Claudio Toniolo, Gian Maria Bonora, Vincenzo Barone, Alfonso Bavoso, Ettore Benedetti, Benedetto Di Blasio, P. Grimaldi, Francesco Lelj, Vincenzo Pavone, Carlo Pedone,
... Alfonso Bavoso, Ettore Benedetti, Benedetto Di Blasio, Patrizio Grimaldi, Francesco Lelj, Vincenzo Pavone, and Carlo PedoneCite this: Macromolecules ...
Tópico(s): Analytical Chemistry and Chromatography
1985 - American Chemical Society | Macromolecules
Francesco Raimondi, Teresa Ferrara, Letizia Capasso, Maria Sellitto, Francesca Landolfo, Antonia Romano, Ernesto Grimaldi, Francesco Scopacasa,
... MD Division of Neonatology Department of Pediatrics Ernesto Grimaldi, MD Francesco Scopacasa, MD Department of Biochemistry and Medical Biotechnology ...
Tópico(s): Streptococcal Infections and Treatments
2010 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
M. Carla Aragoni, Massimiliano Arca, Francesco Demartin, F.A. Devillanova, Alessandra Garau, P. Grimaldi, Francesco Isaia, Francesco Lelj, Vito Lippolis, G. Verani,
Abstract The reaction between 1,3‐dimethyl‐4‐imidazoline‐2‐selone ( 2 ) and ICN gave the adduct 2· ICN, whose crystal structure features dimers made up of two [ 2· CN] + and two I − which strongly interact. Hybrid DFT calculations on the adduct 2· ICN, on the cation [ 2· CN] + , and on the dimer ( 2· ICN) 2 account for a partially hypervalent selenium atom in 2· ICN and for the observed structural features. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Tópico(s): Inorganic Chemistry and Materials
2004 - Wiley | European Journal of Inorganic Chemistry
Pietro Iaffaldano, Emilio Portaccio, Giuseppe Lucisano, Marta Simone, Alessia Manni, Tommaso Guerra, Damiano Paolicelli, Matteo Betti, Ermelinda De Meo, Luisa Pastò, Lorenzo Razzolini, Maria A. Rocca, Laura Ferrè, Vincenzo Brescia Morra, Francesco Patti, Mauro Zaffaroni, Claudio Gasperini, Giovanna De Luca, Diana Ferraro, Franco Granella, Carlo Pozzilli, Silvia Romano, Paolo Gallo, Roberto Bergamaschi, Maria Gabriella Coniglio, Giacomo Lus, Marika Vianello, Paola Banfi, Alessandra Lugaresi, Rocco Totaro, Daniele Spitaleri, Eleonora Cocco, Franco Di Palma, Davide Maimone, Paola Valentino, Valentina Torri Clerici, Alessandra Protti, Giorgia Teresa Maniscalco, Giuseppe Salemi, Ilaria Pesci, Umberto Aguglia, Vito Lepore, Massimo Filippi, Maria Trojano, Maria Pia Amato, Elisabetta Ferraro, Francesco Logullo, Girolama Alessandra Marfia, Roberto Bombardi, Davide Nasuelli, Paolo Bellantonio, Milena De Riz, Paola Gazzola, Guido Cavaletti, Matilde Inglese, Antonella Conte, Gioacchino Tedeschi, Alessia Di Sapio, Alessandro Leone, Sara Montepietra, Bruno Marini, Maurizia Gatto, Maria Sessa, Maria Teresa Ferrò, Augusto Rini, Daniela Cargnelutti, Massimiliano Mirabella, Alessandro P. Burlina, Carlo Avolio, Paola Cavalla, Marco Rovaris, Bonaventura Ardito, Carlo Piantadosi, Paolo Confalonieri, Raffaella Clerici, Silvia Strumia, Francesca De Robertis, R. Quatrale, Leonardo Sinisi, Cristina Fioretti, Vincenzo Di Lazzaro, Sebastiano Bucello, Luca Mancinelli, Giuseppe Ribizzi, Roberto Ignazio Zarbo, Luigi Grimaldi, Francesco Corea, Vincenzo Sidoti, Luca Massacesi, Roberto Balgera, Marcello Romano, Francesco D'Andrea, Anna Luisa Ancona, Matteo Pizzorno, Steno Rinalduzzi, Francesco Passantino, Lorenzo Capone, Marta Bianchi, Simonetta Venturi, Giuseppe Trivelli, Giampaolo Brichetto, Silvia Fermi, Placido Bramanti, Rosa Iodice, Maria Luisa Piras, Maria Grazia Celani, Paolo Barone, Tiziana Tassinari, A. Marson, Marinella Clerico, Paola Banfi, Claudio Solaro,
Importance Although up to 20% of patients with multiple sclerosis (MS) experience onset before 18 years of age, it has been suggested that people with pediatric-onset MS (POMS) are protected against disability because of greater capacity for repair. Objective To assess the incidence of and factors associated with progression independent of relapse activity (PIRA) and relapse-associated worsening (RAW) in POMS compared with typical adult-onset MS (AOMS) and late-onset MS (LOMS). Design, Setting, and Participants ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2023 - American Medical Association | JAMA Neurology
Yi Qin, Milad Ashrafizadeh, Vera Mongiardini, Benedetto Grimaldi, Francesco Crea, Katja Rietdorf, Balázs Győrffy, Daniel J. Klionsky, Jun Ren, Wei Zhang, Xianbin Zhang,
The emergence of drug resistance is a major challenge for oncologists. Resistance can be categorized as acquired or intrinsic; the alteration of several biological mechanisms contributes to both intrinsic and acquired resistance. Macroautophagy/autophagy is the primary process in eukaryotes for the degradation of macromolecules and organelles. This process is critical in maintaining cellular homeostasis. Given its function as either a pro-survival or a pro-death phenomenon, autophagy has a complex ...
