Isabelle Fernandes, Hélène Chanut-Delalande, Pierre Ferrer, Yvan Latapie, Lucas Waltzer, Markus Affolter, François Payre, Serge Plaza,
Summary The zona pellucida domain (ZPD) defines a conserved family of membrane-anchored matrix proteins that are, as yet, poorly characterized with respect to their functions during development. Using genetic approaches in flies, we show here that a set of eight ZPD proteins is required for the localized reorganization of embryonic epidermal cells during morphogenesis. Despite varying degrees of sequence conservation, these ZPD proteins exert specific and nonredundant functions in the remodeling of epidermal ...
Tópico(s): Ubiquitin and proteasome pathways
2010 - Elsevier BV | Developmental Cell
Hélène Chanut-Delalande, Alain C. Jung, Magdalena M. Baer, Lin Li, François Payre, Markus Affolter,
Background Endocytosis is a key regulatory step of diverse signalling pathways, including receptor tyrosine kinase (RTK) signalling. Hrs and Stam constitute the ESCRT-0 complex that controls the initial selection of ubiquitinated proteins, which will subsequently be degraded in lysosomes. It has been well established ex vivo and during Drosophila embryogenesis that Hrs promotes EGFR down regulation. We have recently isolated the first mutations of stam in flies and shown that Stam is required for ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2010 - Public Library of Science | PLoS ONE
Céline J. Fischer Fumeaux, Clara L. García‐Ródenas, Carlos Antonio De Castro, Marie‐Claude Courtet‐Compondu, Sagar K. Thakkar, Lydie Beauport, Jean‐François Tolsa, Michael Affolter,
Background: Mother’s own milk is the optimal source of nutrients and provides numerous health advantages for mothers and infants. As they have supplementary nutritional needs, very preterm infants may require fortification of human milk (HM). Addressing HM composition and variations is essential to optimize HM fortification strategies for these vulnerable infants. Aims: To analyze and compare macronutrient composition in HM of mothers lactating very preterm (PT) (28 0/7 to 32 6/7 weeks of gestational ...
Tópico(s): Child Nutrition and Water Access
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Karine Redeuil, Antoine Lévèques, Jean‐Marie Oberson, Sylvie Bénet, Emeline Tissot, Karin Longet, Antonio de Castro, Céline Romagny, Lydie Beauport, Céline J. Fischer Fumeaux, Jean‐François Tolsa, Michael Affolter, Esther Campos Giménez, Clara L. García‐Ródenas, Sagar K. Thakkar,
Differences in vitamin and carotenoids content of human milk (HM) produced for infants born at term and preterm is poorly understood. In this study, HM was collected weekly for four and two months post-partum for preterm and term groups, respectively. Nutrients of interest, from single full breast expressions were measured by liquid chromatography coupled with mass spectrometry. Microbiological assay was employed for vitamin B12. When compared at equivalent post-partum age, vitamins B1, B2, B6, and ...
Tópico(s): Birth, Development, and Health
2020 - Elsevier BV | Clinical Nutrition
Sean Austin, Carlos Antonio De Castro, Norbert Sprenger, Aristea Binia, Michael Affolter, Clara L. García‐Ródenas, Lydie Beauport, Jean‐François Tolsa, Céline J. Fischer Fumeaux,
Human milk oligosaccharides (HMOs) are a major component of human milk, and play an important role in protecting the infant from infections. Preterm infants are particularly vulnerable, but have improved outcomes if fed with human milk. This study aimed to determine if the HMO composition of preterm milk differed from that of term milk at equivalent stage of lactation and equivalent postmenstrual age. In all, 22 HMOs were analyzed in 500 samples of milk from 25 mothers breastfeeding very preterm ...
Tópico(s): Child Nutrition and Water Access
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Clara L. García‐Ródenas, Carlos Antonio De Castro, Rosemarie Jenni, Sagar K. Thakkar, Lydie Beauport, Jean‐François Tolsa, Céline Fischer-Fumeaux, Michael Affolter,
Background Proteins are major contributors to the beneficial effects of human milk (HM) on preterm infant health and development. Alpha-lactalbumin, lactoferrin, serum albumin and caseins represent approximately 85% of the total HM protein. The temporal changes of these proteins in preterm (PT) HM and its comparison with term (T) HM is poorly characterized. Aims To quantify and compare the temporal changes of the major proteins in PT HM and T HM. Methods HM was collected for 4 months postpartum at ...
Tópico(s): Neonatal Respiratory Health Research
2018 - Elsevier BV | Clinical Nutrition
Sagar K. Thakkar, Carlos Antonio De Castro, Lydie Beauport, Jean‐François Tolsa, Céline J. Fischer Fumeaux, Michael Affolter, Francesca Giuffrida,
We longitudinally compared fatty acids (FA) from human milk (HM) of mothers delivering term and preterm infants. HM was collected for 4 months postpartum at 12 time points for preterm and for 2 months postpartum at 8 time points for term group. Samples were collected from the first feed of the morning, and single breast was fully expressed. FA were analyzed by gas chromatography coupled with flame ionization detector. Oleic, palmitic and linoleic acids were the most abundant FA across lactation and ...
