Juan F. Herrero, Andrea Cecilia Parrado, Fernando Cerveró,
Ketoprofen is a non-steroidal antiinflammatory drug (NSAID) which provides effective analgesia in situations of pain provoked by tissue inflammation. However, the location of its analgesic effects, (peripheral tissues versus central nervous system), have not been clearly identified and separated. In the present study the effectiveness of ketoprofen was examined in two different types of experiments: (i) Open field behavioural tests in conscious rats, and (ii) spinal cord nociceptive reflexes (single ...
Tópico(s): Neuropeptides and Animal Physiology
1997 - Elsevier BV | Neuropharmacology
Juan Antonio González, Mariana Rosa, María F. Parrado, Mirna Hilal, Fernando E. Prado,
Morphological and physiological responses of seedlings to different solar UV–B irradiances were evaluated in two varieties of quinoa (Chenopodium quinoa Willd.), a crop species from Andean region of South America. Cristalina and Chucapaca varieties were grown at 1965 m a.s.l in a glasshouse under natural light conditions for 18 days, and then transferred to outdoors under near-ambient (+UV–B) and strongly reduced (−UV–B) solar UV–B radiation. Exposition to −UV–B increased cotyledon area and seedling height ...
Tópico(s): Spaceflight effects on biology
2009 - Elsevier BV | Journal of Photochemistry and Photobiology B Biology
Darío García-García, Emilio Parrado-Hernández, Fernando Díaz-de-María,
This paper proposes a novel similarity measure for clustering sequential data. We first construct a common state space by training a single probabilistic model with all the sequences in order to get a unified representation for the dataset. Then, distances are obtained attending to the transition matrices induced by each sequence in that state space. This approach solves some of the usual overfitting and scalability issues of the existing semi-parametric techniques that rely on training a model ...
Tópico(s): Bayesian Modeling and Causal Inference
2010 - Elsevier BV | Pattern Recognition
Juan Camilo Gómez Zapata, Cristhian Parrado Rodríguez, Theresa Frimberger, Fernando Barragán-Ochoa, Fabio Brill, Kerstin Büche, Michael Krautblatter, Michael Langbein, Massimiliano Pittore, Hugo Rosero‐Velásquez, Elisabeth Schöepfer, Harald Spahn, Camilo Zapata-Tapia,
The inhabitants of Latacunga living in the surrounding of the Cotopaxi volcano (Ecuador) are exposed to several hazards and related disasters. After the last 2015 volcanic eruption, it became evident once again how important it is for the exposed population to understand their own social, physical, and systemic vulnerability. Effective risk communication is essential before the occurrence of a volcanic crisis. This study integrates quantitative risk and semi-quantitative social risk perceptions, ...
Tópico(s): Seismology and Earthquake Studies
2021 - Multidisciplinary Digital Publishing Institute | Sustainability
Produção Nacional
Revisado por pares
Eloy Povedano, Fernando Henrique Cincotto, Concepción Parrado, Paula Díez, Alfredo Sánchez, Thiago C. Canevari, Sérgio Antônio Spínola Machado, José M. Pingarrón, Reynaldo Villalonga,
A novel nanocomposite material consisting of reduced graphene oxide/Rh nanoparticles was prepared by a one-pot reaction process. The strategy involved the simultaneous reduction of RhCl3 and graphene oxide with NaBH4 and the in situ deposition of the metal nanoparticles on the 2D carbon nanomaterial planar sheets. Glassy carbon electrode coated with this nanocomposite was employed as nanostructured support for the cross-linking of the enzyme laccase with glutaraldehyde to construct a voltammperometric ...
Tópico(s): Biotin and Related Studies
2016 - Elsevier BV | Biosensors and Bioelectronics
David Guerrero‐Gómez, José Antonio Mora-Lorca, Beatriz Sáenz‐Narciso, Francisco José Naranjo-Galindo, Fernando Muñoz-Lobato, Cristina Parrado‐Fernández, Julen Goikolea, Ángel Cedazo‐Mínguez, Christopher D. Link, Christian Néri, María Dolores Sequedo, Rafael P. Vázquez‐Manrique, Elena Fernández-Suárez, Veit Goder, Roser Pané, Elisa Cabiscol, Peter Askjaer, Juan Cabello, Antonio Miranda‐Vizuete,
In the presence of aggregation-prone proteins, the cytosol and endoplasmic reticulum (ER) undergo a dramatic shift in their respective redox status, with the cytosol becoming more oxidized and the ER more reducing. However, whether and how changes in the cellular redox status may affect protein aggregation is unknown. Here, we show that C. elegans loss-of-function mutants for the glutathione reductase gsr-1 gene enhance the deleterious phenotypes of heterologous human, as well as endogenous worm ...
Tópico(s): Autophagy in Disease and Therapy
2019 - Springer Nature | Cell Death and Differentiation
Rembrandt Koppelaar, Sreenivaasa Pamidi, Enikő Hajósi, Lucia Herreras, Pascal Leroy, Ha-Young Jung, Amba Concheso, Radha Daniel, Fernando B. Francisco, Cristina Parrado, Siro Dell’Ambrogio, Fabiana Guggiari, Deborah Leone, Alessandro Fontana,
The reuse and recycling of critical raw materials is limited, as waste electrical and electronic recycling focuses on base and precious metals, and device component reuse is in its infancy. To help to address this issue this paper provides the conceptual design of a Digital Product Passport based circular supply management system. To enable the recovery of critical raw materials at component and material levels for reuse and recycling. The works include an assessment of existing critical raw materials ...
