... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Felipe Osório Costa, Eduardo Bortoluzzi Dornelles, Maria Fernanda Mânica-Cattani, Thaís Doeler Algarve, Olmiro Cezimbra de Souza Filho, Michele Rorato Sagrillo, Luiz Filipe Machado Garcia, Ivana Beatrice Mânica da Cruz,
This study investigated the in-vitro antioxidant properties of the ovulation induction drug, clomiphene citrate, and assessed whether its effects are influenced by the Val16Ala polymorphism in the SOD2 gene, which encodes manganese superoxide dismutase enzyme. The investigation involved an in-vitro experimental protocol testing the effect of different concentrations of clomiphene citrate on antioxidant capacity, reactive oxygen species (ROS) production and peripheral blood mononuclear cell (PBMC) ...
Tópico(s): Estrogen and related hormone effects
2012 - Elsevier BV | Reproductive BioMedicine Online
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Aline Augusti Boligon, Michele Rorato Sagrillo, Luiz Filipe Machado, Olmiro De Souza Filho, Michel Mansur Machado, Ivana Beatrice Mânica da Cruz, Margareth Linde Athayde,
Flavonoids are claimed to protect against cardiovascular disease, certain forms of cancer and ageing, possibly by preventing initial DNA damage. Therefore, we investigated the protective effects of crude extract, ethyl acetate fraction and flavonoids (quercetin, quercitrin, isoquercitrin and rutin) isolated from the leaves from Scutia buxifolia against chromosome damage induced by H2O2 in human lymphocytes by analyzing cellular growth rate, cell viability, mitotic index and chromosomal instability. ...
Tópico(s): Morinda citrifolia extract uses
2012 - Multidisciplinary Digital Publishing Institute | Molecules
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Michele Rorato Sagrillo, Luiz Filipe Machado Garcia, Olmiro Cezimbra de Souza Filho, Marta Maria Medeiros Frescura Duarte, Euler Esteves Ribeiro, Francine Carla Cadoná, Ivana Beatrice Mânica da Cruz,
This study quantifies the bioactive molecules in and determines the in vitro protective effect of ethanolic extracts isolated from the peel and pulp of tucumã (Astrocaryum aculeatum, Mart.), an Amazonian fruit rich in carotenoids. The cytoprotective effect of tucumã was evaluated in lymphocyte cultures exposed to H2O2 using spectrophotometric, fluorimetric, and immunoassay assays. The results confirmed that tucumã pulp extract is rich in β-carotene and quercetin, as previously described in the literature. ...
Tópico(s): Phytochemicals and Antioxidant Activities
2014 - Elsevier BV | Food Chemistry
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Romeo Lages Simões, Fernando Antônio Martins Bermudes, Hudson Silva Andrade, Filipe Machado Barcelos, Breno Pinheiro Rossoni, Gustavo Peixoto Soares Miguel, Carlos Alberto de Castro Fagundes, Gustavo Pereira Fraga,
to compare the knowledge of medical students between those who are members of the Trauma League (TL) and those from a non-Trauma League (NTL) group of the Federal University of Espírito Santo (UFES).cross-sectional, analytical and descriptive study. Two knowledge tests, with 30 questions each, were applied to students from 3rd to 12th period, randomly selecting five students per period, with 50 students in the TL group and 50 in NTL. The questionnaire topics were: pre-hospital care, the mnemonic ABCDE ...
Tópico(s): Pelvic and Acetabular Injuries
2014 - Brazilian College of Surgeons | Revista do Colégio Brasileiro de Cirurgiões
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Olmiro Cezimbra de Souza Filho, Michele Rorato Sagrillo, Luiz Filipe Machado Garcia, Alencar Kolinski Machado, Francine Carla Cadoná, Euler Esteves Ribeiro, Marta Maria Medeiros Frescura Duarte, Ademir F. Morel, Ivana Beatrice Mânica da Cruz,
Tucuma (Astrocaryum aculeatum) is an Amazonian fruit that presents high levels of carotenoids and other bioactive compounds such as quercetin. The extracts of tucuma peel and pulp present strong antioxidant activity which illustrate an elevated concentration that causes cytotoxic effects in human peripheral blood mononuclear cells (PBMCs). This study performed additional investigations to analyze the potential genotoxic effects of the tucuma extracts on PBMCs. The genotoxicity was evaluated by DNA ...