Tópico(s): Neonatal Respiratory Health Research
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Magalie Sabatier, Clara L. García‐Ródenas, Carlos Antonio De Castro, Peter Kastenmayer, Mario Vigo, Stéphane Dubascoux, Daniel Andrey, Marine Nicolas, Janique Richoz Payot, Valentine Bordier, Sagar K. Thakkar, Lydie Beauport, Jean‐François Tolsa, Céline J. Fischer Fumeaux, Michael Affolter,
An adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28-32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group (
Tópico(s): Breastfeeding Practices and Influences
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Félix N. Büchi, Jean-François Affolter, Stefan Camenzind, Niels Chmielewski, Philipp Dietrich, Michael Höckel, Martin Ruge, Marco Santis,
This article gives an overview on the research and development activities pursued in the area of polymer electrolyte fuel cell stacks and systems in Switzerland in 2004. Work is pursued on several different levels for stacks and systems from portable to automotive applications, in the academic as well as in the industrial area. Today's work focuses on the improvement of specific power and cost efficiency of stacks and systems by development and optimization of new concepts for water management and ...
Tópico(s): Electrocatalysts for Energy Conversion
2004 - Swiss Chemical Society | CHIMIA International Journal for Chemistry
Paul Fernandes, Jean‐Paul Raynal, Pascal Tallet, Christophe Tufféry, Michel Piboule, Micheline Séronie-Vivien, Marie‐Roger Séronie‐Vivien, Alain Turq, André Morala, Jehanne Affolter, Dominique Millet, Françoise Millet, Frédéric Bazile, Patrick Schmidt, Pascal Foucher, Vincent Delvigne, Jérémie Liagre, Stéphane Gaillot, Alexandre Morin, Marie‐Hélène Moncel, Jean-François Garnier, Céline Léandri-Bressy,
Une carte des principales formations à silex du sud de la France est en cours de réalisation. Elle propose, à tous les préhistoriens, une base nécessaire au développement d'études interrégionales sur la circulation des silex. Elle est le fruit d'une collaboration entre des acteurs impliqués dans la problématique de caractérisation de la provenance des silex. Elle regroupe les résultats de leurs prospections systématiques ou ciblées dans six régions (Aquitaine, Auvergne, Languedoc-Roussillon, Midi- ...
Tópico(s): Geochemistry and Geologic Mapping
2013 - | Paléo
Emilie Zuercher, Christophe Butticaz, Josiane Wyniger, Raquel Martínez, Manuel Battegay, Emmanuelle Boffi El Amari, Thanh Dang, Jean‐François Egger, Jan Fehr, Esther Mueller-Garamvögyi, Andrea Parini, Stephan Schaefer, Franziska Schoeni‐Affolter, Christine Thurnheer, Marianne Tinguely, Amalio Telenti, Sylvia Rothenberger,
Epstein-Barr virus (EBV) is associated with several types of cancers including Hodgkin's lymphoma (HL) and nasopharyngeal carcinoma (NPC). EBV-encoded latent membrane protein 1 (LMP1), a multifunctional oncoprotein, is a powerful activator of the transcription factor NF-κB, a property that is essential for EBV-transformed lymphoblastoid cell survival. Previous studies reported LMP1 sequence variations and induction of higher NF-κB activation levels compared to the prototype B95-8 LMP1 by some variants. ...
Tópico(s): Lymphoma Diagnosis and Treatment
2012 - Public Library of Science | PLoS ONE
François‐Pierre Martin, Britta Spanier, Sebastiano Collino, Ivan Montoliu, Carolin A. Kolmeder, Pieter Giesbertz, Michael Affolter, Martin Kussmann, Hannelore Daniel, Sunil Kochhar, Serge Rezzi,
Insulin/IGF-like signaling (IIS) and nutrient sensing are among the most potent regulators of health status and aging. Here, a global view of the metabolic changes in C. elegans with impaired function of IIS represented by daf-2 and daf-16 and the intestinal di- and tripeptide transport pept-1 was generated using (1)H nuclear magnetic resonance spectroscopic analysis of worm extracts and spent culture media. We showed that specific metabolic profiles were significantly associated with each type of ...
Tópico(s): Gut microbiota and health
2011 - American Chemical Society | Journal of Proteome Research
Produção Nacional
Revisado por pares
Pierre‐Alain Binz, Fadi Abdi, Michael Affolter, Laure Allard, Jachen Barblan, Sanjeev K. Bhardwaj, Willy V. Bienvenut, Philippe Bulet, Jennifer Burgess, Odile Carrette, Garry L. Corthals, François Delalande, Hélène Diemer, Philippe Favreau, Giuliano Elia, Yannick Gueguen, Elisabeth Guillaume, Stefanie Hahner, Petr Man, Sophie Michalet, Dario Neri, Dimitrios Noukakis, Patricia M. Palagi, Pierre Paroutaud, Daniel C. Pimenta, Manfredo Quadroni, Anja Resemann, Sophie Richert, Jascha Rybak, Jean‐Charles Sanchez, Alexander Scherl, Simone Scheurer, Ulrike Schweiger Hufnagel, Christoph Siethoff, Detlev Suckau, Alain Van Dorsselaer, Winfried Wagner Redeker, Nadia Walter, Reto Stöcklin,
Abstract After the success of the mass spectrometry (MS) round table that was held at the first Swiss Proteomics Society congress (SPS'01) in Geneva, the SPS has organized a proteomics application exercise and allocated a full session at the SPS'02 congress. The main objective was to encourage the exchange of expertise in protein identification, with a focus on the use of mass spectrometry, and to create a bridge between the users’ questions and the instrument providers’ solutions. Two samples were ...