Tópico(s): Sustainable Supply Chain Management
2023 - Multidisciplinary Digital Publishing Institute | Sustainability
Jorge Enrique Machado‐Alba, Anyi Liliana Jiménez-Morales, Yulieth Carolina Moran-Yela, Ilsa Yadira Parrado-Fajardo, Luis Fernando Valladales‐Restrepo,
Introduction Biological drugs open new possibilities to treat diseases for which drug therapy is limited, but they may be associated with adverse drug reactions (ADRs). Objective To identify the ADRs associated with the use of biological drugs in Colombia. Methods This was a retrospective study of ADR reports from 2014 to 2019, contained in the database of Audifarma SA pharmacovigilance program. The ADRs, groups of associated drugs, and affected organs were classified. Results In total, 5,415 reports ...
Tópico(s): Biosimilars and Bioanalytical Methods
2020 - Public Library of Science | PLoS ONE
Leah Bakely, Catalina Correa-Salazar, Gudelia Rangel, Jesús Eduardo González-Fagoaga, Ahmed Ali Asadi González, Emilio A. Parrado, Fernando Riosmena, Ana P. Martínez-Donate,
Migration, detention, and deportation are often rife with violence. This study sought to examine associations between pre-migration experiences, detention conditions, and mental health among Mexicans deported from the U.S. to Mexico between 2020 and 2021. Data from the Migrante Project (N=306, weighted N=14,841) were analyzed using descriptive statistics and unadjusted and adjusted multivariate regression models. The prevalence of a lifetime mental health diagnosis was 18.5%. Exposure to adverse ...
Tópico(s): Racial and Ethnic Identity Research
2023 - Johns Hopkins University Press | Journal of Health Care for the Poor and Underserved
Gonzalo Parrado-Hernando, Antun Pfeifer, Fernando Frechoso, Luis Miguel, Neven Duić,
The Spanish national energy and climate plan (PNIEC) has recently been published, leading the worldwide task of climate change mitigation towards a net zero-carbon economy by 2050. The objective scenario of the PNIEC expects to reach a renewable share in the power system of 74% by 2030. In this context, three contributions are developed: i) providing an analysis of how Spain is facing the energy transition; ii) conceptualizing the link between an hourly energy model (EnergyPLAN) and a yearly integrated ...
Tópico(s): Building Energy and Comfort Optimization
2022 - Elsevier BV | Energy
Mirna Hilal, María F. Parrado, Mariana Rosa, Miriam Gallardo, Luis V. Orce, Eddy M. Massa, Juan Antonio González, Fernando E. Prado,
UV-B radiation (280-320 nm) is harmful to living organisms and has detrimental effects on plant growth, development and physiology. In this work we examined some mechanisms involved in plant responses to UV-B radiation. Seedlings of quinoa (Chenopodium quinoa Willd.) were exposed to variable numbers of UV-B radiation doses, and the effect on cotyledons was studied. We analyzed (1) cotyledons anatomy and chloroplasts ultrastructure; (2) peroxidase activity involved in the lignification processes; and ( ...
Tópico(s): Seed and Plant Biochemistry
2004 - Wiley | Photochemistry and Photobiology
Mirna Hilal, María F. Parrado, Mariana Rosa, Miriam Gallardo, Luis V. Orce, Eddy M. Massa, Juan Antonio González, Fernando E. Prado,
ABSTRACT UV‐B radiation (280–320 nm) is harmful to living organisms and has detrimental effects on plant growth, development and physiology. In this work we examined some mechanisms involved in plant responses to UV‐B radiation. Seedlings of quinoa ( Chenopodium quinoa Willd.) were exposed to variable numbers of UV‐B radiation doses, and the effect on cotyledons was studied. We analyzed ( 1 ) cotyledons anatomy and chloroplasts ultrastructure; ( 2 ) peroxidase activity involved in the lignification processes; ...
Tópico(s): Seed and Plant Biochemistry
2004 - Wiley | Photochemistry and Photobiology
Gonzalo Parrado-Hernando, Fernando Frechoso, Luis Miguel,
Tópico(s): Advanced Power Generation Technologies
2024 - SDEWES Centre | Journal of Sustainable Development of Energy Water and Environment Systems
Manuel Enrique Machado‐Duque, Jorge Enrique Machado‐Alba, Andrés Gaviria‐Mendoza, Luis Fernando Valladales‐Restrepo, Ilsa Yadira Parrado-Fajardo, Mauren Ospina-Castellanos, Luisa Fernanda Rojas-Chavarro, John Alexander López-Rincón,
Introducción. El uso de medicamentos puede conllevar errores de medicación que desemboquen en la hospitalización del paciente, el aumento de los costos relacionados con la atención e, incluso, la muerte.Objetivos. Determinar la prevalencia de errores de medicación notificados en un sistema de información de farmacovigilancia en Colombia entre el 2018 y el 2019.Materiales y métodos. Se hizo un estudio observacional a partir del registro de errores de medicación de un sistema de farmacovigilancia ...
