Guillaume Martin‐Blondel, Anne‐Geneviève Marcelin, Cathia Soulié, Sofia Kaisaridi, Clovis Lusivika‐Nzinga, Karen Zafilaza, Céline Dorival, Laura Nailler, Anaïs Boston, Anne‐Marie Ronchetti, Cléa Melenotte, André Cabie, Christophe Choquet, Albert Trinh-Duc, Karine Lacombe, Géraldine Gaube, François Coustillères, Valérie Pourcher, Jean-Philippe Martellosio, Nathan Peiffer-Smadja, Marie Chauveau, P Housset, Lionel Piroth, Mathilde Devaux, Gilles Pialoux, Aurélie Martin, Vincent Dubée, Jérôme Frey, Audrey Le Bot, Charles Cazanave, Philippe Petua, Roland Liblau, Fabrice Carrat, Youri Yordanov,
Our aim was to compare the clinical and virological outcomes in Omicron BA.1- and BA.2-infected patients who received sotrovimab with those in patients who received nirmatrelvir for the prevention of severe COVID-19.In this multi-centric, prospective ANRS 0003S CoCoPrev cohort study, patients at a high risk of progression of mild-to-moderate BA.1 or BA.2 COVID-19 who received sotrovimab or nirmatrelvir were included. The proportion of patients with progression to severe COVID-19, time between the ...
Tópico(s): SARS-CoV-2 detection and testing
2022 - Elsevier BV | Clinical Microbiology and Infection
Helia Robert‐Ebadi, Philippe Robin, Olivier Hügli, Franck Verschuren, Albert Trinh-Duc, Pierre‐Marie Roy, Jeannot Schmidt, Thierry Fumeaux, Guy Meyer, Daniel Hayoz, Pierre‐Nicolas Carron, Pierre‐Yves Salaün, François Sarasin, Olivier Rutschmann, Grégoire Le Gal, Marc Righini,
... MD Olivier Hugli, MD Franck Verschuren, MD Albert Trinh-Duc, MD Pierre-Marie Roy, MD Jeannot Schmidt, MD Thierry Fumeaux, MD Guy Meyer, MD Daniel Hayoz, MD Pierre-Nicolas Carron, MD Pierre-Yves Salaun, MD François Sarasin, MD Olivier Rutschmann, MD Grégoire Le Gal, ...
Tópico(s): Diagnosis and Treatment of Venous Diseases
2021 - Lippincott Williams & Wilkins | Circulation
Guillaume Martin‐Blondel, Anne‐Geneviève Marcelin, Cathia Soulié, Sofia Kaisaridi, Clovis Lusivika‐Nzinga, Céline Dorival, Laura Nailler, Anaïs Boston, Cléa Melenotte, André Cabie, Christophe Choquet, François Coustillères, Jean-Philippe Martellosio, Géraldine Gaube, Albert Trinh-Duc, Anne‐Marie Ronchetti, Valérie Pourcher, Marie Chauveau, Karine Lacombe, Nathan Peiffer-Smadja, P Housset, Aurore Perrot, Gilles Pialoux, Aurélie Martin, Vincent Dubée, Mathilde Devaux, Jérôme Frey, Charles Cazanave, Roland Liblau, Fabrice Carrat, Youri Yordanov,
Tópico(s): Respiratory viral infections research
2022 - Elsevier BV | Journal of Infection