Tópico(s): Antimicrobial Peptides and Activities
2003 - Wiley | PROTEOMICS
Martin Blüggel, François Spertini, Petra Lutter, Jacqueline Wassenberg, R Audran, Blaise Corthésy, Stefan Müllner, Stéphanie Blum, Andreas Wattenberg, Annick Mercenier, Michael Affolter, Martin Kussmann,
Allergy is an immunological disorder of the upper airways, lung, skin, and the gut with a growing prevalence over the last decades in Western countries. Atopy, the genetic predisposition for allergy, is strongly dependent on familial inheritance and environmental factors. These observations call for predictive markers of progression from atopy to allergy, a prerequisite to any active intervention in neonates and children (prophylactic interventions/primary prevention) or in adults (immunomodulatory ...
Tópico(s): Allergic Rhinitis and Sensitization
2011 - American Chemical Society | Journal of Proteome Research
Kavita Arora, Michael B. O’Connor, Rahul Warrior,
... Cell 78: 251– 261. 47 Nellen, D., M. Affolter, & K. Basler 1994. Receptor Serine/Threonine kinases implicated ... mesoderm of Drosophila. Development 117: 1211– 1222. 57 Affolter, M., D. Nellen, U. Nussbaumer & K. Basler 1994. ... C., D. Nellen, R. Burke, K. Basler & M. Affolter 1995. schnurri is required for Drosophila Dpp signaling ...
Tópico(s): TGF-β signaling in diseases
1996 - Wiley | Annals of the New York Academy of Sciences
Miguel Manzanares, Jeannette Nardelli, Pascale Gilardi‐Hebenstreit, Heather Marshall, François Giudicelli, María Teresa Martínez‐Pastor, Robb Krumlauf, Patrick Charnay,
... interactions in association with other factors (Mann and Affolter, 1998; Affolter and Mann, 2001). In this regard, segmental expression ...
Tópico(s): Hedgehog Signaling Pathway Studies
2002 - Springer Nature | The EMBO Journal
Melissa M. Lakich, Thierry T. Diagana, Daniel North, Robert G. Whalen,
... Tokunaga K. Schier A.F. Resendez-Perez D. Affolter M. Otting G. Würthrich K. Cell. 1994; 78: ... Tokunaga K. Schier A.F. Resendez-Perez D. Affolter M. Otting G. Würthrich K. Cell. 1994; 78: ... for the MEF-2C expression vector; and Prof. François Gros for continuous support.
Tópico(s): RNA modifications and cancer
1998 - Elsevier BV | Journal of Biological Chemistry
Chris Wymant, Daniela Bezemer, François Blanquart, Luca Ferretti, Astrid Gall, Matthew Hall, Tanya Golubchik, Margreet Bakker, Swee Hoe Ong, Lele Zhao, David Bonsall, Mariateresa de Cesare, George MacIntyre-Cockett, Lucie Abeler‐Dörner, Jan Albert, Norbert Bannert, Jacques Fellay, M. Kate Grabowski, Barbara Bartmeyer, Huldrych F. Günthard, Pia Kivelä, Roger D. Kouyos, Oliver Laeyendecker, Laurence Meyer, Kholoud Porter, Matti Ristola, Ard van Sighem, Ben Berkhout, Paul Kellam, Marion Cornelissen, Peter Reiss, Christophe Fraser, Vincent Aubert, Manuel Battegay, Enos Bernasconi, Jürg Böni, Dominique L. Braun, H C Bucher, Claudine Burton‐Jeangros, Alexandra Calmy, Matthias Cavassini, G Dollenmaier, Matthias Egger, Luigia Elzi, Jan Fehr, Jacques Fellay, Hansjakob Furrer, Christoph A. Fux, Meri Gorgievski, Huldrych F. Günthard, David Haerry, Barbara Hasse, Hans H. Hirsch, Matthias Hoffmann, Irène Hösli, Christian R. Kahlert, Laurent Kaiser, Olivia Keiser, Thomas Klimkait, Roger D. Kouyos, Helen Kovari, Bruno Ledergerber, G Martinetti, Begoña Martínez de Tejada, Catia Marzolini, Karin J. Metzner, Nicolas Müller, David Nadal, Dunja Nicca, G Pantaleo, Andri Rauch, Stephan Regenass, Christoph Rudin, F. Schöni-Affolter, Patrick Schmid, R Speck, M Stöckle, Philip Tarr, Alexandra Trkola, Pietro Vernazza, Rainer Weber, Sabine Yerly, Mark van der Valk, Suzanne E. Geerlings, Abraham Goorhuis, Joppe W. Hovius, B. Lempkes, F.J.B. Nellen, T. van der Poll, Jan M. Prins, Peter Reiss, Michèle van Vugt, W. Joost Wiersinga, F.W.M.N. Wit, Marlies van Duinen, J. van Eden, A. Hazenberg, A M H van Hes, F J J Pijnappel, S Smalhout, Annouschka