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Artigo Revisado por pares

Francisco J. Ascaso, Laura Villén,

Ascaso, Francisco J MD, PhD; Villén, Laura PhDEditor(s): Toth, Cynthia A; Day, Shelley; Lin, Phoebe Author Information

Tópico(s): Retinal Diseases and Treatments

2011 - Lippincott Williams & Wilkins | Retina

Carta Revisado por pares

Valentín Huerva, Ramón Espinet, Francisco J. Ascaso,

... M.D., Ph.D.; Espinet, Ramón M.D.; Ascaso, Francisco J M.D., Ph.D. Author Information

Tópico(s): Intraocular Surgery and Lenses

2011 - Lippincott Williams & Wilkins | Eye & Contact Lens Science & Clinical Practice

Artigo Revisado por pares

Francisco J. Ascaso, Maria Rojo, E Mínguez, Steven M. Cohen, Sam S. Yang,

Ascaso, Francisco J; Rojo, Maria; Minguez, Enrique; Cohen, Steven M; Yang, Sam SEditor(s): McDonald, H Richard Author ...

Tópico(s): Hematological disorders and diagnostics

2011 - Lippincott Williams & Wilkins | Retina

Artigo Acesso aberto Revisado por pares

Patricia Udaondo, Alfredo Adán, Luís Arias, Francisco J. Ascaso, Francisco Cabrera López, Verónica Castro-Navarro, J. Donate-López, Alfredo García‐Layana, Francisco Javier Lavid, Mariano Rodríguez-Maqueda, José M. Ruiz‐Moreno,

This paper aimed to present daily-practice recommendations for the management of diabetic macular edema (DME) patients based on available scientific evidence and the clinical experience of the consensus panel.A group of Spanish retina experts agreed to discuss different aspects related with the clinical management of DME patients.Panel was mainly focused on therapeutic objectives in DME management; definition terms; and role of biomarkers as prognostic and predictive factors to intravitreal treatment ...

Tópico(s): Glaucoma and retinal disorders

2021 - Dove Medical Press | Clinical ophthalmology

Artigo Revisado por pares

Alfredo García‐Layana, Alfredo Adán, Francisco J. Ascaso, Francisco Cabrera López, J. Donate-López, Jose Juan Escobar-Barranco, G. Peralta, Rebeca Reyes‐García, Mariano Rodríguez Maqueda, José M. Ruiz‐Moreno, Irene Vinagre,

The aim of this study is to develop guidance on the use of intravitreal dexamethasone implants in the treatment of diabetic macular edema.The study was performed using the modified Delphi method to obtain a consensus among a panel of experts on management of patients with diabetic macular edema and use of intravitreal dexamethasone implants in clinical practice. Thirty-seven panel members, experts on retina, from different Spanish centers were invited to participate. Individual and anonymous opinions ...

Tópico(s): Retinal Imaging and Analysis

2019 - SAGE Publishing | European Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Francisco J. Ascaso,

... a Patient With Congenital Retinal Macrovessel Francisco J. Ascaso, MD, PhD Francisco J. AscasoFrancisco J. Ascaso From the Department of ... increased in patients with CSCR.DisclosuresNone.FootnotesCorrespondence to Francisco J. Ascaso, MD, Department of Ophthalmology, University Clinic Hospital, San ...

Tópico(s): Vascular Malformations Diagnosis and Treatment

2011 - Lippincott Williams & Wilkins | Circulation

Artigo Revisado por pares

Irene Lluch, Juan F. Ascaso, Francisco Mora, Miguel Mínguez, Andrés Peña, Antonio Hernández, A Benages,

OBJECTIVE: Although abnormal gastroesophageal (GE) reflux is the most frequent alteration of the gastrointestinal tract, its prevalence in diabetes mellitus (DM) is not widely known. The objective of this study was to analyze both the presence of abnormal GE reflux in diabetic patients with no esophageal symptoms and the influence of cardiovascular autonomic neuropathy (CVAN) in the development of abnormal GE reflux. METHODS: Fifty insulin-dependent diabetic patients, averaging 29.2 ± 9.0 yr of age, ...