Tópico(s): Quality and Safety in Healthcare
2021 - National Institute of Health | Biomédica
Produção Nacional
Revisado por pares
Ronald E. Blanton, Luciano Kalabric Silva, Vanessa G Morato, Antonio Parrado, Juarez Pereira Dias, Paulo Roberto Santana de Melo, Eliana Almeida Gomes Reis, Katrina A.B. Goddard, Márcio Roberto Teixeira Nunes, Sueli Guerreiro Rodrigues, Pedro Fernando da Costa Vasconcelos, Jesuina M Castro, Mitermayer Galvão dos Reis, Maurício L. Barreto, Maria Glória Teixeira,
To test whether African ancestry is protective for severe dengue, we genotyped 49 hospitalized cases of dengue hemorrhagic fever (DHF) as well as 293 neighborhood cases of dengue fever and 294 asymptomatic controls in Salvador, Bahia, Brazil. Ancestry-informative markers and 282 unlinked SNPs not associated with the clinical presentation of dengue were used to estimate ancestry. After controlling for income, both self-defined Afro-Brazilian ethnicity and African ancestry were protective for DHF (P= ...
Tópico(s): Vector-Borne Animal Diseases
2008 - Springer Nature | European Journal of Human Genetics
Gonzalo Parrado-Hernando, Luka Herc, Antun Pfeifer, Iñigo Capellán‐Pérez, Ilija Batas Bjelić, Neven Duić, Fernando Frechoso, Luis Miguel, Vladimir Z. Gjorgievski,
Long term-energy planning has gradually moved towards finer temporal and spatial resolutions of the energy system to design the decarbonization of the society. However, integrated assessment models (IAMs), focusing on a broader concept of sustainability transition, are typically yearly-resolution models which complicates capturing the specific supply-demand dynamics, relevant in the transition towards renewable energy sources (RES). Different methods for introducing sub-annual information are being ...
Tópico(s): Atmospheric and Environmental Gas Dynamics
2022 - Elsevier BV | Renewable Energy
Álvaro Parrado, Fernando Costa Klauk, Marília Macorin de Azevedo, Paulo Roberto Prado Constantino,
Este estudo apresenta um retrato do atendimento à pessoa com deficiência (PcD) nas Escolas Técnicas Estaduais do Centro Estadual de Educação Tecnológica Paula Souza (CEETEPS) no ano de 2023, enfatizando o quantitativo do atendimento educacional especializado (AEE) e a construção desses dados. O objetivo é analisar a representatividade dos alunos público-alvo da educação especial nas matrículas das escolas técnicas do CEETEPS, investigando os processos de produção dos indicadores de demanda e as práticas ...
Tópico(s): Social and Political Issues
2024 - Servicios Academicos Intercontinentales | DELOS Desarrollo Local Sostenible
... 13, 1972, at the age of 19 years, Fernando “Nando” Parrado was travelling to Chile. While flying over the ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2009 - Elsevier BV | The Lancet Neurology
Cristián Arredondo, Carolina Cefaliello, Agnieszka Dyrda, Nur Jury, Pablo Martínez, Iván Darío Parrado Díaz, Armando Amaro, Hélène Tran, Danna Morales, Marı́a Pertusa, Lorelei Stoica, Elsa Fritz, Daniela Corvalán, Sebastián Abarzúa, Maxs Méndez-Ruette, Paola Fernández, Fabiola Rojas, Meenakshi Sundaram Kumar, Rodrigo Aguilar, Sandra Almeida, Alexandra Weiss, Fernando J. Bustos, Fernando D. González‐Nilo, Carolina Otero, María Florencia Tevy, Daryl A. Bosco, Juan C. Sáez, Thilo Kähne, Fen‐Biao Gao, James Berry, Katharine Nicholson, Miguel Sena‐Esteves, Rodolfo Madrid, Diego Varela, Martı́n Montecino, Robert H. Brown, Brigitte van Zundert,
Non-cell-autonomous mechanisms contribute to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), in which astrocytes release unidentified factors that are toxic to motoneurons (MNs). We report here that mouse and patient iPSC-derived astrocytes with diverse ALS/FTD-linked mutations (SOD1, TARDBP, and C9ORF72) display elevated levels of intracellular inorganic polyphosphate (polyP), a ubiquitous, negatively charged biopolymer. PolyP levels are also ...
Tópico(s): biodegradable polymer synthesis and properties
2022 - Cell Press | Neuron
Santiago Alfayate Miguélez, Genoveva Yagüe Guirao, Ana Ruiz, Manuel Sánchez‐Solís, Mirian Domenech Lucas, Fernando González‐Camacho, María del Mar Ortiz Romero, Pilar Espejo García, C. Guerrero Gómez, Antonio Iofrío de Arce, Laura Moreno Parrado, Rosa Sánchez Andrada, Eva Cascales Alcolea, Sebastián Lorente García, Pedro Paredes Reyes, Ángela Casquet Barceló, M. López Yepes, Juan Vigueras Abellán, Gonzalo Sanz Mateo,
Background: An epidemiological study of Streptococcus pneumoniae nasopharyngeal carriage in healthy children was carried out five years after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13). Objectives: Study the impact of pediatric vaccination with PCV13, and other associated epidemiological factors on the status of nasopharyngeal carriage, the circulating pneumococcal serotypes, and the antibiotic susceptibility to more frequently used antibiotics. Methods: A multi-center ...
