Produção Nacional
Revisado por pares
Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos, Maria Kueirislene Amâncio Ferreira, Francisco Ernani Alves Magalhães, D.S. da Silva, Paulo Nogueira Bandeira, Gilberto D. Saraiva, Otília Deusdênia Loiola Pessoa, Nágila Maria Pontes Silva Ricardo, Beatriz Gonçalves Cruz, Alexandre Magno Rodrigues Teixeira,
The use of films or membranes to treat cutaneous lesions has become a standard therapeutic procedure in the last two decades. For this reason, many polymeric materials such as chitosan, collagen, alginate, and gelatin, have been investigated to better understand their physical, chemical and biological properties. This study addresses the preparation, structural and spectroscopic characterization of chitosan membranes, chitosan with glycerol and chitosan with glycerol plus allantoin as the active ...
Tópico(s): Silk-based biomaterials and applications
2019 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Leonardo Santos Amâncio Cabral, Francisco Ricardo Lins Vieira de Melo,
RESUMO O presente artigo tem como escopo principal apresentar, com base em dados de escala nacional, uma análise crítica acerca da normatização e legitimação do acesso e da participação do público-alvo da Educação Especial em instituições de ensino superior. Considerando-se que as normativas vigentes - ao se depararem com a pluralidade política, histórica, econômica, social e cultural - incidem, à sua maneira, sobre cada contexto. Assim se optou por realizar um estudo exploratório no âmbito das cinco ...
Tópico(s): Social and Political Issues
2017 - UNIVERSIDADE FEDERAL DO PARANÁ | Educar em Revista
Produção Nacional
Revisado por pares
Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuela L. Rebouças, Francisco Rogênio da Silva Mendes, Atilano Lucas dos Santos Moura, Jane Eire Silva Alencar de Menezes, Márcia Machado Marinho, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
Benzodiazepines are highly effective in combating anxiety; however, they have considerable adverse effects, so it is important to discover new safe anxiolytic agents. This study was designed to investigate the effect of the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone (HTMCX) on anxiety and seizure behavior in adult zebrafish and its possible mechanisms of action. The acute toxicity of 96 h of HTMCX was analyzed, and the open and light/dark field tests (n = 6 animals/group) were used to assess ...
Tópico(s): Neuroscience and Neuropharmacology Research
2021 - Springer Science+Business Media | Naunyn-Schmiedeberg s Archives of Pharmacology
Produção Nacional
Revisado por pares
Francisco Wagner Queiroz Almeida-Neto, Leonardo P. da Silva, Maria Kueirislene Amâncio Ferreira, Francisco Rogênio da Silva Mendes, Kevin K.A. de Castro, Paulo Nogueira Bandeira, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos, Norberto de Kássio Vieira Monteiro, Emmanuel Silva Marinho, Pedro de Lima‐Neto,
The molecule N-{4'-[(E)-3-(Fluorophenyl)-1-(phenyl)-prop-2-en-1-one]} chalcone (PAAPFBA) was recently synthesized due to the growing interest in the chemistry of the chalcone. The quantum chemical calculations were carried out to make a complete theoretical characterization (structural, spectroscopy, nonlinear optical, and electronic properties) employing three Density Functional Theory (DFT) methods like B3LYP, mPW1PW91, and M06–2X at 6–311++G(d,p) basis set. After all these characterizations, the ...