Tópico(s): Gastrointestinal motility and disorders

1999 - Lippincott Williams & Wilkins | The American Journal of Gastroenterology

Artigo Revisado por pares

Irene Lluch, Juan F. Ascaso, Francisco Mora, Miguel Mínguez, Andrés Peña, Antonio Hernández, A Benages,

Although abnormal gastroesophageal (GE) reflux is the most frequent alteration of the gastrointestinal tract, its prevalence in diabetes mellitus (DM) is not widely known. The objective of this study was to analyze both the presence of abnormal GE reflux in diabetic patients with no esophageal symptoms and the influence of cardiovascular autonomic neuropathy (CVAN) in the development of abnormal GE reflux.Fifty insulin-dependent diabetic patients, averaging 29.2 +/- 9.0 yr of age, who had had diabetes ...

Tópico(s): Diet, Metabolism, and Disease

1999 - Lippincott Williams & Wilkins | The American Journal of Gastroenterology

Carta Revisado por pares

Alejandro Filloy, Luís Arias, Francisco J. Ascaso, J. Maria Caminal Mitjana,

... SpainSearch for more papers by this authorFrancisco J Ascaso MD PhD, Francisco J Ascaso MD PhD Ophthalmology Department, Clinic Hospital ... SpainSearch for more papers by this authorFrancisco J Ascaso MD PhD, Francisco J Ascaso MD PhD Ophthalmology Department, Clinic Hospital of Zaragoza, ...

Tópico(s): Ocular Oncology and Treatments

2016 - Wiley | Clinical and Experimental Ophthalmology

Artigo Revisado por pares

María José Ariza, José Rioja, Daiana Ibarretxe, Ana Camacho, José Luis Díaz-Díaz, Alipio Mangas, Julio A. Carbayo Herencia, Pablo Ruiz‐Ocaña, Itziar Lamíquiz-Moneo, Daniel Mosquera, Pedro Luis Ruíz Sáenz, L. Masana, Ovidio Muñiz-Grijalvo, Sofía Pérez‐Calahorra, Pedro Valdivielso, Manuel Suárez Tembra, Gonzalo Pías Iglesias, Julio A. Carbayo Herencia, C. Guerrero Buitrago, Luis M. Vilá, Camila Coca, E. Llargués Rocabruna, V. Perea Castillo, J Pedro‐Botet, Elisenda Climent, Marta Mauri, Xavier Pintó, E. Ortega Martínez de la Victoria, J Amor, Danijela Rados, Francisco Blanco‐Vaca, José M. Lozano, F.J. Fuentes Jiménez, Isabel Orea Soler, Cláudia Ferrer, Alexandra Cervantes, Ά. Belmonte, F.J. Novoa Mogollón, Rosa M. Sanchez-Hernández, A.B. Expósito Montesdeoca, Manuel Romero, M.P. González García, Marta Bueno, Ángel Brea Hernando, Carlos Lahoz, José M. Mostaza Prieto, Jesús Millán Núñez-Cortés, L. Reinares García, Agustín Blanco Echevarría, María José Ariza, José Rioja, Miguel Ángel Sánchez-Chaparro, S. Jansen Chaparro, Pedro Sáenz de Aranzubía, Emilia Mateu, Fernándo Múgica, Ovidio Muñiz Grijalvo, Lynn Martin, Núria Plana, Daiana Ibarretxe Gerediaga, Cèlia Rodríguez-Borjabad, Sabine Lopez, Antonio Hernández‐Mijares, Juan Francisco Ascaso Gimilio, Lourdes Pérez García, Fernando Civeira Murillo, Sofía Pérez‐Calahorra, I. Lamiquiz-Moneo, Rocío Gallego‐Durán, V. Marco Benedí, Juan Ferrando Vela,

