Jeremy Rundall, Edward Lucie-Smith, Alan Owens, Andre Breton, J. J. R. Trethowan, Charles Raw, Elizabeth Nicholas, Harold Hobson, Kay Dick, Antony Terry, Roger Nuttall, Adrian Mitchell, Gerry Hagon, Denis Young, Julian Symons, Frederic Raphael, Cal McCrystal, George Bruce, (Mrs) M J Brown, Hobart Rowen, Elizabeth Good, Henry Brandon, H V Rose, John Russell, Jack Cox, John Davenport, (Rev) G Dennis Spiller, (Miss) Violet M Newman, Max Marquis, Hugh Wynn, Barbara Bray, Philip Clarke, Derek Jewell, Patrick Campbell, Frank Dickens, Vivian Jenkins, Brian Inglis, Frank Giles, E G, Bryan Silcock Science Correspondent, Robin Marlar, Robert Troop, Dan van der Vat, Malcolm Southan, Stella Frank, Cyril Connolly, Robert Blackburn, J M Leggate, Anthony Vice, Colin Chapman Education Correspondent, Raymond Mortimer, David Holden, Maxwell Boyd, Evelyn Irons, Nicholas Evans, Alastair Buchan, Maurice Newrick Assistant Secretary, (Mrs) Margaret Orford, J L Harkness Chairman, Peter Wilsher, Arthur Koestler, Bryan Silcock, Michael Limb, Roger Mortimer, Malcolm Payne, James Wilson, Ernestine Carter, John Postgate, Desmond Shawe-Taylor, Peter Levi S J, J H Millar, Stephen Aris, Lanning Roper, Dilys Powell, John Richardson, E B Chain, David Wiggins, Hugo Young, (Miss) W M Yates Headmistress, Felix Aprahamian, Jack Fingleton, Benjamin Pogrund, Margaret Costa, Ian Coulter Industrial Correspondent, J W Lambert, Henry Longhurst, Dr Alfred Byrne Medical Correspondent, James Margach Political Correspondent, Christopher Ricks, Hunter Davies, F R, Michael Moynihan, Brian Glanville, Keith Richardson, Rev M C D'Arcy S J, Michael Green, G H D Legard, C. H. O'd. Alexander, Maurice Wiggin, Norman Moss, Gordon Ross, (Mrs) Myrtle Shaw, Philip Jacobson, Kenneth Konstam, (Rev) Michael Austin, John Mattison, David Ashton, Muriel Bowen, Nicholas Tomalin,
... Organisation Danish Tourist Bureau Ltd. Fly British Eagle Grimaldi-Siosa Lines Ltd Multiple Classified Advertising Items Escombe, ... Advertising Items Washington New York Chicago and San Francisco Laporte Chance of a Lifetime Limmer and Trinidad ...
1965 - Gale Group | Sunday Times HA GDA
Produção Nacional
Karen Friedrich, Flávia A. Vieira, Renato Porrozzi, Renato Sérgio Marchevsky, Norbert Miekeley, Gabriel Grimaldi, Francisco José Roma Paumgartten,
Abstract Antimony (Sb) disposition and toxicity was evaluated in Leishmania braziliensis-infected monkeys (Macaca mulatta) treated with a 21-d course of low (LOW) or standard (STD) meglumine antimoniate (MA) dosage regimens (5 or 20 mg SbV/kg body weight/d im). Antimony levels in biological matrices were determined by inductively coupled plasma mass spectrometry (ICPMS), while on-line ion chromatography coupled to ICPMS was used to separate and quantify Sb species in plasma. Nadir Sb levels rose steadily ...
Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes
2011 - Taylor & Francis | Journal of Toxicology and Environmental Health
Serge Conein, John Dugdale, Michael Prescott, Thomas Keneally, Philip Marsden, S Webster, David Downing, Matthew Wall, Scott Athorne, Barbara Hall, Nigel Botherway, Martin Narey, Steve Jones, Francois Pienaar, Emma Payne, Rosie Waterhouse, Emma Elliot, Nicholas Rufford, John Peter, Colin Haine, Emma Moore, Amanda Ursell, Lesley White, John Jay, J D, Laura Mercler, Max Glaskin, Nick Rufford, Lee Brown, Frank Whitford, Ivo Tennant, colin Jahoda, David Hinchliffe, Alistair Scott, Susan Bell, Sally Payne, David Smith, Kirstie Hamilton City Editor, Anthony Lawson, Malcolm Whitehead, Melanie Phillips, Nick Pitt, Neil Wormald, E P, Arthur Davies, Andrew Sullivan, Clive Davis, J Arch Getty, Stephen Grey, Mary Wilson, Dylan Jones, V W, Frank Gardner, Leslie Fraser-Mitchell, Jan Battles, Martin James, Simon Wilde, Tom Walker, Anthony Sattin, Iain Johnstone, Robert Winnett, Sir Alex Ferguson, Irwin Stelzer, Jane Moore, Peter Wilson, Roger Anderson, David Dougill, York Membery, Water Ellis, Norman Davies, John Evans, Dominic Tonner, Terry Leahy, Sarah Toyne, Marian Martin, David Hewson, Tania Alexander, Margaret Coles, Jonathon Carr-Brown, Alasdair Reid, Hugh Mcllvanney, Margarette Driscoll, Peter Watson, Jeremy Clarkson, Nigel Williams, David Cairns, Edward Porter, Hugh Canning, Louise Taylor, Estelle Doyle, John Waples Deputy City Editor, Stewart Lee, Lord Palumbo's, Jane Renton, Paul Eddy, Eben Black, Allan McFaul, John Deamer, Denia Wigram, Josh Hammond, Sally Kinness, Andrew Barr, Phil Craigie, Melaine McFadyean, Nick Gardner, Ian Robinson, Reg Staunton, Frederick Kempe, Chris Nowakowski, Hannah Cleaver, John Button, Peter Parker, Phillip Oppenheim, Paul Ham, Sue Evans, Josephine Smit, P Newta, Sue Lawrence, Below, Paul Driver, Boris Schapiro, Michael Woodhead, Maeve Sheehan, John Follain, Steven Downes, Richard Brooks, Shelley Von Strunckel, James Tooley, Christopher Morgan, David Leppard, Angle Buttrose, Edward Costello, Mrs J M Clarke, Alicia Wyllie, Sue Beenstock, Mark Edwards, Kirstie Hamilton, Jeremy Isaacs, Susan Clark, Paul Smyth, John Humphyrs, Steven Pinker, Danny O'Brien, Cliff Richard, Allstair Scott, Michael Heseltine Mp, Michael Winner, Hugo Barnacle, David Cage, Matthew Kalman, Anthony Grayling, Alan Combes, Meurice Chittenden, Sue Reid, Jonathon Green, Anna Pasternak, Raymond Keene, Nigel Sitwell, Cosmo Landesman, Zoe Brennan, Greg Hadfield, Diana Wright, Oleg V Naumov, Andy Knott, Phillips Faber, Andrew Drummond, Stephen Jones, Richard Evans, Nick Cain, Peta Bee, Robbie Cooper, Michael Bartlett, Natalie Graham, Paul Nuki, Caroline Donald, Dominic Rushe, Keith Wheatley, Claire Oldfield, Anna Greening, David Walsh, Name Withheld, A Bergin, Waldemar Januszcak, Jack Grimston, S P, Bryan Appleyard, Colin McDowell, M Smith, Tim Fenton, Stephen Armstrong, Ron Clarke, Caroline Seed's, Christopher Goodwin, Paul Kavanagh, Donovan Winter, John Stirling, Mark Prigg, Nick Harvey, Richard Woods, Nicholas Snowman, Garth Alexander, David Windle, Jeff Bezos, lan McEwan, Kim Fletcher, Maurice Chittenden, Kevin Pratt, Andrew Lorenz Business Editor, Graham Hind, Mark Franchetti, Jonathan Powell, Ray Hutton, Jon Ungoed-Thomas, Jonathan Leake, Tara Palmer-Tomkinson, John Crossland, Michael Sheridan, John Harlow, Peter Clarke, Godfrey Smith, Michael Barber, A B, John Waples, A A Gill, Joanna Owen, Matthew Campbell, Brian Glanville, Denis Walsh, E Hott, Nadine Meisner, Brian Brivati, Darren Evans, F Little, R Mulcahy, Chrissy Iley, Stephen Pettitt, Eva Pascoe, Kevin Goldstein-Jackson, Robert Johnston, Jeremy Langmead, Angie Buttrose, Sally Kinnes, Andrew Lorenz, Naomi Caine, Jane Hardy, Professor Ian Craft, Roger Dobson, Tom Rhodes, John Aizlewood, Chrsitopher Somerville, Nicholas Hellen Media Correspondent, Joe Lovejoy, Rupert Steiner, Valerie Grove, Gordon Brown, Hugh Pearman, Dan Cairns, K Devani, David Parsley, R Kaberry, David Smith Economics Editor, Penny Perrick, Tom Wolfe, Simon Crerar, Peter Roebuck, Bob Dwyer, James Gibb, India Knight, Steve Grant, Sandy Gall, Simon Howard, Danny Danziger, Rupert Halden, Georgina Howell, John Ramwell,
... Picture Gallery Cost of passports to rise Le Grimaldi claims it is Nice's first… Where was ... week's theatre Ariom "Visionary" Grand finale San Francisco Ballet's Swan Lake proved an unexpected delight, ...
1999 - Gale Group | Sunday Times HA GDA
Christian Domingo, T. Carrillo Díaz, Marina Blanco–Aparicio, Eva Martínez Moragón, D Bañas Conejero, María Guadalupe Sánchez Herrero, Mariana Muñoz, Héctor Cabrerizo, Antonio Valero, Ebymar Arismendi, Irina Bobolea, Gemma López, Celia Pinedo, Francisco Javier González‐Barcala, Purificación Pérez-López-Corona, Jacinto Ramos‐González, Javier Martín-Puentes, Gregorio Soto-Campos, Francisco Pérez-Grimaldi, Inmaculada Lluch, Juan Luis García‐Rivero, Celia Gutierrez-Villegas, Idoia Salinas-Garrido, Cleofé Fernández-Aracil, Luís Puente‐Maestu, Walther Iván Girón, Ángela Gómez-Sacristán, Miguel Díaz-Palacios, Ethel Ibáñez-Echevarría, Irene De Lorenzo, Ana Sogo, Daniel Ross-Monserrate, Elena Prina, Eusebi Chiner‐Vives, Sandra Vañes, Rocío Magdalena Díaz-Campos, Ismael García‐Moguel, Carmen Montero, María Fernández-Marrube, Tamara Hermida-Valverde, Anaís Enríquez, Núria Marina-Malanda, Ana Gómez-Larrauri, Antonio García-Dumpiérrez, Rodolfo Castillo-Sainz, Nancy Ortega, Lourdes Almeida, Luis Cabanes, Santiago Quirce, Javier Domínguez‐Ortega, David Romero, Irene Hernández, Daniel Laorden, Carolina Cisneros, Antolín López-Viña, Andrea Trisán, Teresa Caruana-Careaga, Ana Gómez-Bastero, Lucía Marín-Barrera,
The efficacy of mepolizumab is well documented in severe eosinophilic asthma (SEA), although the stringent selection criteria adopted by SEA clinical trials limits the generalizability of results. Our study evaluated the effectiveness and safety of mepolizumab in patients with SEA in Spain. The primary efficacy endpoint was the change in the rate of clinically significant asthma exacerbations 12 months after starting mepolizumab compared to the baseline rate in the 12 months prior to treatment. Patients ...
