Clara Grilo, Pablo M. Lucas, Alberto Fernández‐Gil, Ma José Fernández Seara, Gonçalo Ferrão da Costa, Sara Roque, Helena Rio‐Maior, Mónia Nakamura, Francisco Álvares, Francisco Petrucci‐Fonseca, Eloy Revilla,
Abstract Despite severe population declines and an overall range contraction, some populations of large carnivores have managed to survive in human‐modified landscapes. From a conservation perspective, it is important to identify the factors allowing for this coexistence, including the relevant habitat characteristics associated with the presence of large carnivores. We evaluated the role of several environmental factors describing habitat quality for wolves Canis lupus in the humanised Iberian ...
Tópico(s): Animal Behavior and Welfare Studies
2018 - Wiley | Animal Conservation

Flávia Galindo Silvestre, Cibele Soares de Castro, Juliana de Moura, Mário S. Giusta, Mário de María, Éder S. S. Álvares, Francisco Carlos Faria Lobato, Ronnie Antunes de Assis, L.A. Gonçalves, Ida Cristina Gubert, Carlos Chávez-Olórtegui, Evanguedes Kalapothakis,
Accidents caused by brown spiders (Loxosceles genus) are frequent in Brazil and are associated with dermonecrotic lesions and, eventually, systemic reactions that may be lethal. The major species implicated with human envenoming have been: L. intermedia, L. gaucho and L. laeta. In this study we characterized the venom from Loxosceles similis, a species of spider normally found inside caves. L. similis venom was characterized by two-dimensional gel electrophoresis and enzymatic activity (dermonecrosis ...
Tópico(s): Healthcare and Venom Research
2005 - Elsevier BV | Toxicon
Nádia Conceição‐Neto, João R. Mesquita, Mark Zeller, Claude Kwe Yinda, Francisco Álvares, Sara Roque, Francisco Petrucci‐Fonseca, Raquel Godinho, Elisabeth Heylen, Marc Van Ranst, Jelle Matthijnssens,
Tópico(s): Animal Virus Infections Studies
2016 - Springer Science+Business Media | Archives of Virology
Danilo Alvares, Francisco J. Rubio,
Abstract We introduce a numerically tractable formulation of Bayesian joint models for longitudinal and survival data. The longitudinal process is modeled using generalized linear mixed models, while the survival process is modeled using a parametric general hazard structure. The two processes are linked by sharing fixed and random effects, separating the effects that play a role at the time scale from those that affect the hazard scale. This strategy allows for the inclusion of nonlinear and time‐ ...
Tópico(s): Statistical Distribution Estimation and Applications
2021 - Wiley | Statistics in Medicine
Gholam Hosein Yusefi, Raquel Godinho, Leili Khalatbari, Siamak Broomand, Hadi Fahimi, Fernando Martínez‐Freiría, Francisco Álvares,
... Fernando Martínez-Freiría (fmartinez-freiria@cibio.up.pt), Francisco Alvares (falvares@cibio.up.pt) Read the full textAboutPDF ...
Tópico(s): Genetic diversity and population structure
2021 - Wiley | Journal of Zoological Systematics & Evolutionary Research
Nádia Conceição‐Neto, Raquel Godinho, Francisco Álvares, Claude Kwe Yinda, Ward Deboutte, Mark Zeller, Lies Laenen, Elisabeth Heylen, Sara Roque, Francisco Petrucci‐Fonseca, Nuno Santos, Marc Van Ranst, João R. Mesquita, Jelle Matthijnssens,
Abstract Animal host–microbe interactions are a relevant concern for wildlife conservation, particularly regarding generalist pathogens, where domestic host species can play a role in the transmission of infectious agents, such as viruses, to wild animals. Knowledge on viral circulation in wild host species is still scarce and can be improved by the recent advent of modern molecular approaches. We aimed to characterize the fecal virome and identify viruses of potential conservation relevance of ...
Tópico(s): Bacteriophages and microbial interactions
2017 - Wiley | Ecology and Evolution
José Carlos Brito, André Luís Acosta, Francisco Álvares, Fabrice Cuzin,
In North Africa, and especially in the Sahara Desert, biodiversity is poorly known. Of the five widespread canid species present, one is Data Deficient, three are considered widespread although habitat selection could limit their area of occupancy, and distribution maps available are coarse for conservation planning. This study identifies biogeographic patterns in North-African canids through the combination of high resolution presence data with 16 environmental factors. Predictive models trained ...
Tópico(s): Zoonotic diseases and public health
2009 - Elsevier BV | Biological Conservation
... included in the investigation healded by the judge Francisco Alvares da Costa Pinto. Eleven slaves, one of whom ...
Tópico(s): Colonialism, slavery, and trade
1992 - Universidade de São Paulo. Instituto de Estudos Brasileiros | Revista do Instituto de Estudos Brasileiros
Francisco Álvares, José Domingues, Pablo Sierra, Pedro Primavera,
In the Iberian Peninsula, the coexistence between pastoral communities and wolves has given origin to a rich ethnographic heritage, expressed in myths and legends, practices related to medical uses of wolf parts, and constructions for hunting wolves. This article assesses such cultural dimension through interviews with inhabitants, field prospecting and a literature review. Our review indicates that cultural manifestations related to wolves are associated with two distinct perceptions of this carnivore: ...
Tópico(s): Human-Animal Interaction Studies
2011 - Taylor & Francis | Innovation The European Journal of Social Science Research
Raquel Godinho, Luís Llaneza, Juan Carlos Blanco, Susana Lopes, Francisco Álvares, Emilio José García, Vicente Palacios, Yolanda Cortés, Javier Talegón, Nuno Ferrand,
Abstract Hybridization between wild species and their domestic counterparts may represent a major threat to natural populations. However, high genetic similarity between the hybridizing taxa makes the detection of hybrids a difficult task and may hinder attempts to assess the impact of hybridization in conservation biology. In this work, we used a combination of 42 autosomal microsatellites together with Y‐chromosome microsatellite‐defined haplotypes and mtDNA sequences to investigate the occurrence ...
Tópico(s): Human-Animal Interaction Studies
2011 - Wiley | Molecular Ecology

Carla da Silva Carneiro, Eliane Teixeira Mársico, Roberta de Oliveira Resende Ribeiro, Carlos Adam Conte‐Júnior, Thiago Silveira Álvares, Edgar Francisco Oliveira de Jesus,
This work describes studies of the sodium tripolyphosphate (Na5P3O10) treatments on frozen shrimp muscle using Low Field Nuclear Magnetic Resonance (LF 1H NMR). Samples containing water only without any additives were used as controls. All experimental data were collected using thawed samples. A close correlation was established between the LF 1H NMR analysis and other physicochemical measurements (p < 0.01) used in this work including moisture, water-holding capacity, pH and color. Bi-exponential fitting ...
Tópico(s): Physiological and biochemical adaptations
2012 - Elsevier BV | LWT
Guillaume Chapron, Petra Kaczensky, John D. C. Linnell, Manuela von Arx, Đuro Huber, Henrik Andrén, José Vicente López‐Bao, Michal Adamec, Francisco Álvares, Ole Anders, Linas Balčiauskas, Vaidas Balys, Péter Bedő, Ferdinand Bego, Juan Carlos Blanco, Urs Breitenmoser, Henrik Brøseth, Luděk Bufka, Raimonda Bunikyte, Paolo Ciucci, Alexander Dutsov, Thomas Engleder, Christian Fuxjäger, Claudio Groff, Katja Holmala, Bledi Hoxha, Yorgos Iliopoulos, O. Ionescu, Jasna Jeremić, Klemen Jerina, Gesa Kluth, Felix Knauer, Ilpo Kojola, Ivan Kos, Miha Krofel, Jakub Kubala, Saša Kunovac, Josip Kusak, Miroslav Kutal, Olof Liberg, Aleksandra Majić Skrbinšek, Peep Männil, Ralph Manz, Éric Marboutin, Francesca Marucco, Dime Melovski, Kujtim Mersini, Yorgos Mertzanis, Robert W. Mysłajek, Sabina Nowak, John Oddén, Jānis Ozoliņš, Guillermo Palomero, Milan Paunović, Jens Persson, Hubert Potočnik, Pierre‐Yves Quenette, Georg Rauer, Ilka Reinhardt, Robin Rigg, Andreas Ryser, Valéria Salvatori, Tomaž Skrbinšek, Aleksandar Stojanov, Jon E. Swenson, László Szemethy, Aleksandër Trajçe, Elena Tsingarska-Sedefcheva, Martin Váňa, Rauno Veeroja, Petter Wabakken, Manfred Wölfl, Sybille Wölfl, Fridolin Zimmermann, Diana Zlatanova, Luigi Boitani,
The conservation of large carnivores is a formidable challenge for biodiversity conservation. Using a data set on the past and current status of brown bears ( Ursus arctos ), Eurasian lynx ( Lynx lynx ), gray wolves ( Canis lupus ), and wolverines ( Gulo gulo ) in European countries, we show that roughly one-third of mainland Europe hosts at least one large carnivore species, with stable or increasing abundance in most cases in 21st-century records. The reasons for this overall conservation success include protective ...
Tópico(s): Forest Management and Policy
2014 - American Association for the Advancement of Science | Science
João P. Maia, Francisco Álvares, Zbyszek Boratyński, José Carlos Brito, João V. Leite, D. James Harris,
Parasites play a major role in ecosystems, and understanding of host-parasite interactions is important for predicting parasite transmission dynamics and epidemiology. However, there is still a lack of knowledge about the distribution, diversity, and impact of parasites in wildlife, especially from remote areas. Hepatozoon is a genus of apicomplexan parasites that is transmitted by ingestion of infected arthropod vectors. However, alternative modes of transmission have been identified such as trophic ...
Tópico(s): Bird parasitology and diseases
2014 - Wildlife Disease Association | Journal of Wildlife Diseases

Carla da Silva Carneiro, Eliane Teixeira Mársico, Roberta de Oliveira Resende Ribeiro, Carlos Adam Conte‐Júnior, Thiago Silveira Álvares, Edgar Francisco Oliveira de Jesus,
Abstract The effects of polyphosphate on parameters of quality in shrimp (after thawing and cooking) were investigated using physicochemical analytical methods and l ow‐ f ield nuclear magnetic resonance ( LF 1 H NMR ) spectroscopy. The NMR data were treated by bi‐exponential fitting and compared with the physicochemical data. The physicochemical parameters demonstrated that treatments with different concentrations of sodium tripolyphosphate and different time exposures influenced parameters such as ...
Tópico(s): Aquaculture Nutrition and Growth
2013 - Wiley | Journal of Food Process Engineering
José Carlos Brito, Raquel Godinho, Fernando Martínez‐Freiría, Juan M. Pleguezuelos, Hugo Rebelo, Xavier Santos, Cândida Gomes Vale, Guillermo Velo‐Antón, Zbyszek Boratyński, Sílvia B. Carvalho, Sónia Ferreira, Duarte V. Gonçãlves, Teresa Luísa Silva, Pedro Tarroso, João C. Campos, João V. Leite, Joana Garrido Nogueira, Francisco Álvares, Neftalí Sillero, Andack Saad Sow, Soumía Fahd, Pierre‐André Crochet, Salvador Carranza,
ABSTRACT Deserts and arid regions are generally perceived as bare and rather homogeneous areas of low diversity. The S ahara is the largest warm desert in the world and together with the arid S ahel displays high topographical and climatic heterogeneity, and has experienced recent and strong climatic oscillations that have greatly shifted biodiversity distribution and community composition. The large size, remoteness and long‐term political instability of the S ahara‐ S ahel, have limited knowledge ...