Tópico(s): Cancer, Lipids, and Metabolism

2018 - Elsevier BV | Journal of clinical lipidology

Artigo Acesso aberto

Jesús Millán Núñez-Cortés, Aleix Cases, Juan Francisco Ascaso Gimilio, Vivencio Barrios, Vicente Pascual Fuster, Juan Carles Pedro-Botet Montoya, Xavier Pintó, A. Serrano Cumplido,

Despite the recognized clinical benefit of statins on cardiovascular prevention, providing correct management of hypercholesterolaemia, possible adverse effects of their use cannot be disregarded. Previously published data shows that there is a risk of developing diabetes mellitus or experiencing changes in glucose metabolism in statin-treated patients. The possible determining factors are the drug characteristics (potency, dose), patient characteristics (kidney function, age, cardiovascular risk ...

Tópico(s): Pharmaceutical Practices and Patient Outcomes

2016 - Adis, Springer Healthcare | American Journal of Cardiovascular Drugs

Artigo Acesso aberto Revisado por pares

Francisco J. Ascaso, L CABEZON, Marı́a Elena Quintanilla, Leticia Gutiérrez Galve, Raúl López‐Antón, José Á. Cristóbal, António Lobo,

... reveal differences between both groups.No statisti-228 FRANCISCO J. ASCASO ET AL. cally significant differences were observed between ...

Tópico(s): Retinal Development and Disorders

2010 - Elsevier BV | The European Journal of Psychiatry

Artigo Revisado por pares

Francisco J. Ascaso, Jesús Castillo, Francisco J. García, José Á. Cristóbal, Ana María de Caso Fuertes, Á. Artal,

Choroidal metastases are metastatic lesions to the choroid layer of the eye. Although infrequent, they may be the initial manifestation of lung cancer. To date, only 10 cases of choroidal metastasis as the first sign of lung carcinoma have been reported. We present a 42-year-old woman with choroidal metastasis as the initial manifestation of an advanced lung carcinoma. Choroidal metastases are metastatic lesions to the choroid layer of the eye. Although infrequent, they may be the initial manifestation ...

Tópico(s): Ocular Diseases and Behçet’s Syndrome

2009 - Elsevier BV | The Annals of Thoracic Surgery

Artigo Revisado por pares

José Luis Palma Gámiz, Ignacio Conget Donlo, Vicente Bertomeu‐González, Juan Francisco Ascaso Gimilio, José Ramón González‐Juanatey, Eduardo Alegría Ezquerra, Pedro Conthe Gutiérrez, Hermenegildo de la Calle Blasco, Manuel Serrano‐Ríos,

To assess the prevalence of metabolic syndrome (MS) and cardiovascular risk factors in patients with established cardiovascular disease (CVD).Epidemiologic, cross-sectional, multicentre and national study. 1,342 evaluable patients were recruited by 95 physicians of primary care, cardiology, endocrinology and internal medicine. All patients had confirmed diagnosis of CVD (myocardial infarction, coronary disease, ischaemic cerebrovascular disease and/or peripheral vascular disease) and analytical data ...

Tópico(s): Health and Lifestyle Studies

2007 - Elsevier BV | Medicina Clínica

Revisão Revisado por pares

Francisco J. Ascaso, MARÍA T. TIESTOS, JOSEFINA NAVALES, FRANCISCO ITURBE, Alejandro Reynoso Palomar, JOSÉ I. AYALA,

Since its introduction, fluorescein angiography has been widely used to investigate diseases of the ocular fundus. A case of fatal acute myocardial infarction after intravenous fluorescein angiography is presented. This appears to be the first case documented by autopsy in which the findings are compatible with myocardial infarction as the cause of death. Although there are no known contraindications for fluorescein angiography in patients with a history of cardiovascular disease, the indications ...

