
Maurício Malavasi Ganança, Heloísa Helena Caovilla, Mário Sérgio Lei Munhoz, Cristina Freitas Ganança, Maria Leonor Garcia da Silva, Flávio Serafini, Fernando Freitas Ganança,
Drug treatment is an important option for the treatment of peripheral vestibular diseases.To identify the drug component associated with optimal integrated balance therapy (IBT) for Ménières disease or other peripheral vestibular disorders.Analysis of a series of patients with Ménières disease patients or patients with other peripheral vestibular disorders that received IBT involving either no medication or betahistine, cinnarizine, clonazepam, flunarizine or Ginkgo biloba during 120 days.In Ménières ...
Tópico(s): Ocular Surface and Contact Lens
2007 - Elsevier BV | Brazilian Journal of Otorhinolaryngology

Maurício Malavasi Ganança, Heloísa Helena Caovilla, Mário Sérgio Lei Munhoz, Cristina Freitas Ganança, Maria Leonor Garcia da Silva, Flávio Serafini, Fernando Freitas Ganança,
A farmacoterapia é opção importante no tratamento das vestibulopatias periféricas. OBJETIVO: Identificar a medicação que otimiza a terapia integrada da vertigem (TIV) na doença de Ménière e em outras vestibulopatias periféricas. MATERIAL E MÉTODO: Estudo de casos em que pacientes com doença de Ménière ou outras vestibulopatias periféricas receberam TIV com betaistina, cinarizina, clonazepam, flunarizina, Ginkgo biloba ou sem medicação durante 120 dias. RESULTADOS: Na doença de Ménière, TIV com qualquer ...
Tópico(s): Ocular Surface and Contact Lens
2007 - Sociedade Brasileira de Otorrinolaringologia | Revista Brasileira de Otorrinolaringologia
Gianmarco Rosa, Chiara Giannotti, Lucia Martella, Federico Massa, Gianluca Serafini, Matteo Pardini, Flavio Nobili, Fiammetta Monacelli,
Dementia is an age-related clinical condition, with higher incidence rates in older ages. However, there is some evidence that a reverse epidemiology is also observed. Namely, the cohort analysis of dementia incidence rates by birth in selected populations demonstrated a decreased incidence of dementia in late life across the last twenty years, possibly due to decreased incidence of cardiovascular disorders and increased education and cognitive reserve. In line with that, age is probably a proxy ...
Tópico(s): Alzheimer's disease research and treatments
2020 - IOS Press | Journal of Alzheimer s Disease

Lucindo José Quintans‐Júnior, Adriano Antunes de Souza Araújo, Renan Guedes de Brito, Priscila L. Santos, Jullyana de Souza Siqueira Quintans, Paula dos Passos Menezes, Mairim Russo Serafini, Gabriel Francisco da Silva, Flavio M. S. Carvalho, Nicole K. Brogden, Kathleen A. Sluka,
Evaluate the anti-hyperalgesic effect of the complex containing β-caryophyllene (βCP) and β-cyclodextrin (βCD) in a non-inflammatory chronic muscle pain mice model and investigated its action on superficial dorsal horn of the lumbar spinal cord. The βCP-βCD complex were prepared and characterized through the DSC, TG/DTG, FTIR, XRD and SEM. The model of chronic muscle pain was induced by two injections of pH 4.0 saline (20 μL) into left gastrocnemius 5 days apart. After confirming hyperalgesia, male ...
Tópico(s): Myofascial pain diagnosis and treatment
2016 - Elsevier BV | Life Sciences