Tópico(s): Respiratory and Cough-Related Research
2021 - Adis, Springer Healthcare | Drugs
Produção Nacional
Revisado por pares
Cathrine Axfors, Perrine Janiaud, Andreas M. Schmitt, Janneke van ‘t Hooft, Emily R. Smith, Noah Haber, Akin Abayomi, Manal Abduljalil, Abdulkarim Abdulrahman, Yeny Acosta‐Ampudia, Manuela Aguilar‐Guisado, Farah Al-Beidh, Marissa M. Alejandria, Rachelle N. Alfonso, Mohammad Ali, Manaf AlQahtani, Alaa M Alzamrooni, Juan‐Manuel Anaya, Mark Angelo C. Ang, Ismael F. Aomar, Luis E. Argumanis, Alexander Averyanov, Владимир П. Баклаушев, Olga Balionis, Thomas Benfield, Scott Berry, Nadia Birocco, Lynn Bonifacio, Asha C Bowen, Abbie Bown, Carlos Cabello-Gutiérrez, Bernardo Camacho, Adrián Camacho-Ortíz, Sally A. Campbell‐Lee, Damon H. Cao, Ana Cardesa, Jose M. Carnate, German Jr. J. Castillo, Rossana Cavallo, Fazle Rabbi Chowdhury, Forhad Uddin Hasan Chowdhury, Giovannino Ciccone, Antonella Cingolani, Fresthel Monica M. Climacosa, Veerle Compernolle, Carlo Francisco N. Cortez, Abel Costa Neto, Sergio D’Antico, James Daly, Franca Danielle, Joshua S. Davis, Francesco Giuseppe De Rosa, Justin T. Denholm, Claudia M. Denkinger, Daniël Desmecht, Juan Camilo Díaz-Coronado, Juan Alberto Díaz Ponce-Medrano, Anne–Françoise Donneau, Teresita Dumagay, Susanna Dunachie, Cecile C Dungog, Olufemi Erinoso, Ivy Mae S. Escasa, Lise J Estcourt, Amy Evans, Agnes Lorrainne M. Evasan, Christian J. Fareli, Verónica Fernández-Sánchez, Claudia Galassi, Juan Esteban Gallo, Patricia García, Patricia L. García, Jesus Antonio Chávez García, Mutien‐Marie Garigliany, Elvira Garza‐González, Deonne Thaddeus V. Gauiran, Paula Andrea Gaviria García, J.A. Girón González, David Gómez‐Almaguer, Anthony Gordon, André Gothot, Jeser Santiago Grass Guaqueta, Cameron Green, David Grimaldi, Naomi Hammond, Heli Harvala, Francisco M. Heralde, Jesica A. Herrick, Alisa M. Higgins, Thomas Hills, Jennifer Hines, Karin Holm, Ashraful Hoque, Eric A. J. Hoste, José María Ignacio García, Alexander Vladimirovich Ivanov, Maike Janssen, Jeffrey Jennings, Vivekanand Jha, Ruby Anne N. King, Jens Kjeldsen‐Kragh, Paul Klenerman, Aditya Kotecha, Fiorella Krapp, Luciana Labanca, Emma Laing, Mona Landin‐Olsson, Pierre-François Laterre, Lyn‐li Lim, Jodor Lim, Oskar Ljungquist, Jorge Llaca-Díaz, Concepción López-Robles, Salvador López-Cárdenas, Ileana López-Plaza, Josephine Anne Lucero, Maria Lundgren, Juan Macı́as, Sandy Maganito, Anna Flor G. Malundo, Rubén Manrique, Paola Manzini, Miguel Marcos, Ignacio Christian Marquez, Francisco Javier Martínez‐Marcos, Ana M. Mata, Colin McArthur, Zoe McQuilten, Bryan J. McVerry, David Menon, Geert Meyfroidt, Ma. Angelina L. Mirasol, Benoît Misset, James S. Molton, Alric V. Mondragon, Diana M. Monsalve, Parastoo Moradi Choghakabodi, Susan C. Morpeth, Paul Mouncey, Michel Moutschen, Carsten Müller‐Tidow, Erin R. Murphy, Tomé Najdovski, Alistair Nichol, Henrik Nielsen, Richard Novák, Matthew O’Sullivan, Julián Olalla, Akin Osibogun, Bodunrin Osikomaiya, Salvador Oyonarte, Juan Mauricio Pardo Oviedo, Mahesh Patel, David L. Paterson, Carlos Alberto Peña-Pérez, Ángel Augusto Pérez-Calatayud, Eduardo Pérez-Alba, Anastasia S. Perkina, Naomi Perry, Mandana Pouladzadeh, Inmaculada Poyato, David J. Price, Anne Kristine H. Quero, Md. Mafizur Rahman, M. S. Rahman, Mayur Ramesh, Carolina Ramírez‐Santana, Magnus Rasmussen, Megan Rees, Eduardo Magalhães Rego, Jason A. Roberts, David J. Roberts, Yhojan Rodríguez, Jesús Rodríguez‐Baño, Benjamin A. Rogers, Manuel Rojas, Alberto Romero-Palacios, Kathy Rowan, Fabio Saccona, Mehdi Safdarian, Maria Clariza M. Santos, Joe Sasadeusz, Gitana Scozzari, Manu Shankar‐Hari, Gorav Sharma, Tom Snelling, Alonso Soto, Pedrito Y. Tagayuna, Amy Tang, Geneva Tatem, Luciana Teofili, Steven Y. C. Tong, Alexis F. Turgeon, Januario D. Veloso, Balasubramanian Venkatesh, Yanet Ventura-Enríquez, Steve Webb, Lothar Wiese, Christian Wikén, Erica M. Wood, Gaukhar M. Yusubalieva, Kai Zacharowski, Ryan Zarychanski, Nina Khanna, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens,
Abstract Background Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to assess the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, using data from all available randomized clinical trials, including unpublished and ongoing trials (Open Science ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - BioMed Central | BMC Infectious Diseases
Julián Acosta, F. Grimaccia E. Alfassio Grimaldi, Francisco Dorr, Francisco Varela, Lucas Alessandro, María Teresa Goicochea, Diego Fernández Slezak, Mauricio Farez,
... nonacute headache diagnosis (P3.127)Julián Acosta, Francisco Grimaldi, Francisco Dorr, Francisco Varela, Lucas Alessandro, María Teresa Goicochea, ...
Tópico(s): Migraine and Headache Studies
2018 - Lippincott Williams & Wilkins | Neurology
Michele Callea, Diego Martinelli, Francisco Cammarata-Scalisi, Chiara Grimaldi, Houweyda Jilani, Piercesare Grimaldi, Colin E. Willoughby, Antonino Morabito,
Dyskeratosis congenital (DC) is the first genetic syndrome described among telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of reticulated pigmentation of skin lace, nail dystrophy and oral leukoplakia. The clinical presentation, however, is heterogeneous and serious clinical complications include bone marrow failure, hematological and solid tumors. It may also involve immunodeficiencies, dental, pulmonary and liver disorders, and other minor complication. Dyskeratosis ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2022 - Multidisciplinary Digital Publishing Institute | Genes
Produção Nacional
Revisado por pares
Alda Maria Da‐Cruz, Danilo V Filgueiras, Ziadir Francisco Coutinho, Wilson Mayrink, Gabriel Grimaldi, Paula Mello De Luca, Sergio C.F. Mendonça, S. G. Coutinho,
An atypical case of acquired immunodeficiency syndrome-associated mucocutaneous lesions due to Leishmania braziliensis is described. Many vacuolated macrophages laden with amastigote forms of the parasite were found in the lesions. Leishmanin skin test and serology for leishmaniasis were both negative. The patient was resistant to therapy with conventional drugs (antimonial and amphotericin B). Interestingly, remission of lesions was achieved after an alternative combined therapy of antimonial associated ...
Tópico(s): Trypanosoma species research and implications
1999 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Monaliza Ribeiro Mariano Grimaldi, Luci Maira Silva Gonçalves, Ana Carolina de Oliveira Silva Melo, Francisco Ivandi Melo, Adriana Sousa Carvalho de Aguiar, Morgama Mara Nogueira Lima,
Objetivos: implementar estratégia educativa sobre noções básicas de primeiros socorros com estudantes de escola pública e particular e verificar o conhecimento destes antes e após a intervenção educativa. Método: pesquisa quantitativa, descritiva, exploratória, realizada com 48 estudantes do nono ano. Para verificar o conhecimento, utilizaram-se dez questões objetivas e de múltipla escolha como pré e pós-teste. A coleta foi realizada de setembro a dezembro de 2016, totalizando seis encontros. Para ...
Tópico(s): Burn Injury Management and Outcomes
2020 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Revista de Enfermagem da UFSM
R. Solans-Laqué, María C. Cid, R. Blanco, Marina Blanco–Aparicio, Ismael García‐Moguel, E. Arismendi-Nuñez, Ana Noblejas Mozo, Francisco Perez-Grimaldi, M. Labradror-Horrillo, C. Domingo-Rivas, Georgina Espígol‐Frigolé, Fernando Sánchez-Toril, F. Ortíz-Sanjuán, José María Álvaro‐Gracia, Íñigo Rúa‐Figueroa,
... CSL, Vifor, Gebro-Pharma, Astra Zeneca, CSL Vifor, Francisco Perez-Grimaldi Astra-Zeneca, GSK, Sanofi, Novartis, Chiesi, Teva Esteve, menarini, Boehringer Ingelheim, Moises Labradror-Horrillo Astra-Zeneca, GSK, Novartis, Sanofi-Pasteur, GSK, Chistian Domingo-Rivas Almirall, Astra-Zenca, Boehringer-Ingelheim, Chiesi, GSK, Menarini, NOvartis, Pfizer, Georgina Espigol-Frigole GSK, Fernando Sanchez-Toril ALK, Astra-Zeneca, Chiesi, Faes, Novartis, Pfizer, Teva, Boehringer Ingelheim, Sanofi, Francisco Ortiz-Sanjuan GSK, Grunenthal, Jose-Maria Alvaro-Gracia ...
Tópico(s): Eosinophilic Esophagitis
2024 - BMJ | Annals of the Rheumatic Diseases
Thomas Higham, Katerina Douka, Rachel Wood, Christopher Bronk Ramsey, Fiona Brock, Laura Basell, Marta Camps, Álvaro Arrizabalaga Valbuena, Javier Baena Preysler, Cecilio Barroso Ruíz, Christopher A. Bergman, Coralie Boitard, Paolo Boscato, Miguel Ángel Cadrecha y Caparrós, Nicholas J. Conard, Christelle Draily, Alain Froment, Bertila Galván, Paolo Gambassini, Alejandro García Moreno, Stefano Grimaldi, Paul Haesaerts, Brigitte Holt, María José Iriarte Chiapusso, Arthur J. Jelinek, Jesús Francisco Jordá Pardo, José‐Manuel Maíllo‐Fernández, Anat Marom, Julià Maroto, Mario Menéndez, Laure Metz, Eugène Morin, Adriana Moroni, Fabio Negrino, Eleni Panagopoulou, Marco Peresani, Stéphane Pirson, Marco de la Rasilla Vives, Julien Riel‐Salvatore, Annamaria Ronchitelli, David Santamaría Álvarez, Patrick Semal, Ludovic Slimak, Joaquim Soler Massana, Narcís Soler, Aritza Villaluenga, Ron Pinhasi, Roger Jacobi,
Tópico(s): Forensic Anthropology and Bioarchaeology Studies
2014 - Nature Portfolio | Nature
Rubén Rodríguez Casañ, Enrique García-Vidal, Didier Grimaldi, Carlos Carrasco, Francisco Vaquer-Estalrich, Joan Vila‐Francés,
The impact of the social media (SM) has been seen on the one hand as the cause of large exacerbation of negative messages, responsible for massively harmful societal phenomenon against democracies. On the other hand, recent studies have begun to look at how these online channels were able to provide a new impulse in human communication. The novelty of our work resides on analysing several axes of polarizations related to different societal topics. We believe our approach to reflect a more complex ...
