Produção Nacional
Revisado por pares
Lucas Dall Agnol, Heitor Luiz Ornaghi, Francisco Maciel Monticeli, Fernanda Trindade Gonzalez Dias, Otávio Bianchi,
Abstract The molar mass of the polyurethanes (PUs)' reagents directly influences their thermal response, affecting both the polymerization process and the enthalpy and the degree of reaction. This study reports applying an artificial neural network (ANN), associated with surface response methodology (SRM) models, to predict the calorimetric behavior of certain PU's bulk polymerizations. A noncatalyzed reaction between an aliphatic hexamethylene diisocyanate (HDI) and a polycarbonate diol (PCD) with distinct ...
Tópico(s): Epoxy Resin Curing Processes
2021 - Wiley | Polymer Engineering and Science
María Isabel Prudêncio, María Isabel Dias, João C. Waerenborgh, Francisco Ruiz Muñoz, M.J. Trindade, Manuel Abad, Rosa Marques, M.A. Gouveia,
Tópico(s): earthquake and tectonic studies
2011 - Elsevier BV | CATENA
Produção Nacional
Revisado por pares
Marcelo Demarzo, Rodrigo Cariri Chalegre de Almeida, João José Neves Marins, Thiago Gomes da Trindade, Maria Inêz Padula Anderson, Aírton Tetelbom Stein, Fabiano Gonçalves Guimarães, Felipe Proenço de Oliveira, Fernanda Plesmann de Carvalho, Flávio Dias Silva, Francisco Arsego de Oliveira, Gustavo Tenório Carlos, Jaciara Bezerra Marques, Leika Aparecida Ishigama Geniole, Lia Márcia Cruz da Silveira, Maria Eugênia Bresolin Pinto, Nayra Almeida da Silva, Rodrigo Cechelero Bagatelli, Sandro Rodrigues Batista, Tânia de Araújo Barboza, Thiago Dias Sarti, Vitor Hugo Lima Barreto, Gustavo Gusso, Mourad Ibrahim Belaciano,
O presente documento traz diretrizes construídas conjuntamente pela Associação Brasileira de Educação Médica (ABEM) e a Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC) com a intenção de apoiar as escolas médicas de forma objetiva e prática, na elaboração de projetos político-pedagógicos no contexto da Atenção Primária à Saúde. Um marco reconhecido na política educacional brasileira é a publicação das Diretrizes Curriculares Nacionais, as quais flexibilizam as organizações curriculares, ...
Tópico(s): Male Reproductive Health Studies
2012 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Cláudia Camila Dias, Mafalda Santiago, L Correia, Francisco Portela, Paula Ministro, Paula Lago, Eunice Trindade, Alberto Freitas, Fernando Magro,
In this study, we aimed to determine the hospitalization rates of Inflammatory Bowel Disease (IBD) in a southern-european country and its associated charges over a period of 16 years.We identified all discharges with a primary diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) between 2000 and 2015 in data provided by the Central Administration of Health Services (ACSS). National estimates of hospitalization rates were assessed and adjusted to gender, age, population, and hospitalizations. ...
Tópico(s): Eosinophilic Esophagitis
2019 - Elsevier BV | Digestive and Liver Disease
Produção Nacional
Revisado por pares
Marcelo Demarzo, Rodrigo Cariri Chalegre de Almeida, João José Neves Marins, Thiago Gomes da Trindade, Maria Inêz Padula Anderson, Aírton Tetelbom Stein, Marcelo Rodrigues Gonçalves, Felipe Proenço de Oliveira, Fernanda Plesmann de Carvalho, Flávio Dias Silva, Francisco Arsego de Oliveira, Gustavo Tenório Carlos, Jaciara Bezerra Marques, Leika Aparecida Ishigama Geniole, Lia Márcia Cruz da Silveira, Maria Eugênia Bresolin Pinto, Nayra Almeida da Silva, Rodrigo Cechelero Bagatelli, Sandro Rodrigues Batista, Tânia de Araújo Barboza, Thiago Dias Sarti, Vitor Hugo Lima Barreto, Gustavo Gusso, Mourad Ibrahim Belaciano,
O presente documento traz diretrizes construídas conjuntamente pela Associação Brasileira de Educação Médica (ABEM) e a Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC) com a intenção de apoiar as escolas médicas de forma objetiva e prática, na elaboração de projetos político-pedagógicos no contexto da Atenção Primária à Saúde. Um marco reconhecido na política educacional brasileira é a publicação das Diretrizes Curriculares Nacionais, as quais flexibilizam as organizações curriculares, ...
Tópico(s): Women's cancer prevention and management
2011 - | Revista Brasileira de Medicina de Família e Comunidade
Mafalda Santiago, Francisco Stocker, Paula Ministro, Raquel Gonçalves, Diana Carvalho, Francisco Portela, L Correia, Paula Lago, Eunice Trindade, Cláudia Camila Dias, Fernando Magro,
INTRODUCTION: Inflammatory bowel disease (IBD) affects people from all age categories worldwide. Although the incidence of the disease is stabilizing or decreasing in most Western world countries, its prevalence is still increasing because of the rise in life expectancy and better disease management. This work intends to identify the trends related to IBD incidence nationwide, analyzing regional, sex, and age distributions. METHODS: Data were provided by the Portuguese Shared Services of the Ministry ...
Tópico(s): Microscopic Colitis
2022 - Lippincott Williams & Wilkins | Clinical and Translational Gastroenterology
Produção Nacional
Revisado por pares
Larissa Quinto Pereira, Ricardo de Francisco Strefezzi, José Luiz Catão‐Dias, Michele Martins Trindade, Rafael A. Fighera, Glaucia D. Kommers, Maristela Lovato,
Alimentary habits of free-living Psittaciformes vary significantly among different species. Amazona pretrei is under risk of extinction and has very specific free-living dietary habits, which are based on Paraná pine seeds. Hemosiderosis is a pathologic process characterized by intracellular accumulation of iron without other evident lesions. It is associated with increased prevalence of infections, neoplasms, and hepatopathies. The purpose of this study was to quantify hepatic hemosiderin deposits ...
Tópico(s): Parasite Biology and Host Interactions
2010 - American Association of Avian Pathologists | Avian Diseases
Produção Nacional
Revisado por pares
Geovane Dias-Lopes, Leonardo Sabóia‐Vahia, Eliane Trindade Margotti, Nilma de Souza Fernandes, Cássia Luana de Faria Castro, Francisco Odêncio Rodrigues de Oliveira, Juliana Figueiredo Peixoto, Constança Britto, Fernando Costa e Silva Filho, Patrícia Cuervo, José Batista de Jesus,
Trichomonas vaginalis is the aetiological agent of human trichomoniasis, which is one of the most prevalent sexually transmitted diseases in humans. Iron is an important element for the survival of this parasite and the colonisation of the host urogenital tract.In this study, we investigated the effects of iron on parasite proliferation in the dynamics of pseudocyst formation and morphologically characterised iron depletion-induced pseudocysts.We performed structural and ultrastructural analyses ...
Tópico(s): Amoebic Infections and Treatments
2017 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Wellington Francisco Rodrigues, Mila Fernandes Moreira Madeira, TA da Silva, Juliana Trindade Clemente‐Napimoga, CB Miguel, Valdo J. Dias-da-Silva, Octávio Barbosa Neto, Alexandre H. Lopes, Marcelo Henrique Napimoga,
Bones are widely innervated, suggesting an important role for the sympathetic regulation of bone metabolism, although there are controversial studies. We investigated the effects of propranolol in a model of experimental periodontal disease.Rats were assigned as follows: animals without ligature; ligated animals receiving vehicle and ligated animals receiving 0.1, 5 or 20 mg·kg(-1) propranolol. After 30 days, haemodynamic parameters were measured by cardiac catheterization. Gingival tissues were ...