Tópico(s): Calcium signaling and nucleotide metabolism
2023 - Elsevier BV | Cancer Letters
Alberto Grimaldi, Francesco Demetrio Minuto, Alessandro Perol, Silvia Casagrande, Andrea Lanzini,
Energy storage systems are becoming one of the most relevant technologies to effectively support renewable energy source (RES) deployment at large. The present work proposes a detailed ageing and energy analysis based on a data-driven empirical approach of a real utility-scale grid-connected lithium-ion battery energy storage system (LIBESS) for providing power grid services. The system under investigation is an operative utility-scale LIBESS integrated with a multi-MW PV plant and connected to the ...
Tópico(s): Electric Vehicles and Infrastructure
2023 - Elsevier BV | Journal of Energy Storage
Mariafrancesca Hyeraci, Elena Sofia Papanikolau, M Grimaldi, Francesco Ricci, Sabatino Pallotta, Rosanna Monetta, Ylenia Aura Minafò, Giovanni Di Lella, Giovanna Galdo, Damiano Abeni, Luca Fania, Elena Dellambra,
Non-melanoma skin cancers (NMSCs), which include basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and actinic keratosis (AK), are the most common cancer diseases in the Caucasian race. If diagnosed late and improperly treated, BCC and SCC can become locally advanced and metastasize. Malignant melanoma (MM) is less frequent but more lethal than NMSC. Given the individual and social burdens of skin cancers, performing an adequate prevention is needed. Ultraviolet (UV) ray exposure is one of the ...
Tópico(s): Nonmelanoma Skin Cancer Studies
2023 - Multidisciplinary Digital Publishing Institute | Biomolecules
Antonio Grimaldi, Francesco Panariello, Patrizia Annunziata, Teresa Giuliano, Michela Daniele, Biancamaria Pierri, Chiara Colantuono, Marcello Salvi, Valentina Bouché, Anna Manfredi, Maria Concetta Cuomo, Denise Di Concilio, Claudia Tiberio, Mariano Fiorenza, Giuseppe Portella, Ilaria Cimmino, Antonio Sorrentino, Giovanna Fusco, Maria Rosaria Granata, Pellegrino Cerino, Antonio Limone, Luigi Atripaldi, Andrea Ballabio, Davide Cacchiarelli,
Abstract Background Genomic surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only approach to rapidly monitor and tackle emerging variants of concern (VOC) of the COVID-19 pandemic. Such scrutiny is crucial to limit the spread of VOC that might escape the immune protection conferred by vaccination strategies or previous virus exposure. It is also becoming clear now that efficient genomic surveillance would require monitoring of the host gene expression to identify ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - BioMed Central | Genome Medicine
Emanuele D’Amico, Aurora Zanghì, Mariangela Sciandra, Roberta Lanzillo, Graziella Callari, Antonio Cortese, Giacomo Lus, Matteo Lucchini, Maria Buccafusca, Simona Bonavita, Antonio Gallo, Erica Curti, Alberto Gajofatto, Elisabetta Signoriello, Alvino Bisecco, Francesca Gobbin, Maria Teresa Ferrò, Gina Ferrazzano, Maddalena Sparaco, Paola Valentino, Massimiliano Mirabella, Franco Granella, Vincenzo Brescia Morra, Luigi Maria Grimaldi, Francesco Patti, Giovanna Borriello, Paola Grossi, Antonio Carotenuto, Ernesto Siena, Elena Tsantes, Alessia Giugno, Gianmarco Abbadessa, Clara Grazia Chisari,
Tópico(s): Herpesvirus Infections and Treatments
2020 - Springer Science+Business Media | Journal of Neurology
Valentina Parisi, Laura Petraglia, Vittoria D’Esposito, Serena Cabaro, Giuseppe Rengo, Aurelio Caruso, Maria Grimaldi, Francesco Baldascino, Antonio De Bellis, Dino Franco Vitale, Roberto Formisano, Adele Ferro, Stefania Paolillo, Laurent Davin, Patrizio Lancellotti, Pietro Formisano, Pasquale Perrone Filardi, Nicola Ferrara, Dario Leosco,
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2018 - Elsevier BV | International Journal of Cardiology
Domenico Luca Carní, Domenico Grimaldi, Francesco Lamonaca, Libero Nigro, Paolo F. Sciammarella,
Recently the technological advances have allowed the introduction of new standards to model and monitor control systems. The classical distributed measurement systems (DMSs) have been enriched with the use of a large number of new measurement devices, increasing the amount of produced data. New paradigms for their management are needed, that coupled with actuators, enable the integration of DMSs into more complex systems, known as Cyber-Physical Systems (CPSs). CPSs application field includes different ...