Tópico(s): Photochemistry and Electron Transfer Studies
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Matheus da Silva Campelo, João Francisco Câmara Neto, Álvaro Henrique Candido de Souza, Maria Kueirislene Amâncio Ferreira, Hélcio Silva dos Santos, Nilce V. Gramosa, Sandra de Aguiar Soares, Nágila Maria Pontes Silva Ricardo, Jane Eire Silva Alencar de Menezes, Maria Elenir Nobre Pinho Ribeiro,
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2023 - Springer Nature | DARU Journal of Pharmaceutical Sciences
Produção Nacional
Revisado por pares
Jayze da Cunha Xavier, Francisco Wagner Queiroz Almeida-Neto, Priscila Teixeira da Silva, Emmanuel Silva Marinho, Maria Kueirislene Amâncio Ferreira, Francisco Ernani Alves Magalhães, C.E.S. Nogueira, Paulo Nogueira Bandeira, Jane Eire Silva Alencar de Menezes, Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos,
Zebrafish is a model animal that is used for neurobehavioral studies. It is an excellent model organism for pharmacological studies and/or safety research at an early stage of drug development. In this work, the chalcone (2E, 4E)-1-(2‑hydroxy-3,4,6-trimethoxyphenyl)-5-phenylpenta-2,4‑dien‑1-one, was synthesized by the Claisen-Schmidt condensation from two natural products: 2‑hydroxy-3,4,6-trimethoxyacetophenone and cinnamaldehyde. The molecular structure of this compound was confirmed by spectroscopic ...
Tópico(s): Nonlinear Optical Materials Research
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Atilano Lucas dos Santos Moura, Ketelly Vanessa Barros Sales, Emanuelle Machado Marinho, Joyce do Nascimento Martins Cardoso, Márcia Machado Marinho, Paulo Nogueira Bandeira, Francisco Ernani Alves Magalhães, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
In the treatment of anxiety and seizures, drugs of the benzodiazepine (BZD) class are used, which act on the Central Nervous System (CNS) through the neurotransmitter gamma-aminobutyric acid (GABA). Flavonoids modulate GABAA receptors. The aim of this study was to evaluate the anxiolytic and anticonvulsant effects of synthetic chalcones and their mechanisms of action via the GABAergic system, using adult zebrafish (ZFa). The animals were treated with chalcones (4.0 or 20 or 40 mg/kg; 20 µL; i.p) and ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2021 - Elsevier BV | Epilepsy & Behavior
Produção Nacional
Revisado por pares
Antônia Jaqueline Nobre Bezerra, Francisca Crislândia Oliveira Silva, Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuelle Machado Marinho, Márcia Machado Marinho, Francisco Ernani Alves Magalhães, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Croton zehntneri is a plant known as canelinha de cunhã, prevalent in the northeast region of Brazil. Many constituents of the vegetable have already been studied, and their pharmacological properties have been proven, but this is the first study to analyze the antinociceptive effect in adult zebrafish (ZFa) of the triterpene acetyl aleuritolic acid (AAA) isolated from the stem bark. The animals (ZFa; n = 6/group) were treated intraperitoneally (ip; 20 μL) with AAA (0.1 or 0.3 or 1.0 mg/mL) or vehicle ( ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Biochemical and Biophysical Research Communications
Antônio Carlos Rodrigues Guimarães, Caroline Dias Amancio de Lima, Francisco Thiago Sacramento Aragão, Laura Maria Goretti da Motta, Juliana Tanabe Assad dos Santos,
Laterite gravels have been successfully adopted as pavement materials in the field. Despite that, they are often rejected in material selection processes because of its base on traditional gradation and consistency limits requirements. To allow a deeper evaluation of such material found abundantly in tropical countries, along to characterizing traditional parameters, repeated load triaxial tests were performed in a Laterite Gravel from Acre/Brazil to evaluate its elastic and plastic behavior through ...
Tópico(s): Geotechnical Engineering and Soil Mechanics
2023 - | Soils and Rocks
Produção Nacional
Revisado por pares
Francisco Lucas Alves Batista, Luiza Michelly Gonçalves Lima, Izamar A. Abrante, José Ismael Feitosa de Araújo, Francisca Leidivânia Alves Batista, Izabel A. Abrante, Erlândia A. Magalhães, Daniele R. Lima, Maria da Conceição L. Lima, Brenda Silva do Prado, Luiz Francisco Wemmenson Gonçalves Moura, Maria Izabel Florindo Guedes, Maria Kueirislene Amâncio Ferreira, Jane Eire Silva Alencar de Menezes, Sacha Aubrey Alves Rodrigues Santos, Francisco Rogênio da Silva Mendes, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro‐Moreira, Adriana Rolim Campos, Francisco Ernani Alves Magalhães,
Neem fruit (Azadirachta indica A. Juss.) are popularly used to treat infections, diarrhea, fever, bronchitis, skin diseases, infected burns and hypertension. Although the antinociceptive and anti-inflammatory potential of A. indica has already been investigated in experimental models of pain and inflammation in mice, the current research is the first to report the evaluation of the capacity of A. indica fruit ethanolic extract (EtFrNeem) in acute pain attenuation using the adult zebrafish (Danio rerio) ...