Jessica Dennis, Alejandra Medina-Rivera, Vinh Trương, Lina Antounians, Nora Zwingerman, Giovana Carrasco, Lisa Strug, Philip S. Wells, France Trégouët, France Morange, M Wilson, France Gagnon, Pierre Albaladejo, Marc Samama, Piérre Siè, Sophie Kauffmann, Vincent Mémier, Pierre Suchon, Alain Viallon, Jean David, Y Gruel, Lorenn Bellamy, Emmanuel de Maistre, Pauline Romegoux, Sophie Thoret, Gilles Pernod, Jean-Luc Bosson, E. V. Bazin, Nicolas Combaret, A.‐L. CHERPRENET, Moustafa Fares, Sophie Dufraisse, Vincent Minville, Pierre‐Emmanuel Morange, Marc Léone, William Cohen, Nadège Néant, Raphaël Marlu, Françoise Carpentier, Pascal Defaye, Patrick Mismetti, Serge Molliex, Julien Lanoiselée, Vincent Piriou, Carine Delaleu-Rague, M. Lefèvre, Sophie Lagrange, L. Ardillon, Yves Ozier, Julien Bovet, A. Steib, Sonia Mebaouj, Louis Profumo, Stéphanie Roullet, David M. Smadja, Guy Meyer, Didier Journois, Albert Trinh-Duc, Thibault Viard, Loïc Belle, Albrice Levrat, Etienne Gautheron, Frédéric Heluwaert, S. Schlumberger, Antonia Blanié, Dan Benhamou, Claire Flaujac, Nadia Rosencher, Hélène Beloeil, Catherine Blery, Lauren Daviet, Pierre Guéret, David Faraoni, Jean‐François Schved, Pauline Deras, Samir Jaber, Pierre Yves Gueugniaud, Bernard Floccard, Karim Asehnoune, Jérôme Paulus, Omar Amrani, Marie Caroline Gonthier, Marie Geneviève Huisse, Julien Josserand, Emmanuelle de Raucourt, Cécile Defournel, Yohann Dubois, S. Bouvier, P.M. Roy, Sigismond Lasocki, Christian Carmagnac, Catherine Chastagner, J.M. Thouret, M.-A. Sevestre, Eric Meaudre, Pierre‐Julien Cungi, Sophie Susen, Jean Yves Lefrant, Stéphane Macey, J. Rieu, Anne Godiér,
The use of prothrombin complex concentrates and the role of plasma concentration of anticoagulants in the management of bleeding in patients treated with direct oral anticoagulants are still debated. Our aim was to describe management strategies and outcomes of severe bleeding events in patients treated with direct oral anticoagulants.We performed a prospective cohort study of 732 patients treated with dabigatran, rivaroxaban, or apixaban hospitalized for severe bleeding, included prospectively ...
Tópico(s): Acute Myocardial Infarction Research
2017 - Lippincott Williams & Wilkins | Anesthesiology
Stéphane Zuily, Benjamin Lefèvre, Olivier Sanchez, Ombeline Empis de Vendin, Guillaume de Ciancio, Jean‐Benoît Arlet, Lina Khider, Béatrice Terriat, Hélène Greigert, Céline Robert, Guillaume Louis, Albert Trinh-Duc, P Rispal, Sandrine Accassat, Guillaume Thiéry, David Montani, R. Azarian, Nicolas Méneveau, Simon Soudet, Raphaël Le Mao, F. Maurier, Vincent Le Moing, I. Quéré, Cécile Yelnik, Nicolas Lefèbvre, M. Martinot, Maxime Delrue, Y. Benhamou, Florence Parent, Pierre‐Marie Roy, Émilie Presles, François Goehringer, Patrick Mismetti, Laurent Bertoletti, Patrick Rossignol, Françis Couturaud, Denis Wahl, Nathalie Thilly, Silvy Laporte, Stéphane Zuily, Françis Couturaud, François Goehringer, Silvy Laporte, Patrick Mismetti, Émilie Presles, Patrick Rossignol, Nathalie Thilly, Denis Wahl, Thomas Lecompte, Emmanuel Oger, Marie‐Antoinette Sevestre, Florence Parent, Y. Benhamou, Pierre‐Marie Roy, Tristan Gigante, Morgane Gilg, Pierre-Luc Maclot, Bénédicte Rossignol, Jonathan Udot, H Bouteille, Andréa Buchmuller, Céline Peurière, El Mehdi Siaghy, Valérie Bouaziz, Charlotte Daguin, B Grosjean, Véronique Saunier, Laurence