Daniel A. Marinho, Víctor Machado Reis, Francisco Alves, João Paulo Vilas‐Boas, Leandro Machado, António Silva, Abel Rouboa,
This study used a computational fluid dynamics methodology to analyze the effect of body position on the drag coefficient during submerged gliding in swimming. The k-epsilon turbulent model implemented in the commercial code Fluent and applied to the flow around a three-dimensional model of a male adult swimmer was used. Two common gliding positions were investigated: a ventral position with the arms extended at the front, and a ventral position with the arms placed along side the trunk. The simulations ...
Tópico(s): Cardiovascular and Diving-Related Complications
2009 - International Society of Biomechanics | Journal of Applied Biomechanics
Elenilde Gomes-Santos, Roberto Salvatori, Thiago O. Ferrão, Carla R. P. Oliveira, Rachel D C Araújo Diniz, João A. M. Santana, Francisco A. Pereira, Rita A. A. Barbosa, Anita H. O. Souza, Enaldo Vieira de Melo, Carlos C. Epitácio-Pereira, Alécia A. Oliveira‐Santos, Ingrid A. S. Oliveira, Julianne Alves Machado, Francisco J. Santana-Júnior, José Augusto Soares Barreto-Filho, Manuel H. Aguiar‐Oliveira,
Adult-onset GH deficiency (GHD) increases visceral adiposity and the activity of the enzyme 11β-hydroxysteroid dehydrogenase, which converts cortisone (E) to cortisol (F), both linked to insulin resistance and increased cardiovascular risk. Conversely, we reported that adults with congenital isolated GHD (IGHD) have increased insulin sensitivity.To assess the type of fat distribution and the amount of visceral and sc fat and to correlate them to the F/E ratio in adults with untreated IGHD due to a mutation ...
Tópico(s): Birth, Development, and Health
2014 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Produção Nacional
Revisado por pares
Antônia Jaqueline Nobre Bezerra, Francisca Crislândia Oliveira Silva, Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuelle Machado Marinho, Márcia Machado Marinho, Francisco Ernani Alves Magalhães, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Croton zehntneri is a plant known as canelinha de cunhã, prevalent in the northeast region of Brazil. Many constituents of the vegetable have already been studied, and their pharmacological properties have been proven, but this is the first study to analyze the antinociceptive effect in adult zebrafish (ZFa) of the triterpene acetyl aleuritolic acid (AAA) isolated from the stem bark. The animals (ZFa; n = 6/group) were treated intraperitoneally (ip; 20 μL) with AAA (0.1 or 0.3 or 1.0 mg/mL) or vehicle ( ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Biochemical and Biophysical Research Communications
Daniel A. Marinho, António Silva, Víctor Machado Reis, Tiago M. Barbosa, João Paulo Vilas‐Boas, Francisco Alves, Leandro Machado, Abel Rouboa,
The purpose of this study was to analyze the hydrodynamic characteristics of a realistic model of an elite swimmer hand/forearm using three-dimensional computational fluid dynamics techniques. A three-dimensional domain was designed to simulate the fluid flow around a swimmer hand and forearm model in different orientations (0°, 45°, and 90° for the three axes Ox, Oy and Oz). The hand/forearm model was obtained through computerized tomography scans. Steady-state analyses were performed using the ...
Tópico(s): Cardiovascular Effects of Exercise
2011 - International Society of Biomechanics | Journal of Applied Biomechanics
Produção Nacional
Revisado por pares
Hélder Miguel Fernandes, Víctor Machado Reis, José Vilaça‐Alves, Francisco Saavedra, Felipe J. Aidar, Robert J. Brustad,
Epidemiologically-based evidence has demonstrated that a substantial number of athletes and exercisers are injured each year, which can result in physical disability as well as other negative physical, social and psychological consequences. Accumulated research has indicated that the prevalence of sport and physical activity-related injuries varies based on gender, age group, type of sport, level of participation, and role on the team, among other considerations. Although physical causes are the ...