Tópico(s): Respiratory viral infections research
2020 - Multidisciplinary Digital Publishing Institute | Vaccines
Jordi Solé, Roger Samsó, Emilio Garcı́a-Ladona, Antonio Garcı́a-Olivares, Joaquim Ballabrera‐Poy, Teresa Madurell, Antonio Turiel, Oleg Osychenko, Darío Álvarez Álvarez, Ugo Bardi, Martin Baumann, Kat Buchmann, Iñigo Capellán‐Pérez, Martin Černý, Óscar Carpintero, Ignacio de Blas, Carlos de Castro, J.-D. De Lathouwer, Carmen Duce, Lukas Eggler, Javier Enriquez, Sara Falsini, Kuishuang Feng, N. Ferreras, Fernando Frechoso, Klaus Hubacek, Aled Jones, R. Kaclíková, Christian Kerschner, Christian Kimmich, Luis Fernando Lobejón, Pedro L. Lomas, Gianluca Martelloni, Margarita Mediavilla, Luis Miguel, Davide Natalini, Jaime Nieto, Angel Nikolaev, G. Parrado, Stavroula Papagianni, Ilaria Perissi, C. Ploiner, Lulin Radulov, Paula Rodrigo, Laixiang Sun, M. Theofilidi,
This paper reviews different approaches to modelling the energy transition towards a zero carbon economy. It identifies a number of limitations in current approaches such as a lack of consideration of out-of-equilibrium situations (like an energy transition) and non-linear feedbacks. To tackle those issues, the new open source integrated assessment model pymedeas is introduced, which allows the exploration of the design and planning of appropriate strategies and policies for decarbonizing the energy ...
Tópico(s): Environmental Impact and Sustainability
2020 - Elsevier BV | Renewable and Sustainable Energy Reviews
Gonzalo Parrado-Hernando, Luis Miguel, Fernando Frechoso,
The development of renewable energies has been highlighted as a driver of the energy transition towards a more sustainable society. Despite the well-known benefits in health and regional energy resilience when those sources are leveraged, wind- and solar-based technologies bring about flexibility challenges in the power system. The variability in the generation of energy from renewable sources is probably its greatest weakness. This problem can be alleviated in different ways, but a detailed statistical ...
Tópico(s): Hybrid Renewable Energy Systems
2021 - National University of Colombia | DYNA
Juan Fernando Cano, María Pilar Fumanal, Carlos Ferrer, Juan Usera, Ana María Blázquez Morilla, Jesús María Parrado del Olmo,
Tópico(s): Geological and Geophysical Studies Worldwide
1999 - Elsevier BV | Zeitschrift für Geomorphologie
Magdalena Caminoa, M.F. Martín‐Muñoz, Fernando Pineda de la Losa, G. García-Parrado García, Irina Bobolea, Jesús Nicolás Larco Coloma, José Maria Díaz‐Pena, Santiago Quirce,
RATIONALE: Food allergy is a rare affection among breastfed children. Although cow's milk is the most important causative allergen, any other food allergen may be responsible for allergic reactions at that age. The aim of our study was to identify breast milk allergens involved in allergic reactions after breastfeeding. METHODS: We report on 5 children who developed urticaria or gastrointestinal symptoms after breastfeeding. Prick tests with breast milk, cow's milk, white egg and the foods ingested ...
Tópico(s): Eosinophilic Esophagitis
2010 - Elsevier BV | Journal of Allergy and Clinical Immunology
Povedano Eloy, H Cincotto Fernando, Parrado Concepcion, Diez Paula, Sanchez Alfredo, C Canevari Thiago, A S Machado Sergio, M Pingarron Jose, Villalonga Reynaldo,
2017 - Elsevier BV | Biosensors and Bioelectronics
Johanna Fernández, Oscar Fernando Gómez Morales,
En el presente artículo se realizó un análisis de la situación actual de la práctica del turismo de naturaleza en la Reserva Forestal Protectora quebrada Honda y caños Parrado y Buque, mediante un levantamiento de los principales atractivos turísticos, la elaboración de un mapa temático de conflicto con el uso del suelo y la práctica del turismo, y un análisis de la situación actual de la reserva a través de la matriz DOFA . Como resultados se encontró que el tipo de turismo de naturaleza que se practica ...
Tópico(s): Finance, Taxation, and Governance
2022 - Universidad Externado de Colombia | Turismo y Sociedad
Pablo Monedero, Alfredo Gea, Pedro Castro, Ángel M. Candela-Toha, María L. Hernández-Sanz, Egoitz Arruti, Jesús Villar, Carlos Ferrando, Pablo Monedero, Alfredo Gea, Pedro Castro, Ángel M. Candela-Toha, Marina Vendrell, G. Sánchez‐Etayo, Amalia Alcón, Isabel Belda, Mercè Agustí, Albert Carramiñana, Isabel Gracia, Miriam Panzeri, Irene León, Jaume Balust, Ricard Navarro, M.J. Arguís, María José Carretero, Cristina Ibáñez, Juan Perdomo, Antonio Rezusta López, Manuel López-Baamonde, Tomás Cuñat, Marta Ubré, Antonio Ojeda, Andrea Calvo, Eva Rivas, Paola Hurtado, Roger Pujol, Nuria Hinarejos Martín, J. Tercero, Pepe Sanahuja, Marta Magaldi, Miquel Coca‐Martinez, Elena del Río, Julia Martínez-Ocón, Paula Masgoret, Monserrat Tió, A. Caballero, Raquel Risco, R. Bergé, Lidia Díaz Gómez, Nicolás de Riva, Ana Ruiz, Beatriz Beatriz, Tena, Sebastián Jaramillo, José M. Balibrea, Francisco B. de Lacy, Ana Otero, Ainitze Ibarzábal, Raquel Bravo, Anna Carreras-Castañer, Daniel Martín-Barreda, Alfonso Jesús Alias, Mariano Balaguer-Castro, Jorge Aliaga, Alex Almuedo-Riera, Joan Ramón Alonso, Rut Andrea, Gerard Sergi Angelès, Marilyn