M. Weijsenfeld, Suzanne Jurriaans, Nicole Back, Hans L. Zaaijer, Ben Berkhout, Marion Cornelissen, C. Schinkel, Katja C. Wolthers, Edgar J.G. Peters, Michiel A. van Agtmael, Reshma Autar, Marije K. Bomers, Kim Sigaloff, M. Heitmuller, Liedewij Laan, C. Wim Ang, Robin van Houdt, Marcel Jonges, TW Kuijpers, Dasja Pajkrt, H. J. Scherpbier, Carla de Boer, A. van der Plas, Maarten van den Berge, Arjan Stegeman, S. Baas, L. Hage de Looff, A. G. M. Buiting, Anne Q. Reuwer, Jacobien Veenemans, Bas Wintermans, M.J.H. Pronk, Heidi S. M. Ammerlaan, D. N. J. van den Bersselaar, E. S. de Munnik, Birgit Deiman, A Jansz, Volkher Scharnhorst, Jeroen H. T. Tjhie, M.C.A. Wegdam, Arne van Eeden, Jeannine F. Nellen, W. Brokking, Loek J.M. Elsenburg, H. Nobel, M.E.E. van Kasteren, Marvin A. H. Berrevoets, A.E. Brouwer, Alexander Adams, R. van Erve, B.A.F.M. de Kruijf-van de Wiel, S. Keelan-Phaf, B. van de Ven, B. van der Ven, A. G. M. Buiting, J.L. Murck, T.E.M.S. de Vries-Sluijs, Hannelore I. Bax, Eric C. M. Van Gorp, N. C. de Jong-Peltenburg, Martim Melo, Els van Nood, Jan Nouwen, Bart Rijnders, Casper Rokx, Carolina A. M. Schurink, Lennert Slobbe, Annelies Verbon, N. Bassant, J. E. A. van Beek, M. Vriesde, L.M. van Zonneveld, Joris R. de Groot, Charles A. Boucher, Marion Koopmans, Jeroen J. A. van Kampen, Pieter L. A. Fraaij, Annemarie M. C. van Rossum, Clementien L. Vermont, Linda C. van der Knaap, Eric J. W. Visser, Judith Branger, Renée A. Douma, A.S. Cents-Bosma, C.J.H.M. Duijf-van de Ven, Emile F. Schippers, Cees van Nieuwkoop, J M van IJperen, J. Geilings, G. van der Hut, Nathalie D. van Burgel, Eliane M.S. Leyten, L. B. S. Gelinck, Femke Mollema, S. Davids-Veldhuis, C. Tearno, G.S. Wildenbeest, E. Heikens, P. H. P. Groeneveld, J.W. Bouwhuis, A. J. J. Lammers, S. Kraan, A. G. W. van Hulzen, M.S.M. Kruiper, G.L. van der Bliek, Petra Bor, S. B. Debast, Gertjan H.J. Wagenvoort, Frank P. Kroon, Mark de Boer, H. Jolink, Merel M. C. Lambregts, Anna H.E. Roukens, Henk Scheper, W. Dorama, Natasja van Holten, Eric C. J. Claas, Els Wessels, Jan G. den Hollander, Rachida el Moussaoui, Katalin Pogány, C.J. Brouwer, Jesper Smit, D. Struik-Kalkman, T.G.C.M. van Niekerk, Oscar Pontesilli, S.H. Lowe, Astrid M. L. Oude Lashof, Dirk Posthouwer, Marlies E van Wolfswinkel, Robin Ackens, Kristina Burgers, J. Schippers, B. Weijenberg-Maes, Inge H. M. van Loo, Thomas Havenith, Marit G. A. van Vonderen, Linda M. Kampschreur, S. M. Faber, R. Steeman-Bouma, A. Al Moujahid, G. J. Kootstra, C. E. Delsing, Matthijs Plas, L. Scheiberlich, W. Kortmann, G. van Twillert, R. Renckens, D. Ruiter-Pronk, F.A. van Truijen-Oud, J. W. T. Cohen Stuart, E.R. Jansen, Marieke Hoogewerf, Wouter Rozemeijer, Wil A. van der Reijden, J. C. Sinnige, Kees Brinkman, G.E.L. van den Berk, W. L. Blok, Kamilla D. Lettinga, Marina de Regt, W.E.M. Schouten, Janneke E. Stalenhoef, Jan A. Veenstra, S.M.E. Vrouenraets, H. Blaauw, G.F. Geerders, M.J. Kleene, Marc R. Kok, M. Knapen, I.B. van der Meché, E. Mulder-Seeleman, A.J.M. Toonen, S. Wijnands, E. Wttewaal, David Kwa, Reinout van Crevel, Koen van Aerde, Anthonius S. M. Dofferhoff, S. S. V. Henriet, H.J.M. ter Hofstede, Jacobien J. Hoogerwerf, Monique Keuter, Olivier Richel, M. Albers, Karin J. T. Grintjes-Huisman, M. de Haan, M. Marneef, R. Strik-Albers, Janette Rahamat‐Langendoen, Foekje F. Stelma, David M. Burger, Elisabeth H. Gisolf, Robert‐Jan Hassing, Mark A. A. Claassen, G. ter Beest,
We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred nine individuals with this variant had a 0.54 to 0.74 log 10 increase (i.e., a ~3.5-fold to 5.5-fold increase) in viral load compared with, and exhibited CD4 cell decline twice as fast as, 6604 individuals with other subtype-B strains. Without treatment, advanced HIV—CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences—is expected to be reached, on average, 9 months after ...