Tópico(s): Plant biochemistry and biosynthesis
2013 - Mary Ann Liebert, Inc. | Journal of Medicinal Food
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Micheli Lamberti Jobim, Roberto Christ Vianna Santos, Camilla Filippi dos Santos Alves, Raul Moreira Oliveira, Clarice Pinheiro Mostardeiro, Michele Rorato Sagrillo, Olmiro Cezimbra de Souza Filho, Luiz Filipe Machado Garcia, Maria Fernanda Mânica-Cattani, Euler Esteves Ribeiro, Ivana Beatrice Mânica da Cruz,
Several compounds present in fruits as polyphenols are able to kill or inhibit the growth of microorganisms. These proprieties are relevant mainly in tropical areas, as Amazonian region where infectious are highly prevalent. Therefore, this study investigated the antimicrobial activity of tucumã Amazonian fruit against 37 microorganisms. The potential role of oxidative metabolism imbalance was also studied as causal mechanism of antimicrobial activity. The results showed antibacterial effect of ...
Tópico(s): Bee Products Chemical Analysis
2013 - Elsevier BV | Microbiological Research
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Ivana Beatrice Mânica da Cruz, Antônio Lourenço Severo, Verônica Farina Azzolin, Luiz Filipe Machado Garcia, André Kühn, Osvandré Lech,
Advances in the studies with adult mesenchymal stem cells (MSCs) have turned tissue regenerative therapy into a promising tool in many areas of medicine. In orthopedics, one of the main challenges has been the regeneration of cartilage tissue, mainly in diarthroses. In the induction of the MSCs, in addition to cytodifferentiation, the microenvironmental context of the tissue to be regenerated and an appropriate spatial arrangement are extremely important factors. Furthermore, it is known that MSC ...
Tópico(s): Periodontal Regeneration and Treatments
2016 - Brazilian Society of Orthopedics and Traumatology | Revista Brasileira de Ortopedia (English Edition)
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII
Joaquim Carneiro, Filipe Machado, L. Rebouta, M. I. Vasilevskiy, Senen Lanceros-Méndez, V. Teixeira, Manuel F. M. Costa, A.P. Samantilleke,
The influence of O2 flow rate on the compositional, optical and electrical characteristics of silicon oxide (SiOx) thin films (x < 2) were studied in this work. The SiOx thin films were obtained by pulsed direct current (DC) magnetron sputtering (PMS) onto n-type Si wafers (and also on glass substrates) at a vacuum of 3 × 10−3 Pa. Rutherford backscattering spectrometry (RBS) was used to check the compositional elements of deposited films and its oxidized states were analysed via Fourier-transform infrared ( ...
Tópico(s): Semiconductor materials and devices
2019 - Multidisciplinary Digital Publishing Institute | Coatings
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII
Filipe Machado, Nelson Duarte, António Amaral, Teresa Barros,
This paper aims to identify and analyze project management maturity models in order to identify those best suited to be adopted in construction firms. To do so, models from papers available in academic repositories were analyzed. To be successful, the construction business deeply depends on projects outcomes; thus, the implementation of project management maturity models is important for this sector. A maturity model is a valuable technique to assess project management capabilities within a single ...
Tópico(s): Value Engineering and Management
2021 - Multidisciplinary Digital Publishing Institute | Journal of risk and financial management
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Ivana Beatrice Mânica da Cruz, Antônio Lourenço Severo, Verônica Farina Azzolin, Luiz Filipe Machado Garcia, André Kühn, Osvandré Lech,
Os avanços nos estudos com células‐tronco mesenquimais (CTMs) adultas tornou a terapia regenerativa tecidual uma ferramenta promissora em diversas áreas da medicina. Na ortopedia, um dos principais desafios tem sido a regeneração do tecido cartilaginoso, sobretudo em diartroses. Na indução de CTMs, além da citodiferenciação, o contexto microambiental do tecido a ser regenerado, bem como uma disposição espacial adequada, são fatores de extrema importância. Além disso, sabe‐se que a diferenciação das ...