Tópico(s): Hate Speech and Cyberbullying Detection
2022 - Springer Science+Business Media | Social Network Analysis and Mining
Produção Nacional
Revisado por pares
M. C. A. Marzochi, S. G. Coutinho, Wilson Jacinto Silva de Souza, Luciano Medeiros de Toledo, Gabriel Grimaldi, Hooman Momen, Raquel da Silva Pacheco, Paulo Chagastelles Sabroza, Miguel A. de Souza, Francisco B. Rangel, Neide Cássia Tramontano,
Forty dogs from the periphery of the city of Rio de Janeiro were studied. All dogs where diagnosed as positive for leishmaniasis either parasitologically and/or serologically. Among them, 19 came from areas where only Visceral Leishmaniasis (VL) occurs (Realengo, Bangu, Senador Camará). Clinical signs of the disease were seen in 36.8% of the cases, including emaciation - 100%, lymphadenopathy and depilation - 85.7%. The other 21 dogs came from an area (Campo Grande) where both diseases (VL, and American ...
Tópico(s): Research on Leishmaniasis Studies
1985 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Victoria Abbing‐Karahagopian, Xavier Kurz, Frank de Vries, Tjeerd van Staa, Yolanda Escobar, Ulrik Hesse, Joerg Hasford, Liset van Dijk, Francisco J. de Abajo, J Weil, Lamiae Grimaldi‐Bensouda, Toine C. G. Egberts, Robert F. Reynolds, Olaf H. Klungel,
Background: Observational pharmacoepidemiological (PE) studies on drug safety have produced discrepant results that may be due to differences in design, conduct and analysis. Keywords: Adrenergic beta-agonists, anti-bacterial agents, anticonvulsants, antidepressive agents, benzodiazepines, bone, calcium channel blockers, drug toxicity, european medicines agency, fractures, liver injury, myocardial infarction, neoplasms, observational studies, pharmacoepidemiology, suicide.
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2014 - Bentham Science Publishers | Current Clinical Pharmacology
Francisco Ramirez, Pedro Palominos, Maurício Camargo, Didier Grimaldi,
According to a forecast by the United Nations, by 2030 one in every three people in the world will live in cities with at least half a million inhabitants. Therefore, enabling smarter and resilient cities is one of the key goals to tackling world challenges and ensuring the citizen’s wellbeing in the years to come. Various frameworks of indicators have been proposed to evaluate urban smartness with an aim to improve policymakers' actions. Nevertheless, recent research shows that despite efforts ...
Tópico(s): Land Use and Ecosystem Services
2021 - Elsevier BV | Sustainable Cities and Society
Gioṙgio Matteucci, Román Castañeda, Samuel Serna, Francisco F. Medina, Jorge Garcı́a-Sucerquia,
An experiment analogous to that devised by Grimaldi and subsequently repeated by Young to study the nature of light has been realized with electrons. Following the Grimaldi and Young line of thought, an original approach is presented to introduce undergraduate physics students to the wave behaviour of electrons. An electron microscope equipped with a low coherent source of electrons and a thin platinum wire, acting as an opaque obstacle, is used to reproduce the experimental conditions adopted by ...
Tópico(s): Experimental and Theoretical Physics Studies
2010 - IOP Publishing | European Journal of Physics
Christian Domingo, T. Carrillo Díaz, Marina Blanco–Aparicio, Eva Martínez Moragón, D Bañas Conejero, María Guadalupe Sánchez Herrero, Mariana Muñoz, Héctor Cabrerizo, Antonio Valero, Ebymar Arismendi, Irina Bobolea, Gemma López, Celia Pinedo, Francisco Javier González‐Barcala, Purificación Pérez-López-Carona, Jacinto Ramos‐González, Javier Martín-Puentes, Gregorio Soto-Campos, Francisco Pérez-Grimaldi, Inmaculada Lluch, Juan Luis García‐Rivero, Celia Gutierrez-Villegas, Idoia Salinas-Garrido, Cleofé Fernández-Aracil, Luís Puente‐Maestu, Walther Iván Girón, Ángela Gómez-Sacristán, Miguel Díaz-Palacios, Ethel Ibáñez-Echevarría, Irene De Lorenzo, Ana Sogo, Daniel Ross-Monserrate, Elena Prina, Eusebi Chiner‐Vives, Sandra Vañes, Rocío Magdalena Díaz-Campos, Ismael García‐Moguel, Carmen Montero, María Fernández-Marrube, Tamara Hermida-Valverde, Anaís Enríquez, Núria Marina-Malanda, Ana Gómez-Larrauri, Antonio García-Dumpiérrez, Rodolfo Castillo-Sainz, Nancy Ortega, Lourdes Almeida, Luis Cabanes, Santiago Quirce, Javier Domínguez‐Ortega, David Romero, Irene Hernández, Daniel Laorden, Carolina Cisneros, Antolín López-Viña, Andrea Trisán, Teresa Caruana-Careaga, Ana Gómez-Bastero, Lucía Marín-Barrera,
Tópico(s): Asthma and respiratory diseases
2021 - Adis, Springer Healthcare | Drugs
Produção Nacional
Revisado por pares
Gabriel Grimaldi, Renato Porrozzi, Karen Friedrich, Antônio Têva, Renato Sérgio Marchevsky, Flávia A. Vieira, Norbert Miekeley, Francisco José Roma Paumgartten,
ABSTRACT This study compared the efficacies of two N -methylglucomine antimoniate (MA) dose regimens for treating macaques with Leishmania braziliensis -induced chronic skin disease. Whereas all animals treated with the full dose (20 mg MA/kg/day) were cured, 50% of the monkeys receiving a low-dose regimen (5 mg MA/kg/day) relapsed. The antimony concentrations in macaque plasma and tissue samples were greater in the full-dose group than in that receiving a subtherapeutic MA regimen. Our data also suggest ...