Tópico(s): Sport Psychology and Performance
2014 - Autonomous University of Barcelona | Revista de psicología del deporte
Produção Nacional
Renata Passos Machado Vieira, Francisco Régis Vieira Alves, Paula Catarino,
Estudos relacionados à sequências lineares e recorrentes tem proporcionado a abordagem de outras bem menos conhecidas do que a Sequência de Fibonacci. Nesse sentido, este trabalho aborda uma breve introdução sobre a Sequência de Leonardo, assim como uma discussão à respeito das relações recorrentes bidimensionais desses números a partir do seu modelo unidimensional. Algumas propriedades e identidades são ainda introduzidas, de forma a estabelecer a relação existente entre essas duas sequências de ...
Tópico(s): Advanced Mathematical Theories and Applications
2019 - | Revista Sergipana de Matemática e Educação Matemática
Produção Nacional
Revisado por pares
Milena Carolina dos Santos Mangueira, Renata Passos Machado Vieira, Francisco Régis Vieira Alves, Paula Catarino,
Abstract In this article, we will define Padovan’s hybrid numbers, based on the new noncommutative numbering system studied by Özdemir ([7]). Such a system that is a set involving complex, hyperbolic and dual numbers. In addition, Padovan’s hybrid numbers are created by combining this set, satisfying the relation ih = −hi = ɛ + i . Given this, some properties and identities are shown for these numbers, such as Binet’s formula, generating matrix, characteristic equation, norm, and generating function. In addition, ...
Tópico(s): Mathematics and Applications
2020 - De Gruyter Open | Annales Mathematicae Silesianae
Daniel A. Marinho, Tiago M. Barbosa, Víctor Machado Reis, P.L. Kjendlie, Francisco Alves, João Paulo Vilas‐Boas, Leandro Machado, António Silva, Abel Rouboa,
The main aim of this study was to investigate the effect of finger spread on the propulsive force production in swimming using computational fluid dynamics. Computer tomography scans of an Olympic swimmer hand were conducted. This procedure involved three models of the hand with differing finger spreads: fingers closed together (no spread), fingers with a small (0.32 cm) spread, and fingers with large (0.64 cm) spread. Steady-state computational fluid dynamics analyses were performed using the Fluent ...
Tópico(s): Sports Performance and Training
2010 - International Society of Biomechanics | Journal of Applied Biomechanics
Produção Nacional
Revisado por pares
Joyce dos Reis Lima, Maria Kueirislene Amâncio Ferreira, Ketelly Vanessa Barros Sales, Antônio Wlisses da Silva, Emanuelle Machado Marinho, Francisco Ernani Alves Magalhães, Emmanuel Silva Marinho, Márcia Machado Marinho, Matheus Nunes da Rocha, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Croton blanchetianus is known as 'marmeleiro preto', a very widespread shrub in Northeast Brazil. Terpenoids, steroids and phenolic compounds are among the reported secondary metabolites of the Croton genus that are a potential source of bioactive compounds. This study evaluated the anxiolytic potential of clerodine-type diterpene, sonderianin (CBWS) isolated from the stem bark of C. blanchetianus and its mechanism of action in adult zebrafish (Danio rerio) (ZFa). The anticonvulsant and anti-acetylcholinesterase ...
Tópico(s): Computational Drug Discovery Methods
2021 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Maria Altenfelder Santos, Mark Drew Crosland Guimarães, Ernani Tiarajú de Santa Helena, Cáritas Relva Basso, Felipe Campos Vale, Wania Maria do Espírito Santo Carvalho, Ana Maroso Alves, Gustavo Machado Rocha, Francisco de Assis Acúrcio, Maria das Graças Braga Ceccato, Rogério Ruscitto do Prado, Paulo Rossi Menezes, Maria Inês Battistella Nemes,
Patient adherence to antiretroviral therapy (ART) is critical for HIV treatment success. Monitoring rates of adherence in public HIV outpatient care facilities can improve outcomes in Brazil where ART is universally available.We conducted a national cross-sectional survey of ART adherence in 2010. Participants were selected using a multistage probability sample. First, HIV outpatient care facilities were stratified according to 7 Organizational Quality Classification (OQC) groups and regions. Second, ...