Arias, Fátima Aziz, Joan R. Badia, Enric Barbeta, Toni Torres, Guillem Batiste, Pau Benet, X. Borrat, María Borrell, Ernest Bragulat, Inmaculada Carmona, Manuel Castellá, Pedro Castro, Joan Ceravalls, Óscar Comino, Claudia Cucciniello, Clàudia De Deray, O De Diego, Paula De la Matta, Marta Farrero, Javier Fernández, Sara Fernández, Anna Fernández, Miquel Ferrer, Ana Fervienza, María Tallo Forga, Daniel Forné, C Redondo Galán, Andrea Gómez, Eduard Guasch, Maria De Santis, Adriana Jacas, Beltrán Jiménez, Pere Leyes, Teresa López, José Antonio Martínez, Graciela Martínez‐Palli, Jordi Mercadal, Guido Muñoz, José Luís Bernal Muñoz, Ricard Navarro, Josep M. Nicolás, Jose T. Ortiz‐Pérez, Anna Peiró, Manuel Avelino Pestano Pérez, Esteban Poch, M Pujol, Eduard Quintana, Bartomeu Ramis, Enric Reverter, Irene Rovira, Pablo Ruiz, Elena Sandoval, Stefan Schneider, Oriol Sibila, Carla Solé, Álex Soriano, Dolors Soy, M. Suárez, Adrián Téllez, David Toapanta, Antoni Torres, Xavier Urra, César Aldecoa, Alicia Bordell, Silvia Martín, Judith Andrés, A. Martínez Ruíz, Gonzalo Tamayo, Iñaki Bilbao Villasante, F. Iturri Clavero, Covadonga Peralta Álvarez, Julia T. Herrera Díez, Andrea García Trancho, Iñaki Sainz Mandiola, Carmen Suárez, Angela Ruiz Bocos, Eneritz Urrutia Izagirre, Pablo Ortiz de Urbina Fernández, Naiara Apodaka López, Leire Prieto Molano, Eunate Ganuza Martínez, Iratxe Vallinas Hidalgo, Karmele de Orte Sancho, Celia González Paniagua, Gemma Ortiz Labrador, Mireia Pérez Larrañaga, Marta López Miguelez, Estíbaliz Bárcena Andrés, Erik Urutxurtu Laureano, María Jesús Maroño Boedo, Blanca Escontrela Rodríguez, Aitziber Ereñozaga Camiruaga, Deiene Lasuen Aguirre, Ainhoa Zabal Maeztu, Ane Guereca Gala, Iker Castelo Korro, Andrés Álvarez Campo, Alejandro Carcelen Viana, Alejandro Alberdi Enríquez, Xabier Ormazábal Rementeria, Alberto Sánchez, Rosa Gutiérrez Rico, Pablo Barbier Damborenea, Marta Guerenabarrena Momeñe, Borja Cuesta Ruiz, Alejandro López Rico, Ana Rojo Polo, Covadonga García Grijelmo, Mikel Celorrio Reta, Eneko Martín Arroyo, Leire Artaza Aparicio, Iñaki Ituarte Aspiazu, Ane Igeregi Basabe, Itxaso Merino Julian, I. Rico, María Paz Martínez, Ramón Adalia Bartolomé, Luigi Zattera, Irina Adalid Hernández, Leire Larrañaga Altuna, Aina Serrallonga Castells, Adriana Vílchez Garcia, María Angélica Rivera Núñez, Lorena Román, Isabel Delgado, Adela Benítez-Cano Martínez, Mireia Chanzá Albert, Juan Carlos Álvarez García, Luis Aguilera Cuchillo, Sandra Beltrán de Heredia, Jesús Carazo Cordobés, Carlos Alberto García Bernedo, Fernando Escolano Villén, Francisco Javier Redondo Calvo, Rubén Villazala González, Víctor Baladrón González, Patricia Faba, Omar Montenegro, Natalia Bejarano, Sergio Marcos Contreras, Alejandro García Rodríguez, Saleta Rey Vázquez, Cristina García Pérez, E. Miguélez, Irene Pérez Blanco, David García Rivera, Ane Martín de la Fuente, Marta Pardo, Vanessa Rodríguez, U. Bengoetxea, F. Ramasco, Sheila Olga Santidrián Bernal, Alvar Santa Cruz Hernando, A. Planas Roca, Carlos Figueroa Yusta, Esther García Villabona, Carmen Vallejo Lantero, Eva Patiño Rodriguez, Alvaro Esquivel Toledo, David Arribas Méndez, Mar Orts Rodriguez, Rosa Méndez Hernández, Jesús Nieves Alonso, Inés Imaz Artazcoz, Sonia Expósito Carazo, Carlos Román Guerrero, Elena Rojo Rodríguez, Ricardo Moreno González, Julia Hernando Santos, Jara Torrente Pérez, Esperanza Mata Mena, Manuel Martı́nez, Enrique Alday Muñoz, Patricia Martín Serrano, Laura Cotter Muñoz, Amadea Mjertan, Diego Gutiérrez Martínez, Carmen Rodríguez García, Olaya Alonso Viejo, Juan Alvarez Pereira, Ana Carmona Bonet, Diana Parrado López, Eva de Dios Tomas, R. Martín Celemín, María Luisa Meilan Paz, Luis Quecedo Gutiérrez, Noemí Diaz Velasco, Gabriel Martin Hernández, Francisco Garcia del Corral, Gloria Hernandez Arias, David Cuesta, Ana Gómez Rice, Encarna Mateos Sevillano, Natalia Olmos Molpeceres, Beatriz Domínguez, Ana Vázquez Lima, A Candela, Ismael A. Acevedo Bambaren, Maria Isabel Albala Blanco, Paloma Alonso Montoiro, Fernando Álvarez Utrera, Juan Avellanosa Esteruelas, Amal Azzam López, Alberto José Balvis Balvis, Tommaso Bardi, María Beltrán Martín, Jacobo Benatar Haserfaty, Alberto Berruezo Camacho, Laura Betolaza Weimer, María del Mar Carbonell Soto, Cristina Seral, Cristina Cerro Zaballos, Elizabeth Claros Llamas, Pilar Coleta Orduna, Ingrid P. Cortes Forero, Pascual Agustín Crespo Aliseda, María Angélica de Pablo Pajares, Yolanda Díez Remesal, Trinidad Dorado Díaz, Noemí Echevarría Blasco, María Elena Elías Martín, Javier Felices Triviño, Natalia Fernández López, Cristina Fernández Martín, Natalia Ferreiro Pozuelo, Luis Gajate Martín, Clara Gallego Santos,
Abstract Background Critically ill patients with coronavirus disease 19 (COVID-19) have a high fatality rate likely due to a dysregulated immune response. Corticosteroids could attenuate this inappropriate response, although there are still some concerns regarding its use, timing, and dose. Methods This is a nationwide, prospective, multicenter, observational, cohort study in critically ill adult patients with COVID-19 admitted into Intensive Care Units (ICU) in Spain from 12th March to 29th June ...