Tópico(s): Pain Mechanisms and Treatments
2018 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Francisca Crislândia Oliveira Silva, Jane Eire Silva Alencar de Menezes, Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Carlos Leone Alves Holanda, Joyce dos Reis Lima, Adriana Rolim Campos, Francisco Flávio Vasconcelos Evaristo, Edson Holanda Teixeira, Francisco Ernani Alves Magalhães, Paulo Nogueira Bandeira, Hélcio Silva dos Santos,
Drugs used to treat pain are associated with adverse effects, increasing the search for new drugs as an alternative treatment for pain. Therefore, we evaluated the antinociceptive behavior and possible neuromodulation mechanisms of triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene (CLF-1) isolated from Combretum leprosum leaves in zebrafish. Zebrafish (n = 6/group) were pretreated with CLF-1 (0.1 or 0.3 or 1.0 mg/mL; i.p.) and underwent nociception behavior tests. The antinociceptive effect of CFL-1 was ...
Tópico(s): Pain Mechanisms and Treatments
2020 - Elsevier BV | Biochemical and Biophysical Research Communications
Produção Nacional
Revisado por pares
Roseni Medeiro Lima, Francisco Meykel Amâncio Gomes, Francisca Alanny Rocha Aguiar, Edson Batista dos Santos Júnior, João Víctor Lira Dourado, Antônio Rodrigues Ferreira Júnior,
Objetivo: conhecer a experiência de mães durante a internação hospitalar de seus filhos. Métodos: Estudo descritivo-exploratório, com abordagem qualitativa em uma clínica pediátrica de um Hospital de referência na região norte do Ceará, Brasil, em novembro de 2015, com oito mães com filhos internados há pelo menos sete dias. A coleta das informações ocorreu por meio de entrevistas semiestruturada individual, que foram organizadas por meio da análise temática. Resultados: Configuraram-se quatro categorias ...
Tópico(s): Palliative and Oncologic Care
2019 - UNIVERSIDADE FEDERAL DO ESTADO DO RIO DE JANEIRO | Revista de Pesquisa Cuidado é Fundamental Online
Produção Nacional
Revisado por pares
Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Lucas Ramos Pereira, Emanuela L. Rebouças, Marnielle Rodrigues Coutinho, Joyce Dos, Reis Lima, Maria Izabel Florindo Guedes, Paulo Nogueira Bandeira, Francisco Ernani Alves Magalhães, Jane Eire Silva Alencar de Menezes, Márcia Machado Marinho, Alexandre Magno Rodrigues Teixeira, M. Trevisan, Hélcio Silva dos Santos, Emmanuel Silva Marinho,
Combretaceae are reported in the literature for presenting neuroprotective and anxiolytic effects in animal models. Combretum lanceolatum Pohl. has few scientific reports on its pharmacological effects. The aim of this study was to evaluate the anxiolytic and anticonvulsant effects of the ethanol extract from the leaves of C. lanceolatum Pohl. (EtFoCl) and its possible mechanism of GABAergic action in adult zebrafish. EtFoCl was subjected to determination of the total phenol concentration, identification ...
Tópico(s): Neuroscience and Neuropharmacology Research
2021 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Francisca Crislândia Oliveira Silva, Carlos Leone Alves Holanda, Sheila M. Barroso, Joyce dos Reis Lima, Antônio Eufrásio Vieira Neto, Adriana Rolim Campos, Paulo Nogueira Bandeira, Hélcio Silva dos Santos, Telma L. G. Lemos, Sônia Maria Costa Siqueira, Francisco Ernani Alves Magalhães, Jane Eire Silva Alencar de Menezes,
Benzodiazepines are the standard drugs for the treatment of anxiety, but their undesirable side effects make it necessary to develop new anxiolytic drugs. The objective of this study was to evaluate the possible anxiolytic-simile effect of synthetic chalcone N-{(4'-[(E)-3-(4-fluorophenyl)-1-(phenyl) prop-2-en-1-one]} acetamide (PAAPFBA) on adult zebrafish (Danio rerio). PAAPFBA was synthesized with an 88.21% yield and its chemical structure was determined by 1H and 13C NMR. Initially, animals (n = 6/ ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2019 - Elsevier BV | Behavioural Brain Research
Francisco Firmino dos Reis, Amâncio Carvalho, Célia Samarina de Brito Santos, Vítor Manuel Costa Pereira Rodrigues,
49,5%percepcionou o apoio social como suficiente, mas 36,2% apoio social insuficiente.A percepção do apoio social é menor nos sujeitos mais velhos (r = -0,166; p = 0,018).Conclusão: Este estudo permitiu perceber
Tópico(s): Migration, Identity, and Health
2014 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Produção Nacional
Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuela L. Rebouças, Francisca Crislândia Oliveira Silva, Carlos Leone Alves Holanda, Sheila M. Barroso, Joyce dos Reis Lima, Francisco Lucas Alves Batista, Francisco Rogênio da Silva Mendes, Adriana Rolim Campos, Jane Eire SA de Menezes, Francisco Ernani Alves Magalhães, Sônia Maria Costa Siqueira, Hélcio Silva dos Santos,
Azadirachta indica A. Juss is known as the tree of life for its diverse pharmacological applications.This study evaluated the effect of the anxiolytic type of bark of A. indica and mechanisms of action on adult zebrafish.Initially, EtCNeem toxicity was detected against Artemia salina, eliminated with the saponification reaction.The antioxidant potential of the fractions was evaluated.The fraction with higher antioxidant potential was submitted to the preliminary chemical prospecting, FT-IR, and ...
Tópico(s): Nanoporous metals and alloys
2020 - MedCrave Group | Pharmacy & Pharmacology International Journal
Produção Nacional
Revisado por pares
Cícero Úrban, Marcela Brisighelli Schaefer, Dakir Lourenço Duarte, Radiá Pereira dos Santos, Norma Médicis de Albuquerque Maranhão, Ana Lucia Kefalas, Ellyete de Oliveira Canella, Carlos Alberto Pecci Ferreira, João Emílio Peixoto, Luciano Fernandes Chala, Rodrigo Pepe Costa, José Luís Esteves Francisco, Simone Elias, Heverton Leal Ernesto de Amorim, Henrique Alberto Portella Pasqualette, Paulo Maurício Soares Pereira, Helio Sebastião Amâncio de Camargo, Vania Sondermann,
Mailing Address: Dra. Linei A. B. D. Urban. Rua Padre Agostinho, 913, ap. 53, Merces. Curitiba, PR, Brazil, 80430-050. E-mail: lineiurban@hotmail.com Urban LABD, Schaefer MB, Duarte DL, Santos RP, Maranhao NMA, Kefalas AL, Canella EO, Ferreira CAP, Peixoto JE, Chala LF, Costa RP, Francisco JLE, Martinelli SE, Amorim HLE, Pasqualette HA, Pereira PMS, Camargo Junior HSA, Sondermann VR. Recommendations of Colegio Brasileiro de Radiologia e Diagnostico por Imagem, Sociedade Brasileira de Mastologia, ...