Verger, M. Jacquot, Nadine Petitpain, Martin Charly, Laurent Tordella, Émilie Presles, Guillaume Baronnet, Elisabeth Baux, Athanase Bénétos, Jean-Baptiste Blanvillain, Marie Conrad, Guilhem Courte, Aurélie Cravoisy-Popovic, Virginie Dufrost, Sébastien Gibot, Philippe Guerci, Laure Joly, Antoine Kimmoun, Matthieu Koszutski, Alexandrine Larue, Bruno Lévy, Marie-Reine Losser, Mathieu Mattèi, Lionel Nace, Emmanuel Novy, Pierre Perez, Jean-Pierre Pertek, Camille Rigaux, Alexis Sauvage, Évelyne Schvoerer, Carine Thivilier, Lev Volkov, Piotr Zieminski, Manil Benlounes, Charles C. K. Cheng, Jean-Baptiste de Fréminville, Grégoire Detriche, Emmanuel Flammarion, Guillaume Goudot, Amer Cavalheiro Hamdan, Raphaël Hindré, Corina Manoli, E. Messas, Adrien Michon, Tristan Mirault, Jean Pastré, Marie-Aude Penet, Benjamin Planquette, Geoffroy Volle, Rémy Hamdan, Aline Laubriet-Jazayeri, Vincent Petit, Lionel Piroth, Jean‐Pierre Quenot, Mélissa Saccu, Damien Barraud, Zoé Cavalli, Rostane Gaci, Mathilde Andreu, Laurent Bertoletti, Andréa Buchmuller, Élodie De Magalhaes, Sophie Bulifon, Athénaïs Boucly, Nathan Ebstein, Marc Humbert, Xavier Jaïs, Mitja Jevnikar, Laurent Savale, Andrei Seferian, Charlotte Colin, Timothée Ganem, Mehdi Roumila, Romain Chopard, Matthieu Besutti, B. Mouhat, C. Andréjak, S. Dupas, Gaëlle Le Roy, Santhi Samy-Modeliar, Anne Coste, Alexandre Fauché, David Goetghebeur, Christophe Gut-Gobert, Clément Hoffmann, Baptiste Hourmant, Cécile L'hévéder, Emmanuelle Lemoigne, Olivier Nepveu, Raphaël Paret, Gaël Picart, Saïd Azerkan, C Boudaa, J. Campagne, Peter Eszto, B. Godbert, Jean-François Guichard, Marion Heschung, Antoine Legoff, J. Mariot, Pascale Martin, Magalie Mercy, Julie Perrin, Stéphane Raymond, N. Vernier, Pierre Fesler, Pierrick Henneton, Cédric Mercuzot, Nathalie Pansu, Lucas Perez, Loïc Andre, E Bakhache, Marie‐Charlotte Chopin, Marie Gilbert, M. Lambert, Mohammad Ryadh Pokeerbux, François Danion, Yves Hansmann, Estelle Rougier, Yvon Ruch, Dominique Stéphan, Axel Ursenbach, Isabelle Connerade, Simon Gravier, D. Kayser, Jean-Marc Michel, Mahsa Mohseni, Waël Younes, Ruxandra Burlacu, Amanda Lopes, Stéphane Mouly, Kladoum Nassarmadji, D. Sène, Virginie Siguret, Alain Stepanian, Cédric Annweiler, Antoine Brangier, Vincent Dubée, Samir Henni, Jeanne Hersant, Jocelyne Loison, Léa Kern, Jean-Baptiste Laine, Claire Neveux-Brecheteau, Lucia Perez, Ruben Benaïnous, B. Giroux-Leprieur, Marilucy Lopez‐Sublet, Saïda Khaled-Jousselin, Yohann Bernard, Amélie Amiot, Jessica Breistroff, Emilie Detry, Kadidiatou Diallo, A Didier, Nathalie Dumont, Julie Egensperger, A. Emmerich, Nelly François, F Gallo, Valérie George, Quentin Gérome, Aurélie Gutehrle, Laure Lehman, Séverine Petit, Vanessa Piard, Maximilien Saint-Gilles, Olivier Terenzi, Amélie Marquette, Hélène Mortelette, Mathilde Audry, Amélie Cransac, Marine Maillard, A. Boyer, Floriana Gallo, Arielle Urbing, Imane Zahaf, Alexandra