Tópico(s): Adolescent Sexual and Reproductive Health
2018 - Wolters Kluwer | Medicine
Produção Nacional
Revisado por pares
Christiano de Sousa Machado de Matos, Ellen Noly Barrocas, José da Cruz Machado, Francisco Cardoso Alves,
At post-harvest period, quality of corn seeds may be influenced by several important factors such as: presence of harmful microorganisms, chemical treatments, host species genotype and storage conditions. The objective of this study was to evaluate the performance of corn seeds, hybrids 2B 688 and 2B 710, with high incidence of fungus Fusarium verticillioides and treated with mixtures of fungicides thiophanate-methyl + pyraclostrobin (50 mL a.i .100 kg-1 of seeds) and carbendazim + thiram + micronutrients ( ...
Tópico(s): Plant tissue culture and regeneration
2013 - Associação Brasileira de Tecnologia de Sementes | Journal of Seed Science
Produção Nacional
Revisado por pares
Sylvio Botelho-Júnior, Olga Lima Tavares Machado, Kátia Valevski Sales Fernandes, Francisco José Alves Lemos, Viviane Abrantes Perdizio, Antônia Elenir Amâncio Oliveira, Leandro R. Monteiro, Mauri Lima Filho, Tânia Jacinto,
Tópico(s): Insect-Plant Interactions and Control
2014 - Springer Science+Business Media | Planta
Produção Nacional
Revisado por pares
Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Atilano Lucas dos Santos Moura, Ketelly Vanessa Barros Sales, Emanuelle Machado Marinho, Joyce do Nascimento Martins Cardoso, Márcia Machado Marinho, Paulo Nogueira Bandeira, Francisco Ernani Alves Magalhães, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
In the treatment of anxiety and seizures, drugs of the benzodiazepine (BZD) class are used, which act on the Central Nervous System (CNS) through the neurotransmitter gamma-aminobutyric acid (GABA). Flavonoids modulate GABAA receptors. The aim of this study was to evaluate the anxiolytic and anticonvulsant effects of synthetic chalcones and their mechanisms of action via the GABAergic system, using adult zebrafish (ZFa). The animals were treated with chalcones (4.0 or 20 or 40 mg/kg; 20 µL; i.p) and ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2021 - Elsevier BV | Epilepsy & Behavior
Renata Passos Machado Vieira, Francisco Régis Vieira Alves, Paula Catarino,
In the present text, we present some possibilities to formalize the mathematical content and a historical context, referring to a numerical sequence of linear and recurrent form, known as Sequence of Padovan or Cordonnier. Throughout the text some definitions are discussed, the matrix approach and the relation of this sequence with the plastic number. The explicit exploration of the possible paths used to formalize the explored mathematical subject, comes with an epistemological character, still ...
Tópico(s): Mathematics and Applications
2020 - | International Journal of Trends in Mathematics Education Research
Produção Nacional
Milena Carolina dos Santos Mangueira, Renata Passos Machado Vieira, Francisco Régis Vieira Alves, Paula Catarino,
This article deals with the generalization of the matrix form of the Oresme sequence, extending it to the field of integers. In addition, the two valid generating matrices were discussed, through the permutation of the rows and columns, respectively, totaling two valid matrices of Oresme for the left-hand side, and two more generating matrices of Oresme for the right-hand side. In addition, a new Oresme sequence was introduced, given through the hybridization process of these numbers, obtaining ...
