Petra El Hajj, David Gilot, Mélodie Migault, Anne Theunis, Léon C.L.T. van Kempen, François Salès, Hussein Fayyad‐Kazan, B. Badran, Denis Larsimont, Ahmad Awada, Laura Bachelot, M.D. Galibert, G. Ghanem, Fabrice Journé,
We previously demonstrated an inverse correlation between tyrosinase-related protein 1 (TYRP1) mRNA expression in melanoma metastases and patient survival. However, TYRP1 protein was not detected in half of tissues expressing mRNA and did not correlate with survival. Based on a study reporting that 3′ untranslated region (UTR) of TYRP1 mRNA contains two miR-155-5p (named miR-155) binding sites exhibiting single-nucleotide polymorphisms (SNPs) that promote (matched miRNA–mRNA interaction) mRNA decay or ...
Tópico(s): Antimicrobial Peptides and Activities
2015 - Springer Nature | British Journal of Cancer
Caroline Migault, Delphine Lebrun, O Toubas, Yohan N’Guyen, Aurélien Giltat, Julien Gautier, D. Toubas, François Lebargy, Alain Delmer, Firouzé Bani‐Sadr,
Idelalisib is a potent and selective inhibitor of the PI3Kδ approved since September 2014 for the treatment of several types of B cell malignancies. Pulmonary adverse events related to idelalisib are an emerging serious adverse event. We report here a single centre cohort of 16 patients who initiated idelalisib as routine treatment. Five of them experienced severe pulmonary adverse events related to idelalisib therapy. Comparison of the 5 patients with severe pulmonary events versus the 11 patients ...
Tópico(s): Lymphoma Diagnosis and Treatment
2018 - Taylor & Francis | Journal of Chemotherapy
Pierre Pradat, Pascal Puglièse, Isabelle Poizot‐Martin, Marc‐Antoine Valantin, Lise Cuzin, Jacques Reynes, Eric Billaud, Thomas Huleux, Firouzé Bani‐Sadr, David Rey, A. Frésard, Christine Jacomet, Claudine Duvivier, Antoine Chéret, Laurent Hustache‐Mathieu, Bruno Hoën, André Cabié, Laurent Cotte, Laurent Cotte, Christian Chidiac, Tristan Ferry, Florence Ader, F. Biron, A. Boibieux, P. Miailhes, T. Perpoint, I. Schlienger, John Lippmann, Elisabeth Braun, J. Koffi, Christophe Longuet, V. Guéripel, C. Augustin-Normand, C. Brochier, S Degroodt, P. Puglièse, C. Ceppi, Éric Cua, Jacqueline Cottalorda, Johan Courjon, P. Dellamonica, Élisa Demonchy, Anne De Monte, J. Durant, C Etienne, Stephen J. Ferrando, J.G. Fuzibet, R. Garraffo, A. Joulié, Karine Risso, V. Mondain, A. Naqvi, N. Oran, I. Perbost, Stéphane Pillet, B Prouvost-Keller, S Wehrlen-Pugliese, E. Rosenthal, S. Sausse, V. Rio, P.-M. Roger, Sylvie Brégigeon, Olivia Zaegel‐Faucher, V. Obry‐Roguet, M Orticoni, M J Soavi, P Geneau de Lamarlière, Hélène Laroche, E. Ressiot, Mauro Giovanni Carta, M.J. Ducassou, Ingrid Jacquet, S. Gallie, Anne Galinier, A.S. Ritleng, A Ivanova, Carla Blanco-Betancourt, C. Lions, C. Debreux, V. Obry‐Roguet, Isabelle Poizot‐Martin, Rachid Agher, Christine Katlama, Marc‐Antoine Valantin, Claudine Duvivier, O. Lortholary, Fanny Lanternier, Caroline Charlier, C. Rouzaud, Claire Aguilar, Bonnie Henry, David Lebeaux, G. Cessot, Anna Gergely, Paul‐Henri Consigny, F. Touam, C Louisin, Marco Antonio Álvarez, N. Biezunski, Lise Cuzin, Alexa Debard, Pierre Delobel, Cyrille Delpierre, C. R. Fourcade, B. Marchou, Guillaume Martin‐Blondel, M. Porte, M Mularczyk, D. Garipuy, Karine Sauné, I. Lepain, M. Marcel, E. Puntis, N. Atoui, Marie-Laure Casanova, V. Faucherre, Jeanne‐Marie Jacquet, V. Le Moing, Alain Makinson, Corinne Merle De Boever, A Montoya Ferrer, Christina Psomas, Jacques Reynes, F. Raffi, Clotilde Allavena, Eric Billaud, Charlotte Biron, B. Bonnet, S. Bouchez, D. Boutoille, C. Brunet, T Jovelin, Nancy Hall, C. Bernaud, P Morineau, Véronique Reliquet, O Aubry, P Point, M. Besnier, L Larmet, H Hüe, S. Pineau, Elisabeth André‐Garnier, A. Rodallec, Ph. Choisy, S. Vandame, T. Huleux, F. Ajana, I. Alcaraz, V. Baclet, T. Huleux, H. Melliez, N. Viget, M. Valette, E. Aïssi, Ch. Allienne, Agnès Meybeck, Bertrand Riff, Firouzé Bani‐Sadr, C. Rouger, J. Berger, Yohan N’Guyen, D. Lambert, I. Kmiec, Maxime Hentzien, Delphine Lebrun, Caroline Migault, D. Rey, M.L. Batard, Claudine Bernard-Henry, Geneviève Chêne, E de Mautort, Patricia Fischer, M Partisani, M. Priester, F. Lucht, A. Frésard, Élisabeth Botelho-Nevers, Amandine Gagneux‐Brunon, C. Cazorla, C. Guglielminotti, F. Daoud, Martin Lutz, Christine Jacomet, H. Laurichesse, O. Lesens, M. Vidal, Natacha Mrozek, V. Corbin, C. Auméran, Olivier Baud, S. Casanova, Dilek Çoban, Laurent Hustache‐Mathieu, M.C. Thiebaut-Drobacheff, Adeline Foltzer, V. Gendrin, F Bozon, C Chirouze, Sylvie Abel, André Cabié, Raymond Césaire, G. Dos Santos, Laurence Fagour, Fatiha Najioullah, M. Ouka, S. Pierre-François, Mathilde Pircher, B. Rozé, Bruno Hoën, Rachida Ouissa, I. Lamaury,
Direct-Acting Antivirals (DAAs) opened a new era in HCV treatment. We report the impact of HCV treatment in French HIV-HCV coinfected patients.All HIV-HCV patients from the Dat'AIDS cohort followed between 2012 and 2015 were included. HCV status was defined yearly as naive, spontaneous cure, sustained virological response (SVR12), failure or reinfection.Among 32,945 HIV-infected patients, 15.2% were positive for anti-HCV antibodies. From 2012 to 2015, HCV incidence rate increased from 0.35%PY to 0. ...
Tópico(s): Liver Disease Diagnosis and Treatment
2017 - Elsevier BV | Journal of Infection