Tópico(s): Breast Cancer Treatment Studies
2012 - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem | Radiologia Brasileira
Produção Nacional
Revisado por pares
Joyce dos Reis Lima, Maria Kueirislene Amâncio Ferreira, Ketelly Vanessa Barros Sales, Antônio Wlisses da Silva, Emanuelle Machado Marinho, Francisco Ernani Alves Magalhães, Emmanuel Silva Marinho, Márcia Machado Marinho, Matheus Nunes da Rocha, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Croton blanchetianus is known as 'marmeleiro preto', a very widespread shrub in Northeast Brazil. Terpenoids, steroids and phenolic compounds are among the reported secondary metabolites of the Croton genus that are a potential source of bioactive compounds. This study evaluated the anxiolytic potential of clerodine-type diterpene, sonderianin (CBWS) isolated from the stem bark of C. blanchetianus and its mechanism of action in adult zebrafish (Danio rerio) (ZFa). The anticonvulsant and anti-acetylcholinesterase ...
Tópico(s): Computational Drug Discovery Methods
2021 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Tatiana Rodrigues Garcia, P.T.C. Freire, Antônio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuela de Lima Rebouças, Francisco Rogênio da Silva Mendes, Emanuelle Machado Marinho, Márcia Machado Marinho, Alexandre Magno Rodrigues Teixeira, Emmanuel Silva Marinho, Paulo Nogueira Bandeira, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Anxiety and epilepsy affect millions of people worldwide, and the treatment of these pathologies involves the use of Benzodiazepines, drugs that have serious adverse effects such as dependence and sedation, so the discovery of new anxiolytic and antiepileptic drugs are necessary. Many routes for synthesizing ibuprofen derivatives have been developed, and these derivatives have shown promising pharmacological effects. Therefore, this study aims to evaluate its anxiolytic and anticonvulsant effect ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2023 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Emanuela de Lima Rebouças, Antônio Wlisses da Silva, Marnielle Coutinho Rodrigues, Maria Kueirislene Amâncio Ferreira, Francisco Rogênio da Silva Mendes, Márcia Machado Marinho, Emanuelle Machado Marinho, Lucas Ramos Pereira, José Ismael Feitosa de Araújo, José Ytalo Gomes da Silva, Luiz Francisco Wemmenson Gonçalves Moura, Francisco Ernani Alves Magalhães, Maria Tereza Salles Trevisan, Hélcio Silva dos Santos, Emmanuel Silva Marinho, Maria Izabel Florindo Guedes,
Turnera subulata Sm. belongs to the family Turneraceae and is found in Brazil. The present study evaluated the antinociceptive, anti-inflammatory, and hypoglycemic potential of T. subulata flower extract (EtFloTsu) in zebrafish (Danio rerio). The total phenol and flavonoid contents of EtFloTsu were determined and identified using the Folin Ciocalteu reagent and aluminum chloride (AlCl3), respectively. The constituents of the extract were identified by HPLC-DAD, and the in vitro antioxidant activity ( ...
Tópico(s): Biological and pharmacological studies of plants
2021 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Carlos Yago Pereira Batista, Y. Romaguera-Barcelay, Robert Saraiva Matos, Aline dos Santos Pedraça, Moisés do Amaral Amâncio, Ansoumane Kourouma, Y. Leyet, Eduardo Adriano Cotta, Walter Ricardo Brito, Ariamna María Dip Gandarilla, Marcus Valério Botelho do Nascimento, Francisco Xavier Nobre, Nilson S. Ferreira, Marco Salerno, Henrique Duarte da Fonseca Filho,
Herein, we report, for the first time, the reduction reaction kinetics of ciprofloxacin organic molecules based on structural and micromorphological conditions of an electrocatalytic system of Bi0.5Na0.5Ba(TiO3)2 (BNT-BT) thin films. XRD analysis showed the coexistence of rhombohedral and tetragonal structures for the BNT-BT thin films annealed at 600, 650, and 700 °C, showing that the first one had a greater number of surface defects, which Raman spectroscopy confirmed. Analysis of the 3D micromorphological ...