Filipe Filletti, Hiran Rocha Guillaumon, Flávio Serafini, Nelson de Almeida Filho,
Introduction: Noise-induced hearing loss is a sensorineural hearing loss, usually bilateral, irreversible and progressive with time of exposure. As the noise made by children in school may be considered detrimental, the study looks of their occurrence in Taubaté's schools. Objective: To determine if students are exposed to noise intensity affecting the cochlea, define the profile of these schoolchildren, demonstrating the occurrence of changes in cochlear activity following exposure to noise in a day of class. ...
Tópico(s): Injury Epidemiology and Prevention
2012 - Georg Thieme Verlag | Arquivos Internacionais de Otorrinolaringologia
Andrea Necchi, Nicola Nicolai, Alessandra Alessi, Rosalba Miceli, Patrizia Giannatempo, Daniele Raggi, S. Tana, Gianluca Serafini, Barbara Padovano, Luigi Mariani, Flavio Crippa, Roberto Salvioni,
Abstract Background In patients with metastatic seminoma, designing a risk-adapted strategy that may help personalize the burden of treatment and follow-up is required. Patients and Methods Patients who were administered cisplatin, etoposide, and bleomycin (PEB) were staged at baseline with computed tomography (CT), positron emission tomography (PET), and serum tumor markers. Restaging was then performed with PET after 2 cycles of PEB (PET 2 ) and with CT after 3 to 4 cycles of treatment. The 20% cutoff of maximal ...
Tópico(s): Sarcoma Diagnosis and Treatment
2015 - Elsevier BV | Clinical Genitourinary Cancer
Flavio Pressacco, Paolo Serafini,
In a recent critical review of de Finetti's paper "Il problema dei pieni'', the Nobel Prize winner Harry Markowitz recognized the primacy of de Finetti in applying the mean-variance approach to finance, but pointed out that de Finetti did not solve the problem for the general case of correlated risks. We argue in this paper that a more fair sentence would be: de Finetti did solve the general problem but under an implicit hypothesis of regularity which is not always satisfied. Moreover, a natural ...
Tópico(s): Economic theories and models
2007 - Springer Science+Business Media | Decisions in Economics and Finance
Beatrice Orso, Chiara Mattei, Dario Arnaldi, Federico Massa, Gianluca Serafini, Domenico Plantone, Elisa Doglione, Jordan Grafman, Flavio Nobili, Matteo Pardini,
Objective As an analogy with mild cognitive impairment (MCI), the mild behavioral impairment (MBI) construct has been proposed as a diagnostic label for those presenting late-onset behavioral symptoms. To date, however, the clinical, cognitive, and structural imaging features associated with an increased risk of conversion from MBI to dementia are poorly understood. Methods We retrospectively analyzed the cognitive performance and structural brain MRI of 113 subjects, with a clinical follow-up of ...
Tópico(s): Epilepsy research and treatment
2019 - Elsevier BV | American Journal of Geriatric Psychiatry
Flavio Pressacco, Paolo Serafini, Laura Ziani,
The paper concerns optimal mean–variance proportional reinsurance under group correlation. In order to solve the corresponding constrained quadratic optimization problem, we make large recourse both to the smart friendly technique originally proposed by B. de Finetti in his pioneering paper (Giornale Istituto Italiano Attuari 9:1–88, 1940) and to the well known Karush–Kuhn–Tucker conditions for constrained optimization. We offer closed form results and insightful considerations about the problem. ...
Tópico(s): Statistical Methods and Inference
2011 - Springer Nature | European Actuarial Journal
Roberto Mosca, Vinicius Mayo, Camila Lamarão,
... FEMECS). A presente entrevista é um depoimento de Flavio Serafini, professor de Sociologia da Escola Politécnica de Saúde ...
Tópico(s): Youth, Politics, and Society
2021 - | Perspectiva Sociológica A Revista de Professores de Sociologia
W.C. Hülsmann, Alessandro Peschechera, Flávio Serafini, Liliana Ferrari,
Tópico(s): Cardiac Ischemia and Reperfusion
1996 - Springer Science+Business Media | Molecular and Cellular Biochemistry

Felipe Ornell, Juliana Nichterwitz Scherer, Jaqueline Bohrer Schuch, Anne Orgler Sordi, Silvia Chwartzmann Halpern, Fernando Pezzini Rebelatto, Giovana Bristot, Flávio Kapczinski, Vinícius Serafini Roglio, Flávio Pechansky, Félix Henrique Paim Kessler, Lísia von Diemen,
Tópico(s): Obsessive-Compulsive Spectrum Disorders
2023 - Elsevier BV | Alcohol
Aristides Gionis, Flavio Junqueira, Vincent Leroy, Marco Serafini, Ingmar Weber,
The popularity of social-networking sites has increased rapidly over the last decade. A basic functionalities of social-networking sites is to present users with streams of events shared by their friends. At a systems level, materialized per-user views are a common way to assemble and deliver such event streams on-line and with low latency. Access to the data stores, which keep the user views, is a major bottleneck of social-networking systems. We propose to improve the throughput of these systems ...
Tópico(s): Cloud Computing and Resource Management
2013 - Association for Computing Machinery | Proceedings of the VLDB Endowment