BioMed Central
Carlos Ferrando, Ricard Mellado‐Artigas, Alfredo Gea, Egoitz Arruti, César Aldecoa, R. Adàlia, F. Ramasco, Pablo Monedero, Emilio Maseda, Gonzalo Tamayo, María L. Hernández-Sanz, Jordi Mercadal, Ascensión Martín-Grande, Robert M. Kacmarek, Jesús Villar, Fernando Suárez-Sipmann, Marina Vendrell, G. Sánchez‐Etayo, Amalia Alcón, Isabel Belda, Mercè Agustí, Albert Carramiñana, Isabel Gracia, Miriam Panzeri, Irene León, Jaume Balust, Ricard Navarro, M.J. Arguís, María José Carretero, Cristina Ibáñez, Juan Perdomo, Antonio Rezusta López, Manuel López-Baamonde, Tomás Cuñat, Marta Ubré, Antonio Ojeda, Andrea Calvo, Eva Rivas, Paola Hurtado, Roger Pujol, Nuria Hinarejos Martín, J. Tercero, Pepe Sanahuja, Marta Magaldi, Miquel Coca‐Martinez, Elena del Río, Julia Martínez-Ocón, Paula Masgoret, A. Caballero, Raquel Risco, Lidia Díaz Gómez, Nicolás de Riva, Ana Ruiz, Beatriz Tena, Monserrat Tió, Sebastián Jaramillo, José M. Balibrea, Francisco B. de Lacy, Ana Otero, Ainitze Ibarzábal, Raquel Gómez Bravo, Anna Carreras-Castañer, Daniel Martín-Barreda, Alfonso Jesús Alias, Mariano Balaguer-Castro, Jorge Aliaga, Alex Almuedo-Riera, Joan Ramón Alonso, Rut Andrea, Gerard Sergi Angelès, Marilyn Arias, Fátima Aziz, Joan R. Badia, Enric Barbeta, Toni Torres, Guillem Batiste, Pau Benet, X. Borrat, María Borrell, Ernest Bragulat, Inmaculada Carmona, Manuel Castellá, Pedro Castro, Joan Ceravalls, Óscar Comino, Claudia Cucciniello, Clàudia De Deray, O De Diego, Paula De la Matta, Marta Farrero, Javier Fernández, Sara Fernández, Anna Fernández, Miquel Ferrer, Ana Fervienza, María Tallo Forga, Daniel Forné, C Redondo Galán, Andrea Gómez, Eduard Guasch, María Hernández Tejero, Adriana Jacas, Beltrán Jiménez, Pere Leyes, Teresa López, José Antonio Martínez, Graciela Martínez‐Palli, Jordi Mercadal, Guido Muñoz, José Luís Bernal Muñoz, Josep M. Nicolás, Jose T. Ortiz‐Pérez, Anna Peiró, Manuel Avelino Pestano Pérez, Esteban Poch, M Pujol, Eduard Quintana, Bartomeu Ramis, Enric Reverter, Irene Rovira, Pablo Ruiz, Elena Sandoval, Stefan Schneider, Oriol Sibila, Carla Solé, Álex Soriano, Dolors Soy, M. Suárez, Adrián Téllez, David Toapanta, Antoní Torres, Xavier Urra, César Aldecoa, Alicia Bordell, Silvia Martín, Judith Andrés, A. Martínez Ruíz, Gonzalo Tamayo, Iñaki Bilbao Villasante, F. Iturri Clavero, Covadonga Peralta Álvarez, Julia T. Herrera Díez, Andrea García Trancho, Iñaki Sainz Mandiola, Carmen Suárez, Angela Ruiz Bocos, Eneritz Urrutia Izagirre, Pablo Ortiz de Urbina Fernández, Naiara Apodaka López, Leire Prieto Molano, Eunate Ganuza Martínez, Iratxe Vallinas Hidalgo, Karmele de Orte Sancho, Celia González Paniagua, Gemma Ortiz Labrador, Mireia Pérez Larrañaga, Marta López Miguelez, Estíbaliz Bárcena Andrés, Erik Urutxurtu Laureano, María Jesús Maroño Boedo, Blanca Escontrela Rodríguez, Aitziber Ereñozaga Camiruaga, Deiene Lasuen Aguirre, Ainhoa Zabal Maeztu, Ane Guereca Gala, Iker Castelo Korro, Andrés Álvarez Campo, Alejandro Carcelen Viana, Alejandro Alberdi Enríquez, Xabier Ormazábal Rementeria, Alberto Sánchez, Rosa Gutiérrez Rico, Pablo Barbier Damborenea, Marta Guerenabarrena Momeñe, Borja Cuesta Ruiz, Alejandro