Tópico(s): Bone health and treatments
2011 - Wiley | British Journal of Pharmacology
Carla Real, Leonor Remédio, Francisco Caiado, Cátia Igreja, Cristina Borges, Alexandre Trindade, Perpétua Pinto‐do‐Ó, Hideo Yagita∥, António Duarte, Sérgio Dias,
Neo-blood vessel growth (angiogenesis), which may involve the activation of pre-existing endothelial cells (EC) and/or the recruitment of bone marrow-derived vascular precursor cells (BM-VPC), is essential for tumor growth. Molecularly, besides the well established roles for Vascular endothelial growth factor (VEGF), recent findings show the Notch signalling pathway, in particular the ligand Delta-like 4 (Dll4), is also essential for adequate tumor angiogenesis; Dll4 inhibition results in impaired, non- ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2011 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Ingred Gimenes Cassimiro de Freitas, Cássio de Almeida Lima, Viviane Maia Santos, Francisco Trindade Silva, Josiane Santos Brant Rocha, Orlene Veloso Dias, Rosângela Ramos Veloso Silva, Maria Fernanda Santos Figueiredo Brito,
This research aimed to assess the level of physical activity and identify the associated factors in pregnant women assisted in primary health care in the city of Montes Claros, Minas Gerais (Brazil). This was an epidemiological, cross-sectional, analytical study, carried out with 1,279 pregnant women. Socioeconomic, occupational, obstetric, behavioral, social, health, and emotional variables were assessed using a questionnaire. The Physical Activity Questionnaire for Pregnant Women was also applied. ...
Tópico(s): Physical Activity and Health
2022 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Aline C. M. Sobreira, Francisco das Chagas Lima Pinto, Katharine Gurgel Dias Florêncio, Diego Veras Wilke, Charley Christian Staats, Rodrigo de A. S. Streit, Francisco das Chagas de O. Freire, Otília Deusdênia Loiola Pessoa, Amaro E. Trindade‐Silva, Kirley Marques Canuto,
In the present study, we integrated liquid chromatography high-resolution mass spectrometry (LC-HRMS) and high-throughput DNA sequencing for prospecting cytotoxic specialized metabolites from Pseudofusicoccum stromaticum, an endophytic fungus associated to the medicinal plant Myracrodruon urundeuva. LC-HRMS profiling allowed identifying putatively eleven compounds in the ethyl acetate extract from P. stromaticum broth. Additionally, a chemical fractionation guided by cytotoxicity combined with spectrometric ...
Tópico(s): Plant Gene Expression Analysis
2018 - Royal Society of Chemistry | RSC Advances
Produção Nacional
Revisado por pares
Lucas C. Pantaleão, Gabriela Fullin Resende Teodoro, Francisco Leonardo Torres‐Leal, Daiana Vianna, Tatyana Dias de Paula, Emídio Marques de Matos‐Neto, Michele Caroline de Costa Trindade, Marcelo Macedo Rogero, Carlos Roberto Bueno Júnior, Júlio Tirapegui,
The positive regulation of insulin pathway in skeletal muscle results in increased activity of the mammalian target of rapamycin (mTOR), a positive effector of mRNA translation rate and protein synthesis. Studies that assess the activity of this protein in response to chronic high-fat diet (HFD) are scarce and controversial, and to date, there are no studies evaluating the mTOR pathway in infants exposed to gestational and postgestational HFD. This study investigated the effect of maternal HFD on ...
Tópico(s): Adipose Tissue and Metabolism
2013 - Elsevier BV | The Journal of Nutritional Biochemistry
Sandra Trindade, Filipa Rijo‐Ferreira, Tânia Carvalho, Daniel Pinto‐Neves, Fabien Guegan, Francisco Aresta‐Branco, Fábio Bento, Simon A. Young, Andreia Pinto, Jan Van Den Abbeele, Ruy M. Ribeiro, Sérgio Dias, Terry Smith, Luísa M. Figueiredo,
Trypanosoma brucei is an extracellular parasite that causes sleeping sickness. In mammalian hosts, trypanosomes are thought to exist in two major niches: early in infection, they populate the blood; later, they breach the blood-brain barrier. Working with a well-established mouse model, we discovered that adipose tissue constitutes a third major reservoir for T. brucei. Parasites from adipose tissue, here termed adipose tissue forms (ATFs), can replicate and were capable of infecting a naive animal. ...