Silvia Chwartzmann Halpern, Juliana Nichterwitz Scherer, Vinícius Serafini Roglio, Sibele Faller, Anne Orgler Sordi, Felipe Ornell, Carla Dalbosco, Flávio Pechansky, Félix Henrique Paim Kessler, Lísia von Diemen,
Resumo: O estudo teve como objetivo avaliar a gravidade do uso de substâncias psicoativas, situações de violência, saúde física e emocional de usuários de crack que buscam atendimento em Centros de Atenção Psicossocial para Álcool e Drogas (CAPSad), em relação ao status de moradia. Trata-se de um estudo multicêntrico em seis capitais brasileiras, com 564 usuários de crack categorizados em dois grupos: (1) usuários que estiveram em situação de rua (n = 266) e (2) nunca estiveram em situação de rua (n = 298). ...
Tópico(s): Homelessness and Social Issues
2017 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública

Karina Proença Ligabue, Jaqueline Bohrer Schuch, Juliana Nichterwitz Scherer, Felipe Ornell, Vinícius Serafini Roglio, Vanessa Aparecida Flores de Assunção, Fernando Pezzini Rebelatto, Maria Paz Hildalgo, Flávio Pechansky, Félix Henrique Paim Kessler, Lísia von Diemen,
Dysregulation of the hypothalamic–pituitaryadrenal (HPA) axis has been associated with craving and early relapse among individuals with substance use disorders. However, no association has been postulated regarding treatment retention and prognosis in crack cocaine users. Our aim was to investigate the association between morning salivary cortisol levels and treatment retention in crack cocaine users. 44 male crack cocaine users were recruited from a detoxification unit. Saliva collection was performed ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2019 - Elsevier BV | Addictive Behaviors
Alessandra Alessi, Alice Lorenzoni, Anna Cavallo, Barbara Padovano, Nicola Alessandro Iacovelli, Paolo Bossi, Salvatore Alfieri, Gianluca Serafini, Carlotta Benedetta Colombo, A. Cicchetti, Marta Mira-Aladrén, Lisa Licitra, C. Fallai, Flavio Crippa, Ester Orlandi,
To evaluate the prognostic role of pretreatment 18F-FDG PET/CT metabolic parameters in non-endemic Epstein–Barr Virus (EBV DNA)-related nasopharyngeal cancer (NPC) patients treated with curative intensity-modulated radiation therapy (IMRT) with or without chemotherapy (CHT). We retrospectively reviewed clinical data of 160 consecutive non-metastatic NPC patients who received IMRT with or without CHT. Forty-nine out of 160 patients that underwent whole body 18F-FDG PET/CT at our institution for disease ...
Tópico(s): Lymphoma Diagnosis and Treatment
2018 - Springer Science+Business Media | La radiologia medica

Juliana Nichterwitz Scherer, Roberta Bristot Silvestrin, Felipe Ornell, Vinícius Serafini Roglio, Tanara Vieira Sousa, Lísia von Diemen, Félix Henrique Paim Kessler, Flávio Pechansky,
Substance use disorders are associated with the increased risk of driving under the influence (DUI), but little is known about crack-cocaine and its relationship with road traffic crashes (RTC).A multicenter sample of 765 crack-cocaine users was recruited in six Brazilian capitals in order to estimate the prevalence of DUI and RTC involvement. Legal, psychiatric, and drug-use aspects related with traffic safety were evaluated using the Addiction Severity Index - 6th version (ASI-6) and the Mini International ...
Tópico(s): Cannabis and Cannabinoid Research
2016 - Elsevier BV | Drug and Alcohol Dependence
Gianluca Serafini, Matteo Pardini, Fiammetta Monacelli, Beatrice Orso, Nicola Girtler, Andrea Brugnolo, Mario Amore, Flavio Nobili,
Bipolar disorder (BD) is a chronic and disabling psychiatric condition that is linked to significant disability and psychosocial impairment. Although current neuropsychological, molecular, and neuroimaging evidence support the existence of neuroprogression and its effects on the course and outcome of this condition, whether and to what extent neuroprogressive changes may impact the illness trajectory is still poorly understood. Thus, this selective review was aimed toward comprehensively and critically ...
Tópico(s): Electrolyte and hormonal disorders
2021 - Multidisciplinary Digital Publishing Institute | Brain Sciences