Tópico(s): Scientific Computing and Data Management
2017 - Research Institute of Intelligent Computer Systems | International Journal of Computing
Benedetta Gui, Anna Lia Valentini, Valeria Ninivaggi, Maura Miccò, Viola Zecchi, Pier Paolo Grimaldi, Francesco Cambi, Maurizio Guido, Lorenzo Bonomo,
ndometriosis is a systemic disease that affects about 10% to 20% of women during their reproductive age, characterized by the presence of endometrial glands and stroma outside the uterine cavity (1).Endometriosis lesions are characterized by intralesional recurrent bleeding during menses, because of the hormonal responsiveness of ectopic endometrial tissue, with resulting fibrosis.Typical symptoms are cyclic or chronic pelvic pain, dysmenorrhea, dyspareunia, and pain during defecation or urinating. ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2017 - | Diagnostic and Interventional Radiology
Alessandro Cimarello, Carlo N. Grimaldi, Francesco Mariani, Michele Battistoni, Massimo Dal Re,
Tópico(s): Advanced Combustion Engine Technologies
2017 - | SAE technical papers on CD-ROM/SAE technical paper series
Valentina Parisi, Giuseppe Rengo, Pasquale Perrone Filardi, Gennaro Pagano, Grazia Daniela Femminella, Stefania Paolillo, Laura Petraglia, Giuseppina Gambino, Aurelio Caruso, Maria Grimaldi, Francesco Baldascino, Maria Nolano, Andrea Elia, Alessandro Cannavò, Antonio De Bellis, Enrico Coscioni, Teresa Pellegrino, Alberto Cuocolo, Nicola Ferrara, Dario Leosco,
It has been reported that epicardial adipose tissue (EAT) may affect myocardial autonomic function.The aim of this study was to explore the relationship between EAT and cardiac sympathetic nerve activity in patients with heart failure.In 110 patients with systolic heart failure, we evaluated the correlation between echocardiographic EAT thickness and cardiac adrenergic nerve activity assessed by (123)I-metaiodobenzylguanidine ((123)I-MIBG). The predictive value of EAT thickness on cardiac sympathetic ...
Tópico(s): Cardiovascular Effects of Exercise
2016 - Lippincott Williams & Wilkins | Circulation Research
Antonio M. Grimaldi, Francesco M. Marincola, Paolo A. Ascierto,
Introduction: The advent of new immunotherapies for the treatment of metastatic melanoma has resulted in various novel combination strategies. Because of their distinct modes of action, different immunotherapies have been investigated in combination with one another, as well as combined with targeted therapies and other treatment modalities.Areas covered: Anti-CTLA-4 and anti-PD-1 treatments enhance antitumor immunity through complementary and non-redundant mechanisms. The combination of the anti- ...
Tópico(s): Immunotherapy and Immune Responses
2015 - Taylor & Francis | Expert Opinion on Biological Therapy
Vincenzo Grimaldi, Francesco Paolo Mancini, Amelia Casamassimi, Mohammed Al‐Omran, Alberto Zullo, Teresa Infante, Claudio Napoli,
Cardiovascular disease is the leading cause of morbidity and mortality in the world. In recent years, there has been an increasing interest both in basic and clinical research regarding the field of cell therapy for coronary heart disease (CHD). Several preclinical models of CHD have suggested that regenerative properties of stem and progenitor cells might help restoring myocardial functions in the event of cardiac diseases. Here, we summarize different types of stem/progenitor cells that have been ...