American Association for the Advancement of Science
Helen Kovari, Caroline Sabin, Bruno Ledergerber, Lene Ryom, Peter Reiss, Matthew Law, Christian Pradier, François Dabis, Antonella d’Arminio Monforte, Colette Smith, Stéphane De Wit, Ole Kirk, Jens Lundgren, Rainer Weber, William G. Powderly, N. Shortman, Christiane Moecklinghoff, G. Reilly, Xavier Franquet, Camilla I. Hatleberg, Lene Ryom, Caroline Sabin, Daniella Kamara, Colette Smith, A. Phillips, Amanda Mocroft, Anders Bojesen, Jens Nielsen, Charles E. Matthews, David Raben, Jens Lundgren, Rikke Salbøl Brandt, Martin Rickenbach, Iuri Fanti, Eric Krum, M Hillebregt, S. Geffard, Jaohar Mourabi, Anders Sundström, M Delforge, Éric Fontas, Ferrán Torres, Hamish McManus, Seth Wright, Jesper Kjær, Anette Sjøl, P. Meidahl, J. Helweg-Larsen, Johan Iversen, Lene Ryom, Amanda Mocroft, Ole Kirk, Peter Reiss, Michael J. Ross, Christoph A. Fux, P. Morlat, Olivier Moranne, Anouk M Kesselring, David A Kamara, Colette Smith, Jens Lundgren, Colette Smith, Lene Ryom, A. Phillips, Rainer Weber, P. Morlat, Christian Pradier, Peter Reiss, Nina Friis‐Møller, Justyna D. Kowalska, Jens Lundgren, Caroline Sabin, Matthew Law, Antonella d’Arminio Monforte, François Dabis, Mathias Bruyand, Peter Reiss, Colette Smith, David A Kamara, Mark Bower, Gerd Fätkenheuer, Andrew E. Grulich, Lene Ryom, Jens Lundgren, Peter Reiss, S Zaheri, M Hillebregt, Luuk Gras, Jan M. Prins, Taco W. Kuijpers, H. J. Scherpbier, Jan T. M. van der Meer, F.W.M.N. Wit, Mieke H. Godfried, Peter Reiss, T. van der Poll, F.J.B. Nellen, J Lange, Suzanne E. Geerlings, M. van Vugt, Dasja Pajkrt, J. C. Bos, Marc van der Valk, Marlous L. Grijsen, W. Joost Wiersinga, Abraham Goorhuis, Joppe W. Hovius, S.H. Lowe, Astrid Oude Lashof, Dirk Posthouwer, M.J.H. Pronk, Heidi S. M. Ammerlaan, M.E. van der Ende, T.E.M.S. de Vries-Sluijs, Carolina A. M. Schurink, Jan Nouwen, Annelies Verbon, Bart Rijnders, Eric C. M. Van Gorp, M. van der Feltz, Gertjan J. A. Driessen, Annemarie M. C. van Rossum, Judith Branger, Emile F. Schippers, Cees van Nieuwkoop, E. P. van Elzakker, P. H. P. Groeneveld, J.W. Bouwhuis, Robert Soetekouw, Reinier W. ten Kate, Frank P. Kroon, Jaap T. van Dissel, Sandra M. Arend, Mark de Boer, H. Jolink, Hans Vollaard, Martijn P. Bauer, Jan G. den Hollander, Katalin Pogány, G. van Twillert, W. Kortmann, J. W. T. Cohen Stuart, B. M. W. Diederen, Eliane M.S. Leyten, L. B. S. Gelinck, G. J. Kootstra, Corine E. Delsing, K. Brinkman, Willem L. Blok, P. H. J. Frissen, W.E.M. Schouten, G.E.L. van den Berk, M.E.E. van Kasteren, A.E. Brouwer, Jan A. Veenstra, Kamilla D. Lettinga, Jan W. Mulder, S.M.E. Vrouenraets, Fanny N. Lauw, Arne van Eeden, D. W. M. Verhagen, Herman G. Sprenger, R. A. Doedens, Elisabeth H. Schölvinck, Sander van Assen, Wouter F.W. Bierman, P.P. Koopmans, Monique Keuter, André van der Ven, H.J.M. ter Hofstede, A. S. M. Dofferhoff, Adilia Warris, Reinout van Crevel, A. I. M. Hoepelman, Tania Mudrikova, Michael Schneider, Pauline M. Ellerbroek, Jan Jelrik Oosterheert, J.E. Arends, M.W.M. Wassenberg, Roos E. Barth, Michiel A. van Agtmael, R.M. Perenboom, Frans A.P. Claessen, Marije K. Bomers, Edgar J.G. Peters, Sibyl P. M. Geelen, Tom F.W. Wolfs, Louis Bont, Claudia Richter, J.P. van der Berg, Elisabeth H. Gisolf, Maarten van den Berge, Arjan Stegeman, Marit G. A. van Vonderen, D P F van Houte, Sebastiaan Weijer, Rachida el Moussaoui, Chris Winkel, Faj Muskiet, Robin M. Voigt, Fidéline Bonnet-Serrano, François Dabis, Fidéline Bonnet-Serrano, S. Bouchet, Dominique Breilh, Geneviève Chêne, François Dabis, M. Dupon, H. Fleury, Valérie Gaborieau, D. Lacoste, Denis Malvy, P. Mercié, P. Morlat, D. Neau, Isabelle Pellegrin, JL Pellegrin, Sandrine Reigadas, S. Tchamgoué, Mathias Bruyand, Geneviève Chêne, François