Tópico(s): Glaucoma and retinal disorders

1993 - Lippincott Williams & Wilkins | Retina

Artigo Acesso aberto Revisado por pares

José Tomás Real Collado, Manuel Valls, M.L. Basanta Alario, Francisco Javier Ampudia‐Blasco, Juan Francisco Ascaso Gimilio, Rafael Carmena Rodríguez,

INTRODUCCIÓNLa diabetes mellitus (DM) es un importante problema de Salud Pública por su elevada prevalencia y morbimortalidad (1).En los Estados Unidos representa la mayor causa de morbilidad, mortalidad y de gasto económico (1-5).Los pacientes diabéticos tienen un elevado riesgo de padecer complicaciones crónicas cardiovasculares, renales, oftalmológicas, neurológicas y podológicas cuya incidencia crece anualmente (6-9).En el año 1994 el coste directo por diabetes en España fue de 90.000 millones de ...

Tópico(s): Wound Healing and Treatments

2001 - SciELO | Anales de Medicina Interna

Artigo Brasil Produção Nacional Revisado por pares

Sami H. Uwaydat, Ahmad M. Mansour, Francisco J. Ascaso, Maurízio Battaglia Parodi, Robert E. Foster, William E. Smiddy, Stephen G. Schwartz, Abdulrazzak Charbaji, Silvana Belotto, Ignasi Jürgens, Javier Mateo, Abdallah A. Ellabban, Lihteh Wu, Marta S. Figueroa, Nuria Olivier Pascual, Luiz H. Lima, Wael A. Alsakran, Sibel Kadayıfçılar, Suthasinee Sinawat, Alexandre Assi, Hana A. Mansour, Antonio M B Casella, Amparo Návea, Elena Rodríguez Neila, Ali Osman Saatçi, Vishal Govindahari, O. Estebán Floría, Komal Agarwal, Ismael Bakkali El Bakkali, Angel Salinas Alaman, Sofia Fernandez Larripa, Amanda Rey, Patricia Pera, Lluís Bruix, Lorenzo López-Guajardo, Eduardo Pérez-Salvador, Francisco Javier Lara Medina, Frank N. Hrisomalos, Jay Chhablani, J. Fernando Arévalo,

To ascertain the anatomic factors that help achieve non-surgical sealing in full thickness macular hole (FTMH).Retrospective collaborative study of FTMH that closed without surgical intervention.A total of 78 patients (mean age 57.9 years) included 18 patients with blunt ocular trauma, 18 patients that received topical or intravitreal therapies and 42 patients with idiopathic FTMH. Mean±SD of the initial corrected visual acuity (VA) in logMAR improved from 0.65±0.54 to 0.34±0.45 (p<0.001) at a mean ...

Tópico(s): Intraocular Surgery and Lenses

2021 - BMJ | British Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Sara Llorente‐González, María Hernández, Jorge González‐Zamora, Valentina Bilbao‐Malavé, Patricia Fernández‐Robredo, Manuel Sáenz de Viteri, Jesús Barrio‐Barrio, María José Rodríguez‐Cid, J. Donate-López, Francisco J. Ascaso, Ana Gómez‐Ramírez, Javier Araiz, Félix Armadá, Óscar Ruiz‐Moreno, Sergio Recalde, Alfredo García‐Layana,

Abstract Purpose To assess the effect of clinical factors on the development and progression of atrophy and fibrosis in patients with neovascular age‐related macular degeneration (nAMD) receiving long‐term treatment in the real world. Methods An ambispective 36‐month multicentre study, involving 359 nAMD patients from 17 Spanish hospitals treated according to the Spanish Vitreoretinal Society guidelines, was designed. The influence of demographic and clinical factors, including the presence and location ...