Byczko, Amina Chaalal, Georgette Berlier, Corinne Bernabe, Souad Bezzeghoud, Caroline Chaudier, Carole Chauvet, M. Davier, Carine Labruyère, Estelle Perrin, Michael St.Pierre, Claire-Annissa Chekirine, Florence Voivret, Ramdane Meftali, O Ahmad Sabri, Anaïs Beulaygue, Julie Gall, Laure Girard, Soumia Haddaoui, Scheherazade Rami, Auriane Couderc, Aude Le Breton, Marie-Line Perruche, Cindy Claudon, Ludivine Roussel, Aude Barnier, Tiphaine Blanchard, Bénédicte Le Gall, Mélanie Pelouin, A Veillon, Quam Aquereburu, Charlène Delaygue, Zahoua Ait Idir, Jérémy Drugeon, Déborah Dubrulle, Rabah Tezkratt, Anne‐Sophie Frantz, Julie Drouaine, Jacqueline Dubois, Magali Eyriey, Elina Haerrel, Mélinda Beaudenon, Mialy Guenet, Thibaud Lecerf, Stéphanie Marechal-Girault, Sami Rehaiem, Romain Simon, Florence Dangeul-Potier, Morgane Goulvent, Souha Fliss, Fadhila Messani, Béatrice Mizejewski,
Venous thromboembolism is a major complication of coronavirus disease 2019 (COVID-19). We hypothesized that a weight-adjusted intermediate dose of anticoagulation may decrease the risk of venous thromboembolism COVID-19 patients.In this multicenter, randomised, open-label, phase 4, superiority trial with blinded adjudication of outcomes, we randomly assigned adult patients hospitalised in 20 French centers and presenting with acute respiratory SARS-CoV-2. Eligible patients were randomly assigned ( ...
Elsevier BV
Jean-Paul Guillet, C. Role, A. Trinh Duc, Arnaud François,
Due to increased anthropogenic activities in recent decades, many heavy metal elements have been emitted into the atmosphere and transported to remote regions. The Enrichment factors (EFs) is a normally used method for evaluating the source of heavy metal elements. However, because of some flaws of this method (e.g., higher solubility of heavy metals elements than reference elements in dilute acid), the anthropogenic contributions of some heavy metal elements in the precipitation sample were overestimated. ...
Tópico(s): Radioactivity and Radon Measurements
1987 - Pergamon Press | European Journal of Cancer and Clinical Oncology
Emmanuel Montassier, François Javaudin, Farès Moustafa, Demeno Nandjou, Maxime Maignan, Jean-Benoît Hardouin, Caroline Annoot, Maja Ogielska, Pascal-Louis Orer, T. Schotté, J. Bouget, Syamak Agha Babaei, Pierre-Alexis Raynal, Antoine Eche, Albert Trinh Duc, R. Cojocaru, Nesrine Benaouicha, G. Potel, Éric Batard, David A. Talan,
Study objective Efforts to reduce unnecessary and unnecessarily long antibiotic treatment for community-acquired pneumonia have been attempted through use of procalcitonin and through guidelines based on serial clinical assessment. Our aim is to compare guideline-based clinical assessment– and procalcitonin algorithm–guided antibiotic use among patients with community-acquired pneumonia. Methods We performed a pragmatic, randomized, multicenter trial from November 2012 to April 2015 at 12 French ...