Tópico(s): Congenital heart defects research
2013 - Elsevier BV | Journal of Cardiology
Michele Battistoni, Carlo N. Grimaldi, Francesco Mariani,
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2012 - | SAE technical papers on CD-ROM/SAE technical paper series
Pablo Ingelmo, Rossella Parini, Marco Grimaldi, Francesco Mauri, Matteo Romagnoli, Giovanna Tagliabue, Marta Somaini, Emre Sahillioğlu, Geoff Frawley,
Accumulation of glycosaminoglycans is known to cause significant problems in the anesthetic management of children with mucopolysaccharidoses (MPS). Clinical and standard radiological evaluation may convey insufficient information about the upper airway and trachea in children with MPS. Multidetector computed tomography (MDCT) images have been used to define the central airway and previous studies have recommended this tool to assess the airway of children who are considered at risk of difficult intubation. ...
Tópico(s): Tracheal and airway disorders
2011 - Edizioni Minerva Medica | Minerva Anestesiologica
Michele De Bonis, Maurizio Taramasso, Antonio Grimaldi, Francesco Maisano, Maria Calabrese, Alessandro Verzini, David Ferrara, Ottavio Alfieri,
To assess the results of the three-dimensional (3D)-shaped GeoForm ring for the treatment of functional mitral regurgitation (FMR).Seventy-four patients with severe FMR and systolic dysfunction underwent GeoForm ring implantation. Forty-six patients (62%) were in the New York Heart Association (NYHA) class III-IV. Concomitant procedures were coronary artery bypass grafting (CABG) (33 patients (pts)), tricuspid repair (23 pts), atrial fibrillation ablation (20 pts), aortic valve replacement (eight pts) and ...
Tópico(s): Cardiovascular Function and Risk Factors
2011 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Michele Ceccarelli, A. Speranza, Domenico Grimaldi, Francesco Lamonaca,
This paper reports a novel method for nucleus and micronucleus segmentation. These biological structures are useful to biologists for relieving structural chromosome aberration. The adopted method consists of a pipeline of advanced computer vision algorithms, some of them were specifically tailored for the current segmentation problem. Starting from the weak hypotheses on size, shape, and color of micronucleus, it is possible to efficiently segment and measure the image features of interest by a ...
Tópico(s): Immunotherapy and Immune Responses
2010 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Instrumentation and Measurement
Daniela Grimaldi, Francesco Nonino, Sabina Cevoli, Alberto Vandelli, Roberto D’Amico, Pietro Cortelli,
Tópico(s): Trigeminal Neuralgia and Treatments
2009 - Springer Science+Business Media | Journal of Neurology
Michele De Bonis, Elisabetta Lapenna, Flavia Sorrentino, Giovanni La Canna, Antonio Grimaldi, Francesco Maisano, Lucia Torracca, Ottavio Alfieri,
To assess the evolution of tricuspid regurgitation (TR) in dilated cardiomyopathy (DCM) patients submitted to mitral repair for functional mitral regurgitation (MR).Ninety-one DCM patients (mean age 61+/-11.3) submitted to MV repair (+/-tricuspid repair) for functional MR were included. Preoperative EF was 30.9+/-6.5%, left ventricular (LV) end-diastolic volume 113+/-31.5 ml/m(2), LV end-systolic volume 81.8+/-26.7 ml/m(2), functional MR > or =3+/4+. TR was classified as < or =1+/4+ in 57 patients (62.6%), 2+/4+ ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2008 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Pasquale Gallo, Michael V.G. Latronico, Paolo Gallo, Séréna Grimaldi, Francesco Borgia, Matilde Todaro, Philip Jones, Paola Gallinari, Raffaele De Francesco, Gennaro Ciliberto, Christian Steinkühler, Giovanni Esposito, Gianluigi Condorelli,
AimsRecent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the control of cardiac gene expression. Specific histone deacetylases (HDACs) can, in fact, play a positive or negative role in determining cardiac myocyte (CM) size. Here, we report on the effect on hypertrophy development of three inhibitors (HDACi) of class I HDACs.
Tópico(s): Protein Degradation and Inhibitors
2008 - Oxford University Press | Cardiovascular Research
Domenico Luca Carní, Domenico Grimaldi, Francesco Lamonaca,
This paper presents a method that detects and corrects alterations of 1, exposure; 2, out-of-focus; and 3, Gaussian noise affecting, contemporaneously, the images that are acquired in flow cytometer measurement devices. These alterations reduce image quality and interfere with correct micronucleus (MN) detection in a lymphocyte. The objectives of the proposed correction are given as follows: 1, to correctly process the image with the pattern-matching algorithm in order to detect the MN in human lymphocytes; ...