López Rico, Ana Rojo Polo, Covadonga García Grijelmo, Mikel Celorrio Reta, Eneko Martín Arroyo, Leire Artaza Aparicio, Iñaki Ituarte Aspiazu, Ane Igeregi Basabe, Itxaso Merino Julian, I. Rico, María Paz Martínez, R. Adàlia, Luigi Zattera, Irina Adalid Hernández, Leire Larrañaga Altuna, Aina Serrallonga Castells, Adriana Vílchez Garcia, María Angélica Rivera Núñez, Lorena Román, Francisco Javier Redondo Calvo, Rubén Villazala González, Víctor Baladrón González, Patricia Faba, Omar Montenegro, Natalia Bejarano, Sergio Marcos Contreras, Alejandro García Rodríguez, Saleta Rey Vázquez, Cristina García Pérez, E. Miguélez, Irene Pérez Blanco, David García Rivera, Ane Martín de la Fuente, Marta Pardo, Vanessa Rodríguez, U. Bengoetxea, F. Ramasco, Sheila Olga Santidrián Bernal, Alvar Santa Cruz Hernando, A. Planas Roca, Carlos Figueroa Yusta, Esther García Villabona, Carmen Vallejo Lantero, Eva Patiño Rodriguez, Alvaro Esquivel Toledo, David Arribas Méndez, Mar Orts Rodriguez, Rosa Méndez Hernández, Jesús Nieves Alonso, Inés Imaz Artazcoz, Sonia Expósito Carazo, Carlos Román Guerrero, Elena Rojo Rodríguez, Ricardo Moreno González, Julia Hernando Santos, Jara Torrente Pérez, Esperanza Mata Mena, Manuel Martı́nez, Enrique Alday Muñoz, Patricia Martín Serrano, Laura Cotter Muñoz, Amadea Mjertan, Diego Gutiérrez Martínez, Carmen Rodríguez García, Olaya Alonso Viejo, Juan Alvarez Pereira, Ana Carmona Bonet, Diana Parrado López, Eva de Dios Tomas, R. Martín Celemín, María Luisa Meilan Paz, Luis Quecedo Gutiérrez, Noemí Diaz Velasco, Gabriel Martin Hernández, Francisco Garcia del Corral, Gloria Hernandez Arias, David Cuesta, Ana Gómez Rice, Encarna Mateos Sevillano, Natalia Olmos Molpeceres, Beatriz Domínguez, Ana Vázquez Lima, A Candela, Ismael A. Acevedo Bambaren, Maria Isabel Albala Blanco, Paloma Alonso Montoiro, Fernando Álvarez Utrera, Juan Avellanosa Esteruelas, Amal Azzam López, Alberto José Balvis Balvis, Tommaso Bardi, María Beltrán Martín, Jacobo Benatar Haserfaty, Alberto Berruezo Camacho, Laura Betolaza Weimer, María del Mar Carbonell Soto, Cristina Seral, Cristina Cerro Zaballos, Elizabeth Claros Llamas, Pilar Coleta Orduna, Ingrid P. Cortes Forero, Pascual Agustín Crespo Aliseda, María Angélica de Pablo Pajares, Yolanda Díez Remesal, Trinidad Dorado Díaz, Noemí Echevarría Blasco, María Elena Elías Martín, Javier Felices Triviño, Natalia Fernández López, Cristina Fernández Martín, Natalia Ferreiro Pozuelo, Luis Gajate Martín, Clara Gallego Santos, Diego Gil Mayo, María Gómez Rojo, Claudia González Cibrián, Elena Herrera López, Borja Hinojal Olmedillo, Berta Iglesias Gallego, Sassan Khonsari, María Nuria Mane Ruiz,
Abstract Background Awake prone positioning (awake-PP) in non-intubated coronavirus disease 2019 (COVID-19) patients could avoid endotracheal intubation, reduce the use of critical care resources, and improve survival. We aimed to examine whether the combination of high-flow nasal oxygen therapy (HFNO) with awake-PP prevents the need for intubation when compared to HFNO alone. Methods Prospective, multicenter, adjusted observational cohort study in consecutive COVID-19 patients with acute respiratory ...