Tópico(s): Trypanosoma species research and implications
2009 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Francisco Manzano Esperguel, Daniel Rebolledo Hernández, Omar Sagredo Mazuela,
El artículo analiza, mediante una perspectiva cualitativa y performática, la obra de etnoteatro "Zona de promesa", una pieza creada en 2020 que aborda, desde la experiencia de las comunidades, los conflictos socioambientales derivados de la contaminación industrial y la crisis hídrica que existe en Puchuncaví-Quintero y Petorca, respectivamente, en la zona central de Chile. Particularmente, se analiza cómo esta obra fue diseñada y puesta en práctica, enfatizando en la metodología usada por la compañía ...
Tópico(s): Extractivism and Socioeconomic Issues
2021 - | Sophia Austral
Produção Nacional
Revisado por pares
Ana Teresa Nogueira Dumans, Danielle Bertino Grimaldi, Carolina Furtado, Ednildo A. Machado, Francisco Prosdocimi,
The genome of the subsocial cockroach Nauphoeta cinerea was partially sequenced in one-twelfth of an Illumina HiSeq lane. The mitochondrial genome was assembled using MIRA software, yielding a circular molecule of 15,923 bp in length and deposited in GenBank under the accession number KY212743. As expected, the mitogenome contained 13 protein-coding genes, 22 transfer tRNAs and 2 ribosomal RNAs. The molecule was assembled using 35,163 sequencing reads of 120 bp each, resulting in ∼286.9× coverage ...
Tópico(s): Fossil Insects in Amber
2017 - Taylor & Francis | Mitochondrial DNA Part B
Neil R. Norcross, Beatriz Baragaña, Caroline Wilson, Irene Hallyburton, Maria Osuna‐Cabello, Suzanne Norval, Jennifer Riley, Laste Stojanovski, Frederick R. C. Simeons, Achim Porzelle, Raffaella Grimaldi, Sergio Wittlin, Sandra Duffy, Vicky M. Avery, Stephan Meister, Laura M. Sanz, Belén Jiménez-Díaz, Íñigo Angulo‐Barturen, Santiago Ferrer, María Santos Martínez, Francisco‐Javier Gamo, Julie A. Frearson, David W. Gray, Alan H. Fairlamb, Elizabeth A. Winzeler, David Waterson, Simon F. Campbell, Paul Willis, Kevin D. Read, Ian H. Gilbert,
In this paper we describe the optimization of a phenotypic hit against Plasmodium falciparum, based on a trisubstituted pyrimidine scaffold. This led to compounds with good pharmacokinetics and oral activity in a P. berghei mouse model of malaria. The most promising compound (13) showed a reduction in parasitemia of 96% when dosed at 30 mg/kg orally once a day for 4 days in the P. berghei mouse model of malaria. It also demonstrated a rapid rate of clearance of the erythrocytic stage of P. falciparum ...
Tópico(s): Hepatitis C virus research
2016 - American Chemical Society | Journal of Medicinal Chemistry
Agostino Di Ciaula, Leonilde Bonfrate, Piero Portincasa, C Appice, Anna Belfiore, Mario Binetti, G Cafagna, Giulio Campanale, Antonio Carrieri, Giuseppe Leonardo Cascella, Stefania Cataldi, Antonella Cezza, M Ciannarella, L Cicala, Felicia D’Alitto, A. Dell’Acqua, Maria Lucia Dell’Anna, M Diaferia, G Erroi, Flavia Fiermonte, I Galerati, M Giove, Luciano Grimaldi, C Mallardi, E Mastrandrea, G. D. Mazelli, G Mersini, Giovanni Messina, M Messina, A Montesano, Antonino Noto, M Novielli, Maddalena Noviello, Michele Palma, Vincenzo Ostilio Palmieri, Francesco Passerini, Francisco Perez, C Piró, Filomena Prigigallo, Stefania Pugliese, Oriana Rossi, Cristina Stasi, R Stranieri, G Vitariello,
Previous ecological studies suggest the existence of possible interplays between the exposure to air pollutants and SARS-CoV-2 infection. Confirmations at individual level, however, are lacking. To explore the relationships between previous exposure to particulate matter < 10 μm (PM10) and nitrogen dioxide (NO2), the clinical outcome following hospital admittance, and lymphocyte subsets in COVID-19 patients with pneumonia. In 147 geocoded patients, we assessed the individual exposure to PM10 and NO2 ...
Tópico(s): COVID-19 impact on air quality
2022 - Springer Science+Business Media | Environmental Science and Pollution Research
Produção Nacional
Revisado por pares
Gennaro De Pascale, Otávio T. Ranzani, Saad Nseir, Jean Chastre, Tobias Welte, Massimo Antonelli, Paolo Navalesi, Eugenio Garofalo, Andrea Bruni, Luís Coelho, Szymon Skoczyński, Federico Longhini, Fabio Silvio Taccone, David Grimaldi, Helmut J.F. Salzer, Christoph Lange, Filipe Froes, Antoni Artigas, Emili Dı́az, Jordi Vallés, Alejandro Rodríguez, Mauro Panigada, Vittoria Comellini, Luca Fasano, Paolo Soave, Giorgia Spinazzola, Charles‐Édouard Luyt, Francisco Álvarez-Lerma, Judith Marin, Joan Ramón Masclans, Davide Chiumello, Angelo Pezzi, Marcus J. Schultz, Hafiz Ahmed E. Mohamed, Menno M. van der Eerden, Roger A.S. Hoek, Diederik Gommers, Marta Di Pasquale, Rok Čivljak, Marko Kutleša, Matteo Bassetti, George Dimοpoulos, Stefano Nava, Fernando Ríos, Fernando G. Zampieri, Pedro Póvoa, Lieuwe D. J. Bos, Stefano Aliberti, Antoní Torres, Ignacio Martín‐Loeches,
The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in ...