Dabis, Catherine Fagard, S. Lawson‐Ayayi, Laura Richert, Rodolphe Thiébaut, L. Wittkop, Keila Magalhães André, Fidéline Bonnet-Serrano, N. Bernard, L. Caunègre, C. Cazanave, J. Ceccaldi, I. Chossat, C Courtault, F. Dauchy, S Witte, D. Dondia, M. Dupon, A. Dupont, P. Duffau, H. Dutronc, Sophie Farbos, I. Faure, Valérie Gaborieau, Y Gérard, C. Greib, M. Hessamfar-Joseph, Yoannis Imbert, D. Lacoste, P. Lataste, Estibaliz Lazaro, Denis Malvy, J. Marie, M. Méchain, JP. Meraud, P. Mercié, É. Monlun, P. Morlat, D. Neau, Anthony Ochoa, JL Pellegrin, M. Pillot-Debelleix, Thierry Pistone, Iona Raymond, M. C. Receveur, P Rispal, L. Sorin, S. Tchamgoué, C Valette, M.A. Vandenhende, MO. Vareil, Jean‐François Viallard, H. Wille, Grégory J. Wirth, J.F. Moreau, Isabelle Pellegrin, H. Fleury, M.E. Lafon, Sandrine Reigadas, Pascale Trimoulet, S. Bouchet, Dominique Breilh, Françoise Haramburu, G. Miremont-Salamé, M.J. Blaizeau, I. Crespel, M. Decoin, Sandrine Delveaux, F. Diarra, C d'Ivernois, C. Hanappier, D. Lacoste, S. Lawson‐Ayayi, Olivier Leleux,
Abstract Background. Although human immunodeficiency virus (HIV)-positive persons on antiretroviral therapy (ART) frequently have chronic liver enzyme elevation (cLEE), the underlying cause is often unclear. Methods. Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study participants without chronic viral hepatitis were observed to the earliest of cLEE (elevated aminotransferase ≥6 months), death, last follow-up, or January 2, 2014. Antiretroviral treatment exposure was categorized as follows: ...
Oxford University Press
Foni Le Brun‐Ricalens, Hartwig Löhr, François Valotteau, Jehanne Affolter,
Deux artefacts en silex remarquables, tant d’un point de vue lithologique que typologique, ont été découverts en prospection dans le bassin mosellan ; l’un au Luxembourg sur un plateau gréseux, l’autre en Allemagne sur une basse terrasse de la Moselle près de la ville de Trèves. Par leur morphologie singulière, les deux éléments retouchés, l’un de grandes dimensions, l’autre plus petit, sont caractéristiques des éléments de «faucille » en demi-lune de type Altheim. L’exemplaire recueilli à Lintgen au ...
Tópico(s): Archaeology and ancient environmental studies
2013 - French Prehistoric Society | Bulletin de la Société préhistorique de France
Nathalie Satta, Sabrina Pagano, Fabrizio Montecucco, Bariş Gencer, François Mach, Laurent Kaiser, Alexandra Calmy, Nicolas Vuilleumier, Vincent Aubert, Julia M. I. Barth, Manuel Battegay, Enos Bernasconi, J Böni, H C Bucher, Claudine Burton‐Jeangros, Alexandra Calmy, Matthias Cavassini, Matthias Egger, Luigia Elzi, Jan Fehr, Jacques Fellay, P Francioli, Hansjakob Furrer, Christoph A. Fux, Meri Gorgievski, Huldrych F. Günthard, David Haerry, Barbara Hasse, Hans H. Hirsch, Bernard Hirschel, Irène Hösli, Christian R. Kahlert, Laurent Kaiser, Olivia Keiser, Christian Kind, Thomas Klimkait, Helen Kovari, Bruno Ledergerber, G Martinetti, Begoña Martínez de Tejada, Karin J. Metzner, Nicolas Müller, David Nadal, G Pantaleo, Andri Rauch, Stephan Regenass, Martin Rickenbach, Christoph Rudin, Patrick Schmid, D. Schultze, F. Schöni-Affolter, Jörg Schüpbach, Roberto F. Speck, Patrick Taffé, Philip Tarr, A. Telenti, Alexandra Trkola, Pietro Vernazza, Roger Weber, Sabine Yerly,
Objectives To determine the existence of autoantibodies against apolipoprotein A-1 (anti-apoA-1 IgG) in HIV patients and explore their association with biological features of HIV infection and different inflammatory biomarkers. We also evaluated their impact on CD4+ lymphocytes survival. Methods Anti-apoA-1 IgG plasma levels were assessed by ELISA in 237 HIV positive patients from a national prospective cohort with no current lipid-lowering therapy. Results 58% of patients were found positive for ...