BioMed Central
Alessandro Gialluisi, Mafalda Giovanna Reccia, Nicola Modugno, Teresa Nutile, Alessia Lombardi, Luca Giovanni Di Giovannantonio, Sara Pietracupa, Daniela Ruggiero, Simona Scala, Stefano Gambardella, Alastair Noyce, Rauan Kaiyrzhanov, Ben Middlehurst, Demis A. Kia, Manuela Tan, Henry Houlden, Huw R. Morris, Hélène Plun‐Favreau, Peter Holmans, John Hardy, Daniah Trabzuni, John P. Quinn, Vivien J. Bubb, Kin Y. Mok, Kerri J. Kinghorn, Kimberley Billingsley, Nicholas Wood, Patrick A. Lewis, Sebastian R. Schreglmann, Ruth C. Lovering, Lea R’Bibo, Claudia Manzoni, Mie Rizig, Mina Ryten, Sebastian Guelfi, Valentina Escott‐Price, Viorica Chelban, Thomas Foltynie, Nigel Williams, Karen Morrison, Carl E Clarke, Alexis Brice, Alexis Brice, Suzanne Lesage, Jean‐Christophe Corvol, María Martínez, Claudia Schulte, Kathrin Brockmann, Javier Simón‐Sánchez, Peter Heutink, Patrizia Rizzu, Manu Sharma, Thomas Gasser, Mark Cookson, Sara Bandrés‐Ciga, Cornelis Blauwendraat, David W. Craig, Derek P. Narendra, Faraz Faghri, J. Raphael Gibbs, Dena Hernández, Kendall Van Keuren‐Jensen, Joshua Shulman, Hirotaka Iwaki, Hampton L. Leonard, Mike A. Nalls, Laurie Robak, José Brás, Rita Guerreiro, Steven Lubbe, Steven Finkbeiner, Niccolò E. Mencacci, Codrin Lungu, Andrew Singleton, Sonja W. Scholz, Xylena Reed, Roy N. Alcalay, Ziv Gan‐Or, Guy A. Rouleau, Lynne Krohn, Lynne Krohn, Jacobus J. van Hilten, Johan Marinus, Astrid Adarmes‐Gómez, Miquel Aguilar, Ignacio Álvarez, Victoria Álvarez, Francisco Javier Barrero, Jesús Alberto Bergareche Yarza, Inmaculada Bernal‐Bernal, Marta Blázquez Estrada, Marta Bonilla‐Toribio, Juan A. Botía, María Teresa Boungiorno, Dolores Buiza‐Rueda, Fátima Carrillo, Mario Carrión‐Claro, Debora Cerdan, Jordi Clarimón, Yaroslau Compta, Mónica Díez-Fairén, Oriol Dols‐Icardo, Jacinto Duarte, Raquel Durán, Francisco Escamilla‐Sevilla, Mario Ezquerra, Cici Feliz, Manel Fernández, Rubén Fernández‐Santiago, Ciara García, Pedro Ruiz, Pilar Gómez‐Garre, María José Gómez Heredia, Isabel González Aramburu, Ana Gorostidi Pagola, Janet Hoenicka, Jon Infante, Silvia Jesús, Adriano Jiménez‐Escrig, Jaime Kulisevsky, Miguel A. Labrador‐Espinosa, José Luis López-Sendón, Adolfo López de Munaín Arregui, Daniel Macías, Irene Martínez‐Torres, Juan Marín‐Lahoz, Marı́a José Martı́, Juan Carlos Martínez‐Castrillo, Carlota Méndez‐del‐Barrio, Manuel Menéndez‐González, Marina Mata, Adolfo Mínguez‐Castellanos, Pablo Mir, Elisabet Mondragón Rezola, Esteban Muñoz, Javier Pagonabarraga, Pau Pástor, Francisco Pérez Errazquin, María Teresa Periñán, Javier Ruiz‐Martínez, Clara Ruz, A Rodríguez, María Sierra, Esther Suárez-Sanmartín, César Tabernero, Juan Pablo Tartari, Cristina Tejera‐Parrado, Eduard Tolosa, Francesc Valldeoriola, Laura Vargas‐González, Lydia Vela, Francisco Vives, Alexander Zimprich, Lasse Pihlstrøm, Mathias Toft, Sulev Kõks, Pille Taba, Sharon Hassin‐Baer, Kari Majamaa, Ari Siitonen, Njideka Okubadejo, Oluwadamilola O. Ojo, Rauan Kaiyrzhanov, Chingiz Shashkin, Nazira Zharkynbekova, Vadim Akhmetzhanov, Akbota Aitkulova, Elena Zholdybayeva, Zharkyn Jarmukhanov, Gulnaz Kaishybayeva, Altynay Karimova, Dinara Sadykova, Licia Iacoviello, Fernando Gianfrancesco, Dario Acampora, Maurizio D’Esposito, Antonio Simeone, Marina Ciullo, Teresa Esposito,
Abstract Background Parkinson’s disease (PD) is a neurodegenerative movement disorder affecting 1–5% of the general population for which neither effective cure nor early diagnostic tools are available that could tackle the pathology in the early phase. Here we report a multi-stage procedure to identify candidate genes likely involved in the etiopathogenesis of PD. Methods The study includes a discovery stage based on the analysis of whole exome data from 26 dominant late onset PD families, a validation ...
Tópico(s): RNA regulation and disease
2021 - BioMed Central | Molecular Neurodegeneration
Carmen Peláez-Moreno, Emilio Parrado-Hernández, Ascensión Gallardo-Antolín, Adrián Zambrano-Miranda, Fernando Díaz-de-María,
Voice over IP (VoIP) is becoming very popular due to the huge range of services that can be implemented by integrating different media (voice, audio, data, etc.). Besides, voice-enabled interfaces for those services are being very actively researched. Nevertheless the impoverishment of voice quality due to packet losses severely affects the speech recognizers supporting those interfaces ([8]). In this paper, we have compared the usual lost packets reconstruction method with an SVM-based one that outperforms ...
Tópico(s): Advanced Data Compression Techniques
2002 - Springer Science+Business Media | Lecture notes in computer science