Tópico(s): Single-cell and spatial transcriptomics
2007 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Instrumentation and Measurement
Gianluca Tettamanti, Annalisa Grimaldi, Francesco Pennacchio, Magda de Eguileor,
Programmed cell death (PCD) is crucial in body restructuring during metamorphosis of holometabolous insects (those that have a pupal stage between the final larval and adult stages). Besides apoptosis, an increasing body of evidence indicates that in several insect species programmed autophagy also plays a key role in these developmental processes. We have recently characterized the midgut replacement process in Heliothis virescens larva, during the prepupal phase, responsible for the formation of ...
Tópico(s): Mosquito-borne diseases and control
2007 - Taylor & Francis | Autophagy
Salvatore Grimaldi, Francesco Serinaldi,
Abstract A design hyetograph is a synthetic rainfall temporal pattern associated with a return period, usually determined by means of statistical analysis of observed mean rainfall intensity through intensity—duration—frequency (IDF) curves. Since the univariate approach is simple to apply and data availability is scarce, only the mean intensity of a rainfall storm is usually analysed statistically. The other characteristics of a rainfall storm, such as peak (maximum intensity), total depth and duration, ...
Tópico(s): Financial Risk and Volatility Modeling
2006 - Taylor & Francis | Hydrological Sciences Journal
M. Carla Aragoni, Massimiliano Arca, F.A. Devillanova, P. Grimaldi, Francesco Isaia, Francesco Lelj, Vito Lippolis,
Abstract The reactions between L=E donors [L: 1,3‐dimethylimidazolyl framework; E: S ( 1 ), Se ( 2 )] and halogens X 2 (X: Cl, Br, I) to form either “T‐shaped” hypervalent chalcogen (TY) or linear charge‐transfer‐type adducts (CT) have been studied in the density functional theory (DFT) context by considering both thermodynamic and kinetic aspects. Apart from the case of the adducts between sulfur donors and diiodine, hypervalent compounds are calculated to be always more stable than CT ones in the gas phase, in ...
Tópico(s): Crystallography and molecular interactions
2006 - Wiley | European Journal of Inorganic Chemistry
Gianluca Aimaretti, Maria Rosaria Ambrosio, Carolina Di Somma, Maurizio Gasperi, Salvatore Cannavò, Carla Scaroni, Alessandra Fusco, Patrizia Del Monte, Ernesto De Menis, Marco Faustini‐Fustini, Franco Grimaldi, Francesco Logoluso, Paola Razzore, Silvia Rovere, Salvatore Benvenga, Ettore C. degli Uberti, Laura De Marinis, Gaetano Lombardi, Franco Mantero, Enio Martino, Giulio Giordano, Ezio Ghigo,
Abstract Context: Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are conditions at high risk for the development of hypopituitarism. Objective: The objective of the study was to clarify whether pituitary deficiencies and normal pituitary function recorded at 3 months would improve or worsen at 12 months after the brain injury. Design and Patients: Pituitary function was tested at 3 and 12 months in patients who had TBI (n = 70) or SAH (n = 32). Results: In TBI, the 3-month evaluation had ...
Tópico(s): Adrenal Hormones and Disorders
2005 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Salvatore Grimaldi, Francesco Serinaldi, Francesco Napolitano, Lucio Ubertini,
A design hyetograph is a synthetic rainfall temporal pattern associated with a return period. Usually it is determined by means of statistical analysis of observed rainfall mean intensity through intensity-duration-frequency (IDF) curves. The other characteristics of a rainfall event, such as the peak, total depth and duration, are found indirectly throughout several phases of hydrological analysis, and trigger suitable work assumptions. The aim of this paper is to apply a multivariate approach in ...
Tópico(s): Image and Signal Denoising Methods
2005 - International Association of Hydrological Sciences | IAHS-AISH publication
Salvatore Grimaldi, Francesco Serinaldi,
The univariate flood frequency analysis is widely used in hydrological studies. Often only flood peak or flood volume is statistically analyzed. For a more complete analysis the three main characteristics of a flood event i.e. peak, volume and duration are required. To fully understand these variables and their relationships, a multivariate statistical approach is necessary. The main aim of this paper is to define the trivariate probability density and cumulative distribution functions. When the ...
Tópico(s): Climate variability and models
2005 - Elsevier BV | Advances in Water Resources