Tópico(s): Systemic Lupus Erythematosus Research
2017 - Elsevier BV | Journal of Infection
Jos Akkermans, Anthony McDonnell, Jana Retkowsky, Kristine A. Kuhn, Lorenz Affolter, Chloé Brassart, Jana Retkowsky, Ultan Sherman, Jos Akkermans, Ronan Carbery, Paul Jansen, Anthony McDonnell, Michael Morley, Sanne Nijs, François Pichault, Daniel Spurk, Caroline Straub,
... Management Presenter: Chloé Brassart; U. of Liège Presenter: Francois Pichault; U. of Liege Gig Work Challenges and Work Alienation: Hindering Factors for Living a Calling? Presenter: Lorenz Affolter; - Presenter: Daniel Spurk; U. of Bern Presenter: Caroline ...
Tópico(s): Transportation and Mobility Innovations
2022 - Academy of Management | Academy of Management Proceedings
Paul Fernandes, Jean‐Paul Raynal, Pascal Tallet, Christophe Tufféry, Michel Piboule, Micheline Séronie-Vivien, Marie‐Roger Séronie‐Vivien, Alain Turq, André Morala, Jehanne Affolter, Dominique Millet, Françoise Millet, Frédéric Bazile, Patrick Schmidt, Pascal Foucher, Vincent Delvigne, Jérémie Liagre, Stéphane Gaillot, Alexandre Morin, Marie‐Hélène Moncel, Jean-François Garnier, Céline Léandri-Bressy,
Une carte des principales formations à silex du sud de la France est en cours de réalisation. Elle propose, à tous les préhistoriens, une base nécessaire au développement d'études interrégionales sur la circulation des silex. Elle est le fruit d'une collaboration entre des acteurs impliqués dans la problématique de caractérisation de la provenance des silex. Elle regroupe les résultats de leurs prospections systématiques ou ciblées dans six régions (Aquitaine, Auvergne, Languedoc-Roussillon, Midi- ...
2013 - | Paléo
Erich S. Tusch, Lene Ryom, Annegret Pelchen‐Matthews, Amanda Mocroft, Daniel Elbirt, Cristiana Oprea, Huldrych F. Günthard, Cornelia Staehelin, Robert Zangerle, Isabelle Suárez, Jörg Janne Vehreschild, Ferdinand Wit, Marianna Menozzi, Antonella d'Arminio Monforte, Vincenzo Spagnuolo, Christian Pradier, Christina Carlander, Paula Suanzes, Jan‐Christian Wasmuth, Andrew Carr, Kathy Petoumenos, Frauke Borgans, Fabrice Bonnet, Stéphane De Wit, Wafaa El‐Sadr, Bastian Neesgaard, Nadine Jaschinski, Lauren Greenberg, Sean R Hosein, Joel E. Gallant, Vani Vannappagari, Lital Young, Caroline Sabin, Jens Lundgren, Lars Peters, Joanne Reekie, W El-Sadr, Gino Calvo, Fidéline Bonnet-Serrano, F Dabis, Ole Kirk, A Mocroft, Matthew Law, Antonella d’Arminio Monforte, Linda Morfeldt, C Pradier, P Reiss, Raimar Weber, S. De Wit, A Lind-Thomsen, Rikke Salbøl Brandt, M Hillebreght, S Zaheri, Ferdinand W N M Wit, Alexandra Scherrer, F. Schöni-Affolter, Martin Rickenbach, Alessandro Tavelli, Iuri Fanti, Olivier Leleux, J. Mourali, Fabien Le Marec, Eloïse Boerg, Eva Thulin, Anders Sundström, Georg Bartsch, G Thompsen, Coca Necsoi, M Delforge, Éric Fontas, C Caissotti, K Dollet, S Mateu, Ferrán Torres, Kathy Petoumenos, A Blance, Robin Huang, Rainer Puhr, Kamilla Grønborg Laut, Daniel Tuyet Kristensen, Caroline Sabin, Andrew Phillips, David A Kamara, Colette Smith, A Mocroft, Camilla Ingrid Hatleberg, A Lind-Thomsen, Rikke Salbøl Brandt, David Raben, Charles E. Matthews, Anders Bojesen, Anne Louise Grevsen, Jens Lundgren, Lene Ryom, William G. Powderly, N. Shortman, Christiane Moecklinghoff, Gerry Reilly, Xavier Franquet, Lene Ryom, A Mocroft, Ole Kirk, Peter Reiß, Colette Smit, M Ross, C A Fux, P. Morlat, E Fontas, David A Kamara, Colette Smith, Jens Lundgren, Colette Smith, Lene Ryom, Camilla Ingrid Hatleberg, A. N. Phillips, Richard D Weber, P Morlat, C Pradier, Peter Reiss, F W N M Wit, Nina Friis‐Møller, Justyna D. Kowalska, Jens Lundgren, Caroline Sabin, Lene Ryom, Camilla Ingrid