Tópico(s): Retinal and Optic Conditions

2021 - Wiley | Acta Ophthalmologica

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ahmad M. Mansour, Igor Kozák, Ali Osman Saatçi, Francisco J. Ascaso, Laura Broc, Maurízio Battaglia Parodi, Nuria Olivier Pascual, Pablo Gili, Jay Chhablani, Thomas R. Hedges, Ana Honrubia, Lourdes De Avila Gutierrez, Giacomo Panozzo, Jaume Catalá, Jesús Díaz, Elisa Carreras, Sibel Kadayıfçılar, Eman Saeed Kahtani, Sami H. Uwaydat, Luiz H. Lima, Hana A. Mansour, Hashim Ali Khan, Thomas M. Aaberg, Jerald A. Bovino, Alex P. Hunyor,

To analyze the ophthalmic characteristics of congenital prepapillary vascular loop (PVL) and to propose a new morphologic classification dividing the loops into six types.Collaborative multinational multicentre retrospective study of PVL cases.There was a total of 49 cases (61 eyes), 37 unilateral (75.5%) and 12 bilateral (24.5%), 32 arterial type (65.3%) and 18 venous type (36.7%) (one patient had either kind in each eye). The mean number of loops per eye was 2.7 (range, 1-7). The loops were asymptomatic ...

Tópico(s): Retinal Imaging and Analysis

2020 - Springer Nature | Eye

Revisão Revisado por pares

Cristina Pont, Francisco J. Ascaso, Andrzej Grzybowski, Valentín Huerva,

Diabetes mellitus may affect the cornea at various levels. Ocular surface changes and dry eye had been studied. Researchers are concerned that medical treatment of diabetes or retinal complications may result in endothelial damage and cell loss. This report summarizes the possibility of endothelial cell loss in diabetic patients. A decrease in endothelial cell density (ECD) in diabetic patients has been reported. In addition, corneal thickness may increase in diabetic patients. Significant endothelial ...

Tópico(s): Corneal surgery and disorders

2020 - Elsevier BV | Journal Français d Ophtalmologie

Revisão Acesso aberto Revisado por pares

Andrzej Grzybowski, Piotr Kanclerz, Valentín Huerva, Francisco J. Ascaso, Raimo Tuuminen,

Diabetes mellitus is one of the most prevalent chronic diseases worldwide. Diabetic patients are at risk of developing cataract and present for surgery at an earlier age than non-diabetics. The aim of this study was to review the problems associated with cataract surgery in a diabetic patient. Corneal complications in diabetic patients include delayed wound healing, risk of developing epithelial defects or recurrent erosions due to the impairment of epithelial basement membranes and epithelial–stromal ...

Tópico(s): Intraocular Surgery and Lenses

2019 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine

Revisão Acesso aberto Revisado por pares

M.Á. Del Buey, P CASAS, C Caramello, Nuria López, Marisa de la Rica, Ana B. Subirón, Elena Lanchares, Valentín Huerva, Andrzej Grzybowski, Francisco J. Ascaso,

In the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the main and most widely recognized ocular effect of diabetes is on the retina, the structure of the cornea (the outermost and transparent tissue of the eye) can also be affected by the poor glycemic control ...

Tópico(s): Corneal Surgery and Treatments

2019 - Hindawi Publishing Corporation | Journal of Ophthalmology

Revisão Acesso aberto Revisado por pares

Francisco J. Ascaso, Sara Marco, Javier Mateo, Mireya Martínez, O. Esteban, Andrzej Grzybowski,

Migraine is a chronic disease characterized by unilateral, pulsating, and often moderate-to-severe recurrent episodes of headache with nausea and vomiting. It affects approximately 15% of the general population, yet the underlying pathophysiological mechanisms are not fully understood. Optical coherence tomography (OCT) is a safe and reproducible diagnostic technique that utilizes infrared wavelengths and has a sensitivity of 8-10 μm. It can be used to measure thinning of the retinal nerve fiber ...