Tópico(s): Research on Leishmaniasis Studies
2016 - Cell Press | Cell Host & Microbe
Produção Nacional
Revisado por pares
Lucas Solyano Almeida de Oliveira, Sara Raquel de Moura Bandeira, Rodrigo Lopes Gomes Gonçalves, Benedito Pereira de Sousa Neto, Diana Carvalho de Rezende, Antonio Carlos dos Reis-Filho, Ian Jhemes Oliveira Sousa, Flaviano Ribeiro Pinheiro-Neto, Boris Timah, Gabriela do Nascimento Caldas Trindade, Lázaro Gomes do Nascimento, Damião Pergentino de Sousa, Fernanda Regina de Castro Almeida, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Francisco de Assis Oliveira,
Hemorrhagic cystitis is the main adverse effect associated with the clinical use of oxazaphosphorine, resulting in increased oxidative stress and proinflammatory cytokines, which culminate in injury of the bladder tissue. The aim of this study was to evaluate the protective effect of isopropyl gallate (IPG) against ifosfamide (IFOS)-induced hemorrhagic cystitis in mice. The induction of the hemorrhagic cystitis model was carried out using a single dose of IFOS (400 mg/kg, i.p.) four hours after oral ...
Tópico(s): Hematopoietic Stem Cell Transplantation
2022 - Multidisciplinary Digital Publishing Institute | Biology
Produção Nacional
Sérgio Neto, César Casarolli, Luiz Henrique Dias Sandon, Vinícius Trindade Gomes da Silva, Francisco Ureña, Nilton Caetano da Rosa, Manoel Jacobsen Teixeira, Marcos Queirós Teles Gomes,
The coexistence of meningioma and schwannoma as two distinct components within the same tumor is extremely rare.They are usually associated with Type 2 Neurofibromatosis (NF-2) but there are some isolated reports of cases without confirmed diagnosis or in association with cancer and/or post irradiation cancer patients.The authors present a case of a collision tumor of the CPA with a presumed diagnosis of NF-2 and a literature review.
Tópico(s): Adrenal and Paraganglionic Tumors
2016 - | Journal of Pain Management & Medicine
Mafalda Santiago, Fernando Magro, L Correia, Francisco Portela, Paula Ministro, Paula Lago, Eunice Trindade, Cláudia Camila Dias,
Despite the recent emergence of expensive biologic therapies, hospitalization and surgery remain important contributors for the overall costs of inflammatory bowel disease (IBD). In this study, we aimed to describe the burden of reoperations in patients with IBD by evaluating reoperation rates, charges, and risk factors over 16 years.We performed a retrospective analysis of all hospital discharges, with focus on reoperations and with a primary diagnosis of IBD, in public hospitals between 2000 and ...
Tópico(s): Diagnosis and treatment of tuberculosis
2020 - Lippincott Williams & Wilkins | Clinical and Translational Gastroenterology
Tribunal Federal de Recursos
Tópico(s): Academic Research in Diverse Fields
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): Brazilian Legal Issues
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): Brazilian Legal Issues
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): Digital Rights Management and Security
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Produção Nacional
Tribunal Federal de Recursos
Tópico(s): Public Procurement and Policy
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): International Environmental Law and Policies
1987 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): Business and Management Studies
1986 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Tribunal Federal de Recursos
Tópico(s): Education and Public Policy
1986 - Fundacao Getulio Varagas | Revista de Direito Administrativo