Tópico(s): Quantum Dots Synthesis And Properties
2023 - Elsevier BV | Applied Surface Science
Produção Nacional
Revisado por pares
Mikael Amaro de Souza, Kevin K.A. de Castro, Francisco Wagner Queiroz Almeida-Neto, Paulo Nogueira Bandeira, Maria Kueirislene Amâncio Ferreira, Márcia Machado Marinho, Matheus Nunes da Rocha, Débora Hellen Almeida de Brito, Francisco Rogênio da Silva Mendes, Tigressa Helena Soares Rodrigues, Mateus Rodrigues de Oliveira, Jane Eire Silva Alencar de Menezes, Antônio C.H. Barreto, Emmanuel Silva Marinho, Pedro de Lima‐Neto, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
Benzodiazepines (GABA receptor agonists) and serotonin reuptake inhibitors (SSRIs) are the drugs of choice for the treatment of anxiety. However, they have considerable adverse effects, so it is important to discover new anxiolytic agents. In this work, the 4′-[(1E,2E)-1-(2-(2′,4′-dinitrophenyl)hydrazone-3-(4-methoxyphenyl)allyl)aniline (HYDRAZDN) was synthesized and characterized by 1H and 13C NMR, 2D-NMR, ATR-FTIR, FT-Raman, and UV–Vis spectroscopy, and their structural and spectroscopic proprieties ...
Tópico(s): Photochromic and Fluorescence Chemistry
2021 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Tatiana Rodrigues Garcia, P.T.C. Freire, Paulo Nogueira Bandeira, Amanda Pereira de Sousa, Murilo Sérgio da Silva Julião, Tigressa Helena Soares Rodrigues, Márcia Machado Marinho, Emmanuel Silva Marinho, Francisco Wagner Queiroz Almeida-Neto, Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Jane Eire Silva Alencar de Menezes, Aldeneide Soares de Paiva, João Pedro da Hora, Antônio C.H. Barreto, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
In this work, an ibuprofen derivative 2-(4-isobutylphenyl) -N'-phenylpropanohydrazide (ACPHZN) was synthesized and characterized by NMR, ATR-FTIR, FT-Raman, and UV-Vis spectroscopy, while their structural and spectroscopic properties were investigated using DFT calculations. In vivo study using animal model in an adult Zebrafish (Danio rerio), and molecular docking was performed. In addition, molecular descriptors of the properties of absorption, distribution, metabolism and excretion, and toxicity ( ...
Tópico(s): Nonlinear Optical Materials Research
2021 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Antônia Jaqueline Nobre Bezerra, Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Pedro Henrique Ribeiro Lopes, Paulo Nogueira Bandeira, Hélcio Silva dos Santos, Francisco Ernani Alves Magalhães, Jane Eire Silva Alencar de Menezes,
Este trabalho busca a avaliacao da seguranca nao clinica do triterpeno AAA frente aos ensaios com zebrafish ( Danio rerio ) adulto. O triterpeno AAA foi isolado da raiz de Croton zehntneri . Solucoes desta substância foram preparadas com salina 0,9 %, nas concentracoes de (4,0 mg/kg ou 12 mg/kg ou 40 mg/kg; 20 μL i.p) e submetidas ao teste de toxicidade aguda frente ao modelo zebrafish. As mesmas doses foram investigadas quanto ao possivel efeito ansiolitico, atraves do teste de campo aberto. As tres dosagens ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2020 - Brazilian Journal of Development | Brazilian Journal of Development
Produção Nacional
Joyce dos Reis Lima, Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Carlos Leone Alves Holanda, Paulo Nogueira Bandeira, Hélcio Silva dos Santos, Francisco Ernani Alves Magalhães, Jane Eire Silva Alencar de Menezes,
Avaliação da segurança não clínica da chalcona (E)-1-(2-hidroxi-3,4,6trimetoxifenil)-3-(4-nitrofenil) prop-2-en-1-ona frente a zebrafish (Danio rerio) adulto Non-clinical safety assessment of chalcone (E) -1-(2-hydroxy-3,4,6trimethoxyphenyl) -3-(4-nitrophenyl)
Tópico(s): Mosquito-borne diseases and control
2020 - Brazilian Journal of Development | Brazilian Journal of Development
Produção Nacional
Mariana Luiza de Oliveira Santos, Williams Nascimento de Siqueira, José Luís Ferreira Sá, Luanna Ribeiro Santos Silva, Daniela Lyra de Vasconcelos Cabral, Francisco Fernandes Amâncio, Ana Maria Mendonça de Albuquerque Melo,
Ionizing radiation interacts with the environment may cause biological effects such as DNA damage, mutations in chromosomes and cell death. For this reason, it has currently researching the radioprotective effect of various substances, natural or synthetic, with the intention that the benefit brought by the therapeutic use of ionizing radiation is not outweighed by its harmful effects. Therefore, this study aims to investigate the possible radioprotective effect of the methanol extract of the bark ...