Tópico(s): Antibiotic Use and Resistance
2017 - European Respiratory Society | ERJ Open Research
Agostinho Cordeiro, M Tiérrez Conde, João Pimentel Torres, Nuno Morais, Paulo Mota, Ana Rocha, Giovanni Grimaldi, Francisco Botelho, Vítor Hugo Nogueira, Estêvão Lima,
Introdução: A hemostase é uma questão central na cirurgia laparoscópica. Não há diretrizes claras quando se trata de escolher qual o instrumento de energia a utilizar. Este estudo compara a eficiência e segurança entre EnSeal® e LigasureTM na selagem de artérias e veias em um modelo porcino ex-vivo. Métodos: Os instrumentos foram comparados entre si em relação à velocidade de corte e à pressão de ruptura (burst pressure - BP) após a colheita do vaso. Os níveis de coagulação e corte dos geradores foram ...
Tópico(s): Body Contouring and Surgery
2018 - CIG Media Group | Acta Urológica Portuguesa
M. Grimaldi, Isolde Römer, M. T. González de Apodaca, Leticia Iturbe, I. D. Catania, Janneth González, R. Kölliker‐fres, George E. Barreto, Francisco Capani,
Perinatal asphyxia (PA) is a medical condition associated with a high short-term morbimortality and different long-term neurological diseases. In previous work we have observed at 6 months post-synaptic densities (PSDs) alterations compatible with neurodegeneration highly correlated with the increment in the ubiquitination. Although alterations in the synaptic organization and function have been related with neuronal death after hypoxia, little is known about the synaptic changes in young animals ...
Tópico(s): Neuroscience and Neuropharmacology Research
2012 - Taylor & Francis | Nutritional Neuroscience
Produção Nacional
Revisado por pares
Fabio Vescini, Roberto Attanasio, Balestrieri Antonio, Francisco Bandeira, Stefania Bonadonna, Valentina Camozzi, Sara Cassibba, Roberto Cesareo, Iacopo Chiodini, C M Francucci, Laura Gianotti, Franco Grimaldi, Rinaldo Guglielmi, Bruno Madeo, Claudio Marcocci, Andrea Palermo, Alfredo Scillitani, Edda Vignali, Vincenzo Rochira, Michele Zini,
Treatment of osteoporosis is aimed to prevent fragility fractures and to stabilize or increase bone mineral density. Several drugs with different efficacy and safety profiles are available. The long-term therapeutic strategy should be planned, and the initial treatment should be selected according to the individual site-specific fracture risk and the need to give the maximal protection when the fracture risk is highest (i.e. in the late life). The present consensus focused on the strategies for the ...
Tópico(s): Estrogen and related hormone effects
2016 - Springer Science+Business Media | Journal of Endocrinological Investigation
Jeffrey A. Sosman, Mario Sznol, David F. McDermott, Richard D. Carvajal, Donald P. Lawrence, Suzanne L. Topalian, Jon M. Wigginton, Georgia Kollia, Amod Gupta, F. Stephen Hodi, Ralf Gutzmer, L. Rivoltini, E. Yu. Levchenko, Alessandro Testori, Jochen Utikal, P.A. Ascierto, Bruno Salaun, Nicolas Vanhoutte, M. Gillet, Vincent Brichard, G.J. Weiss, Anthony E. Oro, Anne Lynn S. Chang, James Solomon, P. LoRusso, O. Hamid, D.M. Chen, Edward McKenna, Shiqing Feng, John D. Hainsworth, Aleksandar Sekulić, Michael R. Migden, Karl D. Lewis, Simon Yoo, L. Dirix, Jian Hou, Haizhen Yue, A. Hauschild, Justin Rendleman, S. Shang, Christine Brocia, Michelle Ma, Richard L. Shapiro, Russell S. Berman, Anna C. Pavlick, Yu‐Hsuan Joni Shao, Iman Osman, Tomas Kirchhoff, Kalijn F. Bol, Erik H.J.G. Aarntzen, W.R. Gerritsen, Gerty Schreibelt, Jamie M. Jacobs, Wilco Lesterhuis, Michelle van Rossum, C.J.A. Punt, Carl G. Figdor, Jolanda De Vries, John F. Thompson, Michael Gordon, Jedd Wolchok, Percy Rojas, J. D. Schwartz, A. Y. Bedikian, Célèste Lebbe, J.S. Weber, M. Maio, Bart Neyns, Kaan Harmankaya, Kevin M. Chin, Diane Opatt McDowell, L. Cykowski, M. Brent McHenry, J. D. Wolchok, Anna Maria Di Giacomo, Luana Calabrò, Riccardo Danielli, Isabella Pesce, Ester Fonsatti, Erica Bertocci, Diana Giannarelli, M. Biagioli, Maresa Altomonte, M. Colombino, Maria Cristina Sini, Vincenzo De Giorgi, A. Lissia, Daniela Massi, Corrado Rubino, Antonio Cossu, Fabio Ayala, G. Palmieri, Ericka Francislaine Dias Costa, Gustavo Jacob Lourenço, Conceição Maria de Oliveira, José Augusto Rinck‐Junior, Aparecida Machado de Moraes, G.A.S. Nogueira, C.S.P. Lima, Mario Mandalà, G. Imberti, Dario Piazzalunga, R. Labianca, Gaetano Lucisano, Barbara Merelli, Stefania Mosconi, Luca Marchesi, Andrea Gianatti, Carlo Tondini, Maria Letícia Cintra, Tania Labiano, María D. Lozano, José I. Echeveste, M. Domingo Montañana, Miguel F. Sanmamed, Eduardo Castañón Álvarez, Nerea Gómez, Alfonso