Tópico(s): Nosocomial Infections in ICU
2019 - Elsevier BV | Annals of Emergency Medicine
François Gueyffier, Pascal Piedbois, Jean‐François Bergmann, Bernard Avouac, Thomas Borel, Rémy Boussageon, Catherine Brun-Strang, David Braunstein, Béatrice Cazeneuve, Marine Diviné, P. Dufour, Nicolas Girerd, Valérie Laigle, Claire Le Jeunne, François Liard, Amélie Marsot, Jean‐Louis Montastruc, Albert Trinh-Duc, Éric Vicaut,
Estimating net benefit makes possible to clarify the basis for therapeutic decisions on an individual and collective level. This clarification is a must in shared medical decision-making and evidence-based medicine. Numerous methods are available, although none outweigh the others. The complex specifications of net benefit estimation should be tailored to the expectations of the central stakeholder, patient or society, and the unlimited range of potential contexts. The challenges, limitations, constraints ...
Tópico(s): Clinical practice guidelines implementation
2017 - Elsevier BV | Therapies
J.‐J. Lefrère, François Paquez, A. Trinh Duc, P. Rouger, Ch. Salmon,
Cette étude est basée sur un entretien avec 31 sujets reconnus séropositifs contre le virus de l'immunodéficience humaine (VIH) à l'occasion d'un récent don de sang. Le lieu du don, le type de donneur, le facteur de risque ont été établis. Des questions ont porté sur l'utilisation du don comme test diagnostique et la notion d'une auto-exclusion écrite ou orale avant le don. La majorité des sujets présentaient un facteur de risque d'infection par le VIH ; la majorité avait donné pour le test sérologique. ...
Tópico(s): HIV, Drug Use, Sexual Risk
1990 - Elsevier BV | Revue Francaise de Transfusion et d& apos Hémobiologie
François Gueyffier, Pascal Piedbois, Jean‐François Bergmann, Bernard Avouac, Thomas Borel, Rémy Boussageon, Catherine Brun-Strang, David Braunstein, Béatrice Cazeneuve, Marine Diviné, P. Dufour, Nicolas Girerd, Valérie Laigle, Claire Le Jeunne, François Liard, Amélie Marsot, Jean‐Louis Montastruc, Albert Trinh-Duc, Éric Vicaut,
L’estimation du bénéfice net permet d’expliciter les fondements des décisions thérapeutiques, individuelles et collectives. Cette explicitation est une exigence dans la décision médicale partagée et la pratique de la médecine factuelle ou evidence-based medicine. De nombreuses méthodes existent, sans qu’aucune ne puisse s’imposer face à un cahier des charges complexe et devant s’ajuster à l’attente de l’acteur central, le patient ou la société, et à un éventail infini des contextes possibles. Les ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2017 - Elsevier BV | Therapies
Timothée Bruel, Lou-Léna Vrignaud, Françoise Porrot, Isabelle Staropoli, Delphine Planas, Florence Guivel‐Benhassine, Julien Puech, Matthieu Prot, Sandie Munier, William Bolland, Cathia Soulié, Karen Zafilaza, Clovis Lusivika‐Nzinga, Marie-Laure Meledge, Céline Dorival, Diana Molino, Hélène Péré, Youri Yordanov, Etienne Simon‐Lorière, David Veyer, Fabrice Carrat, Olivier Schwartz, Anne‐Geneviève Marcelin, Guillaume Martin‐Blondel, Magalie Garcia, Valentin Giraud, Agathe Metais, Fance Cazenave-Roblot, Jean-Philippe Martellosio Anne-Marie Ronchetti, Thomas