Tópico(s): Plant-Derived Bioactive Compounds
2013 - Associação Sergipana de Ciências | Scientia Plena
Produção Nacional
Revisado por pares
Larissa Santos Oliveira, Maria Kueirislene Amâncio Ferreira, Francisco Wagner Queiroz Almeida-Neto, Antônio Wlisses da Silva, José Ivo Lima Pinto Filho, Matheus Nunes da Rocha, Emanuelle Machado Marinho, Walber Henrique Ferreira Ribeiro, Márcia Machado Marinho, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos,
Abstract Background Anxiety disorders represent the complex interaction between biological, psychological, temperamental, and environmental factors; drugs available to treat anxiety such as benzodiazepines (BZDs) are associated with several unwanted side effects. Although there are useful treatments, there is still a need for more effective anxiolytics with better safety profiles than BZDs. Chalcones or 1,3‐diphenyl‐2‐proper‐1‐ones can be an alternative since this class of compounds has shown therapeutic ...
Tópico(s): Neuroscience and Neuropharmacology Research
2023 - Wiley | Fundamental and Clinical Pharmacology
Produção Nacional
Leonardo Santos Amâncio Cabral, Francisco Ricardo Lins Vieira de Melo,
O presente artigo tem como escopo principal apresentar, em base a dados de escala nacional, uma analise critica acerca da normatizacao e legitimacao do acesso e participacao do Publico-Alvo da Educacao Especial em Instituicoes de Ensino Superior. Considerando-se que as normativas vigentes, ao se depararem com a pluralidade politica, historica, economica, social e cultural, incidem a sua maneira sobre cada contexto, optou-se por realizar um estudo exploratorio no âmbito das cinco regioes brasileiras, ...
Tópico(s): Education Pedagogy and Practices
2017 - UNIVERSIDADE FEDERAL DO PARANÁ | Educar em Revista
Produção Nacional
Leonardo Mendes Amâncio, Weliston Luiz da Cruz Pereira da Silva, Vivianni Marques Leite dos Santos,
A desidratação pode ser utilizada para aumentar o tempo de consumo de frutas, bem como para aumentar os seus valores agregados. Esse procedimento está gradativamente chegando ao conhecimento dos produtores rurais do Vale do São Francisco. Com o desenvolvimento da tecnologia veio à liofilização, um processo de separação da água da fruta utilizando baixa temperatura e vácuo. A região do Vale do São Francisco é caracterizada pela grande produção de frutas ainda com grandes desperdícios durante o seu ...
Tópico(s): Banana Cultivation and Research
2012 - | Revista Semiárido De Visu
Edílson Silva de Araújo, Francisco Elionardo Amâncio, María de Felipe, Waldemir Lima dos Santos,
Este trabalho tem por finalidade mostrar como esta sendo degradada as margens do Rio Acre, em razao das dragas que atuam em Rio Branco, bem como contribuir para tomadas de decisoes dos gestores publicos ligados a questao ambiental, no sentido de empreender medidas que resultem na preservacao das margens do referido manancial. A verificacao in loco compreendeu a metodologia adotada para este trabalho, que foi desenvolvido a partir de expedicoes a campo, como parte das atividades praticas das disciplinas ...
Tópico(s): Geography and Environmental Studies
2019 - | UÁQUIRI - Revista do Programa de Pós Graduação em Geografia da Universidade Federal do Acre