Ana Margarida Medeiros, Ana Catarina Alves, Beatriz Miranda, Joana Rita Chora, Mafalda Bourbon, Mafalda Bourbon, Quitéria Rato, Ana Catarina Alves, Ana Margarida Medeiros, Ana Catarina Gomes, Ana Cristina Ferreira, Ana Maria Minarelli Gaspar, Ana Marques, Ana Garabal, Ana Paula Bogalho, Ana Rita Pereira, Anabela Raimundo, André Travessa, Andreia Lopes, António Afonso, António Furtado, António Guerra, António M. Monteiro, António Trindade, Armindo Ribeiro, Bernardo Dias Pereira, Bernardo Marques, Carla Laranjeira, Catarina Moniz, Cecília Frutuoso, C Reis, Cláudia Rodrigues, Clementina Fernandes, Conceição Ferreira, Daniel Correia Freire Ferreira, Diogo Torres, Elisabete Martins, Elsa Gaspar, Fabiana Pimentel, Fernando Dias Simões, Francisco Araújo, F.J.G. Silva, Goreti Lobarinhas, Graça Morais, Guida Gama, Guilherme Lourenço, Helena Ferreira Mansilha, Héléna Pereira, Heloísa G. dos Santos, Henedina Antunes, Inês Batista Gomes, Inês Colaço, Isabel Azevedo, Isabel Palma, João Anselmo, J Porto, João Pedro Ramos, João Sequeira Duarte, Jorge Pintado Alves, José Miguel Salgado, José Pereira de Moura, Leonor Sassetti, Lina Cardoso Ramos, Luísa Diogo, Luísa Mota‐Vieira, Luísa Pires, Márcio de Moura, Margarida Bruges, Margarida Venâncio, Maria do Rosário Barroso, Maria João Virtuoso, Maria Luísa Gonçalves, Mário Oliveira, Mendes Nunes, J.M. Costa, Miguel Mendes, Miguel Toscano Rico, Mónica Tavares, Natalina Miguel, Oana Moldovan, Olga Azevedo, Patrícia Lipari Pinto, Patrícia Pais, Patrícia Freire de Vasconcelos, Paula Garcia, Paula Martins, Pedro Silva Cunha, P. S. Lemos, Quitéria Rato, Raquel Coelho, Raquel Gouveia Silva, Raquel Ribeiro, Rita Jotta de Oliveira, Roberto Magalhães Pinto, Sandra de Souza Pereira, Sérgio Ferreira Cristina, Sílvia Sequeira, Susana Correia, Tânia Vassalo, Tiago Pack, Vânia Martins, Vera Frazão Vieira,
Abstract Familial Hypercholesterolemia (FH) is a common genetic disorder of lipid metabolism caused by pathogenic/likely pathogenic variants in LDLR , APOB and PCSK9 genes. Variants in FH-phenocopy genes ( LDLRAP1 , APOE , LIPA , ABCG5 , ABCG8 ), polygenic hypercholesterolemia and hyper-Lp(a) can also mimic a clinical FH phenotype. We aim to present a new diagnostic tool to unravel the genetic background of clinical FH phenotype. Biochemical and genetic study was performed in 1005 individuals with clinical diagnosis of ...
Tópico(s): Cancer, Lipids, and Metabolism
2023 - Elsevier BV | Journal of Lipid Research
Paula Ministro, Cláudia Camila Dias, Francisco Portela, Samuel Fernandes, Sónia Bernardo, F.M. Andrade Pires, Paula Lago, Isadora Rosa, Eunice Trindade, Catarina Alves, L Correia, Fernando Magro,
Patients with elderly-onset inflammatory bowel disease were previously associated with a less aggressive course of the disease. However, there are conflicting data that need further validation. We aimed to determine the association between age at diagnosis and the development of progressive disease in patients with Crohn's disease (CD) and ulcerative colitis (UC).This cohort study included patients with CD and UC followed in 6 secondary and tertiary care centers in mainland Portugal. Patients were ...
Tópico(s): Eosinophilic Esophagitis
2021 - Lippincott Williams & Wilkins | Clinical and Translational Gastroenterology
María Isabel Prudêncio, María Isabel Dias, C.I. Burbidge, Zsolt Kasztovszky, Rosa Marques, J.G. Marques, Guilherme J. O. Cardoso, M.J. Trindade, Boglárka Maróti, Francisco Ruiz Muñoz, Lurdes Esteves, María Antonia Pinto de Matos, Alexandre Pais,
Tópico(s): Archaeology and ancient environmental studies
2015 - Springer Science+Business Media | Journal of Radioanalytical and Nuclear Chemistry
Mafalda Santiago, Fernando Magro, L Correia, Francisco Portela, Paula Ministro, Paula Lago, Eunice Trindade, Cláudia Camila Dias,
We aimed to describe the burden of rehospitalization in patients with inflammatory bowel disease (IBD), by evaluating rehospitalization rates, charges, and risk factors over 16 years.We performed a retrospective analysis of all hospital discharges with a primary diagnosis of IBD in public hospitals between 2000 and 2015 in mainland Portugal from the Central Administration of the Health System (ACSS)'s national registry. We collected data on patient, clinical, and healthcare charges. We used survival ...
Tópico(s): Appendicitis Diagnosis and Management
2020 - SAGE Publishing | Therapeutic Advances in Gastroenterology
F.I.G.M. Borges, S. J. C. do Carmo, T.H.V.T. Dias, F.P. Santos, Francisco Gil, A. Trindade, R. M. Curado da Silva, C.A.N. Conde,
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Tópico(s): X-ray Spectroscopy and Fluorescence Analysis
2007 - Cambridge University Press | Powder Diffraction