Gabas, Naima Hadjadj, Célia Salanoubat, Amélie Chabrol, P Housset, Agathe Pardon, Anne‐Laure Faucon, Valérie Caudwell, L Liblau, Laurent Alric, G. Pugnet, M. Mourguet, Eva Bories, Delphine Bonnet, Sandrine Charpentier, Pierre Delobel, Alexa Debard, Colleen Beck, X. Boumaza, Stella Rousset Fanny Lanternier, Claire Delage, Elisabete Gomes Pires, Morgane Cheminant, N. Chauvin, Xavier Eyer Véronique Delcey Simon Bessis, Mélanie Cresta, Romain Gueneau Pélagie Thibaut, Marine Nadal, Martin Siguier, Marwa Bachir, Christia Palacios Valérie Pourcher, Cléa Melenotte, Antoine Fayçal, V. Bérot, C. Brin, Siham Djebara, Karen Zafilaza, Stéphane Marot, Sophie Sayon, Vincent Leducq, Isabelle Malet, Elisa Teyssou, Adélie Gothland Karine Lacombe, Yasmine Abi Aad, Thibault Chiarabini, Raynald Feliho, Nadia Valin, Fabien Brigant, Julien Boize, Pierre‐Clément Thiebaud, Marie Moreau, Charlotte Billard Nathalie De Castro, Geoffroy Liégeon, Blandine Denis, Jean‐Michel Molina, Lucia Etheve André Cabié, Sylvie Abel, Ornella Cabras, K Guitteaud, Sandrine Pierre- François Vincent Dubee, Diama Ndiaye, Jonathan Pehlivan, Michael Phelippeau, Rafael Mahieu Alexandre Duvignaud, Thierry Pistone, Arnaud Desclaux, D. Neau, Charles Cazanave Jean-François Faucher, Benjamin Festou, Magali Dupuy-Grasset, V. Loustaud‐Ratti, Delphine Chainier Nathan Peiffer- Smadja, Christophe Choquet, O. Da Conceiçao, Michaël Thy, Lio Collas, C. Godard, Donia Bouzid, Vittiaroat Ing, Laurent Pereira, Thomas Pavlowsky, Camille RavautAntoine Asquier-Khati, D. Boutoille, Marie Chauveau, Colin Deschanvres, F Bot, M. Cailleaux, François Bénézit, Anne Maillard, B. Hue, Pierre Tattevin François Coustilleres, Claudia Carvalho-Schneider, Simon Jamard, Laëticia Petit, Karl Stefic Natacha Mrozek, Clément Theis, M. Vidal, Léo Sauvat, Delphine Martineau Benjamin Lefèvre, Guillaume Baronnet, Agnès Didier Florence Ader, Thomas Perpoint, Anne Conrad, Paul Chabert, Pierre Chauvelot Aurélie Martin, Paul Loubet, Julien Mazet, Romaric Larcher, Didier Laureillard Mathilde Devaux Jérôme Frey, Amos Woerlen, Aline Remillon, Laure Absensur-Vuillaume, Pauline Bouquet Albert Trinh-Duc, Patrick Rispal Philippe Petua, Julien Carillo Aurore Perrot, K. Delavigne, P. Cougoul, Jérémie Dion, Odile Rauzy Mathieu Blot, Thibault Sixt, Florian Moretto, Carole Charles, Lionel Piroth Sophie Circosta, Lydia Leger, A. Arulananthan, Carine Lascoux, Pascaline Valérie, Leia Becam Yazdan Yazdanpanah, Ventzislava Petrov–Sanchez, Alpha Diallo, Soizic Le Mestre, Guillaume Le Meut Isabelle Goderel, Frédéric Chau, Brahim Soltana, Jessica Chane Tang, Jérémie Guedj, Yvanie Caillé,
Antibodies effective against the recent Omicron sublineages are missing. By taking advantage of a multi-centric prospective cohort of immunocompromised individuals treated for mild-to-moderate COVID-19, Bruel et al. show that administration of 500 mg of sotrovimab induces serum neutralization and antibody-dependent cellular cytotoxicity of BQ.1.1 and XBB.1.5. Therefore, sotrovimab may remain a therapeutic option against these variants. Antibodies effective against the recent Omicron sublineages ...
Tópico(s): Immunotherapy and Immune Responses
2023 - Elsevier BV | Med