Tópico(s): Animal Diversity and Health Studies
2013 - Wiley | Biological reviews/Biological reviews of the Cambridge Philosophical Society
João V. Leite, Francisco Álvares, Guillermo Velo‐Antón, José Carlos Brito, Raquel Godinho,
Tópico(s): Genetic and phenotypic traits in livestock
2015 - Springer Science+Business Media | Organisms Diversity & Evolution
José Vicente López‐Bao, Juan Carlos Blanco, Alejandro Rodrı́guez, Raquel Godinho, Víctor Sazatornil, Francisco Álvares, Emilio José García, Luís Llaneza, M. Rico, Yolanda Cortés, Vicente Palacios, Guillaume Chapron,
Granting legal protection to an endangered species has long been considered a major milestone for its conservation and recovery. A multitude of examples such as wolves in the contiguous USA (Boitani 2003) or many large carnivore populations in Europe (Chapron et al. 2014) have revealed how instrumental wildlife protection laws can be for species recovery. However, legal obligations to conserve endangered species may be useless if the rule of law is not properly enforced. Such situation is not exclusive ...
Tópico(s): Animal Behavior and Welfare Studies
2015 - Springer Science+Business Media | Biodiversity and Conservation
Klaus‐Peter Koepfli, John P. Pollinger, Raquel Godinho, Jacqueline A. Robinson, Amanda J. Lea, Sarah A. Hendricks, Rena M. Schweizer, Olaf Thalmann, Pedro Silva, Zhenxin Fan, Andrey A. Yurchenko, Pavel Dobrynin, Alex Makunin, James A. Cahill, Beth Shapiro, Francisco Álvares, José Carlos Brito, Eli Geffen, Jennifer A. Leonard, Kristofer M. Helgen, Warren E. Johnson, Stephen J. O’Brien, Blaire Van Valkenburgh, Robert K. Wayne,
The golden jackal of Africa (Canis aureus) has long been considered a conspecific of jackals distributed throughout Eurasia, with the nearest source populations in the Middle East. However, two recent reports found that mitochondrial haplotypes of some African golden jackals aligned more closely to gray wolves (Canis lupus) [1Rueness E.K. Asmyhr M.G. Sillero-Zubiri C. Macdonald D.W. Bekele A. Atickem A. Stenseth N.C. The cryptic African wolf: Canis aureus lupaster is not a golden jackal and is not ...
Tópico(s): Genetic diversity and population structure
2015 - Elsevier BV | Current Biology
Maris Hindrikson, Jaanus Remm, Małgorzata Pilot, Raquel Godinho, Astrid Vik Strønen, Laima Baltrūnaitė, Sylwia D. Czarnomska, Jennifer A. Leonard, Ettore Randi, Carsten Nowak, Mikael Åkesson, José Vicente López‐Bao, Francisco Álvares, Luís Llaneza, Jorge Echegaray, Carles Vilà, Jānis Ozoliņš, Dainis Ruņģis, Jouni Aspi, Ladislav Paule, Tomaž Skrbinšek, Urmas Saarma,
ABSTRACT The grey wolf ( C anis lupus ) is an iconic large carnivore that has increasingly been recognized as an apex predator with intrinsic value and a keystone species. However, wolves have also long represented a primary source of human–carnivore conflict, which has led to long‐term persecution of wolves, resulting in a significant decrease in their numbers, genetic diversity and gene flow between populations. For more effective protection and management of wolf populations in E urope, robust scientific ...
Tópico(s): Animal Behavior and Welfare Studies
2016 - Wiley | Biological reviews/Biological reviews of the Cambridge Philosophical Society
Víctor Sazatornil, Alejandro Rodrı́guez, Michael Klaczek, Mohsen Ahmadi, Francisco Álvares, Stephen M. Arthur, Juan Carlos Blanco, Bridget L. Borg, H. Dean Cluff, Yolanda Cortés, Emilio José García, Eli Geffen, Bilal Habib, Yorgos Iliopoulos, Mohammad Kaboli, Miha Krofel, Luís Llaneza, Francesca Marucco, John K. Oakleaf, David K. Person, Hubert Potočnik, Nina Ražen, Helena Rio‐Maior, Håkan Sand, David E. Unger, Petter Wabakken, José Vicente López‐Bao,
Large carnivores can be found in different scenarios of cohabitation with humans. Behavioral adaptations to minimize risk from humans are expected to be exacerbated where large carnivores are most vulnerable, such as at breeding sites. Using wolves as a model species, along with data from 26 study areas across the species' worldwide range, we performed a meta-analysis to assess the role of humans in breeding site selection by a large carnivore. Some of the patterns previously observed at the local ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2016 - Elsevier BV | Biological Conservation

Fábio de Sousa Menezes, Ângelo Saboia Borsatto, Nuno Álvares Pereira, Francisco José de Abreu Matos, Maria Auxiliadora Coelho Kaplan,
A mixture containing a new triterpene, chamaedrydiol (urs-12-ene-2α,3β-diol), and three known triterpenes (lup-20(29)-ene-2α,3β-diol, castanopsol and epigermanidiol) was isolated from Marsypianthes chamaedrys. The components in the mixture were identified using spectroscopic methods. In addition, a mixture of four less polar known triterpenes consisting of α-amyrin, β-amyrin, lupeol and germanicol, was also isolated.
Tópico(s): Traditional and Medicinal Uses of Annonaceae
1998 - Elsevier BV | Phytochemistry
Mónia Nakamura, Raquel Godinho, Helena Rio‐Maior, Sara Roque, Antigoni Kaliontzopoulou, J. Bernardo, Diana Castro, Susana Lopes, Francisco Petrucci‐Fonseca, Francisco Álvares,
Tópico(s): Species Distribution and Climate Change
2017 - Springer Science+Business Media | European Journal of Wildlife Research
Pedro Silva, José Vicente López‐Bao, Luís Llaneza, Francisco Álvares, Susana Lopes, Juan Carlos Blanco, Yolanda Cortés, Emilio José García, Vicente Palacios, Helena Rio‐Maior, Nuno Ferrand, Raquel Godinho,
Abstract Highly mobile mammalian carnivores are expected to have the capability to maintain high levels of gene flow across large geographic scales. Nonetheless, surprising levels of genetic structure have been found in many such populations. We combined genetic and spatial behavioural information from wolves ( Canis lupus ) in the Iberian Peninsula (Western Europe) during the last two decades to present a particular case of low dispersal levels in a large carnivore population persisting in human-dominated ...
Tópico(s): Genetic and phenotypic traits in livestock
2018 - Nature Portfolio | Scientific Reports
Helena Rio‐Maior, Pedro Beja, Mónia Nakamura, Francisco Álvares,
Tópico(s): Animal Behavior and Welfare Studies
2018 - Springer Science+Business Media | Mammalian Biology
Joana Bencatel, Catarina Ferreira, A. Márcia Barbosa, Luís Miguel Rosalino, Francisco Álvares,
Information regarding species' status at a regional scale is instrumental for effective conservation planning. Some regions of southwestern Europe, such as Portugal, albeit included in the Mediterranean biodiversity hotspot, lack a detailed assessment of the distribution patterns of several taxonomic groups, such as carnivores. Moreover, information is scattered, often unreliable and biased towards some species or regions. This study aimed at reviewing the existing knowledge on mammalian terrestrial ...
Tópico(s): Ecology and biodiversity studies
2018 - Public Library of Science | PLoS ONE

Michael Ruberson Ribeiro da Silva, Leonardo Maurício Diniz, Jéssica Barreto Ribeiro dos Santos, Edna Afonso Reis, Adriana Rodrigues da Mata, Vânia Eloísa de Araújo, Juliana Álvares-Teodoro, Francisco de Assis Acúrcio,
The objective of this study was to evaluate the use of drugs and the factors associated with polypharmacy in patients with diabetes mellitus (DM) in Minas Gerais. Descriptive analysis of drugs in use and logistic regression to estimate the association between socio-demographic and clinical characteristics with polypharmacy were performed. Of the 2619 respondents, 56.5% were in polypharmacy. Drugs for DM, agent in renin-angiotensin system, and diuretics are the most frequently used. Factors such as ...
Tópico(s): Public Health in Brazil
2018 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva

Michael Ruberson Ribeiro da Silva, Jéssica Barreto Ribeiro dos Santos, Alessandra Maciel Almeida, Alexander Itria, Adriana María Kakehasi, Juliana Álvares-Teodoro, Francisco de Assis Acúrcio,
To evaluate the persistence of biological (TNF inhibitor [anti-TNF]) and synthetic (conventional synthetic disease-modifying antirheumatic drugs [csDMARDs]) antirheumatic agents for psoriatic arthritis and their associated factors.A historical cohort was developed. Persistence and associated factors were evaluated at 6 and 12 months.A total of 161 patients were included. The anti-TNF treatment presented higher persistence as compared with csDMARDs at 6 (83.4 vs 50.8%; p < 0.05) and 12 months (66.4 vs 35. ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2019 - Future Science Ltd | Future Science OA

Michael Ruberson Ribeiro da Silva, Jéssica Barreto Ribeiro dos Santos, Alessandra Maciel Almeida, Augusto Afonso Guerra, Juliana Álvares-Teodoro, Francisco de Assis Acúrcio,
Background: Biological therapies have a significant economic and clinical burden but, in general, lose their effectiveness over time. This study evaluated the medication persistence and costs associated to use of anti-TNF agents for psoriatic arthritis (PsA) treatment. Methods: A historical cohort composed of individuals in Brazil with PsA diagnosis was developed during the period between 2010 and 2015. The difference among the anti-TNF agents was verified by the log-rank test. The predictors of ...
Tópico(s): Psoriasis: Treatment and Pathogenesis
2019 - Taylor & Francis | Expert Review of Clinical Immunology
Helena Rio‐Maior, Mónia Nakamura, Francisco Álvares, Pedro Beja,
Large carnivores often inhabit human-dominated landscapes, where avoidance of anthropogenic risks can constrain their use of space and time. Large carnivore conservation thus requires designing landscapes of coexistence, which should provide suitable habitats and dispersal opportunities in areas shared with humans. This study investigates the landscape of coexistence for the Iberian wolf, using movement data from 15 individuals to model how human-related risks constrain the spatial distribution ...
Tópico(s): Species Distribution and Climate Change
2019 - Elsevier BV | Biological Conservation
Valéria Salvatori, Valerio Donfrancesco, Arie Trouwborst, Luigi Boitani, John D. C. Linnell, Francisco Álvares, Mikael Åkesson, Vaidas Balys, Juan Carlos Blanco, Silviu Chiriac, Duško Ćirović, Claudio Groff, Murielle Guinot-Ghestem, Đuro Huber, Ilpo Kojola, Josip Kusak, Miroslav Kutal, Yorgos Iliopulos, O. Ionescu, Aleksandra Majić Skrbinšek, Peep Männil, Francesca Marucco, Dime Melovski, Robert W. Mysłajek, Sabina Nowak, Jānis Ozoliņš, Georg Rauer, Ilka Reinhardt, Robin Rigg, Laurent Schley, Tomaž Skrbinšek, Linn Svensson, Aleksandër Trajçe, Igor Trbojević, Elena Tzingarska, Manuela von Arx, Paolo Ciucci,
Tópico(s): Human-Animal Interaction Studies
2020 - Elsevier BV | Biological Conservation