Hatleberg, Matthew Law, Antonella d’Arminio Monforte, F Dabis, Fidéline Bonnet-Serrano, Peter Reiß, Ferdinand W N M Wit, Colette Smith, David A Kamara, Julia Bohlius, Mark Bower, G Fätkenheuer, Andrew E. Grulich, Jens Lundgren, Anette Sjøl, P. Meidahl, J-G. Iversen, Central P Reiss, S Zaheri, M Hillebregt, F W N M Wit, Jan M. Prins, TW Kuijpers, H. J. Scherpbier, Jan T. M. van der Meer, Ferdinand W N M Wit, Mieke H. Godfried, Peter Reiß, T. van der Poll, F.J.B. Nellen, Suzanne E. Geerlings, Michèle van Vugt, Dasja Pajkrt, Jeannet C. Bos, W. Joost Wiersinga, Marc van der Valk, Abraham Goorhuis, Joppe W. Hovius, J. van Eden, A. Henderiks, A M H van Hes, M Mutschelknauss, H. Nobel, F J J Pijnappel, Suzanne Jurriaans, Nicole Back, Hans L. Zaaijer, Ben Berkhout, Marion Cornelissen, C. Schinkel, X V Thomas, Admiraal De Ruyter Ziekenhuis, Maarten van den Berge, Arjan Stegeman, S. Baas, L. Hage de Looff, Donald J. Versteeg, Catharina Ziekenhuis, M.J.H. Pronk, Heidi S. M. Ammerlaan, E. S. de Munnik, A R Jansz, Jeroen H. T. Tjhie, M.C.A. Wegdam, Birgit Deiman, Volkher Scharnhorst, A. van der Plas, Annouschka M. Weijsenfeld, Marc van der Valk, T.E.M.S. de Vries-Sluijs, Eric C. M. Van Gorp, Carolina A. M. Schurink, Jan Nouwen, Annelies Verbon, Bart Rijnders, Hannelore I. Bax, M. van der Feltz, N. Bassant, J. E. A. van Beek, M. Vriesde, L.M. van Zonneveld, A de Oude-Lubbers, H J van den Berg-Cameron, F B Bruinsma-Broekman, Joris R. de Groot, M de Zeeuw- de Man, Charles A. Boucher, Marion Koopmans, Jeroen J. A. van Kampen, Suzan D. Pas, Erasmus MC–Sophia, Gertjan J. A. Driessen, Annemarie M. C. van Rossum, Linda C. van der Knaap, Eline G. Visser, Judith Branger, A Rijkeboer-Mes, C.J.H.M. Duijf-van de Ven, Haga Ziekenhuis, Emile F. Schippers, Cees van Nieuwkoop, J M van IJperen, J. Geilings, G. van der Hut, Paul Franck, Arne van Eeden, W. Brokking, Marco R. de Groot, L. Elsenburg, M. Damen, I S Kwa, P. H. P. Groeneveld, J.W. Bouwhuis, Julia F. van den Berg, A. G. W. van Hulzen, G.L. van der Bliek, Petra Bor, Peter Bloembergen, M. J. H. M. Wolfhagen, G J H M Ruijs, Frank P. Kroon, Mark de Boer, Marlies Bauer, H. Jolink, Albert M. Vollaard, W Dorama, Natasja van Holten, Eric C. J. Claas, Els Wessels, Jan G. den Hollander, Katalin Pogány, Anna H.E. Roukens, M Kastelijns, J.V. Smit, Erasmus Smit, D. Struik-Kalkman, C. Tearno, M. Bezemer, T.G.C.M. van Niekerk, Oscar Pontesilli, S.H. Lowe, Astrid M. L. Oude Lashof, Dirk Posthouwer, Robin Ackens, J. Schippers, R Vergoossen, B. Weijenberg-Maes, Inge H. M. van Loo, Thomas Havenith, Eliane M.S. Leyten, L. B. S. Gelinck, A van Hartingsveld, C Meerkerk, G.S. Wildenbeest, J. A. E. M. Mutsaers, C. Jansen, Jan W. Mulder, S.M.E. Vrouenraets, Fanny N. Lauw, Michelle Broekhuizen, H Paap, D J Vlasblom, Paul H.M. Smits, M C Zuiderzee, Sebastiaan Weijer, Rachida el Moussaoui, A S Bosma, Marit G. A. van Vonderen, D P F van Houte, Linda M. Kampschreur, Kyra L. Dijkstra,
Abstract Background Mortality among people with human immunodeficiency virus (HIV) declined with the introduction of combination antiretroviral therapy. We investigated trends in mortality in people with HIV from 1999 through 2020. Methods Data were collected from the Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) cohort between January 1999 through January 2015 and the International Cohort Consortium of Infectious Disease (RESPOND) from October 2017 through December 2020. Age-standardized ...
Oxford University Press
... Saadaoui M. Sambrani N. Hudry B. Pradel J. Affolter M. Graba Y. A unique extradenticle recruitment mode ...
Tópico(s): Animal Genetics and Reproduction
2007 - Elsevier BV | Developmental Cell