Tópico(s): Cerebral Venous Sinus Thrombosis

2017 - Frontiers Media | Frontiers in Neurology

Artigo Acesso aberto Revisado por pares

Elena García‐Martín, Javier Garcı́a-Campayo, Marta Puebla‐Guedea, Francisco J. Ascaso, Miquel Roca, Fernando Gutierrez-Ruiz, Elisa Viladés, Vicente Polo, José M. Larrosa, Luís E. Pablo, María Satué,

To investigate whether fibromyalgia induces axonal damage in the optic nerve that can be detected using optical coherence tomography (OCT), as the retinal nerve fiber layer (RNFL) is atrophied in patients with fibromyalgia compared with controls.Fibromyalgia patients (n = 116) and age-matched healthy controls (n = 144) were included in this observational and prospective cohort study. All subjects underwent visual acuity measurement and structural analysis of the RNFL using two OCT devices (Cirrus and Spectralis). ...

Tópico(s): Effects of Vibration on Health

2016 - Public Library of Science | PLoS ONE

Revisão Acesso aberto Revisado por pares

Andrzej Grzybowski, Bartosz L. Sikorski, Francisco J. Ascaso, Valentín Huerva,

Abstract: Pseudophakic cystoid macular edema (PCME) is the most common complication of cataract surgery, leading in some cases to a decrease in vision. Although the pathogenesis of PCME is not completely understood, the contribution of postsurgical inflammation is generally accepted. Consequently, anti-inflammatory medicines, including steroids and nonsteroidal anti-inflammatory drugs, have been postulated as having a role in both the prophylaxis and treatment of PCME. However, the lack of a uniformly ...

Tópico(s): Ocular Diseases and Behçet’s Syndrome

2016 - Dove Medical Press | Clinical Interventions in Aging

Revisão Revisado por pares

Francisco J. Ascaso, Valentín Huerva,

The incidence of diabetes mellitus is dramatically increasing in the developed countries. Tight control of blood glucose concentration is crucial to diabetic patients to prevent microvascular complications. Self-monitoring of blood glucose is widely used for controlling blood glucose levels and usually performed by an invasive test using a portable glucometer. Many technologies have been developed over the past decades with the purpose of obtaining a continuous physiological glycemic monitoring. ...

Tópico(s): Advanced Biosensing Techniques and Applications

2015 - Lippincott Williams & Wilkins | Optometry and Vision Science

Artigo Revisado por pares

Francisco J. Ascaso, Roberto Rodríguez‐Jiménez, L CABEZON, Raúl López‐Antón, Javier Santabárbara, Concepción de la Cámara, Pedro J. Modrego, Marı́a Elena Quintanilla, Alexandra Bagney, Letícia Gutiérrez de Gutiérrez, N CRUZ, José Á. Cristóbal, António Lobo,

Optical coherence tomography (OCT) has been recently used to investigate neuropsychiatric disorders. We aimed to study retinal OCT measures of patients with schizophrenia with respect to healthy controls, and to evaluate possible differences between recent illness episode (RIE) and non-recent illness episode (NRIE) patients. Thirty schizophrenia patients were classified as RIE (n=10) or NRIE (n=20), and compared with 30 matched controls. Statistical analyses included linear mixed-effects models to study ...

Tópico(s): Retinal Diseases and Treatments

2015 - Elsevier BV | Psychiatry Research

Revisão Acesso aberto Revisado por pares

Francisco J. Ascaso, Valentín Huerva, Andrzej Grzybowski,

Posterior chamber intraocular lens (PC-IOL) subluxation is uncommon but represents one of the most serious complications following phacoemulsification. Late spontaneous IOL-capsular bag complex dislocation is defined as occurring three months or later following cataract surgery. Unlike early IOL dislocation, late spontaneous IOL dislocation is due to a progressive zonular dehiscence and contraction of the capsular bag many years what seemed to be uneventful surgery. In recent years, late in-the-bag ...

Tópico(s): Retinal and Macular Surgery

2015 - Hindawi Publishing Corporation | Journal of Ophthalmology

Revisão Acesso aberto Revisado por pares

Francisco J. Ascaso, Valentín Huerva, Andrzej Grzybowski,

Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells.

Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms

2014 - Hindawi Publishing Corporation | Mediators of Inflammation