Tópico(s): Advanced Mathematical Theories
2021 - | Notes on Number Theory and Discrete Mathematics
Produção Nacional
Revisado por pares
Antônio Francisco Alves da Silva, Filipe Brum Machado, Érika Cristina Pavarino, Joice Matos Biselli, Bruna Lancia Zampieri, Ronaldo da Silva Francisco, Pedro Thyago Mozer Rodrigues, Douglas Terra Machado, Cíntia Barros Santos-Rebouças, Maria Gomes Fernandes, Susana Marina Chuva de Sousa Lopes, Álvaro Fabrício Lopes Rios, Enrique Medina‐Acosta,
The supernumerary chromosome 21 in Down syndrome differentially affects the methylation statuses at CpG dinucleotide sites and creates genome-wide transcriptional dysregulation of parental alleles, ultimately causing diverse pathologies. At present, it is unknown whether those effects are dependent or independent of the parental origin of the nondisjoined chromosome 21. Linkage analysis is a standard method for the determination of the parental origin of this aneuploidy, although it is inadequate ...
Tópico(s): Prenatal Screening and Diagnostics
2016 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Flávio Ribeiro Alves, Francisco B. Costa, Pedro Machado, Anaemília das Neves Diniz, Adriana V.C. Araújo, Carlos Eduardo Ambrósio, Porfírio C. Guerra,
The capuchin monkey is widespread both north and south of the Legal Amazon and in the Brazilian cerrado. Ten clinically healthy capuchin monkeys were submitted to an anatomical and radiographic study of their thoracic cavities. The radiographic evaluation allowed the description of biometric values associated with the cardiac silhouette and thoracic structures. Application of the VHS (vertebral heart size) method showed positive correlation (P<0.05) with depth of the thoracic cavity, as well as ...
Tópico(s): Coronary Artery Anomalies
2012 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira
Produção Nacional
Revisado por pares
Fabiana Rezende Muniz, Amancio de Souza, Liliane Cristina Libório Stipp, Evandro Henrique Schinor, Waldyr L. de Freitas, Ricardo Harakava, Dagmar Ruth Stach‐Machado, Jorge Alberto Marques Rezende, Francisco de Assis Alves Mourão Filho, B. M. J. Mendes,
Transgenic Citrus sinensis (L.) Osb. plants, cvs. Valencia and Hamlin, expressing Citrus tristeza virus (CTV) derived sequences were obtained by genetic transformation. The gene constructs were pCTV-CP containing the 25 kDa major capsid protein gene (CTV-CP), pCTV-dsCP containing the same CTV-CP gene in an intron-spliced hairpin construct, and pCTV-CS containing a 559 nt conserved region of the CTV genome. The transgenic lines were identified by PCR and the transgene integration was confirmed by Southern ...
Tópico(s): Plant tissue culture and regeneration
2012 - Institute of Experimental Botany of the Czech Academy of Sciences | Biologia Plantarum
Produção Nacional
Revisado por pares
Francisco Acácio Alves, Marcelo Pelajo‐Machado, Paulo Renato Rivas Totino, Mariana Tavares de Souza, Evonnildo Costa Gonçalves, Maria Paula Cruz Schneider, J. Muniz, Marco Aurélio Krieger, Marcia CR Andrade, Cláudio Tadeu Daniel‐Ribeiro, Leonardo J. M. Carvalho,
The understanding of the mechanisms of immunity in malaria is crucial for the rational development of interventions such as vaccines. During blood stage infection, the spleen is considered to play critical roles in both immunity and immunopathology of Plasmodium falciparum infections.Saimiri sciureus monkeys were inoculated with blood stages of P. falciparum (FUP strain) and spleens removed during acute disease (days 7 and 13 of infection) and during convalescence (15 days after start of chloroquine ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2015 - BioMed Central | Malaria Journal
Produção Nacional
Milena Carolina dos Santos Mangueira, Renata Passos Machado Vieira, Francisco Régis Vieira Alves, Paula Catarino,
Given the purpose of mathematical evolution of Leonardo's sequence, we have the prospect of introducing complex polynomials, bivariate polynomials and bivariate polynomials around these numbers. Thus, this article portrays in detail the insertion of the variable x, y and the imaginary unit i in the sequence of Leonardo. Nevertheless, the mathematical results from this process of complexification of these numbers are studied, correlating the mathematical evolution of that sequence.