Tópico(s): Mesenchymal stem cell research
2016 - Thieme Medical Publishers (Germany) | Revista Brasileira de Ortopedia
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII
Joaquim Carneiro, Filipe Machado, M. Pereira, V. Teixeira, Manuel F. M. Costa, Artur Ribeiro, Artur Cavaco‐Paulo, A.P. Samantilleke,
This work is devoted to the study of the influence of different anodic aluminium oxide (AAO) morphologies on the sensitivity and performance of an AAO-based capacitive touch sensor. The AAO structures were fabricated in a cylindrical homemade anodization cell made from a solid polycarbonate billet via a lathe machining process. The AAO morphologies were obtained from the anodization of Al foil by using three different types of electrolyte (sulphuric acid, oxalic acid and phosphoric acid) and their ...
Tópico(s): Conducting polymers and applications
2018 - Royal Society of Chemistry | RSC Advances
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Róberson Machado Pimentel, Geraldo Fábio Viana Bayão, Daiana Lopes Lelis, Alex Júnio da Silva Cardoso, Filipe Vélez Saldarriaga, Carlos Cicinato Vieira Melo, Filipe Bittencourt Machado de Souza, Ana Claúdia de Souza Pimentel, Dilermando Miranda da Fonseca, Manoel Eduardo Rozalino Santos,
The study was conducted in order to conduct a review of the importance of ecophysiology of forage plants, to address the impacts of biotic and abiotic factors on plants and their morphological and physiological responses. The physical stress caused by soil compaction affect the development of the root system, is this condition plant shown as response greater emission lateral roots as an alternative to explore larger volume of soil. The flooding condition affect forage species differently. In this ...
Tópico(s): Agroforestry and silvopastoral systems
2016 - Editora MV Valero | PubVet
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Rômulo Pillon Barcelos, Rafael de Lima Portella, Thiago Henrique Lugokenski, Edovando José Flores da Rosa, Guilherme Pires Amaral, Luiz Filipe Machado Garcia, Leandro Bresolin, Vanessa Santana Carratu, Félix Alexandre Antunes Soares, Nilda Vargas Barbosa,
Organophosphates (OPs), which are widely used as pesticides, are acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors. The inactivation of AChE results in the accumulation of acetylcholine at cholinergic receptor sites, causing a cholinergic crisis that can lead to death. The classical treatment for OP poisoning is administration of oximes, but these compounds are ineffective in some cases. Here we determined whether the new compound isatin-3-N(4)-benzilthiosemicarbazone (IBTC), which ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2012 - Elsevier BV | Toxicology in Vitro
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Graziela de Sá Machado Araújo, Ronaldo da Silva Francisco, Cristina dos Santos Ferreira, Pedro Thyago Mozer Rodrigues, Douglas Terra Machado, Thaís Louvain de Souza, Jozimara Teixeira de Souza, Cleiton Figueiredo Osório da Silva, Antônio Francisco Alves da Silva, Cláudia Caixeta Franco Andrade, Alan Tardin da Silva, Víctor Ramos, Ana Beatriz Garcia, Filipe Brum Machado, Enrique Medina‐Acosta,
A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5mC) of alleles at CpG islands (CGIs) in their promoter regions. This 5mCpG asymmetry between the parental alleles creates allele-specific imprinted differentially methylated regions (iDMRs). iDMRs are often coupled to the transcriptional repression of the methylated allele and the activation of the unmethylated allele in a tissue-specific, developmental-stage-specific and/ ...
Tópico(s): Prenatal Screening and Diagnostics
2018 - Frontiers Media | Frontiers in Genetics
... 29 May, 1645. f. 39 ;-(b) Report by Filipe de Matos [Cotrim], Sarcento Mor of Moura [in ... 31.] 64. Report to the King by Francisco Machado, Provedor Mor da Fazenda do Estado do Maranhão, ...
1729 - Gale Group | SASII

Paula Nogueira Curi, Cynara dos Santos CARVALHO, Derlyene Lucas SALGADO, Rafael Pio, Moacir Pasqual, Filipe Bittencourt Machado de Souza, Vanessa Rios de Souza,
The objective of this study was to evaluate the influence of different types of sugar (white refined sugar, white crystal sugar, demerara sugar, brown sugar and coconut sugar) on the physicochemical characteristics, rheological properties and sensory acceptance of physalis (Physalis L) jelly. In addition, we evaluated the influence of the information on the acceptability of the product. It was found that the type of sugar greatly influences the physicochemical and rheological characteristics of physalis ...
Tópico(s): Postharvest Quality and Shelf Life Management
2017 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology