatric surgery. RNA was extracted from subcutaneous (SAT) and visceral (VAT) AT biopsies from 40 patients randomized to metabolic gastric bypass, sleeve gastrectomy or greater curvature plication. Biochemical parameters, fasting plasma insulin, glucagon and area under ...
Tópico(s): Diabetes Treatment and Management
2019 - Nature Portfolio | Scientific Reports
Morena Fasano, Carminia Maria Della Corte, Giuseppe Viscardi, Raimondo Di Liello, Fernando Paragliola, Francesca Sparano, Maria Lucia Iacovino, Anna Castrichino, Francesca Doria, Antonello Sica, Floriana Morgillo, Giuseppe Colella, Giampaolo Tartaro, Salvatore Cappabianca, D. Testa, Gaetano Motta, Fortunato Ciardiello,
Head and neck cancers (HNC) represent the seventh most frequent cancer worldwide, with squamous cell carcinomas as the most frequent histologic subtype. Standard treatment for early stage diseases is represented by single modality surgery or radiotherapy, whereas in the locally advanced and recurrent or metastatic settings a more aggressive multi-modal approach is needed with locoregional intervention and/or systemic therapies. Epidermal Growth Factor Receptor (EGFR) plays an important role in HNC ...
Tópico(s): Peptidase Inhibition and Analysis
2021 - SAGE Publishing | Therapeutic Advances in Medical Oncology
María Eugenia Sánchez Lorda, Fernando Sarrionandia-Ibarra Eguidazu, B. Ábalos, M. Carrracedo, Luis Eguíluz Alarcón, José Ignacio Gil Ibarguchi,
Tópico(s): Geochemistry and Geologic Mapping
2013 - Springer Science+Business Media | International Journal of Earth Sciences
Aurora López-Munguira, Fernando Nieto, Diego Morata,
Tópico(s): Evolution and Paleontology Studies
1998 - E. Schweizerbart | Neues Jahrbuch für Mineralogie - Abhandlungen Journal of Mineralogy and Geochemistry
Francisco Moya, Juan Carlos López,
... In-Building EnvironmentsF.J. Villanueva, J. de la Morena, J. Barba, F. Moya and J.C. LopezA Comprehensive Solution for Ambient IntelligenceFelix J. Villanueva, Francisco Moya, Fernando Rincon Santofimia, David Villa and Jesus Barba et ...
2002 - Wiley | Networks
Fernando Sarrionandia-Ibarra Eguidazu, M. Carracedo Sánchez, Luis Eguíluz Alarcón, B. Ábalos, Javier Caride Rodríguez, Christian Pin, José Ignacio Gil Ibarguchi,
Volcanic rocks of Cambrian age from Zafra (Ossa-Morena Zone, Iberian Massif) are the result of rift processes that affected Cadomian arc units accreted to the NW edge of Gondwana during the Neoproterozoic–Early Cambrian transition. Tephrite to rhyolite volcanics define an alkaline transitional association (Coombs type). Basic–ultrabasic rocks exhibit typical alkaline REE-patterns, strongly enriched in LREE with respect to HREE. Two parental magmas are identified, one with a mantle signature, lack ...
Tópico(s): earthquake and tectonic studies
2012 - Elsevier BV | Tectonophysics