Tópico(s): Architecture and Art History Studies
2022 - | Notes on Number Theory and Discrete Mathematics
Produção Nacional
Revisado por pares
Giovanni Francisco Rabelo, Adilson Machado Enes, Roberto Alves Braga, Inácio Maria Dal Fabbro,
Tópico(s): Bee Products Chemical Analysis
2011 - Elsevier BV | Biosystems Engineering
António Silva, Daniel A. Marinho, Víctor Machado Reis, Francisco Alves, João Paulo Vilas‐Boas, Leandro Machado, Abel Rouboa,
Computational Fluid Dynamics (CFD) has been used in biomechanics studies applied to medicine and sport. Concerning sports, the main results suggested that a three dimensional CFD analysis of a human form could provide useful information about swimming. PURPOSE: To analyze the propulsive force in a swimmer hand/forearm 3-D segment using CFD. METHODS: A 3-D domain was created to simulate the fluid flow around a model of a swimmer hand and forearm. Models were created by computerized tomography scans ...
Tópico(s): Sports Dynamics and Biomechanics
2008 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Produção Nacional
Revisado por pares
Paulo S. G. de Mattos Neto, Manoel H. N. Marinho, Hugo Valadares Siqueira, Yara de Souza Tadano, Vivian Machado, Thiago Antonini Alves, João Fausto Lorenzato de Oliveira, Francisco Madeiro,
Particulate matter (PM) is one of the most harmful air pollutants to human health studied worldwide. In this scenario, it is of paramount importance to monitor and predict PM concentration. Artificial neural networks (ANN) are commonly used to forecast air pollution levels due to their accuracy. The use of partition on prediction problems is well known because decomposition of time series allows the latent components of the original series to be revealed. It is a matter of extracting the “deterministic” ...
Tópico(s): Energy Load and Power Forecasting
2020 - Multidisciplinary Digital Publishing Institute | Sustainability
Produção Nacional
Revisado por pares
Carolina Bueno, Felipe Lopes Alves, Lara M. Pinheiro, Laura Pérez, Vanessa Ochi Agostini, Elisa Helena Leão Fernandes, Osmar O. Möller, Jair Weschenfelder, Grasiela Lopes Leães Pinho, Mônica Wallner-Kersanach, Renata Rodrigues de Moura, Jimena Durán, Ismael Etchevers, Luíza Dy Fonseca Costa, Chariane Camila Werlang, Eduardo Calixto Bortolin, Eunice da Costa Machado, Rubens César Lopes Figueira, Paulo Alves de Lima Ferreira, Carlos Francisco Ferreira de Andrade, L. Fornaro, Felipe García‐Rodríguez,
The palaeolimnological conditions of Mirim Lagoon, a large coastal shallow lagoon under the influence of historical human impacts related to the development of the primary sector of the economy were reconstructed. The first significant human impact consisted of locking the estuarine system to induce the transition from brackish to freshwater conditions. During this transition, the sedimentation rate consistently increased from pre-disturbance values of 0.25 cm yr-1 to >1 cm yr-1. A concomitant increase ...
Tópico(s): Maritime and Coastal Archaeology
2021 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Valdemar Francisco da Silva Filho, José Luiz Francisco Alves, Gabriel Francisco Reus, Ricardo Antônio Francisco Machado, Cintia Marangoni, Ariovaldo Bolzan,
This study evaluated a new process for separation of aromatic compounds based on falling film distillation at thermosyphon-assisted atmospheric pressure (Destubcal Technology), in order to obtain enriched mass fractions of toluene in the distillate stream. Two compact experimental units were used: single-tube and multi-tubes on a pilot scale. The experimental tests were divided into two groups: isothermal and non-isothermal condition. The optimal feed mass flow rate, evaporator temperature and feed ...
Tópico(s): Advanced Control Systems Optimization
2018 - Elsevier BV | Chemical Engineering and Processing - Process Intensification
Produção Nacional
Francisco Régis Vieira Alves, Renata Passos Machado Vieira,
The work deals with the study of the roots of the characteristic polynomial derived from the Leonardo sequence, using the Newton fractal to perform a root search. Thus, Google Colab is used as a computational tool to facilitate this process. Initially, we conducted a study of the Leonardo sequence, addressing it fundamental recurrence, characteristic polynomial, and its relationship to the Fibonacci sequence. Following this study, the concept of fractal and Newton's method is approached, so that ...
Tópico(s): Advanced Mathematical Theories and Applications
2019 - | International Electronic Journal of Mathematics Education
André De Sousa Machado, Francisco Alves de Sousa, Joana Costa, Ana Silva, Ana Teresa Pinto, Daniel Simmen, Hans Rudolf Briner, Luís Meireles,
Introduction Olfactory dysfunction (OD) is often a devaluated sensorial affection. The objective evaluation of this dysfunction doesn’t evaluate its compromise in patients’ daily life. Therefore, the use of a Portuguese-validated tool is of uttermost importance to objectively scale the pathology presented by these patients. Objective We aim to validate and cross-culturally adapt the Olfactory Disorders Questionnaire (ODQ) in the Portuguese language. Methods A prospective study was carried out to evaluate ...
Tópico(s): Color perception and design
2022 - Cureus, Inc. | Cureus
Produção Nacional
Revisado por pares
Filipe Brum Machado, Fabricio Brum Machado, Milena Amendro Faria, Viviane Lamim Lovatel, Antônio Francisco Alves da Silva, Claudia Pamela Radic, Carlos Daniel De Brasi, Álvaro Fabrício Lopes Rios, Susana Marina Chuva de Sousa Lopes, Leonardo Serafim da Silveira, Carlos R. Ruiz‐Miranda, Ester Silveira Ramos, Enrique Medina‐Acosta,
X-chromosome inactivation (XCI) is the epigenetic transcriptional silencing of an X-chromosome during the early stages of embryonic development in female eutherian mammals. XCI assures monoallelic expression in each cell and compensation for dosage-sensitive X-linked genes between females (XX) and males (XY). DNA methylation at the carbon-5 position of the cytosine pyrimidine ring in the context of a CpG dinucleotide sequence (5meCpG) in promoter regions is a key epigenetic marker for transcriptional ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Filipe Brum Machado, Antônio Francisco Alves da Silva, Liliana Carmen Rossetti, Carlos Daniel De Brasi, Enrique Medina‐Acosta,
HaemophiliaVolume 17, Issue 2 p. 257-266 Informativeness of a novel multiallelic marker-set comprising an F8 intron 21 and three tightly linked loci for haemophilia A carriership analysis F. B. MACHADO, F. B. MACHADO Núcleo de Diagnóstico e Investigação Molecular, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ, Brazil Hospital Escola Álvaro Alvim, Campos dos Goytacazes, RJ, Brazil Present address: Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2010 - Wiley | Haemophilia
Produção Nacional
Revisado por pares
José Luiz Francisco Alves, Jean Constantino Gomes da Silva, Guilherme Davi Mumbach, Ricardo Francisco Alves, Rênnio Félix de Sena, Ricardo Antônio Francisco Machado, Cintia Marangoni,
This work provides the first insights on the bioenergy potential of macauba endocarp (Acrocomia aculeate) based on the pyrolysis kinetics and thermodynamic parameters of activation. The kinetic triplet was obtained from non-isothermal thermogravimetric data by using four isoconversional methods, kinetic compensation effect, and master-plots method. The pyrolysis behavior of macauba endocarp was modeled with three independent parallel reactions, describing the devolatilization of pseudo-hemicellulose, ...
Tópico(s): Biodiesel Production and Applications
2021 - Elsevier BV | Thermochimica Acta