Gúrpide, Miguel Á. Idoate, Salvador Martín‐Algarra, Christian U. Blank, M. Del Vecchio, P. Queirolo, Ana Arance, Michael Brown, Lada Mitchell, L. Véronèse, J. Larkin, R. Dummer, Simone M. Goldinger, Christian P. Turtschi, N. Eggmann, Olivier Michielin, Paul R. Hilfiker, Jeannine D. Rinderknecht, Shalin S. Patel, R. Bassett, Wuh‐Liang Hwu, K. Kim, Nicolas Papadopoulos, Wuh‐Liang Hwu, Igor G. Bondarenko, C. Robert, L. Thomas, C. Garbe, Stephen Francis, Vanna Chiarion‐Sileni, F. De Galitiis, Laura Ridolfi, Francesco Cognetti, M.G. Bernengo, Diana M. Lawrence, Jessica Richards, Ali Amin, Katherine Bennett, Ágnes Balogh, Ester Simeone, C. Nuzzo, G. Rinaldi, R. Marconcini, Jacopo Pigozzo, Pier Francesco Ferrucci, Massimo Aglietta, L. Di Guardo, V. Ferraresi, Francesco De Rosa, Michele Guida, Silvia Stragliotto, V. Chairion Sileni, Lorenzo Pilla, S.V.L. Nicoletti, David S. Lee, L. Pericleous, M. Lebmeier, Bryan J. Winn, A. Batty, E Nikoglou, Antonio Cramarossa, Mario Petrillo, A Albano, Salvatore Pisconti, Michele Aieta, Michele Traversa, Ruggero Ridolfi, G. Colucci, Alejo Rodríguez‐Vida, E Muñoz, María Ochoa de Olza, Silvia Rossi, Cristina Gámez, J. Maria Caminal Mitjana, Jesús Pérez, J. Cortes, J.M. Piulats, Sanjiv S. Agarwala, John F. Thompson, B. Mark Smithers, Michael W. Ross, Brendon J. Coventry, David R. Minor, Charles R. Scoggins, Eric A. Wachter, Igor Samoylenko, Т. Н. Заботина, Irina N. Mikhaylova, George Chkadua, О. В. Короткова, К. А. Барышников, Lev Demidov, Sara Valpione, C. Aliberti, Edoardo Midena, Raffaele Parrozzani, Pierluigi Pilati, L Campana, H. Richard Alexander, Ryuichi Tanaka, Yumi SASAJIMA, H. Tsuda, K. Namikawa, Arata Tsutsumida, N. Yamazaki, Donna Rowen, Katrin Conen, Natalie Fischer, Günther F.L. Hofbauer, Bahar Shafaeddin-Schreve, R. Wintherhalder, C. Rochlitz, Alfred Zippelius, Michael Novy, Gernot Kriegshäuser, B. Rauscher, C. Oberkanins, Susan Murray, Helena Linardou, Fotios Siannis, D. Bafaloukos, I. Lazarev, Alexander Yakobson, Samuel Ariad, M Maur, E. Bajetta, Heather M. Shaw, Pippa Corrie, Sarah Ellis, Jenny Nobes, Emily Marshall, Surender Kumar, Sarah Danson, R. Plummer, P. Nathan, Lorenzo Alonso, Javier Valdivia, A. García Castaño, V. Javier Escrig, P. Mut, Anabel Ballesteros, Teresa Puértolas, E. Ortega, Alfonso Berrocal, José A. López-Martín, María González Cao, María Sereno, José Mayordomo, M. Rus Hidalgo, Begoña Campos, Dolores Rodríguez Cumplido, Francisco Zambrana, Javier Medina, Lucia Benedetto, Giusy Gentilcore, Corrado Caracò, Gianluca Di Monta, Ugo Marone, Antonio M. Grimaldi, Shinsuke Mori, Nicola Mozzillo, Wei-Tun Chang, Jongmin Lee, Sue J. Lee, Sunmin Park, Monica Choi, J.Y. Hong, Yongsoo Kim, Chi Hoon Maeng, Sang Bum Kim,
Elsevier BV
Manuel Garcı́a Ramı́rez, Manuel F. Martínez García, Ma Jesús Albar Marín, Inmaculada Dugo Benítez, Víctor M. Grimaldi Puyana, Francisco J. Santolaya Soriano,
Due to the important challenges which have been presented in the last years (immigration, economic globalization, wars, etc.) around the world, the European welfare model has been placed in a difficult situation, one which is more serious in Andalusia, one of the poorest regions in the current European Union. The Welfare Services Network (WSN) is a set of community programs focused on repairing the social inequalities and assuring community inclusion. Currently, for coping with new challenges, the ...
Tópico(s): Labor Law and Work Dynamics
2003 - | APUNTES DE PSICOLOGÍA
Sandro Mazzaferro, Lida Tartaglione, C Cascone, Nicola Di Daniele, Antonello Pani, Massimo Morosetti, M Francisco, Maurizio Nordio, Maria Silvana Leonardi, Mauro Martello, Cristina Grimaldi, Mario Cozzolino, Silverio Rotondi, Marzia Pasquali,
Tópico(s): Genetic Syndromes and Imprinting
2018 - Springer Science+Business Media | Journal of Nephrology
Produção Nacional
Revisado por pares
Rafaela Koehler Zanella, Denis Souto Valente, Léo Francisco Doncatto, D. Rossi, Aline Grimaldi Lerias, Alexandre Vontobel Padoin,
Vitamin D (VD) plays a role in the skin regulation. Striae Distensae (SD) are manifestations of epidermal atrophy that occurs after tissue tearing due to overstretching or rapid growth. The objective of this study was to investigate the relation between serum VD and occurrence of SD in women who had undergone mammaplasty with silicone implants. A case-referent study was conducted. The blood values of 25-hydroxyvitamin D (25OHD) were measured before the surgery. For each patient postoperatively diagnosed ...
Tópico(s): Acne and Rosacea Treatments and Effects
2015 - Hindawi Publishing Corporation | Dermatology Research and Practice