Paula Pimentel Valente, Gustavo Henrique Ferreira Abreu Moreira, Matheus Ferreira Serafini, Elias Jorge Facury-Filho, A.Ú. Carvalho, André Augusto Gomes Faraco, Rachel Oliveira Castilho, Múcio Flávio Barbosa Ribeiro,
Tópico(s): Vector-borne infectious diseases
2017 - Springer Science+Business Media | Parasitology Research
Paula dos Passos Menezes, Mairim Russo Serafini, Lucindo José Quintans‐Júnior, Gustavo Francisco Santos da Silva, Juliana Ferreira de Oliveira, Flávio Machado de Souza Carvalho, J. C. C. de Souza, Jivaldo do Rosário Matos, Péricles Barreto Alves, Iara Lisboa de Matos, Daniel I. Hădărugă, Adriano Antunes de Souza Araújo,
Tópico(s): Crystallization and Solubility Studies
2014 - Springer Science+Business Media | Journal of Thermal Analysis and Calorimetry

Mayara Schulze Cosechen, Adma Silva de Lima Wojcik, Flávio Meingast Piva, Betina Werner, Sérgio Zuñeda Serafini,
A adenomatose erosiva do mamilo é uma complexa proliferação benigna mamária que pode ser confundida com neoplasias malignas da mama. A apresentação típica cursa com descarga mamária, eritema, erosão e formação de crostas. O processo é geralmente assintomático e de instalação insidiosa. A adenomatose erosiva do mamilo pode ser confundida com condições benignas, como a dermatite de contato, psoríase e infecções, mas seu principal diagnóstico diferencial é a Doença de Paget. O tratamento é cirúrgico ...
Tópico(s): Cancer Diagnosis and Treatment
2011 - Elsevier BV | Anais Brasileiros de Dermatologia
Alessandra Alessi, Fabio Martinelli, Barbara Padovano, Gianluca Serafini, Domenica Lorusso, Alice Lorenzoni, Antonino Ditto, Francesca Lecce, Marta Mira-Aladrén, Cristina Donfrancesco, Francesco Raspagliesi, Flavio Crippa,
Aims and background Primary cytoreductive surgery (CRS) has a significant impact on prognosis in epithelial ovarian cancer (EOC). Patient selection is important to recognize factors limiting optimal CRS and to avoid unnecessary aggressive surgical procedures. We evaluated the contribution of fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in the presurgical identification of disease sites that may preclude EOC cytoreducibility. Methods Patients with suspected EOC ...
Tópico(s): Endometriosis Research and Treatment
2015 - SAGE Publishing | Tumori Journal
Flavio Junqueira, Marco Serafini,
Active replication is commonly built on top of the atomic broadcast primitive. Passive replication, which has been recently used in the popular ZooKeeper coordination system, can be naturally built on top of the primary-order atomic broadcast primitive. Passive replication differs from active replication in that it requires processes to cross a barrier before they become primaries and start broadcasting messages. In this paper, we propose a barrier function τ that explains and encapsulates the differences ...
Tópico(s): Optimization and Search Problems
2013 - Springer Science+Business Media | Lecture notes in computer science

Milton Armando Teresa Malai Moçambique, Aline Hoffmann, Vinícius Serafini Roglio, Félix Henrique Paim Kessler, Carla Dalbosco, Jaqueline Bohrer Schuch, Flávio Pechansky,
0 0 -0 0 0 0 -0 0 0 0 -0 0 0 0 Aline Hoffmann, 1 Vinı ´cius S. Roglio, 1,2 0 0 0 0 -0 0 0 0 -0 0 0 0 -0 0 0 0 Felix H.P. Kessler, 1,2 0 0 0 0 -0 0 0 0 -0 0 0 0 -0 0 0 0 Carla Dalbosco, 1 0 0 0 0 -0 0 0 0 -0 0 0 0 -0 0 0 0 Jaqueline B. Schuch,
Tópico(s): Poisoning and overdose treatments
2022 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry

Andrei Garziera Valério, Juliana Nichterwitz Scherer, Flávio Pechansky, Lísia von Diemen, Felipe Ornell, Vinícius Serafini Roglio, Jaqueline Bohrer Schuch, Giovana Bristot, Flávio Kapczinski, Félix Henrique Paim Kessler,
Changes in brain-derived neurotrophic factor (BDNF) have been linked to the neuroadaptative consequences of chronic alcohol use and associated with disease severity and prognosis. Few studies have evaluated the influence of drug withdrawal and clinical and sociodemographic data on BDNF levels in severe alcohol users.Our goals were (1) to evaluate variation in BDNF levels during alcohol withdrawal and, (2) to assess the influence of putative confounding factors on BDNF levels.Our sample consists of ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2021 - Associação de Psiquiatria do Rio Grande do Sul | Trends in Psychiatry and Psychotherapy
Roberto Mosca, Vinicius Mayo, Camila Lamarão,
... Janeiro (UFRJ). Na sequência, temos a entrevista de Flavio Serafini, professor de Sociologia da Escola Politécnica de Saúde ...
Tópico(s): Sociology and Education in Brazil
2021 - | Perspectiva Sociológica A Revista de Professores de Sociologia
Diogo Becker, Flavio Junqueira, Marco Serafini,
Replicated services often rely on a leader to order client requests and broadcast state updates. In this work, we present POLE, a leader election algorithm that select leaders using application-specific scores. This flexibility given to the application enables the algorithm to tailor leader election according to metrics that are relevant in practical settings and that have been overlooked by existing approaches. Recovery time and request latency are examples of such metrics. To evaluate POLE, we ...
Tópico(s): Service-Oriented Architecture and Web Services
2011 - Springer Science+Business Media | Lecture notes in computer science
Arianna Latini, Cipriano Foxi, Flavio Borfecchia, Andrea Lentini, Luigi De Cecco, Domenico Iantosca, Mauro Serafini, U. Laneri, Marco Citterio, Alessandro Campiotti, Giovanni Benelli, Susanna Mariani,
Tópico(s): Insect-Plant Interactions and Control
2019 - Springer Science+Business Media | Environmental Science and Pollution Research
Patrizia Giannatempo, Alessandra Alessi, Rosalba Miceli, Daniele Raggi, Elena Farè, Nicola Nicolai, Gianluca Serafini, Barbara Padovano, Luigi Piva, Davide Biasoni, Tullio Torelli, Mario Catanzaro, Silvia Stagni, Massimo Maffezzini, Luigi Mariani, Alessandro M. Gianni, Guru Sonpavde, Roberto Salvioni, Andrea Necchi, Flavio Crippa,
Background The prognostic impact of early metabolic response by fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) after 2 cycles of first-line chemotherapy is still unrecognized in metastatic transitional cell carcinoma (TCC). Patients and Methods Patients with metastatic TCC receiving the modified combination of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC), according to institutional protocol, underwent computed tomography (CT) and FDG-PET imaging at baseline, a ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2014 - Elsevier BV | Clinical Genitourinary Cancer

Vinícius Serafini Roglio, Eduardo Nunes Borges, Francisco Diego Rabelo-da-Ponte, Felipe Ornell, Juliana Nichterwitz Scherer, Jaqueline Bohrer Schuch, Ives Cavalcante Passos, Breno Sanvicente‐Vieira, Rodrigo Grassi‐Oliveira, Lísia von Diemen, Flávio Pechansky, Félix Henrique Paim Kessler,
Background Suicide is a severe health problem, with high rates in individuals with addiction. Considering the lack of studies exploring suicide predictors in this population, we aimed to investigate factors associated with attempted suicide in inpatients diagnosed with cocaine use disorder using two analytical approaches. Methods This is a cross-sectional study using a secondary database with 247 men and 442 women hospitalized for cocaine use disorder. Clinical assessment included the Addiction ...
Tópico(s): Forensic Toxicology and Drug Analysis
2020 - Public Library of Science | PLoS ONE